Evaluation of Sanders Type 2 Joint Depression Calcaneal Fractures in 197 Patients from a Single Center Using Three-Dimensional Mapping
CONCLUSIONS The findings from this study showed that 3D CT imaging and reconstruction of the calcaneus was a useful diagnostic method to evaluate and classify joint depression calcaneal fractures. The calcaneal fracture map can be used to guide surgical planning and optimize the design of internal fixation.PMID:34294674 | DOI:10.12659/MSM.932748 (Source: Medical Science Monitor)
Source: Medical Science Monitor - July 23, 2021 Category: Research Authors: Xiaobo Guo Xiaonan Liang Jiangtao Jin Jinwei Chen Junyang Liu Jinming Zhao Source Type: research

Identification of Key Genes and Underlying Mechanisms in Acute Kawasaki Disease Based on Bioinformatics Analysis
CONCLUSIONS Our study identified the candidate genes and associated molecules that may be related to the KD process, and provided new insights into potential mechanisms and therapeutic targets for KD.PMID:34290221 | DOI:10.12659/MSM.930547 (Source: Medical Science Monitor)
Source: Medical Science Monitor - July 22, 2021 Category: Research Authors: Side Gao Wenjian Ma Xuze Lin Sizhuang Huang Mengyue Yu Source Type: research

Comparison of Intra-Abdominal Pressure Measurements in Critically Ill Patients Using Intravesical Normal Saline at 15 °C, 25°C, and 35°C
Med Sci Monit. 2021 Jul 21;27:e932804. doi: 10.12659/MSM.932804.ABSTRACTBACKGROUND The incidence of intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) in intensive care units is high. Dynamic monitoring of intra-abdominal pressure (IAP) is important to treat patients with these conditions. The World Society of Abdominal Compartment Syndrome revised IAP measurement and treatment guidelines in 2013. IAP is measured by instilling ≤25 mL of sterile saline into the bladder, but there is no requirement for the saline to be at a specific temperature. Many doctors presume that using cold saline will tri...
Source: Medical Science Monitor - July 21, 2021 Category: Research Authors: Jianfeng Zou Lili Zheng Weizheng Shuai Qi Li Qian Wang Zhicheng Zhang Dawei Li Source Type: research

Risk Prediction Model Based on Biomarkers of Remodeling in Patients with Acute Anterior ST-Segment Elevation Myocardial Infarction
Med Sci Monit. 2021 Jul 20;27:e927404. doi: 10.12659/MSM.927404.ABSTRACTBACKGROUND The aim of the present study was to develop a risk prediction model in patients with acute anterior ST-segment elevation myocardial infarction (STEMI). MATERIAL AND METHODS Clinical data from 333 patients with acute anterior STEMI were retrospectively analyzed. Clinical echocardiographic and angiographic data from patients with left ventricular remodeling (LVR) and those without LVR were compared. Factors that influenced risk were identified using multivariate logistic regression analysis. The area under the curve (AUC) of the receiver opera...
Source: Medical Science Monitor - July 20, 2021 Category: Research Authors: Zeyan Liu Lijun Liu Jinglin Cheng Hao Zhang Source Type: research

Editorial: Tocilizumab, a Humanized Therapeutic IL-6 Receptor (IL-6R) Monoclonal Antibody, and Future Combination Therapies for Severe COVID-19
Med Sci Monit. 2021 Jul 19;27:e933973. doi: 10.12659/MSM.933973.ABSTRACTVaccinated, non-vaccinated, and immunosuppressed individuals will continue to be infected with SARS-CoV-2. Therefore, there is a priority to develop treatments that reduce the severity of COVID-19 in patients who require hospital admission. Interleukin-6 (IL-6) is a proinflammatory cytokine. In 2011, a humanized monoclonal antibody to the IL-6 receptor (IL-6R), tocilizumab, was approved by the US Food and Drug Administration (FDA) for the treatment of rheumatoid arthritis, juvenile idiopathic arthritis, giant cell arteritis, and Castleman's disease. In...
Source: Medical Science Monitor - July 19, 2021 Category: Research Authors: Dinah V Parums Source Type: research

