In vitro Susceptibilities of Methicillin-Susceptible and Resistant Staphylococci to Traditional Antibiotics Compared to a Novel Fluoroquinolone
AbstractBackgroundTo assess the in-vitro efficacy of delafloxacin, a new fourth generation fluoroquinolone, againstStaphylococcus vitreous isolates from patients with clinically diagnosed endophthalmitis. This is the first investigation of delafloxacin in ocular tissues.MethodsIntravitreal isolates of culture-provenS. aureus andS. epidermidis were identified between 2014 and 2018. Minimum inhibitor concentrations (MIC) were determined using ETEST strips. The antibiotic susceptibilities were tested against a panel of drugs including glycopeptides such as vancomycin, as well as traditional and newer fluoroquinolones (levoflo...
Source: Journal of Ophthalmic Inflammation and Infection - February 27, 2020 Category: Opthalmology Source Type: research

Acute macular neuroretinopathy with coexistent central retinal vein occlusion as the presenting feature in intraocular tuberculosis
ConclusionAcute macular neuroretinopathy can complicate intraocular TB. Tuberculosis should be kept as one of the differential diagnosis in patients with AMN. Prognosis is generally good in patients of ocular TB presenting with retinal vascular occlusions. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - February 27, 2020 Category: Opthalmology Source Type: research

Branch Retinal Artery Occlusion as a presenting sign of Acute Retinal Necrosis: a rare association
ConclusionWe report this case to highlight that occlusive vasculopathy can be a presenting sign of an underlying infectious etiology in any age group. BRAO was a rare presenting sign of ARN in our patient. A thorough peripheral examination is recommended in order to avoid missing infectious pathologies such as ARN which starts from the retinal periphery, progresses fast, and if not managed on time may lead to permanent loss of vision. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - February 12, 2020 Category: Opthalmology Source Type: research

Utility of wound cultures in the management of open globe injuries: a 5-year retrospective review
ConclusionsDespite a high rate of wound contamination, few cases of endophthalmitis (1.2%) were seen in this series. In no case did the results of wound culture impact choice of antibiotic prophylaxis or treatment. Cultures obtained at the time of open globe repair were not cost effective in the subsequent management of the injury. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - February 3, 2020 Category: Opthalmology Source Type: research

Automated measurement of leakage on wide-field angiography in the assessment of retinal vasculitis
AbstractAutomated analysis of leakage on fluorescein angiography is a measurable and clinically applicable endpoint that can be used to follow patients with posterior uveitis. A number of studies have analyzed the use of automated analysis of leakage on fluorescein angiography and are reviewed in this article. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - February 3, 2020 Category: Opthalmology Source Type: research

Severe visual impairment due to an optic neuropathy and central retinal vein occlusion in a sarcoidosis patient
ConclusionsOur findings suggest neurosarcoidosis of the unilateral retrobulbar optic nerve can cause compressive optic disc edema and resembles the central retinal vein occlusion (CRVO) phenotype. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - January 31, 2020 Category: Opthalmology Source Type: research

Characterization of cyclitic membranes by ultrabiomicroscopy in patients with pars planitis
ConclusionsUBM is a valuable tool for the diagnosis of cyclitic membranes at admittance and during follow-up of patients with pars planitis; it helps the clinician to detect this complication early. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - January 27, 2020 Category: Opthalmology Source Type: research

Necrotic scleral melt and fungal keratitis —a complication of subtenon triamcinolone acetonide injection
ConclusionScleral melt is a rare complication of STAI; however, an early diagnosis and management of any predisposing factor along with surgical debridement should be considered as a potential critical treatment option to salvage the eye. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - January 27, 2020 Category: Opthalmology Source Type: research

Ozurdex (dexamethasone intravitreal implant) for the treatment of intermediate, posterior, and panuveitis: a systematic review of the current evidence
ConclusionsThe DEX implant is an effective medication for the treatment of posterior segment uveitis, uveitic macular edema, and results in improved visual acuity. Development of elevated IOP and cataract should be closely monitored as they are tangible risks associated with the DEX implant. This study was not able to determine whether the DEX implant was more effective as a monotherapy or as an adjunctive therapy to systemic immunomodulatory treatment. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - January 10, 2020 Category: Opthalmology Source Type: research

