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Therapeutic Potential of Gene-Modified Regulatory T Cells: From Bench to Bedside
Wook-Jin Chae, Alfred L. M. Bothwell (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 16, 2018 Category: Allergy & Immunology Source Type: research

Features of Effective T Cell-Inducing Vaccines against Chronic Viral Infections
Eleni Panagioti, Paul Klenerman, Lian N. Lee, Sjoerd H. van der Burg, Ramon Arens (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 16, 2018 Category: Allergy & Immunology Source Type: research

Autoantibodies in Autoimmune Hepatitis: Can Epitopes Tell Us about the Etiology of the Disease?
Urs Christen, Edith Hintermann (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 16, 2018 Category: Allergy & Immunology Source Type: research

Antigen Loading (e.g., Glutamic Acid Decarboxylase 65) of Tolerogenic DCs (tolDCs) Reduces Their Capacity to Prevent Diabetes in the Non-Obese Diabetes (NOD)-Severe Combined Immunodeficiency Model of Adoptive Cotransfer of Diabetes As Well As in NOD Mice
David P. Funda, Jaroslav Goli áš, Tomáš Hudcovic, Hana Kozáková, Radek Špíšek, Lenka Palová-Jelínková (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 16, 2018 Category: Allergy & Immunology Source Type: research

Dried Blood Spots, an Affordable Tool to Collect, Ship, and Sequence gDNA from Patients with an X-Linked Agammaglobulinemia Phenotype Residing in a Developing Country
Gesmar R. S. Segundo, Anh T. V. Nguyen, Huyen T. Thuc, Le N. Q. Nguyen, Roger H. Kobayashi, Hai T. Le, Huong T. M. Le, Troy R. Torgerson, Hans D. Ochs (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 16, 2018 Category: Allergy & Immunology Source Type: research

The Host Restriction Factor Interferon-Inducible Transmembrane Protein 3 Inhibits Vaccinia Virus Infection
Chang Li, Shouwen Du, Mingyao Tian, Yuhang Wang, Jieying Bai, Peng Tan, Wei Liu, Ronglan Yin, Maopeng Wang, Ying Jiang, Yi Li, Na Zhu, Yilong Zhu, Tiyuan Li, Shipin Wu, Ningyi Jin, Fuchu He (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 16, 2018 Category: Allergy & Immunology Source Type: research

Clinical, Immunological, and Molecular Findings in Five Patients with Major Histocompatibility Complex Class II Deficiency from India
Jahnavi Aluri, Maya Gupta, Aparna Dalvi, Snehal Mhatre, Manasi Kulkarni, Gouri Hule, Mukesh Desai, Nitin Shah, Prasad Taur, Ramprasad Vedam, Manisha Madkaikar (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 16, 2018 Category: Allergy & Immunology Source Type: research

Pentose Phosphate Shunt Modulates Reactive Oxygen Species and Nitric Oxide Production Controlling Trypanosoma cruzi in Macrophages
Sue-jie Koo, Bartosz Szczesny, Xianxiu Wan, Nagireddy Putluri, Nisha Jain Garg (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 16, 2018 Category: Allergy & Immunology Source Type: research

The Rac Activator DOCK2 Mediates Plasma Cell Differentiation and IgG Antibody Production
Miho Ushijima, Takehito Uruno, Akihiko Nishikimi, Fumiyuki Sanematsu, Yasuhisa Kamikaseda, Kazufumi Kunimura, Daiji Sakata, Takaharu Okada, Yoshinori Fukui (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 16, 2018 Category: Allergy & Immunology Source Type: research

Whole-Genome Expression Profiling in Skin Reveals SYK As a Key Regulator of Inflammation in Experimental Epidermolysis Bullosa Acquisita
Unni K. Samavedam, Nina Mitschker, Anika Kasprick, Katja Bieber, Enno Schmidt, Tam ás Laskay, Andreas Recke, S. Goletz, Gestur Vidarsson, Franziska S. Schulze, Mikko Armbrust, Katharina Schulze Dieckhoff, Hendri H. Pas, Marcel F. Jonkman, Kathrin Kalies, Detlef Zillikens, Yask Gupta, Saleh M. Ibrahim, Ralf J. Ludwig (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 15, 2018 Category: Allergy & Immunology Source Type: research

C-Type Lectin-Like Receptors As Emerging Orchestrators of Sterile Inflammation Represent Potential Therapeutic Targets
Elise Chiffoleau (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 15, 2018 Category: Allergy & Immunology Source Type: research

