[Ochrobactrum anthropi catheter-related infection associated with superior vena cava syndrome].
Authors: Roussotte M, Gerfaud-Valentin M, Perpoint T, Dauwalder O, Sève P PMID: 31113703 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - May 24, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Lyme borreliosis and other tick-borne diseases. Guidelines from the French Scientific Societies (I): prevention, epidemiology, diagnosis.
Authors: Figoni J, Chirouze C, Hansmann Y, Lemogne C, Hentgen V, Saunier A, Bouiller K, Gehanno JF, Rabaud C, Perrot S, Caumes E, Eldin C, de Broucker T, Jaulhac B, Roblot F, Toubiana J, Sellal F, Vuillemet F, Sordet C, Fantin B, Lina G, Gocko X, Dieudonné M, Bodaghi B, Gangneux JP, Degeilh B, Partouche H, Lenormand C, Sotto A, Raffetin A, Monsuez JJ, Michel C, Boulanger N, Cathebras P, Tattevin P, endorsed by scientific societies Abstract Lyme borreliosis is transmitted en France by the tick Ixodes ricinus, endemic in metropolitan France. In the absence of vaccine licensed for use in humans, primary prevent...
Source: Medecine et Maladies Infectieuses - May 18, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Olecranon bursitis secondary to Mycobacterium europaeum infection in a patient receiving immunosuppressive drugs for rheumatoid arthritis.
Authors: Dutertre M, Delobel P, Marchou B, Boyer JF, Mougari F, Martin-Blondel G PMID: 31097371 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - May 18, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

HIV-infected patients aged above 75years.
Authors: Bernaud C, Sécher S, Michau C, Perre P, Fialaire P, Vatan R, Raffi F, Allavena C, Hitoto H Abstract BACKGROUND: Little data is available on HIV-infected patients aged over 75years. METHODS: A descriptive study of HIV-infected patients aged over 75years was conducted in six hospitals of the Pays de la Loire region, France. Socio-demographic, immuno-virological, and therapeutic characteristics were collected via an electronic medical record software (Nadis®). To assess frailty, a simplified geriatric assessment was conducted during an HIV routine visit. RESULTS: Among the 3965 patients fol...
Source: Medecine et Maladies Infectieuses - May 17, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Current practice of French health professionals regarding Japanese encephalitis vaccination.
Authors: Amat C, Bellanger AP, Bozon F, Léger R, Gbaguidi-Haore H, Marguet P Abstract OBJECTIVE: Japanese encephalitis (JE) is a rare but severe disease. It is a potential threat for people traveling to endemic areas. The risk of developing JE is low (
Source: Medecine et Maladies Infectieuses - May 17, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Molecular testing for respiratory pathogens in sickle cell disease adult patients presenting with febrile acute chest syndrome.
CONCLUSION: Using NAAT for the detection of respiratory pathogens in adults presenting with SCD slightly improved the microbiological diagnostic of febrile ACS, although respiratory infections are not the main etiological factor. PMID: 31088757 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - May 17, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Geotrichum capitatum fungemia in patients treated for acute leukemia.
Authors: Ben Neji H, Bchir M, Hamdoun M, Kallel A, Kallel K, Bahri O, Meddeb B PMID: 31079721 [PubMed - in process] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - May 14, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

