Stretchable, antifatigue, and intelligent nanocellulose hydrogel colorimetric film for real-time visual detection of beef freshness
In this study, a nanocellulose hydrogel colorimetric film with enhanced stretchability, antifatigue properties, and color stability was prepared using soy hull nanocellulose (SHNC), polyvinyl alcohol (PVA), sodium alginate (SA), and anthocyanin (Anth) as raw materials. This hydrogel colorimetric film was used to detect beef freshness. The structure and properties (e.g., mechanical, thermal stability and hydrophobicity) of these hydrogel colorimetric films were characterized using different techniques. Fourier-transform infrared spectroscopy revealed the presence of hydrogen and ester bonds in the hydrogel colorimetric film...
Source: International Journal of Biological Macromolecules - April 16, 2024 Category: Biochemistry Authors: Kejin Yu Lina Yang Siyu Zhang Ning Zhang Mengxi Xie Miao Yu Source Type: research

Preparation of pH-sensitive porous polylactic acid-based medical dressing with self-pumping function
In this study, we fabricated a pH-sensitive colorimetric chronic wound dressing with self-pumping function using electrostatic spinning technology. It consisted of three layers: a polylactic acid-curcumin (PCPLLA) hydrophobic layer, a hydrolyzed polyacrylonitrile (HPAN) transfer layer, and a polyacrylonitrile-purple kale anthocyanin (PAN-PCA) hydrophilic layer. The results showed that the preparation of porous PLLA fiber membrane loaded with 0.2 % Cur was achieved by adjusting the spinning-related parameters, which could ensure that the composite dressing had sufficient anti-inflammatory, antibacterial and antioxidant prop...
Source: International Journal of Biological Macromolecules - April 16, 2024 Category: Biochemistry Authors: Zijian Zhang Jianyong Li Yi Wang Xiaojie Wang Liming Wang Yinghua Qiu Fangyi Li Jianfeng Li Maocheng Ji Jia Man Source Type: research

Polyvinyl alcohol/chitosan quaternary ammonium salt composite hydrogel with directional macroporous structure for photothermal synergistic antibacterial and wound healing promotion
Int J Biol Macromol. 2024 Apr 14:131549. doi: 10.1016/j.ijbiomac.2024.131549. Online ahead of print.ABSTRACTAfter skin tissue trauma, wound infections caused by bacteria posed a great threat to skin repair. However, resistance to antibiotics, the current treatment of choice for bacterial infections, greatly affected the efficiency of anti-infection and wound healing. Therefore, there has been a critical need for the development of novel antimicrobial materials and advanced therapeutic methods to aid in skin repair. In this paper, rGO-PDA@ZIF-8 nanofillers were prepared by coating graphene oxide (GO) with dopamine (DA), fol...
Source: International Journal of Biological Macromolecules - April 16, 2024 Category: Biochemistry Authors: Xianyu Lan Hang Yang Yuzhu Xiong Guanyue Zeng Fuping Dong Source Type: research

The effect of EGCG/tyrosol-loaded chitosan/lecithin nanoparticles on hyperglycemia and hepatic function in streptozotocin-induced diabetic mice
In conclusion, the EGCG/tyrosol-loaded C/L NPs reduced hyperglycemia, oxidative stress, and inflammation in diabetic mice. These findings suggest that EGCG/tyrosol-loaded C/L NPs could be a promising therapeutic option for type 2 diabetes management.PMID:38626839 | DOI:10.1016/j.ijbiomac.2024.131496 (Source: International Journal of Biological Macromolecules)
Source: International Journal of Biological Macromolecules - April 16, 2024 Category: Biochemistry Authors: Ali Es-Haghi Mozhgan Soltani Masoud Homayouni Tabrizi Maryam Karimi Noghondar Nilofar Khatamian Niloofar Barati Naeeni Matin Kharaghani Source Type: research

Characterization of emulgels formulated with phycocyanin and diutan gum as a novel approach for biocompatible delivery systems
Int J Biol Macromol. 2024 Apr 14:131599. doi: 10.1016/j.ijbiomac.2024.131599. Online ahead of print.ABSTRACTPhycocyanin (PC), a protein derived from algae, is non-toxic and biocompatible. Due to its environmental and sustainable properties, it has been studied as an alternative stabilizer for food emulsions. In this sense, the main objective of this work is to evaluate the effectiveness of PC and its use in combination with diutan gum (DG), a biological macromolecule, to prepare emulgels formulated with avocado oil. Z-potential measurements show that the optimum pH for working with PC is 2.5. Furthermore, the system exhibi...
Source: International Journal of Biological Macromolecules - April 16, 2024 Category: Biochemistry Authors: Patricia Tello Jenifer Santos V íctor M Perez-Puyana Alberto Romero Luis A Trujillo-Cayado Source Type: research