Comparison Between the Modified External Fixation and Calcaneal Traction in Ruedi-Allgower Type II/III Pilon Fractures
Med Sci Monit. 2021 Jul 19;27:e933385. doi: 10.12659/MSM.933385.ABSTRACTBACKGROUND To compare the effect of modified external fixation and calcaneal traction in a staged management of Ruedi-Allgower type II/III tibial pilon fractures. MATERIAL AND METHODS The data of 62 patients with Ruedi-Allgower type II/III tibial pilon fractures who were treated in Liuzhou People's hospital from January 2017 to December 2018 were extracted in this retrospective analysis. There were 32 patients in the temporary external fixation (TEF) group and 30 patients in calcaneal traction (CT) group. Outcomes, including the duration of the surgica...
Source: Medical Science Monitor - July 19, 2021 Category: Research Authors: Wen Shu Xiaodong Hu Xiaofan Yang Source Type: research

Editorial: Tocilizumab, a Humanized Therapeutic IL-6 Receptor (IL-6R) Monoclonal Antibody, and Future Combination Therapies for Severe COVID-19
Med Sci Monit. 2021 Jul 19;27:e933973. doi: 10.12659/MSM.933973.ABSTRACTVaccinated, non-vaccinated, and immunosuppressed individuals will continue to be infected with SARS-CoV-2. Therefore, there is a priority to develop treatments that reduce the severity of COVID-19 in patients who require hospital admission. Interleukin-6 (IL-6) is a proinflammatory cytokine. In 2011, a humanized monoclonal antibody to the IL-6 receptor (IL-6R), tocilizumab, was approved by the US Food and Drug Administration (FDA) for the treatment of rheumatoid arthritis, juvenile idiopathic arthritis, giant cell arteritis, and Castleman's disease. In...
Source: Medical Science Monitor - July 19, 2021 Category: Research Authors: Dinah V Parums Source Type: research

Comparison Between the Modified External Fixation and Calcaneal Traction in Ruedi-Allgower Type II/III Pilon Fractures
Med Sci Monit. 2021 Jul 19;27:e933385. doi: 10.12659/MSM.933385.ABSTRACTBACKGROUND To compare the effect of modified external fixation and calcaneal traction in a staged management of Ruedi-Allgower type II/III tibial pilon fractures. MATERIAL AND METHODS The data of 62 patients with Ruedi-Allgower type II/III tibial pilon fractures who were treated in Liuzhou People's hospital from January 2017 to December 2018 were extracted in this retrospective analysis. There were 32 patients in the temporary external fixation (TEF) group and 30 patients in calcaneal traction (CT) group. Outcomes, including the duration of the surgica...
Source: Medical Science Monitor - July 19, 2021 Category: Research Authors: Wen Shu Xiaodong Hu Xiaofan Yang Source Type: research

Interobserver Agreement in Semi-Quantitative Scale-Based Interpretation of Chest Radiographs in COVID-19 Patients
CONCLUSIONS The analyzed scales are characterized by good or very good interobserver agreement of assessments of the extent of pulmonary infiltration. Since the CXR Score showed the strongest correlation with the clinical condition of the patient as expressed using the MEWS scale, it is the preferred scale for chest radiograph assessment of patients with COVID-19 in the light of data provided.PMID:34274938 | DOI:10.12659/MSM.931277 (Source: Medical Science Monitor)
Source: Medical Science Monitor - July 18, 2021 Category: Research Authors: Bartosz Mruk Jerzy Walecki Piotr Gustaw Wasilewski Łukasz Paluch Katarzyna Sklinda Source Type: research

