'Little brain' or cerebellum not so little after all
(San Diego State University) When we say someone has a quick mind, it may be in part thanks to our expanded cerebellum that distinguishes human brains from those of macaque monkeys, for example.High-res imaging shows the cerebellum is 80% of the area of the cortex, indicating it has grown as human behavior and cognition evolved. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 31, 2020 Category: International Medicine & Public Health Source Type: news

Cerebellar Purkinje cell activity modulates aggressive behavior - Jackman SL, Chen CH, Offermann HL, Drew IR, Harrison BM, Bowman AM, Flick KM, Flaquer I, Regehr WG.
Although the cerebellum is traditionally associated with balance and motor function, it also plays wider roles in affective and cognitive behaviors. Evidence suggests that the cerebellar vermis may regulate aggressive behavior, though the cerebellar circui... (Source: SafetyLit)
Source: SafetyLit - May 2, 2020 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Don ’t Feel Bad if Your Kids Are Gaming More Than Ever. In Fact, Why Not Join Them?
I’ve been thinking an awful lot about the 1989 Detroit Pistons over the past few days. Rick Mahorn, the starting power forward, can’t make a goddamn layup. Neither can Dennis Rodman. Isaiah Thomas is missing too many shots. Do I have anyone on my team who can stop Michael Jordan, who over the past four games is averaging 83.5 points per game against a squad once known as “The Bad Boys” because of its nasty defensive disposition? I’m not seeing much Bad in these Boys. Yeah, it would probably be sorry enough if I was consumed by the actual Detroit team that last played an actual NBA game at the...
Source: TIME: Health - April 22, 2020 Category: Consumer Health News Authors: Sean Gregory Tags: Uncategorized COVID-19 UnitedWeRise20Disaster Video Games Source Type: news

What Types of Memory Impairments are There in Children?
Discussion Memory is an important part of what distinguishes higher order species from others. Memory also is part of one’s self-identity. Difficulties in short-term memory can make common, everyday tasks difficult for the person experiencing the problem particularly if it recently occurred and the person’s long-term memory is intact. Difficulties with long-term memory can also have problems when language, events or even one’s own identity are affected. For some people the memory loss is temporary but for others, memory impairments are permanent and must be accepted and accommodated as part of the overall...
Source: PediatricEducation.org - March 30, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

AI can help diagnose bipolar disorder on MRI exams
Artificial intelligence (AI)-based analysis of neuroimaging and neurocognitive...Read more on AuntMinnie.comRelated Reading: What issues are hindering AI's utility in radiology? AI in radiology? Patients are cautiously optimistic AI characterizes complex mood disorders from fMRI Can AI predict treatment response in bipolar patients? MRI links bipolar disease to cerebellum changes (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - March 11, 2020 Category: Radiology Source Type: news

Sleep deprivation directly following eyeblink-conditioning impairs memory consolidation - De Zeeuw CI, Canto CB.
The relation between sleep and different forms of memory formation continues to be a relevant topic in our daily life. Sleep has been found to affect cerebellum-dependent procedural memory formation, but it remains to be elucidated to what extent the level... (Source: SafetyLit)
Source: SafetyLit - January 20, 2020 Category: International Medicine & Public Health Tags: Distraction, Fatigue, Chronobiology, Vigilance, Workload Source Type: news

Mitochondria from Different Brain Cells Have Different Proteins
Organelles isolated from two types of neurons and a nonneuronal astrocyte in the mouse cerebellum showed varying levels of proteins, hinting at functional differences. (Source: The Scientist)
Source: The Scientist - December 1, 2019 Category: Science Tags: The Literature Source Type: news

Mice Brains May Be Too Different From Humans ’ To Be Accurate Research Model, Study Says
New research has found key differences between the cerebellum of mice and that of humans. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - October 28, 2019 Category: Pharmaceuticals Authors: Dana Dovey, Contributor Source Type: news