African Trypanosomiasis-Associated Anemia: The Contribution of the Interplay between Parasites and the Mononuclear Phagocyte System
Benoit Stijlemans, Patrick De Baetselier, Stefan Magez, Jo A. Van Ginderachter, Carl De Trez (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 15, 2018 Category: Allergy & Immunology Source Type: research

Chimeric Antigen Receptor Expressing Natural Killer Cells for the Immunotherapy of Cancer
Rohtesh S. Mehta, Katayoun Rezvani (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 15, 2018 Category: Allergy & Immunology Source Type: research

Engineered T Regulatory Type 1 Cells for Clinical Application
Silvia Gregori, Maria Grazia Roncarolo (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 15, 2018 Category: Allergy & Immunology Source Type: research

Infection Elicited Autoimmunity and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: An Explanatory Model
Jonas Blomberg, Carl-Gerhard Gottfries, Amal Elfaitouri, Muhammad Rizwan, Anders Ros én (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 15, 2018 Category: Allergy & Immunology Source Type: research

Dexamethasone-Induced Myeloid-Derived Suppressor Cells Prolong Allo Cardiac Graft Survival through iNOS- and Glucocorticoid Receptor-Dependent Mechanism
Yang Zhao, Xiao-Fei Shen, Ke Cao, Jie Ding, Xing Kang, Wen-xian Guan, Yi-tao Ding, Bao-rui Liu, Jun-Feng Du (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 15, 2018 Category: Allergy & Immunology Source Type: research

Proximity of Cytomegalovirus-Specific CD8+ T Cells to Replicative Senescence in Human Immunodeficiency Virus-Infected Individuals
John Joseph Heath, Neva Jennifer Fudge, Maureen Elizabeth Gallant, Michael David Grant (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 15, 2018 Category: Allergy & Immunology Source Type: research

Interleukin (IL)-6 Inhibits IL-27- and IL-30-Mediated Inflammatory Responses in Human Monocytes
Carlene Petes, M élissa K. Mariani, Yawen Yang, Nathalie Grandvaux, Katrina Gee (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 15, 2018 Category: Allergy & Immunology Source Type: research

Histopathological Correlations between Mediastinal Fat-Associated Lymphoid Clusters and the Development of Lung Inflammation and Fibrosis following Bleomycin Administration in Mice
Yaser Hosny Ali Elewa, Osamu Ichii, Kensuke Takada, Teppei Nakamura, Md. Abdul Masum, Yasuhiro Kon (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 15, 2018 Category: Allergy & Immunology Source Type: research

Acquired Natural Killer Cell Dysfunction in the Tumor Microenvironment of Classic Hodgkin Lymphoma
Jodi Chiu, Daniel M. Ernst, Armand Keating (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 14, 2018 Category: Allergy & Immunology Source Type: research

Preterm Life in Sterile Conditions: A Study on Preterm, Germ-Free Piglets
Alla Splichalova, Vera Slavikova, Zdislava Splichalova, Igor Splichal (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 14, 2018 Category: Allergy & Immunology Source Type: research

Altered Toll-Like Receptor-4 Response to Lipopolysaccharides in Infants Exposed to HIV-1 and Its Preventive Therapy
Anicet Christel Maloupazoa Siawaya, Ofilia Mvoundza Ndjindji, Eliane Kuissi Kamgaing, Amandine Mveang-Nzoghe, Ch érone Nancy Mbani Mpega, Marielle Leboueny, Roselyne Kengue Boussougou, Armel Mintsa Ndong, Paulin N. Essone, Joel Fleury Djoba Siawaya (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 14, 2018 Category: Allergy & Immunology Source Type: research

Serum Levels of Migration Inhibitory Factor (MIF) and In Situ Expression of MIF and Its Receptor CD74 in Lepromatous Leprosy Patients: A Preliminary Report
Marco Alonso Martinez-Guzman, Anabell Alvarado-Navarro, Vidal Delgado-Rizo, Alejandra Garcia-Orozco, Jorge Arturo Mayorga-Rodr íguez, Ana Laura Pereira-Suarez, Mary Fafutis-Morris (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 14, 2018 Category: Allergy & Immunology Source Type: research

Phosphatidylserine-Liposomes Promote Tolerogenic Features on Dendritic Cells in Human Type 1 Diabetes by Apoptotic Mimicry
Silvia Rodriguez-Fernandez, Irma Pujol-Autonell, Ferran Brianso, David Perna-Barrull, Mary Cano-Sarabia, Sonia Garcia-Jimeno, Adrian Villalba, Alex Sanchez, Eva Aguilera, Federico Vazquez, Joan Verdaguer, Daniel Maspoch, Marta Vives-Pi (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 14, 2018 Category: Allergy & Immunology Source Type: research

