Impact of Arterial Hypertension on the Eye: A Review of the Pathogenesis, Diagnostic Methods, and Treatment of Hypertensive Retinopathy
Med Sci Monit. 2022 Jan 20;28:e935135. doi: 10.12659/MSM.935135.ABSTRACTThe number of patients with arterial hypertension is continually increasing. Hypertension can cause organ complications, called hypertension-mediated organ damage (HMOD). One example is hypertensive retinopathy, in which high blood pressure (BP) damages both the retinal microcirculation and the retinal nerve fiber layer (RNFL). This can result in progressive and painless vision deterioration in some groups of patients. Unlike anywhere else in the human body, the microvasculature of the retina can be observed in vivo, and the progression of changes can ...
Source: Medical Science Monitor - January 20, 2022 Category: Research Authors: Jacek Dziedziak Anna Zaleska- Żmijewska Jacek Pawe ł Szaflik Agnieszka Cudnoch-J ędrzejewska Source Type: research

Role of NLRP3 Inflammasome in Myocardial Ischemia-Reperfusion Injury and Ventricular Remodeling
Med Sci Monit. 2022 Jan 19;28:e934255. doi: 10.12659/MSM.934255.ABSTRACTReperfusion therapy is the optimal therapy for acute myocardial infarction (AMI), but acute inflammatory injury and chronic heart failure (HF) after myocardial ischemia and reperfusion (MI/R) remain the leading cause of death after AMI. Pyroptosis, a newly discovered form of cell death, has been proven to play a significant role in the acute reperfusion process and the subsequent chronic process of ventricular remodeling. Current research shows that multiple stimuli activate the pyroptotic signaling pathway and contribute to cell death and nonbacterial...
Source: Medical Science Monitor - January 19, 2022 Category: Research Authors: Shichun Shen Zhen Wang Haozhong Sun Likun Ma Source Type: research

Use of a Brain Navigator to Identify the Precentral Knob of the Precentral Gyrus in Normal Subjects
CONCLUSIONS [color=black]This study showed that the anatomical location of the precentral knob in normal subjects could be identified using a brain navigator and this method may be used clinically for patients requiring neuromodulation.[/color].PMID:35039469 | DOI:10.12659/MSM.935181 (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 18, 2022 Category: Research Authors: Sung Ho Jang Han Do Lee Eun Bi Choi Source Type: research

Retracted: The Nephroprotective Effect of TNF Receptor-Associated Factor 6 (TRAF6) Blockade on LPS-Induced Acute Renal Injury Through the Inhibition if Inflammation and Oxidative Stress
Med Sci Monit. 2022 Jan 18;28:e936124. doi: 10.12659/MSM.936124.ABSTRACTThis publication has been retracted by the Editor due to the identification of non-original figure images and manuscript content that raise concerns regarding the credibility and originality of the study and the manuscript. Reference: Xuemei Chen, Yiqing Zhao, Jiajun Xu, Jiachun Bao, Junyao Zhao, Jingfeng Chen, Guowei Chen, Jibo Han. The Nephroprotective Effect of TNF Receptor-Associated Factor 6 (TRAF6) Blockade on LPS-Induced Acute Renal Injury Through the Inhibition if Inflammation and Oxidative Stress. Med Sci Monit, 2020; 26: e919698. DOI: 10.1265...
Source: Medical Science Monitor - January 18, 2022 Category: Research Authors: Xuemei Chen Yiqing Zhao Jiajun Xu Jiachun Bao Junyao Zhao Jingfeng Chen Guowei Chen Jibo Han Source Type: research

Epidemiology of Birth Defects in Eastern China and the Associated Risk Factors
CONCLUSIONS Different risks factors can influence BD development and potentially help to predict specific BD types, such as demographic features and harmful exposure in early pregnancy.PMID:35034947 | DOI:10.12659/MSM.933782 (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 17, 2022 Category: Research Authors: Qiao-Qiao Wang Cha-Ying He Jin Mei Yi-Lin Xu Source Type: research

