Ecotoxicology and Environmental Safety 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Cadmium/zinc stresses and plant cultivation influenced soil microflora: a pot experiment conducted in field
In this study, the impacts of comfrey (Symphytum officinale L.) cultivation and the stresses of cadmium/zinc (Cd/Zn) on rhizosphere soil microflora were examined. Microbial DNA was collected from soils to evaluate the prevalence of bacteria and fungi communities in rhizosphere soils. High-throughput 16 S rRNA sequencing was used to determine the diversity of the bacterial and fungal communities. The results showed that growing comfrey on polluted soils reduced the levels of Cd and Zn from the vertical profile. Both the comfrey growth and Cd/Zn stresses affected the community of rhizosphere microorganisms (bacteria or fungi...
Source: Ecotoxicology and Environmental Safety - April 24, 2024 Category: Environmental Health Authors: Di Guo Kunkun Tian Xinyue Peng Shihao Liu Xixia Xu Wenwen Tian Source Type: research
Synergistic suppression of BDNF via epigenetic mechanism deteriorating learning and memory impairment caused by Mn and Pb co-exposure
Ecotoxicol Environ Saf. 2024 Apr 23;277:116365. doi: 10.1016/j.ecoenv.2024.116365. Online ahead of print.ABSTRACTMicroglia, the resident immune cells of the central nervous system (CNS), play a dual role in neurotoxicity by releasing the NLR Family Pyrin Domain Containing 3 (NLRP3) inflammasome and brain-derived neurotrophic factor (BDNF) in response to environmental stress. Suppression of BDNF is implicated in learning and memory impairment induced by exposure to manganese (Mn) or lead (Pb) individually. Methyl CpG Binding Protein 2 (MeCp2) and its phosphorylation status are related to BDNF suppression. Protein phosphatas...
Source: Ecotoxicology and Environmental Safety - April 24, 2024 Category: Environmental Health Authors: Lancheng Wei Hongjian He Shuting Yang Qianqian Shi Xinhang Wang Liyuan Huang Jianyong Lu Yinghui Shen Kaikai Zhi Junni Xiang Chengying Chen Jiao Mo Zhijian Zheng Yunfeng Zou Xiaobo Yang Shen Tang Xiyi Li Cailing Lu Source Type: research
Effect of magnetized water irrigation on Cd subcellular allocation and chemical forms in leaves of Festuca arundinacea during phytoremediation
This study evaluated variations in the Cd subcellular allocation and fractions in various F. arundinacea leaves, with or without magnetized water irrigation. Over 50 % of the metal were sequestered within the cell wall in all tissues under all treatments, indicating that cell wall binding was a critical detoxification pathway for Cd. After magnetized water treatment, the metal stored in the cytoplasm of roots raised from 33.1 % to 45.3 %, and the quantity of soluble Cd in plant roots enhanced from 53.4 % to 59.0 %. The findings suggested that magnetized water mobilized Cd in the roots, and thus drove it into the leaves. In...
Source: Ecotoxicology and Environmental Safety - April 24, 2024 Category: Environmental Health Authors: Jie Luo Siyao Feng Mingpo Li Yue He Yuping Deng Min Cao Source Type: research
Novel insights into antimony mobilization in different high- antimony aquifers from the molecular signatures of dissolved organic matter
This study aims to investigate the origins and molecular compositions of DOM in different high-Sb aquifers (Sb-mining and no-Sb-mining aquifer), as well as compare different molecular signatures of DOM and mechanisms for Sb migration. The findings showed that Sb concentrations in Sb-mining aquifer exhibited a positive correlation with lignin- and tannin-like molecules characterized by high O/C and low H/C ratios, indicating an increased abundance of aromatic components with higher Humification Index and SUV-absorbance at 254 nm, compared to no-Sb-mining aquifer. Correspondingly, the complexation and competitive adsorption ...
Source: Ecotoxicology and Environmental Safety - April 24, 2024 Category: Environmental Health Authors: Chunming Hao Qianqian Sun Ximeng Sun Qiong Li Source Type: research
PM < sub > 2.5 < /sub > exposure upregulates pro-inflammatory protein expression in human microglial cells via oxidant stress and TLR4/NF- κB pathway
In this study, a human microglial cell line (HMC3) was used as the in vitro model to examine the inflammatory effect (hall marker of microglia activation) of PM2.5 and regulatory pathways. The expression of inflammatory mediators including interleukin-6 (IL-6) and cyclooxygenase-2 (COX-2) as well as the brain derived neurotrophic factor (BDNF) were determined by ELISA and/or real-time PCR, respectively. Flow cytometry was used to measure the production of intracellular reactive oxygen species (ROS). Western blot was used to measure protein levels of Toll-like receptor 4 (TLR4), NF-κB inhibitor α (IκBα) and COX-2. It wa...
