Major influencing factors identification and probabilistic health risk assessment of soil potentially toxic elements pollution in coal and metal mines across China: A systematic review
This study provides policymakers a quantitative foundation for developing differentiated strategies for sustainable remediation and risk-based management of PTEs in typical mining soils.PMID:38503102 | DOI:10.1016/j.ecoenv.2024.116231 (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - March 19, 2024 Category: Environmental Health Authors: Jingjing Yu Xiaoyang Liu Bin Yang Xiaodong Li Panpan Wang Bei Yuan Minghao Wang Tian Liang Pengfei Shi Renyou Li Hongguang Cheng Fasheng Li Source Type: research

Association of phthalate exposure with type 2 diabetes and the mediating effect of oxidative stress: A case-control and computational toxicology study
Ecotoxicol Environ Saf. 2024 Mar 18;274:116216. doi: 10.1016/j.ecoenv.2024.116216. Online ahead of print.ABSTRACTPhthalic acid esters (PAEs) are widely used as plasticizers and have been suggested to engender adverse effects on glucose metabolism. However, epidemiological data regarding the PAE mixture on type 2 diabetes (T2DM), as well as the mediating role of oxidative stress are scarce. This case-control study enrolled 206 T2DM cases and 206 matched controls in Guangdong Province, southern China. The concentrations of eleven phthalate metabolites (mPAEs) and the oxidative stress biomarker 8-hydroxy-2'-deoxyguanosine (8-...
Source: Ecotoxicology and Environmental Safety - March 19, 2024 Category: Environmental Health Authors: Yuxuan Tan Ziang Guo Huojie Yao Han Liu Yingyin Fu Yangxu Luo Rong He Yiwan Liu Pei Li Lihong Nie Lei Tan Chunxia Jing Source Type: research

Mechanisms of cadmium release from manganese-rich sediments driven by exogenous DOM and the role of microorganisms
This study linked DOM types to functional microbial communities, and explored the potential roles of different DOM types in Cd biotransformation in lake sediments.PMID:38503104 | DOI:10.1016/j.ecoenv.2024.116237 (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - March 19, 2024 Category: Environmental Health Authors: Changsheng Jin Zhongwu Li Mei Huang Xiang Ding Jia Chen Bolin Li Source Type: research

Global trends and burden of stroke attributable to particulate matter pollution from 1990 to 2019
CONCLUSIONS: Stroke attributed to PM2.5 is a global health problem, and the patterns and trends were heterogeneous across APMP and HAP. Targeted interventions should be formulated for APMP and HAP.PMID:38503105 | DOI:10.1016/j.ecoenv.2024.116205 (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - March 19, 2024 Category: Environmental Health Authors: Siqi Liu Yanming Lv Ya Zhang Huimin Suo Fan Wang Shuying Gao Source Type: research

Early-life exposure to PM2.5 leads to ASD-like phenotype in male offspring rats through activation of PI3K-AKT signaling pathway
This study suggests that early postnatal exposure to PM2.5 is more susceptible to ASD-like phenotype in offspring than maternal pregnancy exposure and the activation of PI3K-AKT signaling pathway may represent underlying mechanisms.PMID:38503106 | DOI:10.1016/j.ecoenv.2024.116222 (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - March 19, 2024 Category: Environmental Health Authors: Kang Li Xiaotian Liang Xiaohua Liu Yanpei Geng Jun Yan Lei Tian Huanliang Liu Wenqin Lai Yue Shi Zhuge Xi Bencheng Lin Source Type: research

Medium-term exposure to size-fractioned particulate matter and asthma exacerbations in China: A longitudinal study of asthmatics with poor medication adherence
CONCLUSION: This study suggests that medium-term exposure to PM is associated with an increased risk of asthma exacerbations in asthmatics with poor medication adherence, with a higher risk from smaller PM.PMID:38503107 | DOI:10.1016/j.ecoenv.2024.116234 (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - March 19, 2024 Category: Environmental Health Authors: Yufan Feng Wenyi Zhang Jing Wei Dingyuan Jiang Shilu Tong Cunrui Huang Zhiwei Xu Xiling Wang Junwen Tao Zhiwei Li Jihong Hu Yongming Zhang Jian Cheng Source Type: research