"No glove, no love": Time to get priorities right again to prevent sexually transmitted infections?
"No glove, no love": Time to get priorities right again to prevent sexually transmitted infections? Med Mal Infect. 2019 Apr 20;: Authors: Caumes E PMID: 31014915 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - April 26, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Prospective study comparing the conventional and same-day strategies to diagnose pulmonary tuberculosis.
CONCLUSION: The same-day strategy seems to be a good alternative to the conventional strategy. PMID: 30982671 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - April 17, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Influenza infection and bacteremic pneumococcal pneumonia.
Authors: Blot M, Bruyère R, Chavanet P, Dalle F, Piroth L, Quenot JP, Charles PE PMID: 30961917 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - April 11, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Acute kidney injury in infective endocarditis: A retrospective analysis.
Authors: Gagneux-Brunon A, Pouvaret A, Maillard N, Berthelot P, Lutz MF, Cazorla C, Tulane C, Fuzellier JF, Verhoeven PO, Frésard A, Duval X, Lucht F, Botelho-Nevers E Abstract BACKGROUND: Acute kidney injury (AKI) is associated with high case fatality in infective endocarditis (IE), but epidemiological data on the frequency of AKI during IE is scarce. We aimed to describe the frequency and risk factors for AKI during the course of IE using Kidney Disease: Improving Global Outcomes consensual criteria. METHODS: Using the French hospital discharge database (French acronym PMSI), we retrospectively reviewe...
Source: Medecine et Maladies Infectieuses - April 10, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Antibiotic misuse: How to evaluate the costs?
CONCLUSIONS: Despite these limits, key factors for measuring antibiotic misuse (i.e., molecule choice, dosage) in relation to the costs (i.e., over/under prescription, hospital stay, staff remuneration) might serve as the basis for the development of a reference methodology to value the costs of misuse. The application of this methodology on identified situations of antibiotic misuse would help hospital decision-makers to justify resource allocation for implementing antimicrobial stewardship activities. PMID: 30954321 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - April 9, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Non-HACEK Gram-negative bacillus endocarditis.
Authors: Ertugrul Mercan M, Arslan F, Ozyavuz Alp S, Atilla A, Seyman D, Guliyeva G, Kayaaslan B, Sari S, Mutay Suntur B, Isik B, Mert A Abstract PATIENTS AND METHODS: Retrospective analysis of clinical data using 26 diagnosed non-HACEK Gram-negative infective endocarditis cases from nine hospitals in Turkey. RESULTS: Mean age of patients was 53 (28-84) years, with a 23% case fatality. Nineteen (73%) of the 26 patients had at least one predisposing factor. The presence of a central venous catheter was the most common predisposing factor (7/26 patients). Pseudomonasaeruginosa (7/26 patients) and Escherichiacoli ...
Source: Medecine et Maladies Infectieuses - April 4, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Bowel infarction due to mucormycosis in an immunocompromised patient.
Authors: Ezanno AC, Perrenot C, Guerci-Bresler A, Aoun O, Bresler L PMID: 30929970 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - April 3, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Escherichia coli endocarditis in an hemodialysis patient.
Authors: Vieille T, Winiszewski H, Chirouze C, Bertrand X, Fournier D PMID: 30926110 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - April 1, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Experience of three French centers in the management of more than 1,000 patients consulting for presumed Lyme Borreliosis.
Authors: Haddad E, Caumes E PMID: 30928181 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - April 1, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

[Vibrio cholerae non-O1/non-O139 otitis in metropolitan France].
Authors: Leroy AG, Lerailler F, Quilici ML, Bourdon S PMID: 30928182 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - April 1, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

High prevalence of Mycoplasma genitalium infection and macrolide resistance in patients enrolled in HIV pre-exposure prophylaxis program.
CONCLUSIONS: Because of a high level of macrolide resistance, a systematic search for M. genitalium macrolide resistance associated-mutations may be recommended in PrEP users before initiating the antibiotic therapy. PMID: 30914213 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - March 28, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Highly drug-resistant bacteria: Is intra- and inter-hospital communication optimal?
CONCLUSION: Efforts are still required in terms of communication for HDRB control. Sharing experiences and tools developed by hospitals may be beneficial for the entire hospital network. PMID: 30914214 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - March 28, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Factors of loss to follow-up during tuberculosis treatment in a low-incidence region.
CONCLUSION: The proportion of loss to follow-up was high. HIV infection was associated with a lower risk of loss to follow-up, likely to be due to more frequent support for compliance. PMID: 30890281 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - March 22, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Urinary tract infections in patients with neurogenic bladder.
Authors: Dinh A, Davido B, Duran C, Bouchand F, Gaillard JL, Even A, Denys P, Chartier-Kastler E, Bernard L Abstract Urinary tract infections (UTIs) in patients with neurogenic bladder are a major public health issue due to their high incidence and major consequences. Despite their frequency and potential severity, their physiopathology and management are poorly known. We provide a narrative literature review on the epidemiology, physiopathology, diagnostic criteria, microbiology, antimicrobial management, and prevention. UTIs among patients with neurogenic bladder are associated with high morbidity and healthcare ...
Source: Medecine et Maladies Infectieuses - March 21, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Management and prevention of imported malaria in children. 2019 update of the French guidelines.
Authors: Leblanc C, Vasse C, Minodier P, Mornand P, Naudin J, Quinet B, Siriez JY, Sorge F, de Suremain N, Thellier M, Kendjo E, Faye A, Imbert P Abstract Since the 2007 French guidelines on imported Falciparum malaria, the epidemiology, treatment, and prevention of malaria have changed considerably requiring guidelines for all Plasmodium species to be updated. Over the past decade, the incidence of imported malaria has decreased in all age groups, reflecting the decrease in the incidence of malaria in endemic areas. The rates of severe pediatric cases have increased as in adults, but fatalities are rare. The paras...
Source: Medecine et Maladies Infectieuses - March 21, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

