Bausch Health's BRYHALI(TM) (halobetasol propionate) Lotion, 0.01%, Receives Tentative FDA Approval For Plaque Psoriasis In Adults
In Clinical Trials, BRYHALI Lotion Demonstrated Significant Treatment Success Over Vehicle as Early as Week Two, Which Continued Through Week 12 (Four Weeks Post Treatment)1 New Corticosteroid Lotion Formulation with Safety Proven for Up to Eight Weeks... Biopharmaceuticals, Dermatology, FDA Bausch Health, BRYHALI, halobetasol, Plaque Psoriasis, Psoriasis (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - October 8, 2018 Category: Pharmaceuticals Source Type: news

Rituximab Over Tacrolimus in Steroid-Dependent Nephrotic Syndrome? Rituximab Over Tacrolimus in Steroid-Dependent Nephrotic Syndrome?
Dr Desai reviews recent trials comparing steroid-sparing agents used to treat corticosteroid-dependent children with nephrotic syndrome.Medscape Nephrology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 8, 2018 Category: Consumer Health News Tags: Nephrology Viewpoint Source Type: news

Disruption in combination inhaled corticosteroid therapy may lead to an increased rate of costly exacerbations and hospitalizations for Medicare patients
(American College of Chest Physicians) Disruption of the refill of patients' regular combination inhaled corticosteroid therapy brand may have impacted symptoms and disease control and potentially lead to an increased rate of costly exacerbations and hospitalizations. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 4, 2018 Category: International Medicine & Public Health Source Type: news

Implant may improve treatment of diabetic macular oedema
Patients with advanced diabetic macular oedema show improved disease outcomes, including a reduction in central retinal thickness, when treated with a corticosteroid implant, according to research published at the Euretina 2018 meeting.Healio (Source: Society for Endocrinology)
Source: Society for Endocrinology - October 1, 2018 Category: Endocrinology Source Type: news

Corticosteroid therapy for sepsis: a clinical practice guideline
This rapid recommendation looks at whether corticosteroids reduce death or improve recovery in people with sepsis or septic shock. The panel make a weak recommendation to give corticosteroids to people with all types and severity of sepsis, based on new evidence. Because they are not certain that they are beneficial, it is also reasonable not to prescribe them. The authors state that patients'values and preferences may guide this decision-making process. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 28, 2018 Category: Consumer Health News Source Type: news

Inhaled Steroids Increase Risk of Nontuberculous Mycobacteria Lung Infections
When using inhaled corticosteroids for the treatment of asthma, COPD, and other airways disease, authors of a new study warn to proceed with caution.   (Source: ConsultantLive)
Source: ConsultantLive - September 27, 2018 Category: Internal Medicine Authors: Mark L. Fuerst Tags: Asthma Source Type: news

Study reveals a promising alternative to corticosteroids in acute renal failure treatment
(Funda ç ã o de Amparo à Pesquisa do Estado de S ã o Paulo) In search of an option for the drug known for causing several side effects, scientists describe the anti-inflammatory properties of protein galectin-1 in tests with rats involving ischemia-reperfusion scenarios. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 20, 2018 Category: International Medicine & Public Health Source Type: news

A natural chemical compound found in natto and cocoa beans found to alleviate airway inflammation
(Natural News) An animal study demonstrated the ability of ligustrazine to alleviate airway inflammation in mice with neutrophilic asthma. Found in cocoa beans and natto, the chemical compound outperformed a corticosteroid drug when it came to alleviating the inflammation caused by this type of asthma. The animal trial was supported by the Shandong University. Its findings were published in the Chinese... (Source: NaturalNews.com)
Source: NaturalNews.com - September 19, 2018 Category: Consumer Health News Source Type: news

What Type of Conservative Treatments Can Help for Plantar Fasciitis?
Discussion The plantar fascia consists of 3 bands of dense connective tissue that originates in the medical calcaneal tubercle and inserts into the base of each of the 5 proximal phalyanxes in a fan-shaped distribution. It acts as a shock absorber and reinforces the medial longitudinal arch as the foot undergoes forward propulsion. The -itis in plantar fasciitis (PF) is a misnomer as it is not an acute inflammation but is a chronic degenerative process involving the plantar fascia aponeurosis of the foot usually at the medial tubercle of the calcaneous. Repetitive strain seems to cause microtearing which then causes a repa...
Source: PediatricEducation.org - September 17, 2018 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Inhaled corticosteroids linked to higher infection risk
People using ICS at much greater risk of developing non-TB mycobacteria lung infections Related items fromOnMedica Adjuvanted trivalent flu vaccine best option for over-65s Macrolide antibiotics improve symptoms in bronchiectasis Antibiotics should be restricted for COPD, says NICE Pneumonia guidelines might raise death rate More action needed to treat TB (Source: OnMedica Latest News)
Source: OnMedica Latest News - September 14, 2018 Category: UK Health Source Type: news

