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Cell types underlying schizophrenia identified
(Karolinska Institutet) Scientists at Karolinska Institutet in Sweden and University of North Carolina, USA, have identified the cell types underlying schizophrenia in a new study published in Nature Genetics. The findings offer a roadmap for the development of new therapies to target the condition. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 21, 2018 Category: International Medicine & Public Health Source Type: news

fMRI shows a good word might tame psychosis
Researchers at the University of Missouri have found evidence in functional...Read more on AuntMinnie.comRelated Reading: fMRI shows dementia patients' brain response to music MRI of cortical folds may help predict psychosis fMRI offers clues about memory loss in older adults DTI-MRI poses new cause for schizophrenia fMRI shows LSD's adverse effects on the brain (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - May 17, 2018 Category: Radiology Source Type: news

Schizophrenics may do better with earlier, team-based care
(Reuters Health) - People with schizophrenia who are treated early in their disease course, with extra support in addition to drugs and psychotherapy, may do better than they would with usual treatment, which often lacks coordination and starts after psychosis has taken hold, a recent study suggests. (Source: Reuters: Health)
Source: Reuters: Health - May 16, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Are you feeding your brain the right nutrients? Folate, vitamins B12, C, E, and D are crucial for mental health
(Natural News) Feeding your brain the right nutrients, such as folate, and vitamins B12, C, E, and D are crucial for mental health. In a review, it was found that patients with the chronic mental disorder schizophrenia have low levels of these nutrients. A team of researchers from the University of Manchester, Belgium’s KU Leuven... (Source: NaturalNews.com)
Source: NaturalNews.com - May 11, 2018 Category: Consumer Health News Source Type: news

Predicting Psychosis Outside the Clinical High-Risk State Predicting Psychosis Outside the Clinical High-Risk State
This study evaluated the risk of developing emergent psychotic-disorders from clinical syndromes other than those usually considered at clinical high risk for psychosis.Schizophrenia Bulletin (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 11, 2018 Category: Consumer Health News Tags: Psychiatry Journal Article Source Type: news

The joy of neurons: A simplified 'cookbook' for engineering brain cells to study disease
(Scripps Research Institute) The new research opens the door to studying common brain conditions such as autism, schizophrenia, addiction and Alzheimer's disease under reproducible conditions in a dish. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 9, 2018 Category: International Medicine & Public Health Source Type: news

Karun Singh is the 2018 Canadian Association for Neuroscience Young Investigator awardee
(Canadian Association for Neuroscience) The Canadian Association for Neuroscience is proud to announce that Karun Singh (McMaster University) will receive the 2018 CAN Young Investigator Award on May 15th 2018 in Vancouver. Dr. Singh's research has broadened our understanding of the genetics of brain development, and of the risk factors underlying neurodevelopmental disorders. His work has uncovered new disease mechanisms for autism spectrum disorder and schizophrenia which are paving the way forward to identify new therapeutics. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - May 9, 2018 Category: International Medicine & Public Health Source Type: news

Creative people more at risk of schizophrenia, bipolar disorder and depression, huge study finds
A King's College study of Swedish medical records found those who studied subjects like music, drama or art at university have more psychiatric conditions than the general public. (Source: the Mail online | Health)
Source: the Mail online | Health - May 8, 2018 Category: Consumer Health News Source Type: news

AstraZeneca sells rights for Seroquel to Luye Pharma for $538 million
LONDON (Reuters) - British pharma company AstraZeneca said it had sold the rights for Seroquel, a treatment for schizophrenia and bipolar disease, to Luye Pharma Group for $538 million, as part of a strategy to focus on other therapy areas. (Source: Reuters: Health)
Source: Reuters: Health - May 8, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Increased mortality among people with schizophrenia and other non-affective psychotic disorders in the community: a systematic review and meta-analysis - Oakley P, Kisely S, Baxter A, Harris M, Desoe J, Dziouba A, Siskind D.
INTRODUCTION: There is increasing evidence of excess mortality in schizophrenia but less information on other non-affective psychoses. We therefore generated standardised mortality ratios (SMRs) for community-dwelling people with schizophrenia and other no... (Source: SafetyLit)
Source: SafetyLit - May 7, 2018 Category: International Medicine & Public Health Tags: Research Methods, Surveillance and Codes, Models Source Type: news