A new combined predicting model using a non-invasive score for the assessment of liver fibrosis in patients presenting with chronic hepatitis B virus infection.
Authors: Ben Ayed H, Koubaa M, Yaich S, Rekik K, Ben Jemaa T, Maaloul I, Marrekchi C, Damak J, Ben Jemaa M Abstract OBJECTIVES: Several non-invasive markers have recently been proposed to predict liver fibrosis without percutaneous liver biopsy (PLB). We aimed to evaluate the performance of non-invasive scores and to highlight the value of a new combined score in the prediction of liver fibrosis in chronic hepatitis B (CHB) patients. PATIENTS AND METHODS: We performed a retrospective study of patients presenting with CHB who underwent PLB between 2008 and 2016. We calculated ASAT/Platelet Ratio Index (APRI), Fi...
Source: Medecine et Maladies Infectieuses - March 17, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Effect of antifungal exposure on the etiology of candidemia.
Authors: Hoarau G, Lemant J, Antok E, Gerardin P PMID: 30871817 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - March 17, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Effect of antifungal exposure on the etiology of candidemia.
Authors: Blot S PMID: 30871818 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - March 17, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Streamlined guidelines for antibiotic therapies are required for greater efficacy.
Authors: Roger PM, Michélangeli C, Girard D, Etienne P, Borredon G, Dautezac V, Keita-Perse O, Del Giudice P PMID: 30826173 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - March 5, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Meningococcal C vaccine coverage in France in infants, children, and adolescents.
CONCLUSIONS: VCRs are insufficient to reach herd immunity. Between 2011 and 2017 more than 100 deaths could have been avoided in France if optimal VCRs had been achieved. Faced with this vaccine strategy failure, the new vaccine recommendation at 5 months of age seems well-accepted. This recommendation and the implementation of infant mandatory vaccination in 2018 should have a major impact on IMD C incidence in this age group. PMID: 30826174 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - March 5, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

One-stage versus two-stage prosthesis replacement for prosthetic knee infections.
CONCLUSION: The one-stage replacement procedure for periprosthetic knee infection was associated with a similar healing frequency as the two-stage replacement procedure, and with better knee function. PMID: 30795868 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - February 25, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

