Psychosis May Accelerate Brain Aging Psychosis May Accelerate Brain Aging
Accelerated aging of cognitive networks after psychosis onset may offer the potential for early intervention in patients with schizophrenia or bipolar disorder, new research suggests.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 21, 2019 Category: Consumer Health News Tags: Psychiatry News Source Type: news

Researchers create organoid of a brain region to study cognitive disorders
Yale researchers have created model thalamuses to study diseases like epilepsy, autism spectrum disorder, schizophrenia and depression. (Source: Yale Science and Health News)
Source: Yale Science and Health News - February 21, 2019 Category: Universities & Medical Training Source Type: news

Metacognitive Training and Delusional Symptoms in Psychosis Metacognitive Training and Delusional Symptoms in Psychosis
This study demonstrated the efficacy of individualized metacognitive training, a novel psychotherapy designed to specifically target delusional beliefs in people with psychosis.Schizophrenia Bulletin (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 21, 2019 Category: Consumer Health News Tags: Psychiatry Journal Article Source Type: news

Science News ┬╗ Neuromelanin-Sensitive MRI Identified as a Potential Biomarker for Psychosis
Researchers have shown that a type of magnetic resonance imaging — called neuromelanin-sensitive MRI (NM-MRI) — is a potential biomarker for psychosis. NM-MRI signal was found to be a marker of dopamine function in people with schizophrenia and an indicator of the severity of psychotic symptoms in people with this mental illness. (Source: National Institute of Mental Health)
Source: National Institute of Mental Health - February 20, 2019 Category: Psychiatry Authors: Claire Cole Source Type: news

For patients with schizophrenia, some drug combinations may be more effective than others
(Columbia University Irving Medical Center) Patients with schizophrenia are often treated with more than one type of psychiatric medication, but a new study suggests that some combinations may be more effective than others. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 20, 2019 Category: International Medicine & Public Health Source Type: news

Potential link between vitamin D deficiency and loss of brain plasticity
(University of Queensland) University of Queensland research may explain why vitamin D is vital for brain health, and how deficiency leads to disorders including depression and schizophrenia.Associate Professor Thomas Burne at UQ's Queensland Brain Institute led the studies, which provide the groundwork for research into better prevention and treatments.'Over a billion people worldwide are affected by vitamin D deficiency, and there is a well-established link between vitamin D deficiency and impaired cognition,' Dr. Burne said. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - February 19, 2019 Category: International Medicine & Public Health Source Type: news

No additional weight-loss reported from a lifestyle programme for people with psychosis
People with schizophrenia are twice as likely to be overweight as the general population, as medication side effects frequently include weight gain. This NIHR-funded study with over 400 participants in 10 areas across England is the largest UK randomised trial to date. It shows that this hard-to-reach group can be recruited and retained in structured self-management programmes delivered by trained facilitators. However, it was neither clinically effective nor cost-effective. Alternative, affordable approaches are much needed. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - February 18, 2019 Category: Consumer Health News Source Type: news

National study comparing the characteristics of patients diagnosed with schizophrenia who committed homicide vs. those who died by suicide - Baird A, Shaw J, Hunt IM, Kapur N, Appleby L, Webb RT.
Associations between serious mental disorder and violence are well-documented, but there is little epidemiological evidence linking these disorders and homicide risk. The reported study compares socio-demographic and clinical characteristics of people diag... (Source: SafetyLit)
Source: SafetyLit - February 18, 2019 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Neuromelanin-sensitive MRI identified as a potential biomarker for psychosis
(NIH/National Institute of Mental Health) Researchers have shown that a type of magnetic resonance imaging -- called neuromelanin-sensitive MRI (NM-MRI) -- is a potential biomarker for psychosis. NM-MRI signal was found to be a marker of dopamine function in people with schizophrenia and an indicator of the severity of psychotic symptoms in people with this mental illness. The study was funded, in part, by the National Institute of Mental Health (NIMH), part of the National Institutes of Health. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 18, 2019 Category: International Medicine & Public Health Source Type: news

How Common is Bipolar Disorder?
Discussion Bipolar disorder (BD) is a chronic, recurrent, affective disorder with fluctuations in energy and mood. “Bipolar disorder, previously known as manic depressive illness, is a severe chronic mood disorder characterized by episodes [note not just one instance] of mania, hypomania, and alternating or intertwining episodes of depression.” Affective disorders are classified based on their severity and extent, from unipolar to BDII to BDI. “Individuals with unipolar disorder present with depressive episodes only, and those with bipolar II or I disorder show increasingly pronounced episodes of mood ele...
Source: PediatricEducation.org - February 18, 2019 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