Spatiotemporal expansion of primary progenitor zones in the developing human cerebellum
We present histological and molecular analyses of the developing human cerebellum from 30 days after conception to 9 months after birth. Differences in developmental patterns between humans and mice include spatiotemporal expansion of both ventricular and rhombic lip primary progenitor zones to include subventricular zones containing basal progenitors. The human rhombic lip persists longer through cerebellar development than in the mouse and undergoes morphological changes to form a progenitor pool in the posterior lobule, which is not seen in other organisms, not even in the nonhuman primate the macaque. Disruptions in hu...
Source: ScienceNOW - October 24, 2019 Category: Science Authors: Haldipur, P., Aldinger, K. A., Bernardo, S., Deng, M., Timms, A. E., Overman, L. M., Winter, C., Lisgo, S. N., Razavi, F., Silvestri, E., Manganaro, L., Adle-Biasette, H., Guilmiot, F., Russo, R., Kidron, D., Hof, P. R., Gerrelli, D., Lindsay, S. J., Doby Tags: Medicine, Diseases, Neuroscience r-articles Source Type: news

New Finding Challenges Old Notions About Dyslexia
THURSDAY, Oct. 10, 2019 -- The cerebellum does not affect reading ability in people with dyslexia, according to a new study that challenges a controversial theory. The cerebellum is a brain structure traditionally involved in motor function. Some... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - October 10, 2019 Category: General Medicine Source Type: news

Cerebellar Surprises
Kamran Khodakhah, a researcher at the Albert Einstein College of Medicine, describes the cerebellum's newly described role in addictive and social behaviors. (Source: The Scientist)
Source: The Scientist - October 1, 2019 Category: Science Tags: Videos Source Type: news

The Cerebellum ’s Secrets: A Profile of Kamran Khodakhah
The Albert Einstein College of Medicine neuroscientist has revealed surprising functions of the brain region, such as its role in the brain ’s rewards circuits and in addiction. (Source: The Scientist)
Source: The Scientist - October 1, 2019 Category: Science Tags: Profile Source Type: news

Researchers map the Alzheimer's brain, discover that one area appears to protect itself against decline
(Natural News) The latest protein maps of the brains of patients with Alzheimer’s disease showed that at least one region succeeded in holding off the ravages of the disease. U.K. researchers believed that the cerebellum’s ability to protect itself against Alzheimer’s might be reproducible in other parts of the brain. They examined the brain and other essential organs... (Source: NaturalNews.com)
Source: NaturalNews.com - September 26, 2019 Category: Consumer Health News Source Type: news

Imaging Technique May Help Predict Stroke-Related Dementia
THURSDAY, Sept. 12, 2019 -- Diffusion tensor image segmentation technique (DSEG), which characterizes microstructural damage across the cerebellum, identifies damage in cerebral small vessel disease (SVD) and can predict dementia, according to a... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - September 12, 2019 Category: Pharmaceuticals Source Type: news

The cerebellum is involved in processing of predictions and prediction errors in a fear conditioning paradigm - Ernst TM, Brol AE, Gratz M, Ritter C, Bingel U, Schlamann M, Maderwald S, Quick HH, Merz CJ, Timmann D.
Prediction errors are thought to drive associative fear learning. Surprisingly little is known about the possible contribution of the cerebellum. To address this question, healthy participants underwent a differential fear conditioning paradigm during 7T m... (Source: SafetyLit)
Source: SafetyLit - September 2, 2019 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Scientific Meeting » New Perspectives on Cerebellar Function: Implications for Mental Health
This NIMH-sponsored symposium will bring together experts in basic and translational neuroscience to discuss the state of the field and identify opportunities to advance our understanding of how the cerebellum contributes to cognition, emotion, and social behavior in both healthy and psychiatric populations. (Source: National Institute of Mental Health)
Source: National Institute of Mental Health - August 13, 2019 Category: Psychiatry Authors: National Institute of Mental Health Source Type: news

Slide-seq: A scalable technology for measuring genome-wide expression at high spatial resolution
Spatial positions of cells in tissues strongly influence function, yet a high-throughput, genome-wide readout of gene expression with cellular resolution is lacking. We developed Slide-seq, a method for transferring RNA from tissue sections onto a surface covered in DNA-barcoded beads with known positions, allowing the locations of the RNA to be inferred by sequencing. Using Slide-seq, we localized cell types identified by single-cell RNA sequencing datasets within the cerebellum and hippocampus, characterized spatial gene expression patterns in the Purkinje layer of mouse cerebellum, and defined the temporal evolution of ...
Source: ScienceNOW - March 28, 2019 Category: Science Authors: Rodriques, S. G., Stickels, R. R., Goeva, A., Martin, C. A., Murray, E., Vanderburg, C. R., Welch, J., Chen, L. M., Chen, F., Macosko, E. Z. Tags: Genetics, Molecular Biology reports Source Type: news

