Big contributions of the little brain for precision psychiatry - Anteraper S, Guell X, Whitfield-Gabrieli S.
Our previous work using 3T functional Magnetic Resonance Imaging (fMRI) parcellated the human dentate nuclei (DN), the primary output of the cerebellum, to three distinct functional zones each contributing uniquely to default-mode, salience-motor, and visu... (Source: SafetyLit)
Source: SafetyLit - November 12, 2022 Category: International Medicine & Public Health Tags: Sensing and Response Issues Source Type: news

Infographic: The Cerebellum's Many Roles Beyond Motor Control
Researchers have discovered that the small structure is involved language, emotion, and may other high-order brain processes. (Source: The Scientist)
Source: The Scientist - August 15, 2022 Category: Science Tags: Infographics Magazine Issue Source Type: news

The Cerebellum's Functions in Cognition, Emotion, and More
Once thought of as a mere motor coordination center, the "little brain" is now appreciated as participating in higher neurological processes. (Source: The Scientist)
Source: The Scientist - August 15, 2022 Category: Science Tags: Features Magazine Issue Source Type: news

Cerebellum and emotion in social behavior - Clausi S, Siciliano L, Olivito G, Leggio M.
Accumulating evidence suggests that the cerebellum plays a crucial role not only in the motor and cognitive domains but also in emotions and social behavior. In the present chapter, after a general introduction on the significance of the emotional componen... (Source: SafetyLit)
Source: SafetyLit - August 1, 2022 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Cerebellum anatomy predicts individual risk-taking behavior and risk tolerance - Quan P, He L, Mao T, Fang Z, Deng Y, Pan Y, Zhang X, Zhao K, Lei H, Detre JA, Kable JW, Rao H.
Human risk tolerance is highly idiosyncratic and individuals often show distinctive preferences when faced with similar risky situations. However, the neural underpinnings of individual differences in risk-taking remain unclear. Here we combined structural... (Source: SafetyLit)
Source: SafetyLit - March 31, 2022 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Cerebellar grey matter volumes in reactive aggression and impulsivity in healthy volunteers - Wolfs EML, Klaus J, Schutter DJLG.
Several lines of evidence point towards the involvement of the cerebellum in reactive aggression. In addition to the posterior cerebellar hemisphere, the vermis has been suggested to play a prominent role in impulse regulation. In the present study, we set... (Source: SafetyLit)
Source: SafetyLit - March 7, 2022 Category: International Medicine & Public Health Tags: Violence and Weapons Issues Source Type: news

Senator Ben Ray Luj án undergoes surgery after a stroke
The 49-year-old senator underwent surgery to ease swelling after he was found to have suffered a stroke in his cerebellum that affected his balance. #benrayluján (Source: Reuters: Health)
Source: Reuters: Health - February 2, 2022 Category: Consumer Health News Source Type: news

Democratic Sen. Ben Ray Lujan suffered a stroke, which could complicate Biden's Supreme Court plans
Sen. Ben Ray Lujan, a Democrat, is "expected to make a full recovery" after suffering a stroke in his cerebellum, his chief of staff said in a statement. #chiefofstaff #benraylujan #supremecourt (Source: Reuters: Health)
Source: Reuters: Health - February 1, 2022 Category: Consumer Health News Source Type: news

MOIRA PETTY: Signing up for a drug trial after a stroke really helped me
MOIRA PETTY: My stroke was in the cerebellum, the part of the brain responsible for balance, coordination and posture, as well as helping with eye movement and vision. (Source: the Mail online | Health)
Source: the Mail online | Health - December 21, 2021 Category: Consumer Health News Source Type: news

Prader-Willi Syndrome: New Target for Hunger Suppression? Prader-Willi Syndrome: New Target for Hunger Suppression?
Signaling pathways in the cerebellum, rather than the hypothalamus, could provide a key for developing new therapies for the genetic disorder.Quick Take (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - November 18, 2021 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Largescale brain epigenetics study provides new insights into dementia
(University of Exeter) The team looked in different regions of the brain, which are affected in Alzheimer's disease before looking for common changes across these cortical regions. They identified 220 sites in the genome, including 84 new genes, which showed different levels of DNA methylation in the cortex in individuals with more severe Alzheimer's disease, which weren't seen in the cerebellum. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 10, 2021 Category: International Medicine & Public Health Source Type: news

Cerebellum Plays Crucial Role in Metabolizing Alcohol in Mice
The researchers say these findings challenge dogma in the field, which has given the liver all credit for metabolizing alcohol. (Source: The Scientist)
Source: The Scientist - March 31, 2021 Category: Science Tags: News & Opinion Source Type: news

Binge drinking in adolescence is linked to changes in the cerebellum in young adulthood
(University of Eastern Finland) Binge drinking in adolescence is associated with changes in the volume of the cerebellum in young adulthood, a new study from the University of Eastern Finland and Kuopio University Hospital shows (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 19, 2021 Category: International Medicine & Public Health Source Type: news

Family history of depression is associated with alterations in task-dependent connectivity between the cerebellum and ventromedial prefrontal cortex - Tepfer LJ, Alloy LB, Smith DV.
BACKGROUND: A family history of major depressive disorder (MDD) increases the likelihood of a future depressive episode, which itself poses a significant risk for disruptions in reward processing and social cognition. However, it is unclear whether a famil... (Source: SafetyLit)
Source: SafetyLit - March 11, 2021 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Cerebellar nuclei evolved by repeatedly duplicating a conserved cell-type set
How have complex brains evolved from simple circuits? Here we investigated brain region evolution at cell-type resolution in the cerebellar nuclei, the output structures of the cerebellum. Using single-nucleus RNA sequencing in mice, chickens, and humans, as well as STARmap spatial transcriptomic analysis and whole–central nervous system projection tracing, we identified a conserved cell-type set containing two region-specific excitatory neuron classes and three region-invariant inhibitory neuron classes. This set constitutes an archetypal cerebellar nucleus that was repeatedly duplicated to form new regions. The exc...
Source: ScienceNOW - December 17, 2020 Category: Science Authors: Kebschull, J. M., Richman, E. B., Ringach, N., Friedmann, D., Albarran, E., Kolluru, S. S., Jones, R. C., Allen, W. E., Wang, Y., Cho, S. W., Zhou, H., Ding, J. B., Chang, H. Y., Deisseroth, K., Quake, S. R., Luo, L. Tags: Neuroscience, Online Only r-articles Source Type: news