Death Certification: Errors and Interventions.
CONCLUSION: This study reaffirms the importance of autopsy and autopsy pathologists in ensuring accurate and complete death certification. It also suggests that death certification errors may be more frequent than previously reported. We propose a method by which death certification errors can be classified in terms of increasing severity. By understanding the types of errors occurring on death certificates, academic institutions can work to improve certification accuracy. Better clinician education, coordination with autopsy pathologists, and implementation of a systematic approach to ensuring concordance of death certifi...
Source: Clinical Medicine and Research - October 9, 2019 Category: General Medicine Authors: Schuppener LM, Olson K, Brooks EG Tags: Clin Med Res Source Type: research

Beyond Hemoglobin: When and How to Work Up Possible Polycythemia Vera.
CONCLUSIONS: Readily accessible clinical and laboratory data can assist in considering a PV workup, and a possible diagnostic algorithm is presented. These preliminary findings warrant larger studies to develop a more formal PV-risk scoring system with optimal cutoffs and weighting. PMID: 31582417 [PubMed - as supplied by publisher] (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - October 3, 2019 Category: General Medicine Authors: Shaw G, Berg R Tags: Clin Med Res Source Type: research

First Report of Retroperitoneal Mucinous Cystadenoma in a Patient with Hirsutism.
Abstract Primary retroperitoneal mucinous cystadenomas (PRMC) are rare benign neoplasms with only 55 documented cases in the English literature so far. A 19-year-old female exhibited hirsutism and was found to have a cystic mass measuring 5.8 cm × 3.9 cm × 5.8 cm in the left retroperitoneum. During subsequent workup a high pre-operative value of dehydroepiandrosterone sulfate (DHEAS) was noted. The patient was referred to surgical oncology and underwent an uneventful laparoscopic cystectomy. Pathology classified the cyst as PRMC. Post-operatively, the patient's DHEAS levels normalized, though there was...
Source: Clinical Medicine and Research - October 3, 2019 Category: General Medicine Authors: Danen C, Leschke T, Bassi D, Sharma R Tags: Clin Med Res Source Type: research

Staphylococcus aureus Resistance Patterns in Wisconsin: 2018 Surveillance of Wisconsin Organisms for Trends in Antimicrobial Resistance and Epidemiology (SWOTARE) Program Report.
CONCLUSIONS: Several antimicrobial agents continue to demonstrate in vitro efficacy against clinical isolates of S. aureus (including MRSA) throughout Wisconsin, including three agents with recently-published susceptibility testing guidelines. However, continued surveillance efforts may be necessary in the Lake Winnebago, Southeast, and Southcentral regions to further assess higher rates of resistance to a number of antimicrobial agents. PMID: 31582419 [PubMed - as supplied by publisher] (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - October 3, 2019 Category: General Medicine Authors: Schulte RH, Munson E Tags: Clin Med Res Source Type: research

A Case of Isolated Unilateral Glossopharyngeal Nerve Palsy.
This article discusses the various etiologies and mechanisms of this rare condition. It is unique because of the nerve's location and relation to other structures. PMID: 31511240 [PubMed - as supplied by publisher] (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - September 11, 2019 Category: General Medicine Authors: Savarimuthu MK, Nair AK Tags: Clin Med Res Source Type: research

Hepatitis C Virus-associated Acalculous Cholecystitis and Review of the Literature.
We report on a patient who was first diagnosed with chronic Hepatic C infection and subsequently acalculous cholecystitis. PMID: 31511241 [PubMed - as supplied by publisher] (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - September 11, 2019 Category: General Medicine Authors: Wright WF, Palisoc K, Pinto CN, Lease JA, Baghli S Tags: Clin Med Res Source Type: research

