Single-cell transcriptomics uncovers phenotypic alterations in the monocytes in a Chinese population with chronic cadmium exposure.
CONCLUSION: This transcriptomic analysis provides molecular information about how the most important hallmarks of immune cell dysfunction are affected by plasma cadmium level. The significant phenotypic alterations in monocytes serving as early indicators of increased susceptibility to infectious and malignant diseases. PMID: 33444878 [PubMed - as supplied by publisher] (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - January 11, 2021 Category: Environmental Health Authors: Lu Y, Wu J, Gu W, Huang Z, Shu Z, Huang M, Chen J, Zhou M, Bai Y, Chen X, Xiao Y, Shen M, Luo D, Deng Q, Chai L, He M, Gong J, Yuan H, Xu Q, Cai J Tags: Ecotoxicol Environ Saf Source Type: research

Novel insights into cytochrome P450 enzyme and solute carrier families in cadmium-induced liver injury of pigs.
In conclusion, Cd could cause liver injury in weanling piglets and change the transcriptomic characteristics of liver. CYP450 and SLC families play an indispensable role in Cd-mediated hepatotoxicity. Importantly, changes in mRNA levels of CYP2B22, CYP7A1, CYP8B1, SLC26A8, SLC11A1, SLC27A2 and SLC22A7 induced by Cd have been reported for the first time. Our findings will provide a new insight for better assessing the mechanism of Cd toxicity to the liver. PMID: 33444879 [PubMed - as supplied by publisher] (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - January 11, 2021 Category: Environmental Health Authors: Wang H, Han Q, Chen Y, Hu G, Xing H Tags: Ecotoxicol Environ Saf Source Type: research

Identification and functional analysis of senescence-associated secretory phenotype of premature senescent hepatocytes induced by hexavalent chromium.
Abstract Hexavalent chromium [Cr(VI)] is a common heavy metal pollutant that can cause a number of human disease, including inflammation and cancer. Senescent cells can secrete a variety of molecules known as senescence-associated secretory phenotype (SASP). Our previous studies have confirmed that Cr(VI) can induce premature senescence in L02 hepatocytes, but the composition and the function of the related SASP are still unknown. In order to understand the components of SASP secreted by senescent L02 hepatocytes under the action of Cr(VI), we applied LC-MS/MS-based label-free protein quantification. We found that...
Source: Ecotoxicology and Environmental Safety - January 10, 2021 Category: Environmental Health Authors: Ma Y, Liang Y, Liang N, Zhang Y, Xiao F Tags: Ecotoxicol Environ Saf Source Type: research

Gold nanoparticles synergize with bacterial lipopolysaccharide to enhance class A scavenger receptor dependent particle uptake in neutrophils and augment neutrophil extracellular traps formation.
In this study, we demonstrated a size-dependent effect of AuNPs to synergize with bacterial lipopolysaccharide (LPS) in promoting neutrophil extracellular traps (NETs) release in human peripheral neutrophils. Mechanistically, LPS was more efficient to contact with 10 nm AuNPs and promote their uptake in neutrophils compared to 40 and 100 nm AuNPs, leading to a synergistic upregulation of class A scavenger receptor (SRA) which mediated AuNPs uptake and triggered activation of extracellular regulated protein kinase (ERK) and p38. Blocking SRA or inhibiting ERK and p38 activation remarkably abrogated the effect of A...
Source: Ecotoxicology and Environmental Safety - January 10, 2021 Category: Environmental Health Authors: Yang Y, Wang N, Zhu Y, Lu Y, Chen Q, Fan S, Huang Q, Chen X, Xia L, Wei Y, Zheng J, Liu X Tags: Ecotoxicol Environ Saf Source Type: research

Effect of maduramicin on crayfish (Procambius clarkii): Hematological parameters, oxidative stress, histopathological changes and stress response.
In conclusion, our findings demonstrated that environmental exposure of maduramicin threaten to the health of crayfish living in the areas nearby livestock farms or pharmaceutical factory. Crayfish exhibited resistance to the stress of maduramicin via activating drug metabolite and detoxification pathways. PMID: 33440267 [PubMed - as supplied by publisher] (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - January 10, 2021 Category: Environmental Health Authors: Gao X, Liu X, Song X, Teng P, Ji H, Peng L, Qiu Y, Guo D, Jiang S Tags: Ecotoxicol Environ Saf Source Type: research

In situ barium phytoremediation in flooded soil using Typha domingensis under different planting densities.
Abstract The management of initial planting density can be a strategy to increase barium phytoextraction from soil, reducing the time required for soil decontamination. To delimit the ideal planting density for barium (Ba) phytoremediation using Typha domingensis, we conducted a 300-day experiment in an area accidentally contaminated with barite. Four initial planting densities were tested: 4, 8, 12, and 16 plantsm-2 (D4, D8, D12, and D16 treatments, respectively). Plant development was evaluated periodically, and the phytoextraction efficiency was determined at the end of the trial. The initial planting density a...
Source: Ecotoxicology and Environmental Safety - January 10, 2021 Category: Environmental Health Authors: Viana DG, Egreja Filho FB, Pires FR, Soares MB, Ferreira AD, Bonomo R, Martins LF Tags: Ecotoxicol Environ Saf Source Type: research

