Ventilator-induced Lung Injury Promotes Inflammation within the Pleural Cavity
Am J Respir Cell Mol Biol. 2024 May 20. doi: 10.1165/rcmb.2023-0332OC. Online ahead of print.ABSTRACTMechanical ventilation contributes to the morbidity and mortality of patients in Intensive Care, likely through the exacerbation and dissemination of inflammation. Despite its proximity to the lungs and exposure to physical forces, little attention has been paid to the potential of the pleural cavity as an inflammatory source during ventilation. Here we investigate the pleural cavity as a novel site of inflammation during ventilator-induced lung injury. Mice were subjected to low or high tidal volume ventilation strategies ...
Source: Respiratory Care - May 20, 2024 Category: Respiratory Medicine Authors: Rhianna F Baldi Marissa W Koh Chubicka Thomas Tomasz Sabbat Bincheng Wang Stefania Tsatsari Kieron Young Alexander Wilson-Slomkowski Sanooj Soni Kieran P O'Dea Brijesh V Patel Masao Takata Michael R Wilson Source Type: research

Corrigendum: Severe Community-Acquired Pneumonia: Noninvasive Mechanical Ventilation, Intubation, and HFNT
Semin Respir Crit Care Med. 2024 Apr;45(2):e1. doi: 10.1055/s-0044-1786980. Epub 2024 May 20.NO ABSTRACTPMID:38768644 | DOI:10.1055/s-0044-1786980 (Source: Respiratory Care)
Source: Respiratory Care - May 20, 2024 Category: Respiratory Medicine Authors: Miquel Ferrer Gennaro De Pascale Eloisa S Tanzarella Massimo Antonelli Source Type: research

Sexual activity and Respiratory Disease: a systematic review
CONCLUSIONS: Sexual activity, depending on age and individual specific conditions, is a fundamental driver of overall health, and therefore of lung health.PMID:38768665 | DOI:10.1016/j.rmed.2024.107665 (Source: Respiratory Care)
Source: Respiratory Care - May 20, 2024 Category: Respiratory Medicine Authors: Joan B Soriano Francesca Polverino Source Type: research

Persistent Glossopharyngeal Nerve Respiratory Discharge Patterns after Ponto-Medullary Transection
In conclusion respiratory GPNA reflects FNA and HNA which implies similar function in controlling upper airway patency during breathing. That GPNA preserved its pre-inspiratory/inspiratory discharge pattern in relation PNA after pontomedullary transection suggest that GPNA premotor circuits may have a different anatomical distribution compared HNA and FNA and thus may therefore hold a unique role in in preserving airway patency.PMID:38768741 | DOI:10.1016/j.resp.2024.104281 (Source: Respiratory Care)
Source: Respiratory Care - May 20, 2024 Category: Respiratory Medicine Authors: Gijnovefa Kola Eriko Hamada Rishi R Dhingra Frank J Jacono Thomas E Dick Denise Dewald Kingman P Strohl Thomaz Fleury-Curado Mathias Dutschmann Source Type: research

< em > TOLLIP < /em > Single Nucleotide Polymorphism and Antimicrobial Treatment Effect in Idiopathic Pulmonary Fibrosis
Am J Respir Crit Care Med. 2024 May 19. doi: 10.1164/rccm.202312-2224LE. Online ahead of print.NO ABSTRACTPMID:38762791 | DOI:10.1164/rccm.202312-2224LE (Source: Respiratory Care)
Source: Respiratory Care - May 19, 2024 Category: Respiratory Medicine Authors: William Whalen Kristin Berger John S Kim Will Simmons Shwu-Fan Ma Robert J Kaner Fernando J Martinez Kevin J Anstrom Helen Parfrey Toby Maher Matt Hammond Allan B Clark David Thickett R Gisli Jenkins Andrew M Wilson Imre Noth Source Type: research

Impact of the COVID-19 Pandemic on a Program to Screen for Subclinical Familial Pulmonary Fibrosis
Am J Respir Crit Care Med. 2024 May 19. doi: 10.1164/rccm.202401-0034LE. Online ahead of print.NO ABSTRACTPMID:38762792 | DOI:10.1164/rccm.202401-0034LE (Source: Respiratory Care)
Source: Respiratory Care - May 19, 2024 Category: Respiratory Medicine Authors: Margaret L Salisbury Cheryl R Markin Tisra H Fadely Adam R Guttentag Jonathan A Kropski Timothy S Blackwell Source Type: research

Potential Diaphragm Muscle Weakness-related Dyspnea Persists Two Years after COVID-19 and Could Be Improved by Inspiratory Muscle Training: Results of an Observational and an Interventional Trial
CONCLUSIONS: This study is the first to identify a potential treatment for persisting exertional dyspnea in long COVID, and provide a possible pathophysiological explanation for the treatment benefit. This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License 4.0 (http://creativecommons.org/licenses/by-nc-nd/4.0/).PMID:38763165 | DOI:10.1164/rccm.202309-1572OC (Source: Respiratory Care)
Source: Respiratory Care - May 19, 2024 Category: Respiratory Medicine Authors: Jens Spiesshoefer Binaya Regmi Mehdi Senol Benedikt J örn Oscar Gorol Mustafa Elfeturi Stephan Walterspacher Alberto Giannoni Florian Kahles Rainer Gloeckl Michael Dreher Source Type: research

