Corticosteroids in Sepsis: An Updated Systematic Review and Meta-Analysis
Conclusions: In critically ill patients with sepsis, corticosteroids possibly result in a small reduction in mortality while also possibly increasing the risk of neuromuscular weakness. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - July 19, 2018 Category: Consumer Health News Source Type: news

How Common is Recurrent Kawasaki Disease?
Patient Presentation A 3.5-year-old female came to clinic with a 2-day history fever up to 101°F. The evening before she had complained of a sore throat but had no rhinorrhea, cough or rash. She was drinking reasonably well and was urinating frequently. She had been to a birthday party where an older child had had strep throat. The past medical history was positive for Kawasaki Disease diagnosed at 17 months of age and treated with intravenous immunoglobulin (IVIG) on day 6 of fever. Her echocardiograms had been negative and she was being appropriately monitored by cardiology. The family history was positive for heart...
Source: PediatricEducation.org - July 16, 2018 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Dupilumab With Topical Corticosteroids for Atopic Dermatitis Dupilumab With Topical Corticosteroids for Atopic Dermatitis
This study evaluated the efficacy of the newly approved biologic dupilumab in this difficult-to-treat population.The British Journal of Dermatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 5, 2018 Category: Consumer Health News Tags: Dermatology Journal Article Source Type: news

How a New Emphysema Device Won FDA Approval in Six Months
FDA has approved a new device intended to treat breathing difficulty associated with severe emphysema. The approval comes just two weeks after an FDA advisory panel shot down a competing technology targeting the same patient population. The agency approved Pulmonx Inc.'s Zephyr endobronchial valve through the breakthrough device designation, a pathway reserved for devices that provide for more effective treatment or diagnosis of a life-threatening or irreversibly debilitating disease or condition. Devices also must meet one of the following criteria: the device must represent a breakthrough technology; there must be no app...
Source: MDDI - July 2, 2018 Category: Medical Devices Authors: Amanda Pedersen Tags: Regulatory and Compliance Source Type: news

No Plant Oils for Cradle Cap?
Discussion During growth, plants first store their energy as carbohydrates but during ripening switch over to carbon-rich triglycerides. Triglycerides also occur in yeasts, molds and animal fats. A few higher plants store lipids in other forms. One example is the Jojoba which stores its oil as a lipid wax. Simmondsia chinensis (Jojoba) is a specialty-cultivated plant found mainly in the American Southwest and Mexican Northwest. Jojoba seed oil has> 50% of its weight as liquid wax esters that are used in personal care products and lubricants. Jojoba oil is naturally extracted from the seed or synthetically produced. Natu...
Source: PediatricEducation.org - July 2, 2018 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Teens with eczema may not follow prescribed treatment regimen
(Reuters Health) - Adolescents with eczema who are prescribed topical corticosteroids to ease symptoms like itching and inflammation may not use their medicines as directed, a small study suggests. (Source: Reuters: Health)
Source: Reuters: Health - June 22, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Medical News Today: What is perioral dermatitis and how is it treated?
Perioral dermatitis is a rash that affects the skin around the mouth. The cause is unknown, but research suggests that it is a reaction to the misuse of topical corticosteroids. Other triggers may include hormonal changes and allergic reactions. Learn more about perioral dermatitis and how to prevent and treat it here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - June 19, 2018 Category: Consumer Health News Tags: Dermatology Source Type: news

Immunosuppressants Linked to Lower PD Risk
(MedPage Today) -- Corticosteroids, IMDH inhibitors show strongest associations (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - June 7, 2018 Category: Neurology Source Type: news

Management of AD With Dupilumab and Topical Corticosteroids Management of AD With Dupilumab and Topical Corticosteroids
This appraisal of a recent study on the efficacy and safety of long-term therapy with dupilumab, the first USFDA approved biological treatment for moderate-to-severe AD, revealed some concerns.The British Journal of Dermatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 7, 2018 Category: Consumer Health News Tags: Dermatology Journal Article Source Type: news

Corticosteroids for Treating Sepsis
This Cochrane Review was updated in May 2018, when new feedback and a reply were added. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - June 1, 2018 Category: Consumer Health News Source Type: news

Arthritis and asthma sufferers may be up to one-third less likely to develop Parkinson's disease
Researchers from the University of Washington found people who take  corticosteroids, which are commonly prescribed for psoriasis and ulcerative colitis, are 20 percent less at risk of suffering tremors. (Source: the Mail online | Health)
Source: the Mail online | Health - May 31, 2018 Category: Consumer Health News Source Type: news

