Ketorolac Injections for Musculoskeletal Conditions: A Narrative Review
Clin Med Res. 2024 Mar;22(1):19-27. doi: 10.3121/cmr.2024.1847.ABSTRACTMusculoskeletal conditions of the upper and lower extremities are commonly treated with corticosteroid injections. Ketorolac, a parenteral nonsteroidal anti-inflammatory drug, represents an alternative injectant for common shoulder, hip, and knee conditions. A review of the current literature was conducted on the efficacy of ketorolac injection in musculoskeletal diseases. Several studies support the use and efficacy of ketorolac injection in subacromial bursitis, adhesive capsulitis, and hip and knee osteoarthritis. Given the systemic effects of glucoc...
Source: Clin Med Res - April 12, 2024 Category: Research Authors: John Kiel Andres I Applewhite Tais G O Bertasi Raphael A O Bertasi LaRae L Seemann Lorena M C Costa Haytham Helmi George G A Pujalte Source Type: research

Idiopathic intracranial hypertension as the initial presenting manifestation of systemic lupus erythematosus in a child
We report a 12-year-old girl presented with chronic holocranial headache and occasional episodes of projectile vomiting for the last 6 months and then developed blurring of vision for the last month. She fulfilled the criteria for IIH. Subsequent evaluation revealed a diagnosis of SLE. The occurrence of IIH in SLE is not coincidental and is reported in 1%-5.4% of patients with SLE. Though corticosteroids have not been widely used in IIH, underlying SLE warranted administering corticosteroids with subsequent complete resolution of IIH. Pediatricians, neurologists, intensivists, and ophthalmologists should consider SLE as a ...
Source: Lupus - April 12, 2024 Category: Rheumatology Authors: Murugan Sudhakar Anu P Kocheril Anish S George George I Vettiyil Anitha Jasper Sathish Kumar Source Type: research

Polyposis of gastrointestinal tract after COVID-19 mRNA vaccination: a report of two cases
Clin Endosc. 2024 Apr 12. doi: 10.5946/ce.2023.268. Online ahead of print.ABSTRACTCronkhite-Canada syndrome is a rare gastrointestinal polyposis syndrome with distinctive clinical features and endoscopic findings. Diagnosis can be challenging without suspicion, and the disease carries high mortality due to complications such as infection, gastrointestinal bleeding, and malignancies. This paper presents two cases of Cronkhite-Canada syndrome occurring after coronavirus disease 2019 (COVID-19) mRNA vaccination. Both cases exhibited typical clinical findings, including hypogeusia, onychodystrophy, alopecia, and weight loss. T...
Source: Clinical Endoscopy - April 12, 2024 Category: Gastroenterology Authors: Jun Ho Kim Eun Hye Oh Dong Soo Han Source Type: research

Ultrasensitive cortisol electrochemical immunosensor amplifying by Au single-atom nanozymes and HRP enzymes
Anal Chim Acta. 2024 May 15;1303:342462. doi: 10.1016/j.aca.2024.342462. Epub 2024 Mar 11.ABSTRACTCortisol, a corticosteroid hormone as a primary stress hormone response to internal and external stress, has been regarded as a gold standard reliable biomarker to evaluate human mental stress. The double enzymes strategy, using nanozyme and enzyme amplifying the electrochemical signal, has been widely used to improve the performance of electrochemical biosensors. An ultra-sensitive electrochemical cortisol sensor based on Au single-atom nanozymes had been fabricated through HRP labeled anti-cortisol antibody binding with Au b...
Source: Analytica Chimica Acta - April 12, 2024 Category: Chemistry Authors: Yongling Du Min Guo Yan Chen Xiaohui Mo Junlei Cao Fangdi Hu Source Type: research

Treatment of Netherton Syndrome in Pediatrics with Upadacitinib
CONCLUSIONS: Initiation of Upadacitinib at a daily dose of 15 mg yielded significant therapeutic benefits within a short timeframe. This study marks the first documented use of Upadacitinib in pediatric Netherton syndrome treatment. This case highlights the efficacy of Upadacitinib in treating Netherton syndrome, particularly in pediatric patients. Further studies are warranted to elucidate its long-term effects and optimal dosing regimens.PMID:38607195 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 12, 2024 Category: Complementary Medicine Authors: Cuicui Sun Yongfeng Chen Source Type: research

