Ecotoxicology and Environmental Safety This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Metagenomics reveals the variations in functional metabolism associated with greenhouse gas emissions during legume-vegetable rotation process
Ecotoxicol Environ Saf. 2024 Apr 1;275:116268. doi: 10.1016/j.ecoenv.2024.116268. Online ahead of print.ABSTRACTLegume-based rotation is commonly recognized for its mitigation efficiency of greenhouse gas (GHG) emissions. However, variations in GHG emission-associated metabolic functions during the legume-vegetable rotation process remain largely uncharacterized. Accordingly, a soybean-radish rotation field experiment was designed to clarify the responses of microbial communities and their GHG emission-associated functional metabolism through metagenomics. The results showed that the contents of soil organic carbon and tot...
Source: Ecotoxicology and Environmental Safety - April 3, 2024 Category: Environmental Health Authors: Xinxin You Sheng Wang Linna Du Yurong Chen Ting Wang Xiaoxu Bo Source Type: research

In Silico and In Vitro multiple analysis approach for screening naturally derived ligands for red seabream aryl hydrocarbon receptor
In conclusion, we calculated equations to translate the results of an in silico prediction model for ligand screening of rsAHR1 and rsAHR2 transactivation. This ligand screening model can be a powerful tool to quantitatively estimate AHR transactivation of major marine agents to which red seabream may be exposed. The study introduces a new screening approach for potential natural AHR ligands in marine fish, based on homology model-docking energy values of rsAHR1 and rsAHR2, with implications for future agonist development and applications bridging in silico and in vitro data.PMID:38569320 | DOI:10.1016/j.ecoenv.2024.116262...
Source: Ecotoxicology and Environmental Safety - April 3, 2024 Category: Environmental Health Authors: Jong-In Choi Woo-Seon Song Dong-Hee Koh Eun-Young Kim Source Type: research

Nano-CeO < sub > 2 < /sub > activates physical and chemical defenses of garlic (Allium sativum L.) for reducing antibiotic resistance genes in plant endosphere
Ecotoxicol Environ Saf. 2024 Apr 2:116289. doi: 10.1016/j.ecoenv.2024.116289. Online ahead of print.ABSTRACTThe transmission of manure- and wastewater-borne antibiotic-resistant bacteria (ARB) to plants contributes to the proliferation of antimicrobial resistance in agriculture, necessitating effective strategies for preventing the spread of antibiotic resistance genes (ARGs) from ARB in the environment to humans. Nanomaterials are potential candidates for efficiently controlling the dissemination of ARGs. The present study investigated the abundance of ARGs in hydroponically grown garlic (Allium sativum L.) following nano...
Source: Ecotoxicology and Environmental Safety - April 3, 2024 Category: Environmental Health Authors: Yinuo Xu Mengna Tao Wei Xu Lanqing Xu Le Yue Xuesong Cao Feiran Chen Zhenyu Wang Source Type: research

Effects of cadmium and zinc interactions on the physiological biochemistry and enrichment characteristics of Iris pseudacorus
In this study, the effects of single and combined Cd and Zn stress on I. pseudacorus growth and the enrichment of heavy metals in I. pseudacorus seedlings were investigated. The results showed that under Cd (160 μM) and Zn (800 μM) stress, plant growth was significantly inhibited and photosynthetic performance was affected. Cd+Zn200 (160 μM + 200 μM) reduced the levels of malondialdehyde, hydrogen peroxide, and non-protein thiols by 31.29%, 53.20%, and 13.29%, respectively, in the aboveground tissues compared with levels in the single Cd treatment. However, Cd+Zn800 (160 μM + 800 μM) had no effect. Cd and Zn800 inhib...
Source: Ecotoxicology and Environmental Safety - April 2, 2024 Category: Environmental Health Authors: Xiaofang Yu Yujia Liu Linjie Yue Xiaoxuan Zeng Yuwei Huang Hanyue Xue Bin Xu Junrui Zhang Xue Xiao Lijuan Yang Ting Lei Mingyan Jiang Beibei Jiang Suping Gao Xi Li Source Type: research

Nod-like receptor protein 3 inflammasome-mediated pyroptosis contributes to chronic NaAsO < sub > 2 < /sub > exposure-induced fibrotic changes and dysfunction in the liver of SD rats
In this study, we administered varying doses of sodium arsenite (NaAsO2) and 10 mg/kg.bw MCC950 (a particular tiny molecular inhibitor targeting NLRP3) to Sprague-Dawley (SD) rats for 36 weeks to explore the involvement of NLRP3 inflammasome in NaAsO2-induced liver injury. The findings suggested that prolonged exposure to NaAsO2 resulted in pyroptosis in liver tissue of SD rats, accompanied by the fibrotic injury, extracellular matrix (ECM) deposition and liver dysfunction. Moreover, long-term NaAsO2 exposure activated NLRP3 inflammasome, leading to the release of pro-inflammatory cytokines in liver tissue. After treatment...
Source: Ecotoxicology and Environmental Safety - April 2, 2024 Category: Environmental Health Authors: Ying Jin Qian Song Rui He Heng Diao Huijie Gaoyang Lei Wang Lili Fan Dapeng Wang Source Type: research