Time Perception is a Focal Symptom of Attention-Deficit/Hyperactivity Disorder in Adults
Med Sci Monit. 2021 Jul 17;27:e933766. doi: 10.12659/MSM.933766.ABSTRACTAttention-Deficit/Hyperactivity Disorder (ADHD) is classically associated with symptoms that include inattentiveness, hyperactivity, and impulsivity together with a variety of other observable externalized symptoms. ADHD has also been associated with specific internalized cognitive symptoms, including restlessness and emotional impulsivity. This disorder has been recognized as a lifelong condition and can be recognized by a variety of unique cognitive phenomena. In addition to the frequently ignored affective symptoms exhibited by individuals diagnosed...
Source: Medical Science Monitor - July 17, 2021 Category: Research Authors: Simon Weissenberger Katerina Schonova Pascal B üttiker Raffaele Fazio Martina Vnukova George B Stefano Radek Ptacek Source Type: research

lncRNA MEG3 Downregulation Relieves Intracerebral Hemorrhage by Inhibiting Oxidative Stress and Inflammation in an miR-181b-Dependent Manner
CONCLUSIONS MEG3-shRNA restrained oxidative stress and inflammation following ICH in an miR-181b-dependent manner.PMID:34267173 | DOI:10.12659/MSM.929435 (Source: Medical Science Monitor)
Source: Medical Science Monitor - July 16, 2021 Category: Research Authors: Bo Xie Mingliang Qiao Jialong Xuan Source Type: research

Epithelial Splicing Regulatory Protein 1 Is Overexpressed in Breast Cancer and Predicts Poor Prognosis for Breast Cancer Patients
CONCLUSIONS These results suggest that ESRP1 is a valuable target for the precise treatment of breast cancer and a potential biomarker for the prognosis of patients with breast cancer.PMID:34262011 | DOI:10.12659/MSM.931102 (Source: Medical Science Monitor)
Source: Medical Science Monitor - July 15, 2021 Category: Research Authors: Xinyu Liu Qiangshan Wang Siqi Song Manman Feng Xiaoya Wang Ling Li Ying Liu Chunying Shi Source Type: research

Low Dose of Emodin Inhibits Hypercholesterolemia in a Rat Model of High Cholesterol
CONCLUSIONS The ability of emodin to inhibit hypercholesterolemia in HCD-fed rats was associated with lower serum total-C and LDL-C, restoration of aortic endothelial function, and improved antioxidant capacity. Low-dose emodin showed better protection of aortic endothelium and better antioxidant activity than did higher doses.PMID:34257265 | DOI:10.12659/MSM.929346 (Source: Medical Science Monitor)
Source: Medical Science Monitor - July 14, 2021 Category: Research Authors: Jian-Hong Wu Chun-Fang Lv Xu-Jun Guo Huan Zhang Jinde Zhang Yangfeng Xu Jian Wang Sheng-Yuan Liu Source Type: research

Risk Factors for Fentanyl-Induced Cough Following General Anesthesia in Adults: A Retrospective Study from a Single Center in China
Med Sci Monit. 2021 Jul 13;27:e930369. doi: 10.12659/MSM.930369.ABSTRACTBACKGROUND Fentanyl-induced cough (FIC) during general anesthesia induction and postoperative nausea and vomiting are common complications, yet the risk factors for FIC remain controversial. This retrospective study was conducted at a single center in China and aimed to investigate the risk factors for fentanyl-induced cough following general anesthesia in adults. MATERIAL AND METHODS A total of 601 adult patients undergoing elective surgery were enrolled, and the incidence of FIC during general anesthesia induction and postoperative adverse events wer...
Source: Medical Science Monitor - July 13, 2021 Category: Research Authors: Xiao Zhao Hong Wang Hui-Juan Wang Yun Wang Yi-An Xing Shi-Tong Li Lian-Hua Chen Source Type: research