Junctional Adhesion Molecule-Like Protein (JAML) Is Correlated with Prognosis and Immune Infiltrates in Lung Adenocarcinoma
This study aimed to evaluate the role of JAML in the prognosis and immune infiltrates of lung adenocarcinoma (LUAD). MATERIAL AND METHODS JAML expressions in LUAD tissues and normal tissues were compared using The Cancer Genome Atlas (TCGA) database and datasets from the Gene Expression Omnibus (GEO) database. The influence of JAML expression on prognosis was analyzed by Kaplan-Meier curve and Cox regression model. Interactive and functional analyses of JAML were performed by LinkedOmics and GeneMANIA databases. TIMER2.0, TISIDB, and GEPIA2 databases were used to investigate the correlation between JAML expression and immu...
Source: Medical Science Monitor - January 16, 2022 Category: Research Authors: Likui Fang Wenfeng Yu Guocan Yu Fangming Zhong Bo Ye Source Type: research

Prediction of Patient Survival with Psoas Muscle Density Following Transjugular Intrahepatic Portosystemic Shunts: A Retrospective Cohort Study
CONCLUSIONS PMD has appreciable clinical value for predicting the mortality of patients with TIPS implantation. In addition, PMD is superior to established scoring systems for identifying high-risk patients with a poor prognosis.PMID:35031594 | DOI:10.12659/MSM.934057 (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 15, 2022 Category: Research Authors: Biyu Zhang Weimin Cai Feng Gao Xinran Lin Ting Qian Kaier Gu Bingxin Song Tanzhou Chen Source Type: research

H2A Histone Family Member Z (H2AFZ) Serves as a Prognostic Biomarker in Lung Adenocarcinoma: Bioinformatic Analysis and Experimental Validation
CONCLUSIONS H2AFZ was upregulated in LUAD and related to poor prognosis of LUAD patients; thus, it could be an underlying prognostic biomarker correlated with immune infiltration in LUAD.PMID:35027526 | DOI:10.12659/MSM.933447 (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 14, 2022 Category: Research Authors: Zongkuo Li Menglong Hu Jinhuan Qiu Junkai Feng Ruizhen Zhang Huifang Wu Guiming Hu Jingli Ren Source Type: research

Comprehensive Analysis of Tripterine Anti-Ovarian Cancer Effects Using Weighted Gene Co-Expression Network Analysis and Molecular Docking
CONCLUSIONS Tripterine may be involved in megakaryocyte development and platelet production through potential genes ARHGAP11A, MUC1, HBB, RUNX1T1, and FUT8 and may have an anti-ovarian cancer effect in immune factors signaling, transporting and exchanging oxygen pathways, and autophagy pathways, through these 5 key genes.PMID:35022380 | DOI:10.12659/MSM.932139 (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 13, 2022 Category: Research Authors: Xi Long Leping Liu Qinyu Zhao Xinyi Xu Pingan Liu Guoming Zhang Jie Lin Source Type: research

Retrospective Study of Surgical Outcomes in 60 Patients with Crohn Disease from a Single Center in Poland
CONCLUSIONS Although the analysis did not reveal any risk factors for perioperative complications, perianal manifestations, penetrating disease type, ileal/ileocecal involvement, and smoking may be associated with risk of earlier surgery or multiple surgeries.PMID:35017460 | DOI:10.12659/MSM.934463 (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 12, 2022 Category: Research Authors: Karolina Majewska Cezary Rusinowski Beata Jab łońska Dariusz Go łka S ławomir Mrowiec Source Type: research

Association Between Hyperhomocysteinemia Combined with Metabolic Syndrome and Higher Prevalence of Stroke in Chinese Adults Who Have Elevated Blood Pressure
Med Sci Monit. 2022 Jan 11;28:e934100. doi: 10.12659/MSM.934100.ABSTRACTBACKGROUND Hyperhomocysteinemia (HHcy) and metabolic syndrome (MS) are established cardiovascular risk factors of stroke and are frequently associated with hypertension. However, studies on the association between HHcy combined with MS and stroke risk in hypertensive patients were absent. MATERIAL AND METHODS In 14 059 selected participants with elevated blood pressure, we assessed the prevalence of the MS and stroke. We defined HHcy as plasma total homocysteine>15 μmol/L. MS was defined according to the Chinese Diabetes Society (CDS) criterion. ...
Source: Medical Science Monitor - January 11, 2022 Category: Research Authors: Feng Hu Shichao Yu Juan Li Wei Zhou Tao Wang Xiao Huang Huihui Bao Xiaoshu Cheng Source Type: research