Lymphocytic Colitis Responds Rapidly to Budesonide (CME/CE)
(MedPage Today) -- Corticosteroid outperformed mesalamine and placebo in small randomized trial (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - September 13, 2018 Category: Gastroenterology Source Type: news

Corticosteroids at Time of PD-L1 Blockade May Reduce Efficacy in NSCLC
Taking corticosteroids at the time of treatment initiation with PD-L1 inhibitors may lead to inferior outcomes in patients with non –small-cell lung cancer. (Source: CancerNetwork)
Source: CancerNetwork - September 10, 2018 Category: Cancer & Oncology Authors: John Schieszer Source Type: news

Tezepelumab granted Breakthrough Therapy Designation by US FDA
AstraZeneca and its partner Amgen Inc. (Amgen) today announced that the US Food and Drug Administration (FDA) has granted Breakthrough Therapy Designation for tezepelumab in patients with severe asthma, without an eosinophilic phenotype, who are receiving inhaled corticosteroids/long-acting beta2-agonists with or without oral corticosteroids and additional asthma controllers. (Source: World Pharma News)
Source: World Pharma News - September 7, 2018 Category: Pharmaceuticals Tags: Featured AstraZeneca Business and Industry Source Type: news

Eczema treatment: Apply this type of oil to sore and itchy skin for instant relief
ECZEMA treatments recommended by GPs usually come in the form of moisturisers and topical corticosteroid creams. But some health experts recommend those looking for a natural remedy to sooth their sore and itchy skin with a particular type of oil. (Source: Daily Express - Health)
Source: Daily Express - Health - September 4, 2018 Category: Consumer Health News Source Type: news

FDA Addresses Severe Lack of Pediatric Devices
To address the scarcity of medical devices that are designed specifically for the pediatric population, FDA convened a public meeting and workshop August 13–14, 2018 to delve into the financial, regulatory, and design constraints associated with this challenging endeavor.[1] Speakers at the workshop included FDA regulators, sponsors, clinicians, and members of the American Academy of Pediatrics. The prevailing message from the workshop was that while there are many barriers to the development of pediatric-specific devices, FDA and community in attendance is committed to developing innovative pathways and ...
Source: MDDI - August 30, 2018 Category: Medical Devices Authors: Jessie Huisinga, PhD and Leah Taylor, MS Tags: Regulatory and Compliance Source Type: news

Kala Pharma wins FDA nod for twice-daily ocular corticosteroid
The FDA has approved Kala Pharmaceuticals’ (NASDAQ:KALA) Inveltys to treat post-operative inflammation and pain following ocular surgery. Inveltys is the first twice-daily (BID) ocular corticosteroid approved for this indication, according to the Waltham, Mass. company. While corticosteroids are used following ocular surgery to control inflammation and pain, physicians prescribe ocular steroids to achieve a rapid reduction of inflammation and to promote healing. All other ocular steroids are only approved for four-times-a-day dosing. Get the full story on our sister site, Drug Delivery Business. The po...
Source: Mass Device - August 24, 2018 Category: Medical Devices Authors: Nancy Crotti Tags: Blog Clinical Trials Food & Drug Administration (FDA) Optical/Ophthalmic Pain Management Pharma Pharmaceuticals Kala Pharmaceuticals Source Type: news

Arthritis Linked with Preterm Delivery
(MedPage Today) -- Active disease and corticosteroid exposure implicated (Source: MedPage Today OB/GYN)
Source: MedPage Today OB/GYN - August 22, 2018 Category: OBGYN Source Type: news

Mount Sinai receives NIH Grant to study use of inhaled corticosteroids for sickle cell treatment
(The Mount Sinai Hospital / Mount Sinai School of Medicine) The Departments of Emergency Medicine and Hematology at the Icahn School of Medicine at Mount Sinai have been awarded a $4 million grant from the National Institutes of Health toward further study of inhaled corticosteroids to treat sickle cell disease (SCD) in individuals who do not have asthma. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 13, 2018 Category: International Medicine & Public Health Source Type: news