Janssen to Present Data in Treatment-Resistant Depression, Schizophrenia, Health Economics and Outcomes and Population Health at American Psychiatric Association 2018 Meeting
(Source: Johnson and Johnson)
Source: Johnson and Johnson - May 3, 2018 Category: Pharmaceuticals Source Type: news

Even brief maternal deprivation early in life alters adult brain function and cognition
(Indiana University-Purdue University Indianapolis School of Science) When a baby is taken from its mother for even a brief period early in life, this traumatic event significantly alters the future, adult function of the brain, according to a new animal model study from the School of Science at IUPUI. These changes in the brain are similar to disturbances in brain structure and function that are found in people at risk for neuropsychiatric disorders, such as schizophrenia. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - May 3, 2018 Category: International Medicine & Public Health Source Type: news

Interconnected cells-in-a-dish let researchers study brain disease
(Salk Institute) Using multiple types of cells found in the brain's hippocampus, Salk researchers modeled how connections between cells go awry in schizophrenia. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - May 3, 2018 Category: International Medicine & Public Health Source Type: news

Lab-Generated'Minibrains' Shed New Light on Schizophrenia Lab-Generated'Minibrains' Shed New Light on Schizophrenia
Cerebral organoids that model schizophrenia may lead to a better understanding of the disease processes in the human brain, as well as new targets for drug development.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 2, 2018 Category: Consumer Health News Tags: Psychiatry News Source Type: news

Nonadherence may not increase schizophrenia costs
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - May 1, 2018 Category: Drugs & Pharmacology Source Type: news

Suicidal ideation and behavior in US veterans with schizophrenia or bipolar disorder - Harvey PD, Posner K, Rajeevan N, Yershova KV, Aslan M, Concato J.
OBJECTIVE: Using data from a Department of Veterans Affairs study of schizophrenia (SZ) and bipolar I disorder (BP), we evaluated lifetime risks for suicidal ideation and behavior. We were interested in the prevalence and correlates of these outcomes, in p... (Source: SafetyLit)
Source: SafetyLit - April 30, 2018 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Mediation analyses of insight, quality of life, depression, and suicidality: results from the FACE-SZ Cohort - Roux P, Misdrahi D, Capdevielle D, Aouizerate B, Berna F, Brunel L, Chereau I, Dorey JM, Dubertret C, Dubreucq J, Faget-Agius C, Fonteneau S, Gabayet F, Llorca PM, Mallet J, Rey R, Richieri R, Schandrin A, Sch ürhoff F, Tessier A, Vidailhet P, Passerieux C, Urbach M.
OBJECTIVE: The relationship between greater insight and increased risk of suicide in patients with schizophrenia is debated. The purpose of this study was to assess whether quality of life (QoL) and depression mediated the association between insight and s... (Source: SafetyLit)
Source: SafetyLit - April 30, 2018 Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news

SPM in Real Life: Spring ’ 18
NEW MEMBERS: Spring ’18 Brief bios/plugs for new members (extracted from the Introduce Yourself Connect Community) Katherine Infantes-Cordova, a bilingual patient liaison passionate about improving the patient experience, is eager to take part in eliminating health inequities and empowering patients to be proactive in their health. Leah Jones has a background in consumer public relations and social media. Her company, Natiiv Facilitation, offers independent focus group moderation, event facilitation, and patient engagement projects. She advocates about fibroids and the challenges people struggling with their weight f...
Source: Society for Participatory Medicine - April 27, 2018 Category: General Medicine Authors: Danny van Leeuwen Tags: Newsletter Source Type: news

Medical News Today: What are delusions of grandeur?
A delusion of grandeur is a false belief in one ’s importance or greatness. A person may believe, for instance, that they are famous, can end world wars, or that they are immortal. Grandiose delusions are often caused by mental health conditions, such as schizophrenia, but can also result from dementia or brain damage. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 27, 2018 Category: Consumer Health News Tags: Mental Health Source Type: news

Substance Use Disorders Linked to Conversion to Schizophrenia
Cannabis, amphetamine, opioid use disorders all linked to conversion from schizotypal disorder (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - April 26, 2018 Category: Psychiatry Tags: Psychiatry, Journal, Source Type: news