From CD4-Based Initiation to Treating All HIV-Infected Adults Immediately: An Evidence-Based Meta-analysis
Aixin Song, Xinchao Liu, Xiaojie Huang, Kathrine Meyers, Djin-Ye Oh, Jianhua Hou, Wei Xia, Bin Su, Ni Wang, Xiaofan Lu, Huan Xia, Xiaodong Yang, Hui Chen, Hao Wu (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 13, 2018 Category: Allergy & Immunology Source Type: research

Dectin-1-Syk-CARD9 Signaling Pathway in TB Immunity
Matthew Wagener, J. Claire Hoving, Hlumani Ndlovu, Mohlopheni J. Marakalala (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 13, 2018 Category: Allergy & Immunology Source Type: research

The Aryl Hydrocarbon Receptor and Tumor Immunity
Ping Xue, Jinrong Fu, Yufeng Zhou (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 13, 2018 Category: Allergy & Immunology Source Type: research

Clinical Grade Regulatory CD4+ T Cells (Tregs): Moving Toward Cellular-Based Immunomodulatory Therapies
Richard Duggleby, Robert David Danby, J. Alejandro Madrigal, Aurore Saudemont (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 13, 2018 Category: Allergy & Immunology Source Type: research

Allergen and Epitope Targets of Mouse-Specific T Cell Responses in Allergy and Asthma
V éronique Schulten, Luise Westernberg, Giovanni Birrueta, John Sidney, Sinu Paul, Paula Busse, Bjoern Peters, Alessandro Sette (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 13, 2018 Category: Allergy & Immunology Source Type: research

Macrophages in the Human Cochlea: Saviors or Predators —A Study Using Super-Resolution Immunohistochemistry
Wei Liu, Matyas Molnar, Carolyn Garnham, Heval Benav, Helge Rask-Andersen (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 13, 2018 Category: Allergy & Immunology Source Type: research

Loss of Rictor in Monocyte/Macrophages Suppresses Their Proliferation and Viability Reducing Atherosclerosis in LDLR Null Mice
Vladimir R. Babaev, Jiansheng Huang, Lei Ding, Youmin Zhang, James M. May, MacRae F. Linton (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 13, 2018 Category: Allergy & Immunology Source Type: research

Beta-Defensin 2 and 3 Promote Bacterial Clearance of Pseudomonas aeruginosa by Inhibiting Macrophage Autophagy through Downregulation of Early Growth Response Gene-1 and c-FOS
Yongjian Wu, Dandan Li, Yi Wang, Xi Liu, Yuanqing Zhang, Wenting Qu, Kang Chen, Ngiambudulu M. Francisco, Lianqiang Feng, Xi Huang, Minhao Wu (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 13, 2018 Category: Allergy & Immunology Source Type: research

Respiratory Influenza A Virus Infection Triggers Local and Systemic Natural Killer Cell Activation via Toll-Like Receptor 7
Sabine Stegemann-Koniszewski, Sarah Behrens, Julia D. Boehme, Inga Hochnadel, Peggy Riese, Carlos A. Guzm án, Andrea Kröger, Jens Schreiber, Matthias Gunzer, Dunja Bruder (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 13, 2018 Category: Allergy & Immunology Source Type: research

C-Type Lectin Receptor (CLR) –Fc Fusion Proteins As Tools to Screen for Novel CLR/Bacteria Interactions: An Exemplary Study on Preselected Campylobacter jejuni Isolates
Sabine Mayer, Rebecca Moeller, Jo ão T. Monteiro, Kerstin Ellrott, Christine Josenhans, Bernd Lepenies (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 13, 2018 Category: Allergy & Immunology Source Type: research

Molecular Basis for the Recognition of Herpes Simplex Virus Type 1 Infection by Human Natural Killer Cells
Hong-Sheng Dai, Michael A. Caligiuri (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 12, 2018 Category: Allergy & Immunology Source Type: research

Human γ-Herpesvirus Infection, Tumorigenesis, and Immune Control in Mice with Reconstituted Human Immune System Components
Christian M ünz (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 12, 2018 Category: Allergy & Immunology Source Type: research

Twenty Years of AIRE
Roberto Perniola (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 12, 2018 Category: Allergy & Immunology Source Type: research

More than Decoration: Roles for Natural Killer Group 2 Member D Ligand Expression by Immune Cells
Andrew P. Trembath, Mary A. Markiewicz (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 12, 2018 Category: Allergy & Immunology Source Type: research

A New Classification System for IgG4 Autoantibodies
Inga Koneczny (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 12, 2018 Category: Allergy & Immunology Source Type: research