Dibutyl phthalate (DBP) promotes Epithelial-Mesenchymal Transition (EMT) to aggravate liver fibrosis into cirrhosis and portal hypertension (PHT) via ROS/TGF- β1/Snail-1 signalling pathway in adult rats
CONCLUSION: DBP could influence the progression of EMT through its toxicological effect by ROS/TGF-β1/Snail-1 signalling pathway, causing cirrhosis and PHT in final. The findings of this research might contribute to a novel comprehension of the underlying toxicological mechanisms and animal model involved in the progression of cirrhosis and PHT, and potentially offered a promising therapeutic target for the treatment of the disease.PMID:38503108 | DOI:10.1016/j.ecoenv.2024.116124 (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - March 19, 2024 Category: Environmental Health Authors: Min Chen Guang-Bo Wu Shan Hua Lei Zheng Qiang Fan Meng Luo Source Type: research

Corrigendum to 'Concentrations, leachability, and health risks of mercury in green tea from major production areas in China' Ecotoxicol. Environ. Saf. 232 (2022) 113279
Ecotoxicol Environ Saf. 2024 Mar 18;274:116233. doi: 10.1016/j.ecoenv.2024.116233. Online ahead of print.NO ABSTRACTPMID:38503109 | DOI:10.1016/j.ecoenv.2024.116233 (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - March 19, 2024 Category: Environmental Health Authors: Qingfeng Wang Dan Wang Zhonggen Li Yuyu Wang Yan Yang Mengxun Liu Dadong Li Guangyi Sun Boping Zeng Source Type: research

Bioaccumulation of molybdate ions by alkanotrophic Rhodococcus leads to significant alterations in cellular ultrastructure and physiology
Ecotoxicol Environ Saf. 2024 Mar 18;274:116190. doi: 10.1016/j.ecoenv.2024.116190. Online ahead of print.ABSTRACTAlkanotrophic Rhodococcus strains from the Regional Specialised Collection of Alkanotrophic Microorganisms (acronym IEGM, www.iegmcol.ru) were screened for accumulation and sorption of MoO42- ions. Morphological and ultrastructural changes observed in bacterial cells during their cultivation in the molybdenum-containing medium are described. The species peculiarities, growth substrate preferences, and other physiological features allowing for the efficient removal of molybdate ions from the culture medium are di...
Source: Ecotoxicology and Environmental Safety - March 19, 2024 Category: Environmental Health Authors: Irina B Ivshina Maria S Kuyukina Lyudmila V Litvinenko Anastasia A Golysheva Nadezhda A Kostrikina Vladimir V Sorokin Andrey L Mulyukin Source Type: research

Lycium barbarum polysaccharide's protective effects against PM < sub > 2.5 < /sub > -induced cellular senescence in HUVECs
In this study, we investigated the impact of PM2.5 exposure on vascular endothelial senescence and explored the intervention effects of LBP in human umbilical vein endothelial cells (HUVECs). We found that PM2.5 exposure dose-dependently reduced cell viability and proliferation in HUVECs while increasing the production of reactive oxygen species (ROS), malondialdehyde (MDA), and hydrogen peroxide (H2O2). Additionally, PM2.5 exposure inhibited the activity of superoxide dismutase (SOD). Notably, PM2.5 exposure induced autophagy impairments and cellular senescence. However, LBP mitigated PM2.5-induced cell damage. Further st...
Source: Ecotoxicology and Environmental Safety - March 17, 2024 Category: Environmental Health Authors: Haochong Shen Meidi Gong Juan Hu Qing Yan Minghao Zhang Rao Zheng Jing Wu Yi Cao Source Type: research

What do we know about dermal bioaccessibility of metals coated on antibacterial films?
This study reports on the important features that must be considered when assessing the bioaccessibility of Ag, Cu, and Zn in antibacterial films. Specifically, the effects of the artificial sweat component (i.e., amino acid and pH), surface weathering of antibacterial films, wipe sampling, and sebum were carefully examined. Our findings suggest that amino acids greatly affect bioaccessibility as amino acids act as ligands to facilitate metal ion leaching. In addition, constant exposure to ultraviolet C causes the film surface to oxidize, which significantly increases metal bioaccessibility due to the electrostatic repulsi...
Source: Ecotoxicology and Environmental Safety - March 17, 2024 Category: Environmental Health Authors: Seon-Woo Kwon Junyoung Park Dong-Jun Baek Haeun Kim Suk Soon Choi Jung-Hwan Kwon Jinsung An Source Type: research