Asthma inhalers found to make women fat while increasing risk of heart disease
(Natural News) Corticosteroids in asthma inhalers could make women fat and increase the risk of metabolic syndrome, a recent study found. Corticosteroids are widely-used anti-inflammatory agents that come in many forms — such as inhalers, nasal sprays, tablets, injections and cream — and are prescribed to ease symptoms of asthma and other respiratory diseases. Metabolic... (Source: NaturalNews.com)
Source: NaturalNews.com - August 9, 2018 Category: Consumer Health News Source Type: news

FDA Panel Votes Against Recommending Mepolizumab for COPD FDA Panel Votes Against Recommending Mepolizumab for COPD
An FDA panel recommended against mepolizumab as add-on treatment to inhaled corticosteroid-based maintenance treatment in patients with COPD guided by blood eosinophil counts.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 26, 2018 Category: Consumer Health News Tags: Pulmonary Medicine News Source Type: news

Rhodococcus equi Pulmonary Infection in an Immunocompromised Patient: Case Report and Literature Review
We present a case of R. equi lung abscess in a 49-year-old immunocompromised male who was on long-term corticosteroid therapy. The patient recovered soon after he was treated with vancomycin and imipenem. The identification of R. equi is often difficult, because it closely resembles other bacterial pathogens, such as diphtheroids and Mycobacterium and Nocardia species. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - July 21, 2018 Category: Microbiology Authors: Zeti Norfidiyati Salmuna, Wan Amani Wan Abdul Azim, Azian Harun Tags: Case Report Source Type: news

Corticosteroids in Sepsis: An Updated Systematic Review and Meta-Analysis
Conclusions: In critically ill patients with sepsis, corticosteroids possibly result in a small reduction in mortality while also possibly increasing the risk of neuromuscular weakness. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - July 19, 2018 Category: Consumer Health News Source Type: news

How Common is Recurrent Kawasaki Disease?
Patient Presentation A 3.5-year-old female came to clinic with a 2-day history fever up to 101°F. The evening before she had complained of a sore throat but had no rhinorrhea, cough or rash. She was drinking reasonably well and was urinating frequently. She had been to a birthday party where an older child had had strep throat. The past medical history was positive for Kawasaki Disease diagnosed at 17 months of age and treated with intravenous immunoglobulin (IVIG) on day 6 of fever. Her echocardiograms had been negative and she was being appropriately monitored by cardiology. The family history was positive for heart...
Source: PediatricEducation.org - July 16, 2018 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Dupilumab With Topical Corticosteroids for Atopic Dermatitis Dupilumab With Topical Corticosteroids for Atopic Dermatitis
This study evaluated the efficacy of the newly approved biologic dupilumab in this difficult-to-treat population.The British Journal of Dermatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 5, 2018 Category: Consumer Health News Tags: Dermatology Journal Article Source Type: news

How a New Emphysema Device Won FDA Approval in Six Months
FDA has approved a new device intended to treat breathing difficulty associated with severe emphysema. The approval comes just two weeks after an FDA advisory panel shot down a competing technology targeting the same patient population. The agency approved Pulmonx Inc.'s Zephyr endobronchial valve through the breakthrough device designation, a pathway reserved for devices that provide for more effective treatment or diagnosis of a life-threatening or irreversibly debilitating disease or condition. Devices also must meet one of the following criteria: the device must represent a breakthrough technology; there must be no app...
Source: MDDI - July 2, 2018 Category: Medical Devices Authors: Amanda Pedersen Tags: Regulatory and Compliance Source Type: news

No Plant Oils for Cradle Cap?
Discussion During growth, plants first store their energy as carbohydrates but during ripening switch over to carbon-rich triglycerides. Triglycerides also occur in yeasts, molds and animal fats. A few higher plants store lipids in other forms. One example is the Jojoba which stores its oil as a lipid wax. Simmondsia chinensis (Jojoba) is a specialty-cultivated plant found mainly in the American Southwest and Mexican Northwest. Jojoba seed oil has> 50% of its weight as liquid wax esters that are used in personal care products and lubricants. Jojoba oil is naturally extracted from the seed or synthetically produced. Natu...
Source: PediatricEducation.org - July 2, 2018 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Corticosteroid-related adverse outcomes costly in asthma
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - July 1, 2018 Category: Drugs & Pharmacology Source Type: news

