Construction of Tetrahymena strains with highly active arsenic methyltransferase genes for arsenic detoxification in aquatic environments
This study compared arsenic tolerance, accumulation, methylation, and efflux in 11 Tetrahymena species. Nineteen arsenite (As(III)) S-adenosylmethionine (SAM) methyltransferase (arsM) genes, of which 12 are new discoveries, were identified, and protein sequences were studied. We then constructed recombinant cell lines based on the Tetrahymena thermophila (T. thermophila) wild-type SB210 strain and expressed each of the 19 arsM genes under the control of the metal-responsive the MTT1 promoter. In the presence of Cd2+ and As(V), expression of the arsM genes in the recombinant cell lines was much higher than in the donor spec...
Source: Ecotoxicology and Environmental Safety - March 28, 2024 Category: Environmental Health Authors: Wenjun Xiong Wei Wei Man He Bin Hu Jun Men Jiawei Tu Wei Miao Source Type: research

Interference of two typical polycyclic aromatic hydrocarbons on the induced anti-grazing defense of Tetradesmus obliquus
This study examined the effects of two typical PAHs, phenanthrene (Phe) and naphthalene (Nap), on the anti-grazing defense mechanisms of Tetradesmus obliquus, a primary producer in freshwater food chains. Four non-lethal concentrations (0.01, 0.1, 1, and 10 mg L-1) of Phe and Nap were tested and the population growth, photosynthetic capacity, pigment content, and morphological defense of T. obliquus were analyzed. The results indicated that Phe and Nap inhibited both the growth rate and formation of defensive colonies of T. obliquus induced by Daphnia grazing cues, and the inhibition ratio increased with concentration. Phe...
Source: Ecotoxicology and Environmental Safety - March 28, 2024 Category: Environmental Health Authors: Yueqiang Pan Xuanhe Jia Ruowen Ding Siyu Xia Xuexia Zhu Source Type: research

Tailoring functional two-dimensional nanohybrids: A comprehensive approach for enhancing photocatalytic remediation
Ecotoxicol Environ Saf. 2024 Mar 27;275:116221. doi: 10.1016/j.ecoenv.2024.116221. Online ahead of print.ABSTRACTPhotocatalysis is gaining prominence as a viable alternative to conventional biohazard treatment technologies. Two-dimensional (2D) nanomaterials have become crucial for fabricating novel photocatalysts due to their nanosheet architectures, large surface areas, and remarkable physicochemical properties. Furthermore, a variety of applications are possible with 2D nanomaterials, either in combination with other functional nanoparticles or by utilizing their inherent properties. Henceforth, the review commences its...
Source: Ecotoxicology and Environmental Safety - March 28, 2024 Category: Environmental Health Authors: Vimala Rathinam Thiruppathi Venkadajapathy Sivarmakrishnan Sivaperumal Source Type: research

In vivo chronic exposure to inorganic mercury worsens hypercholesterolemia, oxidative stress and atherosclerosis in the LDL receptor knockout mice
In conclusion, in vivo chronic exposure to Hg worsens the hypercholesterolemia, impairs mitochondrial bioenergetics and redox function, alters immune cells profile and function, causes several tissues oxidative damage and accelerates atherosclerosis development.PMID:38547729 | DOI:10.1016/j.ecoenv.2024.116254 (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - March 28, 2024 Category: Environmental Health Authors: Maiara I C Queiroz Carolina M Lazaro Lohanna M B Dos Santos Thiago Rentz Jo ão V Virgilio-da-Silva Pedro M M Moraes-Vieira Francisco A S Cunha Josu é C C Santos Anibal E Vercesi Ana Catarina R Leite Helena C F Oliveira Source Type: research

Ultrafast and highly efficient Cd(II) and Pb(II) removal by magnetic adsorbents derived from gypsum and corncob: Performances and mechanisms
In this study, through co-pyrolysis with corncob waste, titanium gypsum (TiG) was transformed into magnetic adsorbents (GCx, where x denotes the proportion of corncob in the gypsum-corncob mixture) for the removal of Cd(II) and Pb(II). GC10, the optimal adsorbent, which was composed primarily of anhydrite, calcium sulfide, and magnetic Fe3O4, exhibited significantly faster adsorption kinetics (rate constant k1 was 218 times and 9 times of raw TiG for Cd(II) and Pb(II)) and higher adsorption capacity (Qe exceeded 200 mg/g for Cd(II) and 400 mg/g for Pb(II)) than raw TiG and previous adsorbents. Cd(II) removal was more profo...
Source: Ecotoxicology and Environmental Safety - March 28, 2024 Category: Environmental Health Authors: Yuhong Yang Tongtong Han Jing Wang Source Type: research

