Management of infective endocarditis and multidisciplinary approach.
CONCLUSION: The weekly EMM allows our facility to follow the European Society of Cardiology guidelines and to adapt the management of each patient to improve IE prognosis. PMID: 30029968 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - July 23, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Contribution of brain imaging to the diagnosis of intracranial tuberculoma and other brain lesions in patients presenting with miliary tuberculosis.
CONCLUSION: Among patients presenting with miliary TB who underwent brain imaging, more than 60% demonstrated cerebral involvement. Abnormal imaging could occur without any clinical nor CSF impairment. Systematically performing brain imaging in miliary TB patients could therefore be informative. PMID: 30017477 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - July 19, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Management of established pressure ulcer infections in spinal cord injury patients.
CONCLUSION: Management of infected pressure ulcers is a major concern in disabled patients already highly exposed to antimicrobial treatment and multidrug-resistant organisms colonization. Extensive data is required. PMID: 29937316 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - June 28, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Evaluation of broad-spectrum beta-lactam prescriptions (except carbapenems) in a French teaching hospital.
CONCLUSION: Broad-spectrum beta-lactams were usually well prescribed but the adequacy of treatment duration could be improved, especially by reinforcing the monitoring of prescriptions. PMID: 29941336 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - June 28, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Cerebrospinal fluid lactate concentration and bacterial encephalitis diagnosis.
Authors: Maillet M, De Broucker T, Mailles A, Bouzat P, Stahl JP, steering committee, investigator group Abstract OBJECTIVES: A French national study on infectious encephalitis enrolled 253 patients in 2007. Fifty-two per cent of patients had a proven etiological diagnosis; 16% had bacterial encephalitis. We aimed to assess the predictive value of CSF lactate concentration to diagnose bacterial encephalitis. PATIENTS AND METHODS: Patients from the 2007 cohort whose CSF lactate concentration was available were included. Clinical and biological features associated with a bacterial etiology were assessed using uni...
Source: Medecine et Maladies Infectieuses - June 20, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Head and neck squamous cell carcinoma in people living with HIV in France.
CONCLUSION: The prevalence of HNSCC is modest compared with other cancers in HIV-infected individuals. The prevalence of oropharynx carcinoma, a potentially HPV-related carcinoma, seems to increase over time. Even if tobacco may be an important contributor, the role of HPV in HIV-infected individuals presenting with HNSCC should be investigated. PMID: 29887186 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - June 13, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Characteristics and outcome of multidrug-resistant tuberculosis in a low-incidence area.
CONCLUSION: In western France, MDR-TB more frequently occurred in recent migrants from high-risk countries with a previous history of at-risk contact with other MDR-TB patients or previous TB treatment failure. PMID: 29887187 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - June 13, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Recurrent Enterococcus faecalis meningitis in a patient presenting with Strongyloides hyperinfection syndrome during HTLV-1-induced T-cell lymphoma.
Authors: Schein F, Fouillet L, Lutz MF, Daguenet E, Botelho-Nevers E, Cornillon J PMID: 29884325 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - June 10, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