Association of maternal exposure to terror attacks during pregnancy and the risk of schizophrenia in the offspring: a population-based study - Weinstein Y, Levav I, Gelkopf M, Roe D, Yoffe R, Pugachova I, Levine SZ.
This study tested the hypothesis that maternal exposure to terror attacks during pregnancy is associated with the risk of schizophrenia in the offspring. A population-based study was conducted of Israeli children born between 1975 and 1995 and that were re... (Source: SafetyLit)
Source: SafetyLit - April 26, 2018 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Substance Use Disorders Linked to Conversion to Schizophrenia
THURSDAY, April 26, 2018 -- Substance use disorders are associated with conversion from schizotypal disorder to schizophrenia, according to a study published online April 25 in JAMA Psychiatry. Carsten Hjorth øj, Ph.D., from Copenhagen University... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 26, 2018 Category: Pharmaceuticals Source Type: news

MRI of cortical folds may help predict psychosis
MRI can help predict which patients with prepsychotic symptoms will go on to...Read more on AuntMinnie.comRelated Reading: DTI-MRI poses new cause for schizophrenia fMRI shows LSD's adverse effects on the brain fMRI shows brain activity in early psychosis PET shows promise for migraines, schizophrenia MRS results could steer first-episode psychotics to more aggressive therapy (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - April 26, 2018 Category: Radiology Source Type: news

Cannabis Use Tied to Schizophrenia Conversion (CME/CE)
(MedPage Today) -- Similar links found with amphetamine and opioid abuse (Source: MedPage Today Pediatrics)
Source: MedPage Today Pediatrics - April 25, 2018 Category: Pediatrics Source Type: news

ARRS: DTI-MRI shows brain damage from cocaine use
WASHINGTON, DC - MRI scans with a diffusion-tensor imaging protocol (DTI-MRI)...Read more on AuntMinnie.comRelated Reading: DTI-MRI finds abnormal brain connections in autistic kids DTI-MRI ties lack of fitness to cognitive decline Court rules that DTI-MRI scans are not 'junk science' DTI-MRI poses new cause for schizophrenia DTI-MRI sheds light on Parkinson's disease (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - April 25, 2018 Category: Radiology Source Type: news

Does cannabis cause psychosis? Scientists discuss the risks
Scientists from Western Sydney University discuss how previous research suggests marijuana increases the risk of schizophrenia, while other studies imply the drug may benefit mental health. (Source: the Mail online | Health)
Source: the Mail online | Health - April 24, 2018 Category: Consumer Health News Source Type: news

DEBUNKED: Cannabis does NOT cause schizophrenia
(Natural News) It’s not unusual to hear those who are opposed to legalizing cannabis claim that it can cause people to develop mental illnesses like schizophrenia, but new research shows that there is very little truth behind the notion. According to King’s College London Psychology Research fellow Dr. Musa Sami, there is no direct correlation between... (Source: NaturalNews.com)
Source: NaturalNews.com - April 22, 2018 Category: Consumer Health News Source Type: news

Could antipsychotic drugs affect thyroid function?
Findings of an Italian study, presented at the Schizophrenia International Research Society 2018 biennial meeting, suggest that patients being treated with antipsychotics for mental health disorders are also more likely to have hypothyroidism or hyperthyroidism.Medscape (Source: Society for Endocrinology)
Source: Society for Endocrinology - April 20, 2018 Category: Endocrinology Source Type: news

Research reveals stronger people have healthier brains
(NICM, Western Sydney University) A study of nearly half a million people has revealed that muscular strength, measured by handgrip, is an indication of how healthy our brains are. The study, published in Schizophrenia Bulletin, also showed that maximal handgrip was strongly correlated with both visual memory and reaction time in over one thousand people with psychotic disorders such as schizophrenia. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - April 19, 2018 Category: International Medicine & Public Health Source Type: news

Early stages of schizophrenia can be treated with nutrients found in Brussels sprouts, shellfish, and oranges
(Natural News) Around two million Americans suffer from schizophrenia, and it’s a frustrating chronic mental illness that is marked with disabling symptoms like delusions and hallucinations. Unfortunately, the antipsychotic medications that are often given to address these problems come with their own set of risks. Now, scientists have discovered that certain nutrients could help to... (Source: NaturalNews.com)
Source: NaturalNews.com - April 16, 2018 Category: Consumer Health News Source Type: news