What Psychotic Episodes Really Look and Feel Like
When we hear someone is psychotic, we automatically think of psychopaths and cold-blooded criminals. We automatically think “Oh wow, they’re really crazy!” And we automatically think of plenty of other myths and misconceptions that only further the stigma surrounding psychosis. In other words, the reality is that we get psychosis very wrong. For starters, psychosis consists of hallucinations and/or delusions. “You can have one or both at the same time,” said Devon MacDermott, Ph.D, a psychologist who previously worked in psychiatric hospitals and outpatient centers, treating individuals experi...
Source: Psych Central - February 17, 2019 Category: Psychiatry Authors: Margarita Tartakovsky, M.S. Tags: Disorders General Schizophrenia Stigma Hallucinations Hearing Voices Psychosis Psychotic Episode serious mental illness Source Type: news

New drug raises hopes of reversing memory loss in old age
Toronto researchers believe the drug can also help those with depression, schizophrenia and Alzheimer ’sAn experimental drug that bolsters ailing brain cells has raised hopes of a treatment for memory loss, poor decision making and other mental impairments that often strike in old age.The drug could be taken as a daily pill by over-55s if clinical trials, which are expected to start within two years, show that the medicine is safe and effective at preventing memory lapses.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - February 14, 2019 Category: Science Authors: Ian Sample Science editor Tags: Neuroscience Memory Medical research Mental health Drugs World news Alzheimer's Society Ageing Schizophrenia Depression Canada Americas Source Type: news

Wisdom Linked to Cognitive Performance in Schizophrenia
THURSDAY, Feb. 14, 2019 -- For people with schizophrenia (PwS), wisdom is associated with better cognitive performance, according to a study published online Feb. 14 in Schizophrenia Research. Ryan Van Patten, Ph.D., from the University of... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 14, 2019 Category: Pharmaceuticals Source Type: news

The ways of wisdom in schizophrenia
(University of California - San Diego) Researchers at UC San Diego School of Medicine report that persons with schizophrenia scored lower on a wisdom assessment than non-psychiatric comparison participants, but that there was considerable variability in levels of wisdom, and those with higher scores displayed fewer psychotic symptoms. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - February 14, 2019 Category: International Medicine & Public Health Source Type: news

Medical News Today: Bipolar and schizophrenia symptoms
Bipolar disorder and schizophrenia have some similarities, but there are key differences. Diagnosis and treatment options vary. Here, learn more about the two conditions and when to see a doctor. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 14, 2019 Category: Consumer Health News Tags: Bipolar Source Type: news

Minocycline Reduce Synaptic Pruning in Schizophrenia Cell Models Minocycline Reduce Synaptic Pruning in Schizophrenia Cell Models
Minocycline reduces excessive synaptic pruning in schizophrenia patient-derived cell models, suggesting that it might delay or prevent the onset of schizophrenia in some individuals, according to new research.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - February 13, 2019 Category: Pathology Tags: Psychiatry News Source Type: news

Dating With Schizophrenia
Dating when you have schizophrenia can be a challenge. But your condition doesn’t have to stand in the way of a happy, healthy relationship. Get tips on easing into the dating game. (Source: WebMD Health)
Source: WebMD Health - February 12, 2019 Category: Consumer Health News Source Type: news

"But what about real mental illnesses?" alternatives to the disease model approach to "schizophrenia" - Cooke A, Kinderman P.
The old dichotomy between "neurosis" and "psychosis" appears to be alive and well in the debate about psychiatric diagnosis. It is often suggested that while diagnostic alternatives may be appropriate for the relatively common forms of distress with which ... (Source: SafetyLit)
Source: SafetyLit - February 8, 2019 Category: International Medicine & Public Health Tags: Commentary Source Type: news

Push Is On to Reclassify Schizophrenia as a Neurologic Disease Push Is On to Reclassify Schizophrenia as a Neurologic Disease
Schizophrenia is classified as a psychiatric disorder. An advocacy group is seeking to reclassify it as a neurologic disease to obtain CDC funding and reduce stigma.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 7, 2019 Category: Consumer Health News Tags: Psychiatry News Source Type: news