Ammonia exposure causes the disruption of the solute carrier family gene network in pigs.
In conclusion, ammonia exposure can cause pathological changes in many tissues and organs of fattening pigs and changes in the SCL family gene network. Importantly, the SCL family is involved in the toxic mechanism of ammonia. Our findings will provide a new insight for better assessing the mechanism of ammonia toxicity. PMID: 33440271 [PubMed - as supplied by publisher] (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - January 10, 2021 Category: Environmental Health Authors: Xia C, Zhang X, Zhang Y, Li J, Xing H Tags: Ecotoxicol Environ Saf Source Type: research

Corrigendum to 'Phase-1 bioactivation mechanisms of aflatoxin through AhR, CAR and PXR nuclear receptors and the interactions with Nigella sativa seeds and thymoquinone in broilers' [Ecotoxicol. Environ. Saf. 208 (2021) 11174].
PMID: 33434706 [PubMed - as supplied by publisher] (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - January 9, 2021 Category: Environmental Health Authors: Ates MB, Ortatatli M Tags: Ecotoxicol Environ Saf Source Type: research

A low-volume air sampling method for legacy and novel brominated flame retardants in indoor environment using a newly developed sorbent mixture.
This study provides a new option of low-volume air sampling device using cartridges with a sorbent mixture for different types of legacy and novel BFRs. In this study, we found that HC-C18 sorbent is most suitable for polybrominated diphenyl ethers (PBDEs) and novel BFRs (NBFRs) enrichment, and that NH2 for hexabromocyclododecanes (HBCDs). The sorbent mixture was optimized using a complex of HC-C18 and NH2 sorbents with elution recovery of 69.4% ± 7.9-117% ± 10%, pumping-through recovery of 84.5% ± 7.9-127% ± 36%, and breakthrough recovery of 70.8% &p...
Source: Ecotoxicology and Environmental Safety - January 8, 2021 Category: Environmental Health Authors: Wang Y, Yang X, Liu Y, Zhang Q, Xiao H, Wang Y, Yao Y, Sun H Tags: Ecotoxicol Environ Saf Source Type: research

One step extraction followed by HPLC-ESI-MS/MS for multi-residue analysis of diacylhydrazine insecticides in water, sediment, and aquatic products.
Abstract A multi-residue analysis of six diacylhydrazine insecticides in water, sediment, and aquatic products was established by liquid chromatography triple quadrupole tandem mass spectrometry (LC-MS/MS). The water sample was extracted with acetonitrile by low-temperature enrichment liquid-liquid extraction technology. The sediment and aquatic products were prepared using QuEChERS technique. Method validation showed perfect linearity with correlation coefficients (R) more than 0.9992 for all insecticides, and the matrix effects were nearly negligible (-1.42% to -0.27%) for water, sediment and aquatic products. T...
Source: Ecotoxicology and Environmental Safety - January 8, 2021 Category: Environmental Health Authors: Gan J, Liu H, Chen Y, Peng J, Liu T, Chen J, He L Tags: Ecotoxicol Environ Saf Source Type: research

Prospective association of metal levels with gestational diabetes mellitus and glucose: A retrospective cohort study from South China.
Abstract OBJECTIVE: To explore the prospective correlation between serum metals before 24 weeks' gestation and gestational diabetes mellitus (GDM) or glucose in the late second trimester among southern Chinese pregnant women. METHODS: A total of 8169 pregnant women were included in our retrospective cohort study. Logistic regression was used to investigate the relationships between metals (Manganese [Mn], copper [Cu], lead [Pb], calcium [Ca], zinc [Zn], magnesium [Mg]) and GDM. Quantile regression was performed to detect the shifts and associations with metals and three time-points glucose distribution of ora...
Source: Ecotoxicology and Environmental Safety - January 8, 2021 Category: Environmental Health Authors: Zhou Z, Chen G, Li P, Rao J, Wang L, Yu D, Lin D, Fan D, Ye S, Wu S, Gou X, Wang H, Guo X, Lin L, Suo D, Liu Z Tags: Ecotoxicol Environ Saf Source Type: research

Exposure to different fractions of diesel exhaust PM2.5 induces different levels of pulmonary inflammation and acute phase response.
Abstract AIM: Ambient fine particulate matter (PM2.5) consists of various components, and their respective contributions to the toxicity of PM2.5 remains to be determined. To provide specific recommendations for preventing adverse effects due to PM2.5 pollution, we determined whether the induction of pulmonary inflammation, the putative pathogenesis for the morbidity and mortality due to PM2.5 exposure, was fractioned through solubility-dependent fractioning. METHODS: In the present study, the water and heptane solubilities-dependent serial fractioning of diesel exhaust particulate matter (DEP), a prominent s...
Source: Ecotoxicology and Environmental Safety - January 8, 2021 Category: Environmental Health Authors: Tao S, Xu Y, Chen M, Zhang H, Huang X, Li Z, Pan B, Peng R, Zhu Y, Kan H, Li W, Ying Z Tags: Ecotoxicol Environ Saf Source Type: research

Benzo[a]pyrene induces fibrotic changes and impairs differentiation in lung stem cells.
Abstract Human activities have generated air pollution, with extremely small particles (PM 2.5, particulate matter less than 2.5 µm in diameter) and liquid droplets, which become a menace to human health. Among the pollutants, polycyclic aromatic hydrocarbons (PAHs), which enhance the risks of pulmonary dysfunction and cancer development, have been extensively studied. Numerous studies have addressed the effects of PAHs on the respiratory system, whereas the effects on lung stem/progenitor cells remain unknown. Here, we provide evidence that benzo[a]pyrene (BaP), a major toxic PAH, induces fibrotic chan...
Source: Ecotoxicology and Environmental Safety - January 8, 2021 Category: Environmental Health Authors: Tseng YH, Chen YC, Yu AL, Yu J Tags: Ecotoxicol Environ Saf Source Type: research