Acceptance and commitment therapy and family psycho education for clients with schizophrenia - Ema Komala EP, Anna Keliat B, Yulia Wardani I.
This study aims to determine the effectiveness of combining acceptance and commitment therapy with family psycho education on increased insight, diminished symptoms, and the client's improved ability to control violent behavior. METHOD: ... (Source: SafetyLit)
Source: SafetyLit - April 16, 2018 Category: International Medicine & Public Health Tags: Program and Other Evaluations, Effectiveness Studies Source Type: news

Early trauma, attachment experiences and comorbidities in schizophrenia - Gab ínio T, Ricci T, Kahn JP, Malaspina D, Moreira H, Veras AB.
OBJECTIVE To evaluate attachment patterns in subjects with schizophrenia and their relationships to early traumatic events, psychotic symptoms and comorbidities. METHODS Twenty patients diagnosed with schizophrenia according to criteria from the Di... (Source: SafetyLit)
Source: SafetyLit - April 16, 2018 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Cutting-edge Advances Help Mute Voices in Schizophrenia Cutting-edge Advances Help Mute Voices in Schizophrenia
Schizophrenia patients with auditory verbal hallucinations may benefit from creating an avatar to confront their tormentor or by transcranial stimulation, the results of two studies indicate.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 12, 2018 Category: Consumer Health News Tags: Psychiatry News Source Type: news

The 5 α-reductase inhibitor finasteride increases suicide-related aggressive behaviors and blocks clozapine-induced beneficial effects in an animal model of schizophrenia - Maurice-Gélinas C, Deslauriers J, Monpays C, Sarret P, Grignon S.
Death by suicide is 5 times higher among schizophrenia patients than in the general population. There is now compelling evidence suggesting that the pathophysiology of suicide in schizophrenia does not involve central serotonergic neurotransmission disturb... (Source: SafetyLit)
Source: SafetyLit - April 12, 2018 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Loneliness in Psychosis: A Meta-analytical Review Loneliness in Psychosis: A Meta-analytical Review
Is there an association between loneliness and psychotic symptoms in people with psychosis?Schizophrenia Bulletin (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 12, 2018 Category: Consumer Health News Tags: Psychiatry Journal Article Source Type: news

Sudden Death in Schizophrenia Sudden Death in Schizophrenia
Sudden unexpected death is not uncommon in schizophrenia. What are the most frequently implicated causes, and what do we know about their potential mechanisms?Current Opinion in Psychiatry (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 12, 2018 Category: Consumer Health News Tags: Psychiatry Journal Article Source Type: news

Sleep Disturbances Affect the Majority of Schizophrenia Patients Sleep Disturbances Affect the Majority of Schizophrenia Patients
Three quarters of schizophrenia patients have sleep disturbances, such as sleeping too long and having difficulty falling asleep. Treatment could yield physical and mental benefits, suggest two studies.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 9, 2018 Category: Consumer Health News Tags: Psychiatry News Source Type: news

Very High Risk of Substance Use, Mood Disorders in Schizophrenia Very High Risk of Substance Use, Mood Disorders in Schizophrenia
Schizophrenia patients face a high and persistent risk for subsequent substance use or mood disorder, which underlines the interconnectedness of mental health disorders, reveals Danish study.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 9, 2018 Category: Consumer Health News Tags: Psychiatry News Source Type: news

The Damaging Beliefs of Bipolar Disorder
When writer Elaina J. Martin was diagnosed with bipolar disorder, she felt “less than.” “I felt like other people were better than me, less damaged than I was.” In the first few years of her diagnosis, psychotherapist Colleen King, LMFT, worried she’d never be able to function at a higher level. “During those years of struggle, I saw myself deteriorate, become less capable, and felt like a failure in many ways.” Bipolar disorder is a difficult illness that can shatter one’s self-worth and sense of self. Beliefs tend to differ in different people, depending on the person&rsquo...
Source: Psych Central - April 8, 2018 Category: Psychiatry Authors: Margarita Tartakovsky, M.S. Tags: Bipolar Disorders General Self-Esteem Self-Help Stigma Bipolar Disorder Depressive Episode managing bipolar disorder Mental Health Stigma Negative Beliefs Sense Of Self Source Type: news

