Elemental Distribution in Animal Carpal and Tarsal Bones Using Differences in X-ray Fluorescence Energy.
In conclusion, our findings suggest that the elemental profiles of bones obtained using two operating voltages could effectively facilitate accurate species discrimination. PMID: 32468226 [PubMed - as supplied by publisher] (Source: Biological Trace Element Research)
Source: Biological Trace Element Research - May 29, 2020 Category: Biology Authors: Pitakarnnop T, Buddhachat K, Pakdeenarong P, Nganvongpanit K Tags: Biol Trace Elem Res Source Type: research

Effects of Nano-Selenium on Antioxidant Capacity in Se-Deprived Tibetan Gazelle (Procapra picticaudata) in the Qinghai-Tibet Plateau.
This study aimed to determine the influence of nano-Se on antioxidant system in Se-deprived P. picticaudata. We analyzed contents of mineral elements in soil, forage, and animal tissue. Blood parameters and antioxidant indexes were also determined. The results showed that Se concentrations in the soil and forage from affected pasture were significantly lower than those in healthy area (P 
Source: Biological Trace Element Research - May 28, 2020 Category: Biology Authors: Shen X, Huo B, Gan S Tags: Biol Trace Elem Res Source Type: research

Iron Overload Resulting from the Chronic Oral Administration of Ferric Citrate Impairs Intestinal Immune and Barrier in Mice.
Abstract Ferric citrate (FC) is an iron-containing phosphate binder used as a food additive for iron supplementation. To explore the potential effect of ferric citrate on intestinal epithelial function, in the present study, we administered the mice orally for 16 weeks with different doses of iron citrate (2.5 mg/day (1.25%), 5 mg/day (2.5%), and 10 mg/day (5.0%)). We found that the iron levels of serum and tissue significantly increased, which caused the body to be in an iron overload state; meanwhile, the villus height, the ratio of villus height to crypt depth, and the number of intraepithel...
Source: Biological Trace Element Research - May 28, 2020 Category: Biology Authors: Luo Q, Lao C, Huang C, Xia Y, Ma W, Liu W, Chen Z Tags: Biol Trace Elem Res Source Type: research

The Effects of Magnesium Supplementation on Lipid Profile Among Type 2 Diabetes Patients: a Systematic Review and Meta-analysis of Randomized Controlled Trials.
Abstract We performed a systematic review and meta-analysis of randomized controlled trials (RCTs) to assess the effects of magnesium (Mg) supplementation on the lipid profile in type 2 diabetes (T2DM) patients. Web of Science, Scopus, PubMed, and Embase databases were searched to infinity until 30 January 2020. Weighted mean differences (WMD) were pooled using a random-effects model. Heterogeneity, sensitivity analysis, and publication bias were reported using standard methods. The pooled analysis of 12 randomized controlled trials indicated that Mg administration led to significant reduction of serum low-density...
Source: Biological Trace Element Research - May 28, 2020 Category: Biology Authors: Asbaghi O, Moradi S, Nezamoleslami S, Moosavian SP, Hojjati Kermani MA, Lazaridi AV, Miraghajani M Tags: Biol Trace Elem Res Source Type: research

Serum Copper and Zinc Levels and Urinary Incontinence in Adult Women.
We examined the associations between serum copper and zinc levels and urinary incontinence (UI) in adult women. Data were retrieved from the 2011-2016 National Health and Nutrition Examination Surveys. Outcomes for multivariate logistic regression were any UI (AUI), urge UI (UUI), stress UI (SUI), mixed UI (MUI), and moderate/severe UI. Questions on urinary incontinence were asked by trained interviewers. The weighted UI prevalences were 44.89% for AUI, 28.12% for UUI, 41.64% for SUI, 17.27% for MUI, and 20.79% for moderate/severe UI in adult women. After adjusting for multiple factors, serum copper levels in the highest q...
Source: Biological Trace Element Research - May 28, 2020 Category: Biology Authors: Gao Y, Liu Y, Wang P, Meng X, Zhang W, Sun Y Tags: Biol Trace Elem Res Source Type: research

Sodium, Magnesium, Calcium, Manganese, Iron, Copper, and Zinc in Serums of Beta Thalassemia Major Patients.
rdere S Abstract Thalassemia major is the most severe form of thalassemia and occurs with the impaired synthesis of β-globin which causes the accumulation of unpaired alpha globin chain. Patients with beta thalassemia major can only survive with periodically safe blood transfusions leading to the accumulation of iron in the bloods of patients, and this causes several endocrinopathies. Although iron overload in thalassemic patients has been extensively studied, there is little information about the levels of other trace elements. The aim of this study was to investigate the differences of serum concentrations ...
Source: Biological Trace Element Research - May 28, 2020 Category: Biology Authors: Şahin A, Er EÖ, Öz E, Yıldırmak ZY, Bakırdere S Tags: Biol Trace Elem Res Source Type: research

Can Zn Be a Critical Element in COVID-19 Treatment?
Abstract The current COVID-19 pandemic caused by SARS-CoV-2 has prompted investigators worldwide to search for an effective anti-viral treatment. A number of anti-viral drugs such as ribavirin, remdesivir, lopinavir/ritonavir, antibiotics such as azithromycin and doxycycline, and anti-parasite such as ivermectin have been recommended for COVID-19 treatment. In addition, sufficient pre-clinical rationale and evidence have been presented to use chloroquine for the treatment of COVID-19. Furthermore, Zn has the ability to enhance innate and adaptive immunity in the course of a viral infection. Besides, Zn supplement ...
Source: Biological Trace Element Research - May 26, 2020 Category: Biology Authors: Rahman MT, Idid SZ Tags: Biol Trace Elem Res Source Type: research