Does a history of violence predict higher antipsychotic dosage in schizophrenia? - Colbert-Kaip S, Wang KZ, Bani-Fatemi A, Baddour J, Dada O, Alli S, Zai C, Graff A, Kolla N, De Luca V.
[Abstract unavailable] Language: en... (Source: SafetyLit)
Source: SafetyLit - February 6, 2019 Category: International Medicine & Public Health Tags: Violence and Weapons Issues Source Type: news

Eye Movements May Flag Cognitive Impairment in Schizophrenia Eye Movements May Flag Cognitive Impairment in Schizophrenia
A Japanese study found a significant association between visual exploration and scores on a cognitive test requiring visual search in patients with schizophrenia.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 4, 2019 Category: Consumer Health News Tags: Psychiatry News Source Type: news

What Schizophrenia Symptoms and Stigma Feel Like
Experts and people with schizophrenia describe what it’s like to live with this debilitating mental illness. (Source: WebMD Health)
Source: WebMD Health - February 1, 2019 Category: Consumer Health News Source Type: news

Book Review: Simply Human:  Reflections on the Life We Share
In his new book, Simply Human: Reflections on the Life We Share, Alan Bodnar takes us inside the lives of people with mental illness, providing the keen insight and discernment of a clinical psychologist to show that their stories are all part of a much larger human experience. Bodnar explains, “I wanted to convey some of the fear, confusion, and betrayal that these people were feeling, and, in some small way, give voice to the distress that policymakers seemed to be ignoring.” Here, Bodnar is referring to the stigma that so often encompasses people who have mental illness, a stigma that perpetuates society&rsq...
Source: Psych Central - February 1, 2019 Category: Psychiatry Authors: Claire Nana Tags: Book Reviews Disorders Ethics & Morality General Happiness Memory and Perception Motivation and Inspiration Personal Stories Psychology Psychotherapy Stigma Treatment Bodnar Empathy Humanity Mental Illness Prejudice Simpl Source Type: news

Early risers may have a lower risk of mental health problems
Research, published inNature Communications, suggests that individuals with genetics that predispose them to be early risers have a lower risk of schizophrenia and depression.Guardian (Source: Society for Endocrinology)
Source: Society for Endocrinology - January 31, 2019 Category: Endocrinology Source Type: news

White matter microstructure in schizophrenia patients with a history of violence - Tesli N, Westlye LT, Storvestre GB, Gurholt TP, Agartz I, Melle I, Andreassen OA, Haukvik UK.
Schizophrenia (SCZ) is associated with increased risk of violence compared to the general population. Neuroimaging research suggests SCZ to be a disorder of disrupted connectivity, with diffusion tensor imaging (DTI) indicating white matter (WM) abnormalit... (Source: SafetyLit)
Source: SafetyLit - January 31, 2019 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Medical News Today: Schizophrenia: Restoring brain circuitry to improve symptoms
Researchers finally zero in on the brain network that drives the severity of negative symptoms in schizophrenia and suggest a noninvasive treatment. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 31, 2019 Category: Consumer Health News Tags: Schizophrenia Source Type: news

Cat Poop and Schizophrenia; Cannabis for a 4-Year-Old
(MedPage Today) -- News and commentary from the psychiatry world (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - January 30, 2019 Category: Psychiatry Source Type: news

UCLA-led team uncovers critical new clues about what goes awry in brains of people with autism
This study gives a new critical clue in understanding what has gone awry in the brains of autism patients.”More than 24 million people worldwide are estimated to have autism. In developed countries, about 1.5 percent of children have been diagnosed with autism spectrum disorder as of 2017. The disorder affects communication and behavior, and is marked by problems in social communication and social interaction, and repetitive behaviors.“We need to understand how a panoply of genetic and environmental factors converges to cause autism,” Geschwind said. “RNA editing is an important piece of the autism ...
Source: UCLA Newsroom: Health Sciences - January 30, 2019 Category: Universities & Medical Training Source Type: news

Mind-altering parasite spread by CATS 'may lead to schizophrenia'
People with the infection were 50 per cent more likely to have schizophrenia, Danish researchers found. Findings add to previous research showing a link to mind-altering behaviours. (Source: the Mail online | Health)
Source: the Mail online | Health - January 30, 2019 Category: Consumer Health News Source Type: news