Newly discovered role for climbing fibers: Conveying a sensory snapshot to the cerebellum
(Max Planck Florida Institute for Neuroscience) Though there is a wealth knowledge supporting the idea that sensory cues benefit motor learning, the precise brain circuitry and mechanisms tying these two together has been debated in recent years. Shedding new light on this topic, a paper in Neuron from the lab of Dr. Jason Christie at the Max Planck Florida Institute for Neuroscience, has revealed that a special input pathway into the cerebellum seems to hold the key to coding sensory information. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 27, 2019 Category: International Medicine & Public Health Source Type: news

Part of the brain may be 'dementia-proof'
A study by the University of Manchester found people who die from Alzheimer's produce proteins in the brain region known as the cerebellum - but not in five other key areas of the vital organ. (Source: the Mail online | Health)
Source: the Mail online | Health - February 11, 2019 Category: Consumer Health News Source Type: news

Cerebellum connects to brain ’s reward system
A study in mice found that the brain ’s cerebellum—known to play a role in motor coordination—also helps control the brain’s reward circuitry. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - February 5, 2019 Category: Consumer Health News Source Type: news

UCLA-led team uncovers critical new clues about what goes awry in brains of people with autism
This study gives a new critical clue in understanding what has gone awry in the brains of autism patients.”More than 24 million people worldwide are estimated to have autism. In developed countries, about 1.5 percent of children have been diagnosed with autism spectrum disorder as of 2017. The disorder affects communication and behavior, and is marked by problems in social communication and social interaction, and repetitive behaviors.“We need to understand how a panoply of genetic and environmental factors converges to cause autism,” Geschwind said. “RNA editing is an important piece of the autism ...
Source: UCLA Newsroom: Health Sciences - January 30, 2019 Category: Universities & Medical Training Source Type: news

BIDMC researchers ID, treat faulty brain circuitry underlying symptoms of schizophrenia
(Beth Israel Deaconess Medical Center) In a first-of-its-kind study, Beth Israel Deaconess Medical Center researchers determined the underlying anatomical cause of certain symptoms of schizophrenia, then ameliorated them with non-invasive brain stimulation. The scientists reported in the American Journal of Psychiatry that these symptoms arise from a breakdown in a network between the brain's prefrontal cortex and the cerebellum, and that non-invasive brain stimulation restored network function, which in turn improved schizophrenia's most debilitating symptoms. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - January 30, 2019 Category: International Medicine & Public Health Source Type: news

Medical News Today: Key brain area plays a crucial role in addiction
New research finds that the brain's cerebellum is involved in reward processing and social behavior. The findings shed new light on addictive behavior. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 19, 2019 Category: Consumer Health News Tags: Alcohol / Addiction / Illegal Drugs Source Type: news

Science News » New Findings Reveal Surprising Role of the Cerebellum in Reward and Social Behaviors
A new study in rodents has demonstrated, for the first time, that the brain ’ s cerebellum plays a role in controlling reward and social preference behavior — findings that shed light on the brain circuits critical to the affective and social dysfunction seen across multiple psychiatric disorders. (Source: National Institute of Mental Health)
Source: National Institute of Mental Health - January 18, 2019 Category: Psychiatry Authors: Claire Cole Source Type: news

Brain's Cerebellum Found to Influence Addictive and Social Behavior
BRONX, NY—(January 17, 2019)—In a study published online today in the journal Science, researchers atAlbert Einstein College of Medicine, part ofMontefiore, prove for the first time that the brain’s cerebellum—long thought to be mainly involved in coordinating movement—helps control the brain’s reward circuitry. The surprising finding indicates that the cerebellum plays a major role in reward processing and social behaviors and could potentially lead to new strategies for treating addiction. (Source: Einstein News)
Source: Einstein News - January 17, 2019 Category: Universities & Medical Training Source Type: news

New Findings Reveal Surprising Role of the Cerebellum in Reward and Social Behaviors
NIH-funded study sheds new light on brain circuits related to affective and social dysfunction. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - January 17, 2019 Category: American Health Source Type: news

New findings reveal surprising role of the cerebellum in reward and social behaviors
(NIH/National Institute of Mental Health) A study in rodents found that the brain's cerebellum -- known to play a role in motor coordination -- also helps control the brain's reward circuitry. Researchers found a direct neural connection from the cerebellum to the ventral tegmental area (a brain area long known to be involved in reward processing and encoding). The findings shed light on the brain circuits critical to the affective and social dysfunction seen across multiple psychiatric disorders. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 17, 2019 Category: International Medicine & Public Health Source Type: news

