Structural characterization, antioxidant, and anti-inflammatory activity of polysaccharides from Plumula Nelumbinis
Int J Biol Macromol. 2022 May 17:S0141-8130(22)01067-4. doi: 10.1016/j.ijbiomac.2022.05.097. Online ahead of print.ABSTRACTA polysaccharide from Plumula Nelumbinis (PNP), was isolated and purified. PNP had a molecular weight of 450 kDa and consisted five monosaccharides, including rhamnose, galacturonic acid, xylose, galactose, and arabinose. The methylation and nuclear magnetic resonance (NMR) analysis revealed that the main glycosidic linkage types of PNP were →5)-α-L-Araf-(1→, →3)-β-D-Galp-(1→, β-D-Xylp-(→1, →3,4)-β-D-Rhap-(1→, →4)-β-D-GalpA-(1→. In the range of 25-1200 μg/mL, PNP had no cytotoxi...
Source: International Journal of Biological Macromolecules - May 20, 2022 Category: Biochemistry Authors: Qingsong Zheng Juncheng Chen Yi Yuan Xia Zhang Lin Li Yongzhen Zhai Xiao Gong Bing Li Source Type: research

Structural characterization and biological evaluation of a new O-acetyl-1,4-linked- β-d-mannan possessed potential application in hydrophilic polymer materials from Dendrobium devonianum
Int J Biol Macromol. 2022 May 17:S0141-8130(22)01072-8. doi: 10.1016/j.ijbiomac.2022.05.098. Online ahead of print.ABSTRACTTo explore the active polysaccharides from Dendrobium devonianum, a novel O-acetylmannan (DDP-1) with molecular weight of 117 kDa was isolated from D. devonianum. The chemical and instrumental analysis indicated that the DDP-1 was a homopolysaccharide containing a backbone chain composed of →4)-β-d-Manp-(1 → (71.4%) residue with internal →4)-2-O-acetyl-β-d-Manp-(1 → (14.2%), →4)-3-O-acetyl-β-d-Manp-(1 → (7.1%), and non-reducing end β-d-Manp-(1 → (7.3%) residues. Anticancer assay in vi...
Source: International Journal of Biological Macromolecules - May 20, 2022 Category: Biochemistry Authors: Tao-Bin He Yan-Ping Huang Xuan-Jun Wang Jun Sheng Jiang-Miao Hu Source Type: research

Structural characterization of a homopolysaccharide produced by Weissella cibaria FMy 2-21-1 and its potential application as a green corrosion inhibiting film
Int J Biol Macromol. 2022 May 17:S0141-8130(22)01079-0. doi: 10.1016/j.ijbiomac.2022.05.105. Online ahead of print.ABSTRACTSteel corrosion is a global issue that affects safety and the economy. Currently, the homopolysaccharide (HoPS) structure of a novel lactic acid bacterium (LAB) is under study, as well as its application as a green corrosion inhibitor. Weissella cibaria FMy 2-21-1 is a LAB strain capable of producing HoPS in sucrose enriched media. The isolated and purified HoPS was characterized by different spectroscopic analyses as a linear α-1,6 dextran adopting a random coil conformation, with high molecular weig...
Source: International Journal of Biological Macromolecules - May 20, 2022 Category: Biochemistry Authors: Ren é Emanuel Lobo Patricio Andr és Orrillo Susana Beatriz Ribotta Graciela Font de Valdez Mercedes Santos Garc ía Jos é Carlos Rodríguez Cabello Mar ía Inés Torino Source Type: research

