Combined effects of organic and mineral UV-filters on the lugworm Arenicola marina
Chemosphere. 2024 Apr 30:142184. doi: 10.1016/j.chemosphere.2024.142184. Online ahead of print.ABSTRACTPollution from personal care products, such as UV-filters like avobenzone and nano-zinc oxide (nZnO), poses a growing threat to marine ecosystems. To better understand this hazard, especially for lesser-studied sediment-dwelling marine organisms, we investigated the physiological impacts of simultaneous exposure to nZnO and avobenzone on the lugworm Arenicola marina. Lugworms were exposed to nZnO, avobenzone, or their combination for three weeks. We assessed pollutant-induced metabolic changes by measuring key metabolic i...
Source: Chemosphere - May 2, 2024 Category: Chemistry Authors: Torben Bruhns Candela S ánchez-Girón Barba Lilian K önig Stefan Timm Kathrin Fisch Inna M Sokolova Source Type: research
Changes in life history parameters and expression of key genes of Brachionus plicatilis exposed to a combination of organic and inorganic ultraviolet filters
This study aimed to assess the comprehensive effects of organic ultraviolet filters, specifically 2-ethylhexyl-4-methoxycinnamate (EHMC), and inorganic ultraviolet filters, namely, titanium dioxide nanoparticles (TiO2 NPs), on the rotifer Brachionus plicatilis. We exposed B. plicatilis to multiple combinations of different concentrations of EHMC and TiO2 NPs to observe changes in life history parameters and the expression of genes related to reproduction and antioxidant responses. Our findings indicated that increased EHMC concentrations significantly delayed the age at first reproduction, reduced the total offspring, and ...
Source: Chemosphere - May 2, 2024 Category: Chemistry Authors: Qingqing Yu Gongyuan Wang Zhihao Shao Yunfei Sun Zhou Yang Source Type: research
Physiological and biochemical response in green mussel Perna viridis subjected to continuous chlorination: Perspective on cooling water discharge criteria
Chemosphere. 2024 Apr 30:142191. doi: 10.1016/j.chemosphere.2024.142191. Online ahead of print.ABSTRACTHeavy infestation by Perna viridis has been observed in the sub-seabed seawater intake tunnel and CWS of a tropical coastal power station in-spite of continuous low dose chlorination regime (0.2 ± 0.1 mg L-1) (CLDC), indicating periodical settlement and growth. Continuous arrival of mussels (colonized in the sub seabed tunnel intake section) at the pump house indicated that the mussels were able to tolerate and survive in a chlorinated environment, for varying time periods and were dislodged when they become weak and sub...
Source: Chemosphere - May 2, 2024 Category: Chemistry Authors: Bandita Badakumar D Inbakandan S Venkatnarayanan T V Krishna Mohan Y V Nancharaiah N K Pandey P Veeramani P Sriyutha Murthy Source Type: research
Malus toringoides (Rehd.) Hughes decoction alleviates ISO-induced cardiac fibrosis by inhibiting cardiomyocyte inflammation and pyroptosis via the HK1/NLRP3-signaling pathway
Biosci Biotechnol Biochem. 2024 May 2:zbae055. doi: 10.1093/bbb/zbae055. Online ahead of print.ABSTRACTMalus toringoides (Rehd.) Hughes leave, called "Eseye (Ese)", is a traditional medicinal plant from the Tibet province of China that has efficiency of anti-inflammatory, antioxidant and anti-apoptosis to treat cardiac conditions. We herein explored the underlying protective mechanisms of Ese decoction in isoproterenol (ISO)-induced cardiac fibrosis (CF). And treatment with an Ese decoction attenuated tissue injury and decreased the release of IL-1β, IL-18, TNF-α, and caspase-3 and elevated the Bax/Bcl-2 ratio in CF mice...
Source: Bioscience, Biotechnology, and Biochemistry - May 2, 2024 Category: Biochemistry Authors: Huiru Du Yuling Zhang Haochuan Guo Xizhen Cheng Haolin Tian Yanan Wang Hongfang Wang Yongxing Song Xuhong Duan Donglai Ma Source Type: research
Effects of micro- and nano-plastics on growth, antioxidant system, DMS, and DMSP production in Emiliania huxleyi
Environ Pollut. 2024 Apr 30:124084. doi: 10.1016/j.envpol.2024.124084. Online ahead of print.ABSTRACTDue to the potential impacts of microplastics (MPs) and nanoplastics (NPs) on algal growth and thereby affect the climate-relevant substances, dimethylsulfoniopropionate (DMSP) and dimethyl sulfide (DMS), we studied the polystyrene (PS) MPs and NPs of 1 μm and 80 nm impacts on the growth, chlorophyll content, reactive oxygen species (ROS), antioxidant enzyme activity, and DMS/DMSP production in Emiliania huxleyi. E. huxleyi is a prominent oceanic alga that plays a key role in DMS and DMSP production. The results revealed t...
