Intoxicated aggression: do alcohol and stimulants cause dose-related aggression? A review - Kuypers K, Verkes RJ, Van Den Brink W, van Amsterdam J, Ramaekers JG.
RATIONALE: Violence and drug use are significant public health challenges that are strongly linked. It is known that alcohol plays a major role in the causation of unnatural deaths and that stimulants like cocaine and amphetamine are often implicated in ag... (Source: SafetyLit)
Source: SafetyLit - July 2, 2018 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Medical News Today: What is Evekeo?
Evekeo is an amphetamine-based medication that is used to treat narcolepsy, ADHD, and excess weight. Evekeo is the trade name as there is no generic amphetamine drug. It is a controlled substance, due to the risk of dependence and adverse effects. Find out more about this drug, its uses, and the risks involved. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - June 20, 2018 Category: Consumer Health News Tags: Pharmacy / Pharmacist Source Type: news

Global methamphetamine trends: an evolving problem - Stoneberg DM, Shukla RK, Magness MB.
The methamphetamine (meth) problem is increasing in regions around the world. As the most widely manufactured amphetamine-type stimulant, it is the second most commonly used illicit drug worldwide. Outside of governmental sources, few studies have examined... (Source: SafetyLit)
Source: SafetyLit - June 18, 2018 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Crisis under the radar: illicit amphetamine use is reaching epidemic proportions and contributing to resource over-utilization at a level 1 trauma center - Gemma VA, Chapple KA, Goslar PW, Israr S, Petersen SR, Weinberg JA.
INTRODUCTION: Trauma centers reported illicit amphetamine use in approximately 10% of trauma admissions in the previous decade. From experience at a trauma center located in a southwestern metropolis, our perception is that illicit amphetamine use is on th... (Source: SafetyLit)
Source: SafetyLit - May 24, 2018 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Huge surge in kids poisoned by ADHD pills since 2000
Between 2000 and 2014, around 10,000 American children under 19 were hospitalized, and three died after taking methylphenidate or amphetamine, a new study reveals. (Source: the Mail online | Health)
Source: the Mail online | Health - May 21, 2018 Category: Consumer Health News Source Type: news

Unnecessary And Accidental Use Of ADHD Drugs Increases Over 60%, Study Suggests
(CNN) — Exposure to common medications used to treat attention deficit hyperactivity disorder has increased by more than 60% in US children and adolescents, according to a new study. The study, published Monday in the journal Pediatrics, looked at all calls to US poison control centers for unintentional or intentional exposure to ADHD medications between 2000 and 2014 among children and adolescents. The researchers found that the number of calls increased from 7,018 in 2000 to 11,486 in 2014 — a 64% increase. According to the study’s authors, “exposure” refers to the unnecessary ingestion, inh...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - May 21, 2018 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health ADHD Local TV Source Type: news

Dark classics in chemical neuroscience: "cathinone-derived psychostimulants" - Simmons SJ, Leyrer-Jackson JM, Oliver CF, Hicks C, Muschamp J, Rawls SM, Olive MF.
Cathinone is a plant alkaloid found in khat leaves of perennial shrubs grown in East Africa. Similar to cocaine, cathinone elicits psychostimulant effects which are in part attributed to its amphetamine-like structure. Around 2010, home laboratories began ... (Source: SafetyLit)
Source: SafetyLit - May 3, 2018 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Substance Use Disorders Linked to Conversion to Schizophrenia
Cannabis, amphetamine, opioid use disorders all linked to conversion from schizotypal disorder (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - April 26, 2018 Category: Psychiatry Tags: Psychiatry, Journal, Source Type: news

Cannabis Use Tied to Schizophrenia Conversion (CME/CE)
(MedPage Today) -- Similar links found with amphetamine and opioid abuse (Source: MedPage Today Pediatrics)
Source: MedPage Today Pediatrics - April 25, 2018 Category: Pediatrics Source Type: news