Integrated network toxicology, molecular docking, and in vivo experiments to elucidate molecular mechanism of aflatoxin B1 hepatotoxicity
Ecotoxicol Environ Saf. 2024 Apr 1;275:116278. doi: 10.1016/j.ecoenv.2024.116278. Online ahead of print.ABSTRACTDue to the rise in temperature and sea level caused by climate change, the detection rate of aflatoxin B1 (AFB1) in food crops has increased dramatically, and the frequency and severity of aflatoxicosis in humans and animals are also increasing. AFB1 has strong hepatotoxicity, causing severe liver damage and even cancer. However, the mechanism of AFB1 hepatotoxicity remains unclear. By integrating network toxicology, molecular docking and in vivo experiments, this research was designed to explore the potential he...
Source: Ecotoxicology and Environmental Safety - April 2, 2024 Category: Environmental Health Authors: Bingjie Ge Kexin Yan Rui Sang Wei Wang Xinman Liu Minghong Yu Xiaotong Liu Qian Qiu Xuemei Zhang Source Type: research

Ambient air pollution exposure and the risk of probable sarcopenia: A prospective cohort study
CONCLUSIONS: Air pollution exposure elevated the risk of developing sarcopenia and related manifestations in a dose-dependent manner, while physical activity maintained protective under this circumstance. Efforts should be made to control air pollution and emphasize the importance of physical activity for skeletal muscle health under this circumstance.PMID:38564861 | DOI:10.1016/j.ecoenv.2024.116273 (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - April 2, 2024 Category: Environmental Health Authors: Lubing Cai Jiale Tan Xinyi Chen Fuchao Wang Xingyu Zhang Jiwu Chen Cong Liu Yaying Sun Source Type: research

Associations of glyphosate exposure and serum sex steroid hormones among 6-19-year-old children and adolescents
Ecotoxicol Environ Saf. 2024 Apr 1;275:116266. doi: 10.1016/j.ecoenv.2024.116266. Online ahead of print.ABSTRACTGlyphosate, ranked as one of the most widely used herbicides in the world, has raised concerns about its potential disruptive effects on sex hormones. However, limited human evidence was available, especially for children and adolescents. The present study aimed to examine the associations between exposure to glyphosate and sex hormones among participants aged 6-19 years, utilizing data from the National Health and Nutrition Examination Survey (NHANES) conducted between 2013 and 2016. Children and adolescents who...
Source: Ecotoxicology and Environmental Safety - April 2, 2024 Category: Environmental Health Authors: Xiaojie Sun Huan Zhang Xiaojing Huang Di Yang Chuansha Wu Hongxiu Liu Ling Zhang Source Type: research

Corrigendum to 'Paracrine signaling of ferroptotic airway epithelium in crystalline silica-induced pulmonary fibrosis augments local fibroblast activation through glycolysis reprogramming' [Ecotoxicol. Environ. Saf. (2024) 271]
Ecotoxicol Environ Saf. 2024 Apr 1;275:116267. doi: 10.1016/j.ecoenv.2024.116267. Online ahead of print.NO ABSTRACTPMID:38564863 | DOI:10.1016/j.ecoenv.2024.116267 (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - April 2, 2024 Category: Environmental Health Authors: Qianmin Li Yi Ling Yu Ma Tao Zhang Youjing Yang Shasha Tao Source Type: research

Bioinformatics-based dynamics of cuproptosis -related indicators in experimental silicosis
Ecotoxicol Environ Saf. 2024 Apr 1;275:116286. doi: 10.1016/j.ecoenv.2024.116286. Online ahead of print.ABSTRACTPneumoconiosis is one of the most serious occupational diseases worldwide. Silicosis due to prolonged inhalation of free silica dust during occupational activities is one of the main types. Cuproptosis is a newly discovered mode of programmed cell death characterized by the accumulation of free copper in the cell, which ultimately leads to cell death. Increased copper in the serum of silicosis patients, suggests that the development of silicosis is accompanied by changes in copper metabolism, but whether cupropto...
Source: Ecotoxicology and Environmental Safety - April 2, 2024 Category: Environmental Health Authors: Jiarui Xia Chenchen Wu Xiaofei Jin Mingcui Ding Chengpeng Zhang Guangjie Hou Changfu Hao Wu Yao Source Type: research

Multiple dietary patterns and the association between long-term air pollution exposure with type 2 diabetes risk: Findings from UK Biobank cohort study
CONCLUSIONS: Multiple forms of healthy DPs help reduce the T2D risk associated with long-term exposure to NO2 and NOX. Our findings indicate that adherence to healthy DPs is a feasible T2D prevention strategy for people long-term suffering from NO2 and NOX pollution.PMID:38564865 | DOI:10.1016/j.ecoenv.2024.116274 (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - April 2, 2024 Category: Environmental Health Authors: Chaonan Fan Wenjuan Wang Shanze Wang Wensu Zhou Li Ling Source Type: research

Aldicarb disturbed bile acid, steroid hormone and oxylipin homeostasis in C57BL/6  J mice
Ecotoxicol Environ Saf. 2024 Apr 1;275:116285. doi: 10.1016/j.ecoenv.2024.116285. Online ahead of print.ABSTRACTMounting evidence has shown that the gut microbiota plays a key role in human health. The homeostasis of the gut microbiota could be affected by many factors, including environmental chemicals. Aldicarb is a carbamate insecticide used to control a variety of insects and nematode pests in agriculture. Aldicarb is highly toxic and its wide existence has become a global public health concern. In our previous study, we have demonstrated that aldicarb disturbed the gut microbial community structure and composition. Ho...
Source: Ecotoxicology and Environmental Safety - April 2, 2024 Category: Environmental Health Authors: Xin Liu Pengcheng Tu Ying Zhang Weichen Xu Jinjun Shan Bei Gao Source Type: research