Expression of Long Non-Coding RNA (lncRNA) SNHG5 in Patients with Refractory Diabetic Macular Edema and Its Regulatory Mechanism
CONCLUSIONS SNHG5 correlates with the development of DME and is a potential target for therapy.PMID:35001073 | DOI:10.12659/MSM.932996 (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 10, 2022 Category: Research Authors: Junwen He Zhang Rui Jing Gao Yanhong Chen Yanzi Li Tao Xu Shan Wang Source Type: research

Effect of Combined Thoracic Paravertebral Block and General Anesthesia vs General Anesthesia Alone on Postoperative Stress and Pain in Patients Undergoing Laparoscopic Radical Nephrectomy
Med Sci Monit. 2022 Jan 9;28:e933623. doi: 10.12659/MSM.933623.ABSTRACTBACKGROUND This single-center study compared the effect of combined thoracic paravertebral block (TPVB) and general anesthesia vs general anesthesia alone on postoperative stress and pain in patients undergoing laparoscopic radical nephrectomy. MATERIAL AND METHODS Patients undergoing laparoscopic radical nephrectomy were selected and randomized into a study group given TPVB combined with general anesthesia (n=43) and a reference group (n=43) given general anesthesia. The perioperative clinical indicators, blood pressure, pulse rate, visual analog scale...
Source: Medical Science Monitor - January 9, 2022 Category: Research Authors: Tao Tang Fengjiao Lang Shoulin Gao Li Chen Source Type: research

Oblique Lateral Interbody Fusion with Anterolateral Screw Fixation Is as Effective as with Posterior Percutaneous Pedicle Screw Fixation in Treating Single-Segment Mild Degenerative Lumbar Diseases
This study aimed to compare the clinical efficacy and safety of oblique lateral interbody fusion with anterolateral screw fixation and with posterior percutaneous screw fixation in treating single-segment mild degenerative lumbar diseases. MATERIAL AND METHODS A retrospective analysis was performed on 51 patients with single-segment mild degenerative lumbar diseases who received OLIF from April 2017 to January 2020 in Hong Hui Hospital, Xi'an Jiao Tong University; 24 and 27 patients received OLIF with anterolateral screw fixation (OLIF+AF) and OLIF with posterior percutaneous screw fixation (OLIF+PF), respectively. Anesthe...
Source: Medical Science Monitor - January 8, 2022 Category: Research Authors: Yunshan Guo Xiaodong Wang Yibing Li Kuo Jiang Bo Chen Jing An Dingjun Hao Huimin Hu Source Type: research

Efficacy and Safety of Light Therapy as a Home Treatment for Motor and Non-Motor Symptoms of Parkinson Disease: A Meta-Analysis
CONCLUSIONS The results of this meta-analysis show strong evidence that LT has significant efficacy on motor and non-motor function in PD patients.PMID:34992207 | DOI:10.12659/MSM.935074 (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 7, 2022 Category: Research Authors: Wenjie Sun Junqiang Yan Jiannan Wu Hongxia Ma Source Type: research

Effect of Antibiotic Exposure on Upper Respiratory Tract Bacterial Flora
CONCLUSIONS Antibiotic exposure did not lead to perturbations in general composition of upper airway flora within 6 months, although the incidence of methicillin resistance in coagulase-positive and -negative Staphylococci demonstrated significant increases when patients received antibiotic during the last month. This should be considered in case of broad-spectrum antibiotic administration, since methicillin resistance increases the morbidity and mortality of nosocomial Staphylococcus infections.PMID:34987147 | DOI:10.12659/MSM.934931 (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 6, 2022 Category: Research Authors: Hakan Korkmaz Yeliz Çetinkol Mukadder Korkmaz Mustafa Kerem Çalgın Yeliz Ka şko Arıcı Source Type: research

