Enhancing sweet potato (Ipomoea batatas) resilience grown in cadmium-contaminated saline soil: a synergistic approach using Moringa leaf extract and effective microorganisms application
Environ Sci Pollut Res Int. 2024 Apr 23. doi: 10.1007/s11356-024-33295-w. Online ahead of print.ABSTRACTRaising soil contamination with cadmium (Cd2+) and salinization necessitates the development of green approaches using bio-elicitors to ensure sustainable crop production and mitigate the detrimental health impacts. Two field trials were carried out to study the individual and combined effects of foliage spraying of Moringa leaf extract (MLE) and soil application of effective microorganisms (EMs) on the physio-biochemical, osmolytes, antioxidants, and performance of sweet potato grown in Cd2+-contaminated salty soil (Cd2...
Source: Environmental Science and Pollution Research International - April 23, 2024 Category: Environmental Health Authors: Abdelsattar Abdelkhalik Nasr M Abdou Mohammad A H Gyushi Ahmed Shaaban Shimaa A Abd El-Mageed Khaulood A Hemida Taia A Abd El-Mageed Source Type: research
Temperature influence on the sensitivity of Artemia franciscana to globally used pesticides - Oxyfluorfen and copper
Chemosphere. 2024 Apr 21;357:142092. doi: 10.1016/j.chemosphere.2024.142092. Online ahead of print.ABSTRACTClimate change further the world's human population increase is a mainstream political issue, and it's critical to search for solutions to produce enough food to feed everyone. Pesticides and fertilizers have been used as an easy solution to prevent pests and increase food production. Nevertheless, their overuse has dangerous effects on the ecosystems and communities. Oxyfluorfen (Oxy) and copper (Cu) based formulations are used as pesticides and widely applied on agricultural fields for crop protection. However, they...
Source: Chemosphere - April 23, 2024 Category: Chemistry Authors: A F Mesquita F J M Gon çalves A M M Gon çalves Source Type: research
Mechano-sensor Piezo1 inhibits glucagon production in pancreatic α-cells
CONCLUSION: Our study uncovers the regulatory role of the Piezo1 ion channel in α cells. Piezo1 influences glucagon production by affecting mTOR signaling pathway.PMID:38653360 | DOI:10.1016/j.bbadis.2024.167185 (Source: Biochimica et Biophysica Acta)
Source: Biochimica et Biophysica Acta - April 23, 2024 Category: Biochemistry Authors: Wenying Guo Luyang Gao Haocong Mo Handan Deng Yawen Zhao Geyang Xu Source Type: research
GSE264347 Emergence of metabolic coupling to the heterotroph Alteromonas promotes dark survival in Prochlorococcus
Contributors : Allison Coe ; Rogier Braakman ; Steven J Biller ; Aldo Arellano ; Christina Bliem ; Nhi N Vo ; Konnor von Emster ; Elaina Thomas ; Michelle DeMers ; Claudia Steglich ; Jef Huisman ; Sallie W ChisholmSeries Type : Expression profiling by high throughput sequencingOrganism : Alteromonas macleodii ; Prochlorococcus marinus str. NATL2AProchlorococcus is found throughout the euphotic zone in the oligotrophic open ocean. Deep mixing and sinking in aggregates or while attached to particles can, however, transport cells below this sunlit zone, depriving them of light for extended periods of time and influen...
Source: GEO: Gene Expression Omnibus - April 23, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Alteromonas macleodii Prochlorococcus marinus str. NATL2A Source Type: research
IJERPH, Vol. 21, Pages 517: The Association between Body Mass Index and Glycohemoglobin (HbA1c) in the US Population & rsquo;s Diabetes Status
IJERPH, Vol. 21, Pages 517: The Association between Body Mass Index and Glycohemoglobin (HbA1c) in the US Population’s Diabetes Status
International Journal of Environmental Research and Public Health doi: 10.3390/ijerph21050517
Authors:
Wenxue Lin
Obesity, indicated by Body Mass Index (BMI), is a risk factor for type 2 diabetes. However, its association with glycated hemoglobin (HbA1c), a crucial indicator of blood-sugar control, may vary across different populations and disease statuses. Data from the National Health and Nutrition Examination Survey (NHANES) 2017–2018 were analyzed. Partic...
