Role of Nitric Oxide, TNF- α and Caspase-3 in Lead Acetate-Exposed Rats Pretreated with Aqueous Rosmarinus officinalis Leaf Extract
Biol Trace Elem Res. 2023 Nov 28. doi: 10.1007/s12011-023-03974-9. Online ahead of print.ABSTRACTLead (Pb) toxicity is a worldwide significant public health challenge causing several neurological disorders. Reports indicate that plants rich in antioxidants, such as Rosmarinus officinalis (RO), can counteract Pb accumulation and its toxicity in the brain. Due to a dearth of literature evidence demonstrating the protective activity of RO against Pb toxicity, this study investigated such activity in Wistar rats. Thirty-six Wistar rats were allocated into six groups (n=6), namely I (control), II (lead acetate [Pb]; 100 mg/kg b...
Source: Biological Trace Element Research - November 27, 2023 Category: Biology Authors: Adaze Bijou Enogieru Etinosa Nathan Iyoha Source Type: research

Association of Blood Selenium Levels with Diabetes and Heart Failure in American General Adults: a Cross-sectional Study of NHANES 2011-2020 pre
This study utilized data from four survey cycles from NHANES 2011-2020 pre. Blood selenium levels were considered as both a continuous variable and quartiles, and logistic regression was employed to investigate the associations between blood selenium levels with diabetes and heart failure. Nonlinear relationships were examined by restricted cubic spline regression. The analysis included a total of 16311 participants aged 20 years or older. After adjustment for all potential confounder, we found when the blood selenium levels increased by 10 ug/L, the average risk of diabetes increased by 4.2% (95% CI: 1.5%, 7.0%), and the ...
Source: Biological Trace Element Research - November 23, 2023 Category: Biology Authors: Chongyang Zhang Qingjia Zeng Xinyao Liu Qile He Jinyao Zhang Shanshan Zhao Hongpu Hu Source Type: research

Comprehensive Insights into the Health Effects of Selenium Exposure and Supplementation Among the Chinese Community Middle-Aged and Elderly: a Combined Retrospective Cohort Study and Intervention Study
Biol Trace Elem Res. 2023 Nov 24. doi: 10.1007/s12011-023-03963-y. Online ahead of print.ABSTRACTSelenium (Se) is an essential trace element for maintaining human health, for example, plays a crucial role in preventing aging-related diseases. However, most studies on the health effects of Se among the community middle-aged and elderly have been observational or the health indices were single, and the related study among the Chinese population is limited. Additionally, China is recognized as among the countries facing a significant deficiency in Se, and Se contents in the human body may decrease with age. Therefore, a two-s...
Source: Biological Trace Element Research - November 23, 2023 Category: Biology Authors: Chen Li Xiangwen Peng Jiayang Zheng Kexin Shi Liqiang Qin Qinyi Yang Zhangmin Wang Ying Liu Lei Huang Source Type: research

Association of Blood Selenium Levels with Diabetes and Heart Failure in American General Adults: a Cross-sectional Study of NHANES 2011-2020 pre
This study utilized data from four survey cycles from NHANES 2011-2020 pre. Blood selenium levels were considered as both a continuous variable and quartiles, and logistic regression was employed to investigate the associations between blood selenium levels with diabetes and heart failure. Nonlinear relationships were examined by restricted cubic spline regression. The analysis included a total of 16311 participants aged 20 years or older. After adjustment for all potential confounder, we found when the blood selenium levels increased by 10 ug/L, the average risk of diabetes increased by 4.2% (95% CI: 1.5%, 7.0%), and the ...
Source: Biological Trace Element Research - November 23, 2023 Category: Biology Authors: Chongyang Zhang Qingjia Zeng Xinyao Liu Qile He Jinyao Zhang Shanshan Zhao Hongpu Hu Source Type: research

Comprehensive Insights into the Health Effects of Selenium Exposure and Supplementation Among the Chinese Community Middle-Aged and Elderly: a Combined Retrospective Cohort Study and Intervention Study
Biol Trace Elem Res. 2023 Nov 24. doi: 10.1007/s12011-023-03963-y. Online ahead of print.ABSTRACTSelenium (Se) is an essential trace element for maintaining human health, for example, plays a crucial role in preventing aging-related diseases. However, most studies on the health effects of Se among the community middle-aged and elderly have been observational or the health indices were single, and the related study among the Chinese population is limited. Additionally, China is recognized as among the countries facing a significant deficiency in Se, and Se contents in the human body may decrease with age. Therefore, a two-s...
Source: Biological Trace Element Research - November 23, 2023 Category: Biology Authors: Chen Li Xiangwen Peng Jiayang Zheng Kexin Shi Liqiang Qin Qinyi Yang Zhangmin Wang Ying Liu Lei Huang Source Type: research