Effect of Twinlight Laser on the Attachment of Human Gingival Fibroblasts to the Root Surface In Vitro
This study aimed to compare the effectiveness of subgingival scaling and root planing with the Twinlight laser, Er: YAG laser, and hand instrumentation on the removal of endotoxin and attachment of human gingival fibroblasts (HGFs) to cementum surfaces in vitro. MATERIAL AND METHODS Single-rooted teeth extracted for periodontal disease were collected and divided into 3 groups: group A, root planing with Gracey curet no. 5/6; group B, irradiation with Er: YAG laser; group C, irradiation with Er: YAG laser and Nd: YAG laser. Endotoxins were determined by the limulus amebocyte lysate test. Cell attachment and proliferation of...
Source: Medical Science Monitor - January 5, 2022 Category: Research Authors: Jianing Song Han Zheng Mingxuan Wu Xiaoman Guo Taohong Liu Source Type: research

Activation of α7 Nicotinic Acetylcholine Receptor by its Selective Agonist Improved Learning and Memory of Amyloid Precursor Protein/Presenilin 1 (APP/PS1) Mice via the Nrf2/HO-1 Pathway
CONCLUSIONS The results indicated that the activation of alpha7 nAChR by PNU improved the learning and memory of mice carrying the APP/PS1 mutation, regulated the levels of enzymes that mediate APP metabolization to reduce ß-amyloid peptide damage, and decreased the level of oxidative stress and maintained synaptic plasticity, in which the mechanism might be enhancement of the Nrf2/HO-1 pathway.PMID:34980874 | DOI:10.12659/MSM.933978 (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 4, 2022 Category: Research Authors: Kun Cao Jie Xiang Yang-Ting Dong Yi Xu Zhi-Zhong Guan Source Type: research

Relationships Between Obstructive Sleep Apnea and Cardiovascular Disease: A Bibliometric Analysis (2010-2021)
CONCLUSIONS This study provides insight and valuable information for researchers and helps to identify new perspectives concerning potential collaborators and cooperative institutions, hot topics, and research frontiers in this field.PMID:34975145 | DOI:10.12659/MSM.933448 (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 3, 2022 Category: Research Authors: Yumeng Wang Xintian Shou Yang Wu Zongjing Fan Jie Cui Rui Zhuang Ruixiang Luo Source Type: research

Retrospective Study of 573 Patients with Heart Failure Evaluated for Coronary Artery Disease at Toulouse University Center, France
CONCLUSIONS At our center, CAD was diagnosed in more than half of patients who presented with heart failure with preserved or reduced EF. Older age and male sex were the common risk factors in patients with HFpEF and HFrEF.PMID:34974513 | DOI:10.12659/MSM.934804 (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 2, 2022 Category: Research Authors: Antoine Deney Vanessa Nader Anthony Matta Romain Itier Pauline Fournier Olivier Lairez Nathalie Pizzinat Didier Carri é Fr édéric Boal Michel Galinier Oksana Kunduzova Rania Azar Jerome Roncalli Source Type: research

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Patients
Med Sci Monit. 2022 Jan 1;28:e935952. doi: 10.12659/MSM.935952.ABSTRACTOn 4th November 2021, the first oral antiviral drug for COVID-19, molnupiravir (Lagevrio®), received full regulatory approval from the Medicines and Healthcare Products Regulatory Agency (MHRA) in the UK. Molnupiravir is an orally bioavailable antiviral drug for use at home when a SARS-CoV-2 test is positive. On 22nd December 2022, the FDA granted emergency use authorization (EUA) for the oral antiviral drug, nirmatrelvir/ritonavir (Paxlovid®) for adults and children with mild and moderate COVID-19 at increased risk of progression to severe COVI...
Source: Medical Science Monitor - January 1, 2022 Category: Research Authors: Dinah V Parums Source Type: research

A Statistical Prediction Model for Survival After Kidney Transplantation from Deceased Donors
CONCLUSIONS Our results suggest that the proposed model can predict the mortality risk for patients after kidney transplants and could help kidney specialists choose kidney recipients with better prognosis.PMID:34972813 | DOI:10.12659/MSM.933559 (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 1, 2022 Category: Research Authors: Jia-Shan Pan Yi-Ding Chen Han-Dong Ding Tian-Chi Lan Fei Zhang Jin-Biao Zhong Gui-Yi Liao Source Type: research

