Effect of starch and peanut oil on physicochemical and gel properties of myofibrillar protein: Amylose content and addition form
Int J Biol Macromol. 2024 Apr 18:131699. doi: 10.1016/j.ijbiomac.2024.131699. Online ahead of print.ABSTRACTStarch and peanut oil (PO) were widely used to improve the gel properties of surimi, however, the impact mechanism of addition forms on the denaturation and aggregation behavior of myofibrillar protein (MP) is not clear. Therefore, the effect of starch, PO, starch/PO mixture, and starch-based emulsion on the physicochemical and gel properties of MP was investigated. The results showed that amylose could accelerate the aggregation of MP, while amylopectin was conducive to the improvement of gel properties. The additio...
Source: International Journal of Biological Macromolecules - April 20, 2024 Category: Biochemistry Authors: Hongbo Mi Nan Su Shangyun Liang Jianrong Li Jingxin Chen Xuepeng Li Source Type: research

Goat milk exosomal microRNAs alleviate LPS-induced intestinal inflammation in mice
In this study, the protective effect of goat milk exosomes on LPS-induced intestinal inflammation was investigated using mouse intestinal inflammation model and IEC-6 cell inflammation model. Small RNA sequencing was used to analyze the miRNA expression profile of goat milk exosomes. In this study, C-Exo and M-Exo alleviated intestinal inflammation by reducing the LPS-induced release of proinflammatory cytokines, inhibiting the increase in the NLRP3 protein and the activation of the TLR4/NFκB signaling pathway. C-Exo has a more significant inhibitory effect on them, and better therapeutic efficacy than M-Exo. Notably, the...
Source: International Journal of Biological Macromolecules - April 20, 2024 Category: Biochemistry Authors: Feng Gao Shenghui Wu Kang Zhang Zhiming Xu Fusheng Quan Source Type: research

Ganoderma lucidum: Multifaceted mechanisms to combat diabetes through polysaccharides and triterpenoids: A comprehensive review
Int J Biol Macromol. 2024 Apr 18:131644. doi: 10.1016/j.ijbiomac.2024.131644. Online ahead of print.ABSTRACTDiabetes is a chronic metabolic disorder. Diabetes complications can affect many organs and systems in the body. Ganoderma lucidum (G. lucidum) contains various compounds that have been studied for their potential antidiabetic effects, including polysaccharides, triterpenoids (ganoderic acids, ganoderol B), proteoglycans, and G. lucidum extracts. G. lucidum polysaccharides (GLPs) and triterpenoids have been shown to act through distinct mechanisms, such as improving glucose metabolism, modulating the mitogen-activate...
Source: International Journal of Biological Macromolecules - April 20, 2024 Category: Biochemistry Authors: Md Faruque Ahmad Fakhruddin Ali Ahmad Nazim Hasan Abdulrahman A Alsayegh Othman Hakami Farkad Bantun Shadma Tasneem Waleed M Alamie Ahmad O Babalghith Abdullah F Aldairi Nahla Kambal Ehab Y Elbendary Source Type: research

Formulation and application of poly lactic acid, gum, and cellulose-based ternary bioplastic for smart food packaging: A review
Int J Biol Macromol. 2024 Apr 18:131687. doi: 10.1016/j.ijbiomac.2024.131687. Online ahead of print.ABSTRACTIn future, global demand for low-cost-sustainable materials possessing good strength is going to increase tremendously, to replace synthetic plastic materials, thus motivating scientists towards green composites. The PLA has been the most promising sustainable bio composites, due to its inherent antibacterial property, biodegradability, eco-friendliness, and good thermal and mechanical characteristics. However, PLA has certain demerits such as poor water and gas barrier properties, and low glass transition temperatur...
Source: International Journal of Biological Macromolecules - April 20, 2024 Category: Biochemistry Authors: Sayani Mavai Aarti Bains Kandi Sridhar Summya Rashid Gehan M Elossaily Nemat Ali Prince Chawla Minaxi Sharma Source Type: research

A review of DNA nanoparticles-encapsulated drug/gene/protein for advanced controlled drug release: Current status and future perspective over emerging therapy approaches
Int J Biol Macromol. 2024 Apr 18:131694. doi: 10.1016/j.ijbiomac.2024.131694. Online ahead of print.ABSTRACTIn the last ten years, the field of nanomedicine has experienced significant progress in creating novel drug delivery systems (DDSs). An effective strategy involves employing DNA nanoparticles (NPs) as carriers to encapsulate drugs, genes, or proteins, facilitating regulated drug release. This abstract examines the utilization of DNA NPs and their potential applications in strategies for controlled drug release. Researchers have utilized the distinctive characteristics of DNA molecules, including their ability to sel...
Source: International Journal of Biological Macromolecules - April 20, 2024 Category: Biochemistry Authors: Ghazal Kadkhodaie Kashani Seyed Morteza Naghib Sina Soleymani M R Mozafari Source Type: research

