Sudden Death from Ischemic Heart Disease While Driving: Cardiac Pathology, Clinical Characteristics, and Countermeasures.
CONCLUSIONS Regular physical examination and information about ischemic heart disease should be emphasized for men aged 40 to 60 years who drive frequently, especially for those with hypertension, overwork, or previous myocardial infarction. Incorporating objective evaluation criteria for the severity of ischemic heart disease and overwork into health condition-related driving regulations is needed. PMID: 33495433 [PubMed - in process] (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 28, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Predictive Value of a Thyroid-Absorbed Dose with a Shorter Effective Half-Life on Efficacy in Graves Disease Patients Receiving Iodine-131 Therapy.
CONCLUSIONS Predicting RIT efficacy from TD with a shorter Teff was feasible in GD patients, and TD above 70.2 Gy had an especially high predictive accuracy. PMID: 33497370 [PubMed - in process] (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 28, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Elevated Plasma Angiopoietinlike Protein 5 (ANGPTL5) Is More Positively Associated with Glucose Metabolism Disorders in Patients with Metabolic Syndrome.
Authors: Liu C, Yi X, Lyu Y, Ren W, Zhou Y, Feng G, Wan W, Jiang XJ Abstract BACKGROUND Angiopoietinlike protein 5 (ANGPTL5) is an adipocytokine and has an important role in metabolic processes including lipid metabolism, obesity, and type 2 diabetes mellitus. On the basis of these roles, the present study aimed to investigate the level and role of plasma ANGPTL5 in metabolic syndrome (MS) patients. MATERIAL AND METHODS A total of 139 participants was enrolled in this study; 69 of them were diagnosed with MS. Plasma ANGPTL5 levels were measured by enzyme-linked immunosorbent assay. Sex, age, and other laboratory te...
Source: Medical Science Monitor - January 26, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Selective Neuronal Mitochondrial Targeting in SARS-CoV-2 Infection Affects Cognitive Processes to Induce 'Brain Fog' and Results in Behavioral Changes that Favor Viral Survival.
Authors: Stefano GB, Ptacek R, Ptackova H, Martin A, Kream RM Abstract Alterations in brain functioning, especially in regions associated with cognition, can result from infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and are predicted to result in various psychiatric diseases. Recent studies have shown that SARS-CoV-2 infection and coronavirus disease 2019 (COVID-19) can directly or indirectly affect the central nervous system (CNS). Therefore, diseases associated with sequelae of COVID-19, or 'long COVID', also include serious long-term mental and cognitive changes, including the condi...
Source: Medical Science Monitor - January 26, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Bronchiolitis Associated with Mycoplasma pneumoniae Infection in Infants in Foshan China: An Epidemiologic Study.
Authors: Chen C, Lin C, Zhong X, Wen D, Zhang J Abstract BACKGROUND Bronchiolitis is common in infants under 2 years of age. Most infections are caused by respiratory syncytial virus (RSV), but the importance of Mycoplasma pneumoniae (MP) in the etiology of bronchiolitis is unclear. MATERIAL AND METHODS We investigated the clinical characteristics of bronchiolitis caused by MP in 79 infants admitted to Shunde Women's and Children's Hospital of Guangdong Medical University and Sanshui Women's and Children's Healthcare Hospital from January 2016 to December 2018. Infection with MP was confirmed by the presence of ser...
Source: Medical Science Monitor - January 26, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Correlation Between High Expression of FOXA2 and Improved Overall Survival in Ovarian Cancer Patients.
Authors: Shang H, Shi L, Jiang X, Zhou P, Wei Y Abstract BACKGROUND The aim of the present work was to evaluate FOXA2 expression in ovarian cancer and to use integrated bioinformatics analysis to correlate it with patient prognosis. MATERIAL AND METHODS FOXA2 expression was evaluated in multiple cancers in The Cancer Genome Atlas database. A protein-protein interaction (PPI) network relevant to FOXA2 was constructed using the Search Tool for Retrieval of Interacting Genes/Proteins (STRIN). Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analyses were performed of FOXA2 and relevant gene...
Source: Medical Science Monitor - January 25, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Association Between Formative Assessment and Academic Performance for Undergraduate Medical Students in a Chinese Clinical Skills Training Course.