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Patients
Med Sci Monit. 2022 Jan 1;28:e935952. doi: 10.12659/MSM.935952.ABSTRACTOn 4th November 2021, the first oral antiviral drug for COVID-19, molnupiravir (Lagevrio®), received full regulatory approval from the Medicines and Healthcare Products Regulatory Agency (MHRA) in the UK. Molnupiravir is an orally bioavailable antiviral drug for use at home when a SARS-CoV-2 test is positive. On 22nd December 2022, the FDA granted emergency use authorization (EUA) for the oral antiviral drug, nirmatrelvir/ritonavir (Paxlovid®) for adults and children with mild and moderate COVID-19 at increased risk of progression to severe COVI...
Source: Medical Science Monitor - January 1, 2022 Category: Research Authors: Dinah V Parums Source Type: research

A Statistical Prediction Model for Survival After Kidney Transplantation from Deceased Donors
CONCLUSIONS Our results suggest that the proposed model can predict the mortality risk for patients after kidney transplants and could help kidney specialists choose kidney recipients with better prognosis.PMID:34972813 | DOI:10.12659/MSM.933559 (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 1, 2022 Category: Research Authors: Jia-Shan Pan Yi-Ding Chen Han-Dong Ding Tian-Chi Lan Fei Zhang Jin-Biao Zhong Gui-Yi Liao Source Type: research

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Patients
Med Sci Monit. 2022 Jan 1;28:e935952. doi: 10.12659/MSM.935952.ABSTRACTOn 4th November 2021, the first oral antiviral drug for COVID-19, molnupiravir (Lagevrio®), received full regulatory approval from the Medicines and Healthcare Products Regulatory Agency (MHRA) in the UK. Molnupiravir is an orally bioavailable antiviral drug for use at home when a SARS-CoV-2 test is positive. On 22nd December 2022, the FDA granted emergency use authorization (EUA) for the oral antiviral drug, nirmatrelvir/ritonavir (Paxlovid®) for adults and children with mild and moderate COVID-19 at increased risk of progression to severe COVI...
Source: Medical Science Monitor - January 1, 2022 Category: Research Authors: Dinah V Parums Source Type: research

A Statistical Prediction Model for Survival After Kidney Transplantation from Deceased Donors
CONCLUSIONS Our results suggest that the proposed model can predict the mortality risk for patients after kidney transplants and could help kidney specialists choose kidney recipients with better prognosis.PMID:34972813 | DOI:10.12659/MSM.933559 (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 1, 2022 Category: Research Authors: Jia-Shan Pan Yi-Ding Chen Han-Dong Ding Tian-Chi Lan Fei Zhang Jin-Biao Zhong Gui-Yi Liao Source Type: research

A Prospective Observational Study of 42 Patients with COVID-19 infection and a History of Hepatitis C Virus Infection and Thyroid Disease with Follow-Up Thyroid Function and Autoantibody Testing
CONCLUSIONS This study supports previous reports of an association between SARS-CoV-2 infection and thyroid dysfunction associated with thyroid autoantibodies. Thyroid function tests may be considered as part of the laboratory work-up in patients with COVID-19.PMID:34969944 | DOI:10.12659/MSM.935075 (Source: Medical Science Monitor)
Source: Medical Science Monitor - December 31, 2021 Category: Research Authors: Dumitru Cristinel Badiu Gabriel Cristian Popescu Anca Zgura Adriana Mercan Stanciu Mihai Daniel Dodot Claudia Mehedintu Letitia Toma Simu Razvan Xenia Bacinschi Bogdan Haineala Source Type: research

Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis of Early COVID-19 and Treated at Home Within 3 Days or After 3 Days of Symptom Onset with Prescribed and Non-Prescribed Treatments Between November 2020 and August 2021
Med Sci Monit. 2021 Dec 30;27:e935379. doi: 10.12659/MSM.935379.ABSTRACTBACKGROUND This retrospective study aimed to investigate outcomes and hospitalization rates in patients with a confirmed diagnosis of early COVID-19 treated at home with prescribed and non-prescribed treatments. MATERIAL AND METHODS The medical records of a cohort of 158 Italian patients with early COVID-19 treated at home were analyzed. Treatments consisted of indomethacin, low-dose aspirin, omeprazole, and a flavonoid-based food supplement, plus azithromycin, low-molecular-weight heparin, and betamethasone as needed. The association of treatment time...
Source: Medical Science Monitor - December 30, 2021 Category: Research Authors: Serafino Fazio Paolo Bellavite Elisabetta Zanolin Peter A McCullough Sergio Pandolfi Flora Affuso Source Type: research

A Questionnaire-Based Study to Evaluate Health-Related Behaviors in 602 Women of Reproductive Age in Poland
This study aimed to use a questionnaire to evaluate the health-related behaviors in women of reproductive age in Poland. MATERIAL AND METHODS The studies were conducted among 602 women of reproductive age by diagnostic poll method with the use of questionnaire technique. The applied tool was an original on-line questionnaire. A link to the questionnaire was sent to women aged 18-49 years using the snowball sampling technique and was posted on thematic pro-health website forums. RESULTS The majority of women participating in the study exhibited health behaviors on the average level (65.3%; M=7.6). Pro-health behaviors were ...
Source: Medical Science Monitor - December 30, 2021 Category: Research Authors: Gra żyna Bączek Anna Studnicka Sylwia Rychlewicz Agnieszka Iwan Ewa Rzo ńca Mansur Rahnama Source Type: research

Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis of Early COVID-19 and Treated at Home Within 3 Days or After 3 Days of Symptom Onset with Prescribed and Non-Prescribed Treatments Between November 2020 and August 2021
Med Sci Monit. 2021 Dec 30;27:e935379. doi: 10.12659/MSM.935379.ABSTRACTBACKGROUND This retrospective study aimed to investigate outcomes and hospitalization rates in patients with a confirmed diagnosis of early COVID-19 treated at home with prescribed and non-prescribed treatments. MATERIAL AND METHODS The medical records of a cohort of 158 Italian patients with early COVID-19 treated at home were analyzed. Treatments consisted of indomethacin, low-dose aspirin, omeprazole, and a flavonoid-based food supplement, plus azithromycin, low-molecular-weight heparin, and betamethasone as needed. The association of treatment time...
Source: Medical Science Monitor - December 30, 2021 Category: Research Authors: Serafino Fazio Paolo Bellavite Elisabetta Zanolin Peter A McCullough Sergio Pandolfi Flora Affuso Source Type: research

A Questionnaire-Based Study to Evaluate Health-Related Behaviors in 602 Women of Reproductive Age in Poland
This study aimed to use a questionnaire to evaluate the health-related behaviors in women of reproductive age in Poland. MATERIAL AND METHODS The studies were conducted among 602 women of reproductive age by diagnostic poll method with the use of questionnaire technique. The applied tool was an original on-line questionnaire. A link to the questionnaire was sent to women aged 18-49 years using the snowball sampling technique and was posted on thematic pro-health website forums. RESULTS The majority of women participating in the study exhibited health behaviors on the average level (65.3%; M=7.6). Pro-health behaviors were ...
Source: Medical Science Monitor - December 30, 2021 Category: Research Authors: Gra żyna Bączek Anna Studnicka Sylwia Rychlewicz Agnieszka Iwan Ewa Rzo ńca Mansur Rahnama Source Type: research

Value of Ocular Endoscopy in Extraction of Intraocular Foreign Bodies of Cilia in Patients with Open Ocular Trauma
Med Sci Monit. 2021 Dec 29;27:e932970. doi: 10.12659/MSM.932970.ABSTRACTBACKGROUND The aim of this study was to analyze the value of ocular endoscopy in detecting and extracting intraocular cilia in patients with ocular trauma. MATERIAL AND METHODS We retrospectively analyzed data on identification and extraction of 46 intraocular cilia in 16 eyes with open-globe injury during endoscope-assisted vitrectomy. RESULTS A total of the 16 patients with open-globe injury were operated on from September 2002 to June 2019. The cornea in 14 eyes was cloudy. Two eyes had endophthalmitis and 13 eyes had retinal detachment. A total of ...
Source: Medical Science Monitor - December 29, 2021 Category: Research Authors: Youyou Zha Shu Du Shaoli Wang Hui Ren Jie Yu Xun Yang Source Type: research