Gallic acid improves the antioxidant ability against cadmium toxicity: Impact on leaf lipid composition of sunflower (Helianthus annuus) seedlings.
Abstract In the present work, the effect of seed pre-soaking with gallic acid (GA; 3,4,5-triphydroxyl-benzoic acid) in conferring subsequent tolerance to Cd stress in sunflower (Helianthus annuus) seedlings was investigated. Exposing sunflower seedlings to increasing Cd concentrations (5, 10 and 20 μM) caused a gradual decrease in root and shoot biomass and increased the metal accumulation in both organs. Seed pretreatment with 75 µM GA significantly restricted Cd uptake, markedly alleviated Cd-induced plant growth inhibition, and mitigated the oxidative damages caused by this metal, as compared...
Source: Ecotoxicology and Environmental Safety - January 8, 2021 Category: Environmental Health Authors: Saidi I, Guesmi F, Kharbech O, Hfaiedh N, Djebali W Tags: Ecotoxicol Environ Saf Source Type: research

Development of a rapid electrophoretic assay for genomic DNA damage quantification.
Abstract Accuracy, sensitivity, simplicity, reproducibility, and low-cost are desirable requirements for genotoxicity assessment techniques. Here we describe a simple electrophoretic assay for genomic DNA lesions quantification (EAsy-GeL) based on subjecting DNA samples to rapid unwinding/renaturation treatments and neutral agarose gel electrophoresis. The experiments performed in this work involved different biological samples exposed to increasing environmental-simulated doses of ultraviolet-B (UVB) radiation, such as Escherichia coli, human leukocytes, and isolated human genomic DNA. DNA extraction was carried ...
Source: Ecotoxicology and Environmental Safety - January 8, 2021 Category: Environmental Health Authors: Londero JEL, Schavinski CR, Silva FDD, Piccoli BC, Schuch AP Tags: Ecotoxicol Environ Saf Source Type: research

Expression of DNA repair genes in arctic char (Salvelinus alpinus) from Bj ørnøya in the Norwegian Arctic.
Expression of DNA repair genes in arctic char (Salvelinus alpinus) from Bjørnøya in the Norwegian Arctic. Ecotoxicol Environ Saf. 2021 Jan 08;210:111846 Authors: Inderberg H, Neerland ED, McPartland M, Sparstad T, Bytingsvik J, Nikiforov VA, Evenset A, Krøkje Å Abstract High levels of organochlorines (OCs) have been measured in arctic char (Salvelinus alpinus) from Lake Ellasjøen on Bjørnøya, Norway (74.30°N, 19.0°E). In a nearby lake, Laksvatn, the OC-levels in arctic char were low. A previous study has shown that char from Ellasjøen had ...
Source: Ecotoxicology and Environmental Safety - January 8, 2021 Category: Environmental Health Authors: Inderberg H, Neerland ED, McPartland M, Sparstad T, Bytingsvik J, Nikiforov VA, Evenset A, Krøkje Å Tags: Ecotoxicol Environ Saf Source Type: research

A novel ternary heterogeneous TiO2/BiVO4/NaY-Zeolite nanocomposite for photocatalytic degradation of microcystin-leucine arginine (MC-LR) under visible light.
Abstract Microcystin-leucine arginine (MC-LR) is a carcinogenic toxin, produced by cyanobacteria. The release of this toxin into drinking water sources can threaten public health and environmental safety. Therefore, effective MC-LR removal from water resources is necessary. In the present study, the hydrothermal method was used to synthesize a novel ternary BiVO4/TiO2/NaY-Zeolite (B/T/N-Z) nanocomposite for MC-LR degradation under visible light. FESEM, FTIR, XRD, and DRS were performed for characterizing the nanocomposite structure. Also, the Response Surface Methodology (RSM) was applied to determine the impact o...
Source: Ecotoxicology and Environmental Safety - January 8, 2021 Category: Environmental Health Authors: Ebrahimi A, Jafari N, Ebrahimpour K, Karimi M, Rostamnia S, Behnami A, Ghanbari R, Mohammadi A, Rahimi B, Abdolahnejad A Tags: Ecotoxicol Environ Saf Source Type: research

Intratracheally instillated diesel PM2.5 significantly altered the structure and composition of indigenous murine gut microbiota.
In this study, C57BL/6J mice were exposed to diesel PM2.5 for 14 days via intratracheal instillation, and colon tissues and feces were harvested for microbiota analysis. Using high-throughput sequencing technology, we observed that intratracheally instillated diesel PM2.5 significantly altered the gut microbiota diversity and community. At the phylum and genus levels, principal coordinate analysis (PCoA) and principal component analysis (PCA) indicated pronounced segregation of microbiota compositions, which were further confirmed by β diversity analysis. As the most affected phylum, Bacteroidetes was greatly diminish...
Source: Ecotoxicology and Environmental Safety - January 8, 2021 Category: Environmental Health Authors: Liu Y, Wang T, Si B, Du H, Liu Y, Waqas A, Huang S, Zhao G, Chen S, Xu A Tags: Ecotoxicol Environ Saf Source Type: research