[Capnocytophaga canimorsus bacterial meningitis].
Authors: Cabrol M, Le Bars H, Bailly P, Padelli M, Henry AS, Héry-Arnaud G, Beauruelle C PMID: 29884326 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - June 10, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Lactobacillus casei prosthetic joint infection.
Authors: de Seynes C, Dutronc H, Cremer P, Dupon M PMID: 29861314 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - June 6, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Of ignorance and blindness: The Lyme disease paradigm.
Authors: Raoult D PMID: 29805049 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - May 30, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Native aortic valve endocarditis due to Pseudomonas stutzeri in a 91-year-old woman.
Authors: Héquette-Ruz R, Charpentier A, Delabriere I, Loiez C, Guery B, Puisieux F, Beuscart JB PMID: 29807689 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - May 30, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Chickenpox: An update.
Authors: Lo Presti C, Curti C, Montana M, Bornet C, Vanelle P Abstract Despite its benign characteristics, chickenpox is a childhood disease responsible for complications and deaths, particularly in the high-risk population. VariZIG®, not commercialized in France, is a good alternative for seronegative individuals exposed to the virus and not eligible for vaccination. The efficacy of routine vaccination has been demonstrated with a decrease in chickenpox incidence and with the development of herd immunity. Over time, the protective antibody titer of vaccinated people decreases and can be maintained by two doses...
Source: Medecine et Maladies Infectieuses - May 24, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Pneumocystosis and quantitative PCR.
CONCLUSION: Our study confirms the diagnostic value of the qPCR in immunosuppressed patients, especially when the DE is negative. When the qPCR is˂56,000copies/mL, the result should be interpreted based on the clinical context and paraclinical examinations. PMID: 29789160 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - May 24, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Plague: Bridging gaps towards better disease control.
This article focused on the various aspects of the disease for which more tools and better understanding are required to better control the disease in endemic countries. PMID: 29773334 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - May 20, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Practice guidelines for the management of adult community-acquired urinary tract infections.
Authors: Caron F, Galperine T, Flateau C, Azria R, Bonacorsi S, Bruyère F, Cariou G, Clouqueur E, Cohen R, Doco-Lecompte T, Elefant E, Faure K, Gauzit R, Gavazzi G, Lemaitre L, Raymond J, Senneville E, Sotto A, Subtil D, Trivalle C, Merens A, Etienne M PMID: 29759852 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - May 17, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Plasmid-mediated colistin resistance gene mcr-1 in a clinical Escherichia coli isolate in the Indian Ocean Commission.
Authors: Leroy AG, Naze F, Dortet L, Naas T, Jaubert J PMID: 29753527 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - May 14, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Risk of falsely negative results with rapid HIV tests in HIV-infected patients.
Authors: Sayre N, Poupard M, Nivose PL, Khuong MA PMID: 29753528 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - May 14, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Candidemia in the intensive care unit: A 12-year retrospective cohort study in Reunion Island.
CONCLUSION: The epidemiology of candidemia in Reunion Island is characterized by the predominance of Candida albicans and by the relative importance of Candida tropicalis. This pattern corresponds to a model of epidemiological transition between the one usually observed in tropical areas and the one observed in temperate countries. PMID: 29753529 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - May 14, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Presence of qnr genes in ESBL-producing Enterobacteriaceae strains resistant to quinolones in Ouagadougou, Burkina Faso.
Authors: Kpoda DS, Guessennd N, Sangaré L, Dosso M, Traoré AS PMID: 29753530 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - May 14, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Prospective evaluation of the management of urinary tract infections in 134 French nursing homes.
CONCLUSION: Our study revealed multiple deficiencies in diagnosis, antibiotic choice, treatment duration, and reevaluation. PMID: 29747905 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - May 13, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

[Autochthonous dirofilariasis in the temporal muscle].
Authors: Fournier G, Morquin D, Goulabchand R, Tingaud C, de Boutray M PMID: 29731192 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - May 9, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Microbiology of French military casualties repatriated from overseas for an open traumatic injury.
CONCLUSIONS: Controlling the spread of ESBL-E is currently challenging for French Armed Forces. Despite any evidence of an epidemic clone, a high-level compliance with hygiene precautions is required throughout the chain of care to avoid cross contamination. PMID: 29709404 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - May 3, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

[Depression among patients affected by the human immunodeficiency virus].
Authors: Meziou O, Ghali F, Hamdi G, Khelifa E, Zalila H PMID: 29699829 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - April 29, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Prevalence and risk factors for low bone mineral density in antiretroviral therapy-naive HIV-infected young men.
CONCLUSIONS: We observed a high prevalence of low BMD in our ART-naive cohort of young men. Risk factors associated with low Z-scores were those usually observed in HIV-infected individuals (low BMI, current smoking and CD4+ cell count) or linked to endocrine hormone levels (estradiol, IGF-1). PMID: 29699830 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - April 29, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Infectious sacroiliitis: Retrospective analysis of 18 case patients.
CONCLUSION: Infectious sacroiliitis is a complex pathology requiring precise clinical examination for a rapid diagnosis. The outcome is usually favorable. PMID: 29692328 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - April 27, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Trimethoprim susceptibility in E. coli community-acquired urinary tract infections in France.
CONCLUSION: The results support trimethoprim as a second-line therapy based on antibiotic susceptibility testing results. We confirm that trimethoprim and cotrimoxazole susceptibility rates are very close. PMID: 29673879 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - April 22, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

French hospital discharge database (PMSI) and bacterial resistance: Is coding adapted to hospital epidemiology?
CONCLUSION: The cartography of bacterial infections cannot be developed using the data of the current PMSI coding. These results underline the need to improve the coding of PMSI data for its use as a complementary tool of epidemiological surveillance of bacterial infections. PMID: 29673880 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - April 22, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Vitamin D supplementation, bone turnover, and inflammation in HIV-infected patients.
CONCLUSIONS: Vitamin D supplementation decreases the risk of hypovitaminosis D but does not decrease the risk of inflammation nor bone turnover, unless normal 25-OH vitamin D levels are reached. PMID: 29661598 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - April 19, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