Source: Ecotoxicology and Environmental Safety - April 24, 2024 Category: Environmental Health Authors: Ling Zhang Fei Xu Yishu Yang Lin Yang Qiong Wu Han Sun Zhen An Juan Li Hui Wu Jie Song Weidong Wu Source Type: research
Curcumin alleviates zearalenone-induced liver injury in mice by scavenging reactive oxygen species and inhibiting mitochondrial apoptosis pathway
In conclusion, CUR alleviated ZEN-induced liver injury in mice by scavenging ROS and inhibiting the mitochondrial apoptotic pathway.PMID:38657456 | DOI:10.1016/j.ecoenv.2024.116343 (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - April 24, 2024 Category: Environmental Health Authors: Xiaopeng Yang Hao Zheng Junlong Niu Xiaoshuang Chen Hongfei Li Zhiyong Rao Yongpeng Guo Wei Zhang Zhixiang Wang Source Type: research
Fates and models for exposure pathways of pyrethroid pesticide residues: A review
Ecotoxicol Environ Saf. 2024 Apr 23;277:116342. doi: 10.1016/j.ecoenv.2024.116342. Online ahead of print.ABSTRACTPyrethroids (PYs) are widely applied pesticides whose residues pose potential health risks. This review describes current knowledge on PY chemical properties, usage patterns, environmental and food contamination, and human exposure models. It evaluates life cycle assessment (LCA), chemical alternatives assessment (CAA), and high-throughput screening (HTS) as tools for pesticide policy. Despite efforts to mitigate PY presence, their pervasive residues in the environment and food persist. And the highest concentra...
Source: Ecotoxicology and Environmental Safety - April 24, 2024 Category: Environmental Health Authors: Shan Liu Jisha Yan Bowen Xu Xinyi Huang Haixiong Qin Jiayuan Zhao Chen Xia Shen Yan Gang Liu Source Type: research
Polystyrene exposure induces lamb gastrointestinal injury, digestive disorders and inflammation, decreasing daily gain, and meat quality
In conclusion, PS-exposure inhibited lambs' digestive function, adversely affects blood and organs' health status, reducing average daily gain and negatively influencing meat quality. PS particles of 50-100 μm bring worse damage to lambs. This research aims to fill the knowledge void concerning MPs' influences on ruminant animals, with a specific focus on the meat quality of fattening lambs.PMID:38657458 | DOI:10.1016/j.ecoenv.2024.116389 (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - April 24, 2024 Category: Environmental Health Authors: Xiao Chang Yan Li Yujie Han Yi Fang Hai Xiang Zijiao Zhao Bao Zhao Rongzhen Zhong Source Type: research
The characteristics of fungal responses to uranium mining activities and analysis of their tolerance to uranium
This study provides insights into the impact of U mining on soil fungal stability and the response of fungi to U mining activities, as well as aids in the screening of fungal strains that can be used to promote remediation of U mining sites on plateaus.PMID:38657459 | DOI:10.1016/j.ecoenv.2024.116362 (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - April 24, 2024 Category: Environmental Health Authors: Lu Qiu Ajia Sha Na Li Yanqiong Ran Peng Xiang Lin Zhou Ting Zhang Qian Wu Liang Zou Zhaoqiong Chen Qiang Li Changsong Zhao Source Type: research
Study on the role of CCM3 gene and lead exposure induced neurotoxicity through neurovascular units
This study aimed to determine the toxic effects of vascular CCM3 gene deficiency and lead (Pb) exposure on the nervous system. Lentiviral transfection was performed to generate a stable strain of brain microvascular endothelial cells with low CCM3 expression. MTT assay assessed the survival rate of cells exposed to Pb, determining the dose and duration of Pb exposure in vitro. Proteomic analysis was performed on the differentially expressed proteins in bEnd3 and HT22 cells and flow cytometry was used to detect cell apoptosis. Finally, urine samples from pregnant and postpartum women were subjected to ICP-MS to detect Pb le...
