Ecotoxicology and Environmental Safety This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Nano-CeO 2 activates physical and chemical defenses of garlic (Allium sativum L.) for reducing antibiotic resistance genes in plant endosphere
Ecotoxicol Environ Saf. 2024 Apr 2:116289. doi: 10.1016/j.ecoenv.2024.116289. Online ahead of print.ABSTRACTThe transmission of manure- and wastewater-borne antibiotic-resistant bacteria (ARB) to plants contributes to the proliferation of antimicrobial resistance in agriculture, necessitating effective strategies for preventing the spread of antibiotic resistance genes (ARGs) from ARB in the environment to humans. Nanomaterials are potential candidates for efficiently controlling the dissemination of ARGs. The present study investigated the abundance of ARGs in hydroponically grown garlic (Allium sativum L.) following nano...
Source: Ecotoxicology and Environmental Safety - April 3, 2024 Category: Environmental Health Authors: Yinuo Xu Mengna Tao Wei Xu Lanqing Xu Le Yue Xuesong Cao Feiran Chen Zhenyu Wang Source Type: research

Effects of cadmium and zinc interactions on the physiological biochemistry and enrichment characteristics of Iris pseudacorus
In this study, the effects of single and combined Cd and Zn stress on I. pseudacorus growth and the enrichment of heavy metals in I. pseudacorus seedlings were investigated. The results showed that under Cd (160 μM) and Zn (800 μM) stress, plant growth was significantly inhibited and photosynthetic performance was affected. Cd+Zn200 (160 μM + 200 μM) reduced the levels of malondialdehyde, hydrogen peroxide, and non-protein thiols by 31.29%, 53.20%, and 13.29%, respectively, in the aboveground tissues compared with levels in the single Cd treatment. However, Cd+Zn800 (160 μM + 800 μM) had no effect. Cd and Zn800 inhib...
Source: Ecotoxicology and Environmental Safety - April 2, 2024 Category: Environmental Health Authors: Xiaofang Yu Yujia Liu Linjie Yue Xiaoxuan Zeng Yuwei Huang Hanyue Xue Bin Xu Junrui Zhang Xue Xiao Lijuan Yang Ting Lei Mingyan Jiang Beibei Jiang Suping Gao Xi Li Source Type: research

Nod-like receptor protein 3 inflammasome-mediated pyroptosis contributes to chronic NaAsO 2 exposure-induced fibrotic changes and dysfunction in the liver of SD rats
In this study, we administered varying doses of sodium arsenite (NaAsO2) and 10 mg/kg.bw MCC950 (a particular tiny molecular inhibitor targeting NLRP3) to Sprague-Dawley (SD) rats for 36 weeks to explore the involvement of NLRP3 inflammasome in NaAsO2-induced liver injury. The findings suggested that prolonged exposure to NaAsO2 resulted in pyroptosis in liver tissue of SD rats, accompanied by the fibrotic injury, extracellular matrix (ECM) deposition and liver dysfunction. Moreover, long-term NaAsO2 exposure activated NLRP3 inflammasome, leading to the release of pro-inflammatory cytokines in liver tissue. After treatment...
Source: Ecotoxicology and Environmental Safety - April 2, 2024 Category: Environmental Health Authors: Ying Jin Qian Song Rui He Heng Diao Huijie Gaoyang Lei Wang Lili Fan Dapeng Wang Source Type: research

Integrated network toxicology, molecular docking, and in vivo experiments to elucidate molecular mechanism of aflatoxin B1 hepatotoxicity
Ecotoxicol Environ Saf. 2024 Apr 1;275:116278. doi: 10.1016/j.ecoenv.2024.116278. Online ahead of print.ABSTRACTDue to the rise in temperature and sea level caused by climate change, the detection rate of aflatoxin B1 (AFB1) in food crops has increased dramatically, and the frequency and severity of aflatoxicosis in humans and animals are also increasing. AFB1 has strong hepatotoxicity, causing severe liver damage and even cancer. However, the mechanism of AFB1 hepatotoxicity remains unclear. By integrating network toxicology, molecular docking and in vivo experiments, this research was designed to explore the potential he...
Source: Ecotoxicology and Environmental Safety - April 2, 2024 Category: Environmental Health Authors: Bingjie Ge Kexin Yan Rui Sang Wei Wang Xinman Liu Minghong Yu Xiaotong Liu Qian Qiu Xuemei Zhang Source Type: research