Aggressive Steroid Tx Improves Visual Outcomes in Vogt-Koyanagi-Harada Aggressive Steroid Tx Improves Visual Outcomes in Vogt-Koyanagi-Harada
Aggressive treatment beginning with pulsed intravenous corticosteroids appears to improve visual outcomes of new-onset acute Vogt-Koyanagi-Harada (VKH) disease, researchers from Japan report.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 24, 2018 Category: Consumer Health News Tags: Ophthalmology News Source Type: news

GSK Receives FDA Approval of Arnuity Ellipta for Asthma in Children From 5 Years of Age
London, UK 21 May 2018 --GSK today announced it has received approval from the US Food and Drug Administration (FDA) for the use of Arnuity Ellipta (fluticasone furoate) a once-daily inhaled corticosteroid (ICS) medicine for the maintenance... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - May 24, 2018 Category: Drugs & Pharmacology Source Type: news

Study demonstrates new treatment for severe asthma
Researchers from McMaster University and the Firestone Institute for Respiratory Health at St. Joseph's Healthcare Hamilton, together with colleagues at other partnering institutions, have developed a new method to treat severe asthma. In a study of over 200 participants with severe asthma, the new treatment was shown to have improved asthma symptoms and lung function, while reducing the need for corticosteroids by up to 70%. (Source: World Pharma News)
Source: World Pharma News - May 22, 2018 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

Study demonstrates new treatment for severe asthma
(McMaster University) Researchers from McMaster University and the Firestone Institute for Respiratory Health at St. Joseph's Healthcare Hamilton, together with colleagues at other partnering institutions, have developed a new method to treat severe asthma. In a study of over 200 participants with severe asthma, the new treatment was shown to have improved asthma symptoms and lung function, while reducing the need for corticosteroids by up to 70%. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 22, 2018 Category: International Medicine & Public Health Source Type: news

Inhaled Steroids in Childhood Asthma: Does Dose Matter? Inhaled Steroids in Childhood Asthma: Does Dose Matter?
Can increasing a child's inhaled corticosteroid dose at the first hint of an asthma attack head off a worsening exacerbation?Medscape Pediatrics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 21, 2018 Category: Consumer Health News Tags: Pediatrics Viewpoint Source Type: news

Inhaled Corticosteroids in COPD Raises Fracture Risk
No abstract available (Source: Lippincott's Bone and Joint Newsletter)
Source: Lippincott's Bone and Joint Newsletter - May 16, 2018 Category: Orthopaedics Tags: CME Article Source Type: news

Medical News Today: What to know about angiolipoma
Angiolipoma is a small, soft tumor made up of fatty cells and blood vessels. They are often found on the forearm, and multiple lumps may occur at the same time. Angiolipoma is not cancerous, and treatment or removal is often successful with minor surgery or corticosteroid injections. Learn more about angiolipoma here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 16, 2018 Category: Consumer Health News Tags: Dermatology Source Type: news

Self-harm behaviour is modulated by stress hormone
According to a study, published in theJournal of Neuroscience, corticosteroid regulates the brain circuitry associated with self-harming behaviour, in a rat model.Medical Xpress (Source: Society for Endocrinology)
Source: Society for Endocrinology - May 15, 2018 Category: Endocrinology Source Type: news

Corticosteroid Use Decreases Voriconazole Concentration
Wed, 05/09/2018 - 13:17News blog (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - May 9, 2018 Category: Respiratory Medicine Authors: ROrritt Source Type: news

High-Dose Corticosteroid Treatment and Mortality in ARDS High-Dose Corticosteroid Treatment and Mortality in ARDS
Past studies have shown that high-dose corticosteroid therapy did not improve the outcomes of patients with ARDS -- but is it time to revisit the issue?BMC Pulmonary Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 9, 2018 Category: Consumer Health News Tags: Pulmonary Medicine Journal Article Source Type: news

Use of Systemic Corticosteroids for Atopic Dermatitis Use of Systemic Corticosteroids for Atopic Dermatitis
Despite recommendations against the use of systemic corticosteroids for atopic dermatitis, their use remains widespread. Under what limited circumstances is it appropriate to use them?The British Journal of Dermatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 3, 2018 Category: Consumer Health News Tags: Dermatology Journal Article Source Type: news