PRISM study: Comparison of a nystatin-neomycin-polymyxin B combination with miconazole for the empirical treatment of infectious vaginitis.
CONCLUSION: The widespread use of NNP for several decades and its good efficacy and safety profile, as well as the frequent diagnostic uncertainties due to the various pathogens sustain the initiation of this broad-spectrum empirical treatment in infectious vaginitis. PMID: 30792037 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - February 24, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Multifactorial immunodeficiency in frail elderly patients: Contributing factors and management.
Authors: Tannou T, Koeberle S, Manckoundia P, Aubry R Abstract Immunodeficiency in the elderly is multifactorial. The analysis of etiological factors demonstrates the major role of immunosenescence and protein-energy malnutrition (PEM) with high prevalence deficiencies in micronutrients such as vitamin D, zinc, or vitamin E in people aged above 75 years. PEM contributes to the numerous consequences of frailty syndrome, and mainly to susceptibility to infections including fungal infections, which are usually observed in immunodeficient patients. Particular attention should thus be paid to these patients. However, th...
Source: Medecine et Maladies Infectieuses - February 22, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Retrospective study of pneumonia due to Panton-Valentine leukocidin-producing Staphylococcus aureus in Reunion.
CONCLUSION: Physicians should be aware of this infection during the flu season and quickly adapt the specific antibiotic treatment, including a drug inhibiting toxin production. As methicillin-resistant Staphylococcus aureus is very rarely observed in Reunion, physicians can still adapt the empirical treatment, without glycopeptides. PMID: 30765285 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - February 16, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Values of diagnostic tests for the various species of spirochetes.
Authors: Eldin C, Jaulhac B, Mediannikov O, Arzouni JP, Raoult D Abstract Bacteria of the Borrelia burgdorferi sensu lato complex, responsible for Lyme disease, are members of the spirochetes phylum. Diagnostic difficulties of Lyme disease are partly due to the characteristics of spirochetes as their culture is tedious or even impossible for some of them. We performed a literature review to assess the value of the various diagnostic tests of spirochetes infections of medical interest such as Lyme borreliosis, relapsing fever borreliae, syphilis, and leptospirosis. We were able to draw similarities between these fou...
Source: Medecine et Maladies Infectieuses - February 16, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Management of patients presenting with generalized musculoskeletal pain and a suspicion of Lyme disease.
Authors: Ranque-Garnier S, Eldin C, Sault C, Raoult D, Donnet A Abstract Lyme disease is caused by bacteria of the B. burgdorferi sensu lato complex, and can give polymorphic clinical manifestations that can affect several organs such as the skin, the central nervous system, or the joints. In recent years, patients' associations and physicians have been supporting the hypothesis that this infection would manifest as chronic generalized musculoskeletal pain symptoms, named "chronic Lyme disease". Fibromyalgia is a clinical presentation characterized by chronic generalized musculoskeletal pain with a m...
Source: Medecine et Maladies Infectieuses - February 16, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Ticks and tick-borne diseases.
Authors: Boulanger N, Boyer P, Talagrand-Reboul E, Hansmann Y Abstract Ticks are a major group of arthropod vectors, characterized by the diversity of pathogens they transmit, by their impact on human and animal health, and by their socioeconomic implication especially in countries of the Southern Hemisphere. In Europe, Ixodes is the most important tick due to its wide distribution in the ecosystems and the variety of transmitted pathogens, in particular Borrelia (responsible for Lyme borreliosis), but also the tick-borne encephalitis virus. Their increased presence in the environment since the beginning of the 20t...
Source: Medecine et Maladies Infectieuses - February 11, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Functional neuroimaging in patients presenting with somatoform disorders: A model for investigating persisting symptoms after tick bites and post-treatment Lyme disease syndrome?
Authors: Guedj E, Eldin C, Raoult D, Azorin JM, Belzeaux R Abstract Approximately 10% of patients presenting with Lyme disease experience fatigue, musculoskeletal pain, concentration disorders, or short-term memory deficits in the six months following treatment. This entity has been defined as post-Lyme disease syndrome or post-treatment Lyme disease syndrome. The pathophysiology of this syndrome is unknown, but neither persistence of the bacterium nor effectiveness of antibiotics are currently reported in the literature. The French High Council for Public Health (French acronym HCSP) has recently defined a new ent...
Source: Medecine et Maladies Infectieuses - February 11, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Post-bacterial infection chronic fatigue syndrome is not a latent infection.
Authors: Melenotte C, Drancourt M, Gorvel JP, Mège JL, Raoult D Abstract Post-infectious chronic fatigue syndrome is a public health problem. Etiologies and physiopathological mechanisms are unknown. Some viruses are known to be involved in post-infectious chronic fatigue syndrome, but the role of bacterial infection is still questioned, especially in cases of post-treatment Lyme disease syndrome where subjective symptoms are regularly attributed to the presence of the dormant bacterium without scientific evidence. However, the medical experience of recalcitrant infections, relapses, and reactivations questi...
Source: Medecine et Maladies Infectieuses - February 8, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

[Visceral leishmaniasis leading to macrophage activation syndrome].
Authors: Tazi S, Ouknane H, Lyagoubi M, Aoufi S PMID: 30704818 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - February 4, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

[Invasive pulmonary aspergillosis in an immunocompetent patient presenting with influenza infection].
Authors: Saint-Léger P PMID: 30709619 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - February 4, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Limitations of diagnostic tests for bacterial infections.
Authors: Eldin C, Parola P, Raoult D Abstract Lyme disease diagnosis is currently based on serology - an indirect diagnostic method - as laboratory cultures are fastidious. The only direct diagnostic method that can be useful with some specimens (cutaneous biopsies or aspiration fluid) is PCR. We aimed to detail the main limitations of serology and PCR testing in the diagnosis of bacterial infections. Limitations are supported by examples from the recent history of microbiology. The main limitation of bacterial serology is the presence of numerous cross-reactions due to many genes that are commo...
Source: Medecine et Maladies Infectieuses - January 30, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