Mechanistic insight into human androgen receptor-mediated endocrine disrupting potential of cyclic depsipeptide mycotoxin, beauvericin, and influencing environmental factors for its biosynthesis in Fusarium oxysporum KFCC 11363P on rice cereal
Ecotoxicol Environ Saf. 2024 Mar 16;274:116227. doi: 10.1016/j.ecoenv.2024.116227. Online ahead of print.ABSTRACTIn current study, Fusarium mycotoxin, beauvericin (BEA), has endocrine disrupting potential through suppressing the exogenous androgen receptor (AR)-mediated transcriptional activation. BEA was classified as an AR antagonist, with IC30 and IC50 values indicating that it suppressed AR dimerization in the cytosol. BEA suppress the translocation of cytosolic activated ARs to the nucleus via exogenous androgens. Furthermore, we investigated the impact of environmental conditions for BEA production on rice cereal usi...
Source: Ecotoxicology and Environmental Safety - March 17, 2024 Category: Environmental Health Authors: Da-Hyun Jeong Da-Woon Jung Chaemin You Hee-Seok Lee Source Type: research

Environmental-related doses of afidopyropen induced toxicity effects in earthworms (Eisenia fetida)
Ecotoxicol Environ Saf. 2024 Mar 16;274:116223. doi: 10.1016/j.ecoenv.2024.116223. Online ahead of print.ABSTRACTAfidopyropen has high activity against pests. However, it poses potential risks to the soil ecology after entering the environment. The toxicity of afidopyropen to earthworms (Eisenia fetida) was studied for the first time in this study. The results showed that afidopyropen had low level of acute toxicity to E. fetida. Under the stimulation of chronic toxicity, the increase of reactive oxygen species (ROS) level activated the antioxidant and detoxification system, which led to the increase of superoxide dismutas...
Source: Ecotoxicology and Environmental Safety - March 17, 2024 Category: Environmental Health Authors: Tao Yin Jingru Zhang Chang Liu Yannan Xue Zhenlong Liu Shuang Liu Longzhi Guo Jinhua Wang Xiaoming Xia Source Type: research

Lycium barbarum polysaccharide's protective effects against PM < sub > 2.5 < /sub > -induced cellular senescence in HUVECs
In this study, we investigated the impact of PM2.5 exposure on vascular endothelial senescence and explored the intervention effects of LBP in human umbilical vein endothelial cells (HUVECs). We found that PM2.5 exposure dose-dependently reduced cell viability and proliferation in HUVECs while increasing the production of reactive oxygen species (ROS), malondialdehyde (MDA), and hydrogen peroxide (H2O2). Additionally, PM2.5 exposure inhibited the activity of superoxide dismutase (SOD). Notably, PM2.5 exposure induced autophagy impairments and cellular senescence. However, LBP mitigated PM2.5-induced cell damage. Further st...
Source: Ecotoxicology and Environmental Safety - March 17, 2024 Category: Environmental Health Authors: Haochong Shen Meidi Gong Juan Hu Qing Yan Minghao Zhang Rao Zheng Jing Wu Yi Cao Source Type: research

What do we know about dermal bioaccessibility of metals coated on antibacterial films?
This study reports on the important features that must be considered when assessing the bioaccessibility of Ag, Cu, and Zn in antibacterial films. Specifically, the effects of the artificial sweat component (i.e., amino acid and pH), surface weathering of antibacterial films, wipe sampling, and sebum were carefully examined. Our findings suggest that amino acids greatly affect bioaccessibility as amino acids act as ligands to facilitate metal ion leaching. In addition, constant exposure to ultraviolet C causes the film surface to oxidize, which significantly increases metal bioaccessibility due to the electrostatic repulsi...
Source: Ecotoxicology and Environmental Safety - March 17, 2024 Category: Environmental Health Authors: Seon-Woo Kwon Junyoung Park Dong-Jun Baek Haeun Kim Suk Soon Choi Jung-Hwan Kwon Jinsung An Source Type: research