Australian Black Summer smoke signal on Antarctic aerosol collected between New Zealand and the Ross Sea
In this study, five aerosol samples (total suspended particles with a diameter >1 μm) were collected during the XXXV Italian Expedition in Antarctica on board of the R/V Laura Bassi from 6th of January to 16th of February 2020, along the sailing route from Lyttelton harbor (New Zealand) to Terra Nova Bay (Antarctica). Levoglucosan and its isomers have been analyzed as markers of BB, together with polycyclic aromatic hydrocarbons (PAHs), sucrose and alcohol sugars. Ionic species and carboxylic acids have been analyzed to support the identification of aerosol sources and its aging. Results showed high levoglucosan concen...
Source: Chemosphere - April 19, 2024 Category: Chemistry Authors: Elisa Scalabrin Elena Barbaro Sarah Pizzini Marta Radaelli Matteo Feltracco Rossano Piazza Andrea Gambaro Gabriele Capodaglio Source Type: research
Biological evaluation of sulfonate and sulfate analogues of lithocholic acid: A bioisosterism-guided approach towards the discovery of potential sialyltransferase inhibitors for antimetastatic study
Bioorg Med Chem Lett. 2024 Apr 17;105:129760. doi: 10.1016/j.bmcl.2024.129760. Online ahead of print.ABSTRACTThe naturally occurring bile acid lithocholic acid (LCA) has been a crucial core structure for many non-sugar-containing sialyltranferase (ST) inhibitors documented in literature. With the aim of elucidating the impact of the terminal carboxyl acid substituent of LCA on its ST inhibition, in this present study, we report the (bio)isosteric replacement-based design and synthesis of sulfonate and sulfate analogues of LCA. Among these compounds, the sulfate analogue SPP-002 was found to selectively inhibit N-glycan sia...
Source: Bioorganic and Medicinal Chemistry Letters - April 19, 2024 Category: Chemistry Authors: Ser John Lynon P Perez Chia-Ling Chen Tzu-Ting Chang Wen-Shan Li Source Type: research
Australian Black Summer smoke signal on Antarctic aerosol collected between New Zealand and the Ross Sea
In this study, five aerosol samples (total suspended particles with a diameter >1 μm) were collected during the XXXV Italian Expedition in Antarctica on board of the R/V Laura Bassi from 6th of January to 16th of February 2020, along the sailing route from Lyttelton harbor (New Zealand) to Terra Nova Bay (Antarctica). Levoglucosan and its isomers have been analyzed as markers of BB, together with polycyclic aromatic hydrocarbons (PAHs), sucrose and alcohol sugars. Ionic species and carboxylic acids have been analyzed to support the identification of aerosol sources and its aging. Results showed high levoglucosan concen...
Source: Chemosphere - April 19, 2024 Category: Chemistry Authors: Elisa Scalabrin Elena Barbaro Sarah Pizzini Marta Radaelli Matteo Feltracco Rossano Piazza Andrea Gambaro Gabriele Capodaglio Source Type: research
Nutritional Value, Therapeutic Effects, Phytochemistry, and Toxicology of Lepisanthes fruticosa: A Review
Curr Top Med Chem. 2024 Apr 18. doi: 10.2174/0115680266300963240408051156. Online ahead of print.ABSTRACTThe multifaceted benefits of Lepisanthes fruticosa position it is not only as a promising agricultural commodity but also as a versatile resource with implications for health, biodiversity, and economic growth. Lepisanthes fruticosa has a rich history of traditional use for treating various ailments such as fever and diarrhea. Beyond its traditional uses, the plant's antioxidant properties suggest potential applications in combating oxidative stress-related conditions. Its antihyperglycemic properties indicate promise i...
Source: Current Topics in Medicinal Chemistry - April 19, 2024 Category: Chemistry Authors: Lim Joe Siang Harish Rajak Veerasamy Ravichandran Source Type: research
Evaluation of prediabetes patients in terms of metabolic syndrome
CONCLUSIONS: Hypertension, dyslipidemia, abdominal obesity, and metabolic obesity increased in the coexistence of prediabetes and MetS. At the same time, the coexistence of prediabetes and MetS was associated with higher systolic blood pressure, postprandial blood sugar, and LDL levels. Prediabetic individuals accompanied by MetS are at greater metabolic risk.PMID:38639515 | DOI:10.26355/eurrev_202404_35904 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 19, 2024 Category: Drugs & Pharmacology Authors: S Genc B Evren M N Ayd ın I Sahin Source Type: research
Evolution of household availability of added sugars and their sources in Brazil: analysis of Household Budget Surveys from 2002 to 2017
In conclusion, Brazilians' total intake of added sugar was decreased, mostly owing to reduced consumption of sugar from soft drinks.PMID:38634261 | DOI:10.1017/S0007114524000813 (Source: The British Journal of Nutrition)
Source: The British Journal of Nutrition - April 18, 2024 Category: Nutrition Authors: Daniela Silva Canella Maria Laura da Costa Louzada Nat ália Oliveira Ana Beatriz Coelho de Azevedo Renata Bertazzi Levy Source Type: research
Insights into intraspecific diversity of central carbon metabolites in Saccharomyces cerevisiae during wine fermentation
Food Microbiol. 2024 Aug;121:104513. doi: 10.1016/j.fm.2024.104513. Epub 2024 Mar 5.ABSTRACTSaccharomyces cerevisiae is a major actor in winemaking that converts sugars from the grape must into ethanol and CO2 with outstanding efficiency. Primary metabolites produced during fermentation have a great importance in wine. While ethanol content contributes to the overall profile, other metabolites like glycerol, succinate, acetate or lactate also have significant impacts, even when present in lower concentrations. S. cerevisiae is known for its great genetic diversity that is related to its natural or technological environment...
Source: Food Microbiology - April 18, 2024 Category: Food Science Authors: Ludovic Monnin Thibault Nidelet Jessica Noble Virginie Galeote Source Type: research
Investigation of the growth of Listeria in plant-based beverages
The objective of the present study was to evaluate whether the content of sugar, protein, fat, or fibre in commercially available and specially formulated plant-based beverages (oat, soya and pea) influences the growth rates of Listeria. Beverages were inoculated with a strain cocktail of Listeria (approximately 1 × 103 CFU/mL), and the data demonstrated that Listeria could proliferate in all tested beverages. Moreover, varying concentrations of naturally occurring or added sugar (0-3.3%), protein (3.3-5%), fat (1.1-3.5%) and added fibre (0-1.5%) did not have a statistically significant (p > 0.05) impact on the growth ...
Source: Food Microbiology - April 18, 2024 Category: Food Science Authors: Klaudia Bartula Sambou Biagui M áire Begley Michael Callanan Source Type: research