GH-IGF1 Axis in Children with Cystic Fibrosis.
In this study we compared BMI, height, weight, IGF-I, GHBP and GHR gene expression values (evaluated by Chemiluminescent Immunometric assay; ELISA and Real time PCR respectively) in CF patients diagnosed through NBS (New born screening), or by symptoms (Late Diagnosis (LD)) and in healthy controls. RESULTS: BMI increased significantly in patients between the time of diagnosis and check-ups (p
Source: Clinical Medicine and Research - August 28, 2019 Category: General Medicine Authors: Pagani S, Bozzola E, Acquafredda G, Terlizzi V, Raia V, Maio F, Villani A, Bozzola M Tags: Clin Med Res Source Type: research

Neuropsychiatric Adverse Events from Topical Ophthalmic Timolol.
Abstract Timolol is a commonly-used topical antiglaucoma medication and has proven to be highly efficacious for most recipients. Among the reported adverse events, the neuropsychiatric spectrum has been cited, albeit for a small proportion of those treated. This review summarizes the cumulative published experience of such side effects and assesses the quality of evidence. As for other beta-blockers, whether orally or topically administered, various central nervous systems dysfunctions have been detailed in either case reports or larger patient series. The adverse event commonly resolves following drug termination...
Source: Clinical Medicine and Research - August 28, 2019 Category: General Medicine Authors: Cimolai N Tags: Clin Med Res Source Type: research

Tattoo Koebnerization and Severe Pulmonary Hypertension.
PMID: 31462539 [PubMed - as supplied by publisher] (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - August 28, 2019 Category: General Medicine Authors: Patel M, Ladak K Tags: Clin Med Res Source Type: research

Effectiveness of Standardized Patient in Abdominal Physical Examination Education: A Randomized, Controlled Trial.
Abstract INTRODUCTION: Simulation and virtual technologies currently are used to enhance basic and advanced nursing skills. Information on the use of simulation methods in the Iranian nursing education system, particularly regarding standardized patients (SP), is scarce. Hence, the present study aimed to evaluate the effect of using SP on the performance of Iranian nursing students in the physical examination of the abdomen. In addition, the SP method was compared with the purely lecture-based education method. METHODS: The present study was of a pre-test/post-test design carried out at the School of Nursing ...
Source: Clinical Medicine and Research - June 1, 2019 Category: General Medicine Authors: Jaberi A, Momennasab M Tags: Clin Med Res Source Type: research

Assessing Prognosis of Acute Coronary Syndrome in Recent Clinical Trials: A Systematic Review.
Abstract There is no recent comprehensive overview of contemporary clinical trials assessing short and long-term outcomes in patients with acute coronary syndrome (ACS). This paper reviews factors from recent clinical trials that influenced prognosis in patients with ACS. Cochrane and PubMed databases were screened systematically for clinical trials published in the English literature reporting on ACS prognosis. Two authors independently screened titles, abstracts, and full text. Studies meeting inclusion criteria evaluated the impact of modern practice on prognosis. In vitro and animal models studies, conference ...
Source: Clinical Medicine and Research - June 1, 2019 Category: General Medicine Authors: Ye F, Winchester D, Jansen M, Lee A, Silverstein B, Stalvey C, Khuddus M, Mazza J, Yale S Tags: Clin Med Res Source Type: research

Recognizing Poor Sleep Quality Factors During Oral Health Evaluations.
Abstract Oral health practitioners routinely perform oral health assessments for the dental patient to determine if oral disease is present. Systemic health is often a contributor to oral health concerns. One area in particular that has a direct effect on oral structures and oral health is poor sleep quality and open mouth breathing. Sleep is a fundamental process of the human body, which regulates core biological functions. Sleep quality reflects a person's ability to fall asleep, stay asleep, and enter into the various rejuvenating sleep cycles for the full duration. A person who does not obtain quality sleep ca...
Source: Clinical Medicine and Research - June 1, 2019 Category: General Medicine Authors: Schroeder K, Gurenlian JR Tags: Clin Med Res Source Type: research