Ambient air pollution exposure and the risk of probable sarcopenia: A prospective cohort study
CONCLUSIONS: Air pollution exposure elevated the risk of developing sarcopenia and related manifestations in a dose-dependent manner, while physical activity maintained protective under this circumstance. Efforts should be made to control air pollution and emphasize the importance of physical activity for skeletal muscle health under this circumstance.PMID:38564861 | DOI:10.1016/j.ecoenv.2024.116273 (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - April 2, 2024 Category: Environmental Health Authors: Lubing Cai Jiale Tan Xinyi Chen Fuchao Wang Xingyu Zhang Jiwu Chen Cong Liu Yaying Sun Source Type: research

Associations of glyphosate exposure and serum sex steroid hormones among 6-19-year-old children and adolescents
Ecotoxicol Environ Saf. 2024 Apr 1;275:116266. doi: 10.1016/j.ecoenv.2024.116266. Online ahead of print.ABSTRACTGlyphosate, ranked as one of the most widely used herbicides in the world, has raised concerns about its potential disruptive effects on sex hormones. However, limited human evidence was available, especially for children and adolescents. The present study aimed to examine the associations between exposure to glyphosate and sex hormones among participants aged 6-19 years, utilizing data from the National Health and Nutrition Examination Survey (NHANES) conducted between 2013 and 2016. Children and adolescents who...
Source: Ecotoxicology and Environmental Safety - April 2, 2024 Category: Environmental Health Authors: Xiaojie Sun Huan Zhang Xiaojing Huang Di Yang Chuansha Wu Hongxiu Liu Ling Zhang Source Type: research

Corrigendum to 'Paracrine signaling of ferroptotic airway epithelium in crystalline silica-induced pulmonary fibrosis augments local fibroblast activation through glycolysis reprogramming' [Ecotoxicol. Environ. Saf. (2024) 271]
Ecotoxicol Environ Saf. 2024 Apr 1;275:116267. doi: 10.1016/j.ecoenv.2024.116267. Online ahead of print.NO ABSTRACTPMID:38564863 | DOI:10.1016/j.ecoenv.2024.116267 (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - April 2, 2024 Category: Environmental Health Authors: Qianmin Li Yi Ling Yu Ma Tao Zhang Youjing Yang Shasha Tao Source Type: research

Bioinformatics-based dynamics of cuproptosis -related indicators in experimental silicosis
Ecotoxicol Environ Saf. 2024 Apr 1;275:116286. doi: 10.1016/j.ecoenv.2024.116286. Online ahead of print.ABSTRACTPneumoconiosis is one of the most serious occupational diseases worldwide. Silicosis due to prolonged inhalation of free silica dust during occupational activities is one of the main types. Cuproptosis is a newly discovered mode of programmed cell death characterized by the accumulation of free copper in the cell, which ultimately leads to cell death. Increased copper in the serum of silicosis patients, suggests that the development of silicosis is accompanied by changes in copper metabolism, but whether cupropto...
Source: Ecotoxicology and Environmental Safety - April 2, 2024 Category: Environmental Health Authors: Jiarui Xia Chenchen Wu Xiaofei Jin Mingcui Ding Chengpeng Zhang Guangjie Hou Changfu Hao Wu Yao Source Type: research

Multiple dietary patterns and the association between long-term air pollution exposure with type 2 diabetes risk: Findings from UK Biobank cohort study
CONCLUSIONS: Multiple forms of healthy DPs help reduce the T2D risk associated with long-term exposure to NO2 and NOX. Our findings indicate that adherence to healthy DPs is a feasible T2D prevention strategy for people long-term suffering from NO2 and NOX pollution.PMID:38564865 | DOI:10.1016/j.ecoenv.2024.116274 (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - April 2, 2024 Category: Environmental Health Authors: Chaonan Fan Wenjuan Wang Shanze Wang Wensu Zhou Li Ling Source Type: research

Aldicarb disturbed bile acid, steroid hormone and oxylipin homeostasis in C57BL/6  J mice
Ecotoxicol Environ Saf. 2024 Apr 1;275:116285. doi: 10.1016/j.ecoenv.2024.116285. Online ahead of print.ABSTRACTMounting evidence has shown that the gut microbiota plays a key role in human health. The homeostasis of the gut microbiota could be affected by many factors, including environmental chemicals. Aldicarb is a carbamate insecticide used to control a variety of insects and nematode pests in agriculture. Aldicarb is highly toxic and its wide existence has become a global public health concern. In our previous study, we have demonstrated that aldicarb disturbed the gut microbial community structure and composition. Ho...
Source: Ecotoxicology and Environmental Safety - April 2, 2024 Category: Environmental Health Authors: Xin Liu Pengcheng Tu Ying Zhang Weichen Xu Jinjun Shan Bei Gao Source Type: research