Suicidal risk, hopelessness and depression in patients with schizophrenia and internalized stigma - Touri ño R, Acosta FJ, Giráldez A, Álvarez J, González JM, Abelleira C, Benítez N, Baena E, Fernández JA, Rodriguez CJ.
BACKGROUND: Internalized stigma has negative consequences on subjective and objective aspects of the recovery in people diagnosed with mental disorders. Despite its relevance, it has been poorly studied in patients with schizophrenia. METHODS: A sa... (Source: SafetyLit)
Source: SafetyLit - April 7, 2018 Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news

Early Intervention Service Cuts Suicide Rate in Schizophrenia
FRIDAY, April 6, 2018 -- Early intervention (EI) services seem to improve the suicide rate for patients with first-episode schizophrenia-spectrum (FES) disorders, according to a study published online April 4 in JAMA Psychiatry. Sherry Kit Wa Chan,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 6, 2018 Category: Pharmaceuticals Source Type: news

Early Stop of Antipsychotics May Lead to Poor Outcomes in Schizophrenia Early Stop of Antipsychotics May Lead to Poor Outcomes in Schizophrenia
Discontinuing antipsychotic medication in some patients with first-episode psychosis may be harmful, a follow-up study from Hong Kong suggests.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 5, 2018 Category: Consumer Health News Tags: Medscape Today News Source Type: news

Children whose parents are cousins more likely to suffer from depression
Researchers from Queen's University Belfast claim the results may appear overly alarming. Most people have a 0.3-to-0.66 per cent risk of schizophrenia, which is raised to just 0.6-to-1.32 per cent. (Source: the Mail online | Health)
Source: the Mail online | Health - April 5, 2018 Category: Consumer Health News Source Type: news

Children whose parents are cousins are up to three times more likely to suffer from depression
Researchers from Queen's University Belfast claim the results may appear overly alarming. Most people have a 0.3-to-0.66 per cent risk of schizophrenia, which is raised to just 0.6-to-1.32 per cent. (Source: the Mail online | Health)
Source: the Mail online | Health - April 5, 2018 Category: Consumer Health News Source Type: news

Attention deficit disorders could stem from impaired brain coordination
(Case Western Reserve University) Researchers from Case Western Reserve University School of Medicine and colleagues have discovered how two brain regions work together to maintain attention, and how discordance between the regions could lead to attention deficit disorders, including schizophrenia, bipolar disorder, and major depression. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 5, 2018 Category: International Medicine & Public Health Source Type: news

Early Intervention Cut Suicide Risk in Schizophrenia (CME/CE)
(MedPage Today) -- Pioneering Hong Kong program succeeded, study finds (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - April 4, 2018 Category: Primary Care Source Type: news

Butterflies of the soul
(Harvard Medical School) A new study reveals how interneurons, dubbed 'the butterflies of the soul,' emerge and diversify in the brain. The findings may help inform the development of new classes of drugs for diseases such as autism, schizophrenia and Alzheimer's. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - March 30, 2018 Category: Biology Source Type: news

Accidental deaths among persons with schizophrenia: a nationwide population-based cohort study - Hellemose LAA, Laursen TM, Larsen JT, Toender A.
OBJECTIVES: Persons with schizophrenia have a shorter life expectancy by 15-20years compared to the background population, but little is known about deaths caused by accidents. We aimed to investigate the rates of accidental death among persons with schizo... (Source: SafetyLit)
Source: SafetyLit - March 29, 2018 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Lowering Antipsychotic Dose Can Improve Symptoms in Schizophrenia Lowering Antipsychotic Dose Can Improve Symptoms in Schizophrenia
Reducing the dose of risperidone and olanzapine can improve cognitive function and negative symptoms in patients with stable schizophrenia, new research from China suggests.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 27, 2018 Category: Consumer Health News Tags: Psychiatry News Source Type: news

No evidence that regularly smoking cannabis may lead to schizophrenia
Dr Musa Sami is a researcher and academic psychiatrist at King's College London. Since the 1960s, cannabis potency and rates of use have risen in many Western countries, he says. (Source: the Mail online | Health)
Source: the Mail online | Health - March 27, 2018 Category: Consumer Health News Source Type: news