Teens with eczema may not follow prescribed treatment regimen
(Reuters Health) - Adolescents with eczema who are prescribed topical corticosteroids to ease symptoms like itching and inflammation may not use their medicines as directed, a small study suggests. (Source: Reuters: Health)
Source: Reuters: Health - June 22, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Medical News Today: What is perioral dermatitis and how is it treated?
Perioral dermatitis is a rash that affects the skin around the mouth. The cause is unknown, but research suggests that it is a reaction to the misuse of topical corticosteroids. Other triggers may include hormonal changes and allergic reactions. Learn more about perioral dermatitis and how to prevent and treat it here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - June 19, 2018 Category: Consumer Health News Tags: Dermatology Source Type: news

Immunosuppressants Linked to Lower PD Risk
(MedPage Today) -- Corticosteroids, IMDH inhibitors show strongest associations (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - June 7, 2018 Category: Neurology Source Type: news

Management of AD With Dupilumab and Topical Corticosteroids Management of AD With Dupilumab and Topical Corticosteroids
This appraisal of a recent study on the efficacy and safety of long-term therapy with dupilumab, the first USFDA approved biological treatment for moderate-to-severe AD, revealed some concerns.The British Journal of Dermatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 7, 2018 Category: Consumer Health News Tags: Dermatology Journal Article Source Type: news

Corticosteroids for Treating Sepsis
This Cochrane Review was updated in May 2018, when new feedback and a reply were added. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - June 1, 2018 Category: Consumer Health News Source Type: news

Arthritis and asthma sufferers may be up to one-third less likely to develop Parkinson's disease
Researchers from the University of Washington found people who take  corticosteroids, which are commonly prescribed for psoriasis and ulcerative colitis, are 20 percent less at risk of suffering tremors. (Source: the Mail online | Health)
Source: the Mail online | Health - May 31, 2018 Category: Consumer Health News Source Type: news

Aggressive Steroid Tx Improves Visual Outcomes in Vogt-Koyanagi-Harada Aggressive Steroid Tx Improves Visual Outcomes in Vogt-Koyanagi-Harada
Aggressive treatment beginning with pulsed intravenous corticosteroids appears to improve visual outcomes of new-onset acute Vogt-Koyanagi-Harada (VKH) disease, researchers from Japan report.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 24, 2018 Category: Consumer Health News Tags: Ophthalmology News Source Type: news

GSK Receives FDA Approval of Arnuity Ellipta for Asthma in Children From 5 Years of Age
London, UK 21 May 2018 --GSK today announced it has received approval from the US Food and Drug Administration (FDA) for the use of Arnuity Ellipta (fluticasone furoate) a once-daily inhaled corticosteroid (ICS) medicine for the maintenance... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - May 24, 2018 Category: Drugs & Pharmacology Source Type: news

Study demonstrates new treatment for severe asthma
Researchers from McMaster University and the Firestone Institute for Respiratory Health at St. Joseph's Healthcare Hamilton, together with colleagues at other partnering institutions, have developed a new method to treat severe asthma. In a study of over 200 participants with severe asthma, the new treatment was shown to have improved asthma symptoms and lung function, while reducing the need for corticosteroids by up to 70%. (Source: World Pharma News)
Source: World Pharma News - May 22, 2018 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

Study demonstrates new treatment for severe asthma
(McMaster University) Researchers from McMaster University and the Firestone Institute for Respiratory Health at St. Joseph's Healthcare Hamilton, together with colleagues at other partnering institutions, have developed a new method to treat severe asthma. In a study of over 200 participants with severe asthma, the new treatment was shown to have improved asthma symptoms and lung function, while reducing the need for corticosteroids by up to 70%. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 22, 2018 Category: International Medicine & Public Health Source Type: news

Inhaled Steroids in Childhood Asthma: Does Dose Matter? Inhaled Steroids in Childhood Asthma: Does Dose Matter?
Can increasing a child's inhaled corticosteroid dose at the first hint of an asthma attack head off a worsening exacerbation?Medscape Pediatrics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 21, 2018 Category: Consumer Health News Tags: Pediatrics Viewpoint Source Type: news

