Protein and Polysaccharide Recovery from Shrimp Wastes by Natural Deep Eutectic Solvent Mediated Subcritical Water Hydrolysis for Biodegradable Film
In this study, the composite films were produced using the solution casting method. Moreover, the combined effect of ultrasound pretreatments (UPT) and natural deep eutectic solvents (NADES) was investigated as extraction media, to determine their potential impact on shrimp waste subcritical water hydrolysis (SWH). Shrimp shells were submitted to UPT in NADES solution, followed by SWH at different temperatures ranging from 150 to 230 °C under 3 MPa for 20 min. Then, the physiochemical properties and bioactivities of the hydrolysates were assessed to determine their suitability for use in biodegradable packaging films. Add...
Source: Marine Biotechnology - May 3, 2024 Category: Biotechnology Authors: Md Sadek Ali Vikash Chandra Roy Jin-Seok Park Ahmed Redwan Haque Jin Hong Mok Wei Zhang Byung-Soo Chun Source Type: research

Zinc oxide application alleviates arsenic-mediated oxidative stress via physio-biochemical mechanism in rice
Environ Sci Pollut Res Int. 2024 May 3. doi: 10.1007/s11356-024-33380-0. Online ahead of print.ABSTRACTArsenic (As) pollution in cultivated soils poses a significant risk to the sustainable growth of agriculture and jeopardizes food security. However, the mechanisms underlying how zinc (Zn) regulates the toxic effects induced by As in plants remain poorly understood. Hence, this study aimed to explore the potential of ZnO as an effective and environmentally friendly amendment to alleviate As toxicity in rice, thereby addressing the significant risk posed by As pollution in cultivated soils. Through a hydroponic experiment,...
Source: Environmental Science and Pollution Research International - May 3, 2024 Category: Environmental Health Authors: Sanaullah Jalil Muhammad Mudassir Nazir Mohamed A Eweda Faisal Zulfiqar Temoor Ahmed Muhammad Noman Muhammad A U Asad Kadambot H M Siddique Xiaoli Jin Source Type: research

Effect of ruthenium(II) complexes on MDA-MB-231 cells and lifespan/tumor growth in gld-1mutant, Daf-16 TF and stress productive genes: A perspective study
J Inorg Biochem. 2024 Apr 28;257:112580. doi: 10.1016/j.jinorgbio.2024.112580. Online ahead of print.ABSTRACTPincer type coumarin based N-substituted semicarbazone ligands HL1-4 and their corresponding ruthenium(II) complexes (1-4) were synthesized, analyzed and confirmed by various spectro analytical techniques. The molecular structure of the ligand HL3 and complex 3 was confirmed by single crystal X-ray diffraction analysis. The stoichiometry of complexes 1, 2 and 4 was confirmed by high resolution mass spectroscopy (HRMS). The binding affinity of the compounds with CT-DNA (Calf Thymus DNA) and BSA (Bovine Serum Albumin)...
Source: Journal of Inorganic Biochemistry - May 3, 2024 Category: Biochemistry Authors: S Nandhini G Thiruppathi M Ranjani H Pushmann M Ravi P Sundararaj R Prabhakaran Source Type: research

Camellia Oleifera shells derived nano cellulose crystals conjugated with gallic acid as a sustainable Pickering emulsion stabilizer
This study extracted the nano cellulose crystals (NCs) from Camellia Oleifera shells, and their gallic acid (GA) conjugates were synthesized by free-radical grafting. Pickering emulsions were prepared using NCs 1 %, 1.5 %, 2.5 %, and gallic acid conjugates NC-GA1, NC-GA2, and NC-GA3 as stabilizers. The obtained nano cellulose crystals exhibited 18-25 nm, -40.01 ± 2.45 size, and zeta potential, respectively. The contact angle of 83.4° was exhibited by NC-GA3 conjugates. The rheological, interfacial, and microstructural properties and stability of the Pickering emulsion were explored. NC-GA3 displayed the highest absorptio...
Source: International Journal of Biological Macromolecules - May 3, 2024 Category: Biochemistry Authors: Miral Javed Yanqun Xu Haixin Sun Huang Hao Dong Li Anam Matloob Yan Xiaowei Zisheng Luo Source Type: research