Ketorolac Injections for Musculoskeletal Conditions: A Narrative Review
Clin Med Res. 2024 Mar;22(1):19-27. doi: 10.3121/cmr.2024.1847.ABSTRACTMusculoskeletal conditions of the upper and lower extremities are commonly treated with corticosteroid injections. Ketorolac, a parenteral nonsteroidal anti-inflammatory drug, represents an alternative injectant for common shoulder, hip, and knee conditions. A review of the current literature was conducted on the efficacy of ketorolac injection in musculoskeletal diseases. Several studies support the use and efficacy of ketorolac injection in subacromial bursitis, adhesive capsulitis, and hip and knee osteoarthritis. Given the systemic effects of glucoc...
Source: Clinical Medicine and Research - April 12, 2024 Category: General Medicine Authors: John Kiel Andres I Applewhite Tais G O Bertasi Raphael A O Bertasi LaRae L Seemann Lorena M C Costa Haytham Helmi George G A Pujalte Source Type: research

Polyposis of gastrointestinal tract after COVID-19 mRNA vaccination: a report of two cases
Clin Endosc. 2024 Apr 12. doi: 10.5946/ce.2023.268. Online ahead of print.ABSTRACTCronkhite-Canada syndrome is a rare gastrointestinal polyposis syndrome with distinctive clinical features and endoscopic findings. Diagnosis can be challenging without suspicion, and the disease carries high mortality due to complications such as infection, gastrointestinal bleeding, and malignancies. This paper presents two cases of Cronkhite-Canada syndrome occurring after coronavirus disease 2019 (COVID-19) mRNA vaccination. Both cases exhibited typical clinical findings, including hypogeusia, onychodystrophy, alopecia, and weight loss. T...
Source: Clinical Endoscopy - April 12, 2024 Category: Gastroenterology Authors: Jun Ho Kim Eun Hye Oh Dong Soo Han Source Type: research

Ultrasensitive cortisol electrochemical immunosensor amplifying by Au single-atom nanozymes and HRP enzymes
Anal Chim Acta. 2024 May 15;1303:342462. doi: 10.1016/j.aca.2024.342462. Epub 2024 Mar 11.ABSTRACTCortisol, a corticosteroid hormone as a primary stress hormone response to internal and external stress, has been regarded as a gold standard reliable biomarker to evaluate human mental stress. The double enzymes strategy, using nanozyme and enzyme amplifying the electrochemical signal, has been widely used to improve the performance of electrochemical biosensors. An ultra-sensitive electrochemical cortisol sensor based on Au single-atom nanozymes had been fabricated through HRP labeled anti-cortisol antibody binding with Au b...
Source: Analytica Chimica Acta - April 12, 2024 Category: Chemistry Authors: Yongling Du Min Guo Yan Chen Xiaohui Mo Junlei Cao Fangdi Hu Source Type: research

Ketorolac Injections for Musculoskeletal Conditions: A Narrative Review
Clin Med Res. 2024 Mar;22(1):19-27. doi: 10.3121/cmr.2024.1847.ABSTRACTMusculoskeletal conditions of the upper and lower extremities are commonly treated with corticosteroid injections. Ketorolac, a parenteral nonsteroidal anti-inflammatory drug, represents an alternative injectant for common shoulder, hip, and knee conditions. A review of the current literature was conducted on the efficacy of ketorolac injection in musculoskeletal diseases. Several studies support the use and efficacy of ketorolac injection in subacromial bursitis, adhesive capsulitis, and hip and knee osteoarthritis. Given the systemic effects of glucoc...
Source: Clinical Medicine and Research - April 12, 2024 Category: General Medicine Authors: John Kiel Andres I Applewhite Tais G O Bertasi Raphael A O Bertasi LaRae L Seemann Lorena M C Costa Haytham Helmi George G A Pujalte Source Type: research

Ultrasensitive cortisol electrochemical immunosensor amplifying by Au single-atom nanozymes and HRP enzymes
Anal Chim Acta. 2024 May 15;1303:342462. doi: 10.1016/j.aca.2024.342462. Epub 2024 Mar 11.ABSTRACTCortisol, a corticosteroid hormone as a primary stress hormone response to internal and external stress, has been regarded as a gold standard reliable biomarker to evaluate human mental stress. The double enzymes strategy, using nanozyme and enzyme amplifying the electrochemical signal, has been widely used to improve the performance of electrochemical biosensors. An ultra-sensitive electrochemical cortisol sensor based on Au single-atom nanozymes had been fabricated through HRP labeled anti-cortisol antibody binding with Au b...
Source: Analytica Chimica Acta - April 12, 2024 Category: Chemistry Authors: Yongling Du Min Guo Yan Chen Xiaohui Mo Junlei Cao Fangdi Hu Source Type: research