CONCLUSIONS Proper use of FA is associated with better learning outcomes for students, especially for those with poorer grades. Our results, together with previous research, indicated that the use of FA may be of great benefit to students' academic performance and satisfaction with the clinical skills training curriculum. PMID: 33484506 [PubMed - as supplied by publisher] (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 25, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Cross-Cultural Adaptation and Validation of the Musculoskeletal Pain Intensity and Interference Questionnaire for Musicians of the Polish Population (MPIIQM-P).
CONCLUSIONS Translation and a cross-cultural adaptation of the Polish version of the questionnaire was successfully completed. The results obtained show a correctly carried-out validation process, but further testing of the tool is suggested. The Polish-language version of the validated tool can be used in scientific and clinical practice. The next step would be to estimate cutoff values for severity of health status in orchestra musicians. PMID: 33479189 [PubMed - in process] (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 23, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Evaluation of Demineralized Bone Matrix Particles Delivered by Alginate Hydrogel for a Bone Graft Substitute: An Animal Experimental Study.
CONCLUSIONS The delivery of DBM particles using a synthetic alginate hydrogel carrier may be a promising approach in bone tissue engineering for bone defects. PMID: 33481770 [PubMed - as supplied by publisher] (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 23, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Association Between Mitochondrial DNA Copy Number and Head and Neck Squamous Cell Carcinoma: A Systematic Review and Dose-Response Meta-Analysis.
Authors: Zhu Z, Liu Y, Wu D, Wang H Abstract BACKGROUND The association between mitochondrial DNA (mtDNA) copy number and head and neck squamous cell carcinoma (HNSCC) risk remains unclear. Therefore, we aimed to evaluate the relationship between mtDNA copy number and HNSCC risk. MATERIAL AND METHODS We searched PubMed, Web of Science, and EMBASE until August 2020. Studies that assessed the association between mtDNA copy number and HNSCC as the outcome of interest were included. We performed a 2-class and dose-response meta-analysis to assess the association between cancer risk and mtDNA. RESULTS Eight articles (2 ...
Source: Medical Science Monitor - January 22, 2021 Category: Research Tags: Med Sci Monit Source Type: research

A Novel RNA-Binding Protein-Based Nomogram for Predicting Survival of Patients with Gastric Cancer.
CONCLUSIONS Our study provides a nomogram model that consists of age and a 15-RBP signature and identifies 2 molecular subtypes for gastric cancer that possess potential value for preclinical, clinical, and translational research on gastric cancer. PMID: 33471782 [PubMed - in process] (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 22, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Retracted: Pleuromutilin Inhibits Proliferation and Migration of A2780 and Caov-3 Ovarian Carcinoma Cells and Growth of Mouse A2780 Tumor Xenografts by Down-Regulation of pFAK2.
Authors: Zhang B, Ma X, Li Y, Li S, Cheng J Abstract Some cells or groups of cells in figures appear to be visible multiple times. Because the manuscript contains non-credible results this journal is retracting the above publication. Reference: Bo Zhang, Xiaoli Ma, Yuan Li, Sijing Li, Jiumei Cheng: Pleuromutilin Inhibits Proliferation and Migration of A2780 and Caov-3 Ovarian Carcinoma Cells and Growth of Mouse A2780 Tumor Xenografts by Down-Regulation of pFAK2. Med Sci Monit, 2020; 26: e920407. DOI: 10.12659/MSM.920704. PMID: 33473098 [PubMed - in process] (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 22, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Norepinephrine, Dopamine, and Vasopressin in Patients with Sepsis and Preexisting or Acute Heart Failure: A Retrospective Cohort Study.
Authors: Zhou D, Zhu B, Jiang J, Zhou G, Zhou S Abstract BACKGROUND The aim of this study was to assess the impact of norepinephrine (NE), norepinephrine plus vasopressin (NE+VAS) and dopamine in patients with sepsis and heart failure. MATERIAL AND METHODS Data were extracted from the Medical Information Mart for Intensive Care III database, v1.4. Adults aged>18 years in an Intensive Care Unit (ICU) who had heart failure and took vasopressors were included. The patients were divided into 3 groups: NE, NE+VAS, and dopamine. Differences in survival, treatment time, and organ function among the 3 groups were compar...