The cerebellum gets social
(Source: ScienceNOW)
Source: ScienceNOW - January 17, 2019 Category: Science Authors: D'Angelo, E. Tags: Neuroscience perspective Source Type: news

The cerebellum and reward-driven behavior
(Source: ScienceNOW)
Source: ScienceNOW - January 17, 2019 Category: Science Authors: Stern, P. Tags: Neuroscience twis Source Type: news

Cerebellar modulation of the reward circuitry and social behavior
The cerebellum has been implicated in a number of nonmotor mental disorders such as autism spectrum disorder, schizophrenia, and addiction. However, its contribution to these disorders is not well understood. In mice, we found that the cerebellum sends direct excitatory projections to the ventral tegmental area (VTA), one of the brain regions that processes and encodes reward. Optogenetic activation of the cerebello-VTA projections was rewarding and, in a three-chamber social task, these projections were more active when the animal explored the social chamber. Intriguingly, activity in the cerebello-VTA pathway was require...
Source: ScienceNOW - January 17, 2019 Category: Science Authors: Carta, I., Chen, C. H., Schott, A. L., Dorizan, S., Khodakhah, K. Tags: Neuroscience, Online Only r-articles Source Type: news

Cerebellar Contributions to Major Depression - Depping MS, Schmitgen MM, Kubera KM, Wolf RC.
Extending beyond the motor domain, the cerebellum is involved in various aspects of cognition and affect. Multidisciplinary evidence has demonstrated topographic organization of higher-order cognitive functions within the cerebellum. We here review recent ... (Source: SafetyLit)
Source: SafetyLit - December 19, 2018 Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news

Teenager has a stroke after tearing an artery in his neck on a water slide
The unnamed 16-year-old presented to Rashid Hospital in Dubai after being unable to walk or stand for the past 16 hours. A CT scan revealed he had a stroke in the cerebellum in his brain. (Source: the Mail online | Health)
Source: the Mail online | Health - December 14, 2018 Category: Consumer Health News Source Type: news

Cerebellum Stimulation Improves Gait and Balance After Stroke Cerebellum Stimulation Improves Gait and Balance After Stroke
A new study opens up the cerebellum as a novel brain area of interest in the recovery of stroke patients.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 30, 2018 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

Making moves and memories, are they connected?
(Baylor College of Medicine) Researchers report the first direct evidence that the cerebellum does more than just control muscle activity. It also plays a role in cognitive functions. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 15, 2018 Category: International Medicine & Public Health Source Type: news

Cerebellum Does & ldquo;Quality Control & rdquo; for Our Thoughts: Study
FMRI data uncover wide variation in network organization between individuals in this oft-neglected brain region. (Source: The Scientist)
Source: The Scientist - November 1, 2018 Category: Science Tags: News & Opinion Source Type: news

Cerebellum Does "Quality Control" for Our Thoughts: Study
FMRI data uncover wide variation in network organization between individuals in this oft-neglected brain region. (Source: The Scientist)
Source: The Scientist - November 1, 2018 Category: Science Tags: News & Opinion Source Type: news

Researchers find disrupted functional connectivity in cerebellum of adults with HF-ASD
(Mary Ann Liebert, Inc./Genetic Engineering News) A new study using an unbiased, whole-brain data-driven approach to assess the resting-state functional connectome in young adults with high-functioning autism spectrum disorder (HF-ASD) found two clusters of abnormal connectivity in the cerebellum. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 5, 2018 Category: International Medicine & Public Health Source Type: news

Is there an "antisocial" cerebellum? Evidence from disorders other than autism characterized by abnormal social behaviours - Moreno-Rius J.
The cerebellum is a hindbrain structure which involvement in functions not related to motor control and planning is being increasingly recognized in the last decades. Studies on Autism Spectrum Disorders (ASD) have reported cerebellar involvement on these ... (Source: SafetyLit)
Source: SafetyLit - August 30, 2018 Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news