Is Zinc an Important Trace Element on Bone-Related Diseases and Complications? A Meta-analysis and Systematic Review from Serum Level, Dietary Intake, and Supplementation Aspects.
Abstract Bone-related diseases are very common problems, especially in the elderly population. Zinc takes part in the growth and maintenance of healthy bones. This meta-analysis aims to evaluate the effects of zinc supplementation or dietary zinc intake on serum zinc levels and bone turnover markers. A systematical research was performed with 2899 articles in PubMed, WoS, and Scopus for relevant articles in English which have mean/standard deviation values of serum zinc levels, dietary zinc intake/zinc supplementation (mg/day), and bone turnover markers up to February 2020. In the overall analysis, serum zinc leve...
Source: Biological Trace Element Research - May 25, 2020 Category: Biology Authors: Ceylan MN, Akdas S, Yazihan N Tags: Biol Trace Elem Res Source Type: research

Green Approach to Overcome the Resistance Pattern of Candida spp. Using Biosynthesized Silver Nanoparticles Fabricated by Penicillium chrysogenum F9.
In this study, a green approach was developed to control the pathogenic Candida spp. isolated from clinical samples, and prior data collections, ethics approval was obtained. Sixty candida isolates were obtained from the different device-associated infections and identified as Candida albicans, Candida tropicalis, Candida krusei, Candida parapsilosis, and Candida glabrata with prevalence rates 41.6, 38.3, 8.3, 6.6, and 5%, respectively. On the other hand, silver nanoparticles (Ag-NPs) were extra-cellular synthesized by biomass filtrate of previously identified Penicillium chrysogenum strain F9. The physico-chemical charact...
Source: Biological Trace Element Research - May 25, 2020 Category: Biology Authors: Soliman AM, Abdel-Latif W, Shehata IH, Fouda A, Abdo AM, Ahmed YM Tags: Biol Trace Elem Res Source Type: research

Age-Related Effects of Orthovanadate Nanoparticles Involve Activation of GSH-Dependent Antioxidant System in Liver Mitochondria.
In this study, the age-related features of prooxidant/antioxidant balance in blood serum and liver mitochondrial and postmitochondrial fractions of 3 and 18-month-old Wistar male rats treated with orthovanadate nanoparticles (GdVO4/Eu3+, 8 × 25 nm) within 2 months have been investigated. Prooxidant potential-related indexes were the content of lipid hydroperoxides as well as aconitase activity. Activity of glutathione peroxidase, glutathione-S-transferase, glutaredoxin, glutathione reductase, glucose-6-phosphate dehydrogenase, and NADPH-dependent isocitrate dehydrogenase designated the tissue ...
Source: Biological Trace Element Research - May 24, 2020 Category: Biology Authors: Nikitchenko YV, Klochkov VK, Kavok NS, Karpenko NA, Yefimova SL, Nikitchenko IV, Bozhkov AI Tags: Biol Trace Elem Res Source Type: research

Metalloproteomic Strategies for Identifying Proteins as Biomarkers of Mercury Exposure in Serrasalmus rhombeus from the Amazon Region.
alhães Padilha P Abstract This manuscript describes the results of a metalloproteomic study of mercury in samples of muscle and liver tissue of the species Serrasalmus rhombeus, popularly known as black piranha and characterised as the most voracious and aggressive predator in the Brazilian Amazon. The metalloproteomic study involved using two-dimensional electrophoresis (2D PAGE) to fractionate the proteome of the muscle and liver tissue samples, along with atomic absorption spectrometry in a graphite furnace (GFAAS) to identify mercury associated with protein SPOTs and mass spectrometry with electrospray ...
Source: Biological Trace Element Research - May 24, 2020 Category: Biology Authors: de Queiroz JV, Cavecci-Mendonça B, Vieira JCS, Martins RA, de Almeida Assunção AS, Cavallini NG, Dos Santos FA, de Magalhães Padilha P Tags: Biol Trace Elem Res Source Type: research

Insights into the Role of Magnesium Ions in Affecting Osteogenic Differentiation of Mesenchymal Stem Cells.
In this study, we summarized the regulatory mechanisms noted above. PMID: 32449009 [PubMed - as supplied by publisher] (Source: Biological Trace Element Research)
Source: Biological Trace Element Research - May 24, 2020 Category: Biology Authors: Qi T, Weng J, Yu F, Zhang W, Li G, Qin H, Tan Z, Zeng H Tags: Biol Trace Elem Res Source Type: research

