Kids SIPsmartER reduces sugar-sweetened beverages among Appalachian middle-school students and their caregivers: a cluster randomized controlled trial
CONCLUSIONS: Kids SIPsmartER was effective at reducing SSB consumption among students and their caregivers in the rural, medically underserved Appalachian region. Importantly, SSB effects were even stronger among students and caregivers who were high consumers at baseline.TRIAL REGISTRATION: Clincialtrials.gov: NCT03740113. Registered 14 November 2018- Retrospectively registered, https://clinicaltrials.gov/ct2/show/NCT03740113 .PMID:38664715 | DOI:10.1186/s12966-024-01594-7 (Source: Health Physics)
Source: Health Physics - April 25, 2024 Category: Physics Authors: Jamie M Zoellner Wen You Kathleen Porter Brittany Kirkpatrick Annie Reid Donna Brock Phillip Chow Lee Ritterband Source Type: research
Molecular simulation on the interaction between trehalose and asymmetric lipid bilayer mimicking the membrane of human red blood cells
In this study, we conducted atomistic molecular dynamic simulations on asymmetric model bilayers that mimic the membrane of human red blood cells at various trehalose and water contents. We considered three different hydration levels mimicking the full hydration to desiccation scenarios. Results indicate that the asymmetric distribution of lipids did not significantly influence the computed structural characteristics at full and low hydration. At dehydration, however, the order parameter obtained from the symmetric bilayer is significantly higher compared to those obtained from asymmetric ones. Analysis of hydrogen bonds r...
Source: Cryobiology - April 25, 2024 Category: Biology Authors: Yu Cao Cai Gao Lei Yang Pei Zhou Dongfang Sun Source Type: research
The antiglycation potential of H1 receptor antagonists - in vitro studies in bovine serum albumin model and in silico molecular docking analyses
Biomed Pharmacother. 2024 Apr 24;175:116632. doi: 10.1016/j.biopha.2024.116632. Online ahead of print.ABSTRACTThe H1 receptor belongs to the family of rhodopsin-like G-protein-coupled receptors activated by the biogenic amine histamine. H1 receptor antagonists are widely used in the treatment of allergies. However, these drugs could have a much broader spectrum of activity, including hypoglycemic effects, which can broaden the spectrum of their use. The aim of the study was to evaluate the antiglycation potential of twelve H1 receptor antagonists (diphenhydramine, antazoline, promethazine, ketotifen, clemastine, pheniramin...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - April 25, 2024 Category: Drugs & Pharmacology Authors: Grzegorz Biedrzycki Blanka Wolszczak-Biedrzycka Justyna Dorf Daniel Michalak Ma łgorzata Żendzian-Piotrowska Anna Zalewska Mateusz Maciejczyk Source Type: research
The effects of Atractylodes macrocephala extract BZEP self-microemulsion based on gut-liver axis HDL/LPS signaling pathway to ameliorate metabolic dysfunction-associated fatty liver disease in rats
CONCLUSION: BZEPWR and BZEP exert restorative and reversal effects on the pathophysiological damage to the gut-liver axis in MAFLD rats, and the therapeutic mechanism may be related to the regulation of the intestinal flora and the HDL/LPS signaling pathway.PMID:38663104 | DOI:10.1016/j.biopha.2024.116519 (Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie)
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - April 25, 2024 Category: Drugs & Pharmacology Authors: Bo Li Xiao-Feng Jiang Ying-Jie Dong Yi-Piao Zhang Xing-Li-Shang He Cheng-Liang Zhou Yan-Yan Ding Ning Wang Yi-Bin Wang Wan-Qi Cheng Ning-Hua Jiang Jie Su Gui-Yuan Lv Su-Hong Chen Source Type: research
Kids SIPsmartER reduces sugar-sweetened beverages among Appalachian middle-school students and their caregivers: a cluster randomized controlled trial
CONCLUSIONS: Kids SIPsmartER was effective at reducing SSB consumption among students and their caregivers in the rural, medically underserved Appalachian region. Importantly, SSB effects were even stronger among students and caregivers who were high consumers at baseline.TRIAL REGISTRATION: Clincialtrials.gov: NCT03740113. Registered 14 November 2018- Retrospectively registered, https://clinicaltrials.gov/ct2/show/NCT03740113 .PMID:38664715 | DOI:10.1186/s12966-024-01594-7 (Source: Cancer Control)
Source: Cancer Control - April 25, 2024 Category: Cancer & Oncology Authors: Jamie M Zoellner Wen You Kathleen Porter Brittany Kirkpatrick Annie Reid Donna Brock Phillip Chow Lee Ritterband Source Type: research
Higher Sugar Intake Associated with Higher Risk of Depression
According to this study.PMID:38661707 | DOI:10.1097/01.NAJ.0001016400.61479.0c (Source: The American Journal of Nursing)
Source: The American Journal of Nursing - April 25, 2024 Category: Nursing Authors: Karen Rosenberg Source Type: research
Structural effects of oxidation on sugars: glucose as a precursor of gluconolactone and glucuronolactone
We present an experimental work on the changes in the structure and interactions of two products of glucose oxidation (D-glucono-1,5-lactone (GlcL) and D-glucurono-6,3-lactone (GlcurL)) with respect to their precursor. Features such as intramolecular interactions, ring puckering and tautomerism were observed.PMID:38661549 | DOI:10.1039/d4cc00735b (Source: Chemical Communications)
Source: Chemical Communications - April 25, 2024 Category: Chemistry Authors: Maider Parra-Santamaria Aran Insausti Elena R Alonso Francisco J Basterretxea Emilio J Cocinero Source Type: research
Kids SIPsmartER reduces sugar-sweetened beverages among Appalachian middle-school students and their caregivers: a cluster randomized controlled trial
CONCLUSIONS: Kids SIPsmartER was effective at reducing SSB consumption among students and their caregivers in the rural, medically underserved Appalachian region. Importantly, SSB effects were even stronger among students and caregivers who were high consumers at baseline.TRIAL REGISTRATION: Clincialtrials.gov: NCT03740113. Registered 14 November 2018- Retrospectively registered, https://clinicaltrials.gov/ct2/show/NCT03740113 .PMID:38664715 | PMC:PMC11046896 | DOI:10.1186/s12966-024-01594-7 (Source: Health Physics)
Source: Health Physics - April 25, 2024 Category: Physics Authors: Jamie M Zoellner Wen You Kathleen Porter Brittany Kirkpatrick Annie Reid Donna Brock Phillip Chow Lee Ritterband Source Type: research
Molecular simulation on the interaction between trehalose and asymmetric lipid bilayer mimicking the membrane of human red blood cells
In this study, we conducted atomistic molecular dynamic simulations on asymmetric model bilayers that mimic the membrane of human red blood cells at various trehalose and water contents. We considered three different hydration levels mimicking the full hydration to desiccation scenarios. Results indicate that the asymmetric distribution of lipids did not significantly influence the computed structural characteristics at full and low hydration. At dehydration, however, the order parameter obtained from the symmetric bilayer is significantly higher compared to those obtained from asymmetric ones. Analysis of hydrogen bonds r...