Nivolumab-Associated Acute Demyelinating Encephalitis: A Case Report and Literature Review.
We present a 59-year-old Caucasian woman with a history of treatment-resistant, progressive, laryngeal squamous cell carcinoma. She received nivolumab and presented with gradual weakness, confusion, and progressive dyspnea. Magnetic resonance imaging of the head showed multifocal cerebral demyelination, primarily involving the parietal lobe. The diagnosis of acute demyelinating encephalitis was made. She improved dramatically after stopping nivolumab and receiving treatment with high-dose intravenous steroid and immunoglobin therapy. We conclude, from this case and literature review, that immune checkpoint inhibitor treatm...
Source: Clinical Medicine and Research - June 1, 2019 Category: General Medicine Authors: Zafar Z, Vogler C, Hudali T, Bhattarai M Tags: Clin Med Res Source Type: research

Cocaine-Induced Bronchospasm Mimicking Acute Asthma Exacerbation.
Abstract Cocaine can cause a myriad of changes in the lung, which can range from bronchoconstriction to destruction of the alveolar-capillary membrane and acute lung injury. Cocaine-induced bronchospasm is a diagnosis of exclusion that should be considered when the clinical presentation of acute hypoxic and hypercapneic respiratory failure cannot be explained by chronic obstructive pulmonary disease or asthma exacerbation, anaphylaxis to food or medications, exercise, or infection. Here, we present two patients with acute hypoxic and hypercapneic respiratory failure that was ultimately attributed to cocaine use sh...
Source: Clinical Medicine and Research - June 1, 2019 Category: General Medicine Authors: Zhou CY, Ricker M, Pathak V Tags: Clin Med Res Source Type: research

Prolongation of Second Twin's Delivery Until Term: A Rare Case of Delayed-Interval Delivery.
We report a case of delayed-interval delivery wherein prolongation of the second twin's delivery until term with a subsequent favorable infantile outcome. In this case, the stillbirth of the first twin occurred at 25 weeks' gestation. Prophylactic tocolysis was performed with ritodrine and magnesium sulfate, and a McDonald cerclage was performed 2 days after delivery of the first twin. Ampicillin and gentamicin were also administered for the purpose of prevention of intrauterine infection. No clinical sign of chorioamnionitis was found thereafter, and full term uneventful delivery was achieved. With this experience, we bel...
Source: Clinical Medicine and Research - June 1, 2019 Category: General Medicine Authors: Imachi Y, Hidaka N, Kai S, Hachisuga M, Kato K Tags: Clin Med Res Source Type: research

Contagious Horror: Infectious Themes in Fiction and Film.
Abstract Infectious diseases have been a preeminent part of literature since the earliest human writings. In particular, they have contributed greatly to the genre of horror-written or visual art intended to startle or scare. Horror fiction has emphasized infectious themes from the earliest Babylonian and Hebrew texts. In medieval times, stories of vampires and werewolves often had a contagious component, and pivotal works of Victorian horror centered around fear of infection and contamination. As film became prominent in the 20th Century, a strong emphasis on themes of plague and apocalypse developed. An analysis...
Source: Clinical Medicine and Research - June 1, 2019 Category: General Medicine Authors: Sartin JS Tags: Clin Med Res Source Type: research

Abdominal Physical Signs and Medical Eponyms: Part II. Physical Examination of Palpation, 1907-1926.
CONCLUSION: We describe brief historical background information about the physician who reported the sign, original description of the sign, and its clinical application and implication into today's medical practice. PMID: 31160480 [PubMed - in process] (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - June 1, 2019 Category: General Medicine Authors: Rastogi V, Singh D, Tekiner H, Ye F, Mazza JJ, Yale SH Tags: Clin Med Res Source Type: research

Cardiac Dysfunction in Adult Patients with Traumatic Brain Injury: A Prospective Cohort Study.
CONCLUSIONS: Cardiac dysfunction occurs in patients after moderate to severe TBI, with mild to moderate reduction in left ventricular ejection fraction. Patients who developed cardiac dysfunction after TBI had a higher prevalence of diabetes mellitus and higher proportion of abnormalities in electrocardiograms. Development of cardiac dysfunction was not associated with adverse clinical outcomes. PMID: 30587559 [PubMed - in process] (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - December 1, 2018 Category: General Medicine Authors: Venkata C, Kasal J Tags: Clin Med Res Source Type: research