BIDMC researchers ID, treat faulty brain circuitry underlying symptoms of schizophrenia
(Beth Israel Deaconess Medical Center) In a first-of-its-kind study, Beth Israel Deaconess Medical Center researchers determined the underlying anatomical cause of certain symptoms of schizophrenia, then ameliorated them with non-invasive brain stimulation. The scientists reported in the American Journal of Psychiatry that these symptoms arise from a breakdown in a network between the brain's prefrontal cortex and the cerebellum, and that non-invasive brain stimulation restored network function, which in turn improved schizophrenia's most debilitating symptoms. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - January 30, 2019 Category: International Medicine & Public Health Source Type: news

Research sheds light on body clock and links to mental health and disease
A large-scale genomic analysis has revealed some of the inner workings of the body clock, suggesting that being genetically programmed to rise early may lead to greater well-being and a lower risk of schizophrenia and depression. (Source: Medical Research Council General News)
Source: Medical Research Council General News - January 29, 2019 Category: Research Source Type: news

New findings about anti-malaria drug
(University of W ü rzburg) Researchers at the Rudolf Virchow Center of the University of W ü rzburg have unveiled the molecular effectiveness of artemisinins. The findings could lead to drugs for diseases such as Alzheimer's, schizophrenia and epilepsy. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 29, 2019 Category: International Medicine & Public Health Source Type: news

Correlation between violence and antipsychotic dosage in schizophrenia: a secondary analysis of the Clinical Antipsychotic Trials for Intervention Effectiveness (CATIE) dataset - Tasmim S, Kolla NJ, Dada O, Bani-Fatemi A, De Luca V.
INTRODUCTION: Violent behavior is more common in individuals with schizophrenia, compared to the general population. Studies suggest higher psychotic symptoms are predictive of greater violent behavior. On the other hand, violent behaviors are reduced with... (Source: SafetyLit)
Source: SafetyLit - January 24, 2019 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Copy number variants contribute to risk of 'schizophrenia-like' bipolar disorder subtype
(Elsevier) A form of rare genomic structural variation called copy number variants (CNVs) may be more closely associated with schizophrenia than bipolar disorder. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - January 24, 2019 Category: International Medicine & Public Health Source Type: news

The role of illness engulfment in the association between insight and depressive symptomatology in schizophrenia - Konsztowicz S, Lepage M.
Good clinical insight in schizophrenia tends to be associated with better outcomes, but also with increased depression. We hypothesized that illness engulfment, a process whereby an individual's self-concept becomes defined solely by illness and the 'patie... (Source: SafetyLit)
Source: SafetyLit - January 22, 2019 Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news

The role of substance use and adult sexual assault severity in the course of schizophrenia: an epidemiological catchment study of sexual assault victims - Rabinovitz S, Goldman K, Rosca P, Barda J, Levine SZ.
This study aims to examine the associations between substance use and sexual assault severity characteristics ... (Source: SafetyLit)
Source: SafetyLit - January 22, 2019 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Inability to integrate reward info contributes to undervalued rewards in schizophrenia
(Elsevier) People with schizophrenia have a hard time integrating information about a reward -- the size of the reward and the probability of receiving it -- when assessing its value, according to a study in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - January 22, 2019 Category: International Medicine & Public Health Source Type: news

Metacognition and Performance-Based Empathy in Schizophrenia Metacognition and Performance-Based Empathy in Schizophrenia
People with schizophrenia experience significant deficits in empathic skills. What is the relationship of metacognitive capacity and personal distress with empathic performance in schizophrenia?Schizophrenia Bulletin (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 21, 2019 Category: Consumer Health News Tags: Psychiatry Journal Article Source Type: news

Schizophrenia: Genetic Mutation Alters Teen Brain, Raises Risk Schizophrenia: Genetic Mutation Alters Teen Brain, Raises Risk
Schizophrenia may be caused by a genetic mutation in the SLC39A8 gene that leads to a structural abnormality in the brain during adolescence, suggesting a new target for therapy.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 18, 2019 Category: Consumer Health News Tags: Psychiatry News Source Type: news

Does Marijuana Use Cause Schizophrenia?
As the drug becomes more popular, concerns have been raised that its use can lead to psychotic disorders. Here ’ s what scientists know for sure, and what they don ’ t. (Source: NYT Health)
Source: NYT Health - January 18, 2019 Category: Consumer Health News Authors: BENEDICT CAREY Tags: Marijuana Drug Abuse and Traffic Schizophrenia Mental Health and Disorders Genetics and Heredity Research Brain Smoking and Tobacco Source Type: news