Source: Medical Science Monitor - January 22, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Effect of Lung Recruitment Maneuvers on Reduction of Atelectasis Determined by Lung Ultrasound in Patients More Than 60 Years Old Undergoing Laparoscopic Surgery for Colorectal Carcinoma: A Prospective Study at a Single Center.
Authors: Yang Y, Geng Y, Zhang D, Wan Y, Wang R Abstract BACKGROUND Atelectasis occurs in patients of all ages during various surgeries. Previous studies have mainly focused on perioperative atelectasis in infants. However, research on the incidence of atelectasis among elderly patients, particularly those undergoing laparoscopic surgeries, is limited. Therefore, this prospective study aimed to investigate the effect of lung recruitment maneuvers (LRMs) on the reduction of atelectasis determined by lung ultrasound in patients more than 60 years old undergoing laparoscopic surgery for colorectal carcinoma. MATERIAL ...
Source: Medical Science Monitor - January 21, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Urinary Alpha1-Microglobulin: A New Predictor for In-Hospital Mortality in Patients with ST-Segment Elevation Myocardial Infarction.
Authors: Cui H, Zhang X, Ding X, Zhou L, Liang S, Qiu H, Li H, Chen H Abstract BACKGROUND Alpha1-microglobulin (A1MG) is a small molecular protein related to oxidation and inflammation. It exists in diverse body fluids, including urine. Results from urine tests are sometimes neglected when predicting in-hospital prognosis. It remains unclear whether urinary A1MG (UA1MG) can predict short-term prognosis of ST-elevated myocardial infarction (STEMI). MATERIAL AND METHODS A total of 1854 hospitalized patients with acute STEMI were retrospectively enrolled in our study. Medical records were used to obtain patient demogr...
Source: Medical Science Monitor - January 21, 2021 Category: Research Tags: Med Sci Monit Source Type: research

The Smart Class Teaching Module for Rehabilitation Medicine English Education in China.
Authors: Lin Q, Qiu Y, Liang J, Zheng Y, Liao Y, Huang H, Hou L, Lang S, Zhao B, Yiming Z, Yan Q, Ou H, Zhang Y Abstract BACKGROUND Learning medical English is particularly challenging for non-native English-speaking medical students. The Smart Class teaching module is a new online teaching module for rehabilitation-related medical English, the efficacy of which has yet to be established in the literature. Gender differences should also not be ignored in our study, taking into account the proven performance differences between males and females in language learning. MATERIAL AND METHODS First-year physiotherapy stu...
Source: Medical Science Monitor - January 21, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Bioinformatics Analysis of Differentially Expressed Genes and Protein-Protein Interaction Networks Associated with Functional Pathways in Ulcerative Colitis.
CONCLUSIONS Bioinformatics analysis using 3 GEO datasets identified CXCL8, CXCL1, and IL-1ß, which are involved in IL-10 signaling, as the top 3 hub genes in ulcerative colitis. The findings from this study remain to be validated, but they may contribute to the further understanding of the pathogenesis of ulcerative colitis. PMID: 33462173 [PubMed - in process] (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 21, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Subtypes of Influenza Virus Infection and Outcomes in Individuals Older than 65 Years of Age in Poland in the 2016/2017 to 2019/2020 Epidemic Seasons.
CONCLUSIONS This population study showed that, in Poland, between the 2016/2017 and 2019/2020 epidemic seasons, people who were more than 65 years of age were at higher risk of influenza virus infection and its complications. The findings support the importance of seasonal influenza vaccination in the population over age 65 years. PMID: 33465057 [PubMed - in process] (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 21, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Retracted: Ursolic Acid Exhibits Potent Anticancer Effects in Human Metastatic Melanoma Cancer Cells (SK-MEL-24) via Apoptosis Induction, Inhibition of Cell Migration and Invasion, Cell Cycle Arrest, and Inhibition of Mitogen-Activated Protein Kinase (MAPK)/ERK Signaling Pathway.
Authors: Liu P, Du R, Yu X Abstract Retraction of this publication has been requested by the authors due to problems with reproducibility. Reference: Pengcheng Liu, Ruili Du, Xin Yu. Ursolic Acid Exhibits Potent Anticancer Effects in Human Metastatic Melanoma Cancer Cells (SK-MEL-24) via Apoptosis Induction, Inhibition of Cell Migration and Invasion, Cell Cycle Arrest, and Inhibition of Mitogen-Activated Protein Kinase (MAPK)/ERK Signaling Pathway Med Sci Monit 2019; 25:1283-1290. 10.12659/MSM.913069. PMID: 33452230 [PubMed - as supplied by publisher] (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 18, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Evaluation of 3-Dimensional Magnetic Resonance Imaging (3D MRI) in Diagnosing Anterior Talofibular Ligament Injury.