Metastatic Prostate Cancer in a RAD51C Mutation Carrier.
Abstract A man, aged 61 years, with a history of hypogonadism and family history of cancer experienced persistent urinary difficulties with no visible prostate abnormalities. Laboratory testing and diagnostic imaging revealed a primary lesion in the prostate with lymph node involvement and multiple bone metastases. Treatment with androgen-deprivation therapy, 17,20-lyase inhibition, and bisphosphonates for 7 months was unsuccessful in preventing disease progression, but second-line chemotherapy and continued androgen-deprivation therapy improved prostate specific antigen levels. During the patient's second treatme...
Source: Clinical Medicine and Research - December 1, 2018 Category: General Medicine Authors: Potugari BR, Engel JM, Onitilo AA Tags: Clin Med Res Source Type: research

A Multidisciplinary Approach to Management of Bouveret Syndrome.
We describe a multidisciplinary approach to management of Bouveret Syndrome that could be adopted by healthcare systems with resources commonly found in facilities with a general urologist and gastroenterologist or general surgeon. Successful application of laser lithotripsy under endoscopic guidance sufficiently fractured the stone to allow for disimpaction and relief of the gastric outlet obstruction. PMID: 30587561 [PubMed - in process] (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - December 1, 2018 Category: General Medicine Authors: Watson RS, Folkers TE, Van Every MJ Tags: Clin Med Res Source Type: research

Abdominal Physical Signs and Medical Eponyms: Movements and Compression.
CONCLUSION: These active and passive maneuvers of the abdomen, reported as medical signs, have variable performance in medical practice. The lack of diagnostic accuracy may be attributed to confounders such as the position of the organ, modification of the original technique, or lack of performance of the maneuver as originally intended. PMID: 30587562 [PubMed - in process] (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - December 1, 2018 Category: General Medicine Authors: Rastogi V, Singh D, Tekiner H, Ye F, Mazza JJ, Yale SH Tags: Clin Med Res Source Type: research

Traction Diverticulum of the Small Bowel with Enterolith as a Cause of Intestinal Obstruction.
PMID: 30587563 [PubMed - in process] (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - December 1, 2018 Category: General Medicine Authors: Gachabayov M, Orujova L, Kubachev K Tags: Clin Med Res Source Type: research

Subject Index: Volume 16, 2018.
Authors: PMID: 30587564 [PubMed - in process] (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - December 1, 2018 Category: General Medicine Tags: Clin Med Res Source Type: research

Author Index: Volume 16, 2018.
Authors: PMID: 30587565 [PubMed - in process] (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - December 1, 2018 Category: General Medicine Tags: Clin Med Res Source Type: research

Reviewers: Volume 16.
Authors: PMID: 30587566 [PubMed - in process] (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - December 1, 2018 Category: General Medicine Tags: Clin Med Res Source Type: research

Abdominal Physical Signs and Medical Eponyms: Part I. Physical Examination of Palpation, 1876-1907.
CONCLUSION: We present brief historical background information about the physician who reported the sign, original description of the sign, and its clinical application and implication in today's medical practice. PMID: 30166497 [PubMed - as supplied by publisher] (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - August 30, 2018 Category: General Medicine Authors: Rastogi V, Singh D, Tekiner H, Ye F, Kirchenko N, Mazza JJ, Yale SH Tags: Clin Med Res Source Type: research

Infectious Mononucleosis and Lyme Disease as Confounding Diagnoses: A Report of 2 Cases.
We describe the clinical presentation of two children with confirmed early Lyme disease and features suggestive of infectious mononucleosis, including one case of probable Lyme and EBV co-infection. PMID: 30166498 [PubMed - as supplied by publisher] (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - August 30, 2018 Category: General Medicine Authors: Koester TM, Meece JK, Fritsche TR, Frost HM Tags: Clin Med Res Source Type: research