Source: International Journal of Environmental Research and Public Health - April 23, 2024 Category: Environmental Health Authors: Wenxue Lin Tags: Article Source Type: research
The potential molecular mechanism underlying gypenoside amelioration of atherosclerosis in ApoE(-/-) mice: A multi-omics investigation
In conclusion, Gyp appeared to have complex effects on atherosclerosis, most of which were positive. These results support the use of Gyp in the treatment of atherosclerosis.PMID:38644881 | PMC:PMC11031777 | DOI:10.1016/j.heliyon.2024.e29164 (Source: Atherosclerosis)
Source: Atherosclerosis - April 22, 2024 Category: Cardiology Authors: Xing Ju Yufeng Liu Ying Wang Guoyuan Sui Yixin Ma Huimin Cao Yuan Cao Jin Wu Ying Du Xue Leng Lianqun Jia Guanlin Yang Source Type: research
Detection of Sulfoquinovosidase Activity in Cell Lysates Using Activity-Based Probes
Angew Chem Int Ed Engl. 2024 Apr 22:e202401358. doi: 10.1002/anie.202401358. Online ahead of print.ABSTRACTThe sulfolipid sulfoquinovosyl diacylglycerol (SQDG), produced by plants, algae, and cyanobacteria, constitutes a major sulfur reserve in the biosphere. Microbial breakdown of SQDG is critical for the biological utilization of its sulfur. This commences through release of the parent sugar, sulfoquinovose (SQ), catalyzed by sulfoquinovosidases (SQases). These vanguard enzymes are encoded in gene clusters that code for diverse SQ catabolic pathways. To identify, visualize and isolate glycoside hydrolase CAZY-family 31 (...
Source: Angewandte Chemie - April 22, 2024 Category: Chemistry Authors: Zirui Li Isabelle Pickles Mahima Sharma Benjamin Melling Jeroen Codee Luise Pallasdies Spencer Williams Herman Overkleeft Gideon John Davies Source Type: research
Liver glycogen fragility in the presence of hydrogen-bond breakers
Int J Biol Macromol. 2024 Apr 20;268(Pt 1):131741. doi: 10.1016/j.ijbiomac.2024.131741. Online ahead of print.ABSTRACTGlycogen, a complex branched glucose polymer, is responsible for sugar storage in blood glucose homeostasis. It comprises small β particles bound together into composite α particles. In diabetic livers, α particles are fragile, breaking apart into smaller particles in dimethyl sulfoxide, DMSO; they are however stable in glycogen from healthy animals. We postulate that the bond between β particles in α particles involves hydrogen bonding. Liver-glycogen fragility in normal and db/db mice (an animal mode...
Source: International Journal of Biological Macromolecules - April 22, 2024 Category: Biochemistry Authors: Xinle Tan Ziyi Wang Ut Cheung Zhenxia Hu Qinghua Liu Liang Wang Mitchell A Sullivan Daniel Cozzolino Robert G Gilbert Source Type: research
Healthcare processes for parent participation in neonatal intensive care units: A self-determination theory perspective
. (Source: Health Marketing Quarterly)
Source: Health Marketing Quarterly - April 22, 2024 Category: International Medicine & Public Health Authors: Steven W. RayburnSidney AndersonYamile C. Jacksona Marketing, Texas State University, San Marcos, TX, USAb CEO, Nurtured by Design, Sugar Land, TX, USA Source Type: research
Molecules, Vol. 29, Pages 1904: Molecular Dynamics Simulation of Kir6.2 Variants Reveals Potential Association with Diabetes Mellitus
In this study, we examined the effect of mutations on the Kir6.2 structure using bioinformatics tools and molecular dynamic simulations (SIFT, PolyPhen, SNAP2, PANTHER, PhD&SNP, SNP&Go, I-Mutant, MuPro, MutPred, ConSurf, HOPE, and GROMACS). Our results indicated that M199R, R201H, R206H, and Y330H mutations influence Kir6.2 structure and function and therefore may cause DM. We conclude that MD simulations are useful techniques to predict the effects of mutations on protein structure. In addition, the M199R, R201H, R206H, and Y330H variant in the Kir6.2 protein may be associated with DM. These result...
