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Escalating patterns of emergency health care prior to first admission with amphetamine psychosis: A window of opportunity? - Sara G, Lappin J, Dobbins T, Dunlop AJ, Degenhardt L.
AIM: To describe health service contact in the two years prior to a first hospital admission with amphetamine-related psychosis, and to identify possible opportunities for early intervention. METHOD: Routine health data collections were used to ide... (Source: SafetyLit)
Source: SafetyLit - September 16, 2017 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Neos Therapeutics Receives U.S. FDA Approval of Adzenys ER (amphetamine) Extended-Release Oral Suspension for ADHD
DALLAS and FORT WORTH, Texas, Sept. 15, 2017 (GLOBE NEWSWIRE) -- Neos Therapeutics, Inc. (Nasdaq:NEOS), a pharmaceutical company focused on developing, manufacturing and commercializing innovative extended-release products using its proprietary... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - September 15, 2017 Category: Drugs & Pharmacology Source Type: news

The prognosis following amphetamine poisoning - Horwitz H, Dalhoff KP, Klemp M, Horwitz A, Andersen JT, J ürgens G.
This study investigated the long-term mortality following poisoning by amphetamine or substituted amphetamines. Furthermore, we examined the social problems and somatic and psychiatric co-morbidity related to amphetamine poisoning, and their impact o... (Source: SafetyLit)
Source: SafetyLit - August 24, 2017 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Amphetamine combo linked to Islamic State more potent than thought
LONDON, Aug 16 (Reuters) - A synthetic psychoactive drug linked to substance abuse in the Middle East and said to be a fund-raising tool and stimulant for Islamist militants is more dangerous than previously thought, scientists said on Wednesday. (Source: Reuters: Health)
Source: Reuters: Health - August 16, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

August 2017 RxNorm Release Available for Download
The August 2017 RxNorm Release is now available for download. The August release includes over 15 new 2017-2018 flu vaccine concepts and a new Qualitative Distinction “3-Bead” to distinguish amphetamine products which are not interchangeable. (Source: UMLS News)
Source: UMLS News - August 7, 2017 Category: Databases & Libraries Source Type: news

Methamphetamine : epidemiology, clinical importance and sequelae of abuse - Arnaud N, Thomasius T.
Methamphetamine (also known as meth and crystal meth) is a  highly psychoactive synthetic amphetamine type stimulant, which falls under the German Federal Narcotics Law. The substance is similar to other stimulants but has distinct features with respect to... (Source: SafetyLit)
Source: SafetyLit - July 24, 2017 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Mixed-amphetamine salts expectancies among college students: is stimulant induced cognitive enhancement a placebo effect? - Cropsey KL, Schiavon S, Hendricks PS, Froelich M, Lentowicz I, Fargason R.
INTRODUCTION: Non-medical use of prescription stimulants for cognitive enhancement in college students is increasing, despite evidence showing little benefit in non-clinical populations. The balanced placebo design (BPD) was used to independently evaluate ... (Source: SafetyLit)
Source: SafetyLit - July 15, 2017 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Morning administration of oral methamphetamine dose-dependently disrupts nighttime sleep in recreational stimulant users - Herrmann ES, Johnson PS, Bruner NR, Vandrey R, Johnson MW.
INTRODUCTION: Use of amphetamine-type stimulants (e.g., methamphetamine) is associated with acute sleep disruptions. No prior reports have characterized the acute effects of methamphetamine on sleep using polysomnography, the gold standard for objective sl... (Source: SafetyLit)
Source: SafetyLit - July 15, 2017 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Discrimination between drug abuse and medical therapy: case report of a tranylcypromine overdose-related fatality - Akhgari M, Jokar F, Etemadi-Aleagha A, Ghasemi A.
Tranylcypromine is an effective antidepressant from the class of monoamine oxidase inhibitors and is structurally related to amphetamine. However, reports differ regarding the potential metabolism of tranylcypromine to amphetamine and methamphetamine withi... (Source: SafetyLit)
Source: SafetyLit - July 14, 2017 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Study: Most ADHD medications aren't associated with risk of irritability
Irritability is common across psychiatric diagnoses, but is especially common in children with ADHD. Some common ADHD medications are purported to increase irritability, leading doctors and families to avoid them, even though medication is a highly effective treatment. However, a Yale study found that only amphetamine-derived medications were associated with an increase in irritability. Methylphenidates were not. (Source: Yale Science and Health News)
Source: Yale Science and Health News - July 13, 2017 Category: Universities & Medical Training Source Type: news

