Sensing Glucose in the Central Melanocortin Circuits of Rainbow Trout: A Morphological Study

This study was supported by research grants from Spanish Agencia Estatal de Investigación (AEI) and European Fund of Regional Development (FEDER) to JC-R (AGL2016-74857-C3-3-R) and JS (AGL2016-74857-C3-1-R). CO-R has a predoctoral fellowship from AEI (BES-2014-068040). Conflict of Interest Statement The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. References 1. Blouet C, Schwartz GJ. Hypothalamic nutrient sensing in the control of energy homeostasis. Behav Brain Res. (2010) 209:1–12. doi: 10.1016/j.bbr.2009.12.024 PubMed Abstract | CrossRef Full Text | Google Scholar 2. Efeyan A, Comb WC, Sabatini DM. Nutrient sensing mechanisms and pathways. Nature. (2015) 517:302–10. doi: 10.1038/nature14190 PubMed Abstract | CrossRef Full Text | Google Scholar 3. Polakof S, Mommsen TP, Soengas JL. Glucosensing and glucose homeostasis: from fish to mammals. Comp Biochem Physiol B. (2011) 160:123–49. doi: 10.1016/j.cbpb.2011.07.006 PubMed Abstract | CrossRef Full Text | Google Scholar 4. Kurita H, Xu KY, Maejima Y, Nakata M, Dezaki K, Santoso P, et al. Arcuate Na+,K+-ATPase senses systemic energy states and regulates feeding behavior through glucose-inhibited neurons. Am J Physiol Endocrinol Metab. (2015) 309:E320–33. doi: 10.1152/ajpendo.00446.2014 PubMed Abstract | CrossRef Full Text | Goog...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research