Endoplasmic Reticulum Stress Induces Macrophages to Produce IL-1 β During Mycobacterium bovis Infection via a Positive Feedback Loop Between Mitochondrial Damage and Inflammasome Activation
Yi Liao, Tariq Hussain, Chunfa Liu, Yongyong Cui, Jie Wang, Jiao Yao, Hehua Chen, Yinjuan Song, Naveed Sabir, Mazhar Hussain, Deming Zhao, Xiangmei Zhou (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 21, 2019 Category: Allergy & Immunology Source Type: research

Effect of in vivo Hydroxychloroquine and ex vivo Anti-BDCA2 mAb Treatment on pDC IFN α Production From Patients Affected With Cutaneous Lupus Erythematosus
Agnes Gardet, Alex Pellerin, Christie-Ann McCarl, Rohan Diwanji, Wenting Wang, Douglas Donaldson, Nathalie Franchimont, Victoria P. Werth, Dania Rabah (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 21, 2019 Category: Allergy & Immunology Source Type: research

Maternal Immune Response During Pregnancy and Vertical Transmission in Human Toxoplasmosis
Fernando G ómez-Chávez, Irma Cañedo-Solares, Luz Belinda Ortiz-Alegría, Yevel Flores-García, Héctor Luna-Pastén, Ricardo Figueroa-Damián, Juan Carlos Mora-González, Dolores Correa (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 21, 2019 Category: Allergy & Immunology Source Type: research

Single Cell Based Phosphorylation Profiling Identifies Alterations in Toll-Like Receptor 7 and 9 Signaling in Patients With Primary Sj ögren's Syndrome
Richard Davies, Irene Sarkar, Daniel Hammenfors, Brith Bergum, Petra Vogelsang, Silje M. Solberg, Sonia Gavasso, Johan G. Brun, Roland Jonsson, Silke Appel (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 21, 2019 Category: Allergy & Immunology Source Type: research

Crucial Role of Nucleic Acid Sensing via Endosomal Toll-Like Receptors for the Defense of Streptococcus pyogenes in vitro and in vivo
Anna Hafner, Ulrike Kolbe, Isabel Freund, Virginia Castiglia, Pavel Kovarik, Tanja Poth, Franziska Herster, Markus A. Weigand, Alexander N. R. Weber, Alexander H. Dalpke, Tatjana Eigenbrod (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 21, 2019 Category: Allergy & Immunology Source Type: research

CXCL13 as a Biomarker of Immune Activation During Early and Chronic HIV Infection
Vikram Mehraj, Rayoun Ramendra, St éphane Isnard, Franck P. Dupuy, Bertrand Lebouché, Cecilia Costiniuk, Réjean Thomas, Jason Szabo, Jean-Guy Baril, Benoit Trottier, Pierre Coté, Roger LeBlanc, Madéleine Durand, Carl Chartrand-Lefebvre, Ido Kema, Yonglong Zhang, Malcolm Finkelman, Cécile Tremblay, Jean-Pierre Routy (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 21, 2019 Category: Allergy & Immunology Source Type: research

Generation and Immune Regulation of CD4+CD25 −Foxp3+ T Cells in Chronic Obstructive Pulmonary Disease
Jiang-Hua Wu, Mei Zhou, Yang Jin, Zhao-Ji Meng, Xian-Zhi Xiong, Sheng-Wen Sun, Shuai-Ying Miao, Hong-Li Han, Xiao-Nan Tao (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 20, 2019 Category: Allergy & Immunology Source Type: research

Galectin-9 Mediates HIV Transcription by Inducing TCR-Dependent ERK Signaling
Florent Colomb, Leila B. Giron, Thomas A. Premeaux, Brooks I. Mitchell, Toshiro Niki, Emmanouil Papasavvas, Luis J. Montaner, Lishomwa C. Ndhlovu, Mohamed Abdel-Mohsen (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 20, 2019 Category: Allergy & Immunology Source Type: research

Commentary: Gut microbiome –mediated bile acid metabolism regulates liver cancer via NKT cells
Baolei Jia (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 20, 2019 Category: Allergy & Immunology Source Type: research

Mechanisms of Action of Hematopoietic Transcription Factor PU.1 in Initiation of T-Cell Development
Ellen V. Rothenberg, Hiroyuki Hosokawa, Jonas Ungerb äck (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 20, 2019 Category: Allergy & Immunology Source Type: research

Fueling Cancer Immunotherapy With Common Gamma Chain Cytokines
Connor J. Dwyer, Hannah M. Knochelmann, Aubrey S. Smith, Megan M. Wyatt, Guillermo O. Rangel Rivera, Dimitrios C. Arhontoulis, Eric Bartee, Zihai Li, Mark P. Rubinstein, Chrystal M. Paulos (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 20, 2019 Category: Allergy & Immunology Source Type: research