Does Cannabis Use Cause Schizophrenia?
As the drug becomes more popular, concerns have been raised that its use can lead to psychotic disorders. Here ’ s what scientists know for sure, and what they don ’ t. (Source: NYT Health)
Source: NYT Health - January 17, 2019 Category: Consumer Health News Authors: BENEDICT CAREY Tags: Marijuana Drug Abuse and Traffic Schizophrenia Mental Health and Disorders Genetics and Heredity Research Brain Smoking and Tobacco Source Type: news

Cerebellar modulation of the reward circuitry and social behavior
The cerebellum has been implicated in a number of nonmotor mental disorders such as autism spectrum disorder, schizophrenia, and addiction. However, its contribution to these disorders is not well understood. In mice, we found that the cerebellum sends direct excitatory projections to the ventral tegmental area (VTA), one of the brain regions that processes and encodes reward. Optogenetic activation of the cerebello-VTA projections was rewarding and, in a three-chamber social task, these projections were more active when the animal explored the social chamber. Intriguingly, activity in the cerebello-VTA pathway was require...
Source: ScienceNOW - January 17, 2019 Category: Science Authors: Carta, I., Chen, C. H., Schott, A. L., Dorizan, S., Khodakhah, K. Tags: Neuroscience, Online Only r-articles Source Type: news

Schizophrenia may be linked to a genetic mutation in childhood
Schizophrenia may come from a structural abnormality caused by a genetic mutation in the brain during childhood, a study says. (Source: Health News - UPI.com)
Source: Health News - UPI.com - January 16, 2019 Category: Consumer Health News Source Type: news

Cholesterol, Diabetes, BP Meds May Help Serious Mental Illness Cholesterol, Diabetes, BP Meds May Help Serious Mental Illness
Drug-repurposing research suggests a role for statins, calcium channel blockers, and metformin in treating schizophrenia and other serious mental illness.Medscape Medical News (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - January 16, 2019 Category: Endocrinology Tags: Psychiatry News Source Type: news

Schizophrenia linked to genetic structural abnormality in adolescent brain
(University of Warwick) Schizophrenia could be caused by a genetic mutation that causes a structural abnormality in the brain during adolescence. Therefore testing for the gene SLC39A8, and brain scans for schizophrenia could predict whether or not someone will develop it -- researchers at the University of Warwick have found. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - January 16, 2019 Category: International Medicine & Public Health Source Type: news

Advances in the study of drugs to combat cognitive impairment in schizophrenia
(University of the Basque Country) A study by the UPV/EHU has assessed the effectiveness of various drugs, which are used to delay cognitive deterioration in patients with Alzheimer's, in improving cognitive impairment displayed by patients with schizophrenia. Through an analysis of nine clinical trials carried out worldwide, the researchers have specified a series of methodological improvements in the study of drugs that ensure the functional recovery of these patients. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 15, 2019 Category: International Medicine & Public Health Source Type: news

Does glandular fever lead to schizophrenia? Study reveals a link
Schizophrenia patients were more than twice likely to have virus antibodies, researchers at Johns Hopkins Medicine and Sheppard Pratt Health System, Baltimore, found. (Source: the Mail online | Health)
Source: the Mail online | Health - January 14, 2019 Category: Consumer Health News Source Type: news

Medical News Today: Have researchers found a new risk factor for schizophrenia?
New research draws a link between infection with the Epstein-Barr virus and schizophrenia, though cause and effect relationships remain unclear. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 14, 2019 Category: Consumer Health News Tags: Schizophrenia Source Type: news

B-group vitamins can improve concentration among people with first episode psychosis
(Orygen, the National Centre of Excellence in Youth Mental Health) The study, led by Dr Colin O'Donnell, now at Letterkenny University Hospital, and Dr Kelly Allott from Orygen, explored the impact of increasing a person's intake of vitamins B12, B6, and folic acid [vitamin B9] after studies in people with schizophrenia revealed that increased intake of these vitamins could decrease patients' levels of an amino acid called homocysteine and improve their symptoms. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - January 14, 2019 Category: International Medicine & Public Health Source Type: news

Common Heart, Diabetes Meds May Help Ease Mental Illness
THURSDAY, Jan. 10, 2019 -- A new study is raising the question of whether certain cholesterol, blood pressure and diabetes drugs could help manage mental illnesses like schizophrenia. The findings come from a study of over 142,000 Swedish patients... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - January 10, 2019 Category: General Medicine Source Type: news