This study aimed to evaluate the accuracy of 3D MRI and compare it with 2D MRI in diagnosing ATFL injury. MATERIAL AND METHODS This was a prospective study in which 45 patients with clinically suspected ATFL injury underwent 2D MRI, 3D MRI, and 3D model reconstruction followed by arthroscopic surgery between February 2018 and April 2019. Two radiologists who had over 11 and 13 years of musculoskeletal experience assessed the injury of ATFL in consensus without any clinical clues. Arthroscopic surgery results were the standard reference of MRI accuracy. RESULTS The 3D MRI results of ATFL injury showed the sensitivity of dia...
Source: Medical Science Monitor - January 18, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Comparison of Rocuronium with Succinylcholine for Rapid Sequence Induction Intubation in the Emergency Department: A Retrospective Study at a Single Center in China.
CONCLUSIONS The findings from this study support results from previous studies, showing that even in the Emergency Department setting, rocuronium was equivalent to succinylcholine in achieving rapid sequence induction intubation, when the dose was appropriate. However, as current clinical guidelines highlight, succinylcholine has more contraindications and adverse effects, including hyperkalemia, which should be monitored, and rocuronium has a longer duration of action. PMID: 33441534 [PubMed - in process] (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 16, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Mechanical Stress Affects Circadian Rhythm in Skeletal Muscle (C2C12 Myoblasts) by Reducing Per/Cry Gene Expression and Increasing Bmal1 Gene Expression.
CONCLUSIONS Our study revealed that mechanical stress loading affected circadian rhythm in skeletal muscle (C2C12 myoblasts) through reducing Per/Cry and enhancing Clock/Bmal1 gene expression. This study provides insights for investigating circadian rhythm and associated bio-functions of humans. PMID: 33444293 [PubMed - in process] (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 16, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Alterations in Cerebral Hemodynamics During Microgravity: A Literature Review.
Authors: Du J, Cui J, Yang J, Wang P, Zhang L, Luo B, Han B Abstract Most reported neurological symptoms that happen after exposure to microgravity could be originated from alterations in cerebral hemodynamics. The complicated mechanisms involved in the process of hemodynamics and the disparate experimental protocols designed to study the process may have contributed to the discrepancies in results between studies and the lack of consensus among researchers. This literature review examines spaceflight and ground-based studies of cerebral hemodynamics and aims to summarize the underlying physiological mechanisms tha...
Source: Medical Science Monitor - January 16, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Wide-Field Fluorescein Angiography in the Diagnosis and Management of Retinal Vein Occlusion: A Retrospective Single-Center Study.
CONCLUSIONS Decision-making about management of patients with RVO should be done after physical examination and analysis of central and peripheral retina FA. In 20.6% of patients, assessment of the peripheral retina resulted in a change in treatment. The first changes suggestive of progression of thrombotic disease to the ischemic form appeared on the periphery in images from WF-FA. PMID: 33449920 [PubMed - as supplied by publisher] (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 16, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Systems Pharmacology-Based Identification of Mechanisms of Action of Bolbostemma paniculatum for the Treatment of Hepatocellular Carcinoma.
CONCLUSIONS The PI3K/Akt, HIF1, p53, and PPAR pathways may play vital roles in TBM treatment of HCC. Also, the potential anti-cancer effect of TBM on HCC appears to stem from the synergetic effect of multiple targets and mechanisms. PMID: 33436534 [PubMed - in process] (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 15, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Analysis of Root Canal Curvature and Root Canal Morphology of Maxillary Posterior Teeth in Guizhou, China.
Authors: Qiao X, Xu T, Chen L, Yang D Abstract BACKGROUND We investigated the root canal curvature and morphology of maxillary posterior teeth in Guizhou, China, to provide references for clinical practice. MATERIAL AND METHODS We collected 274 maxillary posterior teeth in Guizhou Province, China. The root canal curvature was observed by X-ray film measurement. Two hundred teeth were selected to make transparent tooth models, and root canal configuration was recorded according to Vertucci classification criteria. The position of the MB2 root canal orifice and the mesiobuccal root canal configuration were observed b...