An unforeseen complication of a folk remedy for joint pain.
Authors: Assous MV, Schwartz Y, Ben-Chetrit E PMID: 29656840 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - April 17, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

From phaeohyphomycosis to disseminated chromoblastomycosis: A retrospective study of infections caused by dematiaceous fungi.
CONCLUSION: Infections caused by dematiaceous fungi are rare. Medullary and brain localizations are extremely rare, especially for chromoblastomycosis. Cutaneous manifestations of phaeohyphomycosis are varied; diagnosis is thus more difficult. It is therefore important, when confronted with a chronic tumor-like lesion in endemic areas, to perform a biopsy for pathology and fungal culture. While surgical excision is not always sufficient, medical treatment of these infections is not standardized, but relies on an azole, which can be associated with another antifungal agent. PMID: 29656841 [PubMed - as supplied by publis...
Source: Medecine et Maladies Infectieuses - April 17, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Incidence of all-cause adult community-acquired pneumonia in primary care settings in France.
CONCLUSIONS: Using a pragmatic case definition of CAP patients, this study estimated an incidence of 4.7 per 1000 persons per year that is in the lower half of the range of estimated incidences reported in primary care settings in industrialized countries. PMID: 29656842 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - April 17, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Erysipelothrix rhusiopathiae knee prosthesis infection.
Authors: Gazeau P, Rezig S, Quaesaet L, Williams T, Tande D, Ansart S PMID: 29656843 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - April 17, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Maribavir, brincidofovir and letermovir: Efficacy and safety of new antiviral drugs for treating cytomegalovirus infections.
This article summarizes the current state of the prevention and treatment of CMV infections as well as data of investigational drugs in clinical development. PMID: 29650261 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - April 14, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Interpreting carbapenem susceptibility testing results for Pseudomonas aeruginosa.
CONCLUSION: The accuracy of disc diffusion using CA-SFM guidelines appears unsatisfactory for all three carbapenems justifying guideline update for P. aeruginosa and carbapenems. PMID: 29628176 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - April 10, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Cerebrospinal fluid monocytes in bacterial meningitis, viral meningitis, and neuroborreliosis.
Authors: Martinot M, Greigert V, Souply L, Rosolen B, De Briel D, Mohseni Zadeh M, Kaiser JD Abstract OBJECTIVE: Cerebrospinal fluid (CSF) leukocytes analysis is commonly used to diagnose meningitis and to differentiate bacterial from viral meningitis. Interpreting CSF monocytes can be difficult for physicians, especially in France where lymphocytes and monocytes results are sometimes pooled. PATIENTS AND METHODS: We assessed SF monocytes in patients presenting with microbiologically confirmed meningitis (CSF leukocyte count>10/mm3 for adults or>30/mm3 for children
Source: Medecine et Maladies Infectieuses - April 10, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome due to ethambutol.
Authors: Gest N, Ingen-Housz-Oro S, Gener G, Bellanger M, Henn A, Gallien S, Flateau C PMID: 29602678 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - April 2, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Investigation of an outbreak of monkeypox in an area occupied by armed groups, Central African Republic.
CONCLUSION: The annual number of monkeypox outbreaks increases in the Central African Republic with severe presentations and a high case fatality especially in children. Reinforcing the surveillance and characterization of circulating strains will provide information on the need for vaccine production. PMID: 29573840 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - March 28, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Mycobacterium canettii pulmonary tuberculosis in an immunocompetent patient.
Authors: Conan PL, Charton F, Le Floch H, Grand B, Soler C, Aletti M, Margery J, Rivière F PMID: 29567346 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - March 24, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Respiratory syncytial virus infection in elderly adults.
Authors: Haber N Abstract Respiratory syncytial virus (RSV) is a major cause of severe lower respiratory tract infections in infants and young children. Reinfections are common throughout adult life with more severe presentations occurring in immunocompromised individuals, subjects with underlying high-risk cardiopulmonary diseases, and in the elderly. There is now a significant body of literature indicating that the impact of RSV in elderly adults is similar to that of non-pandemic influenza, both in the community and in nursing homes. Clinical manifestations of RSV infections are similar to those caused by other ...
Source: Medecine et Maladies Infectieuses - March 21, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Travel and acquisition of multidrug-resistant Enterobacteriaceae.
Authors: Armand-Lefèvre L, Andremont A, Ruppé E Abstract Bacterial resistance to antibiotics is considered a major threat to health. Enterobacteriaceae have increasingly become resistant to antibiotics through the acquisition and dissemination of extended-spectrum beta-lactamases (ESBL) that confer resistance to most beta-lactams. While ESBL-producing Enterobacteriaceae were formerly restricted to hospitals, they have now spread to community settings, especially in developing countries. The tremendous expansion of international travels contributed to the importation of multidrug-resistant Enterobacter...
Source: Medecine et Maladies Infectieuses - March 21, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