Editorial: International Consensus Recommendations to Replace the Terminology of Non-Alcoholic Fatty Liver Disease (NAFLD) with Metabolic-Associated Fatty Liver Disease (MAFLD)
Med Sci Monit. 2021 Jul 12;27:e933860. doi: 10.12659/MSM.933860.ABSTRACTIn 2020, international consensus guidelines recommended the renaming of non-alcoholic fatty liver disease (NAFLD) to metabolic-associated fatty liver disease (MAFLD), supported by diagnostic criteria. MAFLD affects up to 25% of the global population. However, the rates of MAFLD are likely to be underestimated due to the increasing prevalence of type 2 diabetes mellitus (T2DM) and obesity. Within the next decade, MAFLD has been projected to become a major cause of cirrhosis and hepatocellular carcinoma (HCC) worldwide, as well as the most common indicat...
Source: Medical Science Monitor - July 12, 2021 Category: Research Authors: Nahum M éndez-Sánchez Luis Enrique D íaz-Orozco Source Type: research

Characteristics and Related Factors of High-Risk Human Papillomavirus Infection in Pregnant Women
Med Sci Monit. 2021 Jul 12;27:e929100. doi: 10.12659/MSM.929100.ABSTRACTBACKGROUND Cervical cancer is a risk for women worldwide. The aim of this study was to examine the occurrence of high-risk human papillomavirus (HR-HPV) infection and its related factors in pregnant women and provide a scientific basis for the targeted prevention and treatment of cervical cancer in pregnant women. MATERIAL AND METHODS A total of 1774 pregnant women were included, and 1774 non-pregnant women were selected as controls. Cervical exfoliated cells were collected from all women for HR-HPV (AptimaE6, E7mRNA) and ThinPrep cytologic testing, an...
Source: Medical Science Monitor - July 12, 2021 Category: Research Authors: Yingying Chen Jie Dong Boliang Chu Xiaoxing Zhang Xiaofang Ru Yun Chen Yunyan Chen Xiaodong Cheng Source Type: research

Editorial: International Consensus Recommendations to Replace the Terminology of Non-Alcoholic Fatty Liver Disease (NAFLD) with Metabolic-Associated Fatty Liver Disease (MAFLD)
Med Sci Monit. 2021 Jul 12;27:e933860. doi: 10.12659/MSM.933860.ABSTRACTIn 2020, international consensus guidelines recommended the renaming of non-alcoholic fatty liver disease (NAFLD) to metabolic-associated fatty liver disease (MAFLD), supported by diagnostic criteria. MAFLD affects up to 25% of the global population. However, the rates of MAFLD are likely to be underestimated due to the increasing prevalence of type 2 diabetes mellitus (T2DM) and obesity. Within the next decade, MAFLD has been projected to become a major cause of cirrhosis and hepatocellular carcinoma (HCC) worldwide, as well as the most common indicat...
Source: Medical Science Monitor - July 12, 2021 Category: Research Authors: Nahum M éndez-Sánchez Luis Enrique D íaz-Orozco Source Type: research

Characteristics and Related Factors of High-Risk Human Papillomavirus Infection in Pregnant Women
Med Sci Monit. 2021 Jul 12;27:e929100. doi: 10.12659/MSM.929100.ABSTRACTBACKGROUND Cervical cancer is a risk for women worldwide. The aim of this study was to examine the occurrence of high-risk human papillomavirus (HR-HPV) infection and its related factors in pregnant women and provide a scientific basis for the targeted prevention and treatment of cervical cancer in pregnant women. MATERIAL AND METHODS A total of 1774 pregnant women were included, and 1774 non-pregnant women were selected as controls. Cervical exfoliated cells were collected from all women for HR-HPV (AptimaE6, E7mRNA) and ThinPrep cytologic testing, an...
Source: Medical Science Monitor - July 12, 2021 Category: Research Authors: Yingying Chen Jie Dong Boliang Chu Xiaoxing Zhang Xiaofang Ru Yun Chen Yunyan Chen Xiaodong Cheng Source Type: research