Source: Ecotoxicology and Environmental Safety - April 24, 2024 Category: Environmental Health Authors: Yumeng Li Yun Liu Kangkang Liu Tao Tao Liuxue Yang Ruxi Liu Hang Zhou Dan Liang Ying Zhang Danni Huang Yi Sun Source Type: research
The antagonism mechanism of astilbin against cadmium-induced injury in chicken lungs via Treg/Th1 balance signaling pathway
In conclusion, our results suggest that astilbin treatment alleviated the effects of cadmium-mediated lung injury in chickens by restoring the Treg/Th1 balance.PMID:38657461 | DOI:10.1016/j.ecoenv.2024.116364 (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - April 24, 2024 Category: Environmental Health Authors: Guangliang Shi Tiange Tai Yusong Miao Liangchun Yan Tianyu Han Han Dong Zhaoyang Liu Tingting Cheng Yiding Liu Yu Yang Shanshan Fei Bo Pang Tiezhu Chen Source Type: research
Genome-wide DNA methylation changes in Oryzias melastigma embryos exposed to the water accommodated fraction of crude oil
Ecotoxicol Environ Saf. 2024 Apr 22;277:116325. doi: 10.1016/j.ecoenv.2024.116325. Online ahead of print.ABSTRACTThe water accommodated fraction (WAF) of crude oil exerts considerable impacts on marine fish during embryonic stage. Clarifying changes in epigenetic modifications is helpful for understanding the molecular mechanism underlying the toxicity of embryonic WAF exposure. The aim of this study was to explore genome-wide DNA methylation changes in Oryzias melastigma embryos after exposure to the nominal total petroleum hydrocarbon concentration of 500 μg/L in WAF for 7 days. Whole-genome bisulfite sequencing reveale...
Source: Ecotoxicology and Environmental Safety - April 23, 2024 Category: Environmental Health Authors: Chenshi Wang Wei Lei Lichao Du Yiran Xu Yingbin Lou Mo Peng Dongxu Gao Source Type: research
Effect of zeolites on the reduction of the ecotoxicity of carbamazepine in the environment
In this study, the impact of calcination of zeolites on the ecotoxicity of carbamazepine solutions in two matrices, water and synthetic sewage, was assessed. Two types of zeolites were tested: natural zeolite, in the form of a zeolite rock consisting mainly of clinoptilolite, and a synthetic zeolite type 5 A. Additionally, zeolites were calcined at a temperature of 200 °C. The kinetics of carbamazepine adsorption in aqueous solutions and in synthetic sewage matrix was determined. Higher adsorption capacity was obtained for carbamazepine aqueous solutions as well as zeolites after the calcination process. Considering type ...
Source: Ecotoxicology and Environmental Safety - April 23, 2024 Category: Environmental Health Authors: Aleksandra Bogusz Beata Tomczyk Magdalena Trzci ńska Barbara Miros ław Barbara Gworek Source Type: research
Associations of dichlorophenols, trichlorophenols, and ortho-phenylphenol with the risk and prognosis of diabetes and prediabetes: A population-based study
Ecotoxicol Environ Saf. 2024 Apr 22;277:116345. doi: 10.1016/j.ecoenv.2024.116345. Online ahead of print.ABSTRACT2,4-dichlorophenol (2,4-DCP), 2,5-DCP, 2,4,5-trichlorophenol (2,4,5-TCP), 2,4,6-TCP, and ortho-phenylphenol (OPP) are widely present in the environment. However, their associations with risk and prognosis of diabetes and prediabetes remains unclear. We investigated the associations of these five phenols with the risk of diabetes and prediabetes, and with all-cause and cardiovascular disease (CVD) mortality, in adults with diabetes or prediabetes (n=6419). Information on diabetes and prediabetes indicators, and m...
Source: Ecotoxicology and Environmental Safety - April 23, 2024 Category: Environmental Health Authors: Jiayin Ou Ronghui Xian Jiayu Li Jianhe Zhao Kaiyao Zhang Peishan Mo Jiansong Fang Yue Shen Xiaoling Hu Shuhuan Fang Wei Liu Huafeng Pan Source Type: research
Environmental pollutants and male infertility: Effects on CatSper
Ecotoxicol Environ Saf. 2024 Apr 22;277:116341. doi: 10.1016/j.ecoenv.2024.116341. Online ahead of print.ABSTRACTInfertility is a growing health concern among many couples worldwide. Men account for half of infertility cases. CatSper, a sperm-specific Ca2+ channel, is expressed on the cell membrane of mammalian sperm. CatSper plays an important role in male fertility because it facilitates the entry of Ca2+ necessary for the rapid change in sperm motility, thereby allowing it to navigate the hurdles of the female reproductive tract and successfully locate the egg. Many pollutants present in the environment have been shown ...
Source: Ecotoxicology and Environmental Safety - April 23, 2024 Category: Environmental Health Authors: Yuxin He Binhui Wang Jian Huang Dalei Zhang Yangyang Yuan Source Type: research