Cytosolic and Metallothionein-Bound Hepatic Metals and Detoxification in a Sentinel Teleost, Dules auriga, from Southern Rio de Janeiro, Brazil.
Abstract Dules auriga, a native Brazilian teleost, was applied as a sentinel species regarding metal contamination at Ilha Grande Bay, previously considered a reference site in Southeastern Brazil. Cytosolic (S50) and metallothionein-bound (HTS50) hepatic iron (Fe), zinc (Zn), copper (Cu), manganese (Mn), cadmium (Cd), and silver (Ag) were determined by inductively coupled plasma optical emission spectrometry (ICP-OES), while metallothionein (MT) concentrations were determined by polarography. Ag concentrations in both cytosolic fractions were below the limit of detection. All other HTS50 metal contents were signi...
Source: Biological Trace Element Research - May 23, 2020 Category: Biology Authors: Hauser-Davis RA, Silva-Junior DR, Linde-Arias AR, Vianna M Tags: Biol Trace Elem Res Source Type: research

Selenium, Zinc, Chromium, and Vanadium Levels in Serum, Hair, and Urine Samples of Obese Adults Assessed by Inductively Coupled Plasma Mass Spectrometry.
The objective of this study was to investigate of selenium (Se), zinc (Zn), chromium (Cr), and vanadium (V) levels in blood serum, hair, and urine of adult obese patients. A total of 199 lean and 196 obese subjects were enrolled in the study. Serum, hair, and urinary metal and metalloid analysis were performed by inductively coupled plasma mass spectrometry at NexION 300D (PerkinElmer Inc., USA). The results established that obese subjects were characterized by 47% and 30% lower serum Cr and V levels compared with controls, respectively, whereas serum Se levels exceeded control values by 9%. In contrast, hair Cr, Se, and V...
Source: Biological Trace Element Research - May 23, 2020 Category: Biology Authors: Tinkov AA, Skalnaya MG, Ajsuvakova OP, Serebryansky EP, Chao JC, Aschner M, Skalny AV Tags: Biol Trace Elem Res Source Type: research

Iron and Manganese Retention of Juvenile Zebrafish (Danio rerio) Exposed to Contaminated Dietary Zooplankton (Daphnia pulex)-a Model Experiment.
ábián I, Baranyai E Abstract In present study the effect of iron (Fe) and manganese (Mn) contamination was assessed by modeling a freshwater food web of water, zooplankton (Daphnia pulex), and zebrafish (Danio rerio) under laboratory conditions. Metals were added to the rearing media of D. pulex, and enriched zooplankton was fed to zebrafish in a feeding trial. The elemental analysis of rearing water, zooplankton, and fish revealed significant difference in the treatments compared to the control. In D. pulex the Mn level increased almost in parallel with the dose of supplementation, as well as the Fe...
Source: Biological Trace Element Research - May 23, 2020 Category: Biology Authors: Herman P, Fehér M, Molnár Á, Harangi S, Sajtos Z, Stündl L, Fábián I, Baranyai E Tags: Biol Trace Elem Res Source Type: research

Mitophagy Induced by Mitochondrial Function Damage in Chicken Kidney Exposed to Cr(VI).
This study aimed to investigate mitophagy induced by mitochondrial function damage in chicken kidney exposed to Cr(VI). To explore the mechanism involved, we randomly divided 40 one-day-old Hy-line Brown cockerels into four groups, with each group exposed to different concentrations of Cr(VI), i.e., 0, 10, 30 and 50 mg kg-1, which were orally administered daily for 45 days. Excessive Cr(VI) increased tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6) and chemokine (C-X-C motif) ligand 1(CXCL1) expression and decreased Ca2+-adenosine triphosphatase (Ca2+-ATPase), Mg2+-ATPase and Na+/k+-ATPase a...
Source: Biological Trace Element Research - May 21, 2020 Category: Biology Authors: Wang Y, Wang X, Wang L, Cheng G, Zhang M, Xing Y, Zhao X, Liu Y, Liu J Tags: Biol Trace Elem Res Source Type: research

Correction to: Comparison of Vitamin B12, Vitamin D, and Folic Acid Blood Levels in Plumbism Patients and Controls in Eastern Iran.
Abstract The original version of this article unfortunately contained mistakes. PMID: 32440993 [PubMed - as supplied by publisher] (Source: Biological Trace Element Research)
Source: Biological Trace Element Research - May 21, 2020 Category: Biology Authors: Mehrpour O, Modi M, Mansouri B, Azadi NA, Nakhaee S, Amirabadi A, Anaei-Sarab G, Shirazi FM, Weiss ST Tags: Biol Trace Elem Res Source Type: research

Refer to Evaluation of Possible Human Health Risk of Heavy Metals from the Consumption of Two Marine Fish Species Tenualosa ilisha and Dorosoma cepedianum by Ullah et al. (2019).
PMID: 32440994 [PubMed - as supplied by publisher] (Source: Biological Trace Element Research)
Source: Biological Trace Element Research - May 21, 2020 Category: Biology Authors: Fakhri Y, Sarafraz M Tags: Biol Trace Elem Res Source Type: research

Binding Capacities and Antioxidant Activities of Lactobacillus plantarum and Pichia kudriavzevii Against Cadmium and Lead Toxicities.
This study suggests that these microorganisms can be considered dietary therapeutics against cadmium and lead toxicities. PMID: 32436065 [PubMed - as supplied by publisher] (Source: Biological Trace Element Research)
Source: Biological Trace Element Research - May 20, 2020 Category: Biology Authors: Banwo K, Alonge Z, Sanni AI Tags: Biol Trace Elem Res Source Type: research