Ingestion of caustic substances: an analysis of the safety and benefit of a less aggressive protocol - Ripoll Trujillo N, Mart ínez Sánchez L, Habimana Jordana A, Trenchs Sainz de La Maza V, Vila Miravet V, Luaces Cubells C.
INTRODUCTION: The ingestion of a caustic agent is the most common cause of admission after being in contact with a domestic product. A group of patients could be considered low risk and not require aggressive procedures such a corticosteroid administration... (Source: SafetyLit)
Source: SafetyLit - April 23, 2018 Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news

Oral and IV Corticosteroids Equivalent for Optic Neuritis Oral and IV Corticosteroids Equivalent for Optic Neuritis
Dr Laurie Barclay on new data comparing the efficacy of different corticosteroid administration routes in a condition that often presents alongside MS.Medscape Neurology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 5, 2018 Category: Consumer Health News Tags: Neurology & Neurosurgery Viewpoint Source Type: news

Community Collaboration Improves Asthma Control Community Collaboration Improves Asthma Control
The AIR Louisville Collaborative's pairing of data analysis on corticosteroid use with a patient asthma management app led to less rescue inhaler use and more symptom-free days.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 4, 2018 Category: Consumer Health News Tags: Pulmonary Medicine News Source Type: news

Medical News Today: How to get rid of an allergic reaction on the face
An allergic reaction on the face can cause symptoms, such as red, raised bumps, swollen lips, and wheezing. They are often caused by beauty products or hay fever. Treatments include antihistamines, cool compresses, and corticosteroid creams. Reactions can be prevented by avoiding allergens and taking antihistamines. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 31, 2018 Category: Consumer Health News Tags: Allergy Source Type: news

The stressed brain of humans and rodents - Jo ëls M, Karst H, Sarabdjitsingh RA.
After stress, the brain is exposed to waves of stress mediators, including corticosterone (in rodents) and cortisol (in humans). Corticosteroid hormones affect neuronal physiology in two time-domains: rapid, non-genomic actions primarily via mineralocortic... (Source: SafetyLit)
Source: SafetyLit - March 28, 2018 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Medication Exposure and Risk of Recurrent C. diff Infection Medication Exposure and Risk of Recurrent C. diff Infection
How does exposure to medications such as antibiotics, corticosteroids, and acid-reducers impact the risk of recurrent C. difficile infection? Does risk differ according to living environment?Journal of the American Geriatrics Society (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 28, 2018 Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news

Ocular nonsuicidal self-injury in a teenager - Comacchio F, Ricca M, Martini G, Cecchin V, Zannin ME.
A 14-year-old male teen presented with unilateral episcleritis, unresponsive to topical and systemic corticosteroid therapy, without a history of ocular trauma or evidence for systemic diseases. The presence of foreign bodies in the conjunctival mucus of t... (Source: SafetyLit)
Source: SafetyLit - March 26, 2018 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Antihistamines vs. Corticosteroids
Title: Antihistamines vs. CorticosteroidsCategory: MedicationsCreated: 3/23/2018 12:00:00 AMLast Editorial Review: 3/23/2018 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - March 23, 2018 Category: Drugs & Pharmacology Source Type: news

5 Reasons Your Allergies Are Worse at Night
This article originally appeared on Health.com (Source: TIME: Health)
Source: TIME: Health - March 21, 2018 Category: Consumer Health News Authors: Sarah Klein / Health.com Tags: Uncategorized allergies healthytime onetime Source Type: news

Reviews Reveal Benefits of LAMAs, LABAs, and SMART in Asthma Reviews Reveal Benefits of LAMAs, LABAs, and SMART in Asthma
Two systematic reviews found LAMAs effective but not superior to LABAs as adjunct to inhaled corticosteroids, and single maintenance and reliever therapy had greater benefit within limits.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 20, 2018 Category: Consumer Health News Tags: Pulmonary Medicine News Source Type: news

Genetic variant discovery to help asthma sufferers
(University of Liverpool) Research from the University of Liverpool, published in Lancet Respiratory Medicine, identifies a genetic variant that could improve the safety and effectiveness of corticosteroids, drugs that are used to treat a range of common and rare conditions including asthma, and chronic obstructive pulmonary disease (COPD). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 16, 2018 Category: International Medicine & Public Health Source Type: news