Corrigendum to "An odorant binding protein mediates Bactrocera dorsalis olfactory sensitivity to host plant volatiles and male attractant compounds" [Int. J. Biol. Macromol. Vol. 219, 31 October 2022, pages 538-544]
Int J Biol Macromol. 2024 Apr 16;267(Pt 2):131296. doi: 10.1016/j.ijbiomac.2024.131296. Online ahead of print.NO ABSTRACTPMID:38631190 | DOI:10.1016/j.ijbiomac.2024.131296 (Source: International Journal of Biological Macromolecules)
Source: International Journal of Biological Macromolecules - April 17, 2024 Category: Biochemistry Authors: Zhao Liu Qian-Ping Xie Huai-Wang Guo Wei Xu Jin-Jun Wang Source Type: research

Conductometric investigation of nano MnSO < sub > 4 < /sub > association parameters and complex formation with glycylglycine in aqueous and methanol-water mixtures: Thermodynamic parameters and potential applications
This study aimed to investigate the ion pair association values and association parameters of nano MnSO4 in water and methanol-water mixtures (20 % and 40 % methanol by mass percentage) at varying temperatures (298.15, 303.15, 308.15, and 313.15 K) using the conductometric technique. Additionally, the parameters for complex formation between nano MnSO4 and glycylglycine as a ligand were determined. The focus was on elucidating the thermodynamic formation parameters for the nano Mn2+-glycylglycine interaction, with particular emphasis on comparing the 1: 1 and 1: 2 (M: L) complexes to understand the complexation behavior mo...
Source: International Journal of Biological Macromolecules - April 17, 2024 Category: Biochemistry Authors: Radwa T Rashad Hany A Nasef Esam A Gomaa Elsayed M AbouElleef Source Type: research

Development of innovative active packaging films using gelatin/pullulan-based composites incorporated with cinnamon essential oil-loaded metal-organic frameworks for meat preservation
This study aimed to investigate the effect of cinnamon essential oil (CEO)-loaded metal-organic frameworks (CEO@MOF) on the properties of gelatin/pullulan (Gel/Pull)-based composite films (Gel/Pull-based films). The incorporation of CEO@MOF into Gel/Pull-based films demonstrated significant antimicrobial activity against S. aureus, S. enterica, E. coli, and L. monocytogenes. Additionally, CEO@MOF integrated film exhibited a 98.16 % ABTS radical scavenging, with no significant change in the mechanical properties of the neat Gel/Pull film. The UV blocking efficiency of the composite films increased significantly from 81.38 t...
Source: International Journal of Biological Macromolecules - April 17, 2024 Category: Biochemistry Authors: Su Jung Hong Zohreh Riahi Gye Hwa Shin Jun Tae Kim Source Type: research

Application of gums as techno-functional hydrocolloids in meat processing and preservation: A review
This study explores the use of gums in meat and meat product processing and preservation. The water holding and emulsifying properties of gums can potentially bind fat and reduce overall lipid content, while their antimicrobial and film-forming properties can inhibit the microbial growth and reduce oxidation, thereby extending the shelf life. Incorporating gums as a fat replacer and edible coating shows promise for reducing fat content and extending the shelf life of meat and meat products.PMID:38631567 | DOI:10.1016/j.ijbiomac.2024.131614 (Source: International Journal of Biological Macromolecules)
Source: International Journal of Biological Macromolecules - April 17, 2024 Category: Biochemistry Authors: Xueqin Gao Hamidreza Pourramezan Yousef Ramezan Swarup Roy Wanli Zhang Elham Assadpour Jian Zou Seid Mahdi Jafari Source Type: research

"Flexible-strong" polylactic acid porous membrane via tailored polymerization degree of lactic acid side-chains grafting for passive daytime radiative cooler
Int J Biol Macromol. 2024 Apr 15:131653. doi: 10.1016/j.ijbiomac.2024.131653. Online ahead of print.ABSTRACTAerogel possesses the advantages of high specific surface area, low density, and high porosity, which have shown great application in thermal regulation due to its efficient light scattering capability. However, traditional polymer-based aerogels have poor mechanical properties and lack ductility in outdoor applications, the cooling efficiency of the material is easily affected by damage during transportation, installation, and environmental factors. In this work, combining the porous nature of aerogels and the high ...
Source: International Journal of Biological Macromolecules - April 17, 2024 Category: Biochemistry Authors: Yibo Wang Fulin Cheng Jing Liu Wanquan Cai Jiawen Ji Chenyang Cai Yu Fu Source Type: research

