Neuroanatomical Changes Underlying Vertical HIV Infection in Adolescents

Conclusion: This study found that HIV-infected pubertal children showed a delayed cortical maturation with atrophy. This abnormal pattern of cortical development may be the structural basis for cognitive impairment in HIV-infected children. Introduction Acquired immune deficiency syndrome (AIDS)-related encephalopathy is one of the most serious complications of AIDS and is more common in children than in adults (1). At present, there are nearly 2 million children living with human immunodeficiency virus (HIV) in the world, almost all newly infected children are infected through mother-to-child transmission (2). Effective antiretroviral therapy (ART) can significantly reduce mortality and the incidence of HIV encephalopathy (3). Although the children's HIV/AIDS has been transformed into chronic, controllable disease patterns, due to the HIV virus, antiretroviral drugs and a variety of environmental factors, a series of neuropsychological defects can still appear on HIV-infected (HIV+) children, sometimes even after the treatment has fully been accepted (4). Currently, some studies have reported and summarized the neurocognitive impairment and behavioral abnormality in children infected with HIV. For example, language barriers, delayed motor development, poor school performance, etc., and some may even have psychological problems such as anxiety and depression (5, 6). Although highly active antiretroviral therapy can improve the cognitive function of HIV+ childre...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research

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ConclusionIn the future, the survey is to be converted to a mobile accessible application and extended to the entire Paralympic Team.Level of evidence3
Source: Sports Orthopaedics and Traumatology - Category: Sports Medicine Source Type: research
This study constituted the second phase of a World Anti-Doping Agency (WADA) supported Social Science initiative.
Source: Performance Enhancement and Health - Category: Sports Medicine Source Type: research
Publication date: 1 October 2019Source: Personality and Individual Differences, Volume 148Author(s): Shuang Gao, Sander Thomaes, Wim Van Den Noortgate, Xiaochun Xie, Xiangkui Zhang, Suiping WangAbstractThe present study examined potential changes in narcissistic traits of Chinese youth from 2008 to 2017. A cross-temporal meta-analysis involving 29 independent samples (N = 14,795) found a downward temporal trend: Mean scores on the Narcissistic Personality Inventory and Narcissistic Personality Inventory for Chinese are significantly negatively associated with year of data collection, weighted by sample size (β =...
Source: Personality and Individual Differences - Category: Psychiatry & Psychology Source Type: research
Stats: state of residence: CA race: Asian (Chinese) undergrad: HYPSM major: Computer Science year: senior (taking 1 gap year) cGPA: 3.94 sGPA: 3.96 MCAT: 522 (130/131/129/132) ECs: research: my strongest EC, 2000+ hrs, 2pubs (1 first author, 1 fourth author), won some awards, researching full time during my gap year clinical volunteering: ~150hrs at free clinic, ~100hrs hrs at hospital nonclinical volunteering: started a nonprofit last year that I'll be growing in my gap year, ~200hrs... WAMC? + School List, MCAT: 522, GPA: 3.94, considering MD and MD-PhD
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: What Are My Chances? WAMC Medical Source Type: forums
This study attempts to highlight that females are still being negatively affected by existing gender stereotypes and prescribed gender identities despite relatively equal access and use of computer technology. This qualitative study aims to provide insights about the first-time user experience in a home environment of 16 middle school children in Turkey (8 males - 8 females), aged between 11 and 14 years, with a code learning game named “Code Combat”. The analysis is supported with complementary quantitative findings. The present study investigates the participants' conceptualizations and opinions toward coding...
Source: Computers in Human Behavior - Category: Information Technology Source Type: research
ConclusionOur study highlights the fact that mobile genetic elements, such as plasmids, IS1216E, Tn554 and Tn558, may facilitate the horizontal transmission of optrA or poxtA.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
ConclusionsOur work successfully identified the main active components in EXD, which could represent the efficacy of EXD on treating osteoporosis, and meanwhile, it also provided an effective strategy to investigate active ingredients from natural medicines, which might be helpful for drug development and application.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
The study helps explain what the brain is doing with all the energy it consumes. → Support PsyBlog for just $4 per month. Enables access to articles marked (M) and removes ads. → Explore PsyBlog's ebooks, all written by Dr Jeremy Dean: Accept Yourself: How to feel a profound sense of warmth and self-compassion The Anxiety Plan: 42 Strategies For Worry, Phobias, OCD and Panic Spark: 17 Steps That Will Boost Your Motivation For Anything Activate: How To Find Joy Again By Changing What You Do
Source: PsyBlog | Psychology Blog - Category: Psychiatry & Psychology Authors: Tags: Brain Health subscribers-only Source Type: blogs
People drinking this common beverage lost twice as much weight. → Support PsyBlog for just $4 per month. Enables access to articles marked (M) and removes ads. → Explore PsyBlog's ebooks, all written by Dr Jeremy Dean: Accept Yourself: How to feel a profound sense of warmth and self-compassion The Anxiety Plan: 42 Strategies For Worry, Phobias, OCD and Panic Spark: 17 Steps That Will Boost Your Motivation For Anything Activate: How To Find Joy Again By Changing What You Do
Source: PsyBlog | Psychology Blog - Category: Psychiatry & Psychology Authors: Tags: Weight Loss Source Type: blogs
Publication date: Available online 25 May 2019Source: American Heart JournalAuthor(s): Alexander C. Fanaroff, Amit N. Vora, Anita Y. Chen, Robin Mathews, Jacob A. Udell, Matthew T. Roe, Laine Thomas, Tracy Y. WangAbstractBackgroundLittle is known about the proportion of hospitals in the United States that offer clinical trial enrollment opportunities and how patient outcomes differ between hospitals that do and do not participate in clinical trials.MethodsIn the nationwide Chest Pain - MI registry, we described the proportion of hospitals that enrolled patients with acute myocardial infarction (MI) in clinical trials from ...
Source: American Heart Journal - Category: Cardiology Source Type: research
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