Selenium Plays an Anti-Inflammatory Role by Regulation NLRP3 Inflammasome in Staphylococcus aureus-Infected Mouse Mammary Gland.
Abstract Selenium is an essential micronutrient that plays an important role in immunity. However, the mechanism that Selenium modulates mastitis is not fully clear. In this experiment, we investigated whether selenium can inhibit the activation of the NLRP3 inflammasome in a mouse model of Staphylococcus aureus-induced mastitis. Eighty BALB/c female mice were fed with experimental Selenium deficiency basal diet for 2 weeks to achieve the purpose of selenium consumption until pregnancy. Pregnant mice were randomly divided into four groups (control group; selenium supplement group; Staphylococcus aureus infect...
Source: Biological Trace Element Research - May 20, 2020 Category: Biology Authors: Bi CL, Zhang SJ, Shen YZ, Pauline M, Li H, Tang H Tags: Biol Trace Elem Res Source Type: research

Impact of Dietary Selenium on Modulation of Expression of Several Non-Selenoprotein Genes Related to Key Ovarian Functions, Female Fertility, and Proteostasis: a Transcriptome-Based Analysis of the Aging Mice Ovaries.
Abstract Female reproductive (ovarian) aging is characterized by a marked decline in quantity and quality of follicles and oocytes, as well as alterations in the surrounding ovarian stroma. In our previous report, we have shown that dietary selenium (Se) insufficiency and supplementation differentially impacted the reproductive efficiency in aging mice; however, the precise understanding of such modulation is still incomplete. In the present study, we sought to determine the impact of low (mildly low level) and moderately high (medium level) Se diets on expression profile of non-selenoprotein genes in the ovaries ...
Source: Biological Trace Element Research - May 19, 2020 Category: Biology Authors: Qazi IH, Cao Y, Yang H, Angel C, Pan B, Zhou G, Han H Tags: Biol Trace Elem Res Source Type: research

Associations of Serum Selenium Levels in the First Trimester of Pregnancy with the Risk of Gestational Diabetes Mellitus and Preterm Birth: a Preliminary Cohort Study.
Abstract Women with gestational diabetes mellitus (GDM) may have lower serum selenium levels than healthy controls, which may be associated with preterm birth. We explored the association of serum selenium levels in early pregnancy with the risk of GDM and preterm birth among Chinese women. We included 398 women with a singleton pregnancy, who were followed up prospectively from the first prenatal visit until delivery. Serum selenium levels were measured in the first trimester. After delivery, data concerning mothers and their children were sourced from medical records by researchers who were blind to the particip...
Source: Biological Trace Element Research - May 16, 2020 Category: Biology Authors: Liu PJ, Yao A, Ma L, Chen XY, Yu SL, Liu Y, Hou YX Tags: Biol Trace Elem Res Source Type: research

Correction to: Influence of Exogenous Silicon Addition on Aluminium Tolerance in Rice Seedlings.
Abstract The original version of this article unfortunately contained a mistake. PMID: 32415323 [PubMed - as supplied by publisher] (Source: Biological Trace Element Research)
Source: Biological Trace Element Research - May 15, 2020 Category: Biology Authors: Singh VP, Tripathi DK, Kumar D, Chauhan DK Tags: Biol Trace Elem Res Source Type: research

Study of Essential and Toxic Metal Imbalances in the Scalp Hair of Thyroid Cancer Patients in Comparison with Healthy Donors.
Abstract Thyroid cancer is among the most common type of head and neck cancer; diet, age, gender and environmental factors play vital roles in its malignancy. The present study was carried out to assess the imbalances in the contents of trace metals due to onset and progression of thyroid cancer. Scalp hair was used as matrix for the evaluation of toxic and trace metals. Quantification of the metals was done through atomic absorption spectrometry. In comparison with healthy subjects, the thyroid cancer patients revealed significantly higher median levels of Mn (71%), Co (64%), Cr (55%), K (49%), Fe (45%), Mg (42%)...
Source: Biological Trace Element Research - May 14, 2020 Category: Biology Authors: Bibi K, Shah MH Tags: Biol Trace Elem Res Source Type: research

Alterations in Blood Metabolic Parameters of Immature Mice After Subchronic Exposure to Cobalt Chloride.
Abstract The wide use of cobalt (Co) in food, industry, and medical devices requires full elucidation of its biological effects on tissues and organs. The aim was to assess serum metabolic alterations in immature mice after subchronic exposure to CoCl2. Pregnant ICR mice were subjected to a daily dose of 75 mg cobalt chloride/kg body weight (CoCl2x6H2O) 2-3 days before they gave birth, and treatment continued until days 25 and 30 after delivery. The compound was dissolved in and obtained with regular tap water. ICP-DRC-MS analysis showed significantly elevated serum Co2+ and diverse alterations in metabo...
Source: Biological Trace Element Research - May 13, 2020 Category: Biology Authors: Vladov I, Petrova E, Pavlova E, Tinkov AA, Ajsuvakova OP, Skalny AV, Gluhcheva Y Tags: Biol Trace Elem Res Source Type: research