"Ecotoxicol Environ Saf"[ta]; +178 new citations
178 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Ecotoxicol Environ Saf"[ta] These pubmed results were generated on 2021/01/06PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - January 7, 2021 Category: Environmental Health Tags: Report Source Type: research

Regulatory developments and their impacts to the nano-industry: A case study for nano-additives in 3D printing.
Abstract Nanotechnology has increasing applications in numerous markets, particularly in additive processing (3D printing) and manufacturing, which is important for consumer products, medical devices, construction, and general research and development across many other industries. Nanomaterials are desirable in many products due to their unique properties, but those same properties have made evaluating the risk and regulation of these materials challenging. For risk-based regulations, new applications and nanomaterials should be assessed for both human and environmental hazards and exposure to ensure protection. I...
Source: Ecotoxicology and Environmental Safety - December 3, 2020 Category: Environmental Health Authors: Taylor AA, Freeman EL, van der Ploeg MJC Tags: Ecotoxicol Environ Saf Source Type: research

Relationship of arsenic and chromium availability with carbon functional groups, aluminum and iron in Little Washita River Experimental Watershed Reservoirs, Oklahoma, USA.
Abstract Sediment from three reservoirs located in the Little Washita River Experimental Watershed (LWREW) in Oklahoma, USA with contrasting dominant land uses were analyzed for total and extractable concentrations of arsenic (As) and chromium (Cr), and the potential ecologic risk to benthic organisms. Extractable As ranged from 0.24 to 1.21 mg kg-1, in the order grazing>cropland>forest and 0.13-0.58 mg kg-1 for extractable Cr, in the order of forest>grazing>cropland. However, only approximately forest. The sediment exhibited an alkaline pH (8.0-8.7). As sorption exhibited a positiv...
Source: Ecotoxicology and Environmental Safety - December 3, 2020 Category: Environmental Health Authors: Ngatia LW, De Oliveira LM, Betiku OC, Fu R, Moriasi DN, Steiner JL, Verser JA, Taylor RW Tags: Ecotoxicol Environ Saf Source Type: research

Cadmium induces epithelial-mesenchymal transition and migration of renal cancer cells by increasing PGE2 through a cAMP/PKA-COX2 dependent mechanism.
This study might contribute to understanding of the mechanism of Cd-induce progression of renal cancer and future studies on the prevention and therapy of renal cell carcinomas. PMID: 33254385 [PubMed - in process] (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - December 3, 2020 Category: Environmental Health Authors: Shi H, Sun X, Kong A, Ma H, Xie Y, Cheng D, Wong CKC, Zhou Y, Gu J Tags: Ecotoxicol Environ Saf Source Type: research

Dynamic transcriptome response in Meretrix meretrix to Aroclor 1254 exposure.
Abstract Polychlorinated biphenyls (PCBs) are well-known persistent organic pollutants; they have toxic effects on the immune system, reproductive system, and endocrine system by changing the metabolism of the body. To elucidate the underlying molecular mechanism, the clam Meretrix meretrix was exposed to 10 and 1000 ng/L Aroclor 1254 and natural seawater (control). Samples from clams exposed to natural seawater and those exposed to Aroclor 1254 for 1 and 3 days were individually collected for transcriptome analysis. After assembly, more than 535,157 transcripts with a mean length of 949 bp and an N50 le...
Source: Ecotoxicology and Environmental Safety - December 3, 2020 Category: Environmental Health Authors: Li Y, Liu S, Cheng H, Chen X, Shen X, Cai Y Tags: Ecotoxicol Environ Saf Source Type: research

Synergistic effects of Fe-Mn binary oxide for gaseous arsenic removal in flue gas.
Abstract High-efficient and economic sorbents are highly desired for arsenic (As) emission control in flue gas from coal-fired power plant. A series of Fe-Mn binary oxides were prepared by a facile method, and their behaviors for gaseous arsenic removal in flue gas were investigated. The binary oxide exhibited a remarkable synergistic effect for arsenic removal compared with Mn or Fe monometallic oxide. The possible effects of CO2, NO, SO2, and O2 on the removal performance were also studied. The adsorption ability was excellent and stable in simulated flue gas conditions. X-ray photoelectron spectroscopy (XPS) an...
Source: Ecotoxicology and Environmental Safety - December 3, 2020 Category: Environmental Health Authors: He KQ, Yuan CG, Jiang YH, Duan XL, Li Y, Shi MD Tags: Ecotoxicol Environ Saf Source Type: research

Biomass allocation strategies and Pb-enrichment characteristics of six dwarf bamboos under soil Pb stress.
This study examined the biomass allocation strategies and lead (Pb) enrichment characteristics of various dwarf bamboo tissues by the end of the growing season and explored their potential for phytoremediation of Pb stress in the soils. Six dwarf bamboo genotypes were treated with three levels (0, 300, and 1500 mg kg-1) of soil Pb stress. The majority of the bamboos adopted two biomass allocation strategies to adapt to Pb stress, namely, "reducing biomass allocation into new bamboo growth" and "increasing/stabilizing biomass allocation into rhizomes". Pb accumulation was highest in the roots, ...
Source: Ecotoxicology and Environmental Safety - December 3, 2020 Category: Environmental Health Authors: Cai X, Jiang M, Liao J, Yang Y, Li N, Cheng Q, Li X, Song H, Luo Z, Liu S Tags: Ecotoxicol Environ Saf Source Type: research