Mydayis (Mixed Salts of a Single-entity Amphetamine Product Capsules) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - June 28, 2017 Category: Drugs & Pharmacology Source Type: news

The addition of amphetamine to potentially sedating medication regimens: an exploratory investigation of the impact upon reaction time and sustained attention - Price JW.
OBJECTIVES: The addition of amphetamine to a sedating medication may reduce sedation but does it augment reaction time and sustained attention for workers? The purpose of this exploratory study was gain insight into between group differences that would ass... (Source: SafetyLit)
Source: SafetyLit - June 24, 2017 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Shire receives FDA approval for Mydayis to treat attention deficit hyperactivity disorder
Biotechnology company Shire has received the US Food and Drug Administration (FDA) approval for Mydayis (mixed salts of a single-entity amphetamine product) for the treatment of attention deficit hyperactivity disorder (ADHD). (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - June 21, 2017 Category: Pharmaceuticals Source Type: news

Another extended-release ADHD drug wins FDA nod
Days after Neos Therapeutics (NSDQ:NEOS) nabbed U.S. regulatory approval for its controlled-release formulation of methylphenidate, Shire (NSDQ:SHPG) said it won a nod from the FDA for its long-acting ADHD drug. The drug, Mydayis, is made up of the same active ingredient in Shire’s ADHD treatment Adderall XR – amphetamine – but it is designed to last up to 16 hours. Adderall XR is formulated to control symptoms in patients for up to 12 hours. Get the full story at our sister site, Drug Delivery Business News. The post Another extended-release ADHD drug wins FDA nod appeared first on MassDev...
Source: Mass Device - June 21, 2017 Category: Medical Devices Authors: Sarah Faulkner Tags: Food & Drug Administration (FDA) Neurological Pharmaceuticals Regulatory/Compliance Wall Street Beat neostherapeutics Shire Plc. Source Type: news

FDA Clears Long-Acting ADHD Drug Mydayis FDA Clears Long-Acting ADHD Drug Mydayis
Mydayis (mixed salts of amphetamine) is formulated to last up to 16 hours and is approved for adults and children aged 13 years and older.News Alerts (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 21, 2017 Category: Consumer Health News Tags: Psychiatry News Alert Source Type: news

FDA Approves Mydayis (mixed salts of a single-entity amphetamine product) – A New Once-Daily Option for ADHD
Lexington, Mass., USA – June 20, 2017 – Shire plc (LSE: SHP, NASDAQ: SHPG) announced today that the U.S. Food and Drug Administration (FDA) has approved Mydayis (mixed salts of a single-entity amphetamine product), a once-daily treatment... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - June 21, 2017 Category: Drugs & Pharmacology Source Type: news

Dyanavel XR (Amphetamine Extended-release Oral Suspension) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - May 25, 2017 Category: Drugs & Pharmacology Source Type: news

Medico-legal assessment of methamphetamine and amphetamine serum concentrations-what can we learn from survived intoxications? - Weber M, Lessig R, Richter C, Ritter AP, Wei ß I.
Medico-legal experts are increasingly enlisted to assess the methamphetamine and amphetamine serum concentrations after a criminal offense. However, since criminal users rarely provide useful information to medico-legal experts regarding the substances abu... (Source: SafetyLit)
Source: SafetyLit - May 19, 2017 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

The forensic implications of amphetamine intoxication in cases of inflicted blunt craniocerebral trauma - Byard RW, Donkin J, Vink R.
The effects of D-amphetamine on outcome after blunt craniocerebral trauma are characterized and the potential legal implications discussed. Traumatic brain injury (TBI) was induced under general anesthesia in adult, male Sprague Dawley rats using the impac... (Source: SafetyLit)
Source: SafetyLit - April 11, 2017 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