[Sporotrichosis in France].
Authors: Larsabal M, Gabriel F, Pajaniapadeatchy E, Rougeron A, Accoceberry I, Garcia-Hermoso D, Saunier A PMID: 29555122 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - March 21, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Key features of bone and joint infections following the implementation of reference centers in France.
CONCLUSIONS: BJI prevalence highly increased in France. Complex BJI prevalence assessment is complicated by the absence of clinical consensus and probable undercoding. A validation of clinical case definition of complex BJI is required. PMID: 29526340 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - March 14, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Access to artemisinin-based combination therapies and other anti-malarial drugs in Kinshasa.
CONCLUSION: Artemisinin-based combination therapies were widely available in the private pharmacies of Kinshasa. However, the private sector does not guarantee the use of nationally recommended anti-malarial drugs nor does it give priority to quality-assured anti-malarial drugs. These practices contribute to the risk of emergence and spread of resistance to anti-malarial drugs and to increasing treatment costs. PMID: 29530387 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - March 14, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Emergence of plasmid-mediated colistin resistance (mcr-1) among Enterobacteriaceae strains: Laboratory detection of resistance and measures to control its dissemination.
This article describes the epidemiological context of the discovery of this emergence in France and worldwide, the resistance mechanisms, the microbiological methods of routine laboratory detection and the level of hygiene measures to implement in French facilities. PMID: 29475568 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - February 26, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Use of telemedicine in the management of infectious diseases.
Authors: Gras G Abstract Communication technologies have invaded our daily lives. Several studies have assessed these technologies in the management of infectious diseases (mainly HIV). Weekly short text messages and real-time compliance monitoring assessed in HIV patients are both associated with higher compliance in low-income countries. Virtual consultations to monitor stable chronic HIV patients or tuberculosis treatment in high-income countries appear to be acceptable and efficient. Although assessed in small studies, virtual monitoring seems to reinforce the doctor-patient relationship and the relation betwee...
Source: Medecine et Maladies Infectieuses - February 19, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Borrelia burgdorferi sl and tick-borne encephalitis virus coinfection in Eastern France.
Authors: Boyer PH, Kieffer P, de Martino SJ, Zilliox L, Vogel JY, Jaulhac B, Hansmann Y PMID: 29449048 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - February 18, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Extended-spectrum β-lactamase-producing Enterobacteriaceae, national study of antimicrobial treatment for pediatric urinary tract infection.
CONCLUSIONS: Antimicrobial treatment for ESBL-producing UTI greatly varies, and carbapenems are excessively prescribed. Specific guidelines for ESBL infections are required. PMID: 29449049 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - February 18, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

HIV preexposure prophylaxis: An essential, safe and effective prevention tool for sexual health.
Authors: Siguier M, Molina JM Abstract Preexposure prophylaxis of HIV with antiretroviral drugs is a prevention tool available in France since 2016, combined with the prevention methods already used (condoms, post-exposure treatment, rapid treatment of diagnosed HIV infections, etc.). It is targeted at populations at high risk of HIV infection, especially men who have sex with men, for whom traditional prevention methods are insufficient. We collected clinical research data, which resulted in the launch of preexposure prophylaxis in the United States and then elsewhere in the world, safety, tolerability and cost da...
Source: Medecine et Maladies Infectieuses - February 14, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Use of artesunate in non-malarial indications.
Authors: Raffetin A, Bruneel F, Roussel C, Thellier M, Buffet P, Caumes E, Jauréguiberry S Abstract INTRODUCTION: Artesunate and other artemisinin derivatives are used in various infectious and non-infectious diseases. We aimed to analyze available data on artesunate and artemisinin derivatives activity in humans and their potential clinical benefits in non-malarial indications. MATERIAL AND METHODS: Literature review performed on PubMed and the Cochrane Library databases using the PRISMA method. We analyzed studies published in English from January 2008 to August 2017 using the same indicators of drug e...
Source: Medecine et Maladies Infectieuses - February 11, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research