Peripheral ulcerative keratitis associated with tralokinumab therapy: a case report and review of IL-13 inhibitor-associated ocular surface disease
ConclusionThis case report documents ulcerative keratitis occurring in association with tralokinumab therapy for AD, which has previously been described with dupilumab but not tralokinumab. This report demonstrates the need for vigilant ocular surface monitoring for patients on tralokinumab and illustrates successful management and long-term control of adverse ocular events associated with this medication. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - April 16, 2024 Category: Opthalmology Source Type: research

The CORE syndrome: an overlap of severe asthma, obstructive sleep apnea, rhinosinusitis, and esophageal reflux
ConclusionWhenever facing SA patients, non-responders to therapy, it is important to suspect the presence of CORE syndrome; in particular, the detection and subsequent treatment of OSA would seem to improve the outcome of such patients. (Source: Sleep and Breathing)
Source: Sleep and Breathing - April 16, 2024 Category: Respiratory Medicine Source Type: research

A case of celiac plexus block causing iatrogenic Cushing's syndrome
Key Clinical MessageTreatment with corticosteroids can lead to iatrogenic Cushing's syndrome when used for longer intervals and in high doses. Less common administration routes may conceal the exposure, raising the possibility of misdiagnosis and mismanagement. (Source: Clinical Case Reports)
Source: Clinical Case Reports - April 15, 2024 Category: General Medicine Authors: Ana ‐Maria Chindris, Sarika N. Rao, Razvan M. Chirila, Adrian G. Dumitrascu Tags: CASE REPORT Source Type: research

Efficacy of an aloe vera, chamomile, and thyme cosmetic cream for the prophylaxis and treatment of mild dermatitis induced by radiation therapy in breast cancer patients (the Alantel study)
CONCLUSIONS: The higher efficacy of Alantel® compared to the control cream in reducing the incidence of RD in women with breast cancer has been demonstrated.PMID:38616815 | PMC:PMC11010796 | DOI:10.1016/j.conctc.2024.101288 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - April 15, 2024 Category: Cancer & Oncology Authors: E Villegas-Becerril C Jimenez-Garcia L A Perula-de Torres M Espinosa-Calvo C M Bueno-Serrano F Romero-Ruperto F Gines-Santiago M C Moreno-Manzanaro J J Mu ñoz-Gavilan G Montes-Redondo M A Quesada-Roman M C Linares-Ramirez J M Parras-Rejano N Mu ñoz-Alca Source Type: research

Efficacy of an aloe vera, chamomile, and thyme cosmetic cream for the prophylaxis and treatment of mild dermatitis induced by radiation therapy in breast cancer patients (the Alantel study)
CONCLUSIONS: The higher efficacy of Alantel® compared to the control cream in reducing the incidence of RD in women with breast cancer has been demonstrated.PMID:38616815 | PMC:PMC11010796 | DOI:10.1016/j.conctc.2024.101288 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - April 15, 2024 Category: Cancer & Oncology Authors: E Villegas-Becerril C Jimenez-Garcia L A Perula-de Torres M Espinosa-Calvo C M Bueno-Serrano F Romero-Ruperto F Gines-Santiago M C Moreno-Manzanaro J J Mu ñoz-Gavilan G Montes-Redondo M A Quesada-Roman M C Linares-Ramirez J M Parras-Rejano N Mu ñoz-Alca Source Type: research

Repeated Pulses of Methyl-Prednisolone in Adults Hospitalized With COVID-19 Pneumonia and Acute Respiratory Distress Syndrome: A Preliminary Before-After Study (CortiCOVID Study)
CONCLUSIONS: In patients with severe pneumonia due to COVID-19, the administration of methylprednisolone pulses was associated with a lower rate of OTI and/or death and a shorter hospitalization episode.PMID:38620829 | PMC:PMC7977067 | DOI:10.1016/j.opresp.2021.100086 (Source: Respiratory Care)
Source: Respiratory Care - April 15, 2024 Category: Respiratory Medicine Authors: Michelle Espinosa-Solano Demetrio Gonzalez-Vergara Marta Ferrer-Galvan Maria Isabel Asensio-Cruz Jose M Lomas Cristina Roca-Oporto Maria Dolores Navarro-Amuedo Maria Paniagua-Garcia Cesar Sotomayor Nuria Espinosa Manuel Garcia-Gutierrez Jose Molina Gil-Be Source Type: research

Pulmonology: What You May Have Missed in 2023
Ann Intern Med. 2024 Apr 16. doi: 10.7326/M24-0613. Online ahead of print.ABSTRACTThe field of pulmonology saw significant advances in 2023. The publications highlighted in this article address advances and changes in practice related to asthma, chronic obstructive pulmonary disease (COPD), interstitial lung disease, pleural disorders, and sleep-disordered breathing. One article reviews data examining the efficacy of vaccination against respiratory syncytial virus, a respiratory viral illness that has had devastating effects globally. Four studies evaluate the role of various therapies in COPD, including dupilumab, ensifen...
Source: Annals of Internal Medicine - April 15, 2024 Category: Internal Medicine Authors: Aram Karkar Sana Khan Rebecca O'Leary Albina Tyker Michael Unger Source Type: research