Bilateral corneal perforation and iris prolapse as a complication non-peripheral ulcerative keratitis in a patient with fulminant granulomatosis with polyangiitis: a case report
(Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - January 10, 2020 Category: Opthalmology Source Type: research

Topographic correlation between multifocal electroretinography, microperimetry, and spectral-domain optical coherence tomography of the macula in patients with birdshot chorioretinopathy
ConclusionsThe structural and functional assessments in retinae of eyes with BSCR suggest that each imaging tool may be capturing unique aspects of retinal dysfunction. Multimodal imaging may allow detailed analyses of retinal damage at various corresponding loci. These findings are important when considering the use of these techniques in BSCR. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - December 28, 2019 Category: Opthalmology Source Type: research

Diffuse unilateral subacute neuroretinitis: review article
AbstractDiffuse unilateral subacute neuroretinitis (DUSN) is an ocular infectious disease that can lead to severe visual impairment and blindness. It usually occurs in healthy young individuals and depending on the stage of the disease, it may present as vitritis, multifocal gray-white lesions in the outer retina, and derangement of the retinal pigment epithelium, narrowing of the retinal vessels and optic atrophy. Parasites of different sizes and species have been proposed as the etiologic agent of DUSN, includingAncylostoma caninum,Toxocara canis, and others. Thus, it is hypothesized that different infectious worms may b...
Source: Journal of Ophthalmic Inflammation and Infection - December 27, 2019 Category: Opthalmology Source Type: research

Optical coherence tomography angiography in uveitis
AbstractBefore the introduction of optical coherence tomography angiography (OCTA) in the early 2000s, dye-based angiography was considered the “gold standard” for the diagnosis and monitoring of ocular inflammation. OCTA is a novel technique, which demonstrates capillary networks based on the amount of light returned from moving blood cells, providing further information on pathophysiological changes in uveitis.The aim of this review is to describe the basic principles of OCTA and its application to ocular inflammatory disorders. It particularly emphasizes on its contribution not only in the diagnosis and mana...
Source: Journal of Ophthalmic Inflammation and Infection - December 23, 2019 Category: Opthalmology Source Type: research

Tuberculous scleritis in a young Asian Indian girl —a case presentation and literature review
We report a case of a 9-year-old female child who presented with bilateral non-necrotizing anterior scleritis with unilateral posterior scleritis secondary to TB. To our knowledge, this is a rare presentation in pediatric age group, and she is the youngest of few cases of tuberculous posterior scleritis reported in literature. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - December 23, 2019 Category: Opthalmology Source Type: research

Does ophthalmic-grade silicone oil possess antimicrobial properties?
ConclusionMedical-grade silicone oil used in ophthalmology exhibited in vitro bactericidal and fungistatic activity over 30  days. Insertion of silicone oil in vitrectomy for endophthalmitis, when required, could supplement the antimicrobial activities of intravitreal antibiotics in management of endophthalmitis. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - November 1, 2019 Category: Opthalmology Source Type: research

Interleukin-6 inhibition in the management of non-infectious uveitis and beyond
ConclusionStudies have shown that IL-6 inhibitors can be effective in the management of NIU. In addition, the levels of IL-6 are elevated in other ocular vascular diseases such as retinal vein occlusion and diabetic macular edema. The roles of IL-6 inhibition may be broadened in the future to include the management of retinal vascular diseases and non-uveitic macular edema. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - September 16, 2019 Category: Opthalmology Source Type: research