Identification of CXCL13 as an Immune-Related Biomarker Associated with Tumorigenesis and Prognosis in Cutaneous Melanoma Patients
CONCLUSIONS This study found that CXCL13 is associated with SKCM tumorigenesis and prognosis and immune infiltrations. Our result suggests that CXCL13 has great potential in development of novel immunotherapy targets in melanoma.PMID:34247183 | DOI:10.12659/MSM.932052 (Source: Medical Science Monitor)
Source: Medical Science Monitor - July 11, 2021 Category: Research Authors: Zebing Si Honghe Hu Source Type: research

Outcomes of Targeted Temperature Management for In-Hospital and Out-Of-Hospital Cardiac Arrest: A Matched Case-Control Study Using the National Database of Taiwan Network of Targeted Temperature Management for Cardiac Arrest (TIMECARD) Registry
CONCLUSIONS The findings from the national TIMECARD registry showed that clinical outcomes following TTM for patients with IHCA were not significantly different from OHCA when baseline factors were matched.PMID:34244465 | DOI:10.12659/MSM.931203 (Source: Medical Science Monitor)
Source: Medical Science Monitor - July 10, 2021 Category: Research Authors: Yu-San Chien Min-Shan Tsai Chien-Hua Huang Chih-Hung Lai Wei-Chun Huang Lung Chan Li-Kuo Kuo Source Type: research

Secondary Immunodeficiency and Hypogammaglobulinemia with IgG Levels of & lt;5 g/L in Patients with Multiple Myeloma: A Retrospective Study Between 2012 and 2020 at a University Hospital in China
Med Sci Monit. 2021 Jul 9;27:e930241. doi: 10.12659/MSM.930241.ABSTRACTBACKGROUND Infections are the main cause of mortality and morbidity in multiple myeloma (MM) patients. However, adult immunodeficiency specialists in China are lacking, and the care of secondary immunodeficiency (SID) and the prognostic role of hypogammaglobulinemia in MM is unknown. MATERIAL AND METHODS MM patients (295) were retrospectively analyzed between January 2012 and 2020 in Zhejiang Provincial People's Hospital, Hangzhou Medical College. MM patients with immunoglobulin (Ig) G
Source: Medical Science Monitor - July 9, 2021 Category: Research Authors: Chunmei Ye Weiwei Chen Qi Gao Yanxia Chen Xiaolu Song Sujie Zheng Jinlin Liu Source Type: research

Transurethral Microwave Thermotherapy (TUMT) in the Treatment of Benign Prostatic Hyperplasia: A Preliminary Report
Med Sci Monit. 2021 Jul 8;27:e931597. doi: 10.12659/MSM.931597.ABSTRACTBACKGROUND One treatment option for benign prostatic hyperplasia (BPH) is transurethral microwave thermotherapy (TUMT). Unfortunately, TUMT has been increasingly marginalized recently. The aim of this study was to evaluate erectile function and urinary symptoms in patients after TUMT for BPH and compare the results with those of patients on pharmacological treatment for BPH. MATERIAL AND METHODS The study group consisted of 840 patients with BPH treated with TUMT and a control group consisting of 1040 patients who underwent pharmacotherapy. Erectile dys...
Source: Medical Science Monitor - July 8, 2021 Category: Research Authors: Roger J Zi ętek Zbigniew M Zi ętek Source Type: research

Application of the RCOG Risk Assessment Model for Evaluating Postpartum Venous Thromboembolism in Chinese Women: A Case-Control Study
CONCLUSIONS The RCOG RAM was found to be effective in predicting postpartum VTE, and has certain guiding significance for postpartum thromboprophylaxis in China.PMID:34230447 | DOI:10.12659/MSM.929904 (Source: Medical Science Monitor)
Source: Medical Science Monitor - July 7, 2021 Category: Research Authors: Ying-Zhou Ge Chen Zhang Yan-Qing Cai He-Feng Huang Source Type: research