Phthalate exposure aggravates periodontitis by activating NF κB pathway
CONCLUSION: Exposure to multiple phthalates was positively associated with periodontitis in US adults between 30 and 80 years old. And DEHP aggravated inflammation in periodontitis by activating NFκB pathway.PMID:38547731 | DOI:10.1016/j.ecoenv.2024.116252 (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - March 28, 2024 Category: Environmental Health Authors: Wei Wu Wenxiu Jiang Yongmiao Zhou Zhewei Zhang Guoqing Li Chunbo Tang Source Type: research

Construction of Tetrahymena strains with highly active arsenic methyltransferase genes for arsenic detoxification in aquatic environments
This study compared arsenic tolerance, accumulation, methylation, and efflux in 11 Tetrahymena species. Nineteen arsenite (As(III)) S-adenosylmethionine (SAM) methyltransferase (arsM) genes, of which 12 are new discoveries, were identified, and protein sequences were studied. We then constructed recombinant cell lines based on the Tetrahymena thermophila (T. thermophila) wild-type SB210 strain and expressed each of the 19 arsM genes under the control of the metal-responsive the MTT1 promoter. In the presence of Cd2+ and As(V), expression of the arsM genes in the recombinant cell lines was much higher than in the donor spec...
Source: Ecotoxicology and Environmental Safety - March 28, 2024 Category: Environmental Health Authors: Wenjun Xiong Wei Wei Man He Bin Hu Jun Men Jiawei Tu Wei Miao Source Type: research

Cuscuta chinensis flavonoids alleviate ovarian damage in offspring female mice induced by BPA exposure during pregnancy by regulating the central carbon metabolism pathway
This study will improve the information on BPA reproductive damage antagonist drugs and provide a theoretical basis for protecting animal reproductive health.PMID:38537475 | DOI:10.1016/j.ecoenv.2024.116253 (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - March 27, 2024 Category: Environmental Health Authors: Qianhui Zhao Ying Liu Yanan Chuo Xiao Wang Yulan Jiao Wanyu Shi Yongzhan Bao Source Type: research

Wearing face masks as a potential source for inhalation and oral uptake of inanimate toxins - A scoping review
CONCLUSION: Undoubtedly, mask mandates during the SARS-CoV-2 pandemic have been generating an additional source of potentially harmful exposition to toxins with health threatening and carcinogenic properties at population level with almost zero distance to the airways.PMID:38537476 | DOI:10.1016/j.ecoenv.2023.115858 (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - March 27, 2024 Category: Environmental Health Authors: Kai Kisielinski Stefan Hockertz Oliver Hirsch Stephan Korupp Bernd Klosterhalfen Andreas Schnepf Gerald Dyker Source Type: research

Exploring the molecular mechanisms by which per- and polyfluoroalkyl substances induce polycystic ovary syndrome through in silico toxicogenomic data mining
This study utilized toxicogenomics and comparative toxicogenomics databases to analyze data and investigate how PFAS mixtures may contribute to the development of PCOS. The results indicated that 74 genes are associated with both PFAS exposure and PCOS progression. Enrichment analysis suggested that cell cycle regulation and steroid hormone synthesis may be crucial pathways through which PFAS mixtures participate in the development of PCOS, involving important genes such as CCNB1 and SRD5A1. Furthermore, the study identified transcription factors (TFs) and miRNAs that may be involved in the onset and progression of PCOS, c...
Source: Ecotoxicology and Environmental Safety - March 27, 2024 Category: Environmental Health Authors: Xueming Xu Xiaoping Zhang Jiake Chen Xiushuai Du Yi Sun Liqin Zhan Wenxiang Wang Yuchen Li Source Type: research