Source: Medical Science Monitor - January 15, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Limb-Salvage Outcomes of Arterial Repair Beyond Time Limit at Different Lower-Extremity Injury Sites.
CONCLUSIONS Although limited recanalization of blood vessels may lead to limb complications or amputations over time, the high success rate of limb salvage still merits the surgeon's best efforts. PMID: 33431786 [PubMed - in process] (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 13, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Lumbar Sympathetic Nerve Modulation Using Absolute Ethanol for the Treatment of Primary Lower-Extremity Hyperhidrosis: A Dose-Effect Pilot Study.
Authors: Liu M, Ni H, Tao J, Xie K Abstract BACKGROUND Primary lower-extremity hyperhidrosis (PLEH) can be treated by CT-guided lumbar sympathetic nerve modulation using absolute ethanol. However, doses of ethanol that are too high can cause nerve injury, and doses that are too low have suboptimal results. The present study aimed to investigate the dose-effect relationship of CT-guided lumbar sympathetic nerve modulation with absolute ethanol for PLEH. MATERIAL AND METHODS The study was conducted at the First Affiliated Hospital of Jiaxing University between 07/2014 and 02/2017. Twenty participants were enrolled in...
Source: Medical Science Monitor - January 13, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Personality Traits, Stress, and Emotional Intelligence Associated with Central Serous Chorioretinopathy.
CONCLUSIONS A higher level of perceived stress is the most important psychological risk factor for CSCR. According to our results, a low level of emotional intelligence may be an additional factor that contributes to the occurrence of CSCR. PMID: 33423036 [PubMed - in process] (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 12, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Magnetic Resonance Imaging has Better Accuracy in Detecting New-Onset Rib Fractures as Compared to Computed Tomography.
CONCLUSIONS MRI is highly sensitive for new-onset rib fractures, especially type I, so it is a preferred method for patients with mild chest trauma. PMID: 33424019 [PubMed - in process] (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 12, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Lightwand-Guided Insertion of Flexible Reinforced Laryngeal Mask Airway: Comparison with Standard Digital Manipulation Insertion.
CONCLUSIONS Lightwand-guided f-LMA insertion showed a better fiberoptic laryngeal view than standard digital manipulation, but no improvement in the ventilatory state was observed due to position. Therefore, lightwand-guided insertion could facilitate correct placement of the f-LMA, but it has limited clinical usefulness. PMID: 33428608 [PubMed - as supplied by publisher] (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 12, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Plasma Heat Shock Protein 90 Alpha: A Valuable Predictor of Early Chemotherapy Effectiveness in Advanced Non-Small-Cell Lung Cancer.
This study aimed to investigate the association of HSP90a with chemotherapy in advanced NSCLC. MATERIAL AND METHODS We retrospectively evaluated data from patients admitted to the Department of Respiratory Medicine, Shaoxing People's Hospital, from September 2016 to September 2018 with stage IIIB or IV NSCLC and administered 4 cycles of third-generation platinum-based combination chemotherapy (2 drugs simultaneously). Based on the RECIST1.1 criteria, complete remission (CR), partial response (PR), and stable disease (SD) in 60 cases were determined before and after chemotherapy. Before chemotherapy and after 1, 2, and 4 cy...
Source: Medical Science Monitor - January 11, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Therapeutic Effect of an Anti-Human Programmed Death-Ligand 1 (PD-L1) Nanobody on Polymicrobial Sepsis in Humanized Mice.
CONCLUSIONS KN035, an anti-PD-L1 antibody, can improve the rate of survival in CLP mice and alleviate sepsis-induced apoptosis in the spleen. PMID: 33421049 [PubMed - as supplied by publisher] (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 11, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Comparison of CellSearch and Circulating Tumor Cells (CTC)-Biopsy Systems in Detecting Peripheral Blood Circulating Tumor Cells in Patients with Gastric Cancer.