Independent Risk Factors of Postoperative Lymphatic Leakage in Patients with Gynecological Malignant Tumor: A Single-Center Retrospective Study
Med Sci Monit. 2021 Jul 6;27:e932678. doi: 10.12659/MSM.932678.ABSTRACTBACKGROUND We aimed this investigation to screen and analyze the risk factors of postoperative lymphatic leakage of gynecological malignant tumors that contribute to the treatment of the diseases. MATERIAL AND METHODS According to the occurrence of lymphatic leakage after an operation, 655 patients with pelvic lymph node and/or abdominal para-aortic lymph node dissection for gynecological malignant tumor were retrospectively analyzed and divided into a case group and a control group. Univariate and multivariate logistic regression analysis were used to ...
Source: Medical Science Monitor - July 6, 2021 Category: Research Authors: Min Du Lei Wang Liyun Zhao Wei Huang Xiaoling Fang Xiaomeng Xia Source Type: research

Identification and Characterization of Non-Coding RNAs in Thymoma
CONCLUSIONS Our results show that overexpression of this miRNA cluster activates PI3K-Akt, FoxO, HIF-1, and Rap-1 signaling pathways, suggesting pathway inhibitors may be therapeutic candidates against thymoma.PMID:34219124 | DOI:10.12659/MSM.929727 (Source: Medical Science Monitor)
Source: Medical Science Monitor - July 5, 2021 Category: Research Authors: Guanglei Ji Rongrong Ren Xichao Fang Source Type: research

Editorial: Maternal SARS-CoV-2 Infection and Pregnancy Outcomes from Current Global Study Data
Med Sci Monit. 2021 Jul 5;27:e933831. doi: 10.12659/MSM.933831.ABSTRACTDuring the global COVID-19 pandemic, data from clinical studies, systematic review, and population registry data have shown that when compared with non-pregnant women, SARS-CoV-2 infection in pregnancy is associated with a small increase in risk to the mother. Large cohort studies and registry data collected from 2020 have included the US Surveillance for Emerging Threats to Mothers and Babies Network (SET-NET), COVI-PREG, the UK and Global Pregnancy and Neonatal Outcomes in COVID-19 (PAN-COVID) study, the American Academy of Pediatrics (AAP) Section on...
Source: Medical Science Monitor - July 5, 2021 Category: Research Authors: Dinah V Parums Source Type: research

Identification and Characterization of Non-Coding RNAs in Thymoma
CONCLUSIONS Our results show that overexpression of this miRNA cluster activates PI3K-Akt, FoxO, HIF-1, and Rap-1 signaling pathways, suggesting pathway inhibitors may be therapeutic candidates against thymoma.PMID:34219124 | DOI:10.12659/MSM.929727 (Source: Medical Science Monitor)
Source: Medical Science Monitor - July 5, 2021 Category: Research Authors: Guanglei Ji Rongrong Ren Xichao Fang Source Type: research

Editorial: Maternal SARS-CoV-2 Infection and Pregnancy Outcomes from Current Global Study Data
Med Sci Monit. 2021 Jul 5;27:e933831. doi: 10.12659/MSM.933831.ABSTRACTDuring the global COVID-19 pandemic, data from clinical studies, systematic review, and population registry data have shown that when compared with non-pregnant women, SARS-CoV-2 infection in pregnancy is associated with a small increase in risk to the mother. Large cohort studies and registry data collected from 2020 have included the US Surveillance for Emerging Threats to Mothers and Babies Network (SET-NET), COVI-PREG, the UK and Global Pregnancy and Neonatal Outcomes in COVID-19 (PAN-COVID) study, the American Academy of Pediatrics (AAP) Section on...
Source: Medical Science Monitor - July 5, 2021 Category: Research Authors: Dinah V Parums Source Type: research