Prime-Boost Vaccine Regimen for SjTPI and SjC23 Schistosome Vaccines, Increases Efficacy in Water Buffalo in a Field Trial in China
Akram A. Da'Dara, Changlin Li, Xinling Yu, Mao Zheng, Jie Zhou, Lisa M. Shollenberger, Yue-sheng Li, Donald A. Harn (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 20, 2019 Category: Allergy & Immunology Source Type: research

Potential Therapeutic Features of Human Amniotic Mesenchymal Stem Cells in Multiple Sclerosis: Immunomodulation, Inflammation Suppression, Angiogenesis Promotion, Oxidative Stress Inhibition, Neurogenesis Induction, MMPs Regulation, and Remyelination Stimulation
Mohsen Abbasi-Kangevari, Seyyed-Hadi Ghamari, Fahimeh Safaeinejad, Soheyl Bahrami, Hassan Niknejad (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 20, 2019 Category: Allergy & Immunology Source Type: research

Revisiting the Tissue Microenvironment of Infectious Mononucleosis: Identification of EBV Infection in T Cells and Deep Characterization of Immune Profiles
M ário Henrique M. Barros, Gabriela Vera-Lozada, Priscilla Segges, Rocio Hassan, Gerald Niedobitek (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 20, 2019 Category: Allergy & Immunology Source Type: research

Aberrant Expressions of Co-stimulatory and Co-inhibitory Molecules in Autoimmune Diseases
Weiwei He, Bin Wang, Qian Li, Qiuming Yao, Xi Jia, Ronghua Song, Sheli Li, Jin-an Zhang (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 20, 2019 Category: Allergy & Immunology Source Type: research

LL37 Inhibits Aspergillus fumigatus Infection via Directly Binding to the Fungus and Preventing Excessive Inflammation
Xiao-Li Luo, Jian-Xiong Li, Hua-Rong Huang, Jie-Lin Duan, Ruo-Xuan Dai, Ru-Jia Tao, Ling Yang, Jia-yun Hou, Xin-Ming Jia, Jin-Fu Xu (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 20, 2019 Category: Allergy & Immunology Source Type: research

Reprogrammed CD4+ T Cells That Express FoxP3+ Control Inhibitory Antibody Formation in Hemophilia A Mice
Roland W. Herzog, Veronica Kuteyeva, Rania Saboungi, Cox Terhorst, Moanaro Biswas (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 20, 2019 Category: Allergy & Immunology Source Type: research

Thioredoxin Modulates Protein Arginine Deiminase 4 (PAD4)-Catalyzed Citrullination
Mitesh Nagar, Ronak Tilvawala, Paul R. Thompson (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 19, 2019 Category: Allergy & Immunology Source Type: research

Beta2-Integrins and Interacting Proteins in Leukocyte Trafficking, Immune Suppression, and Immunodeficiency Disease
Susanna C. Fagerholm, Carla Guenther, Marc Llort Asens, Terhi Savinko, Liisa M. Uotila (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 19, 2019 Category: Allergy & Immunology Source Type: research

Role of NFAT5 in the Immune System and Pathogenesis of Autoimmune Diseases
Naeun Lee, Donghyun Kim, Wan-Uk Kim (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 19, 2019 Category: Allergy & Immunology Source Type: research

Human Immune Responses and the Natural History of Neisseria gonorrhoeae Infection
Angela Lovett, Joseph A. Duncan (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 19, 2019 Category: Allergy & Immunology Source Type: research

Host Transcriptomics as a Tool to Identify Diagnostic and Mechanistic Immune Signatures of Tuberculosis
Julie G. Burel, Mariana Babor, Mikhail Pomaznoy, Cecilia S. Lindestam Arlehamn, Nabeela Khan, Alessandro Sette, Bjoern Peters (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 19, 2019 Category: Allergy & Immunology Source Type: research

Microbiome and Autoimmune Uveitis
Reiko Horai, Rachel R. Caspi (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 19, 2019 Category: Allergy & Immunology Source Type: research

Reverse Signaling of Tumor Necrosis Factor Superfamily Proteins in Macrophages and Microglia: Superfamily Portrait in the Neuroimmune Interface
Won-Ha Lee, Donggun Seo, Su-Geun Lim, Kyoungho Suk (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 19, 2019 Category: Allergy & Immunology Source Type: research

Two to Tango: Co-evolution of Hominid Natural Killer Cell Receptors and MHC
Emily E. Wroblewski, Peter Parham, Lisbeth A. Guethlein (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 19, 2019 Category: Allergy & Immunology Source Type: research

