Evaluation of Melatonin and its Nanostructures Effects on Skin Disorders Focused on Wound Healing
Mini Rev Med Chem. 2024 Apr 29. doi: 10.2174/0113895575299255240422055203. Online ahead of print.ABSTRACTSkin is the largest organ of the human body functioning as a great primitive defensive barrier against different harmful environmental factors. However, it is damaged through varying injuries such as different wounds, burns, and skin cancers that cause disruption in internal organs and essential mechanisms of the body through inflammation, oxidation, coagulation problems, infection, etc. Melatonin is the major hormone of the pineal gland that is also effective in skin disorders due to strong antioxidant and anti-inflamm...
Source: Mini Reviews in Medicinal Chemistry - April 30, 2024 Category: Chemistry Authors: Seyedeh Mohaddeseh Mousavi Leila Etemad Davood Yari Maryam Hashemi Zahra Salmasi Source Type: research
Effects of priming glycosyltransferase genes cps 2E and cps 4E on the exopolysaccharide biosynthesis by Lactiplantibacillus plantarum YM-4-3 strain
In conclusion, this study contributes to the efficient production and application of L. plantarum EPS and helps to understand the mechanism of EPS regulation in L. plantarum.PMID:38685537 | DOI:10.1016/j.ijbiomac.2024.131813 (Source: International Journal of Biological Macromolecules)
Source: International Journal of Biological Macromolecules - April 30, 2024 Category: Biochemistry Authors: Tian Wang Yong-Gang Xiong Tian-Zhao Si Jin-Ping Yan Xiao-Ran Li Chen-Jian Liu En Yang Source Type: research
Assessing the influence of micelle silymarin on laying hens' performance, egg quality, water loss and blood profile
AbstractMicelle silymarin (MS) is known for its various beneficial properties, including antiswelling, antioxidant, hepatoprotective and antidiabetic effects. The primary goal of this research was to investigate how MS impacts the performance, egg quality, water loss and blood profile of laying hens. 288 Hy-Line brown laying hens, 28 weeks in age, were utilized for this experiment. The hens were randomly allocated into three dietary treatment groups, with each group comprising eight replicates of 12 hens, each housed in individual pens with access to feed and water. Over a 12-week feeding trial, the hens were provided with...
Source: Journal of Animal Physiology and Animal Nutrition - April 30, 2024 Category: Zoology Authors: Golam S. Ahammad,
Yong H. Jeon,
In H. Kim Tags: ORIGINAL ARTICLE Source Type: research
Curcumin attenuates brain aging by reducing apoptosis and oxidative stress
AbstractBrain aging is a physiological event, and oxidative stress and apoptosis are involved in the natural aging process of the brain. Curcumin is a natural antioxidant with potent anti-aging and neuroprotective properties. Therefore, we investigated the protective effects of curcumin on brain apoptosis and oxidative stress, brain-derived neurotrophic factor (BDNF), and vascular endothelial growth factor (VEGF) in aged rats. Old female Wistar rats were randomly divided into three groups (n = 7); as follows: (1) control; (2); saline and (3) curcumin (received 30 mg/kg of curcumin, 5 days/week for 8 weeks, intraperit...
Source: Metabolic Brain Disease - April 30, 2024 Category: Neurology Source Type: research
Zhilong Huoxue Tongyu capsule improves myocardial ischemia/reperfusion injury via the PI3K/AKT/Nrf2 axis
ConclusionsZL protects against MI/RI-induced ferroptosis by modulating the PI3K/AKT signaling pathway, leading to increased Nrf2 expression and activation of the HO-1/GPX4 pathway. These findings shed light on the potential therapeutic mechanisms of ZL in the context of cardiovascular diseases. (Source: PLoS One)
Source: PLoS One - April 30, 2024 Category: Biomedical Science Authors: Xiaoping Zhao Source Type: research
Cancers, Vol. 16, Pages 1750: Anticancer Activity of Encapsulated Pearl Millet Polyphenol-Rich Extract against Proliferating and Non-Proliferating Breast Cancer Cells In Vitro
Ammari
Maciej Wnuk
Plant-derived polyphenols are bioactive compounds with potential health-promoting properties including antioxidant, anti-inflammatory, and anticancer activity. However, their beneficial effects and biomedical applications may be limited due to their low bioavailability. In the present study, we have considered a microencapsulation-based drug delivery system to investigate the anticancer effects of polyphenol-rich (apigenin, caffeic acid, and luteolin) fractions, extracted from a cereal crop pearl millet (Pennisetum glaucum), using three phenotypically different cellular models of breast cancer in v...