Corrigendum to "A self-gelling powder based on polyacrylic acid/polyacrylamide/quaternate chitosan for rapid hemostasis" [Int. J. Biol. Macromol. 232 (2023) 123449]
Int J Biol Macromol. 2024 Apr 15;267(Pt 1):131532. doi: 10.1016/j.ijbiomac.2024.131532. Online ahead of print.NO ABSTRACTPMID:38626584 | DOI:10.1016/j.ijbiomac.2024.131532 (Source: International Journal of Biological Macromolecules)
Source: International Journal of Biological Macromolecules - April 16, 2024 Category: Biochemistry Authors: Zhouying Tan Xi Li Chaojie Yu Mengmeng Yao Zhongming Zhao Bingyan Guo Lei Liang Yuping Wei Fanglian Yao Hong Zhang Junjie Li Source Type: research

Thymosin beta 10 loaded ZIF-8/sericin hydrogel promoting angiogenesis and osteogenesis for bone regeneration
Int J Biol Macromol. 2024 Apr 14:131562. doi: 10.1016/j.ijbiomac.2024.131562. Online ahead of print.ABSTRACTAngiogenesis is pivotal for osteogenesis during bone regeneration. A hydrogel that promotes both angiogenesis and osteogenesis is essential in bone tissue engineering. However, creating scaffolds with the ideal balance of biodegradability, osteogenic, and angiogenic properties poses a challenge. Thymosin beta 10 (TMSB10), known for its dual role in angiogenesis and osteogenesis differentiation, faces limitations due to protein activity preservation. To tackle this issue, ZIF-8 was engineered as a carrier for TMSB10 (...
Source: International Journal of Biological Macromolecules - April 16, 2024 Category: Biochemistry Authors: Jia Gao Jing Ren Hanjie Ye Wenhui Chu Xuankai Ding Lingzhi Ding Yongqian Fu Source Type: research

Role of acemannan and pectic polysaccharides in saline-water stress tolerance of Aloe vera (Aloe barbadensis Miller) plant
This study investigates the impact of water and salinity stress on Aloe vera, focusing on the role of Aloe vera polysaccharides in mitigating these stresses. Pectins and acemannan were the most affected polymers. Low soil moisture and high salinity (NaCl 80 mM) increased pectic substances, altering rhamnogalacturonan type I in Aloe vera gel. Aloe vera pectins maintained a consistent 60 % methyl-esterification regardless of conditions. Interestingly, acemannan content rose with salinity, particularly under low moisture, accompanied by 90 to 150 % acetylation increase. These changes improved the functionality of Aloe vera po...
Source: International Journal of Biological Macromolecules - April 16, 2024 Category: Biochemistry Authors: Francesca Comas-Serra Jos é Luis Miró M ónica M Umaña Rafael Minjares-Fuentes Antoni Femenia Mar ía Mota-Ituarte Aurelio Pedroza-Sandoval Source Type: research

Metabolic activation and cytochrome P450 inhibition of piperlonguminine mediated by CYP3A4
This study characterized the O-dealkylated metabolite (M1) through chemical synthesis. The IC50 shift assay showed time-dependent inhibition of CYP3A4, 2C9, 2E1, 2C8 and 2D6 by PLG. This research contributes to the understanding of PLG-induced enzyme inhibition and bioactivation.PMID:38626834 | DOI:10.1016/j.ijbiomac.2024.131502 (Source: International Journal of Biological Macromolecules)
Source: International Journal of Biological Macromolecules - April 16, 2024 Category: Biochemistry Authors: Yuqian Chi Xiaoliang Zhu Yaxuan Chen Xin Li Ziyi Jiang Xiaoyang Jian Mengyuan Lian Xiaodi Wu Lei Wang Mengmeng Sun Xiaowei Shi Source Type: research

Effect of branched 1,4-butanediol citrate oligomers with different molecular weights on toughness and aging resistance of glycerol plasticized starch
In this study, branched 1,4-butanediol citrate oligomers with different molecular weights (P1, P2, and P3) are synthesized, and then mixed with glycerol (G) as the co-plasticizers to prepare thermoplastic starch (CS/PG). The results show that the molecular weight and branching degree of the branched 1,4-butanediol citrate oligomers increase as reaction time prolongs. Compared with glycerol plasticized starch, the thermoplastic starch films with branched 1,4-butanediol citrate oligomers/glycerol (10 wt%/20 wt%) have a better toughness, transmittance, and aging resistance, and have a lower crystallinity, hygroscopicity, and ...
Source: International Journal of Biological Macromolecules - April 16, 2024 Category: Biochemistry Authors: Haishun Ouyang Dongliang Jin Yixuan He Kewen Tang Xiaoming Guo Yi Lin Fei Cheng Puxin Zhu Dacheng Wu Kang Zhang Source Type: research