Biomass-derived cellulose nanocrystals modified nZVI for enhanced tetrabromobisphenol A (TBBPA) removal
This study indicated that fine-tuned fabrication of CNC/nZVI could potentially be a promising alternative for remediation of TBBPA-contaminated aquatic environments.PMID:38631569 | DOI:10.1016/j.ijbiomac.2024.131625 (Source: International Journal of Biological Macromolecules)
Source: International Journal of Biological Macromolecules - April 17, 2024 Category: Biochemistry Authors: Shiyan Li Xiaolei Hu Jie Zhou Shuo Zheng Quanxue Ma Haoyang Fu Wei-Xian Zhang Zilong Deng Source Type: research

Exploring the association of POSTN < sup > + < /sup > cancer-associated fibroblasts with triple-negative breast cancer
This study aimed to identify and characterize a specific subtype of CAFs associated with TNBC. Initially, using high-throughput bulk transcriptomic data in two cohorts, we identified three CAF-related subtypes (CS1, CS2, CS3) in TNBC samples. These three CAFs subtypes were closely linked to the tumor microenvironment. The CS1 subtype exhibited a relatively immune-rich microenvironment and a favourable prognosis, whereas the CS3 subtype displayed an immune-deprived tumor microenvironment and an unfavourable prognosis. Through WGCNA analysis, POSTN was identified as a key biomarker for CAFs associated with TNBC. Then, POSTN+...
Source: International Journal of Biological Macromolecules - April 17, 2024 Category: Biochemistry Authors: Shuangyan Lin Miaoni Zhou Liying Cheng Zhifeng Shuai Mingyuan Zhao Ruixia Jie Qun Wan Fang Peng Qiang Shu Shiping Ding Source Type: research

Structural identification and anti-neuroinflammatory effects of a pectin-arabinoglucuronogalactan complex, AOPB-1-1, isolated from Asparagus officinalis
Int J Biol Macromol. 2024 Apr 15:131593. doi: 10.1016/j.ijbiomac.2024.131593. Online ahead of print.ABSTRACTAsparagus officinalis L. is a horticultural crop that contains a variety of bioactive compounds with anti-inflammatory effects. Aqueous extracts of A. officinalis can noticeably improve the learning and memory function of model mice. Herein, a pectin-arabinoglucuronogalactan complex (AOPB-1-1) with a relative molecular weight of 90.8 kDa was isolated from A. officinalis. The repeating structural unit of AOPB-1-1 was identified through monosaccharide composition, methylation analysis, uronic acid reduction, partial ac...
Source: International Journal of Biological Macromolecules - April 17, 2024 Category: Biochemistry Authors: Junqiang Yang Yuechan Liao Chao Cao Qian Yu Dawei Zhang Chunyan Yan Source Type: research

Preparation and application of halogen-free and efficient Si/P/N-containing flame retardants on cotton fabrics
Int J Biol Macromol. 2024 Apr 15:131612. doi: 10.1016/j.ijbiomac.2024.131612. Online ahead of print.ABSTRACTCotton fabric is extensively utilized due to its numerous applications, but the flammability associated with cotton fabric poses potential security risks to individuals. A halogen-free efficient flame retardant named poly [(tetramethylcyclosiloxyl spirocyclic pentaerythritol)-piperazin phosphate] (PCPNTSi) was developed to consolidate the fire retardance of cotton fabrics. After PCPNTSi treatment, the limiting oxygen index (LOI) of cotton fabric with 30 % weight gain (CP3) was raised to 32.8 %. In the vertical flamma...
Source: International Journal of Biological Macromolecules - April 17, 2024 Category: Biochemistry Authors: Shuangshaung Zhang Chen Chen Dezheng Kong Yufan Zhang Kexian Liu Meng Shi Chaohong Dong Zhou Lu Source Type: research

Enhanced environmental stress resistance and functional properties of the curcumin-shellac nano-delivery system: Anti-flocculation of poly- γ-glutamic acid
Int J Biol Macromol. 2024 Apr 15:131607. doi: 10.1016/j.ijbiomac.2024.131607. Online ahead of print.ABSTRACTCurcumin was widely designed as nanoparticles to remove application restrictions. The occurrence of flocculation is a primary factor limiting the application of the curcumin nano-delivery system. To enhance the environmental stress resistance and functional properties of shellac-curcumin nanoparticles (S-Cur-NPs), γ-polyglutamic acid (γ-PGA) was utilized as an anti-flocculant. The encapsulation efficiency and loading capacity of S-Cur-NPs were also improved with γ-PGA incorporation. FTIR and XRD analysis confirmed...
Source: International Journal of Biological Macromolecules - April 17, 2024 Category: Biochemistry Authors: Di Zhuang Yafang Wang Shancan Wang Rui Li Hafiz Nabeel Ahmad Jie Zhu Source Type: research