Ecotoxicology and Environmental Safety This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Physiology and molecular basis of thallium toxicity and accumulation in Arabidopsis thaliana
Ecotoxicol Environ Saf. 2024 Apr 9;276:116290. doi: 10.1016/j.ecoenv.2024.116290. Online ahead of print.ABSTRACTThallium (Tl) is a non-essential metal mobilized through industrial processes which can lead to it entering the environment and exerting toxic effects. Plants are fundamental components of all ecosystems. Therefore, understanding the impact of Tl on plant growth and development is of great importance for assessing the potential environmental risks of Tl. Here, the responses of Arabidopsis thaliana to Tl were elucidated using physiological, genetic, and transcriptome analyses. Thallium can be absorbed by plant roo...
Source: Ecotoxicology and Environmental Safety - April 10, 2024 Category: Environmental Health Authors: Hsin-Fang Chang Shao-Chin Tseng Mau-Tsu Tang Silver Sung-Yun Hsiao Der-Chuen Lee Shan-Li Wang Kuo-Chen Yeh Source Type: research

Using oral bioaccessibility measurements to refine risk assessment of potentially toxic elements in topsoils across an urban area
This study considers how PTE bioaccessibility in soils varies spatially across urban areas and refines human health risk assessment for these PTEs using site specific oral bioaccessibility results to present the first regional assessment of risk that incorporates bioaccessibility testing. A total of 103 urban soil samples were selected for UBM testing. Results showed low bioaccessible fraction (BAF) for the PTEs from geogenic sources: Cr (0.45-5.9%), Ni (1.1-46.3%) and V (2.2-23.9%). Higher BAF values were registered for PTEs from anthropogenic sources: As (8.0-86.9%), Cu (3.4-67.8%), Pb (9.1-106.2%) and Zn (2.4-77.5%). Gr...
Source: Ecotoxicology and Environmental Safety - April 10, 2024 Category: Environmental Health Authors: Tatiana Cocerva Matthew Robb Ada Wong Rory Doherty Jennifer Newell Ulrich Ofterdinger Manus Carey Mark Cave Siobhan F Cox Source Type: research

Biomass fuels related-PM < sub > 2.5 < /sub > promotes lung fibroblast-myofibroblast transition through PI3K/AKT/TRPC1 pathway
In this study, we aimed to investigate the implication and regulatory effect of biomass fuels related-PM2.5 (BRPM2.5) concerning the pathological process of fibroblast-to-myofibroblast transition (FMT) in the context of COPD. In vivo experimentation revealed that exposure to biofuel smoke was associated with airway inflammation in rats. After 4 weeks of exposure, there was inflammation in the small airways, but no significant structural changes in the airway walls. However, after 24 weeks, airway remodeling occurred due to increased collagen deposition, myofibroblast proliferation, and tracheal wall thickness. In vitro, ce...
Source: Ecotoxicology and Environmental Safety - April 10, 2024 Category: Environmental Health Authors: Shuni Li Lihui Qu Lifen Zhou Na Zhan Linmei Liu Yuquan Ling Qingzi Chen Wuping Lai Nan Lin Jianhua Li Source Type: research

GPR39-mediated ERK1/2 signaling reduces permethrin-induced proliferation of estrogen receptor α-negative cells
The objective of this study was to determine the impact of the pyrethroid insecticide permethrin on the growth of estrogen receptor negative breast cancer cells MDA-MB-231. Using tandem mass spectrometric techniques, the effect of permethrin on cellular protein expression was investigated, and gene ontology and pathway function enrichment analyses were performed on the deregulated proteins. Finally, molecular docking simulations of permethrin with the candidate target protein was performed and the functionality of the protein was confirmed through gene knockdown experiments. Our findings demonstrate that exposure to 10-40 ...
Source: Ecotoxicology and Environmental Safety - April 10, 2024 Category: Environmental Health Authors: Ming-Hui Shi Yi Yan Xi Niu Jia-Fu Wang Sheng Li Source Type: research