Inhaled Corticosteroids in COPD Raises Fracture Risk
No abstract available (Source: Lippincott's Bone and Joint Newsletter)
Source: Lippincott's Bone and Joint Newsletter - May 16, 2018 Category: Orthopaedics Tags: CME Article Source Type: news

Medical News Today: What to know about angiolipoma
Angiolipoma is a small, soft tumor made up of fatty cells and blood vessels. They are often found on the forearm, and multiple lumps may occur at the same time. Angiolipoma is not cancerous, and treatment or removal is often successful with minor surgery or corticosteroid injections. Learn more about angiolipoma here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 16, 2018 Category: Consumer Health News Tags: Dermatology Source Type: news

Self-harm behaviour is modulated by stress hormone
According to a study, published in theJournal of Neuroscience, corticosteroid regulates the brain circuitry associated with self-harming behaviour, in a rat model.Medical Xpress (Source: Society for Endocrinology)
Source: Society for Endocrinology - May 15, 2018 Category: Endocrinology Source Type: news

Corticosteroid Use Decreases Voriconazole Concentration
Wed, 05/09/2018 - 13:17News blog (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - May 9, 2018 Category: Respiratory Medicine Authors: ROrritt Source Type: news

High-Dose Corticosteroid Treatment and Mortality in ARDS High-Dose Corticosteroid Treatment and Mortality in ARDS
Past studies have shown that high-dose corticosteroid therapy did not improve the outcomes of patients with ARDS -- but is it time to revisit the issue?BMC Pulmonary Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 9, 2018 Category: Consumer Health News Tags: Pulmonary Medicine Journal Article Source Type: news

Use of Systemic Corticosteroids for Atopic Dermatitis Use of Systemic Corticosteroids for Atopic Dermatitis
Despite recommendations against the use of systemic corticosteroids for atopic dermatitis, their use remains widespread. Under what limited circumstances is it appropriate to use them?The British Journal of Dermatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 3, 2018 Category: Consumer Health News Tags: Dermatology Journal Article Source Type: news

Ingestion of caustic substances: an analysis of the safety and benefit of a less aggressive protocol - Ripoll Trujillo N, Mart ínez Sánchez L, Habimana Jordana A, Trenchs Sainz de La Maza V, Vila Miravet V, Luaces Cubells C.
INTRODUCTION: The ingestion of a caustic agent is the most common cause of admission after being in contact with a domestic product. A group of patients could be considered low risk and not require aggressive procedures such a corticosteroid administration... (Source: SafetyLit)
Source: SafetyLit - April 23, 2018 Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news

Oral and IV Corticosteroids Equivalent for Optic Neuritis Oral and IV Corticosteroids Equivalent for Optic Neuritis
Dr Laurie Barclay on new data comparing the efficacy of different corticosteroid administration routes in a condition that often presents alongside MS.Medscape Neurology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 5, 2018 Category: Consumer Health News Tags: Neurology & Neurosurgery Viewpoint Source Type: news

Community Collaboration Improves Asthma Control Community Collaboration Improves Asthma Control
The AIR Louisville Collaborative's pairing of data analysis on corticosteroid use with a patient asthma management app led to less rescue inhaler use and more symptom-free days.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 4, 2018 Category: Consumer Health News Tags: Pulmonary Medicine News Source Type: news

Medical News Today: How to get rid of an allergic reaction on the face
An allergic reaction on the face can cause symptoms, such as red, raised bumps, swollen lips, and wheezing. They are often caused by beauty products or hay fever. Treatments include antihistamines, cool compresses, and corticosteroid creams. Reactions can be prevented by avoiding allergens and taking antihistamines. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 31, 2018 Category: Consumer Health News Tags: Allergy Source Type: news

The stressed brain of humans and rodents - Jo ëls M, Karst H, Sarabdjitsingh RA.
After stress, the brain is exposed to waves of stress mediators, including corticosterone (in rodents) and cortisol (in humans). Corticosteroid hormones affect neuronal physiology in two time-domains: rapid, non-genomic actions primarily via mineralocortic... (Source: SafetyLit)
Source: SafetyLit - March 28, 2018 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Medication Exposure and Risk of Recurrent C. diff Infection Medication Exposure and Risk of Recurrent C. diff Infection
How does exposure to medications such as antibiotics, corticosteroids, and acid-reducers impact the risk of recurrent C. difficile infection? Does risk differ according to living environment?Journal of the American Geriatrics Society (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 28, 2018 Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news