Predictive factors of mortality in acute amphetamine type stimulants poisoning; a review of 226 cases - Rahimi M, Lookzadeh S, Sadeghi R, Soltaninejad K, Shadnia S, Pajoumand A, Hassanian-Moghaddam H, Zamani N, Latifi-Pour M.
In this study we aimed to define the predictive factors of mortality in acute ATS poisoning patient... (Source: SafetyLit)
Source: SafetyLit - March 8, 2018 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Cross-sectional cause of death comparisons for stimulant and opioid mortality in San Francisco, 2005-2015 - Turner C, Chandrakumar D, Rowe C, Santos GM, Riley ED, Coffin PO.
BACKGROUND: Opioids and stimulants (e.g., cocaine or methamphetamine/amphetamine [MAMP]) are major contributors to acute substance toxicity deaths. Causes of stimulant death have received little attention. We sought to characterize and compare causes of de... (Source: SafetyLit)
Source: SafetyLit - March 1, 2018 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Comparison of concentrations of drugs between blood samples with and without fluoride additive —important findings for Δ9-tetrahydrocannabinol and amphetamine - Wiedfeld C, Krueger J, Skopp G, Musshoff F.
Fluoride is a common stabilizing agent in forensic toxicology to avoid the frequent problem of degradation of drugs in blood samples especially described for cocaine. In cases only samples with addition of fluoride are available, it is a crucial questio... (Source: SafetyLit)
Source: SafetyLit - February 19, 2018 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Amphetamine abuse disrupts development of mouse prefrontal cortex
(Society for Neuroscience) Recreational drug use during adolescence may disrupt development of an understudied part of the prefrontal cortex, according to a study of male mice published in eNeuro. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - January 8, 2018 Category: International Medicine & Public Health Source Type: news

Discordant reporting of nonmedical amphetamine use among Adderall-using high school seniors in the US - Palamar JJ, Le A.
BACKGROUND: Amphetamine is the most prevalent prescription stimulant in the United States, both medically and nonmedically. Reliable data on nonmedical use is needed to continue to inform prevention. To determine whether adolescents accurately self-report ... (Source: SafetyLit)
Source: SafetyLit - November 6, 2017 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

ADHD Drug Misuse A Part of Teen Amphetamine Abuse
That could lead to an undercount of the extent of the problem, researchers say (Source: WebMD Health)
Source: WebMD Health - October 25, 2017 Category: Consumer Health News Source Type: news

Adderall Misuse May Be Hidden Part of Teen Amphetamine Abuse
That could lead to an undercount of the extent of the problem, researchers say Source: HealthDay Related MedlinePlus Pages: Teen Health (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - October 25, 2017 Category: Consumer Health News Source Type: news

Adderall Misuse May Be Hidden Part of Teen Amphetamine Abuse
WEDNESDAY, Oct. 25, 2017 -- American teens underestimate their use of amphetamines, likely because many don't know that the attention-deficit/hyperactivity disorder (ADHD) drug Adderall is an amphetamine, a new study suggests. High school and... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - October 25, 2017 Category: General Medicine Source Type: news

Teens unaware Adderall is an amphetamine, underreport use
A new study is highlighting a problem with teenagers, the underrporting of amphetamine use mainly due to lack of knowledge of which drugs are amphetamines. (Source: Health News - UPI.com)
Source: Health News - UPI.com - October 23, 2017 Category: Consumer Health News Source Type: news

Adolescents underreport amphetamine use, likely unaware that adderall is amphetamine
(New York University) High school seniors appear to be underreporting their nonmedical use of amphetamine, despite reporting using Adderall without a doctor's orders, finds a study by the Center for Drug Use and HIV/HCV Research (CDUHR) at NYU Meyers College of Nursing. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - October 23, 2017 Category: International Medicine & Public Health Source Type: news

Can a Pumpkin-Shaped Molecule Bring a Different Ending to "Breaking Bad"?
Speed, uppers, chalk, glass, crystal, or whatever you prefer to call them, can be instantly detected from biological fluids with a new portable kit that costs as little as $50. Scientists at the Center for Self-Assembly and Complexity, within the Institute for Basic Science (IBS, South Korea), in collaboration with Pohang University of Science and Technology (POSTECH), have devised the first methamphetamine and amphetamine sensor that can detect minute concentrations of these drugs from a single drop of urine in real-time. (Source: eHealth News EU)
Source: eHealth News EU - September 28, 2017 Category: Information Technology Tags: Featured Research Research and Development Source Type: news

Can a pumpkin-shaped molecule bring a different ending to 'Breaking Bad'?
(Institute for Basic Science) A cheap, sensitive, real-time meth and amphetamine drug detector wristband connected to a smartphone app could become the new alcohol breathalyzer. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - September 28, 2017 Category: International Medicine & Public Health Source Type: news