Effects of PVA and yerba mate extract on extruded films of carboxymethyl cassava starch/PVA blends for antioxidant and mechanically resistant food packaging
This study investigates the impact of incorporating different concentrations of polyvinyl alcohol (PVA) and yerba mate extract as a natural antioxidant into carboxymethyl cassava starch films to possibly use as active degradable packaging to enhance food shelf life. Films with starch and PVA blends (SP) at different ratios (SP radios of 100:0, 90:10, 80:20 and 70:30) with and without yerba mate extract (Y) were successfully produced through extrusion and thermoforming. The incorporation of up to 20 wt% PVA improved starch extrusion processing and enhanced film transparency. PVA played a crucial role in improving the hydrop...
Source: International Journal of Biological Macromolecules - May 3, 2024 Category: Biochemistry Authors: Luca G ómez-Bachar Maia Vilcovsky Paula Gonz ález-Seligra Luc ía Famá Source Type: research

Berberis integerrima bioactive molecules loaded in chitosan-based electrospun nanofibers for soybean oil oxidative protection
This study underscores the potential of harnessing natural antioxidants from Berberis integerrima in nanofibers to enhance the quality and safety of soybean oil.PMID:38702247 | DOI:10.1016/j.ijbiomac.2024.131692 (Source: International Journal of Biological Macromolecules)
Source: International Journal of Biological Macromolecules - May 3, 2024 Category: Biochemistry Authors: Mohsen Asghari Mohammad Ali Sahari Seyed Jalal Kia Atefeh Tavakoli Mohsen Barzegar Source Type: research

Concentration-Dependent Effects of Boric Acid on Osteogenic Differentiation of Vascular Smooth Muscle Cells
Biol Trace Elem Res. 2024 May 3. doi: 10.1007/s12011-024-04204-6. Online ahead of print.ABSTRACTVascular calcification can be triggered by oxidative stress and inflammation. Although boron possesses antioxidant and anti-inflammatory properties, its effect on osteogenic differentiation of vascular smooth muscle cells (VSMCs) has yet to be examined. Therefore, we aimed to investigate the effect of boric acid (BA), the main form of boron in body fluids, on the osteogenic differentiation of VSMCs. Following the isolation of VSMCs, the effects of BA on cell proliferation were determined by MTT. The impact of various BA concentr...
Source: Biological Trace Element Research - May 3, 2024 Category: Biology Authors: Osama Al Khalif G ülay Sezer Source Type: research

Elemental and Radiological Characterisation of Arbutus unedo L. Leaves and Tea: Impact of Preparation Method on Nutritional Risk/Benefit
Biol Trace Elem Res. 2024 May 3. doi: 10.1007/s12011-024-04201-9. Online ahead of print.ABSTRACTThe aim of this study was to characterise the elemental and radiological composition of strawberry tree (Arbutus unedo L.) leaves and tea preparations and compare it with commercial Uvin H herbal mixture, widely used in treatment of urinary tract infections. The concentration of 17 elements and the activity concentration of selected radionuclides were measured in strawberry tree leaves/Uvin H herbal mixture, as well as in herbal tea prepared by infusion or decoction of leaves for 5 or 10 min. In both leaves and tea preparations,...
Source: Biological Trace Element Research - May 3, 2024 Category: Biology Authors: Blanka Tariba Lovakovi ć Davor Ra šeta Maja Lazarus Karlo Jurica Tanja Živković Semren Andreja Juri č Aleksandra Drami ćanin Branko Petrinec Aleksandar Bulog Irena Br čić Karačonji Source Type: research

Kefir mitigates renal damage caused by zearalenone in female Wistar rats by reducing oxidative stress
Toxicon. 2024 May 1:107743. doi: 10.1016/j.toxicon.2024.107743. Online ahead of print.ABSTRACTThe estrogen-like mycotoxin zearalenone (ZEA) was popularly occurred in several food and feeds, posing threats to human and animal health. ZEA induced renal toxicity and caused oxidative stress. In the current study, the protecting effect of kefir administration against ZEA-induced renal damage in rats was explored. Rats were divided into 4 groups, each consisting of 5 animals. For the initial 7 days, they were orally administered sterile milk (200 μL/day). Subsequently, during the second week, the groups were exposed to kefir (2...
Source: Toxicon - May 3, 2024 Category: Toxicology Authors: Fadia Ben Taheur Chalbia Mansour Sihem Safta Skhiri Habib Chaaban Mourad Jridi Nahed Fakhfakh Nacim Zouari Source Type: research

Asiatic acid rescues intestinal tissue by suppressing molecular, biochemical, and histopathological changes associated with the development of ulcerative colitis
In conclusion, AA could improve the antioxidative status and attenuate the inflammatory and apoptotic challenges associated with UC.PMID:38699907 | DOI:10.1042/BSR20232004 (Source: Bioscience Reports)
Source: Bioscience Reports - May 3, 2024 Category: Biomedical Science Authors: Maha S Lokman Rami Kassab Fatma A M Salem Gehad E Elshopakey Akram Hussein Ahmed A Aldarmahi Abdulrahman Theyab Khalid J Alzahrani Khalid E Hassan Khalaf F Alsharif Ashraf Albrakati Jehad Z Tayyeb Manal F El-Khadragy Mariam A Alkhateeb Ali O Al-Ghamdy Hus Source Type: research