Human health risks of heavy metal(loid)s mediated through crop ingestion in a coal mining area in Eastern China
Ecotoxicol Environ Saf. 2024 Apr 9;276:116305. doi: 10.1016/j.ecoenv.2024.116305. Online ahead of print.ABSTRACTThe heavy metal(loid)s (HMs) in soils can be accumulated by crops grown, which is accompanied by crop ingestion into the human body and then causes harm to human health. Hence, the health risks posed by HMs in three crops for different populations were assessed using Health risk assessment (HRA) model coupled with Monte Carlo simulation. Results revealed that Zn had the highest concentration among three crops; while Ni was the main polluting element in maize and soybean, and As in rice. Non-carcinogenic risk for ...
Source: Ecotoxicology and Environmental Safety - April 10, 2024 Category: Environmental Health Authors: Menglu Zhao Huijuan Wang Jiaxun Sun Boya Cai Rui Tang Xiaoyong Song Xinmiao Huang Yafeng Liu Zhengqiu Fan Source Type: research

Molecular strategies of the pygmy grasshopper Eucriotettix oculatus adapting to long-term heavy metal pollution
Ecotoxicol Environ Saf. 2024 Apr 9;276:116301. doi: 10.1016/j.ecoenv.2024.116301. Online ahead of print.ABSTRACTTo study the heavy metal accumulation and its impact on insect exterior and chromosome morphology, and reveal the molecular mechanism of insects adapting to long-term heavy metal compound pollution habitats, this study, in the Diaojiang river basin, which has been polluted by heavy metals(HMs) for nearly a thousand years, two Eucriotettix oculatus populations was collected from mining and non-mining areas. It was found that the contents of 7 heavy metals (As, Cd, Pb, Zn, Cu, Sn, Sb) in E. oculatus of the mining a...
Source: Ecotoxicology and Environmental Safety - April 10, 2024 Category: Environmental Health Authors: Xiao-Dong Li Guo-Fang Jiang Ran Li Yi Bai Guo-Song Zhang Shu-Juan Xu Wei-An Deng Source Type: research

Effects of different sizes of ambient particulate matter and household fuel use on physical function: National cohort study in China
CONCLUSION: This study underscores the singular and combined detrimental effects of air pollutants and solid fuel usage on physical function. Addressing fine particulate matter, specifically PM1, and prioritizing efforts to improve household fuel cleanliness in regions with elevated air pollution levels are crucial for preventing physical disability.PMID:38593496 | DOI:10.1016/j.ecoenv.2024.116308 (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - April 9, 2024 Category: Environmental Health Authors: Haochen Wang Pengsen Mou Yuxin Yao Jianbang Su Jiaxin Guan Ze Zhao Jing Dong Yingliang Wei Source Type: research

Elucidating the intricacies of the H < sub > 2 < /sub > S signaling pathway in gasotransmitters: Highlighting the regulation of plant thiocyanate detoxification pathways
Ecotoxicol Environ Saf. 2024 Apr 8;276:116307. doi: 10.1016/j.ecoenv.2024.116307. Online ahead of print.ABSTRACTIn recent decades, there has been increasing interest in elucidating the role of sulfur-containing compounds in plant metabolism, particularly emphasizing their function as signaling molecules. Among these, thiocyanate (SCN-), a compound imbued with sulfur and nitrogen, has emerged as a significant environmental contaminant frequently detected in irrigation water. This compound is known for its potential to adversely impact plant growth and agricultural yield. Although adopting exogenous SCN- as a nitrogen source...
Source: Ecotoxicology and Environmental Safety - April 9, 2024 Category: Environmental Health Authors: Yu-Xi Feng Peng Tian Cheng-Zhi Li Xiao-Dong Hu Yu-Juan Lin Source Type: research

Combined toxic effects of polyethylene microplastics and lambda-cyhalothrin on gut of zebrafish (Danio rerio)
This study sought to assess the adsorption of lambda-cyhalothrin (LCT) by virgin and aged polyethylene MPs (VPE and APE, respectively), and to examine their influence on LCT's toxicity in zebrafish, specifically regarding acute toxicity, oxidative stress, gut microbiota and immunity. The adsorption results showed that VPE and APE could adsorb LCT, with adsorption capacities of 34.4 mg∙g-1 and 39.0 mg∙g-1, respectively. Compared with LCT exposure alone, VPE and APE increased the acute toxicity of LCT to zebrafish. Additionally, exposure to LCT and PE-MPs alone can induce oxidative stress in the zebrafish gut, while comb...
Source: Ecotoxicology and Environmental Safety - April 9, 2024 Category: Environmental Health Authors: Yuexing Zhao Haiyue Chen Hongwu Liang Tingting Zhao Bo Ren Yanhong Li Hanlin Liang Yu Liu Huihui Cao Naqi Cui Wei Wei Source Type: research