Paradoxical reactions in ocular tuberculosis
AbstractParadoxical reactions following initiation of anti-tubercular therapy have been documented most often in extrapulmonary tuberculosis. A combination of factors such as delayed hypersensitivity, decreased suppressor mechanisms, and an increased response to mycobacterial antigens mediated by the host ’s immune system have been implicated in the development of these reactions. Similar worsening in patients with ocular tuberculosis while on treatment has been described. It is therefore important for the clinician to be aware of this occurrence, as prompt recognition and timely institution of cor ticosteroids and i...
Source: Journal of Ophthalmic Inflammation and Infection - September 6, 2019 Category: Opthalmology Source Type: research

The broad spectrum of application of optical coherence tomography angiography to the anterior segment of the eye in inflammatory conditions: a review of the literature
ConclusionsThis review aims to establish the current application of OCTA to anterior segment disorders of the eye, with an emphasis on exploring its use in iris vessel dilation seen in various forms of iritis, as a predictive factor for further episodes of inflammation. In addition, OCTA can depict neovascularization of the iris secondary to proliferative diabetic retinopathy. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - September 4, 2019 Category: Opthalmology Source Type: research

Bilateral viral keratitis following corneal collagen crosslinking for progressive keratoconus
We describe a case that developed bilateral viral keratitis after corneal collagen crosslinking with riboflavin and ultraviolet A for progressive keratoconus.Case reportAn 18-year-old boy underwent corneal collagen crosslinking in both the eyes at the same setting for bilateral progressive keratoconus. He was discharged with a soft bandage contact lens and asked to follow up in 5  days. Seven days later, the patient returned with severe pain, redness, and photophobia for the last 2 days. The bandage contact lens was removed. There was a central corneal lesion in a branching dendritic pattern in both the eyes ...
Source: Journal of Ophthalmic Inflammation and Infection - August 28, 2019 Category: Opthalmology Source Type: research

Optimising graft survival in endothelial keratoplasty for endothelial failure secondary to cytomegalovirus endotheliitis
ConclusionTargeted aqueous sampling for CMV-DNA perioperatively guides antiviral therapy and ensures adequacy of treatment, minimising the duration of systemic valganciclovir therapy to reduce adverse effects of long-term treatment. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - August 2, 2019 Category: Opthalmology Source Type: research

Experience of using adalimumab in treating sight-threatening paediatric or adolescent Behcet ’s disease-related uveitis
AbstractPurposeTo report the clinical outcomes of adalimumab in treating refractory Behcet ’s disease (BD)-related uveitis in paediatric or adolescent patients.MethodsRetrospective review of five paediatric or adolescent patients with BD-related uveitis with a minimum follow-up of 24  months.ResultsDisease quiescence was observed in 9 (90%) of 10 eyes at 12  months. The mean number of relapses per year per patient was 5 (range, 3–7) before initiation of adalimumab treatment. This was reduced to 0.2 relapse per patient per year among the five patients during the first 24 months after startin...
Source: Journal of Ophthalmic Inflammation and Infection - July 31, 2019 Category: Opthalmology Source Type: research

Therapy-resistant dry itchy eyes
AbstractAn 8 years old male presented to our clinic with dry eye symptomes. Different therapiy attemps were made in the last few months and did not lead to any improvement. Examining this patient revealed multiple signs of vitamin A deficiency, which could confirmed by laboratory examination. The initial substitution of vitamin A led to a fast rehabilitation and a following nutrition consulting kept the patient symptom-free over 6 month follow up. Vitamin A deficiency -although rare in the developed countries- is an importent differential diagnosis of the dry eye especially in children. Vitamin A deficiency not only causes...
Source: Journal of Ophthalmic Inflammation and Infection - July 23, 2019 Category: Opthalmology Source Type: research

Effect of vitreomacular adhesion on the treatment outcomes in the STOP-Uveitis clinical trial for non-infectious uveitis
ConclusionsThe absence of VMA or development of PVD in eyes with VMA seems to have a beneficial effect on the vision of subjects receiving treatment for uveitis. Therefore, patients with uveitis should be assessed using SD-OCT for the presence of vitreomacular interface abnormalities. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - July 19, 2019 Category: Opthalmology Source Type: research