A Review of the Impact of Neutrophils and Neutrophil Extracellular Traps (NETs) on the Development of Aortic Aneurysms in Animal and Human Studies
Med Sci Monit. 2021 Dec 28;27:e935134. doi: 10.12659/MSM.935134.ABSTRACTThe pathogenesis of the aortic aneurysm (AA) includes several mechanisms, such as chronic sterile inflammation and homeostasis imbalance, with arteriosclerosis, hemodynamic forces, and genetic factors. In addition to the roles of these processes in the development of AA, neutrophilic activity may play a pivotal role (mostly in inflammation and thrombus formation). Neutrophils, which play a crucial role in innate immunity, can release neutrophil extracellular traps (NETs), one of the mechanisms against fighting pathogens, beside phagocytosis and degranu...
Source: Medical Science Monitor - December 28, 2021 Category: Research Authors: Milena Michalska Tadeusz Grochowiecki Tomasz Jakimowicz S ławomir Nazarewski Source Type: research

A Retrospective Single-Center Study of 23 Patients to Compare Gait Before and After Total Hip Arthroplasty Using the S-ROM Modular Hip System
CONCLUSIONS The findings from this retrospective study showed that ROM and HHS significantly improved following THA with the S-ROM® hip prosthesis, but that gait did not completely return to normal.PMID:34955528 | DOI:10.12659/MSM.934558 (Source: Medical Science Monitor)
Source: Medical Science Monitor - December 27, 2021 Category: Research Authors: Jacqueline Bahr Dietmar Rosental Tim Classen Sonja Krebs Marcus J äger Source Type: research

Retracted: Knockdown of MicroRNA-122 Protects H9c2 Cardiomyocytes from Hypoxia-Induced Apoptosis and Promotes Autophagy
Med Sci Monit. 2021 Dec 13;27:e935767. doi: 10.12659/MSM.935767.ABSTRACTThis publication has been retracted by the Editor due to the identification of non-original figure images and manuscript content that raise concerns regarding the credibility and originality of the study and the manuscript.Reference:Zaiwei Zhang, Hu Li, Shasha Chen, Ying Li, Zhiyuan Cui, Jie Ma. Knockdown of MicroRNA-122 Protects H9c2 Cardiomyocytes from Hypoxia-Induced Apoptosis and Promotes Autophagy. Med Sci Monit, 2017; 23: 4284-4290. DOI: 10.12659/MSM.902936.PMID:34955530 | DOI:10.12659/MSM.935767 (Source: Medical Science Monitor)
Source: Medical Science Monitor - December 27, 2021 Category: Research Authors: Zaiwei Zhang Hu Li Shasha Chen Ying Li Zhiyuan Cui Jie Ma Source Type: research

A Comparative Study of the Clinical Efficacy and Safety of Pneumatic Trabeculoplasty and Selective Laser Trabeculoplasty for Patients with Primary Open-Angle Glaucoma or Ocular Hypertension
CONCLUSIONS Both PNT and SLT can reduce the IOP of patients with POAG and OHT. PNT appears to have better short-term treatment efficiency than SLT.PMID:34958655 | DOI:10.12659/MSM.933454 (Source: Medical Science Monitor)
Source: Medical Science Monitor - December 27, 2021 Category: Research Authors: Yanling Song Qiujie Song Yanhui Qin Jinfeng Xu Ping Chen Hong Li Wenjie Han Source Type: research

A Retrospective Single-Center Study of 23 Patients to Compare Gait Before and After Total Hip Arthroplasty Using the S-ROM Modular Hip System
CONCLUSIONS The findings from this retrospective study showed that ROM and HHS significantly improved following THA with the S-ROM® hip prosthesis, but that gait did not completely return to normal.PMID:34955528 | DOI:10.12659/MSM.934558 (Source: Medical Science Monitor)
Source: Medical Science Monitor - December 27, 2021 Category: Research Authors: Jacqueline Bahr Dietmar Rosental Tim Classen Sonja Krebs Marcus J äger Source Type: research