Effect of Near-Infrared Light Therapy Based on Acupoints on the Severity of Restless Legs Syndrome in Patients Undergoing Hemodialysis: A Single-Blind Randomized Controlled Trial.
Abstract INTRODUCTION: Restless legs syndrome (RLS) is a common disorder in hemodialysis patients. The present study was conducted to determine the effect of near-infrared (NIR) light therapy given to acupoints on the severity of RLS in patients undergoing hemodialysis. METHODS: This single-blind randomized controlled trial was performed on 60 hemodialysis patients with RLS. Participants who met the inclusion criteria were randomly assigned to an intervention group (n = 30) or a control group (n = 30). Data were collected using the International Restless Legs Syndrome Rating Scale (IRLSRS) and demographic inf...
Source: Clinical Medicine and Research - May 18, 2018 Category: General Medicine Authors: Mohammadi MM, Raygani AAV, Ghobadi A, Samadzadeh S, Salari N Tags: Clin Med Res Source Type: research

Treatment-Refractory Mania with Psychosis in a Post-Transplant Patient on Tacrolimus: A Case Report.
We report here a case of a 66 year old Caucasian female, previously diagnosed with Bipolar disorder who developed treatment refractory mania with psychotic feature after being on Tacrolimus (an immunosuppressive agent) after kidney transplantation. PMID: 29776917 [PubMed - as supplied by publisher] (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - May 18, 2018 Category: General Medicine Authors: Ithman M, Malhotra K, Bordoloi M, Singh G Tags: Clin Med Res Source Type: research

A Descriptive Study of Chlorhexidine as a Disinfectant in Cleft Palate Surgery.
CONCLUSIONS: This study demonstrated that 61 of the total of 113 pathogens isolated (54%), survived after 2 minutes of disinfecting the surgical and surrounding area with CHG, thus intensifying the chances of post-operative infection. PMID: 29724746 [PubMed - as supplied by publisher] (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - May 3, 2018 Category: General Medicine Authors: Roode GJ, Bütow KW Tags: Clin Med Res Source Type: research

Flushing Disorders Associated with Gastrointestinal Symptoms: Part 1, Neuroendocrine Tumors, Mast Cell Disorders and Hyperbasophila.
Abstract Flushing is the subjective sensation of warmth accompanied by visible cutaneous erythema occurring throughout the body with a predilection for the face, neck, pinnae, and upper trunk where the skin is thinnest and cutaneous vessels are superficially located and in greatest numbers. Flushing can be present in either a wet or dry form depending upon whether neural-mediated mechanisms are involved. Activation of the sympathetic nervous system results in wet flushing, accompanied by diaphoresis, due to concomitant stimulation of eccrine sweat glands. Wet flushing is caused by certain medications, panic disord...
Source: Clinical Medicine and Research - April 12, 2018 Category: General Medicine Authors: Rastogi V, Singh D, Mazza JJ, Yang D, Parajuli D, Yale SH Tags: Clin Med Res Source Type: research

Flushing Disorders Associated with Gastrointestinal Symptoms: Part 2, Systemic Miscellaneous Conditions.
Abstract Flushing disorders with involvement of the gastrointestinal tract represent a heterogeneous group of conditions. In part 1 discussed were neuroendocrine tumors (NET), mast cell activation disorders (MCAD), and hyperbasophilia. In this section are covered the remaining flushing disorders which primarily or secondarily involves the gastrointestinal tract. This includes dumping syndrome, mesenteric traction syndrome, rosacea, hyperthyroidism and thyroid storm, anaphylaxis, panic disorders, paroxysmal extreme pain disorder, and food, alcohol and medications. With the exception of paroxysmal pain disorders, pa...
Source: Clinical Medicine and Research - April 12, 2018 Category: General Medicine Authors: Rastogi V, Singh D, Mazza JJ, Yang D, Parajuli D, Yale SH Tags: Clin Med Res Source Type: research