Source: Cancers - April 30, 2024 Category: Cancer & Oncology Authors: Latifa Hajri Anna Lewi ńska Iwona Rzeszutek Bernadetta Oklejewicz Renata Wojnarowska-Nowak Agnieszka Krogul-Sobczak Ewa Szpyrka Alfredo Aires Soumaya Ghodbane Mohamed Ammari Maciej Wnuk Tags: Article Source Type: research
Molecules, Vol. 29, Pages 2067: Green and Efficient Extraction of Phenolic Components from Plants with Supramolecular Solvents: Experimental and Theoretical Studies
Li-Mei Lin
The supramolecular solvent (SUPRAS) has garnered significant attention as an innovative, efficient, and environmentally friendly solvent for the effective extraction and separation of bioactive compounds from natural resources. However, research on the use of a SUPRAS for the extraction of phenolic compounds from plants, which are highly valued in food products due to their exceptional antioxidant properties, remains scarce. The present study developed a green, ultra-sound-assisted SUPRAS method for the simultaneous determination of three phenolic acids in Prunella vulgaris using high-performance liquid c...
Source: Molecules - April 30, 2024 Category: Chemistry Authors: Bo-Hou Xia Zhi-Lu Yu Yu-Ai Lu Shi-Jun Liu Ya-Mei Li Ming-Xia Xie Li-Mei Lin Tags: Article Source Type: research
Molecules, Vol. 29, Pages 2066: Study on the Skincare Effects of Red Rice Fermented by Aspergillus oryzae In Vitro
This study utilized red rice as a substrate for fermentation by Aspergillus oryzae, producing a substance known as red rice Aspergillus oryzae fermentation (RRFA). We conducted a preliminary analysis of RRFA’s composition followed by an evaluation of its skincare potential through various in vitro tests. Our objective was to develop a safe and highly effective skincare component for potential cosmetic applications. RRFA’s constituents were assessed using high-performance liquid chromatography (HPLC), Kjeldahl nitrogen determination, the phenol-sulfuric acid method, and enzyme-linked immunosorben...
Source: Molecules - April 30, 2024 Category: Chemistry Authors: Mo Chen Yi Sun Le Zhu Lingyu Li Ya Zhao Tags: Article Source Type: research
The role of edible mushrooms in the Brazilian diet: a comprehensive analysis
This study aims to examine the role of edible mushrooms in the Brazilian diet, considering their strategic significance in meeting nutritional goals within sustainable development. Despite their potential in the nutrition of the Brazilian population, significant knowledge gaps still exist. To address this, the authors formulated this study into five main sections: the consumption of edible mushrooms in Brazil, the factors influencing the consumption, the occurrence of edible mushrooms in Brazil, the nutritional contribution of mushrooms consumed in Brazil and sustainable mushroom production in Brazil.The authors compiled c...