San Diego Debuts Mouth Swabs To Detect Drivers High On Pot
A major concern of police about state laws legalizing marijuana has been how to detect when motorists may be driving under the influence of pot — or other drugs. Now San Diego police are joining a growing number of cities relying on mouth swabs for chemical tests to detect drugs in drivers. The swabs and two portable testing machines hit the field Friday night in San Diego, reported CBS-8 TV. It’s the second city in the state after Los Angeles to use the new detection method. The machines test for the presence of marijuana and six other drugs: cocaine, methamphetamine, amphetamine, methadone, opiates and benzod...
Source: Science - The Huffington Post - March 19, 2017 Category: Science Source Type: news

Pharmacological and non-pharmacological treatment of adults with ADHD: a meta-review
In conclusion, while available evidence addressed mainly the efficacy and tolerability of psychostimulants and non-psychostimulants for ADHD core symptoms in the short term, we still need further empirical support for the non-pharmacological and multimodal treatments. A comprehensive evidence-informed hierarchy of ADHD drugs based on their efficacy and tolerability is not yet available but it should be the next research priority in the field. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - March 16, 2017 Category: Consumer Health News Source Type: news

Khat in the Horn of Africa: A Scourge or Blessing?
Men lounging in Dire Dawa’s Chattara Market chewing khat, Ethiopia. Credit: James Jeffrey/IPSBy James JeffreyADDIS ABABA, Mar 12 2017 (IPS)Throughout a Sunday afternoon in the Ethiopian capital, Yemeni émigré men in their fifties and sixties arrive at a traditional Yemeni-styled mafraj room clutching bundles of green, leafy stalks: khat.As the hours pass they animatedly discuss economics, politics, history, life and more while chewing the leaves. The gathering is a picture of civility. But in many countries khat has a bad reputation, with it either being banned or prompting calls for it to be banned.&nb...
Source: IPS Inter Press Service - Health - March 12, 2017 Category: Global & Universal Authors: James Jeffrey Tags: Africa Development & Aid Economy & Trade Featured Food & Agriculture Headlines Health Population Ethiopia khat Somalia Somaliland Source Type: news

Medical News Today: Amphetamine use may 'speed up' heart aging
Using amphetamines may accelerate aging of the heart, suggest researchers. They emphasize that stimulant abusers do physiological and cardiovascular harm. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 11, 2017 Category: Consumer Health News Tags: Alcohol / Addiction / Illegal Drugs Source Type: news

Amphetamine abuse abuses the heart
HealthDay News Using illegal amphetamine drugs such as " speed " and " ice " may lead to premature aging of the arteries and heart, researchers warn. (Source: Health News - UPI.com)
Source: Health News - UPI.com - February 10, 2017 Category: Consumer Health News Source Type: news

Amphetamine Abuse Abuses the Heart
Study finds arteries of recreational users look older than their years (Source: WebMD Health)
Source: WebMD Health - February 10, 2017 Category: Consumer Health News Source Type: news

Amphetamine Abuse Abuses the Heart
FRIDAY, Feb. 10, 2017 -- Using illegal amphetamine drugs such as " speed " and " ice " may lead to premature aging of the arteries and heart, researchers warn. They said their new study adds to evidence about the need to tackle the " global stimulant... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - February 10, 2017 Category: Journals (General) Source Type: news

Speed, Ecstasy Accelerate Heart Aging
(MedPage Today) -- Amphetamine abuse may add more years to the heart than tobacco (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - February 10, 2017 Category: Psychiatry Source Type: news

Evekeo (Amphetamine Sulfate Tablets, USP) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - January 23, 2017 Category: Drugs & Pharmacology Source Type: news

Neuropharmacology of new psychoactive substances (nps): focus on the rewarding and reinforcing properties of cannabimimetics and amphetamine-like stimulants - Miliano C, Serpelloni G, Rimondo C, Mereu M, Marti M, De Luca MA.
New psychoactive substances (NPS) are a heterogeneous and rapidly evolving class of molecules available on the global illicit drug market (e.g smart shops, internet, "dark net") as a substitute for controlled substances. The use of NPS, mainly consumed alo... (Source: SafetyLit)
Source: SafetyLit - January 20, 2017 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

Adderall (Amphetamine, Dextroamphetamine Mixed Salts) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - January 20, 2017 Category: Drugs & Pharmacology Source Type: news