Thermal, flammability, and antimicrobial properties of arrowroot (Maranta arundinacea) fiber reinforced arrowroot starch biopolymer composites for food packaging applications
Int J Biol Macromol. 2022 May 17:S0141-8130(22)01078-9. doi: 10.1016/j.ijbiomac.2022.05.104. Online ahead of print.ABSTRACTUsing the solution casting method, a novel biodegradable thermoplastic arrowroot (Maranta arundinacea) starch (TPAS) films containing arrowroot fiber (AF) at different concentrations (0, 2, 4, 6, 8, and 10 wt%) were developed and characterized in terms of thermal, antibacterial activity, water vapor permeability (WVP), biodegradability, and light transmittance properties. The TPAS/AF-10 biocomposite film revealed a higher degradation temperature (313.02 °C) than other biocomposite films, indicating be...
Source: International Journal of Biological Macromolecules - May 20, 2022 Category: Biochemistry Authors: J Tarique S M Sapuan A Khalina R A Ilyas E S Zainudin Source Type: research

Design of asymmetric-adhesion lignin-reinforced hydrogels based on disulfide bond crosslinking for strain sensing application
Int J Biol Macromol. 2022 May 17:S0141-8130(22)01075-3. doi: 10.1016/j.ijbiomac.2022.05.101. Online ahead of print.ABSTRACTSoft and elastic polymer hydrogel materials are booming in the fields of wearable biomimetic skin, sensors, robotics, and bioelectrodes. Currently, many researchers are exploring new chemistries for the preparation of hydrogels to improve their performance. In the present study, we design and develop a strategy to prepare lignin reinforced hydrogels based on disulfide bond crosslinking mechanisms, and resultant hydrogels exhibit excellent stretchability, with tensile strain of up to 1085.4%, and high a...
Source: International Journal of Biological Macromolecules - May 20, 2022 Category: Biochemistry Authors: Chenglong Fu Yonghao Ni Lihui Chen Fang Huang Qingxian Miao Liulian Huang Source Type: research

Chitosan-based composite film adsorbents reinforced with nanocellulose for removal of Cu(II) ion from wastewater: Preparation, characterization, and adsorption mechanism
In this study, the adsorption film was prepared with excellent mechanical properties and adsorption properties by blending chitosan (CS), poly (vinyl pyrrolidone) (PVP), β-cyclodextrin (β-CD), and nanocellulose (NCC). Fourier transform infrared spectroscopy, X-ray diffraction analysis, and scanning electron microscopy were used to investigate the microstructure of the film. The effects of the NCC content, contact time, temperature, initial concentration, and pH on the adsorption of Cu(II) ion were investigated. X-ray photoelectron spectroscopy (XPS) was used to explore the adsorption mechanism. The results showed that a ...
Source: International Journal of Biological Macromolecules - May 20, 2022 Category: Biochemistry Authors: HuiQiang Zeng HongYing Hao Xuhong Wang Ziqiang Shao Source Type: research

Particle-dependent reproduction and exogenic biopolymer secretion of protozoa co-cultured rotifers
Int J Biol Macromol. 2022 May 16:S0141-8130(22)00975-8. doi: 10.1016/j.ijbiomac.2022.05.020. Online ahead of print.ABSTRACTThe rotifer-specific exogenic biopolymer, named Rotimer and its related molecular processes are affected by physical and chemical factors (e.g., temperature, pH or metal ions); however, the study of biological influences (e.g., the presence protozoa) concerning the particle-dependent reproduction (egg laying) and 'biopolymer producing capacity' (BPC) of rotifers is the objective of the present work. Non-planktonic rotifer species (Philodina acuticornis, Adineta vaga, Euchlanis dilatata, and Lecane bull...
Source: International Journal of Biological Macromolecules - May 19, 2022 Category: Biochemistry Authors: Zsolt Datki Rita Sinka Bence Galik Zita Galik-Olah Source Type: research