Predicting Corticosteroid Response in Asthmatic Children Predicting Corticosteroid Response in Asthmatic Children
A newly developed tool may help predict the treatment response to inhaled corticosteroids among children with asthma.BMC Pulmonary Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 14, 2018 Category: Consumer Health News Tags: Pulmonary Medicine Journal Article Source Type: news

How to Prevent Asthma Exacerbations: Is More ICS Better?
Two studies look at the effect of increasing the dose of inhaled corticosteroids 4 and 5 times to abort asthma deterioration. The results may surprise you.   (Source: ConsultantLive)
Source: ConsultantLive - March 14, 2018 Category: Internal Medicine Authors: Veronica Hackethal, MD Tags: Asthma Source Type: news

Alternative treatment for allergic reaction to substance discovered
Louisiana State researchers have found a new treatment for the allergic reaction to substances instead of corticosteroids. (Source: Health News - UPI.com)
Source: Health News - UPI.com - March 8, 2018 Category: Consumer Health News Source Type: news

LSU Health New Orleans research discovers new Rx for allergic contact dermatitis
(Louisiana State University Health Sciences Center) Research led by Nicolas Bazan, MD, PhD, Boyd Professor and Director of the Neuroscience Center of Excellence at LSU Health New Orleans School of Medicine, has found a promising new treatment for allergic contact dermatitis that offers an alternative to corticosteroids and their possible side effects. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 8, 2018 Category: International Medicine & Public Health Source Type: news

Inhaled Triple Therapy Reduces COPD Exacerbations Inhaled Triple Therapy Reduces COPD Exacerbations
Inhaled triple therapy, consisting of inhaled corticosteroid, long-acting muscarinic antagonist, and long-acting beta2-agonist, reduces exacerbations in patients with severe chronic obstructive pulmonary disease (COPD), compared with dual bronchodilator therapy, according to results from the TRIBUTE trial.Reuters Health Information (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - March 5, 2018 Category: Allergy & Immunology Tags: Pulmonary Medicine News Source Type: news

Clearside Biomedical shares soar after eye drug succeeds in Ph3 trial
Clearside Biomedical (NSDQ:CLSD) shares soared more than 50% in pre-market activity today after the company reported that its suprachoroidal eye drug succeeded in a pivotal Phase III trial of patients with macular edema associated with non-infectious uveitis. The company’s drug, CLS-TA, is a proprietary suspension of a corticosteroid, triamcinolone acetonide, designed to be administered to the back of the eye via the suprachoroidal space. Get the full story at our sister site, Drug Delivery Business News. The post Clearside Biomedical shares soar after eye drug succeeds in Ph3 trial appeared first on MassDevice....
Source: Mass Device - March 5, 2018 Category: Medical Devices Authors: Sarah Faulkner Tags: Clinical Trials Drug-Device Combinations Optical/Ophthalmic Pharmaceuticals Wall Street Beat Clearside Biomedical Source Type: news

Many Adults Get Systemic Steroids for Acute Respiratory Tract Illnesses Many Adults Get Systemic Steroids for Acute Respiratory Tract Illnesses
Many adults with acute respiratory tract illnesses (ARTIs) receive corticosteroid injections or prescriptions, despite clinical practice guidelines that recommend otherwise, according to a retrospective study.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 27, 2018 Category: Consumer Health News Tags: Medscape Today News Source Type: news

Long - Term Inhaled Corticosteroid Use May Raise Fracture Risk
Long - term inhaled corticosteroid use for COPD tied to small increased risk of hip, upper extremity fracture (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - February 16, 2018 Category: Respiratory Medicine Tags: Internal Medicine, Orthopedics, Pharmacy, Pulmonology, Journal, Source Type: news

Discovery the phenomenon of polymorphism in the atomic structure of the methylprednisolone aceponate
(Lobachevsky University) UNN researchers have discovered the phenomenon of polymorphism in the atomic structure of the methylprednisolone aceponate crystal. They managed to synthesize a single crystal of corticosteroid hormone methylprednisolone aceponate, which was of a sufficient size for X-ray diffraction studies. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 15, 2018 Category: International Medicine & Public Health Source Type: news