Association of Blood Selenium Levels with Diabetes and Heart Failure in American General Adults: a Cross-sectional Study of NHANES 2011-2020 pre
This study utilized data from four survey cycles from NHANES 2011-2020 pre. Blood selenium levels were considered as both a continuous variable and quartiles, and logistic regression was employed to investigate the associations between blood selenium levels with diabetes and heart failure. Nonlinear relationships were examined by restricted cubic spline regression. The analysis included a total of 16311 participants aged 20 years or older. After adjustment for all potential confounder, we found when the blood selenium levels increased by 10 ug/L, the average risk of diabetes increased by 4.2% (95% CI: 1.5%, 7.0%), and the ...
Source: Biological Trace Element Research - November 23, 2023 Category: Biology Authors: Chongyang Zhang Qingjia Zeng Xinyao Liu Qile He Jinyao Zhang Shanshan Zhao Hongpu Hu Source Type: research

Comprehensive Insights into the Health Effects of Selenium Exposure and Supplementation Among the Chinese Community Middle-Aged and Elderly: a Combined Retrospective Cohort Study and Intervention Study
Biol Trace Elem Res. 2023 Nov 24. doi: 10.1007/s12011-023-03963-y. Online ahead of print.ABSTRACTSelenium (Se) is an essential trace element for maintaining human health, for example, plays a crucial role in preventing aging-related diseases. However, most studies on the health effects of Se among the community middle-aged and elderly have been observational or the health indices were single, and the related study among the Chinese population is limited. Additionally, China is recognized as among the countries facing a significant deficiency in Se, and Se contents in the human body may decrease with age. Therefore, a two-s...
Source: Biological Trace Element Research - November 23, 2023 Category: Biology Authors: Chen Li Xiangwen Peng Jiayang Zheng Kexin Shi Liqiang Qin Qinyi Yang Zhangmin Wang Ying Liu Lei Huang Source Type: research

Effects of Zinc Supplementation on Inflammatory Status and Nonalcoholic Steatohepatitis in Overweight or Obese Children: a Randomized Clinical Trial
Biol Trace Elem Res. 2023 Nov 22. doi: 10.1007/s12011-023-03954-z. Online ahead of print.ABSTRACTThe purpose of the present clinical trial was to determine the impact of zinc supplementation on serum liver enzymes, steatosis severity, lipid profile, and inflammatory status in overweight or obese children with nonalcoholic steatohepatitis (NASH). This randomized controlled trial was conducted by enrolling 60 children with NASH, aged 10-18 years old. The participants were randomly assigned to two groups that received either 30 mg/day of elemental zinc or placebo for 16 weeks. The severity of liver steatosis was evaluated usi...
Source: Biological Trace Element Research - November 22, 2023 Category: Biology Authors: Vahidreza Ostadmohammadi Mohammad Javad Namazi Mahsa Rezasoltani Davood Kheirkhah Mohammad Rajabi Alireza Sharif Abbas Taghavi Ardakani Fariba Raygan Amelia A Assareh Mohammad Reza Sharif Source Type: research

Exploration of Toxic and Essential Metals in Popular Rice Grains of Bangladesh and Associated Human Health Risk Implications
Biol Trace Elem Res. 2023 Nov 22. doi: 10.1007/s12011-023-03962-z. Online ahead of print.ABSTRACTIn order to evaluate the benefits as well as the impacts of essential and toxic metals regarding human health, the six common rice grains (katarivhog, bashful, banglamoti, najirshail, branded miniket and loose miniket) were collected from four wholesale markets in Dhaka, the capital of Bangladesh, and were analyzed with different atomic absorption spectroscopy (AAS) techniques. The mean concentrations of the toxic metals Pb, Cd, Cr, and As had 0.299 ± 0.017, 0.157 ± 0.012, 1.33 ± 0.084, and 0.120 ± 0.006 mg/kg, respectively...
Source: Biological Trace Element Research - November 22, 2023 Category: Biology Authors: M Mozammal Hosen M Nur E Alam F S Tonni S R Khan M A Maksud L N Lutfa A K M Atique Ullah Rehena Begum Quamrun Nahar Shamshad B Quraishi Source Type: research

Effects of Dietary Selenium Yeast Supplementation on Oxidative Biomarkers of the Brain and Blood in Goats
Biol Trace Elem Res. 2023 Nov 22. doi: 10.1007/s12011-023-03966-9. Online ahead of print.ABSTRACTThe present study evaluated the effects of dietary selenium yeast (SY) on the brain, CSF, and blood of 30 crossbreed goats (5-6 months of age) of both sexes. After the acclimatization of 2 weeks, they were randomly separated into two groups (n = 15) named C and SY groups. The C group received only a basal diet, while SY received a basal diet along with 0.3 mg/kg/diet of SY (Sel-Plex®) in total 0.035 mg/kg/diet of SY for 10 weeks. Se concentration (µg /g dry weight) in 15 different parts of the goat's brain was accessed, and r...
Source: Biological Trace Element Research - November 22, 2023 Category: Biology Authors: Iqra Bano Moolchand Malhi Hira Sajjad Talpur Source Type: research