Exploring the liver fibrosis induced by deltamethrin exposure in quails and elucidating the protective mechanism of resveratrol.
This study investigated the potential molecular mechanism that DLM induced liver fibrosis in quails. Japanese quails received resveratrol (500 mg/kg) daily with or without DLM (45 mg/kg) exposure for 12 weeks. Histopathology, transmission electron microscopy, biochemical indexes, TUNEL, quantitative real-time PCR, and western blot analysis were performed. DLM exposure induced hepatic steatosis, oxidative stress, inflammation, and apoptosis. Most importantly, the Nrf2/TGF-β1/Smad3 signaling pathway played an important role on DLM-induced liver fibrosis in quails. Interestingly, the addition of resveratrol, an...
Source: Ecotoxicology and Environmental Safety - December 3, 2020 Category: Environmental Health Authors: Li S, Zheng X, Zhang X, Yu H, Han B, Lv Y, Liu Y, Wang X, Zhang Z Tags: Ecotoxicol Environ Saf Source Type: research

Chemical stability of xanthates, dithiophosphinates and hydroxamic acids in aqueous solutions and their environmental implications.
In this study, the chemical stability of three xanthates of different alkyl groups (sodium ethyl xanthate (SEX), sodium isopropyl xanthate (SIPX) and potassium amyl xanthate (PAX)) was evaluated by UV/Vis spectroscopy, as a function of pH and time. Similarly, the chemical stability of three chelating collectors was evaluated: sodium di-isobutyl dithiophosphinate (SDIBDTPI), benzohydroxamic acid (BHA) and octanohydroxamic acid (OHA). Likewise, the surface tension of their aqueous solutions was measured making use of the Du Noüy method, to determine the critical micelle concentration (CMC). The results showed that the x...
Source: Ecotoxicology and Environmental Safety - December 3, 2020 Category: Environmental Health Authors: Elizondo-Álvarez MA, Uribe-Salas A, Bello-Teodoro S Tags: Ecotoxicol Environ Saf Source Type: research

Resveratrol alleviates zea-induced decidualization disturbance in human endometrial stromal cells.
This study provides novel insights into the mechanism underlying adverse effects of ZEA in human decidual stromal cells and suggests RSV a potential therapeutic candidate to alleviate ZEA-induced cytotoxicity during decidualization. PMID: 33254391 [PubMed - in process] (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - December 3, 2020 Category: Environmental Health Authors: Yao S, Wei W, Cao R, Lu L, Liang S, Xiong M, Zhang C, Liang X, Ma Y Tags: Ecotoxicol Environ Saf Source Type: research

A characterization of groundwater fluoride, influencing factors and risk to human health in the southwest plain of Shandong Province, North China.
This study investigated 324 groundwater samples collected from the southwest plain of Shandong Province during the dry and wet seasons. Groundwater fluoride in the study area and the influencing factors were characterized and discussed using statistical analysis, ion ratios, Piper diagrams, the saturation index (SI) and ArcGIS software. In addition, the risk posed by groundwater fluoride to human health was assessed. The results showed that groundwater in the study area had elevated fluoride concentrations, with average dry and wet season concentrations of 1.15 mg·L-1 and 1.08 mg·L-1, respectively. ...
Source: Ecotoxicology and Environmental Safety - December 3, 2020 Category: Environmental Health Authors: Liu J, Peng Y, Li C, Gao Z, Chen S Tags: Ecotoxicol Environ Saf Source Type: research

Response of periphytic biofilm in water to estrone exposure: Phenomenon and mechanism.
In this study, the changes in physiological activity and community composition of periphytic biofilms before and after E1 exposure were investigated. The results showed that periphytic biofilms exhibited high adaptability to E1 exposure at a concentration of 0.5 mg L-1 based on physiological results. The increase in productivity of extracellular polymeric substances (EPS) after exposure to E1 was the main factor preventing association between E1 and microbial cells. The increase in the activity of superoxide dismutase (SOD) and ATP enzyme activity and the change in the co-occurrence pattern of microbial communiti...
Source: Ecotoxicology and Environmental Safety - December 3, 2020 Category: Environmental Health Authors: Zhang F, Yu Y, Pan C, Saleem M, Wu Y Tags: Ecotoxicol Environ Saf Source Type: research

Production, functional stability, and effect of rhamnolipid biosurfactant from Klebsiella sp. on phenanthrene degradation in various medium systems.
Abstract The present study investigated the stability and efficacy of a biosurfactant produced by Klebsiella sp. KOD36 under extreme conditions and its potential for enhancing the solubilization and degradation of phenanthrene in various environmental matrices. Klebsiella sp. KOD36 produced a mono-rhamnolipids biosurfactant with a low critical micelle concentration (CMC) value. The biosurfactant was stable under extreme conditions (60 °C, pH 10 and 10% salinity) and could lower surface tension by 30% and maintained an emulsification index of> 40%. The emulsion index was also higher (17-43%) in the...
Source: Ecotoxicology and Environmental Safety - December 3, 2020 Category: Environmental Health Authors: Ahmad Z, Zhang X, Imran M, Zhong H, Andleeb S, Zulekha R, Liu G, Ahmad I, Coulon F Tags: Ecotoxicol Environ Saf Source Type: research