Source: Environmental Pollution - May 2, 2024 Category: Environmental Health Authors: Juan Yu Ji-Yuan Tian Yu Jiang Xue-Dan Wang Xin-Ran Song Long-Fei Liu Gui-Peng Yang Source Type: research
Glyphosate presence in human sperm: First report and positive correlation with oxidative stress in an infertile French population
Ecotoxicol Environ Saf. 2024 May 1;278:116410. doi: 10.1016/j.ecoenv.2024.116410. Online ahead of print.ABSTRACTEnvironmental exposure to endocrine disruptors, such as pesticides, could contribute to a decline of human fertility. Glyphosate (GLY) is the main component of Glyphosate Based Herbicides (GBHs), which are the most commonly herbicides used in the world. Various animal model studies demonstrated its reprotoxicity. In Europe, GLY authorization in agriculture has been extended until 2034. Meanwhile the toxicity of GLY in humans is still in debate. The aims of our study were firstly to analyse the concentration of GL...
Source: Ecotoxicology and Environmental Safety - May 2, 2024 Category: Environmental Health Authors: Claudine Vasseur Lo ïse Serra Souleiman El Balkhi Ga ëlle Lefort Christelle Ram é Pascal Froment Jo ëlle Dupont Source Type: research
Cadmium promoted LPS-induced inflammation through TLR4/I κBα/NFκ-B signaling by increasing ROS-mediated incomplete autophagy
This study identified the mechanism of autophagy in Cd-aggravated immunotoxicity under infectious stress, which could arouse public attention to synergistic toxicity of Cd and bacterial or virus infection.PMID:38696874 | DOI:10.1016/j.ecoenv.2024.116405 (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - May 2, 2024 Category: Environmental Health Authors: Chuanzhi Guo Jiacheng Ruan Zehua Li Huilin Fu Kongdong Li Xun Gong Xin Gu Jie Gu Haifeng Shi Source Type: research
New Advances in the Pharmacology and Toxicology of Lithium: A Neurobiologically Oriented Overview
Pharmacol Rev. 2024 May 2;76(3):323-357. doi: 10.1124/pharmrev.120.000007.ABSTRACTOver the last six decades, lithium has been considered the gold standard treatment for the long-term management of bipolar disorder due to its efficacy in preventing both manic and depressive episodes as well as suicidal behaviors. Nevertheless, despite numerous observed effects on various cellular pathways and biologic systems, the precise mechanism through which lithium stabilizes mood remains elusive. Furthermore, there is recent support for the therapeutic potential of lithium in other brain diseases. This review offers a comprehensive ex...
Source: Pharmacological Reviews - May 2, 2024 Category: Drugs & Pharmacology Authors: Analia Bortolozzi Giovanna Fico Michael Berk Marco Solmi Michele Fornaro Joao Quevedo Carlos A Zarate Lars V Kessing Eduard Vieta Andre F Carvalho Source Type: research
Panax ginseng Ameliorates Pituitary-Ovarian Dysfunction Induced by Radiofrequency Electromagnetic Radiation from Cell Phones via Upregulation of the CREM Signaling Pathway
CONCLUSION: The findings of this study indicate that P. ginseng extract shields against pituitary-ovarian impairment linked to RF-EMR exposure from cell phones by boosting antioxidant capacity and promoting the CREM-dependent pathway.PMID:38693729 | DOI:10.2174/0115701638279386240425050818 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - May 2, 2024 Category: Drugs & Pharmacology Authors: Oyetunji A Oyewopo Olabimpe C Badejogbin Isaac O Ajadi Linus A Enye Mary B Ajadi Ikponmwosa V Ebuwa Olutunmise V Owolabi Stephanie E Areloegbe Kehinde S Olaniyi Source Type: research
Tanshinone IIA alleviates pulmonary fibrosis by modulating glutamine metabolic reprogramming based on [U- < sup > 13 < /sup > C < sub > 5 < /sub > ]-glutamine metabolic flux analysis
CONCLUSION: Tan IIA reverses glutamine metabolic reprogramming, reduces mitochondrial energy expenditure, and inhibits collagen matrix synthesis by modulating potential targets in glutamine metabolism. This novel perspective sheds light on the essential role of glutamine metabolic reprogramming in PF.PMID:38697470 | DOI:10.1016/j.jare.2024.04.029 (Source: Cell Research)
Source: Cell Research - May 2, 2024 Category: Cytology Authors: Baixi Shan Congying Guo Haoyan Zhou Jun Chen Source Type: research
Cell type-dependent modulation of senescence features using Weo electrolyzed water
This study aims to investigate whether Weo electrolyzed water (WEW) could modulate the phenotype of senescent cells. We compared normal human lung fibroblasts (BJ) and breast cancer cells (T47D) treated with hydrogen peroxide (H2O2) to induce senescence. We assessed the molecular impact of WEW on markers of cellular senescence, senescence-associated secretory phenotype (SASP) factors, and stress response genes. Treatment with WEW modulated markers of cellular senescence, such as the senescence-associated β-galactosidase (SA-β-gal) activity, EdU incorporation and p21 expression, similarly in both cell types. However, WEW ...