Environmental cadmium exposure perturbs systemic iron homeostasis via hemolysis and inflammation, leading to hepatic ferroptosis in common carp (Cyprinus carpio L.)
Ecotoxicol Environ Saf. 2024 Mar 26;275:116246. doi: 10.1016/j.ecoenv.2024.116246. Online ahead of print.ABSTRACTCadmium (Cd) pollution is considered a pressing challenge to eco-environment and public health worldwide. Although it has been well-documented that Cd exhibits various adverse effects on aquatic animals, it is still largely unknown whether and how Cd at environmentally relevant concentrations affects iron metabolism. Here, we studied the effects of environmental Cd exposure (5 and 50 μg/L) on iron homeostasis and possible mechanisms in common carp. The data revealed that Cd elevated serum iron, transferrin satu...
Source: Ecotoxicology and Environmental Safety - March 27, 2024 Category: Environmental Health Authors: Wenli Guo Jinjin Zhang Xiaoqian Zhang Quanzhong Ren Guangzhe Zheng Jianxin Zhang Guoxing Nie Source Type: research

Comparison of treatment performance and microbial community evolution of typical dye wastewater by different combined processes
In this study, a combined micro-electrolysis and microbial treatment method was established to treat refractory dye wastewater, and the pivotal factors in the microbial treatment were optimized. In the series and coupled modes, the removal rates of chroma reached 98.75% and 92.50%, and the removal rates of chemical oxygen demand (COD) reached 96.17% and 82.29%, respectively. The high-throughput sequencing results showed that the microbial communities in the microbial system varied at different treatment stages. From the culture stage to the domestication stage, the dominant phylum was Proteobacteria; however, the community...
Source: Ecotoxicology and Environmental Safety - March 27, 2024 Category: Environmental Health Authors: Zhihao Chen Minquan Feng Yibo Wang Xiaohui Ling Source Type: research

An ecotoxicological assessment of a strigolactone mimic used as the active ingredient in a plant biostimulant formulation
Ecotoxicol Environ Saf. 2024 Mar 26;275:116244. doi: 10.1016/j.ecoenv.2024.116244. Online ahead of print.ABSTRACTA risk assessment on the aquatic toxicity of the plant biostimulant strigolactone mimic (2-(4-methyl-5-oxo-2,5-dihydro-furan-2-yloxy)-benzo[de]isoquinoline-1,3-dione (SL-6) was performed using a suite of standardised bioassays representing different trophic groups and acute and chronic endpoints. In freshwater, three trophic groups of algae, crustacea and fish were used. Whilst in seawater, algae (unicellular and macroalgae), Crustacea and Mollusca were employed. In addition, the genotoxicity of SL-6 was determi...
Source: Ecotoxicology and Environmental Safety - March 27, 2024 Category: Environmental Health Authors: Steven J Brooks T ânia Gomes Ana Catarina Almeida Maria Christou Congying Zheng Sergey Shaposhnikov Daria G Popa Florentina Georgescu Florin Oancea Source Type: research

Cuscuta chinensis flavonoids alleviate ovarian damage in offspring female mice induced by BPA exposure during pregnancy by regulating the central carbon metabolism pathway
This study will improve the information on BPA reproductive damage antagonist drugs and provide a theoretical basis for protecting animal reproductive health.PMID:38537475 | DOI:10.1016/j.ecoenv.2024.116253 (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - March 27, 2024 Category: Environmental Health Authors: Qianhui Zhao Ying Liu Yanan Chuo Xiao Wang Yulan Jiao Wanyu Shi Yongzhan Bao Source Type: research

Wearing face masks as a potential source for inhalation and oral uptake of inanimate toxins - A scoping review
CONCLUSION: Undoubtedly, mask mandates during the SARS-CoV-2 pandemic have been generating an additional source of potentially harmful exposition to toxins with health threatening and carcinogenic properties at population level with almost zero distance to the airways.PMID:38537476 | DOI:10.1016/j.ecoenv.2023.115858 (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - March 27, 2024 Category: Environmental Health Authors: Kai Kisielinski Stefan Hockertz Oliver Hirsch Stephan Korupp Bernd Klosterhalfen Andreas Schnepf Gerald Dyker Source Type: research