GSK seeks expanded label for Trelegy Ellipta inhaler in EU
GlaxoSmithKline (NYSE:GSK) and Innoviva (NSDQ:INVA) have submitted data to the European Medicines Agency in the hopes of expanding the label for its once-daily, triple combination inhaler, Trelegy Ellipta. The drug-device combo was approved in Europe in November last year as a maintenance treatment for adult patients with moderate to severe chronic obstructive pulmonary disease who are not adequately treated by a inhaled corticosteroid combined with a long-acting beta-adrenergic agonist. GSK and Innoviva hope that data from its Impact trial will support the product’s use in a broader populati...
Source: Mass Device - February 14, 2018 Category: Medical Devices Authors: Sarah Faulkner Tags: Clinical Trials Drug-Device Combinations Pharmaceuticals Respiratory Wall Street Beat GlaxoSmithKline plc Innoviva Source Type: news

Widely Used COPD Meds Tied to Increased Fracture Risk
TUESDAY, Feb. 13, 2018 -- Many patients with chronic obstructive pulmonary disease (COPD) are placed on powerful inhaled corticosteroid therapy to ease symptoms. But new research suggests the treatment might raise their odds for bone... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - February 13, 2018 Category: General Medicine Source Type: news

Teva launches breath-activated asthma aerosol in U.S.
Teva Pharmaceuticals (NYSE:TEVA) has launched its Qvar RediHaler inhalation aerosol in the U.S., marking the first time a breath-actuated inhaled corticosteroid is available for asthma patients as a prophylactic therapy. In contrast to traditional metered-dose inhalers, Teva’s Qvar RediHaler sends medication into the user’s lungs as they inhale. This feature eliminates the need for hand-breath coordination, according to Teva. Get the full story at our sister site, Drug Delivery Business News. The post Teva launches breath-activated asthma aerosol in U.S. appeared first on MassDevice. (Source: Mass Device)
Source: Mass Device - February 12, 2018 Category: Medical Devices Authors: Sarah Faulkner Tags: Drug-Device Combinations Pharmaceuticals Respiratory Wall Street Beat Teva Pharmaceuticals Source Type: news

Probiotics May Improve Pediatric AD Symptoms
(MedPage Today) -- Probiotics may also reduce need for topical corticosteroids (Source: MedPage Today Pediatrics)
Source: MedPage Today Pediatrics - February 11, 2018 Category: Pediatrics Source Type: news

Study: Long-term use of inhaled corticosteroids may heighten risk of bone fractures in COPD patients
Researchers reported this month that in men and women with chronic obstructive pulmonary disease, long-term use of inhaled corticosteroids may be linked to an increased risk of bone fractures. Previous research has shown that the inhaled drugs, used to treat COPD, impact bone mineral density based on the dose of the corticosteroid, especially in post-menopausal women. Get the full story at our sister site, Drug Delivery Business News. The post Study: Long-term use of inhaled corticosteroids may heighten risk of bone fractures in COPD patients appeared first on MassDevice. (Source: Mass Device)
Source: Mass Device - February 6, 2018 Category: Medical Devices Authors: Sarah Faulkner Tags: Drug-Device Combinations Pharmaceuticals Research & Development Respiratory Novartis Source Type: news

Long-term usage of inhaled corticosteroids may increase risk of bone fractures in patients with COPD
(American College of Chest Physicians) A study published in the February journal CHEST ® suggests long-term inhaled corticosteroids (ICS) in patients with COPD may increase risk of bone fractures in both men and women. Previous studies have suggested that ICS negatively impacts bone mineral density in a dose-dependent fashion, particularly affecting postmenopausal women, but it has been unclear whether these effects translate to bone fractures. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 5, 2018 Category: International Medicine & Public Health Source Type: news

Do Corticosteroids Improve Diabetic Macular Edema Outcomes? Do Corticosteroids Improve Diabetic Macular Edema Outcomes?
Drs Matt Starr and Sophie Bakri on a randomized trial studying the value of adding intravitreal dexamethasone to anti-VEGF therapy.Medscape Ophthalmology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 30, 2018 Category: Consumer Health News Tags: Ophthalmology Viewpoint Source Type: news

Blood Eosinophil Counts Predict COPD Exacerbations, Response to Steroids Blood Eosinophil Counts Predict COPD Exacerbations, Response to Steroids
Higher blood eosinophil counts are associated with an increased risk of exacerbation and a better chance of responding to inhaled corticosteroids (ICS) in patients with chronic obstructive pulmonary disease (COPD), according to a post hoc analysis.Reuters Health Information (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 29, 2018 Category: Consumer Health News Tags: Pulmonary Medicine News Source Type: news