Indirect chiral separation of 8 novel amphetamine derivatives as potential new psychoactive compounds by GC-MS and HPLC - Wei ß JA, Kadkhodaei K, Schmid MG.
Amphetamine and its derivatives gained high popularity on the illegal drug market. In the last few years, a lot of new psychoactive compounds structurally related to amphetamine, such as 4-fluoroamphetamine and 4-fluoromethamphetamine swamped the drug mark... (Source: SafetyLit)
Source: SafetyLit - January 14, 2017 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

Dextroamphetamine Saccharate, Amphetamine Aspartate Monohydrate, Dextroamphetamine Sulfate and Amphetamine Sulfate Tablets (New - Discontinuation)
Updated Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - January 5, 2017 Category: Drugs & Pharmacology Source Type: news

Amphetamine Orally Disintegrating Tablets for ADHD Amphetamine Orally Disintegrating Tablets for ADHD
A newly approved extended-release orally disintegrating amphetamine tablet may be another option for the treatment of ADHD.Pediatric Pharmacotherapy (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 4, 2017 Category: Consumer Health News Tags: Pediatrics Journal Article Source Type: news

Timing of amphetamine exposure in relation to puberty onset determines its effects on anhedonia, exploratory behavior, and dopamine D1 receptor expression in young adulthood - Kang S, Wu MM, Galvez R, Gulley JM.
Non-medical use of amphetamine (AMPH) among adolescents is prevalent, which is problematic given the potential consequences of developmental drug exposure on brain function and behavior. Previously we found in adult male rats that AMPH exposure starting be... (Source: SafetyLit)
Source: SafetyLit - December 30, 2016 Category: Global & Universal Tags: Age: Adolescents Source Type: news

Adderall XR (Amphetamine, Dextroamphetamine Mixed Salts) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 24, 2016 Category: Drugs & Pharmacology Source Type: news

French rarely medicate children for ADHD, treat underlying conditions
(NaturalNews) Attention Deficit Hyperactivity Disorder (ADHD) is a well known medical term in America, but in France, it’s rarely used, if ever. That’s because doctors in France address behavioral issues in children holistically, not as a condition that can be drugged out of them. ADHD is a predatory label, used to force nefarious amphetamine drugs... (Source: NaturalNews.com)
Source: NaturalNews.com - December 14, 2016 Category: Consumer Health News Source Type: news

"Bath salts" the New York City Medical Examiner experience: a 3-year retrospective review - Deroux SJ, Dunn WA.
"Bath salts" are synthetic derivatives of cathinones, compounds found in the leaves of Catha edulis, which possesses amphetamine-like properties. At the New York City Office of Chief Medical Examiner, we conducted a 3-year retrospective analysis of deaths ... (Source: SafetyLit)
Source: SafetyLit - December 9, 2016 Category: Global & Universal Tags: Age: Adolescents Source Type: news

Adzenys XR-ODT (Amphetamine Extended-release Orally Disintegrating Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 1, 2016 Category: Drugs & Pharmacology Source Type: news

Amphetamine may slow rise of body temperature, mask fatigue to enhance endurance, study finds
Amphetamine may slow down the rise of temperature in the body and mask fatigue, which could allow athletes to run significantly longer but result in potentially dangerous overheating of muscles, according to a study. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - November 29, 2016 Category: Science Source Type: news

Amphetamine may slow rise of body temperature and mask fatigue to enhance endurance, study finds
(Georgia State University) Amphetamine may slow down the rise of temperature in the body and mask fatigue, which could allow athletes to run significantly longer but result in potentially dangerous overheating of muscles, according to a study. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 29, 2016 Category: Global & Universal Source Type: news

Scripps Florida scientists pinpoint regulator of amphetamine induced motor activity
In new findings that could have an impact on the development of therapies for a number of currently untreatable brain disorders such as Parkinson's and Huntington's diseases, scientists from the... (Source: Parkinson's Disease News From Medical News Today)
Source: Parkinson's Disease News From Medical News Today - November 21, 2016 Category: Neurology Tags: Parkinson's Disease Source Type: news

Neos Therapeutics Submits NDA for Amphetamine Extended-Release Liquid Suspension Drug Candidate, NT-0201, for the Treatment of ADHD
DALLAS/FORT WORTH, Texas, Nov. 17, 2016 (GLOBE NEWSWIRE) -- Neos Therapeutics, Inc. (NASDAQ:NEOS), a pharmaceutical company focused on developing and commercializing innovative extended-release (XR) products for the treatment of attention-deficit... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - November 17, 2016 Category: Drugs & Pharmacology Source Type: news

