Is there an "antisocial" cerebellum? Evidence from disorders other than autism characterized by abnormal social behaviours - Moreno-Rius J.
The cerebellum is a hindbrain structure which involvement in functions not related to motor control and planning is being increasingly recognized in the last decades. Studies on Autism Spectrum Disorders (ASD) have reported cerebellar involvement on these ... (Source: SafetyLit)
Source: SafetyLit - August 30, 2018 Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news

Cerebellum and cognition in multiple sclerosis: the fall status matters - Schreck LM, Ryan SPP, Monaghan PG.
Kalron et al. report people with Multiple Sclerosis (PwMS) who fall show a decreased cerebellar volume along with decreased overall cognition compared to non-fallers. While this paper focuses on cerebellar and cognitive alterations in PwMS, these findings ... (Source: SafetyLit)
Source: SafetyLit - August 17, 2018 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Mapping of magnetic particles in the human brain
(Ludwig-Maximilians-Universit ä t M ü nchen) LMU researchers have for the first time mapped the distribution of magnetic particles in the human brain. The study reveals that the particles are primarily located in the cerebellum and the brainstem, which are the more ancient parts of the brain. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 31, 2018 Category: International Medicine & Public Health Source Type: news

Researchers Probe Autism's Origins in the Brain
Researchers are looking for clues to autism in the structure of the brain, specifically the cerebellum. (Source: WebMD Health)
Source: WebMD Health - July 12, 2018 Category: Consumer Health News Source Type: news

Autism spectrum disorder linked to shape of brain's cerebellum
(Columbia University Irving Medical Center) Structural differences in the cerebellum may be linked to some aspects of autism spectrum disorder, according to a neuroimaging study from Columbia University Irving Medical Center (CUIMC). (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - July 11, 2018 Category: International Medicine & Public Health Source Type: news

Revealing the mechanism behind animals' sixth sense
(DGIST (Daegu Gyeongbuk Institute of Science and Technology)) A research team in DGIST discovered genes that detect and control movement and identified the motor mechanism of proprioception sense receptors. The finding provides clues to the cause of walking disorders caused by cerebellum damage and degenerative brain diseases. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 10, 2018 Category: Biology Source Type: news

Cannabinoid agonist administration within the cerebellar cortex impairs motor learning - Steinmetz AB, Freeman JH.
Systemic administration of cannabinoid agonists impairs cerebellum- dependent motor learning. The cannabinoid-induced impairment of motor learning has been hypothesized to be due to disruption of Purkinje cell plasticity within the cerebellar cortex. In th... (Source: SafetyLit)
Source: SafetyLit - July 5, 2018 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Conquer Chiari Research Center open house
(University of Akron) Conquer Chiari Research Center (CCRC) will hold an open house on Saturday, July 21, at The University of Akron, Ohio. The CCRC conducts research on Chiari malformation, a congenital neurological condition in which brain tissue extends to the spinal canal, affecting the cerebellum. The open house features research presentations by CCRC faculty and student poster presentations. Dr. Jahangir Maleki, pain neurologist from Cleveland Clinic Foundation, will be keynote. Research will be conducted on site. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 28, 2018 Category: International Medicine & Public Health Source Type: news

Complexity of NMDA receptor drug discovery target revealed
(Emory Health Sciences) NMDA receptor assemblies containing the GluN2C subunit are predominant in the cerebellum, and have distinct electrochemical properties, Emory scientists found. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - June 28, 2018 Category: Biology Source Type: news

New study highlights unique state of 'restful alertness' during Transcendental Meditation
(Maharishi University of Management) A new study using functional magnetic resonance imaging (fMRI) suggests that transcendental meditation is associated with a unique state of 'restful alertness.' The study, which monitored blood flow, found that, compared to eyes-closed rest, during transcendental meditation there was increased activity in the prefrontal cortex, indicating the sort of alertness also seen in other meditations. However, unlike other meditations, there was decreased activity in the cerebellum and pons, indicating deep rest. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 22, 2018 Category: International Medicine & Public Health Source Type: news

In the eye of the medulloblastoma
(CNRS) Can genes normally expressed only in the eye be activated in brain tumors? Such a phenomenon, though surprising, has been observed in certain types of medulloblastoma, pediatric tumors of the cerebellum. Researchers from the CNRS, Institut Curie, Inserm and Universit é Paris-Sud, together with colleagues at St. Jude Children's Research Hospital, have pinpointed the role of these genes in the tumor process, thus offering new therapeutic targets. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - March 12, 2018 Category: Cancer & Oncology Source Type: news

An examination of behavioral and neuronal effects of comorbid traumatic brain injury and alcohol use - Mayer AR, Hanlon FM, Claus ED, Dodd AB, Miller B, Mickey J, Quinn DK, Hagerty SL, Seaman B, Hutchison KE.
BACKGROUND: Chronic alcohol use disorders (AUDs) and traumatic brain injury (TBI) are highly comorbid and share commonly affected neuronal substrates (i.e., prefrontal cortex, limbic system, and cerebellum). However, no studies have examined how combined p... (Source: SafetyLit)
Source: SafetyLit - March 7, 2018 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Lab-grown human cerebellar cells yield clues to autism
(Boston Children's Hospital) Increasing evidence has linked autism spectrum disorder (ASD) with dysfunction of the brain's cerebellum, but the details have been unclear. In a new study, researchers at Boston Children's Hospital used stem cell technology to create cerebellar cells known as Purkinje cells from patients with tuberous sclerosis complex (TSC), a genetic syndrome that often includes ASD-like features. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 16, 2018 Category: International Medicine & Public Health Source Type: news

A systematic review of the gait characteristics associated with cerebellar ataxia - Buckley E, Mazz à C, McNeill A.
BACKGROUND: Cerebellar Ataxias are a group of gait disorders resulting from dysfunction of the cerebellum, commonly characterised by slowly progressing incoordination that manifests as problems with balance and walking leading to considerable disability. T... (Source: SafetyLit)
Source: SafetyLit - December 11, 2017 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Behavioral therapy increases connectivity in brains of people with OCD
UCLA researchers report that people with obsessive-compulsive disorder, when treated with a special form of talk therapy, demonstrate distinct changes in their brains as well as improvement in their symptoms.In the study, published in  Translational Psychiatry, people with OCD underwent daily cognitive behavioral therapy, or CBT, to learn how to better resist compulsive behaviors and to decrease distress. Within one month, they had developed extensive increases in the strength of the connections between regions of their brains — which may reflect the participants gained new non-compulsive behaviors and thought patterns....
Source: UCLA Newsroom: Health Sciences - September 18, 2017 Category: Universities & Medical Training Source Type: news