Interleukin-4 Administration or Zinc Supplementation Is Effective in Preventing Zinc Deficiency-Induced Hemolytic Anemia and Splenomegaly.
Abstract Nutritional zinc deficiency aggravates inflammation, subsequently causing anemia and splenomegaly in rats; however, the mechanism underlying such splenomegaly remains poorly understood. Therefore, in this study, we aimed to elucidate the mechanisms underlying the splenomegaly and anemia occurring in zinc-deficient rats and investigate whether these effects of zinc deficiency could be reversed by interleukin (IL)-4 administration or zinc supplementation. Five-week-old male Sprague-Dawley rats were fed a standard diet; fed a zinc-deficient diet (n = 7 each) and injected with saline or IL-4; or...
Source: Biological Trace Element Research - May 13, 2020 Category: Biology Authors: Kido T, Hachisuka E, Suka M, Yanagisawa H Tags: Biol Trace Elem Res Source Type: research

Zinc Deficiency Aggravation of ROS and Inflammatory Injury Leading to Renal Fibrosis in Mice.
Abstract Zinc (Zn) is a trace element with a variety of anti-inflammatory and antioxidant effects. Zn deficiency is related to tissue fibrosis. The present study was designed to investigate the effect of Zn on renal fibrosis. Mouse models were successfully established by feeding mice diets with different concentrations of Zn. Zn deficiency induced a decrease in Zn levels in kidney tissue. The results also revealed renal vasodilation, hyperemia, and inflammatory cell infiltration, and the levels of creatinine and urea nitrogen were increased. Furthermore, the TUNEL results showed a large degree of renal cell necros...
Source: Biological Trace Element Research - May 12, 2020 Category: Biology Authors: Xu R, Chen MY, Liang W, Chen Y, Guo MY Tags: Biol Trace Elem Res Source Type: research

Effects of Nano-Zinc on Immune Function in Qianbei-Pockmarked Goats.
This study aimed to determine the influence of nano-zinc on immune function in zinc-deprived goats. We analyzed the mineral concentrations in soil, forage, and animal tissue. Blood parameters and immune indexes were also determined. Results showed that the zinc concentrations in soil and forage from affected area were significantly lower than those in control area (P
Source: Biological Trace Element Research - May 11, 2020 Category: Biology Authors: Song C, Gan S, He J, Shen X Tags: Biol Trace Elem Res Source Type: research

Precision Harvesting of Medicinal Plants: Elements and Ash Content of Hyssop (Hyssopus officinalis L.) as Affected by Harvest Height.
Abstract To investigate the effect of harvest height on the amassed elements and ash content of Hyssop (Hyssopus officinalis L.), an experiment was conducted in a randomized complete block design with three replications. Treatments included four harvest heights, i.e., 15, 25, 35, and 45 cm (from the tip of the plant) and the residual stalks. The dependent variables were the amassed content of elements N, K, P, Ca, Mg, Cu, Zn, and Pb in different heights of the plant and the associated ash content (total ash (TA), acid-insoluble ash (AA), and water-insoluble ash (WA)). The results showed that by moving from th...
Source: Biological Trace Element Research - May 11, 2020 Category: Biology Authors: Saebi A, Minaei S, Mahdavian AR, Ebadi MT Tags: Biol Trace Elem Res Source Type: research

Contamination of Fishery Products with Mercury, Cadmium, and Lead in Tunisia: Level's Estimation and Human Health Risk Assessment.
Abstract The levels of metallic trace elements were determined in fishery products sampled from Tunisian fishing ports. Mean concentrations were 0.20 ± 0.01, 0.05 ± 0.01, and 0.10 ± 0.01 mg/kg in fish flesh for Hg, Cd, and Pb, respectively. The mean concentrations of these elements were below regulatory thresholds; however, we also detected some specimens with higher levels. The mercury level showed a significant difference between fish categories, region, and year of sampling (p 
Source: Biological Trace Element Research - May 9, 2020 Category: Biology Authors: Zrelli S, Amairia S, Chaabouni M, Oueslati W, Chine O, Nachi Mkaouar A, Cheikhsbouii A, Ghorbel R, Zrelli M Tags: Biol Trace Elem Res Source Type: research

Selenium Deficiency via the TLR4/TRIF/NF- κB Signaling Pathway Leading to Inflammatory Injury in Chicken Spleen.
Selenium Deficiency via the TLR4/TRIF/NF-κB Signaling Pathway Leading to Inflammatory Injury in Chicken Spleen. Biol Trace Elem Res. 2020 May 09;: Authors: Zhang R, Guo R, Liu Q, Li G, Sun B, Huang X Abstract The aim of the present study was to investigate the effect of selenium (Se) deficiency on the expression of the toll-like receptor (TLR) signal transduction pathway in the spleen of chickens and explore the relationship between the TLR4/TRIF/NF-κB signaling pathway and inflammatory spleen injury. A total of 200 one-day-old healthy broilers were allocated to two groups. The experimenta...
Source: Biological Trace Element Research - May 9, 2020 Category: Biology Authors: Zhang R, Guo R, Liu Q, Li G, Sun B, Huang X Tags: Biol Trace Elem Res Source Type: research

Boron Attenuates Heat Stress-Induced Apoptosis by Inhibiting Endoplasmic Reticulum Stress in Mouse Granulosa Cells.
This study provides novel insights into the benefits of using boron against heat-induced apoptosis. PMID: 32385716 [PubMed - as supplied by publisher] (Source: Biological Trace Element Research)
Source: Biological Trace Element Research - May 9, 2020 Category: Biology Authors: Xiong Y, Jin E, Yin Q, Che C, He S Tags: Biol Trace Elem Res Source Type: research