Cow ’s Milk and Immune Function in the Respiratory Tract: Potential Mechanisms
Olaf Perdijk, Marloes van Splunter, Huub F. J. Savelkoul, Sylvia Brugman, R. J. Joost van Neerven (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 12, 2018 Category: Allergy & Immunology Source Type: research

The Possible Effect of B-Cell Epitopes of Epstein –Barr Virus Early Antigen, Membrane Antigen, Latent Membrane Protein-1, and -2A on Systemic Lupus Erythematosus
Jianxin Tu, Xiaobing Wang, Guannan Geng, Xiangyang Xue, Xiangyang Lin, Xiaochun Zhu, Li Sun (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 12, 2018 Category: Allergy & Immunology Source Type: research

Hepatitis B Virus-Specific CD8+ T Cells Maintain Functional Exhaustion after Antigen Reexposure in an Acute Activation Immune Environment
Qin Wang, Wen Pan, Yanan Liu, Jinzhuo Luo, Dan Zhu, Yinping Lu, Xuemei Feng, Xuecheng Yang, Ulf Dittmer, Mengji Lu, Dongliang Yang, Jia Liu (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 12, 2018 Category: Allergy & Immunology Source Type: research

Unique Immune Gene Expression Patterns in Bronchoalveolar Lavage and Tumor Adjacent Non-Neoplastic Lung Tissue in Non-Small Cell Lung Cancer
Chih-Hsi Scott Kuo, Chien-Ying Liu, Stelios Pavlidis, Yu-Lun Lo, Yen-Wen Wang, Chih-Hung Chen, How-Wen Ko, Fu-Tsai Chung, Tin-Yu Lin, Tsai-Yu Wang, Kang-Yun Lee, Yi-Ke Guo, Tzu-Hao Wang, Cheng-Ta Yang (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 12, 2018 Category: Allergy & Immunology Source Type: research

Human Properdin Opsonizes Nanoparticles and Triggers a Potent Pro-inflammatory Response by Macrophages without Involving Complement Activation
Lubna Kouser, Basudev Paudyal, Anuvinder Kaur, Gudrun Stenbeck, Lucy A. Jones, Suhair M. Abozaid, Cordula M. Stover, Emmanuel Flahaut, Robert B. Sim, Uday Kishore (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 12, 2018 Category: Allergy & Immunology Source Type: research

V γ4 T Cells Inhibit the Pro-healing Functions of Dendritic Epidermal T Cells to Delay Skin Wound Closure Through IL-17A
Yashu Li, Yangping Wang, Lina Zhou, Meixi Liu, Guangping Liang, Rongshuai Yan, Yufeng Jiang, Jianlei Hao, Xiaorong Zhang, Xiaohong Hu, Yong Huang, Rupeng Wang, Zhinan Yin, Jun Wu, Gaoxing Luo, Weifeng He (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 12, 2018 Category: Allergy & Immunology Source Type: research

Pathogenicity and Viral Shedding of MERS-CoV in Immunocompromised Rhesus Macaques
Joseph Prescott, Darryl Falzarano, Emmie de Wit, Kath Hardcastle, Friederike Feldmann, Elaine Haddock, Dana Scott, Heinz Feldmann, Vincent Jacobus Munster (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 12, 2018 Category: Allergy & Immunology Source Type: research

Prolactin and Autoimmunity
V ânia Vieira Borba, Gisele Zandman-Goddard, Yehuda Shoenfeld (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 12, 2018 Category: Allergy & Immunology Source Type: research

Abnormal Epigenetic Regulation of Immune System during Aging
Miriam G. Jasiulionis (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 12, 2018 Category: Allergy & Immunology Source Type: research

Exosomes in Pathogen Infections: A Bridge to Deliver Molecules and Link Functions
Wenchao Zhang, Xiaofeng Jiang, Jinghui Bao, Yi Wang, Huixing Liu, Lijun Tang (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 12, 2018 Category: Allergy & Immunology Source Type: research

Agonistic Autoantibodies to the β2-Adrenergic Receptor Involved in the Pathogenesis of Open-Angle Glaucoma
Anselm J ünemann, Bettina Hohberger, Jürgen Rech, Ahmed Sheriff, Qin Fu, Ursula Schlötzer-Schrehardt, Reinhard Edmund Voll, Sabine Bartel, Hubert Kalbacher, Johan Hoebeke, Robert Rejdak, Folkert Horn, Gerd Wallukat, Rudolf Kunze, Martin Herrmann (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 12, 2018 Category: Allergy & Immunology Source Type: research