Rational use of antibiotics treatment in acute bronchitis
Med Mal Infect. 1992 Feb;22:149-152. doi: 10.1016/S0399-077X(05)81464-7. Epub 2005 Jun 20.ABSTRACTAcute bronchitis in healthy patient in mainly related to virus. Intra-cellular bacteria, Mycoplasma pneumonia are rarely involved. For these reasons, macrolides or cyclines (except for children) are justified in first line treatment. For patients with acute exacerbation of chronic bronchitis, the choice of the treatment needs to be discuss. At the initial stage, most of the pathogens involved are those of acute bronchitis. Antibiotic is only prescribes for the prevention of a superinfection; this kind of prophylaxis has to be ...
Source: Medecine et Maladies Infectieuses - April 15, 2024 Category: Infectious Diseases Authors: P Dellamonica Source Type: research

Real-World Treatment Patterns and Healthcare Resource Use for Ulcerative Colitis and Crohn's Disease in Italy
CONCLUSION: This analysis, carried-out in an Italian clinical setting, may help to optimise therapy for patients with UC and CD and provide relevant clinical practice data to inform decision-makers.PMID:38619721 | DOI:10.1007/s12325-024-02840-x (Source: Adv Data)
Source: Adv Data - April 15, 2024 Category: Epidemiology Authors: Melania Dovizio Susanne Hartz Carlotta Buzzoni Isabel Redondo Marijana Nedeljkovic Protic Domenico Birra Valentina Perrone Chiara Veronesi Luca Degli Esposti Alessandro Armuzzi Source Type: research

Efficacy of an aloe vera, chamomile, and thyme cosmetic cream for the prophylaxis and treatment of mild dermatitis induced by radiation therapy in breast cancer patients (the Alantel study)
CONCLUSIONS: The higher efficacy of Alantel® compared to the control cream in reducing the incidence of RD in women with breast cancer has been demonstrated.PMID:38616815 | PMC:PMC11010796 | DOI:10.1016/j.conctc.2024.101288 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - April 15, 2024 Category: Cancer & Oncology Authors: E Villegas-Becerril C Jimenez-Garcia L A Perula-de Torres M Espinosa-Calvo C M Bueno-Serrano F Romero-Ruperto F Gines-Santiago M C Moreno-Manzanaro J J Mu ñoz-Gavilan G Montes-Redondo M A Quesada-Roman M C Linares-Ramirez J M Parras-Rejano N Mu ñoz-Alca Source Type: research

Efficacy of an aloe vera, chamomile, and thyme cosmetic cream for the prophylaxis and treatment of mild dermatitis induced by radiation therapy in breast cancer patients (the Alantel study)
CONCLUSIONS: The higher efficacy of Alantel® compared to the control cream in reducing the incidence of RD in women with breast cancer has been demonstrated.PMID:38616815 | PMC:PMC11010796 | DOI:10.1016/j.conctc.2024.101288 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - April 15, 2024 Category: Cancer & Oncology Authors: E Villegas-Becerril C Jimenez-Garcia L A Perula-de Torres M Espinosa-Calvo C M Bueno-Serrano F Romero-Ruperto F Gines-Santiago M C Moreno-Manzanaro J J Mu ñoz-Gavilan G Montes-Redondo M A Quesada-Roman M C Linares-Ramirez J M Parras-Rejano N Mu ñoz-Alca Source Type: research

Efficacy of tocilizumab in patients with moderate-to-severe corticosteroid-resistant thyroid eye disease: a prospective study
CONCLUSION: TCZ can treat active moderate-to-severe TED, showing high drug compliance and reasonable response to inflammation and extraocular motility abnormality.PMID:38622479 | DOI:10.1007/s10792-024-03117-6 (Source: Herpes)
Source: Herpes - April 15, 2024 Category: Infectious Diseases Authors: Chaeyeon Lee Ji Woong Park Yoon-Duck Kim Kyung In Woo Source Type: research

Pulmonology: What You May Have Missed in 2023
Ann Intern Med. 2024 Apr 16. doi: 10.7326/M24-0613. Online ahead of print.ABSTRACTThe field of pulmonology saw significant advances in 2023. The publications highlighted in this article address advances and changes in practice related to asthma, chronic obstructive pulmonary disease (COPD), interstitial lung disease, pleural disorders, and sleep-disordered breathing. One article reviews data examining the efficacy of vaccination against respiratory syncytial virus, a respiratory viral illness that has had devastating effects globally. Four studies evaluate the role of various therapies in COPD, including dupilumab, ensifen...
Source: Annals of Internal Medicine - April 15, 2024 Category: Internal Medicine Authors: Aram Karkar Sana Khan Rebecca O'Leary Albina Tyker Michael Unger Source Type: research

Real-World Treatment Patterns and Healthcare Resource Use for Ulcerative Colitis and Crohn's Disease in Italy
CONCLUSION: This analysis, carried-out in an Italian clinical setting, may help to optimise therapy for patients with UC and CD and provide relevant clinical practice data to inform decision-makers.PMID:38619721 | DOI:10.1007/s12325-024-02840-x (Source: Adv Data)
Source: Adv Data - April 15, 2024 Category: Epidemiology Authors: Melania Dovizio Susanne Hartz Carlotta Buzzoni Isabel Redondo Marijana Nedeljkovic Protic Domenico Birra Valentina Perrone Chiara Veronesi Luca Degli Esposti Alessandro Armuzzi Source Type: research