The Effects of Magnesium Supplementation on Blood Pressure and Obesity Measure Among Type 2 Diabetes Patient: a Systematic Review and Meta-analysis of Randomized Controlled Trials.
In this study, we aimed to systematically review the literature to evaluate the effects of magnesium (Mg) supplementation on blood pressure (BP) and obesity measure among patients with type 2 diabetes mellitus (T2DM). Major electronic databases of Web of Science, the Cochrane library, PubMed, and Scopus were searched completely from the inception until 15 October 2019 to identify randomized clinical trials (RCTs) pertaining to the topic of interest. All outcomes were pooled using a random-effects model and expressed as weighted mean differences (WMD) with 95% confidential intervals (CI). Heterogeneity, sensitivity analysis...
Source: Biological Trace Element Research - May 8, 2020 Category: Biology Authors: Asbaghi O, Hosseini R, Boozari B, Ghaedi E, Kashkooli S, Moradi S Tags: Biol Trace Elem Res Source Type: research

Green Synthesis of Metallic Nanoparticles and Their Prospective Biotechnological Applications: an Overview.
Abstract The green synthesis of nanoparticles (NPs) using living cells is a promising and novelty tool in bionanotechnology. Chemical and physical methods are used to synthesize NPs; however, biological methods are preferred due to its eco-friendly, clean, safe, cost-effective, easy, and effective sources for high productivity and purity. High pressure or temperature is not required for the green synthesis of NPs, and the use of toxic and hazardous substances and the addition of external reducing, stabilizing, or capping agents are avoided. Intra- or extracellular biosynthesis of NPs can be achieved by numerous bi...
Source: Biological Trace Element Research - May 6, 2020 Category: Biology Authors: Salem SS, Fouda A Tags: Biol Trace Elem Res Source Type: research

Blood Magnesium Level and Selected Oxidative Stress Indices in Lead-Exposed Workers.
Abstract Occupational exposure to lead is one of the important hazards to human global population. Lead interferes with divalent cations, such as calcium, magnesium, and iron. Magnesium is the fourth most common mineral in the human body and a cofactor in more than 325 enzymes. There are many disorders associated with magnesium deficiency. It has been postulated that hypomagnesemia promotes oxidative stress. Study population included 232 male employees of lead-zinc works and was divided into two sub-groups based on the median of magnesium serum level: low magnesium level (L-Mg) group and high magnesium level (H-Mg...
Source: Biological Trace Element Research - May 6, 2020 Category: Biology Authors: Wyparło-Wszelaki M, Wąsik M, Machoń-Grecka A, Kasperczyk A, Bellanti F, Kasperczyk S, Dobrakowski M Tags: Biol Trace Elem Res Source Type: research

Speciation Analysis of Chromium in Chromium-Enriched Yeast by Ion Chromatography-Inductively Coupled Plasma Mass Spectrometry.
Abstract Chromium-enriched yeast (CrY) is a popular Cr dietary supplement, but suitable speciation analysis of highly toxic Cr(VI) in CrY is not available. Ion chromatography-inductively coupled plasma mass spectrometry method was firstly developed and validated for the quantification of Cr(III) and Cr(VI). Ultrasound-assisted weakly alkaline EDTA solution combined with boiling was used to extract two Cr species in CrY. Two species were separated on two successive anion-exchange columns using a mobile phase of 0.6 mmol/L EDTA and 76 mmol/L NH4NO3 solution. The method was sensitive, accurate (92.4-100.9%)...
Source: Biological Trace Element Research - May 5, 2020 Category: Biology Authors: Zhang SQ, Cheng SH, Shen S, Luo BY, Zhang Y Tags: Biol Trace Elem Res Source Type: research

Comparison the Zn-Threonine, Zn-Methionine, and Zn Oxide on Performance, Egg Quality, Zn Bioavailability, and Zn Content in Egg and Excreta of Laying Hens.
Abstract The experiment was conducted to investigate the effect of supplementary zinc-threonine (Zn-Thr), zinc-methionine (Zn-Met), and zinc oxide (ZnO) on the laying performance, egg quality, Zn content in egg and excreta. One hundred and sixty hens (Hy-Line W36) were randomly divided into 10 treatments with 4 replications of 4 hens each. During the first 4 weeks, groups were fed a corn-soy basal diet without extra zinc (30.3 mg Zn/kg diet) to depletion storage zinc from the body and it was used as the control diet. During the ensuing 10 weeks from 36 to 45 weeks of age, 3 levels of 30, 60, an...
Source: Biological Trace Element Research - May 4, 2020 Category: Biology Authors: Behjatian Esfahani M, Moravej H, Ghaffarzadeh M, Nehzati Paghaleh GA Tags: Biol Trace Elem Res Source Type: research

Associations of TMPRSS6 Polymorphisms with Gestational Diabetes Mellitus in Chinese Han Pregnant Women: a Preliminary Cohort Study.
Abstract Body iron status is likely to be associated with type 2 diabetes (T2DM) and gestational diabetes mellitus (GDM); transmembrane protease serine 6 (TMPRSS6) polymorphisms may be associated with T2DM risk through their effects on body iron status. However, it remains unknown whether the TMPRSS6 single nucleotide polymorphisms (SNPs) affect the risk of GDM development. We aimed to determine whether the TMPRSS6 SNPs rs855791 (V736A) and rs4820268 (D521D) are associated with the risk of GDM in pregnant women. The two SNPs in TMPRSS6 gene were genotyped and examined for their associations with body iron status a...
Source: Biological Trace Element Research - May 3, 2020 Category: Biology Authors: Liu PJ, Yao A, Chen XY, Liu Y, Ma L, Hou YX Tags: Biol Trace Elem Res Source Type: research