Beh çet's Disease: Pulmonary Aneurysm Resolution with Oral Therapy and HLA B72 Allele Association.
We report the case of a female patient who was diagnosed with a pulmonary artery aneurysm that was caused by Behçet's disease. The patient was initially diagnosed with community-acquired pneumonia and then pulmonary thromboembolism and aneurysm of the right pulmonary artery segmental branch was confirmed. The initial treatment consisted of anticoagulant drugs. After analysis of the family history and a positive pathergy test, the patient was diagnosed with Behçet's disease. Oral pharmacological treatment began with corticosteroids, cyclophosphamide, and anticoagulant suspension. The HLA B72 allele was identif...
Source: Clinical Medicine and Research - April 2, 2018 Category: General Medicine Authors: de Albuquerque Botura C, Bersani-Amado LE, Zacarias-Júnior AR, Boreli SD, Stecca NGG, da Rocha BA, Cuman RKN, Bersani-Amado CA Tags: Clin Med Res Source Type: research

Biologic Agent-Associated Cutaneous Adverse Events: A Single Center Experience.
Abstract Biologic agents are regarded as an effective treatment for a variety of autoimmune diseases. These drugs have an acceptable safety and tolerability profile, although an increasing number of autoimmune conditions have been reported with their use. Additionally, a variety of cutaneous diseases have been associated with their use. Here we report our experience of adverse cutaneous events with the use of biologic agents. An alternative explanation for patients presenting with adverse cutaneous events including drug interactions must be carefully investigated. PMID: 29610119 [PubMed - as supplied by publi...
Source: Clinical Medicine and Research - April 2, 2018 Category: General Medicine Authors: Sehgal R, Stratman EJ, Cutlan JE Tags: Clin Med Res Source Type: research

The Role of Moisturizers in Addressing Various Kinds of Dermatitis: A Review.
Abstract Moisturizer is a major component of basic daily skin care, particularly in presence of epidermal barrier alteration and reduced epidermal water content. It is an important part of a dermatologist's strategy to maintain skin health as well as treating various dermatoses which co-exist with skin dryness, linked to impaired skin barrier function such as in atopic disorder as well as other types of dermatitis. Mastering the knowledge regarding action mechanism, application, dosage, adverse effects as well as specific clinical usage of moisturizers is must for a dermatologist, in order to support the capabilit...
Source: Clinical Medicine and Research - December 11, 2017 Category: General Medicine Authors: Purnamawati S, Satria B, Indrastuti N, Danarti R, Saefudin T Tags: Clin Med Res Source Type: research

Update on Electronic Dental Record and Clinical Computing Adoption Among Dental Practices in the United States.
Abstract The study sought to re-characterize trends and factors affecting electronic dental record (EDR) and technologies adoption by dental practices and the impact of the Health Information Technology for Economic and Clinical Health (HITECH) act on adoption rates through 2012. A 39-question survey was disseminated nationally over 3 months using a novel, statistically-modeled approach informed by early response rates to achieve a predetermined sample. EDR adoption rate for clinical support was 52%. Adoption rates were higher among: 1) younger dentists; 2) dentists ≤ 15 years in practice; 3) females; and 4) gr...
Source: Clinical Medicine and Research - December 11, 2017 Category: General Medicine Authors: Acharya A, Schroeder D, Schwei K, Chyou PH Tags: Clin Med Res Source Type: research

Recurrent Hemobilia Due to Right Hepatic Artery Pseudoaneurysm.
Abstract Hemobilia is a potentially life-threatening clinical issue in the etiology of which iatrogenesis is playing increasingly more immense role. Nowadays the most frequent etiology of hemobilia has shifted toward iatrogenesis owing to increasingly more frequent performance of liver procedures, either open or minimally invasive. Here we report a rare case of recurrent hemobilia after transarterial embolization. A 57-year-old male patient after cholecystectomy presented with Quincke's triad. CT revealed a pseudoaneurysm of the right hepatic artery. Transarterial embolization failed, hemobilia recurred. The patie...
Source: Clinical Medicine and Research - December 1, 2017 Category: General Medicine Authors: Gachabayov M, Kubachev K, Mityushin S, Zarkua N Tags: Clin Med Res Source Type: research