Methylmercury cytotoxicity and possible mechanisms in human trophoblastic HTR-8/SVneo cells.
In this study, MeHg cytotoxicity and its mechanisms in HTR-8/SVneo cells were investigated. MeHg inhibited HTR-8/SVneo cell viability and severely disrupted the cellular submicrostructure, showing a time-dose effect relationship. After MeHg treatment, the reactive oxygen species levels, malondialdehyde content, and superoxide dismutase (SOD) and catalase activities in the HTR-8/SVneo cells increased significantly with increased MeHg concentration (P
Source: Ecotoxicology and Environmental Safety - December 3, 2020 Category: Environmental Health Authors: Liao Y, Peng S, He L, Wang Y, Li Y, Ma D, Wang Y, Sun L, Zheng H, Yang W, Dai F, Zhao J Tags: Ecotoxicol Environ Saf Source Type: research

Occurrence and emission of phthalates, bisphenol A, and oestrogenic compounds in concentrated animal feeding operations in Southern China.
In this study, faeces, urine and food samples were collected from a typical livestock (cow) and a special livestock (pigeon) from concentrated animal feeding operations (CAFOs). The daily total oestrogen excretion of a single cow ranged from 192 μg/day to 671 μg/day, which was significantly higher than that of a single pigeon (0-0.01 μg/day). Conjugated oestrogens represented 22.0-46.0% of the total oestrogens excreted from cow faeces and 80.7-91.8% of those from cow urine, indicating that the form of the excreted oestrogens depends on the livestock species and type of excrement. BPA was all detecte...
Source: Ecotoxicology and Environmental Safety - December 3, 2020 Category: Environmental Health Authors: Tao HY, Zhang J, Shi J, Guo W, Liu X, Zhang M, Ge H, Li XY Tags: Ecotoxicol Environ Saf Source Type: research

Tetrachlorobisphenol A induced immunosuppression and uterine injury in mice.
Abstract Tetrachlorobisphenol A (TCBPA) is used as flame retardant, and it has been widely detected in the environmental and human samples. TCBPA is an endocrine disrupting chemical, but its effects on the immune system remains poorly understood. Here the effects of TCBPA on immune system were studied using combined in vivo and in vitro assays. Results showed that TCBPA could suppress the immune response in BALB/c mice via reducing the ratio of CD3+ T lymphocytes to regulatory T cells. Moreover, TCBPA exposure significantly induced the increasing secretion of four pro-inflammatory cytokines (IL-2, IL-12, IFN-&gamm...
Source: Ecotoxicology and Environmental Safety - December 3, 2020 Category: Environmental Health Authors: Wang Y, Zhang W, Li A, Song M Tags: Ecotoxicol Environ Saf Source Type: research

Associations between prenatal and postnatal lead exposure and preschool children humoral and cellular immune responses.
Abstract Studies have shown that lead exposure affected the immune function, but few studies have examined the relationships between in utero lead exposure, a sensitive period that is important for immune development, and later immune responses. To investigate the effects of prenatal and childhood lead exposure on the preschool-aged children's immune responses, a prospective birth cohort study was established in Wuhan, China, in which lead concentrations were analyzed in maternal urine during the third trimester and in plasma samples from children aged about 3 years. We assessed immune responses by measuring immun...
Source: Ecotoxicology and Environmental Safety - December 3, 2020 Category: Environmental Health Authors: Wang M, Xia W, Zeng Q, Zhang W, Qian X, Bao S, Zhou A, Li Y, Xu S Tags: Ecotoxicol Environ Saf Source Type: research

Evaluation of testicular structure in mice after exposure to environmentally relevant doses of manganese during critical windows of development.
This study suggests that Mn has the potential to alter the morphological parameters of the testes, affecting the spermatogenesis in mice. PMID: 33254399 [PubMed - in process] (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - December 3, 2020 Category: Environmental Health Authors: Souza TL, Batschauer AR, Brito PM, Martino-Andrade AJ, Ortolani-Machado CF Tags: Ecotoxicol Environ Saf Source Type: research

The efficiencies of inorganic mercury bio-methylation by aerobic bacteria under different oxygen concentrations.
In this study, two γ-proteobacteria strains (P. fluorescens TGR-B2 and P. putida TGR-B4) were obtained from the soil of The Three Gorges Reservoir (TGR), demonstrating effective aerobic transformation capacities of iHg into methylmercury (MeHg). Based on periodical changes in soil oxygen content of the TGR, a culture system was established, in which 300 ng Hg (II) L-1 and O2 were set at 7%, 14%, and 21%, respectively. Results indicated that the two strains differed significantly in bacterial growth rate and MeHg production. The kinetic model of MeHg showed typical characteristics of a "two-staged" proc...
Source: Ecotoxicology and Environmental Safety - December 3, 2020 Category: Environmental Health Authors: Cao D, Chen W, Xiang Y, Mi Q, Liu H, Feng P, Shen H, Zhang C, Wang Y, Wang D Tags: Ecotoxicol Environ Saf Source Type: research

Ammonia spatiotemporal distribution and risk assessment for freshwater species in aquatic ecosystem in China.
This study calculated the national aquatic life criteria for ammonia in China. The temporal and spatial distributions were investigated and the multi-tier ecological risks were assessed for ammonia and un-ionized ammonia (NH3) during 2014-2018 based on a total of 18989 ammonia monitoring data from 110 monitoring sites in seven river basins. The sensitivity comparison of different species taxa to ammonia showed that Perciformes fish should be listed as a priority protected species in the derivation of ammonia criteria. The participation of introduced aquaculture species have no significant impact on the final criteria value...
Source: Ecotoxicology and Environmental Safety - December 3, 2020 Category: Environmental Health Authors: Fan B, Li J, Wang X, Chen J, Gao X, Li W, Ai S, Cui L, Gao S, Liu Z Tags: Ecotoxicol Environ Saf Source Type: research