Impact of High Dose Early Mobilization on Outcomes for Patients with Diabetes: A Secondary Analysis of the TEAM Trial
CONCLUSIONS: In this secondary analysis of the TEAM trial, in patients with diabetes, a high dose early mobilization strategy did not significantly decrease the number of days alive and out of hospital at day 180 but it increased 180-day mortality.PMID:38763167 | DOI:10.1164/rccm.202312-2289OC (Source: Respiratory Care)
Source: Respiratory Care - May 19, 2024 Category: Respiratory Medicine Authors: Ary Serpa Neto Michael Bailey Daniel Seller Alicia Agli Rinaldo Bellomo Kathy Brickell Tessa Broadley Heidi Buhr Belinda J Gabbe Doug W Gould Meg Harrold Alisa M Higgins Sally Hurford Theodore J Iwashyna Alistair D Nichol Jeffrey J Presneill Stefan J Scha Source Type: research

The Risk of Secondary Spontaneous Pneumothorax in Patients with Chronic Obstructive Pulmonary Disease in Taiwan
CONCLUSION: Our study revealed an elevated risk of SSP in patients with COPD. It has also been suggested that COPD patients with comorbidities, such as atrial fibrillation, congestive heart failure, coronary artery disease, diabetes mellitus, hypertension, and cancer, have an increased risk of developing SSP.PMID:38763446 | DOI:10.1016/j.rmed.2024.107672 (Source: Respiratory Care)
Source: Respiratory Care - May 19, 2024 Category: Respiratory Medicine Authors: Kuang-Ming Liao Chong-Chi Chiu Hsueh-Yi Lu Source Type: research

Empowering Caregivers of Children with Bronchiolitis Obliterans: The Effectiveness of an Internet-based Follow-up Platform
CONCLUSIONS: the Internet-based follow-up platform can empower caregivers in enhancing effective family management, improving medication compliance in children with BO, and relieving patients' clinical symptoms.TRIAL REGISTRATION: Chinese Clinical Trials Registry of ChiCTR2200065121 (04/28/2022).PMID:38763447 | DOI:10.1016/j.rmed.2024.107673 (Source: Respiratory Care)
Source: Respiratory Care - May 19, 2024 Category: Respiratory Medicine Authors: Huayan Liu Qingqing Song Min Yi Xiaoyan Tan Yanping Chen Jianhui Xie Xuandong Wei Hongtao Chen Lina Zhong Xia Wu Kewei Wang Source Type: research

Early Mobilization in the ICU and Diabetes: A Bittersweet Concoction?
Am J Respir Crit Care Med. 2024 May 19. doi: 10.1164/rccm.202405-0964ED. Online ahead of print.NO ABSTRACTPMID:38763507 | DOI:10.1164/rccm.202405-0964ED (Source: Respiratory Care)
Source: Respiratory Care - May 19, 2024 Category: Respiratory Medicine Authors: Matthew F Mart E Wesley Ely Source Type: research

< em > TOLLIP < /em > Single Nucleotide Polymorphism and Antimicrobial Treatment Effect in Idiopathic Pulmonary Fibrosis
Am J Respir Crit Care Med. 2024 May 19. doi: 10.1164/rccm.202312-2224LE. Online ahead of print.NO ABSTRACTPMID:38762791 | DOI:10.1164/rccm.202312-2224LE (Source: Respiratory Care)
Source: Respiratory Care - May 19, 2024 Category: Respiratory Medicine Authors: William Whalen Kristin Berger John S Kim Will Simmons Shwu-Fan Ma Robert J Kaner Fernando J Martinez Kevin J Anstrom Helen Parfrey Toby Maher Matt Hammond Allan B Clark David Thickett R Gisli Jenkins Andrew M Wilson Imre Noth Source Type: research

Impact of the COVID-19 Pandemic on a Program to Screen for Subclinical Familial Pulmonary Fibrosis
Am J Respir Crit Care Med. 2024 May 19. doi: 10.1164/rccm.202401-0034LE. Online ahead of print.NO ABSTRACTPMID:38762792 | DOI:10.1164/rccm.202401-0034LE (Source: Respiratory Care)
Source: Respiratory Care - May 19, 2024 Category: Respiratory Medicine Authors: Margaret L Salisbury Cheryl R Markin Tisra H Fadely Adam R Guttentag Jonathan A Kropski Timothy S Blackwell Source Type: research

Potential Diaphragm Muscle Weakness-related Dyspnea Persists Two Years after COVID-19 and Could Be Improved by Inspiratory Muscle Training: Results of an Observational and an Interventional Trial
CONCLUSIONS: This study is the first to identify a potential treatment for persisting exertional dyspnea in long COVID, and provide a possible pathophysiological explanation for the treatment benefit. This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License 4.0 (http://creativecommons.org/licenses/by-nc-nd/4.0/).PMID:38763165 | DOI:10.1164/rccm.202309-1572OC (Source: Respiratory Care)
Source: Respiratory Care - May 19, 2024 Category: Respiratory Medicine Authors: Jens Spiesshoefer Binaya Regmi Mehdi Senol Benedikt J örn Oscar Gorol Mustafa Elfeturi Stephan Walterspacher Alberto Giannoni Florian Kahles Rainer Gloeckl Michael Dreher Source Type: research

Impact of High Dose Early Mobilization on Outcomes for Patients with Diabetes: A Secondary Analysis of the TEAM Trial
CONCLUSIONS: In this secondary analysis of the TEAM trial, in patients with diabetes, a high dose early mobilization strategy did not significantly decrease the number of days alive and out of hospital at day 180 but it increased 180-day mortality.PMID:38763167 | DOI:10.1164/rccm.202312-2289OC (Source: Respiratory Care)
Source: Respiratory Care - May 19, 2024 Category: Respiratory Medicine Authors: Ary Serpa Neto Michael Bailey Daniel Seller Alicia Agli Rinaldo Bellomo Kathy Brickell Tessa Broadley Heidi Buhr Belinda J Gabbe Doug W Gould Meg Harrold Alisa M Higgins Sally Hurford Theodore J Iwashyna Alistair D Nichol Jeffrey J Presneill Stefan J Scha Source Type: research