Source: Cryobiology - April 25, 2024 Category: Biology Authors: Yu Cao Cai Gao Lei Yang Pei Zhou Dongfang Sun Source Type: research
The antiglycation potential of H1 receptor antagonists - in vitro studies in bovine serum albumin model and in silico molecular docking analyses
Biomed Pharmacother. 2024 Apr 24;175:116632. doi: 10.1016/j.biopha.2024.116632. Online ahead of print.ABSTRACTThe H1 receptor belongs to the family of rhodopsin-like G-protein-coupled receptors activated by the biogenic amine histamine. H1 receptor antagonists are widely used in the treatment of allergies. However, these drugs could have a much broader spectrum of activity, including hypoglycemic effects, which can broaden the spectrum of their use. The aim of the study was to evaluate the antiglycation potential of twelve H1 receptor antagonists (diphenhydramine, antazoline, promethazine, ketotifen, clemastine, pheniramin...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - April 25, 2024 Category: Drugs & Pharmacology Authors: Grzegorz Biedrzycki Blanka Wolszczak-Biedrzycka Justyna Dorf Daniel Michalak Ma łgorzata Żendzian-Piotrowska Anna Zalewska Mateusz Maciejczyk Source Type: research
The effects of Atractylodes macrocephala extract BZEP self-microemulsion based on gut-liver axis HDL/LPS signaling pathway to ameliorate metabolic dysfunction-associated fatty liver disease in rats
CONCLUSION: BZEPWR and BZEP exert restorative and reversal effects on the pathophysiological damage to the gut-liver axis in MAFLD rats, and the therapeutic mechanism may be related to the regulation of the intestinal flora and the HDL/LPS signaling pathway.PMID:38663104 | DOI:10.1016/j.biopha.2024.116519 (Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie)
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - April 25, 2024 Category: Drugs & Pharmacology Authors: Bo Li Xiao-Feng Jiang Ying-Jie Dong Yi-Piao Zhang Xing-Li-Shang He Cheng-Liang Zhou Yan-Yan Ding Ning Wang Yi-Bin Wang Wan-Qi Cheng Ning-Hua Jiang Jie Su Gui-Yuan Lv Su-Hong Chen Source Type: research
Higher Sugar Intake Associated with Higher Risk of Depression
According to this study.PMID:38661707 | DOI:10.1097/01.NAJ.0001016400.61479.0c (Source: The American Journal of Nursing)
Source: The American Journal of Nursing - April 25, 2024 Category: Nursing Authors: Karen Rosenberg Source Type: research
Molecular simulation on the interaction between trehalose and asymmetric lipid bilayer mimicking the membrane of human red blood cells
In this study, we conducted atomistic molecular dynamic simulations on asymmetric model bilayers that mimic the membrane of human red blood cells at various trehalose and water contents. We considered three different hydration levels mimicking the full hydration to desiccation scenarios. Results indicate that the asymmetric distribution of lipids did not significantly influence the computed structural characteristics at full and low hydration. At dehydration, however, the order parameter obtained from the symmetric bilayer is significantly higher compared to those obtained from asymmetric ones. Analysis of hydrogen bonds r...
Source: Cryobiology - April 25, 2024 Category: Biology Authors: Yu Cao Cai Gao Lei Yang Pei Zhou Dongfang Sun Source Type: research
Higher Sugar Intake Associated with Higher Risk of Depression
According to this study.PMID:38661707 | DOI:10.1097/01.NAJ.0001016400.61479.0c (Source: The American Journal of Nursing)
Source: The American Journal of Nursing - April 25, 2024 Category: Nursing Authors: Karen Rosenberg Source Type: research
Molecular simulation on the interaction between trehalose and asymmetric lipid bilayer mimicking the membrane of human red blood cells
In this study, we conducted atomistic molecular dynamic simulations on asymmetric model bilayers that mimic the membrane of human red blood cells at various trehalose and water contents. We considered three different hydration levels mimicking the full hydration to desiccation scenarios. Results indicate that the asymmetric distribution of lipids did not significantly influence the computed structural characteristics at full and low hydration. At dehydration, however, the order parameter obtained from the symmetric bilayer is significantly higher compared to those obtained from asymmetric ones. Analysis of hydrogen bonds r...
Source: Cryobiology - April 25, 2024 Category: Biology Authors: Yu Cao Cai Gao Lei Yang Pei Zhou Dongfang Sun Source Type: research