Response to: Quantifying the precision of ecological risk: Misunderstandings and errors in the methods for assessment factors versus species sensitivity distributions by Drs. Scott E. Belanger and Gregory J. Carr.
PMID: 33254402 [PubMed - in process] (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - December 3, 2020 Category: Environmental Health Authors: Kamo M, Sorgog K Tags: Ecotoxicol Environ Saf Source Type: research

Insights into uptake, accumulation, and subcellular distribution of selenium among eight wheat (Triticum aestivum L.) cultivars supplied with selenite and selenate.
ang D Abstract Selenium (Se)-enriched wheat can be improved by altering Se sources and selecting wheat cultivars. Such improvement can affect subcellular distribution and speciation of Se in wheat. Thus, a pot experiment was conducted to investigate Se uptake and distribution when Se was applied as selenite or selenate at low and high rates (1 and 10 mg kg-1, respectively). Moreover, Se's impact on the grain and biomass yield of eight wheat cultivars was also investigated. The subcellular distribution and speciation of Se were also explored to elucidate Se metabolism and micro-distribution pattern in whe...
Source: Ecotoxicology and Environmental Safety - December 3, 2020 Category: Environmental Health Authors: Wang M, Ali F, Qi M, Peng Q, Wang M, Bañuelos GS, Miao S, Li Z, Dinh QT, Liang D Tags: Ecotoxicol Environ Saf Source Type: research

The quality of dissolved organic matter extracted at different times from pig compost and its copper binding capacity based on EEM-PARAFAC.
The objective of the current study was set to explore the influence of different extraction time (i.e., 6, 12, and 24 h) on the composition, quality, and copper binding capacity of compost tea originated from pig manure compost. The results indicated that the extraction time obviously influenced the phenolic, aromatic carboxylic, and polycyclic aromatic groups of compost tea. In addition, the compost tea undergo the shorter extraction time (i.e., 6 and 12 h) contained more protein and humic-like compositions. Among the all treatments tested herein, the compost tea produced from 12 h extraction time obviously...
Source: Ecotoxicology and Environmental Safety - December 3, 2020 Category: Environmental Health Authors: Li X, Shi Z, Wang J, Jiang R Tags: Ecotoxicol Environ Saf Source Type: research

Removal of atrazine in catalytic degradation solutions by microalgae Chlorella sp. and evaluation of toxicity of degradation products via algal growth and photosynthetic activity.
Abstract Degradation solutions containing atrazine need to be further purified before they are discharged into the aquatic environment. With the objectives of evaluating removal capacity of the microalga Chlorella sp. toward atrazine in degradation solutions and toxicity of the degradation products, we investigated the removal efficiency (RE) and bioaccumulation of atrazine in the microalgae after an 8 d exposure to diluted degraded solutions containing 40 μg/L and 80 μg/L of atrazine as well as degradation products in the present study. Moreover, pure atrazine solutions with similar concentra...
Source: Ecotoxicology and Environmental Safety - December 3, 2020 Category: Environmental Health Authors: Hu N, Xu Y, Sun C, Zhu L, Sun S, Zhao Y, Hu C Tags: Ecotoxicol Environ Saf Source Type: research

The responses of the growth, cytochrome P450 isoenzymes activities and the metabolomics in earthworms to sublethal doses of dichlorvos in soil.
Abstract In this paper, earthworms (Eisenia fetida) were exposed to sublethal doses of dichlorvos (spiked concentration of 0.1, 1.0, 10 mg/kg) in soil for 14 days, the metabolomics and activities of cytochrome P450 (CYP) isoenzymes (CYP1A2, CYP2C9 and CYP3A4) of earthworms were analyzed aiming to identify sensitive biomarkers and reveal possible mode of toxic action. The results showed that CYP1A2 and CYP2C9 activity appeared to be more sensitive than CYP3A4 activity in response to dichlorvos, and that metabolic responses based on the metabolomics depended on both of the length of exposure and exposure dose. ...
Source: Ecotoxicology and Environmental Safety - December 3, 2020 Category: Environmental Health Authors: Yang X, Gong J, Zhang X, Zhang W, Li D, Lin J, Li X, Chai Y, Liu J Tags: Ecotoxicol Environ Saf Source Type: research

Deciphering the synergistic impact of elevated temperature and oil pollution on meiobenthic community structure: A benthocosm study.
Abstract Meiobenthos has been considered as an excellent tool for biomonitoring assessment. Elevated temperature and oil pollution are considered as the most pervasive aspects of global environmental changes and matter of concern for contemporary society. Presently, very limited information is available about the synergistic effect of these stressors on meiobenthic community structure and tolerance potential from tropical intertidal environment. Here, we assessed their impacts on meiobenthic community by conducting a 60 days long benthocosm experiment selecting three sets of temperature (25°, 30° and 35&nb...
Source: Ecotoxicology and Environmental Safety - December 3, 2020 Category: Environmental Health Authors: Ghosh M, Mandal S Tags: Ecotoxicol Environ Saf Source Type: research