Vitreoretinal lymphoma followed by systemic diffuse large B cell lymphoma
AbstractVitreoretinal lymphoma as the presenting diagnosis in association with a systemic lymphoma without central nervous system involvement is exceedingly rare, and the classification of this condition is not well-established. Here, we describe a patient with intermittent blurry vision in the left eye for 2  years in the setting of a recent incidental diagnosis of diffuse large B cell lymphoma from an axillary lymph node biopsy. The diagnosis of panuveitis with an extensive exudative retinal detachment was made. The patient was treated with pars plana vitrectomy as well as systemic chemotherapy, intr athecal metho...
Source: Journal of Ophthalmic Inflammation and Infection - June 10, 2019 Category: Opthalmology Source Type: research

Optical coherence tomography angiography (OCTA) as a new diagnostic tool in uveitis
ConclusionOCTA as a non-invasive, depth-resolution imaging tool can give qualitative and quantitative information about the status of retinal and choroidal vessels, but also has certain limitations. Employing OCTA as a complementary rather than exclusive tool, it can give important additional information about the macro- and microvasculature under inflammatory circumstances. Thereby, it also contributes to the understanding of the pathophysiology of various uveitis entities. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - May 28, 2019 Category: Opthalmology Source Type: research

Tinea corporis infection manifestating as retinochoroiditis —an unusual presentation
ConclusionWe report this case to highlight that one must rule out an infective etiology of retinochoroiditis before starting oral corticosteroids as it may worsen the infection especially fungal as in our patient. A detailed medical history and thorough examination helped us in diagnosing a systemic infective pathology and the possible cause of retinochoroiditis. To the best of our knowledge, this is the first case of infective retinochoroiditis secondary toT. corporis to be reported. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - May 27, 2019 Category: Opthalmology Source Type: research

Infectious endophthalmitis leading to evisceration: spectrum of bacterial and fungal pathogens and antibacterial susceptibility profile
ConclusionEndophthalmitis due toPneumococci, Aspergillus, andPseudomonas can be very fulminant and progress to require evisceration in spite of prompt and appropriate treatment. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - May 16, 2019 Category: Opthalmology Source Type: research

Secondary dengue retinitis with associated occlusive retinal vasculitis
ConclusionSecondary dengue infection may manifest as retinitis with signs of microvascular occlusions in the retina. A high level of suspicion and IgG/IgM ratio may help in confirming the diagnosis. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - May 16, 2019 Category: Opthalmology Source Type: research

Non-paraneoplastic autoimmune retinopathy: multimodal testing characteristics of 13 cases
ConclusionNon-paraneoplastic autoimmune retinopathy has a wide and often challenging to diagnose spectrum of clinical symptoms and imaging findings. Immunosuppressive therapy can be considered empiric in the face of a suggestive presentation and can be initiated after an evaluation of clinical findings and multimodal testing, though treatment does not appear to affect regeneration of the ellipsoid zone on OCT or impact visual acuity. Treatment should be primarily used to prevent disease progression and contralateral eye involvement.Trial registrationN/A (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - February 26, 2019 Category: Opthalmology Source Type: research

Unilateral endogenous Candida endophthalmitis after extracorporeal shock wave lithotripsy for a renal stone in an immunocompetent woman: a case report
ConclusionEndogenous Candida endophthalmitis following renal stone lithotripsy is a serious and rare intraocular infection that may happen in healthy individuals without any risk factors. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - February 20, 2019 Category: Opthalmology Source Type: research

Evaluation of the etiology of persistent iritis after cataract surgery
ConclusionsRisk factors for persistent iritis after cataract surgery include being diabetic, of African American racial background, and pupil expansion device use. These patients can be better informed of the higher risk of prolonged inflammation in their post-operative course, and peri-operative management can be tailored accordingly. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - February 18, 2019 Category: Opthalmology Source Type: research

