Oxidative and Antioxidant Indices to HIIT and Aloe Vera Supplementation in Patients With T2DM
Conditions: Diabetes Type 2 Interventions: Behavioral: Exercise; Dietary Supplement: Aloe vera Sponsors: University of Nis Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 22, 2024 Category: Research Source Type: clinical trials

Single-Blind Study Assessing the Use of a Topical Antioxidant With A Series of Laser Procedures to Reduce Sebum Production
Conditions: Acne Interventions: Drug: Topical Antioxidant Serum; Device: AviClear Laser Sponsors: Austin Institute for Clinical Research; SkinCeuticals Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 19, 2024 Category: Research Source Type: clinical trials

The effect of selenium supplementation on oxidative stress, clinical symptoms and mental health status in patients with migraine: a study protocol for a double-blinded randomized clinical trial
DiscussionOxidative stress is recognized as a key contributor to migraine pathogenesis. Selenium is an essential trace element with antioxidant properties, capable of crossing the blood –brain barrier (BBB), holding promise to alleviate the oxidative stress and neurotoxicity. Thus, selenium may beneficially affect clinical symptoms and oxidative stress as well as the quality of life in migraine patients.Trial registrationThis trial was registered in the Iranian Registry of Clinical Trials (https://www.irct.ir/) on 27 May 2023 with the code number IRCT20121216011763N60. (Source: Trials)
Source: Trials - March 22, 2024 Category: Research Source Type: clinical trials

The effects of intermittent fasting diet on quality of life, clinical symptoms, inflammation, and oxidative stress in overweight and obese postmenopausal women with rheumatoid arthritis: study protocol of a randomized controlled trial
DiscussionStudies show fasting has beneficial effects on inflammatory markers and results in an improvement in the health of different populations. Literature review shows it seems there is no study in this field to evaluate the effects of IF on RA patients, and they are limited to other types of fasting. However, studies show IF can have many positive effects on chronic and autoimmune diseases. Therefore, IF may have positive effects on these patients.Trial registrationIRCT20230217057441N1. Registered on 14 February 2023.https://en.irct.ir/user/trial/68669. (Source: Trials)
Source: Trials - March 5, 2024 Category: Research Source Type: clinical trials

Coenzyme Q10 supplementation in burn patients: a double-blind placebo-controlled randomized clinical trial
ConclusionResults showed that in patients with burn injury, CoQ10 administration had no effect on inflammatory markers and oxidative stress, although serum albumin levels were improved after supplementation. Further studies with albumin as the primary outcome are needed to confirm this finding. (Source: Trials)
Source: Trials - March 2, 2024 Category: Research Source Type: clinical trials

Effect of Carob Molasse Pose Flour and Germ On Glycemic Response and Antioxidant Capacity
Conditions: Healthy Participants Interventions: Combination Product: Germ and Carob Molasses Pulp added standard whole wheat breads Sponsors: Toros University Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 10, 2024 Category: Research Source Type: clinical trials

Effect of Topical Agents With Various Antioxidant Containts on Photodamage Skin Induced
Conditions: Photodamaged Skin Interventions: Combination Product: Antioxidants; Combination Product: Vehicle Sponsors: Universitas Padjadjaran Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 14, 2023 Category: Research Source Type: clinical trials

Effects of Antiplatelet and Antioxidant Agents on Drusen Progression: A Pilot, Prospective Cohort Study
Conditions: Dry Age-related Macular Degeneration Interventions: Drug: Aspirin, Clopidogrel, N-acetylcysteine Sponsors: Navamindradhiraj University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 11, 2023 Category: Research Source Type: clinical trials

Assessment of Antioxidant Therapy on Oxidative Stress Biomarkers in Type 2 Diabetic Patients With Neuropathy
Conditions: Peripheral Diabetic Neuropathy Interventions: Drug: Resveratrol, Alpha lipoic acid, Super oxide dismutase; Drug: Resveratrol; Drug: Alpha lipoic acid; Drug: Super Oxide Dismutase Sponsors: Khyber Medical University Peshawar Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 14, 2023 Category: Research Source Type: clinical trials

Effect of inulin supplementation on clinical symptoms, inflammatory and oxidative stress markers in women with migraine: study protocol for a randomized clinical trial
DiscussionThis clinical trial aims to evaluate the effect of inulin supplementation on inflammatory status, oxidative stress, intestinal permeability, clinical symptoms, mental health, and QOL in women with migraine. The findings of this trial could contribute to the identification of mechanistic action and evidence-based clinical guidelines that address gut microbiota manipulation to maximize health benefits in the management of clinical outcomes in migraine patients.Trial registrationIranian Registry of Clinical Trials (www.irct.ir) (ID: IRCT20121216011763N58). Registration date: 23 April 2023.Trial statusThe protocol is...
Source: Trials - November 11, 2023 Category: Research Source Type: clinical trials

The effects of intermittent fasting diet alone or in combination with probiotic supplementation in comparison with calorie-restricted diet on metabolic and hormonal profile in patients with polycystic ovary syndrome: study protocol for a randomized clinical trial
DiscussionWe hypothesized that 10-h TRE administered alone or in combination with probiotic supplementation to overweight and obese PCOS subjects would lead to weight loss and improved metabolic, hormonal, inflammatory, and antioxidant markers compared to control subjects following a standard 3-meal-per-day CR diet.Ethical aspectsThe current trial received approval from the Medical Ethics Committee of Tehran University of Medical Sciences, Tehran, Iran (IR.TUMS.MEDICNE.REC.1401.425).Trial registrationIranian Registry of Clinical Trials IRCT20121110011421N5. Registered on 3 October 2022. (Source: Trials)
Source: Trials - October 25, 2023 Category: Research Source Type: clinical trials

the Ameliorating Effects of Antioxidant Gel on Female Arousal Disorder and Sexual Dysfunction
Conditions: Female Sexual Dysfunction Interventions: Drug: Kaempferol Sponsors: Deraya University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 29, 2023 Category: Research Source Type: clinical trials

Level of DNA-fragmentation Before and After Antioxidant-based Therapies in Male Infertility
Condition:   Infertility, Male Intervention:   Dietary Supplement: Intake of antioxidant supplement Sponsor:   Janna Pape Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 22, 2023 Category: Research Source Type: clinical trials