Fibrillary Glomerulonephritis in Primary Sjogren's Syndrome: A Rare Cause of Renal Failure.
We describe the diagnostic work-up, clinical course, treatment utilized, and 1-year follow-up. There is one other case in the literature of FGN in a patient with pSS. The rarity of this association and distinction of FGN from other forms of renal involvement in pSS is important as it impacts therapy and prognosis. The case highlights electron microscopy findings in FGN and poor prognosis. PMID: 29196420 [PubMed - as supplied by publisher] (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - December 1, 2017 Category: General Medicine Authors: Sehgal R, Sajjad SM, Thapa JK Tags: Clin Med Res Source Type: research

Anisocoria Secondary to Anticholinergic Mydriasis from Homeopathic Similasan Pink-Eye-Relief Drops.
Abstract A 70-year-old-woman developed anisocoria after applying homeopathic eye drops (Similasan Pink Eye Relief) to her left eye. Her pupil was dilated for two weeks and did not respond to light or near stimuli for one week. Both 0.1 % and 1% pilocarpine failed to constrict her left pupil, and magnetic resonance imaging of her brain did not reveal any abnormality. The eye drops she had used contain belladonna extracts, which have a natural atropine component. This case demonstrates the importance, when evaluating a patient presenting with anisocoria, of knowing the chemical ingredients of the homeopathic eye dro...
Source: Clinical Medicine and Research - October 17, 2017 Category: General Medicine Authors: Chen L, Yeung JC, Anderson DR Tags: Clin Med Res Source Type: research

Mid-Upper-Arm Circumference and Arm-to-Height Ratio to Identify Obesity in School-Age Children.
Abstract BACKGROUND: In resource-poor settings, anthropometric parameters are evaluated as potential alternatives to the body mass index (BMI) for detecting overweight and obesity in children. To this end, the mid-upper arm circumference (MUAC) and the mid-upper arm circumference to height ratio (AHtR) were evaluated as proxies to BMI in Thai school-age children. STUDY DESIGN: An observational, cross-sectional study was performed on school-aged children. PARTICIPANTS: Children in grades 1 through 6 at all public elementary schools in the Ongkharak district, Nakhon Nayok, Thailand during May and June 2013...
Source: Clinical Medicine and Research - October 10, 2017 Category: General Medicine Authors: Rerksuppaphol S, Rerksuppaphol L Tags: Clin Med Res Source Type: research

The Clinical Presentation of Subcutaneous Phaeohyphomycosis: A Case Series from Yetebon, Ethiopia.
We describe the cases of 3 men from Ethiopia who were seen and are being treated by American doctors who traveled there on a medical mission. PMID: 29018005 [PubMed - as supplied by publisher] (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - October 10, 2017 Category: General Medicine Authors: Kang RB, Simonson DC, Stoner SE, Agger WA Tags: Clin Med Res Source Type: research

Treatment-Refractory Sternocostoclavicular Hyperostosis.
We report a patient with a long history of SCCH in whom pamidronate 60 mg intravenously every 3 months for 3 years failed to reduce symptom severity and improve radiologic findings. PMID: 28751466 [PubMed - in process] (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - June 1, 2017 Category: General Medicine Authors: Yachoui R, Kreidy M, Parker BJ Tags: Clin Med Res Source Type: research

Recurrent Thrombosis in Patients with Antiphospholipid Syndrome Receiving Newer Oral Anticoagulants: A Case Report and Review of Literature.
We present the case of a patient with primary APS who had a recurrence of thrombotic event while on treatment with rivaroxaban and had to be restarted on warfarin. The current literature on recurrence of thrombotic events in patients with antiphospholipid syndrome (APS) treated with newer oral anticoagulants (NOAC) is also reviewed. Relevant case reports and case series were identified by searching the Medline database using the key words antiphospholipid syndrome, anticoagulants and names of the NOACs, and data on individual patients was abstracted. We identified several reports on the failure of newer anticoagulants in A...
Source: Clinical Medicine and Research - June 1, 2017 Category: General Medicine Authors: Joshi A, Hong J, Siva C Tags: Clin Med Res Source Type: research