CONCLUSIONS The CTC-Biopsy system was superior to the CellSearch system for detecting CTCs in GC patients. CTM were detected with the CTC-Biopsy system but not with the CellSearch system. CTCs detected with the CellSearch system correlated with various clinicopathological factors and long-term survival outcomes. PMID: 33408319 [PubMed - in process] (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 9, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Efficacy of 5-Aminolevulinic Acid (ALA)-Photodynamic Therapy (PDT) in Refractory Vulvar Lichen Sclerosus: Preliminary Results.
The objective parameters, female sexual function index (FSFI) and quality of life (QoL) scores, were used before and after treatment to evaluate the clinical curative effect. RESULTS All patients completed 3 treatment cycles of ALA-PDT and follow-up visits. The clinical symptoms of pruritus completely disappeared in 27 cases, and itching improved from severe to mild in 3 cases. The pathological changes of all patients were objectively improved. FSFI score decreased significantly after treatment (P
Source: Medical Science Monitor - January 9, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Respiratory Variations in Peak Peripheral Artery Velocities and Waveforms for Rapid Assessment of Fluid Responsiveness in Traumatic Shock Patients.
This study aimed to assess the correlation between the variability of the end-inspiratory and end-expiratory blood flow waveform and fluid responsiveness (FR) in traumatic shock patients who underwent mechanical ventilation by evaluating peripheral arterial blood flow parameters. MATERIAL AND METHODS A cohort of 60 patients with traumatic shock requiring mechanical ventilation-controlled breathing received ultrasound examinations to assess the velocity of carotid artery (CA), femoral artery (FA) and brachial artery (BA). A rehydration test was performed in which of 250 mL of 0.9% saline was administered within 30 min betwe...
Source: Medical Science Monitor - January 9, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Trends in Workplace Violence Involving Health Care Professionals in China from 2000 to 2020: A Review.
We describe China's past and current clinical practices and health care policies, and we discuss the challenges faced by medical professionals who are victims of hospital-based violence from the perspectives of patients, physicians, hospital leaders, and the government. We conclude by making recommendations for preventing violence in hospital settings. It is urgent for the public to understand that the occupational safety of health care workers must be protected, and treatment should be provided to patients in a harmonious and safe environment. This review aims to describe the trends in workplace violence involving health ...
Source: Medical Science Monitor - January 9, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Secondary Effects of the Rupture and Reconstruction of the Interosseous Talocalcaneal Ligament on the Peritalar Joints.
CONCLUSIONS An ITCL resection can lead to the progressive degeneration of the talonavicular and posterior subtalar joints, while an ITCL reconstruction can be beneficial in restoring the stability of these joints, preventing or postponing their degeneration, and protecting the articular cartilages. PMID: 33402662 [PubMed - in process] (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 8, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Sinomenine Improves Embryo Survival by Regulating Th1/Th2 Balance in a Mouse Model of Recurrent Spontaneous Abortion.
CONCLUSIONS SIN treatment demonstrates a therapeutic effect on spontaneous abortion in RSA mice, possibly through regulating the balance of Th1/Th2 in maternal circulation and decidual tissues. PMID: 33390585 [PubMed - in process] (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 6, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Effect of Parecoxib Sodium on Myocardial Ischemia-Reperfusion Injury Rats.
Authors: Wu F, Wang W, Duan Y, Guo J, Li G, Ma T Abstract BACKGROUND We aimed to explore the effect of parecoxib sodium on myocardial ischemia-reperfusion (I/R) injury rats and its mechanism. MATERIAL AND METHODS The coronary artery of Sprague-Dawley rats was occluded for 6 h of myocardial ischemia, followed by reperfusion for 30 min (I/R group). Before ischemia, parecoxib sodium (10 mg/kg) was intraperitoneally injected twice a day for 3 consecutive days, followed by reperfusion for 6 h (I/R+Pare group). The cardiac function and changes in the infarction area were evaluated via echocardiography in each group. The ...
Source: Medical Science Monitor - January 6, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Utility of Magnetic Resonance Imaging in Diagnosis of Prenatal Non-Visualization of the Fetal Gallbladder: A Case-Series Study.
CONCLUSIONS MRI contributes to identifying PNVGB detected or suspected by ultrasonography. PMID: 33397840 [PubMed - in process] (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 6, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Co-Infection with Common Respiratory Pathogens and SARS-CoV-2 in Patients with COVID-19 Pneumonia and Laboratory Biochemistry Findings: A Retrospective Cross-Sectional Study of 78 Patients from a Single Center in China.