Stretchable, antifatigue, and intelligent nanocellulose hydrogel colorimetric film for real-time visual detection of beef freshness
In this study, a nanocellulose hydrogel colorimetric film with enhanced stretchability, antifatigue properties, and color stability was prepared using soy hull nanocellulose (SHNC), polyvinyl alcohol (PVA), sodium alginate (SA), and anthocyanin (Anth) as raw materials. This hydrogel colorimetric film was used to detect beef freshness. The structure and properties (e.g., mechanical, thermal stability and hydrophobicity) of these hydrogel colorimetric films were characterized using different techniques. Fourier-transform infrared spectroscopy revealed the presence of hydrogen and ester bonds in the hydrogel colorimetric film...
Source: International Journal of Biological Macromolecules - April 16, 2024 Category: Biochemistry Authors: Kejin Yu Lina Yang Siyu Zhang Ning Zhang Mengxi Xie Miao Yu Source Type: research

Preparation of pH-sensitive porous polylactic acid-based medical dressing with self-pumping function
In this study, we fabricated a pH-sensitive colorimetric chronic wound dressing with self-pumping function using electrostatic spinning technology. It consisted of three layers: a polylactic acid-curcumin (PCPLLA) hydrophobic layer, a hydrolyzed polyacrylonitrile (HPAN) transfer layer, and a polyacrylonitrile-purple kale anthocyanin (PAN-PCA) hydrophilic layer. The results showed that the preparation of porous PLLA fiber membrane loaded with 0.2 % Cur was achieved by adjusting the spinning-related parameters, which could ensure that the composite dressing had sufficient anti-inflammatory, antibacterial and antioxidant prop...
Source: International Journal of Biological Macromolecules - April 16, 2024 Category: Biochemistry Authors: Zijian Zhang Jianyong Li Yi Wang Xiaojie Wang Liming Wang Yinghua Qiu Fangyi Li Jianfeng Li Maocheng Ji Jia Man Source Type: research

Polyvinyl alcohol/chitosan quaternary ammonium salt composite hydrogel with directional macroporous structure for photothermal synergistic antibacterial and wound healing promotion
Int J Biol Macromol. 2024 Apr 14:131549. doi: 10.1016/j.ijbiomac.2024.131549. Online ahead of print.ABSTRACTAfter skin tissue trauma, wound infections caused by bacteria posed a great threat to skin repair. However, resistance to antibiotics, the current treatment of choice for bacterial infections, greatly affected the efficiency of anti-infection and wound healing. Therefore, there has been a critical need for the development of novel antimicrobial materials and advanced therapeutic methods to aid in skin repair. In this paper, rGO-PDA@ZIF-8 nanofillers were prepared by coating graphene oxide (GO) with dopamine (DA), fol...
Source: International Journal of Biological Macromolecules - April 16, 2024 Category: Biochemistry Authors: Xianyu Lan Hang Yang Yuzhu Xiong Guanyue Zeng Fuping Dong Source Type: research

The effect of EGCG/tyrosol-loaded chitosan/lecithin nanoparticles on hyperglycemia and hepatic function in streptozotocin-induced diabetic mice
In conclusion, the EGCG/tyrosol-loaded C/L NPs reduced hyperglycemia, oxidative stress, and inflammation in diabetic mice. These findings suggest that EGCG/tyrosol-loaded C/L NPs could be a promising therapeutic option for type 2 diabetes management.PMID:38626839 | DOI:10.1016/j.ijbiomac.2024.131496 (Source: International Journal of Biological Macromolecules)
Source: International Journal of Biological Macromolecules - April 16, 2024 Category: Biochemistry Authors: Ali Es-Haghi Mozhgan Soltani Masoud Homayouni Tabrizi Maryam Karimi Noghondar Nilofar Khatamian Niloofar Barati Naeeni Matin Kharaghani Source Type: research

Characterization of emulgels formulated with phycocyanin and diutan gum as a novel approach for biocompatible delivery systems
Int J Biol Macromol. 2024 Apr 14:131599. doi: 10.1016/j.ijbiomac.2024.131599. Online ahead of print.ABSTRACTPhycocyanin (PC), a protein derived from algae, is non-toxic and biocompatible. Due to its environmental and sustainable properties, it has been studied as an alternative stabilizer for food emulsions. In this sense, the main objective of this work is to evaluate the effectiveness of PC and its use in combination with diutan gum (DG), a biological macromolecule, to prepare emulgels formulated with avocado oil. Z-potential measurements show that the optimum pH for working with PC is 2.5. Furthermore, the system exhibi...
Source: International Journal of Biological Macromolecules - April 16, 2024 Category: Biochemistry Authors: Patricia Tello Jenifer Santos V íctor M Perez-Puyana Alberto Romero Luis A Trujillo-Cayado Source Type: research