Impact of Gentamicin-Impregnated Collagen on the Intra-Abdominal Adhesions and Integrity of Colonic Anastomosis: An Experimental Study
CONCLUSIONS This study suggests that colo-colonic anastomosis coverage using materials incorporating collagen alone or gentamicin-impregnated collagen increases the safety of anastomosis and reduces intra-abdominal adhesions.PMID:34218250 | DOI:10.12659/MSM.931959 (Source: Medical Science Monitor)
Source: Medical Science Monitor - July 4, 2021 Category: Research Authors: Esin Ert ürer Oruç Do ğan Albayrak Source Type: research

Factors Associated with the Prognosis of Patients with Acute Myocardial Infarction and Cardiogenic Shock
This study aimed to identify factors related to the short-term survival of patients with AMI and CS treated by percutaneous coronary intervention (PCI) under intra-aortic balloon pump (IABP) support. MATERIAL AND METHODS This retrospective study included consecutive patients with AMI and CS treated with PCI under IABP support. Clinical characteristics, including the infarct-related artery, lesion number, aspiration catheter usage, conventional or delayed stenting, and thrombolysis in myocardial infarction (TIMI) flow grade before and after PCI, were collected. Patients were followed up postoperatively for 30 days. Multivar...
Source: Medical Science Monitor - July 3, 2021 Category: Research Authors: Ke-Fu Feng Min Wu Li-Kun Ma Source Type: research

Exploration of the Important Role of Microfibril-Associated Protein 4 Gene in Oral Squamous Cell Carcinoma
CONCLUSIONS Our work provides evidence that expression of MFAP4 can be used as a prognostic biomarker for risk stratification of OSCC patients and elaborates on its relation with the regulation of TMB, miRNAs, and immune cell infiltration.PMID:34210950 | DOI:10.12659/MSM.931238 (Source: Medical Science Monitor)
Source: Medical Science Monitor - July 2, 2021 Category: Research Authors: Ying Han Kun Xia Tong Su Source Type: research

Effects of Infection with SARS-CoV-2 on the Male and Female Reproductive Systems: A Review
Med Sci Monit. 2021 Jul 1;27:e930168. doi: 10.12659/MSM.930168.ABSTRACTCoronavirus Disease-2019 (COVID-19) is a rapidly spreading pandemic that began at the end of 2019. COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Reproductive health has always been one of the most important healthcare problems, and the impacts of COVID-19 on the reproductive systems have become an emerging topic. The effects of infection with SARS-CoV-2 on males are more harmful than on females. The outcomes of pregnancy also can show the condition of male and female reproductive system health. The vertical transmis...
Source: Medical Science Monitor - July 1, 2021 Category: Research Authors: Chunlian Liu Chunlan Mu Qian Zhang Xiwen Yang Hui Yan Haiyan Jiao Source Type: research

An Investigation of Mental Health Status Among Medical Staff Following COVID-19 Outbreaks: A Cross-Sectional Study
This study was to investigate the situation of mental health status among medical staff following COVID-19. MATERIAL AND METHODS A cross-sectional study was conducted through structured questionnaires to collect the demographical information of the participating medical staff via WeChat following COVID-19 crisis. The Center for Epidemiologic Studies-Depression Scale (CES-D), impact of events scale revised (IES-R), and Pittsburgh Sleep Quality Index (PSQI) scale were used to evaluate depression, post-traumatic stress disorder (PTSD) symptoms, and sleep quality, respectively. 95% confidence intervals (CI) were calculated. RE...
Source: Medical Science Monitor - June 30, 2021 Category: Research Authors: Liwen Chen Dongmei Lin Haishan Feng Source Type: research