Source: Molecules - April 22, 2024 Category: Chemistry Authors: Mohamed E. Elangeeb Imadeldin Elfaki Ali M. S. Eleragi Elsadig Mohamed Ahmed Rashid Mir Salem M. Alzahrani Ruqaiah I. Bedaiwi Zeyad M. Alharbi Mohammad Muzaffar Mir Mohammad Rehan Ajmal Faris Jamal Tayeb Jameel Barnawi Tags: Article Source Type: research
Atractylodin ameliorates lipopolysaccharide-induced depressive-like behaviors in mice through reducing neuroinflammation and neuronal damage
In this study, the lipopolysaccharide (LPS)-induced mouse model was used to explore the antidepressant effects and molecular mechanisms of atractylodin. The results showed that atractylodin increased sugar preference, also reduced immobility time in FST and TST. (Source: Journal of Neuroimmunology)
Source: Journal of Neuroimmunology - April 22, 2024 Category: Allergy & Immunology Authors: Feng Liu, Yaping Wang, Dongbo Li, Tao Yang Source Type: research
Effect of nanoformulation Azadirachta indica on some factors associated with the vectorial capacity and competence of Anopheles aquasalis experimentally infected with Plasmodium vivax
In conclusion, these findings suggest that the A. indica nanoformulation is a potential as a tool for malaria control through reduction in the vector longevity and reproductive capacity, possibly leading to decreased vector population densities. Moreover, the nanoformulation interfered with the sporogonic development of P. vivax. However, further basic research on Neem formulations, their effects, and mechanisms of action is imperative to gain a more specific perspective for safe field implementation.PMID:38642694 | DOI:10.1016/j.actatropica.2024.107223 (Source: Acta Tropica)
Source: Acta Tropica - April 20, 2024 Category: Infectious Diseases Authors: Paula Andrea Urrea Aguirre Keillen Monick Martins Campos Duv án Dueñas López Fernando Orozco S ánchez Alberto Tob ón Castaño Claudia Mar ía Ríos Velásquez Adriana Pab ón Vidal Source Type: research
Evaluation of prediabetes patients in terms of metabolic syndrome
CONCLUSIONS: Hypertension, dyslipidemia, abdominal obesity, and metabolic obesity increased in the coexistence of prediabetes and MetS. At the same time, the coexistence of prediabetes and MetS was associated with higher systolic blood pressure, postprandial blood sugar, and LDL levels. Prediabetic individuals accompanied by MetS are at greater metabolic risk.PMID:38639515 | DOI:10.26355/eurrev_202404_35904 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - April 19, 2024 Category: Drugs & Pharmacology Authors: S Genc B Evren M N Ayd ın I Sahin Source Type: research
Activation of glycosyl methylpropiolates by TfOH
Carbohydr Res. 2024 Apr 9;539:109106. doi: 10.1016/j.carres.2024.109106. Online ahead of print.ABSTRACTActivation of glycosyl methylpropiolates by TfOH was investigated. Armed and superarmed glycosyl donors can be activated by use of 0.2 equivalent TfOH whereas 1.0 equivalent of TfOH was required for the activation of the disarmed glycosyl donors. All the glycosidations gave very good yields. The method is suitable for synthesis of glycosides and disaccharides and it may result in the hydrolysis of the interglycosidic bond if the sugar at the non-reducing end is armed or superarmed. These problems are not seen when gold-ca...
Source: Carbohydrate Research - April 19, 2024 Category: Genetics & Stem Cells Authors: Gulab Walke Niteshlal Kasdekar Soumyaranjan Pati Marc Taillefer Florian Jaroschik Srinivas Hotha Source Type: research
Evaluation of prediabetes patients in terms of metabolic syndrome
CONCLUSIONS: Hypertension, dyslipidemia, abdominal obesity, and metabolic obesity increased in the coexistence of prediabetes and MetS. At the same time, the coexistence of prediabetes and MetS was associated with higher systolic blood pressure, postprandial blood sugar, and LDL levels. Prediabetic individuals accompanied by MetS are at greater metabolic risk.PMID:38639515 | DOI:10.26355/eurrev_202404_35904 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 19, 2024 Category: Drugs & Pharmacology Authors: S Genc B Evren M N Ayd ın I Sahin Source Type: research