Source: Nutrition and Food Science - April 29, 2024 Category: Nutrition Authors: Ana J úlia Souto Carvalho Jhonatan Rafael Z árate-Salazar Michelle Cristine Medeiros Jacob Patr ícia Lima Araújo S ávio Marcelino Gomes Fillipe De Oliveira Pereira Source Type: research
Synthesis, Crystal structure, Lipophilicity, Antioxidant, Binding interaction and Antibacterial investigation against Methicillin-Resistant Staphylococcus aureus of Ni(II) Schiff base complex: Combined Theoretical and Experimental Approaches
New J. Chem., 2024, Accepted Manuscript DOI: 10.1039/D3NJ05150A, PaperBidhan Chandra Samanta, Arpita Das, Ribhu Maity, Tuhin Sarkar, Priyanka Das, Paula Brand ão, Tithi Maity, Keka Sarkar Herein, we report the synthesis, crystal structure and antibacterial activity of a new Ni(II) complex derived from N, O donor (E)-2,4-dibromo-6-(2-(1-phenylethylimino) ethyl) phenol ligand. Both the ligand and the complex... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - New J. Chem. latest articles)
Source: RSC - New J. Chem. latest articles - April 29, 2024 Category: Chemistry Authors: Bidhan Chandra Samanta Source Type: research
From Antioxidant to Anticancer is Vitamin C Effective in Colorectal Cancer?
Asian Pac J Cancer Prev. 2024 Apr 1;25(4):1107-1108. doi: 10.31557/APJCP.2024.25.4.1107.NO ABSTRACTPMID:38679968 | DOI:10.31557/APJCP.2024.25.4.1107 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 29, 2024 Category: Cancer & Oncology Authors: Kanza Farhan Muhammad Burhan Tariq Ahmed Saddiq Mansha Mansoor Aliza Ahmed Abdul-Samed Mohammed Source Type: research
Pharmacotherapeutic Potential of Bitter Gourd ( < em > Momordica charantia < /em > ) in Age-related Neurological Diseases
J Integr Neurosci. 2024 Apr 23;23(4):86. doi: 10.31083/j.jin2304086.ABSTRACTDue to the growth of the elderly population, age-related neurological disorders are an increasing problem. Aging begins very gradually and later leads to several neurological issues such as lower neurotransmitter levels, oxidative stress, neuronal inflammation, and continual neuronal loss. These changes might contribute to brain disorders such as Alzheimer's disease (AD), dementia or mild cognitive impairment, and epilepsy and glioma, and can also aggravate these disorders if they were previously present. Momordica charantia (bitter gourd), a membe...
Source: Journal of Integrative Neuroscience - April 29, 2024 Category: Neuroscience Authors: Seyed Mohammad Hosein Hosseini Adarmanabadi Orod Jalali Khalil Abadi Amirhossein Amiri Rozhina Tamannaeifar Sahar Balanian Mehdi Rasekhjam Mohammad Sadra Samiazar Sara Hasanpour Samira Peiravi Dorsa Alijanzadeh Mohadeseh Poudineh Hamidreza Amiri Seyed Ami Source Type: research
Antioxidant and anti ‑inflammatory effects of esculin and esculetin (Review)
Exp Ther Med. 2024 Apr 12;27(6):248. doi: 10.3892/etm.2024.12536. eCollection 2024 Jun.ABSTRACTFraxinus chinensis Roxb is a deciduous tree, which is distributed worldwide and has important medicinal value. In Asia, the bark of Fraxinus chinensis Roxb is a commonly used traditional Chinese medicine called Qinpi. Esculetin is a coumarin compound derived from the bark of Fraxinus chinensis Roxb and its glycoside form is called esculin. The aim of the present study was to systematically review relevant literature on the antioxidant and anti-inflammatory effects of esculetin and esculin. Esculetin and esculin can promote the ex...
Source: Experimental and Therapeutic Medicine - April 29, 2024 Category: General Medicine Authors: Shaohua Ju Youli Tan Qiang Wang Ling Zhou Kun Wang Chenghong Wen Mingjian Wang Source Type: research
From Antioxidant to Anticancer is Vitamin C Effective in Colorectal Cancer?
Asian Pac J Cancer Prev. 2024 Apr 1;25(4):1107-1108. doi: 10.31557/APJCP.2024.25.4.1107.NO ABSTRACTPMID:38679968 | DOI:10.31557/APJCP.2024.25.4.1107 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 29, 2024 Category: Cancer & Oncology Authors: Kanza Farhan Muhammad Burhan Tariq Ahmed Saddiq Mansha Mansoor Aliza Ahmed Abdul-Samed Mohammed Source Type: research