Upregulation of biochemical and biophysical properties of cell-laden microfiber, silk-hyaluronic acid composite
We present a binary hybrid silk and hyaluronic acid hydrogel microfiber generated through a microfluidic system to encapsulate cells with superior mechanical properties and biocompatibility. Cell-laden hydrogel microfibers were continuously produced through coaxial double orifice microfluidic device and horseradish peroxidase mediated crosslinking, which conjugated introduce phenolic moieties in the backbone of silk fibroin and HA derivatives (Silk-Ph and HA-Ph, respectively). The iterative hybrid Silk-Ph + HA-Ph fibers were fabricated in tunable size distribution between 195 and 680 μm through control of outer flow veloc...
Source: International Journal of Biological Macromolecules - May 19, 2022 Category: Biochemistry Authors: Seyed Ali Fatahian Alireza Motavalizadehkakhky Malihesadat Hosseiny Seyed Mohammad Mahdi Nouri Rahele Zhiani Mojtaba Sohrabpour Mehdi Khanmohammadi Source Type: research

A review on plant polysaccharide based on drug delivery system for construction and application, with emphasis on traditional Chinese medicine polysaccharide
Int J Biol Macromol. 2022 May 16:S0141-8130(22)01057-1. doi: 10.1016/j.ijbiomac.2022.05.087. Online ahead of print.ABSTRACTCarbohydrate polymers with unique chemical composition, molecular weight and functional chemical groups show multiple potentials in drug delivery. Most carbohydrate polymers such as plant polysaccharides exhibit advantages of biodegradability, ease of modification, low immunogenicity and low toxicity. They can be conjugated, cross-linked or functionally modified, and then used as nanocarrier materials. Polysaccharide drug delivery system can avoid the phagocytosis of the reticuloendothelial system, pre...
Source: International Journal of Biological Macromolecules - May 19, 2022 Category: Biochemistry Authors: Hexin Gong Weinan Li Jialin Sun Li Jia Qingxia Guan Yuyan Guo Yanhong Wang Source Type: research

Alginate/gelatin-based hybrid hydrogels with function of injecting and encapsulating cells in situ
Int J Biol Macromol. 2022 May 16:S0141-8130(22)01028-5. doi: 10.1016/j.ijbiomac.2022.05.058. Online ahead of print.ABSTRACTMulti-network hydrogels with high strength and toughness have attracted increasing attention. Herein, a hybrid hydrogel consisting of alginate, gelatin, and polyacrylamide was constructed with the combination of advantages of natural and synthetic polymers. Alginate grafted with host-guest complex of βCD/Ad-AAm was first prepared, namely Alg-βCD/Ad-AAm, then further crosslink with gelatin methacryloyl (GelMA) to form hydrogel via one-step UV light initiation. The hydrogel produced by this method has ...
Source: International Journal of Biological Macromolecules - May 19, 2022 Category: Biochemistry Authors: Pengfei Ren Dandan Wei Min Liang Li Xu Tianzhu Zhang Qianli Zhang Source Type: research

Chitosan-CaP microflowers and metronidazole loaded calcium alginate sponges with enhanced antibacterial, hemostatic and osteogenic properties for the prevention of dry socket after tooth removal
Int J Biol Macromol. 2022 May 16:S0141-8130(22)01064-9. doi: 10.1016/j.ijbiomac.2022.05.094. Online ahead of print.ABSTRACTTooth removal, particularly for patients with severe periodontitis, can frequently cause massive bleeding, postoperative infection, and bone resorption, resulting in a dry socket. Thus, developing bio-multifunctional materials with excellent antibacterial, hemostatic, and osteogenic characteristics for the prevention of dry sockets after tooth removal is highly desirable in clinical applications. Herein, chitosan-CaP microflowers (CM) and metronidazole (MD) loaded calcium alginate (CA) sponges (CA@CM/M...
Source: International Journal of Biological Macromolecules - May 19, 2022 Category: Biochemistry Authors: Mingzhe Yan Yingxiao Pan Shulai Lu Xin Li Danyang Wang Tianyi Shao Zhihang Wu Qihui Zhou Source Type: research