Adzenys ER (Amphetamine Extended-Release Oral Suspension) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 27, 2017 Category: Drugs & Pharmacology Source Type: news

Organic psychosis and nystagmus? consider dextromethorphan toxicity
2 out of 5 stars Dextromethorphan in Cough Syrup: The Poor Man’s Psychosis. Martinak B et al. Psychopharmacol Bull 2017 Sep 15:47:59-63. Full Text Dextromethorphan (DXM) is found in many over-the-counter cough and cold medications. At recommended therapeutic dosage (up to 120 mg per day in divided doses) DXM is safe and has no psychiatric effects. However, DXM and its major metabolite —dextrorphan — act as NMDA receptor antagonists, producing effects similar to those of phencyclidine (PCP) or ketamine when taken in large amounts. The intensity of psychiatric symptoms seen after DXM overdose...
Source: The Poison Review - September 26, 2017 Category: Toxicology Authors: Leon Gussow Tags: Medical cough and cold medicine dextromethorphan ketamine over-the-counter phencyclidine Source Type: news

FDA Clears Liquid Extended-Release Amphetamine for ADHD FDA Clears Liquid Extended-Release Amphetamine for ADHD
Adzenys ER, a liquid extended-release amphetamine product, is another treatment option for patients aged 6 years and older with attention-deficit/hyperactivity disorder (ADHD).FDA Approvals (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 19, 2017 Category: Consumer Health News Tags: Psychiatry News Alert Source Type: news

Escalating patterns of emergency health care prior to first admission with amphetamine psychosis: A window of opportunity? - Sara G, Lappin J, Dobbins T, Dunlop AJ, Degenhardt L.
AIM: To describe health service contact in the two years prior to a first hospital admission with amphetamine-related psychosis, and to identify possible opportunities for early intervention. METHOD: Routine health data collections were used to ide... (Source: SafetyLit)
Source: SafetyLit - September 16, 2017 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Neos Therapeutics Receives U.S. FDA Approval of Adzenys ER (amphetamine) Extended-Release Oral Suspension for ADHD
DALLAS and FORT WORTH, Texas, Sept. 15, 2017 (GLOBE NEWSWIRE) -- Neos Therapeutics, Inc. (Nasdaq:NEOS), a pharmaceutical company focused on developing, manufacturing and commercializing innovative extended-release products using its proprietary... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - September 15, 2017 Category: Drugs & Pharmacology Source Type: news

The prognosis following amphetamine poisoning - Horwitz H, Dalhoff KP, Klemp M, Horwitz A, Andersen JT, J ürgens G.
This study investigated the long-term mortality following poisoning by amphetamine or substituted amphetamines. Furthermore, we examined the social problems and somatic and psychiatric co-morbidity related to amphetamine poisoning, and their impact o... (Source: SafetyLit)
Source: SafetyLit - August 24, 2017 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Amphetamine combo linked to Islamic State more potent than thought
LONDON, Aug 16 (Reuters) - A synthetic psychoactive drug linked to substance abuse in the Middle East and said to be a fund-raising tool and stimulant for Islamist militants is more dangerous than previously thought, scientists said on Wednesday. (Source: Reuters: Health)
Source: Reuters: Health - August 16, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

August 2017 RxNorm Release Available for Download
The August 2017 RxNorm Release is now available for download. The August release includes over 15 new 2017-2018 flu vaccine concepts and a new Qualitative Distinction “3-Bead” to distinguish amphetamine products which are not interchangeable. (Source: UMLS News)
Source: UMLS News - August 7, 2017 Category: Databases & Libraries Source Type: news