Exogenous salicylic acid regulates cell wall polysaccharides synthesis and pectin methylation to reduce Cd accumulation of tomato.
In this study, all tomato seedlings were pre-treated with 100 μM SA for 3 d, then seedlings were used to analyze the role of SA in regulating plant cell wall resistance to Cd stress. The results showed that exogenous SA significantly reduced Cd accumulation in tomato plants and changed Cd distribution. By analyzing the cell wall composition, it was found cellulose, hemicellulose, pectin, and lignin were induced by SA. Interestingly, the content of Cd in pectin decreased by SA pretreatment, however it was increased in cellulose. Gene expression analysis showed SA up-regulated the expression level of lignin and cellu...
Source: Ecotoxicology and Environmental Safety - December 3, 2020 Category: Environmental Health Authors: Jia H, Wang X, Wei T, Wang M, Liu X, Hua L, Ren X, Guo J, Li J Tags: Ecotoxicol Environ Saf Source Type: research

Changes of sensitive microbial community in oil polluted soil in the coastal area in Shandong, China for ecorestoration.
Abstract Oil spills have an important threat to the ecological security and human health, for example the important oil field and coastal wetland Yellow River Delta is facing the dual problems of oil pollution and salinization. Therefore, the purpose of this study was to analyze the changes of soil microbial community and physicochemical properties, including pH value, total organic carbon (TOC), total petroleum hydrocarbons (TPHs) and electrical conductivity under the combined effect of petroleum and salinization. The soil properties results showed that the petroleum addition promoted the increase of TOC from 2.3...
Source: Ecotoxicology and Environmental Safety - December 3, 2020 Category: Environmental Health Authors: Shaoping K, Zhiwei D, Bingchen W, Huihui W, Jialiang L, Hongbo S Tags: Ecotoxicol Environ Saf Source Type: research

Chemical forms governing Cd tolerance and detoxification in duckweed (Landoltia punctata).
Abstract Duckweed (Landoltia punctata) is an ideal species to restore cadmium (Cd)-polluted waters due to its fast growth and easy harvesting. To understand its tolerance and detoxification mechanism, the Cd stress responses, subcellular Cd distribution and chemically bound Cd forms (especially protein-bound Cd) were surveyed in this study. L. punctata, a potential Cd bioremediation plant, was cultured hydroponically with Cd concentrations of 0.0, 0.5, 2.0, and 5.0 mg L-1 for 5 days. The results showed that the Cd content in L. punctata increased significantly as the Cd content increased. The majority of...
Source: Ecotoxicology and Environmental Safety - December 3, 2020 Category: Environmental Health Authors: Wang X, Zhang B, Wu D, Hu L, Huang T, Gao G, Huang S, Wu S Tags: Ecotoxicol Environ Saf Source Type: research

Toxicity assessment of total petroleum hydrocarbons in aquatic environments using the bioluminescent bacterium Aliivibrio fischeri.
This study addresses a rapid, sensitive and cost effective method for the detection of total petroleum hydrocarbons (TPHs) using Aliivibrio fischeri bioluminescence inhibition bioassay. At the first step, the optimum conditions including time, pH and temperature for growth of A. fischeri were determined. Then, two methods were used to evaluate the toxicity of petroleum compounds. In the first method, short-term (15 min) and long-term (16 h) toxicity assays were performed. In the second method luminescence kinetics of A. fischeri was investigated during 24 h. The results demonstrated the most appropriate time...
Source: Ecotoxicology and Environmental Safety - December 3, 2020 Category: Environmental Health Authors: Mirjani M, Soleimani M, Salari V Tags: Ecotoxicol Environ Saf Source Type: research

Characterization and spatial distribution of microplastics in two wild captured economic freshwater fish from north and west rivers of Guangdong province.
Abstract As a new type of pollutant, microplastics are of emerging widespread concern, while amount of research done in freshwater environments and organisms is litter compared to that in marine. Following this reality, the categories of MPs in two economic freshwater fish at 25 sites from 11 cities in the north and west rivers of Guangdong province were documented. Here, 76 individuals belong Oreochromis niloticus and Cirrhinus molitorella were investigated and microplastics were found in the GITs of 43.4% and gills of 25%. The average abundances of microplastics have significant difference between Oreochromis ni...
Source: Ecotoxicology and Environmental Safety - December 3, 2020 Category: Environmental Health Authors: Sun D, Wang J, Xie S, Tang H, Zhang C, Xu G, Zou J, Zhou A Tags: Ecotoxicol Environ Saf Source Type: research

Ameliorating effects of dietary Haematococcus pluvialis on arsenic-induced oxidative stress in rainbow trout (Oncorhynchus mykiss) fillet.
Abstract The current study was performed to investigate the protective effects of dietary Haematococcus pluvialis (H. pluvialis) on the oxidative stress induced by arsenic in rainbow trout (Oncorhynchus mykiss). The fish (20.70 ± 0.09 g) were fed with H. pluvialis at the levels of 0.28, 0.56, and 1.12 g 100 g-1 diet for 60 days. Then, each group was divided into two subgroups. In one of the subgroups, fish were exposed to arsenic challenge at a level of 9.1 mg/L. The other subset was used as the negative control. After the 96 h of toxicity test, protein and lipid oxidative...
Source: Ecotoxicology and Environmental Safety - December 3, 2020 Category: Environmental Health Authors: Milan FS, Maleki BRS, Moosavy MH, Mousavi S, Sheikhzadeh N, Khatibi SA Tags: Ecotoxicol Environ Saf Source Type: research