[Isolated digestive localization of Hodgkin lymphoma in an HIV-infected patient, detected after hemophagocytic lymphohistiocytosis].
Authors: Romaru J, Lebrun D, Brunet A, Kheirallah S, Cousson J, Delmer A, Bani-Sadr F PMID: 30691919 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - January 30, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Characteristics of Enterobacter cloacae prosthetic joint infections.
CONCLUSION: Prosthetic joint infections due to E. cloacae usually occur early after the last prosthetic surgery, typically in patients with complex surgical and medical histories. The success rate seems to be increased when DAIR is associated with ciprofloxacin. PMID: 30691920 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - January 30, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Chronic Lyme disease: A scam that should be condemned!
Authors: Gentilini M, Bricaire F PMID: 30685081 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - January 29, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Impact of a long-term antibiotic stewardship program targeting fluoroquinolones in a French local hospital.
CONCLUSION: Setting up an antibiotic stewardship program in a local hospital can lead to a substantial reduction in FQ use and in E. coli resistance to FQs. It may also have a positive impact on community prescriptions. PMID: 30670316 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - January 25, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Lyme disease: Insight from social sciences.
This article is a selective literature review of social science works published on Lyme disease that draws on other articles published on similar health hazards. These works present Lyme borreliosis as an "archetypal" example of modern infectious risks. It is an "invisible" risk resulting from interactions between human activities, ecosystems, and pathogens. To tackle this risk, health authorities promote individual-based prevention measures. Perceptions of the general population should thus be better understood: different from the perceptions of experts, the general population's perceptions are sociall...
Source: Medecine et Maladies Infectieuses - January 19, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

The Lyme disease plan of the French Directorate General for Health.
Authors: Salomon J PMID: 30600111 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - January 3, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Impact of rapid diagnostic tests on the management of patients presenting with Enterobacteriaceae bacteremia.
Authors: Farfour E, Si Larbi AG, Cardot E, Limousin L, Mathonnet D, Cahen P, Vasse M, Lesprit P Abstract OBJECTIVE: Pathogens are usually identified from blood cultures using a two-step procedure: Gram staining on the day of bacterial growth (D0), followed by identification and susceptibility testing the following day (D1). We aimed to evaluate the use of rapid tests performed on D0 in patients presenting with Enterobacteriaceae bacteremia. PATIENTS AND METHODS: Patients with≥1 positive monomicrobial blood culture with Gram staining suggestive of an Enterobacteriaceae were prospectively included. Two success...
Source: Medecine et Maladies Infectieuses - January 2, 2019 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

A practical approach to tuberculosis diagnosis and treatment in liver transplant recipients in a low-prevalence area.
Authors: Bosch A, Valour F, Dumitrescu O, Dumortier J, Radenne S, Pages-Ecochard M, Chidiac C, Ferry T, Perpoint T, Miailhes P, Conrad A, Goutelle S, Ader F, Lyon TB study Group Abstract Solid organ transplant candidates/recipients are at risk of mycobacterial infections. Although guidelines on the management of latent tuberculosis infection and active tuberculosis are available for solid organ transplant recipients, limited guidance focuses on end-stage liver disease or liver transplant recipients who require management in a referral center. Therapeutic challenges arise from direct antituberculosis drug-related he...
Source: Medecine et Maladies Infectieuses - December 30, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Re-emergence of Corynebacterium diphtheriae.
We report two cases of Corynebacterium diphtheriae infection in a French hospital in 2016: a cutaneous infection with negative toxin testing in a French traveller, and a respiratory diphtheria carriage with positive toxin testing in an Afghan refugee diagnosed with pulmonary tuberculosis. The vaccination history of the Afghan patient could not be retrieved. PMID: 30583866 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - December 27, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Switching from abacavir/lamivudine plus nevirapine to abacavir/lamivudine/dolutegravir in virologically controlled HIV-infected adults (SWAD study).
Authors: Allavena C, Volteau C, André-Garnier E, Guimard T, Hall N, Khatchatourian L, Morrier M, Billaud E, Rodallec A, Reliquet V, Jovelin T, Le Guen L, Perré P, Grégoire M, Raffi F Abstract INTRODUCTION: The metabolic pathways of dolutegravir suggest a potential predator effect of nevirapine on dolutegravir pharmacokinetics and switching from a nevirapine- to a dolutegravir-containing regimen could lead to a lower and suboptimal exposure to dolutegravir several weeks after the switch in case of persistent inducer effect. PATIENTS AND METHOD: Prospective, pilot, single-arm, open-label, non...
Source: Medecine et Maladies Infectieuses - December 27, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Travel medicine consultation: An opportunity to improve coverage for routine vaccinations.
Authors: Aba YT, Gagneux-Brunon A, Andrillat C, Fouilloux P, Daoud F, Defontaine C, Lucht F, Botelho-Nevers E Abstract BACKGROUND: Travelers may be responsible for the spread of vaccine-preventable diseases upon return. Travel physicians and family physicians may play a role in checking and updating vaccinations before traveling. Our aim was to evaluate the vaccine coverage for mandatory and recommended vaccination in travelers attending a travel medicine clinic (TMC). METHODS: Vaccine coverage was measured using the current French immunization schedule as reference for correct immunization, in travelers provid...
Source: Medecine et Maladies Infectieuses - December 27, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research