Cerebellum and cognition in multiple sclerosis: the fall status matters - Schreck LM, Ryan SPP, Monaghan PG.
Kalron et al. report people with Multiple Sclerosis (PwMS) who fall show a decreased cerebellar volume along with decreased overall cognition compared to non-fallers. While this paper focuses on cerebellar and cognitive alterations in PwMS, these findings ... (Source: SafetyLit)
Source: SafetyLit - August 17, 2018 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Mapping of magnetic particles in the human brain
(Ludwig-Maximilians-Universit ä t M ü nchen) LMU researchers have for the first time mapped the distribution of magnetic particles in the human brain. The study reveals that the particles are primarily located in the cerebellum and the brainstem, which are the more ancient parts of the brain. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 31, 2018 Category: International Medicine & Public Health Source Type: news

Researchers Probe Autism's Origins in the Brain
Researchers are looking for clues to autism in the structure of the brain, specifically the cerebellum. (Source: WebMD Health)
Source: WebMD Health - July 12, 2018 Category: Consumer Health News Source Type: news

Autism spectrum disorder linked to shape of brain's cerebellum
(Columbia University Irving Medical Center) Structural differences in the cerebellum may be linked to some aspects of autism spectrum disorder, according to a neuroimaging study from Columbia University Irving Medical Center (CUIMC). (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - July 11, 2018 Category: International Medicine & Public Health Source Type: news

Revealing the mechanism behind animals' sixth sense
(DGIST (Daegu Gyeongbuk Institute of Science and Technology)) A research team in DGIST discovered genes that detect and control movement and identified the motor mechanism of proprioception sense receptors. The finding provides clues to the cause of walking disorders caused by cerebellum damage and degenerative brain diseases. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 10, 2018 Category: Biology Source Type: news

Cannabinoid agonist administration within the cerebellar cortex impairs motor learning - Steinmetz AB, Freeman JH.
Systemic administration of cannabinoid agonists impairs cerebellum- dependent motor learning. The cannabinoid-induced impairment of motor learning has been hypothesized to be due to disruption of Purkinje cell plasticity within the cerebellar cortex. In th... (Source: SafetyLit)
Source: SafetyLit - July 5, 2018 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Complexity of NMDA receptor drug discovery target revealed
(Emory Health Sciences) NMDA receptor assemblies containing the GluN2C subunit are predominant in the cerebellum, and have distinct electrochemical properties, Emory scientists found. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - June 28, 2018 Category: Biology Source Type: news

Conquer Chiari Research Center open house
(University of Akron) Conquer Chiari Research Center (CCRC) will hold an open house on Saturday, July 21, at The University of Akron, Ohio. The CCRC conducts research on Chiari malformation, a congenital neurological condition in which brain tissue extends to the spinal canal, affecting the cerebellum. The open house features research presentations by CCRC faculty and student poster presentations. Dr. Jahangir Maleki, pain neurologist from Cleveland Clinic Foundation, will be keynote. Research will be conducted on site. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 28, 2018 Category: International Medicine & Public Health Source Type: news

New study highlights unique state of 'restful alertness' during Transcendental Meditation
(Maharishi University of Management) A new study using functional magnetic resonance imaging (fMRI) suggests that transcendental meditation is associated with a unique state of 'restful alertness.' The study, which monitored blood flow, found that, compared to eyes-closed rest, during transcendental meditation there was increased activity in the prefrontal cortex, indicating the sort of alertness also seen in other meditations. However, unlike other meditations, there was decreased activity in the cerebellum and pons, indicating deep rest. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 22, 2018 Category: International Medicine & Public Health Source Type: news

In the eye of the medulloblastoma
(CNRS) Can genes normally expressed only in the eye be activated in brain tumors? Such a phenomenon, though surprising, has been observed in certain types of medulloblastoma, pediatric tumors of the cerebellum. Researchers from the CNRS, Institut Curie, Inserm and Universit é Paris-Sud, together with colleagues at St. Jude Children's Research Hospital, have pinpointed the role of these genes in the tumor process, thus offering new therapeutic targets. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - March 12, 2018 Category: Cancer & Oncology Source Type: news

An examination of behavioral and neuronal effects of comorbid traumatic brain injury and alcohol use - Mayer AR, Hanlon FM, Claus ED, Dodd AB, Miller B, Mickey J, Quinn DK, Hagerty SL, Seaman B, Hutchison KE.
BACKGROUND: Chronic alcohol use disorders (AUDs) and traumatic brain injury (TBI) are highly comorbid and share commonly affected neuronal substrates (i.e., prefrontal cortex, limbic system, and cerebellum). However, no studies have examined how combined p... (Source: SafetyLit)
Source: SafetyLit - March 7, 2018 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news