Source: Aging - May 2, 2024 Category: Biomedical Science Authors: Brenda L Court-Vazquez Shirley A Arroyo-Vizcarrondo Jonathan A Poli Lara Nyman Kelly Halderman Anthony Ginter Pierre-Yves Desprez Source Type: research
Combining the pharmaceutical and toxicological properties of select essential oils with their chemical components by GC-MS analysis
Chem Biodivers. 2024 May 2:e202400738. doi: 10.1002/cbdv.202400738. Online ahead of print.ABSTRACTIn the current investigation, a comprehensive analysis was carried out on essential oils (Eos) extracted from six aromatic plant species, namely Rosmarinus officinalis, Pelargonium graveolens, Thymus vulgaris, Origanum vulgare, Laurus nobilis, and Aloysia citrodora. An exploration was conducted into the chemical composition using Gas Chromatography-Mass Spectrometry (GC/MS), antioxidant properties assessed through DPPH, ABTS, CUPRAC, FRAP, MCA, and PBD assays, ecotoxicological impacts evaluated via allelopathy and the Daphnia ...
Source: Chemistry and Biodiversity - May 2, 2024 Category: Biochemistry Authors: Nilofar Nilofar Shakeel Ahmed Gokhan Zengin Simonetta Cristina Di Simone Alessandra Acquaviva Maria Loreta Libero Annalisa Chiavaroli Giustino Orlando Massimo Tacchini Maura Di Vito Luigi Menghini Claudio Ferrante Source Type: research
Cadmium promoted LPS-induced inflammation through TLR4/I κBα/NFκ-B signaling by increasing ROS-mediated incomplete autophagy
This study identified the mechanism of autophagy in Cd-aggravated immunotoxicity under infectious stress, which could arouse public attention to synergistic toxicity of Cd and bacterial or virus infection.PMID:38696874 | DOI:10.1016/j.ecoenv.2024.116405 (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - May 2, 2024 Category: Environmental Health Authors: Chuanzhi Guo Jiacheng Ruan Zehua Li Huilin Fu Kongdong Li Xun Gong Xin Gu Jie Gu Haifeng Shi Source Type: research
Glyphosate presence in human sperm: First report and positive correlation with oxidative stress in an infertile French population
Ecotoxicol Environ Saf. 2024 May 1;278:116410. doi: 10.1016/j.ecoenv.2024.116410. Online ahead of print.ABSTRACTEnvironmental exposure to endocrine disruptors, such as pesticides, could contribute to a decline of human fertility. Glyphosate (GLY) is the main component of Glyphosate Based Herbicides (GBHs), which are the most commonly herbicides used in the world. Various animal model studies demonstrated its reprotoxicity. In Europe, GLY authorization in agriculture has been extended until 2034. Meanwhile the toxicity of GLY in humans is still in debate. The aims of our study were firstly to analyse the concentration of GL...
Source: Ecotoxicology and Environmental Safety - May 2, 2024 Category: Environmental Health Authors: Claudine Vasseur Lo ïse Serra Souleiman El Balkhi Ga ëlle Lefort Christelle Ram é Pascal Froment Jo ëlle Dupont Source Type: research
Effects of micro- and nano-plastics on growth, antioxidant system, DMS, and DMSP production in Emiliania huxleyi
Environ Pollut. 2024 Apr 30:124084. doi: 10.1016/j.envpol.2024.124084. Online ahead of print.ABSTRACTDue to the potential impacts of microplastics (MPs) and nanoplastics (NPs) on algal growth and thereby affect the climate-relevant substances, dimethylsulfoniopropionate (DMSP) and dimethyl sulfide (DMS), we studied the polystyrene (PS) MPs and NPs of 1 μm and 80 nm impacts on the growth, chlorophyll content, reactive oxygen species (ROS), antioxidant enzyme activity, and DMS/DMSP production in Emiliania huxleyi. E. huxleyi is a prominent oceanic alga that plays a key role in DMS and DMSP production. The results revealed t...
Source: Environmental Pollution - May 2, 2024 Category: Environmental Health Authors: Juan Yu Ji-Yuan Tian Yu Jiang Xue-Dan Wang Xin-Ran Song Long-Fei Liu Gui-Peng Yang Source Type: research
