Perinatal Prognosis of Pregnancies with Single Umbilical Artery in a Romanian Third-Level Unit
Conclusions: Perinatal prognosis regarding SUA is significantly poorer than in cases without this pathology. One-third of fetuses with SUA were associated with fetal anomalies. The most common pathologies associated with SUA were cardiovascular, limb, urogenital, and digestive system malformations. Our data are similar to those described in other studies; therefore, we conclude, we can implement the general recommendations in our region regarding counselling patients.PMID:38296637 | DOI:10.3121/cmr.2023.1775 (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - January 31, 2024 Category: General Medicine Authors: J ános Levente Turos Emmanuel Ladanyi Tam ás Szabó B éla Szabó Source Type: research

"Dialogue Between Franklin and the Gout" Reexamined
Clin Med Res. 2023 Dec;21(4):196-200. doi: 10.3121/cmr.2023.1833.ABSTRACTBenjamin Franklin, one of the founding fathers of the United States, was not just a politician and a political philosopher but an inventor with a scientific temperament. He was overweight and likely suffered from the consequences of metabolic syndrome including gout. He woke up with a gout attack on October 22, 1780 and wrote the "Dialogue Between Franklin and the Gout." His observations on the risk factors for gout are re-examined in the modern context 243 years later.PMID:38296638 | DOI:10.3121/cmr.2023.1833 (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - January 31, 2024 Category: General Medicine Authors: Mary Mikhael Chokkalingam Siva Source Type: research

Meningitis in the Guise of Dementia: Lyme-Induced Normal Pressure Hydrocephalus
Clin Med Res. 2023 Dec;21(4):226-229. doi: 10.3121/cmr.2023.1829.ABSTRACTWhile the cause of altered mentation in the elderly may be multifactorial, infectious etiologies may be missed. This case report aims to detail an account of a patient with dementia, found to have Lyme meningitis in the setting of a normal pressure hydrocephalus (NPH). The patient smelled of urine and presented with ambulatory dysfunction, fitting the "wet, wacky, and wobbly" triad of NPH while also having subjective chills and leukocytosis. Non-contrast brain CT scan showed dilated ventricles. Cerebrospinal fluid (CSF) studies suggested aseptic menin...
Source: Clinical Medicine and Research - January 31, 2024 Category: General Medicine Authors: Ryan Liu Matheus Polly Robert P Lennon Alexis Reedy-Cooper Source Type: research

A Systematic Review of Interleukin-17 in Oral Lichen Planus: From Etiopathogenesis to Treatment
Clin Med Res. 2023 Dec;21(4):201-215. doi: 10.3121/cmr.2023.1822.ABSTRACTLichen planus (LP) is a chronic autoimmune disease of skin and mucous membranes. World Health Organization has announced oral lichen planus (OLP) as a premalignant lesion. The exact etiology of OLP remains unknown; however, different mechanisms may be involved in its immunopathogenesis. The upregulation of cytokines, chemokines, and adhesion molecules is consistent with a persistent and erratic immunological response to OLP-mediated antigens generated by oral keratinocytes and innate immune cells. These molecules attract T cells, and mast cells to the...
Source: Clinical Medicine and Research - January 31, 2024 Category: General Medicine Authors: Farzaneh Agha-Hosseini Mahdieh-Sadat Moosavi Hosna Bahrami Source Type: research

Compliance of Prone Positioning in Non-Intubated COVID-19 Patients
Clin Med Res. 2023 Dec;21(4):171-176. doi: 10.3121/cmr.2023.1830.NO ABSTRACTPMID:38296641 | DOI:10.3121/cmr.2023.1830 (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - January 31, 2024 Category: General Medicine Authors: Christopher G Bargoud Tingyu Jih Danika Baskar Lindsay Volk Sheraz Siddiqui Mafudia Suaray Rory Ulloque Sara Khalil Rachel L Choron Source Type: research

Investigating the Effect of Temperature Therapy on the Severity of Restless Legs Syndrome: Systematic Review and Meta-Analysis
Conclusion: The present study findings suggested temperature therapy could mildly reduce the severity of RLS symptoms. It was also found that the highest efficacy of this intervention could be achieved when the higher temperature was used in fewer treatment sessions in hemodialysis patients. Based on our findings, this intervention can be included in the care plan of patients with RLS considering the settings described to achieve the highest efficacy.PMID:38296642 | DOI:10.3121/cmr.2023.1824 (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - January 31, 2024 Category: General Medicine Authors: Mohammad Mehdi Mohammadi Ali Akbar Vaisi Raygani Source Type: research

Distance Matters: Investigating No-Shows in a Large Rural Provider Network
Conclusion: Our analysis showed patients who lived <5 miles and >20 miles from the clinic had higher no-show rates. The odds of a no-show were comparable between patients who showed up and those who did not. Male patients, Spanish-speaking patients, patients with a history of no-shows, and Medicaid beneficiaries were more likely to miss their appointments. Understanding the impact of these variables on no-show rates can assist healthcare providers in developing strategies to improve patient access and reduce no-show rates. These findings imply that rural patients may face a variety of barriers when seeking healthcare...
Source: Clinical Medicine and Research - January 31, 2024 Category: General Medicine Authors: Abdul Shour Adedayo A Onitilo Source Type: research