Association Between Multiple Metal(loid)s Exposure and Blood Lipid Levels: Evidence from a Cross-Sectional Study of Southeastern China
Biol Trace Elem Res. 2023 Nov 22. doi: 10.1007/s12011-023-03951-2. Online ahead of print.ABSTRACTExposure to essential and toxic metals occurs simultaneously as a mixture in real-life. However, there is no consensus regarding the effects of co-exposure to multiple metal(loid)s (designated hereafter metals) on blood lipid levels. Thus, blood concentrations of six human essential metals and five toxic metals in 720 general populations from southeastern China were simultaneously determined as a measure of exposure. In addition, quantile g-computation, Bayesian kernel machine regression, elastic net regression, and generalized...
Source: Biological Trace Element Research - November 22, 2023 Category: Biology Authors: Guihua Du Xiaoguang Song Fankun Zhou Lu Ouyang Qi Li Shiying Ruan Rui Su Shaoqi Rao Yanhui Zhu Jie Xie Chang Feng Guangqin Fan Source Type: research

Effects of Zinc Supplementation on Inflammatory Status and Nonalcoholic Steatohepatitis in Overweight or Obese Children: a Randomized Clinical Trial
Biol Trace Elem Res. 2023 Nov 22. doi: 10.1007/s12011-023-03954-z. Online ahead of print.ABSTRACTThe purpose of the present clinical trial was to determine the impact of zinc supplementation on serum liver enzymes, steatosis severity, lipid profile, and inflammatory status in overweight or obese children with nonalcoholic steatohepatitis (NASH). This randomized controlled trial was conducted by enrolling 60 children with NASH, aged 10-18 years old. The participants were randomly assigned to two groups that received either 30 mg/day of elemental zinc or placebo for 16 weeks. The severity of liver steatosis was evaluated usi...
Source: Biological Trace Element Research - November 22, 2023 Category: Biology Authors: Vahidreza Ostadmohammadi Mohammad Javad Namazi Mahsa Rezasoltani Davood Kheirkhah Mohammad Rajabi Alireza Sharif Abbas Taghavi Ardakani Fariba Raygan Amelia A Assareh Mohammad Reza Sharif Source Type: research

Exploration of Toxic and Essential Metals in Popular Rice Grains of Bangladesh and Associated Human Health Risk Implications
Biol Trace Elem Res. 2023 Nov 22. doi: 10.1007/s12011-023-03962-z. Online ahead of print.ABSTRACTIn order to evaluate the benefits as well as the impacts of essential and toxic metals regarding human health, the six common rice grains (katarivhog, bashful, banglamoti, najirshail, branded miniket and loose miniket) were collected from four wholesale markets in Dhaka, the capital of Bangladesh, and were analyzed with different atomic absorption spectroscopy (AAS) techniques. The mean concentrations of the toxic metals Pb, Cd, Cr, and As had 0.299 ± 0.017, 0.157 ± 0.012, 1.33 ± 0.084, and 0.120 ± 0.006 mg/kg, respectively...
Source: Biological Trace Element Research - November 22, 2023 Category: Biology Authors: M Mozammal Hosen M Nur E Alam F S Tonni S R Khan M A Maksud L N Lutfa A K M Atique Ullah Rehena Begum Quamrun Nahar Shamshad B Quraishi Source Type: research

Effects of Dietary Selenium Yeast Supplementation on Oxidative Biomarkers of the Brain and Blood in Goats
Biol Trace Elem Res. 2023 Nov 22. doi: 10.1007/s12011-023-03966-9. Online ahead of print.ABSTRACTThe present study evaluated the effects of dietary selenium yeast (SY) on the brain, CSF, and blood of 30 crossbreed goats (5-6 months of age) of both sexes. After the acclimatization of 2 weeks, they were randomly separated into two groups (n = 15) named C and SY groups. The C group received only a basal diet, while SY received a basal diet along with 0.3 mg/kg/diet of SY (Sel-Plex®) in total 0.035 mg/kg/diet of SY for 10 weeks. Se concentration (µg /g dry weight) in 15 different parts of the goat's brain was accessed, and r...
Source: Biological Trace Element Research - November 22, 2023 Category: Biology Authors: Iqra Bano Moolchand Malhi Hira Sajjad Talpur Source Type: research

Association Between Multiple Metal(loid)s Exposure and Blood Lipid Levels: Evidence from a Cross-Sectional Study of Southeastern China
Biol Trace Elem Res. 2023 Nov 22. doi: 10.1007/s12011-023-03951-2. Online ahead of print.ABSTRACTExposure to essential and toxic metals occurs simultaneously as a mixture in real-life. However, there is no consensus regarding the effects of co-exposure to multiple metal(loid)s (designated hereafter metals) on blood lipid levels. Thus, blood concentrations of six human essential metals and five toxic metals in 720 general populations from southeastern China were simultaneously determined as a measure of exposure. In addition, quantile g-computation, Bayesian kernel machine regression, elastic net regression, and generalized...
Source: Biological Trace Element Research - November 22, 2023 Category: Biology Authors: Guihua Du Xiaoguang Song Fankun Zhou Lu Ouyang Qi Li Shiying Ruan Rui Su Shaoqi Rao Yanhui Zhu Jie Xie Chang Feng Guangqin Fan Source Type: research