Methamphetamine : epidemiology, clinical importance and sequelae of abuse - Arnaud N, Thomasius T.
Methamphetamine (also known as meth and crystal meth) is a  highly psychoactive synthetic amphetamine type stimulant, which falls under the German Federal Narcotics Law. The substance is similar to other stimulants but has distinct features with respect to... (Source: SafetyLit)
Source: SafetyLit - July 24, 2017 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Mixed-amphetamine salts expectancies among college students: is stimulant induced cognitive enhancement a placebo effect? - Cropsey KL, Schiavon S, Hendricks PS, Froelich M, Lentowicz I, Fargason R.
INTRODUCTION: Non-medical use of prescription stimulants for cognitive enhancement in college students is increasing, despite evidence showing little benefit in non-clinical populations. The balanced placebo design (BPD) was used to independently evaluate ... (Source: SafetyLit)
Source: SafetyLit - July 15, 2017 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Morning administration of oral methamphetamine dose-dependently disrupts nighttime sleep in recreational stimulant users - Herrmann ES, Johnson PS, Bruner NR, Vandrey R, Johnson MW.
INTRODUCTION: Use of amphetamine-type stimulants (e.g., methamphetamine) is associated with acute sleep disruptions. No prior reports have characterized the acute effects of methamphetamine on sleep using polysomnography, the gold standard for objective sl... (Source: SafetyLit)
Source: SafetyLit - July 15, 2017 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Discrimination between drug abuse and medical therapy: case report of a tranylcypromine overdose-related fatality - Akhgari M, Jokar F, Etemadi-Aleagha A, Ghasemi A.
Tranylcypromine is an effective antidepressant from the class of monoamine oxidase inhibitors and is structurally related to amphetamine. However, reports differ regarding the potential metabolism of tranylcypromine to amphetamine and methamphetamine withi... (Source: SafetyLit)
Source: SafetyLit - July 14, 2017 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Study: Most ADHD medications aren't associated with risk of irritability
Irritability is common across psychiatric diagnoses, but is especially common in children with ADHD. Some common ADHD medications are purported to increase irritability, leading doctors and families to avoid them, even though medication is a highly effective treatment. However, a Yale study found that only amphetamine-derived medications were associated with an increase in irritability. Methylphenidates were not. (Source: Yale Science and Health News)
Source: Yale Science and Health News - July 13, 2017 Category: Universities & Medical Training Source Type: news

Mydayis (Mixed Salts of a Single-entity Amphetamine Product Capsules) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - June 28, 2017 Category: Drugs & Pharmacology Source Type: news

The addition of amphetamine to potentially sedating medication regimens: an exploratory investigation of the impact upon reaction time and sustained attention - Price JW.
OBJECTIVES: The addition of amphetamine to a sedating medication may reduce sedation but does it augment reaction time and sustained attention for workers? The purpose of this exploratory study was gain insight into between group differences that would ass... (Source: SafetyLit)
Source: SafetyLit - June 24, 2017 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Shire receives FDA approval for Mydayis to treat attention deficit hyperactivity disorder
Biotechnology company Shire has received the US Food and Drug Administration (FDA) approval for Mydayis (mixed salts of a single-entity amphetamine product) for the treatment of attention deficit hyperactivity disorder (ADHD). (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - June 21, 2017 Category: Pharmaceuticals Source Type: news

Another extended-release ADHD drug wins FDA nod
Days after Neos Therapeutics (NSDQ:NEOS) nabbed U.S. regulatory approval for its controlled-release formulation of methylphenidate, Shire (NSDQ:SHPG) said it won a nod from the FDA for its long-acting ADHD drug. The drug, Mydayis, is made up of the same active ingredient in Shire’s ADHD treatment Adderall XR – amphetamine – but it is designed to last up to 16 hours. Adderall XR is formulated to control symptoms in patients for up to 12 hours. Get the full story at our sister site, Drug Delivery Business News. The post Another extended-release ADHD drug wins FDA nod appeared first on MassDev...
Source: Mass Device - June 21, 2017 Category: Medical Devices Authors: Sarah Faulkner Tags: Food & Drug Administration (FDA) Neurological Pharmaceuticals Regulatory/Compliance Wall Street Beat neostherapeutics Shire Plc. Source Type: news

FDA Clears Long-Acting ADHD Drug Mydayis FDA Clears Long-Acting ADHD Drug Mydayis
Mydayis (mixed salts of amphetamine) is formulated to last up to 16 hours and is approved for adults and children aged 13 years and older.News Alerts (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 21, 2017 Category: Consumer Health News Tags: Psychiatry News Alert Source Type: news

FDA Approves Mydayis (mixed salts of a single-entity amphetamine product) – A New Once-Daily Option for ADHD
Lexington, Mass., USA – June 20, 2017 – Shire plc (LSE: SHP, NASDAQ: SHPG) announced today that the U.S. Food and Drug Administration (FDA) has approved Mydayis (mixed salts of a single-entity amphetamine product), a once-daily treatment... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - June 21, 2017 Category: Drugs & Pharmacology Source Type: news