Ketorolac Injections for Musculoskeletal Conditions: A Narrative Review
Clin Med Res. 2024 Mar;22(1):19-27. doi: 10.3121/cmr.2024.1847.ABSTRACTMusculoskeletal conditions of the upper and lower extremities are commonly treated with corticosteroid injections. Ketorolac, a parenteral nonsteroidal anti-inflammatory drug, represents an alternative injectant for common shoulder, hip, and knee conditions. A review of the current literature was conducted on the efficacy of ketorolac injection in musculoskeletal diseases. Several studies support the use and efficacy of ketorolac injection in subacromial bursitis, adhesive capsulitis, and hip and knee osteoarthritis. Given the systemic effects of glucoc...
Source: Clinical Medicine and Research - April 12, 2024 Category: General Medicine Authors: John Kiel Andres I Applewhite Tais G O Bertasi Raphael A O Bertasi LaRae L Seemann Lorena M C Costa Haytham Helmi George G A Pujalte Source Type: research

Ketorolac Injections for Musculoskeletal Conditions: A Narrative Review
Clin Med Res. 2024 Mar;22(1):19-27. doi: 10.3121/cmr.2024.1847.ABSTRACTMusculoskeletal conditions of the upper and lower extremities are commonly treated with corticosteroid injections. Ketorolac, a parenteral nonsteroidal anti-inflammatory drug, represents an alternative injectant for common shoulder, hip, and knee conditions. A review of the current literature was conducted on the efficacy of ketorolac injection in musculoskeletal diseases. Several studies support the use and efficacy of ketorolac injection in subacromial bursitis, adhesive capsulitis, and hip and knee osteoarthritis. Given the systemic effects of glucoc...
Source: Clinical Medicine and Research - April 12, 2024 Category: General Medicine Authors: John Kiel Andres I Applewhite Tais G O Bertasi Raphael A O Bertasi LaRae L Seemann Lorena M C Costa Haytham Helmi George G A Pujalte Source Type: research

Ketorolac Injections for Musculoskeletal Conditions: A Narrative Review
Clin Med Res. 2024 Mar;22(1):19-27. doi: 10.3121/cmr.2024.1847.ABSTRACTMusculoskeletal conditions of the upper and lower extremities are commonly treated with corticosteroid injections. Ketorolac, a parenteral nonsteroidal anti-inflammatory drug, represents an alternative injectant for common shoulder, hip, and knee conditions. A review of the current literature was conducted on the efficacy of ketorolac injection in musculoskeletal diseases. Several studies support the use and efficacy of ketorolac injection in subacromial bursitis, adhesive capsulitis, and hip and knee osteoarthritis. Given the systemic effects of glucoc...
Source: Clinical Medicine and Research - April 12, 2024 Category: General Medicine Authors: John Kiel Andres I Applewhite Tais G O Bertasi Raphael A O Bertasi LaRae L Seemann Lorena M C Costa Haytham Helmi George G A Pujalte Source Type: research

Ketorolac Injections for Musculoskeletal Conditions: A Narrative Review
Clin Med Res. 2024 Mar;22(1):19-27. doi: 10.3121/cmr.2024.1847.ABSTRACTMusculoskeletal conditions of the upper and lower extremities are commonly treated with corticosteroid injections. Ketorolac, a parenteral nonsteroidal anti-inflammatory drug, represents an alternative injectant for common shoulder, hip, and knee conditions. A review of the current literature was conducted on the efficacy of ketorolac injection in musculoskeletal diseases. Several studies support the use and efficacy of ketorolac injection in subacromial bursitis, adhesive capsulitis, and hip and knee osteoarthritis. Given the systemic effects of glucoc...
Source: Clinical Medicine and Research - April 12, 2024 Category: General Medicine Authors: John Kiel Andres I Applewhite Tais G O Bertasi Raphael A O Bertasi LaRae L Seemann Lorena M C Costa Haytham Helmi George G A Pujalte Source Type: research

Ketorolac Injections for Musculoskeletal Conditions: A Narrative Review
Clin Med Res. 2024 Mar;22(1):19-27. doi: 10.3121/cmr.2024.1847.ABSTRACTMusculoskeletal conditions of the upper and lower extremities are commonly treated with corticosteroid injections. Ketorolac, a parenteral nonsteroidal anti-inflammatory drug, represents an alternative injectant for common shoulder, hip, and knee conditions. A review of the current literature was conducted on the efficacy of ketorolac injection in musculoskeletal diseases. Several studies support the use and efficacy of ketorolac injection in subacromial bursitis, adhesive capsulitis, and hip and knee osteoarthritis. Given the systemic effects of glucoc...
Source: Clinical Medicine and Research - April 12, 2024 Category: General Medicine Authors: John Kiel Andres I Applewhite Tais G O Bertasi Raphael A O Bertasi LaRae L Seemann Lorena M C Costa Haytham Helmi George G A Pujalte Source Type: research