Refinement Impairments of Verbal-Performance Intelligent Quotient in Children Exposed to Fluoride Produced by Coal Burning.
Abstract To explore the relationship between total intelligence quotient (IQ), verbal intelligence quotient (VIQ), performance intelligence quotient (PIQ), and fluoride exposure in children aged 8-12 years in coal-burning fluorosis area of Dafang County, Guizhou Province, China. The Wechsler Intelligence Scale for Children Revised in China (WISC-CR) was used to test the total IQ, VIQ, and PIQ in 99 children aged 8-12 years (55 in dental fluorosis group and 44 in control group). The differences in the intellectual levels between the two groups were compared, and the correlation between the intellectual le...
Source: Biological Trace Element Research - May 3, 2020 Category: Biology Authors: Lou D, Luo Y, Liu J, Zheng D, Ma R, Chen F, Yu Y, Guan Z Tags: Biol Trace Elem Res Source Type: research

Comparison of Thymulin Activity with Other Measures of Marginal Zinc Deficiency.
This study compared thymulin activity with four other zinc status measures in rats fed zinc at either 5 or 25 ppm. Rats fed the lower zinc showed the following results compared with rats with adequate zinc intake: serum thymulin activity 61% lower, serum zinc 31% lower, serum extracellular superoxide dismutase 18% lower, serum 5'-nucleotidase activity 26% lower, and liver metallothionein 28% lower. Thus, thymulin activities showed more sensitivity to restricted zinc intake than did four other parameters. PMID: 32363520 [PubMed - as supplied by publisher] (Source: Biological Trace Element Research)
Source: Biological Trace Element Research - May 3, 2020 Category: Biology Authors: DiSilvestro RA, Dardenne M, Joseph E Tags: Biol Trace Elem Res Source Type: research

The Effect of Inorganic and Organic Zinc Supplementation on Growth Performance, Mineral Profile and Gene Expression Pattern of GLUT1 in Malabari Kids.
The objective of this experiment was to study and compare the effects of dietary supplementation of organic and inorganic zinc (Zn) on growth performance, nutrient utilisation and gene expression pattern of glucose transporter protein in peripheral blood mononuclear cells (PBMC) in Malabari kids. Fifteen, 3-4-month-old goat kids were divided into three groups uniformly by using completely randomised design (CRD). Group G1 was fed on basal diet as per NRC requirement, and G2 and G3 were fed on basal diet + 40 ppm Zn as inorganic zinc sulphate (ZnSO4) and 40 ppm Zn as organic Zn methionine, respectively, for a peri...
Source: Biological Trace Element Research - May 3, 2020 Category: Biology Authors: Chavan SJ, Varadan D, Ravishankar C, Vazhoor B, Sebastian R, Chulliparambil S, Prakash P Tags: Biol Trace Elem Res Source Type: research

Multi-element Analysis of Brain Regions from South African Cadavers.
In conclusion, this is the first article to report the trace element concentrations of brain regions from a South African population. Low magnesium levels in the brain may be linked to a dietary deficiency, and migraines, depression and epilepsy have been linked to low magnesium levels. Future research should be directed to increase the dietary intake of magnesium. PMID: 32361883 [PubMed - as supplied by publisher] (Source: Biological Trace Element Research)
Source: Biological Trace Element Research - May 2, 2020 Category: Biology Authors: Cilliers K, Muller CJF Tags: Biol Trace Elem Res Source Type: research

Bone Mineral Density in Population Long-Term Exposed to Rare Earth Elements from a Mining Area of China.
This study aims to investigate the effects of individuals' exposure to rare earth elements (REEs) on bone metabolism. Adopting the inductively coupled plasma mass spectrometry, we measured REEs and eight other elements (Ca, Fe, Cu, Na, K, Zn, Mg, and P) in the hair of 53 miners exposed to REEs from Baiyunebo and 57 healthy farmers as the control group. Furthermore, bone mineral density (BMD) in both groups was assessed by dual-energy X-ray absorptiometry. Analysis of variance showed that the concentrations of La, Ce, Pr, Nd, Tb, Ho, Tm, and Yb in male hair of exposed group were significantly higher compared with the contro...
Source: Biological Trace Element Research - May 2, 2020 Category: Biology Authors: Liu H, Liu H, Yang Z, Wang K Tags: Biol Trace Elem Res Source Type: research

Determination of the Non-metallic Elements in Herbal Tea by Inductively Coupled Plasma Tandem Mass Spectrometry.
Abstract The feasibility of using inductively coupled plasma tandem mass spectrometry (ICP-MS/MS) to overcome spectral overlaps in the determination of non-metallic elements was investigated. The contents of Si, P, S, Cl, Br, and I in herbal tea were determined by using ICP-MS/MS after microwave digestion. In the MS/MS mode, O2 and H2 were consecutively used as reaction gases. Low background equivalent concentration (BEC) and limit of detection (LOD) of analytes were obtained when using O2 mass shift, H2 mass shift, and H2 on-mass methods. The LODs for Si, P, S, Cl, Br, and I were 0.41, 0.048, 0.34, 0.76, 0.055, a...
Source: Biological Trace Element Research - May 2, 2020 Category: Biology Authors: Fu L, Xie H, Huang J, Chen L Tags: Biol Trace Elem Res Source Type: research