Relationship of Bone Status with Serum Uric Acid and Bilirubin in Men with Type 2 Diabetes: A Cross-Sectional Study
This study was designed to assess the relationship of serum uric acid and total bilirubin with bone mineral density and bone turnover markers in men with type 2 diabetes. MATERIAL AND METHODS In total, 631 male patients with type 2 diabetes were included. Data of patients' medical history, biochemical index, bone mineral density of the lumbar vertebra, femoral neck, and total hip, and bone turnover markers including osteocalcin (OC), amino-terminal propeptide of type I procollagen (PINP), type I collagen carboxy-terminal peptide (CTX), and parathyroid hormone were collected and retrospectively analyzed. RESULTS Both serum ...
Source: Medical Science Monitor - June 29, 2021 Category: Research Authors: Yang Wu Shoukui Xiang Xiaohong Jiang Long Wang Kun Wang Fei Hua Source Type: research

Intermittent Theta Burst Stimulation (iTBS) for Treatment of Chronic Post-Stroke Aphasia: Results of a Pilot Randomized, Double-Blind, Sham-Controlled Trial
Med Sci Monit. 2021 Jun 29;27:e931468. doi: 10.12659/MSM.931468.ABSTRACTBACKGROUND Research indicates intermittent theta burst stimulation (iTBS) is a potential treatment of post-stroke aphasia. MATERIAL AND METHODS In this double-blind, sham-controlled trial (NCT01512264) participants were randomized to receive 3 weeks of sham (G₀), 1 week of iTBS/2 weeks of sham (G₁), 2 weeks of iTBS/1 week of sham (G₂), or 3 weeks of iTBS (G₃). FMRI localized residual language function in the left hemisphere; iTBS was applied to the maximum fMRI activation in the residual language cortex in the left frontal lobe. FMRI and aphasi...
Source: Medical Science Monitor - June 29, 2021 Category: Research Authors: Jerzy P Szaflarski Rodolphe Nenert Jane B Allendorfer Amber N Martin Amy W Amara Joseph C Griffis Aimee Dietz Victor W Mark Victor W Sung Harrison C Walker Xiaohua Zhou Christopher J Lindsell Source Type: research

Relationship of Bone Status with Serum Uric Acid and Bilirubin in Men with Type 2 Diabetes: A Cross-Sectional Study
This study was designed to assess the relationship of serum uric acid and total bilirubin with bone mineral density and bone turnover markers in men with type 2 diabetes. MATERIAL AND METHODS In total, 631 male patients with type 2 diabetes were included. Data of patients' medical history, biochemical index, bone mineral density of the lumbar vertebra, femoral neck, and total hip, and bone turnover markers including osteocalcin (OC), amino-terminal propeptide of type I procollagen (PINP), type I collagen carboxy-terminal peptide (CTX), and parathyroid hormone were collected and retrospectively analyzed. RESULTS Both serum ...
Source: Medical Science Monitor - June 29, 2021 Category: Research Authors: Yang Wu Shoukui Xiang Xiaohong Jiang Long Wang Kun Wang Fei Hua Source Type: research

Intermittent Theta Burst Stimulation (iTBS) for Treatment of Chronic Post-Stroke Aphasia: Results of a Pilot Randomized, Double-Blind, Sham-Controlled Trial
Med Sci Monit. 2021 Jun 29;27:e931468. doi: 10.12659/MSM.931468.ABSTRACTBACKGROUND Research indicates intermittent theta burst stimulation (iTBS) is a potential treatment of post-stroke aphasia. MATERIAL AND METHODS In this double-blind, sham-controlled trial (NCT01512264) participants were randomized to receive 3 weeks of sham (G₀), 1 week of iTBS/2 weeks of sham (G₁), 2 weeks of iTBS/1 week of sham (G₂), or 3 weeks of iTBS (G₃). FMRI localized residual language function in the left hemisphere; iTBS was applied to the maximum fMRI activation in the residual language cortex in the left frontal lobe. FMRI and aphasi...
Source: Medical Science Monitor - June 29, 2021 Category: Research Authors: Jerzy P Szaflarski Rodolphe Nenert Jane B Allendorfer Amber N Martin Amy W Amara Joseph C Griffis Aimee Dietz Victor W Mark Victor W Sung Harrison C Walker Xiaohua Zhou Christopher J Lindsell Source Type: research