Injectable 0.19-mg fluocinolone acetonide intravitreal implant for the treatment of non-infectious uveitic macular edema
ConclusionsIn this small case series with long-term follow-up, treatment of non-infectious uveitic macular edema with the injectable fluocinolone acetonide implant was associated with improved central retinal thickness and corrected distance visual acuity and a manageable safety profile. The advantage of this device is the long-term drug release and the fact that it can be injected into the vitreous as a minor surgical procedure, which is in contrast to other treatment options. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - January 29, 2019 Category: Opthalmology Source Type: research

The ghost of the great imitator: prognostic factors for poor outcome in syphilitic uveitis
AbstractBackgroundSyphilitic uveitis is reemerging globally, may lead to any type of intraocular inflammation, and is potentially sight-threatening. We aim to characterize clinical features and prognostic factors in patients with syphilitic posterior uveitis.MethodsRetrospective chart review at two tertiary university-based referral centers in Brazil. Clinical data, laboratory results, and treatment outcomes were analyzed. Statistical analysis was performed using Fisher ’s exact test for categorical variables and Mann-WhitneyU test for continuous variables.ResultsForty-four patients (81 eyes) were consecutively diagn...
Source: Journal of Ophthalmic Inflammation and Infection - January 18, 2019 Category: Opthalmology Source Type: research

Blue light versus green light fundus autofluorescence in normal subjects and in patients with retinochoroidopathy secondary to retinal and uveitic diseases
ConclusionThe distribution and intensity of the AF signal differ in BAF and GAF and cannot be used interchangeably. In BAF, optic disc signal is always weaker than in other areas, which was not true for GAF where optic disc signal was stronger than fovea and hypoautofluorescent point in both groups. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - January 8, 2019 Category: Opthalmology Source Type: research

Urinary β2-microglobulin and disease activity in patients with tubulointerstitial nephritis and uveitis syndrome
ConclusionsU β2M correlate with uveitis activity and trend down over the course of TINU. Uβ2M may serve as a useful tool in determining where patients are in their systemic disease course. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - December 29, 2018 Category: Opthalmology Source Type: research

Syphilitic uveitis misdiagnosed as viral retinitis —a misleading history
ConclusionSyphilitic uveitis does not occur in primary disease and is common in secondary and early latent phase of syphilis. History given by the patient is often contributory however at times can be misleading. A high clinical suspicion and thorough investigation is necessary for the correct diagnosis and timely intervention in preventing loss of vision. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - December 4, 2018 Category: Opthalmology Source Type: research

Laser flare photometry: a cost-effective method for early detection of endophthalmitis after intravitreal injection of anti-VEGF agents
ConclusionLaser flare photometry is a cost-effective method of screening for early stage post-injection endophthalmitis. Values>  50 ph/ms 72-h post-injection should prompt immediate evaluation by an ophthalmologist. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - December 4, 2018 Category: Opthalmology Source Type: research

Clinical presentations, management outcomes, and diagnostic dilemma in Kocuria endophthalmitis
ConclusionsKocuria is a relatively rare cause of endophthalmitis often misdiagnosed asStaphylococcal endophthalmitis. Clinical presentation can be variable but favorable antibiotic susceptibility and appropriate timely management can result in acceptable visual and anatomic outcomes. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - November 20, 2018 Category: Opthalmology Source Type: research

Atypical white dot syndrome with choriocapillaris ischemia in a patient with latent tuberculosis
ConclusionAtypical WDS associated with choriocapillaris hypoperfusion may show features of multiple evanescent white dot syndrome and acute posterior multifocal placoid pigment epitheliopathy melting together. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - November 3, 2018 Category: Opthalmology Source Type: research

Comparative in vitro effectiveness of a novel contact lens multipurpose solution on Acanthamoeba castellanii
AbstractBackgroundA multipurpose contact lens cleaning solution (MPS) containing novel active ingredients under development was compared to two commercially available MPS solutions for effectiveness againstAcanthamoeba isolates.MethodsTheAcanthamoeba isolateA.castellanii was propagated for trophozoite or cyst-containing cultures for the purpose of assessment of effectiveness of each MPS. An alamar blue-based cellular respiration assay was used to assess effectiveness against trophozoites; Trypan blue hemocytometer-based microscopic counts measured cysticidal effects. To assess the general antimicrobial potency of each solu...
Source: Journal of Ophthalmic Inflammation and Infection - October 24, 2018 Category: Opthalmology Source Type: research