Association of Urinary and Blood Concentrations of Heavy Metals with Measures of Bone Mineral Density Loss: a Data Mining Approach with the Results from the National Health and Nutrition Examination Survey.
Abstract Osteoporosis and its consequence of fragility fracture represent a major public health problem. Human exposure to heavy metals has received considerable attention over the last decades. However, little is known about the influence of co-exposure to multiple heavy metals on bone density. The present study aimed to examine the association between exposure to metals and bone mineral density (BMD) loss. Blood and urine concentrations of 20 chemical elements were selected from 3 cycles (2005-2010) NHANES (National Health and Nutrition Examination Survey), in which we included white women over 50 year...
Source: Biological Trace Element Research - April 30, 2020 Category: Biology Authors: Ximenez JPB, Zamarioli A, Kacena MA, Barbosa RM, Barbosa F Tags: Biol Trace Elem Res Source Type: research

Plasma and Nail Zinc Concentrations, But Not Hair Zinc, Respond Positively to Two Different Forms of Preventive Zinc Supplementation in Young Laotian Children: a Randomized Controlled Trial.
This study investigated the effects of daily preventive zinc supplementation on hair and nail zinc concentrations compared with a control group. In a randomized controlled trial, 6- to 23-month-old children (n = 3407) in Lao PDR were randomly assigned to one of four groups and followed for ~ 36 weeks: daily preventive zinc dispersible tablet (7 mg/d; PZ), daily micronutrient powder (10 mg zinc/d; MNP), therapeutic zinc supplements for diarrhea treatment (20 mg/d for 10 days; TZ), or daily placebo powder (Control). Plasma, hair, and nail zinc concentrations were assessed in a sub-...
Source: Biological Trace Element Research - April 30, 2020 Category: Biology Authors: Wessells KR, Brown KH, Arnold CD, Barffour MA, Hinnouho GM, Killilea DW, Kounnavong S, Hess SY Tags: Biol Trace Elem Res Source Type: research

Correction to: Effect of Endoxylanase and Iron Oxide Nanoparticles on Performance and Histopathological Features in Broilers.
Abstract The original version of this article unfortunately contained a mistake. The name of "Muhammad Talha Yasin" is now corrected in the author group of this article. PMID: 32356208 [PubMed - as supplied by publisher] (Source: Biological Trace Element Research)
Source: Biological Trace Element Research - April 30, 2020 Category: Biology Authors: Rehman H, Akram M, Kiyani MM, Yasin MT, Ghani A, Saggu JI, Shah SSH, Khalid ZM, Bokhari SAI Tags: Biol Trace Elem Res Source Type: research

Possible Mechanisms of Liver Injury Induced by Cadmium Sulfide Nanoparticles in Rat.
Abstract Cadmium is primarily utilized in the construction of particles known as quantum dots. Hepatotoxicity caused by microparticles of cadmium is very well known; however, toxicity of nanoparticles of cadmium is not well understood. The present study describes the toxicity of cadmium sulfide nanoparticles (CdSNPs) in the liver of rat. Adult Wistar rats were administered CdSNPs (10 mg/kg) on alternate days for 45 days. Serum enzymes (ALT, AST, ALP), biomarkers of lipid peroxidation (MDA, H2O2, and NO), and metallothionein concentration were determined. Histopathological and TEM observations were also m...
Source: Biological Trace Element Research - April 28, 2020 Category: Biology Authors: Rana K, Verma Y, Rana SVS Tags: Biol Trace Elem Res Source Type: research

The Role of Lead, Manganese, and Zinc in Autism Spectrum Disorders (ASDs) and Attention-Deficient Hyperactivity Disorder (ADHD): a Case-Control Study on Syrian Children Affected by the Syrian Crisis.
This study aims to investigate the levels of lead, manganese, and zinc in each of ASD, ADHD, and ASD with comorbid ADHD in Syrian children born or grown during the Syrian crisis. Lead and manganese were measured in the whole blood, and zinc was measured in the serum in 31 children with ASD, 29 children with ADHD, and 11 children with ASD with comorbid ADHD (ASD-C) compared with 30 healthy children, their ages ranged between 3 and 12 years. Blood lead levels were higher in the groups of ASD-C (245.42%), ASD (47.57%), and ADHD (14.19%) compared with control. Lead levels were significantly higher in children with ASD in ...
Source: Biological Trace Element Research - April 28, 2020 Category: Biology Authors: Hawari I, Eskandar MB, Alzeer S Tags: Biol Trace Elem Res Source Type: research

Associations of Blood Heavy Metals with Uric Acid in the Korean General Population: Analysis of Data from the 2016-2017 Korean National Health and Nutrition Examination Survey.
In conclusion, blood lead and mercury levels were positively associated with uric acid level, but blood cadmium level was inversely associated with uric acid level and hyperuricemia in women. PMID: 32342340 [PubMed - as supplied by publisher] (Source: Biological Trace Element Research)
Source: Biological Trace Element Research - April 27, 2020 Category: Biology Authors: Park J, Kim Y Tags: Biol Trace Elem Res Source Type: research