Purification, structural characterization and immunomodulatory activities of a polysaccharide from the fruiting body of Morchella sextelata
Int J Biol Macromol. 2022 May 16:S0141-8130(22)01066-2. doi: 10.1016/j.ijbiomac.2022.05.096. Online ahead of print.ABSTRACTA novel polysaccharide (MSP-1) was isolated from the fruiting body of Morchella sextelata and purified using DEAE-52 and Sephadex G-75. The molecular weight of MSP-1 was 1.17 × 104 Da, as detected by HPLC analysis. The monosaccharide composition of MSP-1 was mannose and glucose at a ratio of 1.00: 1.25. Methylation and NMR results revealed that the backbone of MSP-1 was composed of →4)-β-D-Manp-(1→, →4)-β-D-Glcp-(1→, →4)-α-D-Glcp-(1→, and →4, 6)-α-D-Glcp-(1→. SEM images of MSP-1 pr...
Source: International Journal of Biological Macromolecules - May 19, 2022 Category: Biochemistry Authors: Meng-Ting Kuang Jing-Yue Xu Jin-Yu Li Liu Yang Bo Hou Qi Zhao Jiang-Miao Hu Source Type: research

Sulfated carboxymethylcellulose-based scaffold mediated delivery of Timp3 alleviates osteoarthritis
Int J Biol Macromol. 2022 May 16:S0141-8130(22)01063-7. doi: 10.1016/j.ijbiomac.2022.05.093. Online ahead of print.ABSTRACTOsteoarthritis (OA) is a debilitating progressive joint disease with high incidence and socioeconomic burden. However, no disease-modifying treatment is currently available for OA. Here, we report a sulfated carboxymethylcellulose-based scaffold mediated delivery of tissue inhibitor of metalloprotease 3 (Timp3) as a disease-modifying therapeutic strategy for OA. First, we chemically modified carboxymethylcellulose (CMC) to sulfated carboxymethylcellulose (sCMC) to impart native-like electrostatic inter...
Source: International Journal of Biological Macromolecules - May 19, 2022 Category: Biochemistry Authors: Arijit Bhattacharjee Dhirendra S Katti Source Type: research

Particle-dependent reproduction and exogenic biopolymer secretion of protozoa co-cultured rotifers
Int J Biol Macromol. 2022 May 16:S0141-8130(22)00975-8. doi: 10.1016/j.ijbiomac.2022.05.020. Online ahead of print.ABSTRACTThe rotifer-specific exogenic biopolymer, named Rotimer and its related molecular processes are affected by physical and chemical factors (e.g., temperature, pH or metal ions); however, the study of biological influences (e.g., the presence protozoa) concerning the particle-dependent reproduction (egg laying) and 'biopolymer producing capacity' (BPC) of rotifers is the objective of the present work. Non-planktonic rotifer species (Philodina acuticornis, Adineta vaga, Euchlanis dilatata, and Lecane bull...
Source: International Journal of Biological Macromolecules - May 19, 2022 Category: Biochemistry Authors: Zsolt Datki Rita Sinka Bence Galik Zita Galik-Olah Source Type: research

Upregulation of biochemical and biophysical properties of cell-laden microfiber, silk-hyaluronic acid composite
We present a binary hybrid silk and hyaluronic acid hydrogel microfiber generated through a microfluidic system to encapsulate cells with superior mechanical properties and biocompatibility. Cell-laden hydrogel microfibers were continuously produced through coaxial double orifice microfluidic device and horseradish peroxidase mediated crosslinking, which conjugated introduce phenolic moieties in the backbone of silk fibroin and HA derivatives (Silk-Ph and HA-Ph, respectively). The iterative hybrid Silk-Ph + HA-Ph fibers were fabricated in tunable size distribution between 195 and 680 μm through control of outer flow veloc...
Source: International Journal of Biological Macromolecules - May 19, 2022 Category: Biochemistry Authors: Seyed Ali Fatahian Alireza Motavalizadehkakhky Malihesadat Hosseiny Seyed Mohammad Mahdi Nouri Rahele Zhiani Mojtaba Sohrabpour Mehdi Khanmohammadi Source Type: research