Dyanavel XR (Amphetamine Extended-release Oral Suspension) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - May 25, 2017 Category: Drugs & Pharmacology Source Type: news

Medico-legal assessment of methamphetamine and amphetamine serum concentrations-what can we learn from survived intoxications? - Weber M, Lessig R, Richter C, Ritter AP, Wei ß I.
Medico-legal experts are increasingly enlisted to assess the methamphetamine and amphetamine serum concentrations after a criminal offense. However, since criminal users rarely provide useful information to medico-legal experts regarding the substances abu... (Source: SafetyLit)
Source: SafetyLit - May 19, 2017 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

The forensic implications of amphetamine intoxication in cases of inflicted blunt craniocerebral trauma - Byard RW, Donkin J, Vink R.
The effects of D-amphetamine on outcome after blunt craniocerebral trauma are characterized and the potential legal implications discussed. Traumatic brain injury (TBI) was induced under general anesthesia in adult, male Sprague Dawley rats using the impac... (Source: SafetyLit)
Source: SafetyLit - April 11, 2017 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

San Diego Debuts Mouth Swabs To Detect Drivers High On Pot
A major concern of police about state laws legalizing marijuana has been how to detect when motorists may be driving under the influence of pot — or other drugs. Now San Diego police are joining a growing number of cities relying on mouth swabs for chemical tests to detect drugs in drivers. The swabs and two portable testing machines hit the field Friday night in San Diego, reported CBS-8 TV. It’s the second city in the state after Los Angeles to use the new detection method. The machines test for the presence of marijuana and six other drugs: cocaine, methamphetamine, amphetamine, methadone, opiates and benzod...
Source: Science - The Huffington Post - March 19, 2017 Category: Science Source Type: news

Pharmacological and non-pharmacological treatment of adults with ADHD: a meta-review
In conclusion, while available evidence addressed mainly the efficacy and tolerability of psychostimulants and non-psychostimulants for ADHD core symptoms in the short term, we still need further empirical support for the non-pharmacological and multimodal treatments. A comprehensive evidence-informed hierarchy of ADHD drugs based on their efficacy and tolerability is not yet available but it should be the next research priority in the field. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - March 16, 2017 Category: Consumer Health News Source Type: news

Khat in the Horn of Africa: A Scourge or Blessing?
Men lounging in Dire Dawa’s Chattara Market chewing khat, Ethiopia. Credit: James Jeffrey/IPSBy James JeffreyADDIS ABABA, Mar 12 2017 (IPS)Throughout a Sunday afternoon in the Ethiopian capital, Yemeni émigré men in their fifties and sixties arrive at a traditional Yemeni-styled mafraj room clutching bundles of green, leafy stalks: khat.As the hours pass they animatedly discuss economics, politics, history, life and more while chewing the leaves. The gathering is a picture of civility. But in many countries khat has a bad reputation, with it either being banned or prompting calls for it to be banned.&nb...
Source: IPS Inter Press Service - Health - March 12, 2017 Category: Global & Universal Authors: James Jeffrey Tags: Africa Development & Aid Economy & Trade Featured Food & Agriculture Headlines Health Population Ethiopia khat Somalia Somaliland Source Type: news

Medical News Today: Amphetamine use may 'speed up' heart aging
Using amphetamines may accelerate aging of the heart, suggest researchers. They emphasize that stimulant abusers do physiological and cardiovascular harm. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 11, 2017 Category: Consumer Health News Tags: Alcohol / Addiction / Illegal Drugs Source Type: news

Amphetamine abuse abuses the heart
HealthDay News Using illegal amphetamine drugs such as " speed " and " ice " may lead to premature aging of the arteries and heart, researchers warn. (Source: Health News - UPI.com)
Source: Health News - UPI.com - February 10, 2017 Category: Consumer Health News Source Type: news

Amphetamine Abuse Abuses the Heart
Study finds arteries of recreational users look older than their years (Source: WebMD Health)
Source: WebMD Health - February 10, 2017 Category: Consumer Health News Source Type: news

Amphetamine Abuse Abuses the Heart
FRIDAY, Feb. 10, 2017 -- Using illegal amphetamine drugs such as " speed " and " ice " may lead to premature aging of the arteries and heart, researchers warn. They said their new study adds to evidence about the need to tackle the " global stimulant... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - February 10, 2017 Category: Journals (General) Source Type: news