Perinatal Prognosis of Pregnancies with Single Umbilical Artery in a Romanian Third-Level Unit
Conclusions: Perinatal prognosis regarding SUA is significantly poorer than in cases without this pathology. One-third of fetuses with SUA were associated with fetal anomalies. The most common pathologies associated with SUA were cardiovascular, limb, urogenital, and digestive system malformations. Our data are similar to those described in other studies; therefore, we conclude, we can implement the general recommendations in our region regarding counselling patients.PMID:38296637 | DOI:10.3121/cmr.2023.1775 (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - January 31, 2024 Category: General Medicine Authors: J ános Levente Turos Emmanuel Ladanyi Tam ás Szabó B éla Szabó Source Type: research

"Dialogue Between Franklin and the Gout" Reexamined
Clin Med Res. 2023 Dec;21(4):196-200. doi: 10.3121/cmr.2023.1833.ABSTRACTBenjamin Franklin, one of the founding fathers of the United States, was not just a politician and a political philosopher but an inventor with a scientific temperament. He was overweight and likely suffered from the consequences of metabolic syndrome including gout. He woke up with a gout attack on October 22, 1780 and wrote the "Dialogue Between Franklin and the Gout." His observations on the risk factors for gout are re-examined in the modern context 243 years later.PMID:38296638 | DOI:10.3121/cmr.2023.1833 (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - January 31, 2024 Category: General Medicine Authors: Mary Mikhael Chokkalingam Siva Source Type: research

Meningitis in the Guise of Dementia: Lyme-Induced Normal Pressure Hydrocephalus
Clin Med Res. 2023 Dec;21(4):226-229. doi: 10.3121/cmr.2023.1829.ABSTRACTWhile the cause of altered mentation in the elderly may be multifactorial, infectious etiologies may be missed. This case report aims to detail an account of a patient with dementia, found to have Lyme meningitis in the setting of a normal pressure hydrocephalus (NPH). The patient smelled of urine and presented with ambulatory dysfunction, fitting the "wet, wacky, and wobbly" triad of NPH while also having subjective chills and leukocytosis. Non-contrast brain CT scan showed dilated ventricles. Cerebrospinal fluid (CSF) studies suggested aseptic menin...
Source: Clinical Medicine and Research - January 31, 2024 Category: General Medicine Authors: Ryan Liu Matheus Polly Robert P Lennon Alexis Reedy-Cooper Source Type: research

A Systematic Review of Interleukin-17 in Oral Lichen Planus: From Etiopathogenesis to Treatment
Clin Med Res. 2023 Dec;21(4):201-215. doi: 10.3121/cmr.2023.1822.ABSTRACTLichen planus (LP) is a chronic autoimmune disease of skin and mucous membranes. World Health Organization has announced oral lichen planus (OLP) as a premalignant lesion. The exact etiology of OLP remains unknown; however, different mechanisms may be involved in its immunopathogenesis. The upregulation of cytokines, chemokines, and adhesion molecules is consistent with a persistent and erratic immunological response to OLP-mediated antigens generated by oral keratinocytes and innate immune cells. These molecules attract T cells, and mast cells to the...
Source: Clinical Medicine and Research - January 31, 2024 Category: General Medicine Authors: Farzaneh Agha-Hosseini Mahdieh-Sadat Moosavi Hosna Bahrami Source Type: research

Compliance of Prone Positioning in Non-Intubated COVID-19 Patients
Clin Med Res. 2023 Dec;21(4):171-176. doi: 10.3121/cmr.2023.1830.NO ABSTRACTPMID:38296641 | DOI:10.3121/cmr.2023.1830 (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - January 31, 2024 Category: General Medicine Authors: Christopher G Bargoud Tingyu Jih Danika Baskar Lindsay Volk Sheraz Siddiqui Mafudia Suaray Rory Ulloque Sara Khalil Rachel L Choron Source Type: research

Investigating the Effect of Temperature Therapy on the Severity of Restless Legs Syndrome: Systematic Review and Meta-Analysis
Conclusion: The present study findings suggested temperature therapy could mildly reduce the severity of RLS symptoms. It was also found that the highest efficacy of this intervention could be achieved when the higher temperature was used in fewer treatment sessions in hemodialysis patients. Based on our findings, this intervention can be included in the care plan of patients with RLS considering the settings described to achieve the highest efficacy.PMID:38296642 | DOI:10.3121/cmr.2023.1824 (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - January 31, 2024 Category: General Medicine Authors: Mohammad Mehdi Mohammadi Ali Akbar Vaisi Raygani Source Type: research

Distance Matters: Investigating No-Shows in a Large Rural Provider Network
Conclusion: Our analysis showed patients who lived <5 miles and >20 miles from the clinic had higher no-show rates. The odds of a no-show were comparable between patients who showed up and those who did not. Male patients, Spanish-speaking patients, patients with a history of no-shows, and Medicaid beneficiaries were more likely to miss their appointments. Understanding the impact of these variables on no-show rates can assist healthcare providers in developing strategies to improve patient access and reduce no-show rates. These findings imply that rural patients may face a variety of barriers when seeking healthcare...
Source: Clinical Medicine and Research - January 31, 2024 Category: General Medicine Authors: Abdul Shour Adedayo A Onitilo Source Type: research

Perinatal Prognosis of Pregnancies with Single Umbilical Artery in a Romanian Third-Level Unit
Conclusions: Perinatal prognosis regarding SUA is significantly poorer than in cases without this pathology. One-third of fetuses with SUA were associated with fetal anomalies. The most common pathologies associated with SUA were cardiovascular, limb, urogenital, and digestive system malformations. Our data are similar to those described in other studies; therefore, we conclude, we can implement the general recommendations in our region regarding counselling patients.PMID:38296637 | DOI:10.3121/cmr.2023.1775 (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - January 31, 2024 Category: General Medicine Authors: J ános Levente Turos Emmanuel Ladanyi Tam ás Szabó B éla Szabó Source Type: research