[Research Article] RasGRP1 promotes amphetamine-induced motor behavior through a Rhes interaction network ("Rhesactome") in the striatum
Protein interaction networks of the GTPase Rhes regulatemotor control in the striatum. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - November 17, 2016 Category: Science Authors: Neelam Shahani, Supriya Swarnkar, Vincenzo Giovinazzo, Jenny Morgenweck, Laura M. Bohn, Catherina Scharager-Tapia, Bruce Pascal, Pablo Martinez-Acedo, Kshitij Khare, Srinivasa Subramaniam Source Type: news

Scripps Florida scientists pinpoint regulator of amphetamine induced motor activity
(Scripps Research Institute) In new findings that could have an impact the development of therapies for a number of currently untreatable brain disorders such as Parkinson's and Huntington's diseases, scientists from the Florida campus of The Scripps Research Institute (TSRI) have found, for the first time, that a specific signaling circuit in the brain is deeply involved in motor activity. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 16, 2016 Category: Global & Universal Source Type: news

On-Site Drug Testing Cups target hotel industry.
Used for pre-employment screening, FDA-approved QuikScreen Drug Testing Cups detect drugs such as Amphetamine, Cocaine, Opiates, Tri-cyclic Antidepressant, Propoxyphene, and Methamphetamine in urine samples within 5 minutes. CLIA-waived products do not require any handling or manipulation to activate test. Providing 18-24 month shelf life, each cup includes temperature strip and identification label. Leak-proof design enables positive specimens to be shipped to laboratory for GC/MS...This story is related to the following:Urinalysis Equipment |Specimen Cups (Source: Industrial Newsroom - Health, Medical and Dental Supplies)
Source: Industrial Newsroom - Health, Medical and Dental Supplies - October 27, 2016 Category: Medical Equipment Source Type: news

The stigmatisation of 'ice' and under-reporting of meth/amphetamine use in general population surveys: a case study from Australia - Chalmers J, Lancaster K, Hughes C.
BACKGROUND AND AIMS: Stigmatisation of illicit drug use is known to discourage people from reporting their use of illicit drugs. In the context of Australia's two recent "ice-epidemics" this study examines whether rapid increases in community concern about... (Source: SafetyLit)
Source: SafetyLit - September 19, 2016 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

Ecological consequences of amphetamine pollution in urban streams
Pharmaceutical and illicit drugs are present in streams in Baltimore, Maryland. At some sites, amphetamine concentrations are high enough to alter the base of the aquatic food web. So reports a new study which is one of the first to explore the ecological consequences of stimulant pollution in urban streams. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - August 25, 2016 Category: Science Source Type: news

Medicolegal aspects of PMA-related deaths - Rojek S, Bolecha ła F, Kula K, Maciów-Głąb M, Kłys M.
Unlike amphetamine, amphetamine-like substances accessible on the drug market are less expensive and more easily available; they also produce hallucinogenic effects expected by the users. Such properties render them more attractive as compared to amphetami... (Source: SafetyLit)
Source: SafetyLit - August 12, 2016 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

Mindfulness training helpful in the recovery of adults addicted to stimulants
Meditation and other mindfulness strategies may reduce the likelihood of relapse for certain people struggling to break their addiction to stimulants including cocaine and methamphetamine, a UCLA study suggests. Results of the small clinical trial, published online this week in the journal Mindfulness, showed that mindfulness training is particularly beneficial for adults dependent on stimulants who have been diagnosed with depression or anxiety, common disorders among people with substance addiction. “When stimulant users attempt to quit, some of the most frequent complaints have to do with intolerable feelings of d...
Source: UCLA Newsroom: Health Sciences - August 5, 2016 Category: Universities & Medical Training Source Type: news

Near death from a novel synthetic opioid labeled U-47700: emergence of a new opioid class - Schneir A, Metushi IG, Sloane C, Benaron DJ, Fitzgerald RL.
BACKGROUND: In the last decade there has been a worldwide surge in the recreational abuse of novel psychoactive substances, particularly amphetamine derivatives and synthetic cannabinoids. Synthetic opioids such as AH-7921, MT-45, and U-47700, with structu... (Source: SafetyLit)
Source: SafetyLit - July 29, 2016 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news