Leucine improves thiram-induced tibial dyschondroplasia and gut microbiota dysbiosis in broilers
In this study, we aimed to investigate the mechanism of action of leucine in mitigating thiram-induced TD and leucine effects on gut microbial diversity. Broiler chickens were randomly divided into five equal groups: control group (standard diet), thiram-induced group (thiram 80 mg/kg from day 3 to day 7), and different concentrations of leucine groups (0.3%, 0.6%, 0.9% leucine from day 8 to day 18). Performance indicator analysis and tibial parameter analysis showed that leucine positively affected thiram-induced TD broilers. Additionally, mRNA expressions and protein levels of HIF-1α/VEGFA and Ihh/PTHrP genes were deter...
Source: Ecotoxicology and Environmental Safety - April 2, 2024 Category: Environmental Health Authors: Shimeng Zhou Chuxian Quan Zhao Zhang Saisai Gong Shah Nawaz Yan Zhang Muhammad Fakhar-E-Alam Kulyar Quan Mo Jiakui Li Source Type: research

Inadvertent antibiotic exposure during pregnancy may increase the risk for neural tube defects in offspring
CONCLUSIONS: Intentional antibiotic use during early pregnancy may not be associated with NTDs, while IAE during pregnancy is associated with higher NTD risk in offspring. Macrolides are crucial risk factors. Milk, and river, well, or pond water may be important sources of IAE.PMID:38564868 | DOI:10.1016/j.ecoenv.2024.116271 (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - April 2, 2024 Category: Environmental Health Authors: Qianhui Cheng Yongyan Chen Jufen Liu Lei Jin Zhiwen Li Aiguo Ren Linlin Wang Source Type: research

Nicotinamide mononucleotide maintains cytoskeletal stability and fortifies mitochondrial function to mitigate oocyte damage induced by Triocresyl phosphate
In this study, we employed an in vitro model for the first time to investigate the effects of TOCP on the maturation process of mouse oocytes. TOCP exposure hampered the meiotic division process, as evidenced by a reduction in the extrusion of the first polar body from oocytes. Subsequent research revealed the disruption of the oocyte cell cytoskeleton induced by TOCP, resulting in abnormalities in spindle organization, chromosome alignment, and actin filament distribution. This disturbance further extended to the rearrangement of organelles within oocytes, particularly affecting the mitochondria. Importantly, after TOCP t...
Source: Ecotoxicology and Environmental Safety - April 2, 2024 Category: Environmental Health Authors: Fei Meng Yanan Zhang Jingyi Du Naigang Li Xinghui Qiao Yuan Yao Tiantian Zhao Dong Wu Fan Peng Dongshuang Wang Shuang Yang Jiaming Shi Ruoxi Liu Wenjuan Zhou Aijun Hao Source Type: research

Symplasmic and transmembrane zinc transport is modulated by cadmium in the Cd/Zn hyperaccumulator Sedum alfredii
This study investigated the influence of Cd (25 µM) on Zn accumulation in a hyperaccumulating (HE) and a non-hyperaccumulating (NHE) ecotype of Sedum alfredii Hance at short-term supply of replete (Zn5, 5 µM) and excess (Zn400, 400 µM) Zn. Cd inhibited Zn accumulation in both ecotypes, especially under Zn400, in organs with active metal sequestration, i.e. roots of NHE and shoots of HE. Direct biochemical Cd/Zn competition at the metal-protein interaction and changes in transporter gene expression contributed to the observed accumulation patterns in the roots. Specifically, in HE, Cd stimulated SaZIP4 and SaPCR2 under Z...
Source: Ecotoxicology and Environmental Safety - April 2, 2024 Category: Environmental Health Authors: Ke Cao Noelia Jaime-P érez Ana Mijovilovich Filis Morina Syed Nadeem Hussain Bokhari Yunqi Liu Hendrik K üpper Qi Tao Source Type: research

Causal effects of PM 2.5 exposure on neuropsychiatric disorders and the mediation via gut microbiota: A Mendelian randomization study
CONCLUSIONS: This study suggested that exposure to PM2.5 would increase the risk of neuropsychiatric disorders, partially by influencing the profile of gut microbiota. Comprehensive regulations on air pollutants are needed to help prevent neuropsychiatric disorders.PMID:38564871 | DOI:10.1016/j.ecoenv.2024.116257 (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - April 2, 2024 Category: Environmental Health Authors: Chanhua Li Hao Chen Ye Gu Wanling Chen Meiliang Liu Qinggui Lei Yujun Li Xiaomei Liang Binyuan Wei Dongping Huang Shun Liu Li Su Xiaoyun Zeng Lijun Wang Source Type: research