Enhancement of Frozen-Thawed Human Sperm Quality with Zinc as a Cryoprotective Additive
CONCLUSIONS Zn ion is one of the antioxidants in the cell. The results of our current clinical study are sufficient to demonstrate that Zn can improve preserves sperm quality during cryopreservation when added to GEYC. The addition of 50 µM ZnSO₄ increased curve velocity, mean path velocity, sperm survival (or plasma membrane integrity), and mitochondrial membrane potential while reducing ROS production and DNA breaks compared to GEYC thawed without ZnSO₄.PMID:38698627 | DOI:10.12659/MSM.942946 (Source: Medical Science Monitor)
Source: Medical Science Monitor - May 3, 2024 Category: Research Authors: Longlong Fu Jing Ma Lixia Chen Ying Guo Wenjie Li Xingguo Zhang Wenhong Lu Shusong Wang Ying Liu Source Type: research

Therapeutic Potential of Silymarin in Mitigating Paclitaxel-Induced Hepatotoxicity and Nephrotoxicity: Insights into Oxidative Stress, Inflammation, and Apoptosis in Rats
CONCLUSION: Our findings indicate the potential of SIL to alleviate PAX-induced liver and kidney damage in rats by reducing oxidative stress, inflammation, and apoptotic processes.PMID:38700358 | DOI:10.4274/balkanmedj.galenos.2024.2024-1-60 (Source: Cancer Control)
Source: Cancer Control - May 3, 2024 Category: Cancer & Oncology Authors: Seda Yakut Tu ğçe Atcalı C üneyt Çaglayan Aykut Ulucan Fatih Mehmet Kandemir Adem Kara Turgut Anuk Source Type: research

Antioxidant network-based signatures cluster glioblastoma into distinct redox-resistant phenotypes
CONCLUSION: In summary, we provide a set of transcriptional signatures that unveil the antioxidant potential of GBM, offering a promising prognostic application and a guide for therapeutic strategies in GBM therapy.PMID:38698847 | PMC:PMC11063242 | DOI:10.3389/fimmu.2024.1342977 (Source: Cancer Control)
Source: Cancer Control - May 3, 2024 Category: Cancer & Oncology Authors: Yihan Yang Sanket More Frederik De Smet Steven De Vleeschouwer Patrizia Agostinis Source Type: research

Immuno-modulatory role of baicalin in atherosclerosis prevention and treatment: current scenario and future directions
Front Immunol. 2024 Apr 18;15:1377470. doi: 10.3389/fimmu.2024.1377470. eCollection 2024.ABSTRACTAtherosclerosis (AS) is recognized as a chronic inflammatory condition characterized by the accumulation of lipids and inflammatory cells within the damaged walls of arterial vessels. It is a significant independent risk factor for ischemic cardiovascular disease, ischemic stroke, and peripheral arterial disease. Despite the availability of current treatments such as statins, proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors, and lifestyle modifications for prevention, AS remains a leading cause of morbidity and ...
Source: Atherosclerosis - May 3, 2024 Category: Cardiology Authors: Li Wang Shenyi Huang Xiaolun Liang Junliang Zhou Yifan Han Jiangshan He Danping Xu Source Type: research

< em > Panax notoginseng < /em > Saponins Activate Nuclear Factor Erythroid 2-Related Factor 2 to Inhibit Ferroptosis and Attenuate Inflammatory Injury in Cerebral Ischemia-Reperfusion
In this study, we aimed to investigate the effects of PNS on ferroptosis and inflammation in CIRI. We induced ferroptosis in SH-SY5Y cells via erastin stimulation and oxygen glucose deprivation/re-oxygenation (OGD/R) in vitro. Furthermore, we determined the effect of PNS treatment in a rat model of middle cerebral artery occlusion/reperfusion and assessed the underlying mechanism. We also analyzed the changes in the expression of ferroptosis-related proteins and inflammatory factors in the established rat model. OGD/R led to an increase in the levels of ferroptosis markers in SH-SY5Y cells, which were reduced by PNS treatm...
Source: The American Journal of Chinese Medicine - May 3, 2024 Category: Complementary Medicine Authors: Lin-Lin Wang Man-Lin Kang Can-Wen Liu Liang Liu Biao Tang Source Type: research