Incidence of Primary Biliary Cholangitis in a Rural Midwestern Population.
CONCLUSIONS: The overall incidence of PBC in a Midwestern population of the United States has remained relatively stable over the last two decades. Patients have better prognosis, and the survival of PBC cases has improved. PMID: 28487448 [PubMed - as supplied by publisher] (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - May 9, 2017 Category: General Medicine Authors: Kanth R, Shrestha RB, Rai I, VanWormer JJ, Roy PK Tags: Clin Med Res Source Type: research

Voriconazole-induced Periostitis Deformans: A Mimicker of HPOA.
PMID: 28487449 [PubMed - as supplied by publisher] (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - May 9, 2017 Category: General Medicine Authors: Ladak K, Rubin L Tags: Clin Med Res Source Type: research

Pulmonary MALT Lymphoma in Patients with Sjogren's Syndrome.
Abstract To describe clinical features and outcomes of seven patients with pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma in the setting of underlying primary Sjogren's syndrome from a single center, we reviewed medical records of consecutive patients with pulmonary MALT lymphoma evaluated at our facility from January 1, 1999 to December 31, 2015 for clinical features, laboratory, pathologic and radiographic findings, management, and outcomes. Out of 13 patients with pulmonary MALT lymphoma, 7 (54 %) met the criteria for Sjogren's syndrome. The mean age at lymphoma diagnosis was 66 years; male-female ...
Source: Clinical Medicine and Research - May 9, 2017 Category: General Medicine Authors: Yachoui R, Leon C, Sitwala K, Kreidy M Tags: Clin Med Res Source Type: research

Exploring Gender Difference in Sleep Quality of Young Adults: Findings from a Large Population Study.
CONCLUSION: Our findings indicate that female vulnerability to poor sleep quality should be explored beyond psycho-social disparities. Perhaps, exploring if the female predisposition to poor sleep quality originates at the biological level could lead to the answer. PMID: 28188139 [PubMed - in process] (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - December 1, 2016 Category: Journals (General) Authors: Fatima Y, Doi SA, Najman JM, Mamun AA Tags: Clin Med Res Source Type: research

Angioimmunoblastic T-Cell Lymphoma with Polyarthritis Resembling Rheumatoid Arthritis.
We report the case of a 50-year-old female who presented with lymphadenopathy, rash, and symmetric polyarthritis. She was later diagnosed with AITL and was treated with chemotherapy with resolution of arthritis. AITL should be suspected in paitents presenting with rheumatoid-like arthritis and diffuse lymphadenopathy. PMID: 28188140 [PubMed - in process] (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - December 1, 2016 Category: Journals (General) Authors: Yachoui R, Farooq N, Amos JV, Shaw GR Tags: Clin Med Res Source Type: research

Subacute Sclerosing Panencephalitis in a Child with HIV Co-Infection.
We report a child who developed subacute sclerosing panencephalitis following a short latency period and a rapidly progressive course with HIV co-infection. PMID: 27777245 [PubMed - as supplied by publisher] (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - October 24, 2016 Category: Journals (General) Authors: Maurya PK, Thakkar MD, Kulshreshtha D, Singh AK, Thacker AK Tags: Clin Med Res Source Type: research

Dietary Nitrate Acutely and Markedly Increased Exhaled Nitric Oxide in a Cystic Fibrosis Case.
We present the case of a 12 year-old, athletic male with CF who demonstrated acute but marked increases in exhaled NO following dietary nitrate consumption compared to placebo. PMID: 27630187 [PubMed - as supplied by publisher] (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - September 14, 2016 Category: Journals (General) Authors: Kerley CP, Kilbride E, Greally P, Elnazir B Tags: Clin Med Res Source Type: research