Humanized Mouse Models of Rheumatoid Arthritis for Studies on Immunopathogenesis and Preclinical Testing of Cell-Based Therapies
Katina Schinnerling, Carlos Rosas, Lilian Soto, Ranjeny Thomas, Juan Carlos Aguill ón (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 19, 2019 Category: Allergy & Immunology Source Type: research

Proteasome Dependent Actin Remodeling Facilitates Antigen Extraction at the Immune Synapse of B Cells
Jorge Iba ñez-Vega, Felipe Del Valle Batalla, Juan José Saez, Andrea Soza, Maria-Isabel Yuseff (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 19, 2019 Category: Allergy & Immunology Source Type: research

BCG Vaccination Induces M. avium and M. abscessus Cross-Protective Immunity
Getahun Abate, Fahreta Hamzabegovic, Christopher S. Eickhoff, Daniel F. Hoft (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 19, 2019 Category: Allergy & Immunology Source Type: research

Transcriptome Profiles of Human Visceral Adipocytes in Obesity and Colorectal Cancer Unravel the Effects of Body Mass Index and Polyunsaturated Fatty Acids on Genes and Biological Processes Related to Tumorigenesis
Manuela Del Corn ò, Antonella Baldassarre, Enrica Calura, Lucia Conti, Paolo Martini, Chiara Romualdi, Rosaria Varì, Beatrice Scazzocchio, Massimo D'Archivio, Andrea Masotti, Sandra Gessani (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 19, 2019 Category: Allergy & Immunology Source Type: research

Diet in the Driving Seat: Natural Diet-Immunity-Microbiome Interactions in Wild Fish
Ida M. Friberg, Joe D. Taylor, Joseph A. Jackson (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 19, 2019 Category: Allergy & Immunology Source Type: research

Paralogs of Common Carp Granulocyte Colony-Stimulating Factor (G-CSF) Have Different Functions Regarding Development, Trafficking and Activation of Neutrophils
Fumihiko Katakura, Kohei Nishiya, Annelieke S. Wentzel, Erika Hino, Jiro Miyamae, Masaharu Okano, Geert F. Wiegertjes, Tadaaki Moritomo (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 19, 2019 Category: Allergy & Immunology Source Type: research

Model-Based Assessment of the Role of Uneven Partitioning of Molecular Content on Heterogeneity and Regulation of Differentiation in CD8 T-Cell Immune Responses
Simon Girel, Christophe Arpin, Jacqueline Marvel, Olivier Gandrillon, Fabien Crauste (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 19, 2019 Category: Allergy & Immunology Source Type: research

Utility of Hybrid Transferrin Binding Protein Antigens for Protection Against Pathogenic Neisseria Species
Jamie E. Fegan, Charles Calmettes, Epshita A. Islam, Sang Kyun Ahn, Somshukla Chaudhuri, Rong-hua Yu, Scott D. Gray-Owen, Trevor F. Moraes, Anthony B. Schryvers (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 19, 2019 Category: Allergy & Immunology Source Type: research

Genome-Wide CRISPR Screening Identifies JAK1 Deficiency as a Mechanism of T-Cell Resistance
Ping Han, Qiang Dai, Lilv Fan, Hao Lin, Xiaoqing Zhang, Fanlin Li, Xuanming Yang (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 19, 2019 Category: Allergy & Immunology Source Type: research

Circulating Mucosal-Associated Invariant T Cells in a Large Cohort of Healthy Chinese Individuals From Newborn to Elderly
Pengcheng Chen, Wenhai Deng, Dandan Li, Tai Zeng, Ling Huang, Qun Wang, Jinli Wang, Weiguang Zhang, Xiaoxiao Yu, Deming Duan, Jinle Wang, Hong Xia, Hanbin Chen, Wesley Huang, Jingao Li, Dahong Zhang, Xiao-Ping Zhong, Jimin Gao (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 19, 2019 Category: Allergy & Immunology Source Type: research

Requirement for Cyclic AMP/Protein Kinase A-Dependent Canonical NF κB Signaling in the Adjuvant Action of Cholera Toxin and Its Non-toxic Derivative mmCT
Manuela Terrinoni, Jan Holmgren, Michael Lebens, Maximilian Larena (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 19, 2019 Category: Allergy & Immunology Source Type: research

Infection-Induced Resistance to Experimental Cerebral Malaria Is Dependent Upon Secreted Antibody-Mediated Inhibition of Pathogenic CD8+ T Cell Responses
Tovah N. Shaw, Colette A. Inkson, Ana Villegas-Mendez, David J. Pattinson, Patrick Strangward, Kathryn J. Else, Simon J. Draper, Leo A. H. Zeef, Kevin N. Couper (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 19, 2019 Category: Allergy & Immunology Source Type: research