Acute multifocal retinitis: a retrospective review of 35 cases
ConclusionRickettsial disease was the most common cause of acute multifocal retinitis. Other identified causes included cat-scratch disease and syphilis, and a very small subset of patients was diagnosed with idiopathic multifocal retinitis. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - October 17, 2018 Category: Opthalmology Source Type: research

Discovery of tear biomarkers in children with chronic non-infectious anterior uveitis: a pilot study
ConclusionsTears contain similar cytokine profiles to aqueous humor in children with CAU and may be a clinically useful source of disease biomarkers. Tears from children with JIA-U also contain cytokines associated with inflammatory arthritis; furthermore, differential expression of other tear proteins as well may provide clues to intrinsic differences between JIA-U and I-CAU, despite their similar clinical phenotypes. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - October 16, 2018 Category: Opthalmology Source Type: research

Swept-source OCT in patients with multiple evanescent white dot syndrome
ConclusionsSS-OCT imaging allows a better visualization of the choriocapillaris, and its normal appearance in MEWDS may suggest that the outer retina and photoreceptors represent the primary site of inflammation. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - October 13, 2018 Category: Opthalmology Source Type: research

Endogenous endophthalmitis: a 9-year retrospective study at a tertiary referral hospital in Malaysia
ConclusionsThe visual prognosis of endogenous endophthalmitis is often poor, leading to blindness. As expected, gram-negative organisms specificallyKlebsiella pneumonia were the most common organisms isolated. Urinary tract infection was the main source of infection. Poor presenting visual acuity was significantly associated with grave visual outcomes. A high index of suspicion, early diagnosis, and treatment are crucial to salvage useful vision. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - October 11, 2018 Category: Opthalmology Source Type: research

Filamentous gram-negative bacteria masquerading as actinomycetes in infectious endophthalmitis: a review of three cases
ConclusionsGram-negative bacilli can develop abnormal morphology due to stress or sub-inhibitory antibiotic exposure, and it is important for ocular microbiologists and pathologists to be aware of this phenomenon to avoid misinterpretation that may lead to inappropriate treatment. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - October 11, 2018 Category: Opthalmology Source Type: research

An update on inflammatory choroidal neovascularization: epidemiology, multimodal imaging, and management
AbstractInflammatory choroidal neovascular membranes are challenging to diagnose and manage. A number of uveitic entities may be complicated by the development of choroidal neovascularization leading to a decrease in central visual acuity. In conditions such as punctate inner choroidopathy, development of choroidal neovascularization is extremely common and must be suspected in all cases. On the other hand, in patients with conditions such as serpiginous choroiditis, and multifocal choroiditis, it may be difficult to differentiate between inflammatory choroiditis lesions and choroidal neovascularization. Multimodal imaging...
Source: Journal of Ophthalmic Inflammation and Infection - September 12, 2018 Category: Opthalmology Source Type: research

Rituximab and bilateral HSV epithelial keratitis in a patient with mucous membrane pemphigoid
ConclusionsAlthough rituximab is a promising biologic agent for the treatment of autoimmune diseases, it bears the risk of reactivation of viral infections, including the onset of herpes simplex virus keratitis. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - August 23, 2018 Category: Opthalmology Source Type: research

Necrotising retinopathy-like lesions as a manifestation of ocular sarcoidosis
ConclusionNecrotising retinopathy-like lesions mimicking an infectious process or a lymphoproliferative disorder can be an atypical manifestation of ocular sarcoidosis. (Source: Journal of Ophthalmic Inflammation and Infection)
Source: Journal of Ophthalmic Inflammation and Infection - August 3, 2018 Category: Opthalmology Source Type: research