Change in health-related quality of life and functional disability over time post-concussion in youth
ConclusionConcussions have a negative impact on overall and physical HRQOL and functional disability in youth acutely post-injury. Ratings of HRQOL could be used to inform clinical treatment decisions to assist with the recovery process. (Source: Quality of Life Research)
Source: Quality of Life Research - November 3, 2023 Category: Health Management Source Type: research

Supportive care needs in Australian melanoma patients and caregivers: results from a quantitative cross-sectional survey
ConclusionAustralian melanoma patients and caregivers report substantial unmet supportive care needs, particularly regarding their psychological and emotional well-being. Psychological and emotional well-being services, such as access to a clinical psychologist or implementation of patient-reported outcome measures, should be incorporated into routine melanoma care to address unmet patient and caregiver needs and improve well-being. (Source: Quality of Life Research)
Source: Quality of Life Research - November 3, 2023 Category: Health Management Source Type: research

Effects of esketamine on patient-reported outcomes in major depressive disorder with active suicidal ideation and intent: a pooled analysis of two randomized phase 3 trials (ASPIRE I and ASPIRE II)
ConclusionThese PRO data support the patient perspective of the effect associated with esketamine  + SOC in improving health-related QoL in patients with MDSI.Trial registration: ClinicalTrials.gov Identifier: ASPIRE I, NCT03039192 (Registration date: February 1, 2017); ASPIRE II, NCT03097133 (Registration date: March 31, 2017). (Source: Quality of Life Research)
Source: Quality of Life Research - September 30, 2023 Category: Health Management Source Type: research

Health-related quality of life profiles in adolescents and young adults with chronic conditions
ConclusionsApproximately half of AYAs with a chronic condition experience moderate to severe HRQOL impact. The availability of risk prediction models for HRQOL impact will help to identify AYAs who are in greatest need of closer clinical care follow-up. (Source: Quality of Life Research)
Source: Quality of Life Research - September 30, 2023 Category: Health Management Source Type: research

Quality of life in the year after new diagnosis with advanced prostate cancer for Black and White individuals living in the US
ConclusionThere are notable differences in quality of life at new diagnosis of advanced prostate cancer for Black and White individuals, and quality of life declines similarly in the first year for both groups. Interventions that address specific aspects of quality of life in these patients could meaningfully improve the overall survivorship experience. (Source: Quality of Life Research)
Source: Quality of Life Research - September 30, 2023 Category: Health Management Source Type: research

Associations between treatments, comorbidities and multidimensional aspects of quality of life among patients with advanced cancer in the Netherlands —a 2017–2020 multicentre cross-sectional study
ConclusionOur study identified associations between specific cancer treatments, lower QoL and more symptoms. Monitoring symptoms may improve QoL of patients with advanced cancer. Producing more evidence from real life data would help physicians in better identifying patients who require additional supportive care. (Source: Quality of Life Research)
Source: Quality of Life Research - September 30, 2023 Category: Health Management Source Type: research

Social factors of health-related quality of life in older adults: a multivariable analysis
ConclusionSociodemographic, socioeconomic, psychosocial, and behavioural factors were associated with physical and mental HRQOL. These results highlight the importance of social factors in HRQOL and provide approaches for policy and practice to develop and implement tailored health interventions for older adults. Our findings may be transferable to municipalities in metropolitan areas of high-income European countries.Clinical trial registration: Not applicable. (Source: Quality of Life Research)
Source: Quality of Life Research - September 30, 2023 Category: Health Management Source Type: research

Health related quality of life in adults after late repair of tetralogy of fallot: experience from a low-middle income country
ConclusionOur results indicate that even with a delayed diagnosis, surgical repair of TOF produces good functional results. However, these patients face significant psychosocial issues. While early diagnosis remains the ultimate goal, patients undergoing late repair should be managed in more holistic manner with attention to psychological impact of the disease as well. (Source: Quality of Life Research)
Source: Quality of Life Research - September 30, 2023 Category: Health Management Source Type: research

Health-related quality of life among people who inject drugs in Australia
ConclusionsThe study findings provide important HRQoL data for economic evaluations, useful for guiding the allocation of resources for HCV elimination strategies and interventions among PWID. (Source: Quality of Life Research)
Source: Quality of Life Research - September 30, 2023 Category: Health Management Source Type: research

A systematic review of health state utility values and psychometric performance of generic preference-based instruments for children and adolescents with mental health problems
ConclusionThis review provides an overview of HSUVs of various MHPs, the current practice to generate HSUVs, and the psychometric performance of MAUIs used in children and adolescents with MHPs. It highlights the need for more rigorous and extensive psychometric assessments to produce evidence on the suitability of MAUIs used in this area. (Source: Quality of Life Research)
Source: Quality of Life Research - September 30, 2023 Category: Health Management Source Type: research

Response shift in parent-reported psychopathology in children with chronic physical illness
ConclusionsResponse shift detected on the conduct disorder subscale of the OCHS-EBS, indicated that parents of children with physical illness may recalibrate their responses on child psychopathology over 24  months. Researchers and health professionals should be aware of RS when using the OCHS-EBS to assess child psychopathology over time. (Source: Quality of Life Research)
Source: Quality of Life Research - September 30, 2023 Category: Health Management Source Type: research

Understanding the measurement relationship between EQ-5D-5L, PROMIS-29 and PROPr
DiscussionThere is some consistency in what the EQ-5D-5L, PROMIS-29 and PROPr measure. Differences between value set characteristics can be linked to differences what is measured and the valuation approaches used. This has implications for the use of each in assessing health outcomes, and the results can inform decisions about which instrument should be used in which context. (Source: Quality of Life Research)
Source: Quality of Life Research - September 30, 2023 Category: Health Management Source Type: research

Prevalent falls, fall frequencies and health-related quality of life among community-dwelling older Chinese adults
ConclusionFalls were negative associated with overall HRQOL as well as separate HRQOL dimensions among older adults. It also appears that the HRQOL influence on older men is more evident than older women. (Source: Quality of Life Research)
Source: Quality of Life Research - September 30, 2023 Category: Health Management Source Type: research

Determinants of health-related quality of life (HRQoL) among homeless individuals during the COVID-19 pandemic
ConclusionsOverall, our study findings showed a quite high HRQoL among homeless individuals during the COVID-19 pandemic in Germany. Some important determinants of HRQoL were identified (e.g., age or marital status). Longitudinal studies are required to confirm our findings. (Source: Quality of Life Research)
Source: Quality of Life Research - September 30, 2023 Category: Health Management Source Type: research

Effects of an autonomy-supportive intervention programme (ASIP) on self-care, quality of life, and mental health in heart failure patients: a randomized controlled trial
ConclusionIn summary, the 8-week HF-ASIP significantly improved the attributes of self-care, quality of life, mental health, and motivation in HF patients, suggesting the potential for practical intervention effect.Trial registrationChiCTR2100053970. (Source: Quality of Life Research)
Source: Quality of Life Research - September 30, 2023 Category: Health Management Source Type: research