CONCLUSIONS The findings showed that Mycoplasma pneumonia and respiratory syncytial virus were the most common co-infections in patients with COVID-19 pneumonia. Increased levels of PCT in patients with COVID-19 pneumonia were associated with co-infection. PMID: 33388738 [PubMed - in process] (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 5, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Influenza-Associated Encephalopathy and Acute Necrotizing Encephalopathy in Children: A Retrospective Single-Center Study.
Authors: Song Y, Li S, Xiao W, Shen J, Ma W, Wang Q, Yang H, Liu G, Hong Y, Li P, Yang S Abstract BACKGROUND Although influenza primarily affects the respiratory system, it can cause severe neurological complications, especially in younger children, but knowledge about the early indicators of acute necrotizing encephalopathy (ANE) is limited. The main purpose of this article is to summarize the clinical characteristics, diagnosis, and treatment of neurological complications of influenza in children, and to identify factors associated with ANE. MATERIAL AND METHODS This was a retrospective study of children with con...
Source: Medical Science Monitor - January 5, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Regulatory Effect of PD1/PD-Ligand 1 (PD-L1) on Treg Cells in Patients with Idiopathic Pulmonary Fibrosis.
CONCLUSIONS This work identified the molecular mechanism of PD-1 in patients with IPF. It may provide a new perspective on the therapeutic effect of PD-1. PMID: 33386384 [PubMed - as supplied by publisher] (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 3, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Association Between Thyroid Function and Body Composition in Type 2 Diabetes Mellitus (T2DM) Patients: Does Sex Have a Role?
CONCLUSIONS Thyroid function can affect body composition in euthyroid T2DM patients. Thyroid function is more likely to affect the fat and muscle distribution of males than females. PMID: 33387440 [PubMed - as supplied by publisher] (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 3, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Characterization of the Relationship Between the Expression of Aspartate β-Hydroxylase and the Pathological Characteristics of Breast Cancer.
CONCLUSIONS ASPH may be involved in the development of BC and may have utility as a prognostic biomarker in BC. The coexpression of ASPH-associated genes may also be beneficial in improving BC prognosis. PMID: 33380715 [PubMed - in process] (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 2, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Piperine Inhibits Cell Proliferation and Induces Apoptosis of Human Gastric Cancer Cells by Downregulating Phosphatidylinositol 3-Kinase (PI3K)/Akt Pathway.
CONCLUSIONS Our findings suggest that piperine inhibits proliferation and induces apoptosis of human gastric cancer cells through inhibition of the PI3K/Akt signaling pathway. PMID: 33382670 [PubMed - in process] (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 2, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Comparison of Oncoplastic Breast-Conserving Therapy and Standard Breast-Conserving Therapy in Early-Stage Breast Cancer Patients.
CONCLUSIONS OBCT had better cosmetic effects, fewer complications, and no adverse effects on metastasis and recurrence. PMID: 33384404 [PubMed - in process] (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 2, 2021 Category: Research Tags: Med Sci Monit Source Type: research

A Novel Instant 3-Dimensional Printing System for Postoperative Fracture Patients: A Comparative Cohort Study.
Authors: Chen L, Xiong Y, Mi B, Yan C, Xie X, He Z, Zhou W, Liu G Abstract BACKGROUND Traditional plaster (TP) is a widely used auxiliary fixation (AF) approach for postoperative fracture patients. However, patient discomfort and inconvenience to clinicians has limited its application. We introduce a novel instant 3-dimensional printing appliance system (3D-AS) to address such issues. MATERIAL AND METHODS Twenty-seven postoperative fracture patients were divided randomly between a TP group and a 3D-AS group, and analyzed retrospectively. Radiographic images during follow-up were evaluated for fracture healing and f...
Source: Medical Science Monitor - January 2, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Hypertension Among Hemorrhagic Stroke Patients in Northeast China: A Population-Based Study 2017-2019.
CONCLUSIONS The high prevalence of uncontrolled hypertension and high rates of blood pressure at stages 2 and 3 in patients with prior hemorrhagic stroke indicated a considerable stroke burden in northeast China. Therefore, effective and long-time management of hypertension in stroke survivors should be a priority. PMID: 33376232 [PubMed - in process] (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 1, 2021 Category: Research Tags: Med Sci Monit Source Type: research