Retracted: Knockdown of MicroRNA-122 Protects H9c2 Cardiomyocytes from Hypoxia-Induced Apoptosis and Promotes Autophagy
Med Sci Monit. 2021 Dec 13;27:e935767. doi: 10.12659/MSM.935767.ABSTRACTThis publication has been retracted by the Editor due to the identification of non-original figure images and manuscript content that raise concerns regarding the credibility and originality of the study and the manuscript.Reference:Zaiwei Zhang, Hu Li, Shasha Chen, Ying Li, Zhiyuan Cui, Jie Ma. Knockdown of MicroRNA-122 Protects H9c2 Cardiomyocytes from Hypoxia-Induced Apoptosis and Promotes Autophagy. Med Sci Monit, 2017; 23: 4284-4290. DOI: 10.12659/MSM.902936.PMID:34955530 | DOI:10.12659/MSM.935767 (Source: Medical Science Monitor)
Source: Medical Science Monitor - December 27, 2021 Category: Research Authors: Zaiwei Zhang Hu Li Shasha Chen Ying Li Zhiyuan Cui Jie Ma Source Type: research

A Comparative Study of the Clinical Efficacy and Safety of Pneumatic Trabeculoplasty and Selective Laser Trabeculoplasty for Patients with Primary Open-Angle Glaucoma or Ocular Hypertension
CONCLUSIONS Both PNT and SLT can reduce the IOP of patients with POAG and OHT. PNT appears to have better short-term treatment efficiency than SLT.PMID:34958655 | DOI:10.12659/MSM.933454 (Source: Medical Science Monitor)
Source: Medical Science Monitor - December 27, 2021 Category: Research Authors: Yanling Song Qiujie Song Yanhui Qin Jinfeng Xu Ping Chen Hong Li Wenjie Han Source Type: research

A Retrospective Evaluation of Operative and Postoperative Outcomes in Patients with Spinal Metastases from a Single Center to Compare Vertebrectomy with Combined Vertebrectomy and Radiofrequency Ablation
Med Sci Monit. 2021 Dec 26;27:e932995. doi: 10.12659/MSM.932995.ABSTRACTBACKGROUND This retrospective study was conducted at a single center and aimed to evaluate operative and postoperative outcomes in patients with spinal metastases using vertebrectomy and combined vertebrectomy and radiofrequency ablation (RFA). MATERIAL AND METHODS Patients diagnosed with spinal metastases between April 2009 and March 2016 (n=49) included patients who underwent vertebrectomy (n=26) and patients who underwent combined vertebrectomy and RFA (n=23). The characteristics of the 2 groups were similar in primary tumor types, comorbidities, To...
Source: Medical Science Monitor - December 26, 2021 Category: Research Authors: Xiuxin Han Chao Zhang Lili Li Yulin Ma Guowen Wang Source Type: research

Association of Perioperative Myocardial Injury with 30-Day and Long-Term Mortality in Older Adult Patients Undergoing Orthopedic Surgery in China
Med Sci Monit. 2021 Dec 25;27:e932036. doi: 10.12659/MSM.932036.ABSTRACTBACKGROUND Myocardial injury after noncardiac surgery (MINS) is common and associated with postoperative mortality. We assessed MINS occurrence and association with 30-day and long-term mortality in older adult patients undergoing orthopedic surgery in China. MATERIAL AND METHODS This was a retrospective study of consecutive patients who underwent orthopedic surgery between January 1, 2009, and December 31, 2017, at Beijing Jishuitan Hospital. MINS was defined as postoperative troponin I peak elevation above the 99th percentile upper reference limit (&...
Source: Medical Science Monitor - December 25, 2021 Category: Research Authors: Wenlan Hu Youzhou Chen Kaiping Zhao Jihong Wang Mei Zheng Ying Zhao Hao Han Qiong Zhao Xingshan Zhao Source Type: research