The Regulatory T Cell in Active Systemic Lupus Erythematosus Patients: A Systemic Review and Meta-Analysis
Wenli Li, Chuiwen Deng, Hanbo Yang, Guochun Wang (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 18, 2019 Category: Allergy & Immunology Source Type: research

Elevated Soluble PD-L1 in Pregnant Women's Serum Suppresses the Immune Reaction
Mai Okuyama, Hidetoshi Mezawa, Toshinao Kawai, Mitsuyoshi Urashima (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 18, 2019 Category: Allergy & Immunology Source Type: research

Comparative Extracellular Proteomics of Aeromonas hydrophila Reveals Iron-Regulated Secreted Proteins as Potential Vaccine Candidates
Yuqian Wang, Xiaoyun Wang, Farman Ali, Zeqi Li, Yuying Fu, Xiaojun Yang, Wenxiong Lin, Xiangmin Lin (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 18, 2019 Category: Allergy & Immunology Source Type: research

Human Mast Cells From Adipose Tissue Target and Induce Apoptosis of Breast Cancer Cells
Jesse D. Plotkin, Michael G. Elias, Mohammad Fereydouni, Tracy R. Daniels-Wells, Anthony L. Dellinger, Manuel L. Penichet, Christopher L. Kepley (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 18, 2019 Category: Allergy & Immunology Source Type: research

Pro-inflammatory Cytokines Alter the Immunopeptidome Landscape by Modulation of HLA-B Expression
Aaron Javitt, Eilon Barnea, Matthias P. Kramer, Hila Wolf-Levy, Yishai Levin, Arie Admon, Yifat Merbl (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 18, 2019 Category: Allergy & Immunology Source Type: research

The Impact of Immune Interventions: A Systems Biology Strategy for Predicting Adverse and Beneficial Immune Effects
Marjolein Meijerink, Tim van den Broek, Remon Dulos, Lotte Neergaard Jacobsen, Anne Staudt Kvistgaard, Jossie Garthoff, L éon Knippels, Karen Knipping, Geert Houben, Lars Verschuren, Jolanda van Bilsen (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 15, 2019 Category: Allergy & Immunology Source Type: research

Alarmins of the S100-Family in Juvenile Autoimmune and Auto-Inflammatory Diseases
Dirk Holzinger, Klaus Tenbrock, Johannes Roth (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 15, 2019 Category: Allergy & Immunology Source Type: research

Genetic Modification Strategies to Enhance CAR T Cell Persistence for Patients With Solid Tumors
Christopher DeRenzo, Stephen Gottschalk (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 15, 2019 Category: Allergy & Immunology Source Type: research

Molecular Basis of the Differentiation and Function of Virus Specific Follicular Helper CD4+ T Cells
Qizhao Huang, Jianjun Hu, Jianfang Tang, Lifan Xu, Lilin Ye (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 15, 2019 Category: Allergy & Immunology Source Type: research

Gut Microbiome as Target for Innovative Strategies Against Food Allergy
Roberto Berni Canani, Lorella Paparo, Rita Nocerino, Carmen Di Scala, Giusy Della Gatta, Ylenia Maddalena, Aniello Buono, Cristina Bruno, Luana Voto, Danilo Ercolini (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 15, 2019 Category: Allergy & Immunology Source Type: research

T-Cell-Driven Inflammation as a Mediator of the Gut-Brain Axis Involved in Parkinson's Disease
Javier Campos-Acu ña, Daniela Elgueta, Rodrigo Pacheco (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 15, 2019 Category: Allergy & Immunology Source Type: research

Role of Radiation Therapy in Modulation of the Tumor Stroma and Microenvironment
Hari Menon, Rishab Ramapriyan, Taylor R. Cushman, Vivek Verma, Hans H. Kim, Jonathan E. Schoenhals, Cemre Atalar, Ugur Selek, Stephen G. Chun, Joe Y. Chang, Hampartsoum B. Barsoumian, Quynh-Nhu Nguyen, Mehmet Altan, Maria A. Cortez, Stephen M. Hahn, James W. Welsh (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 15, 2019 Category: Allergy & Immunology Source Type: research

Thrombin Contributes to Anti-myeloperoxidase Antibody Positive IgG-Mediated Glomerular Endothelial Cells Activation Through SphK1-S1P-S1PR3 Signaling
Xiao-Jing Sun, Min Chen, Ming-Hui Zhao (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 15, 2019 Category: Allergy & Immunology Source Type: research