Bioorthogonal chemistry, the journey from basic science to clinical translation
Part of the Wednesday Afternoon Lecture Series, the lecture is given by a researcher dedicated to advancing and improving the careers of women scientists. Since 1994 when this annual lecture began, every speaker has exemplified the intelligence, scientific excellence and drive that made Margaret Pittman a leader as the first female laboratory chief at NIH.
Professor Carolyn Bertozzi's research interests span the disciplines of chemistry and biology with an emphasis on studies of cell surface sugars important to human health and disease. Her research group profiles changes in cell surface glycosylation associated with ca...
Source: Videocast - All Events - July 19, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
October 2022: EMedHome’s Video with James Ahn, MD: Pour Some Sugar on Me
Dr. Ahn delves into how to treat children with DKA. (Source: Emergency Medicine News - Video)
Source: Emergency Medicine News - Video - September 29, 2022 Category: Databases & Libraries Source Type: video
NIH Glycobiology Special Topics Seminar: Introduction to glycan structures, nomenclature, and glycosylation pathways
This special topics lecture series will provide an overview of the fundamental facts, concepts, and methods concerning glycosylation with an emphasis on aspects relevant to human health and disease.
Glycosylation mediates a wide variety of cellular functions and all multicellular organisms utilize glycans as biosignals in normal physiology. Most mammalian proteins contain sugar chains (referred to as glycans). These glycoproteins are formed as secondary gene products by the concerted action o f glycosyltransferases, glycosidases, and high-energy sugar nucleotides. Therefore, the biosynthesis of glycans is not controlled ...
Source: Videocast - All Events - August 10, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video
Special Topics Seminar Series: Glycosylation in Human Health and Disease [early day 1]
This special topics lecture series will provide an overview of the fundamental facts, concepts, and methods concerning glycosylation with an emphasis on aspects relevant to human health and disease.
Glycosylation mediates a wide variety of cellular functions and all multicellular organisms utilize glycans as biosignals in normal physiology. Most mammalian proteins contain sugar chains (referred to as glycans). These glycoproteins are formed as secondary gene products by the concerted action o f glycosyltransferases, glycosidases, and high-energy sugar nucleotides. Therefore, the biosynthesis of glycans is not controlled ...
Source: Videocast - All Events - July 28, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video
New Tools for Finding Glycans in the PDB & Using the Information to Model 3D Structures of Glycans and GlycoProteins
Glycans play a critical role in nearly all aspects of biology, ranging from how our bodies recognize and fight viruses and bacteria to how proteins are moved throughout our cells to perform different tasks. The Common Fund ’ s Glycoscience program (CF-GSP) is creating new resources, tools, and methods to make the study of glycans (sugars) more accessible to the broader research community. The Protein Data Bank (PDB) contains more than 160,000 3D structures of biological macromolecules 20% of which contain carbohydrates as ligands or as chemical modifications. Unfortunately, much of the PDB's carbohydrate structural data ...
Source: Videocast - All Events - July 28, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
A feat of reverse engineering!
NSF funded researchers @tuftsu have developed a genetically modified yeast that can more efficiently consume a sugar called xylose. Changing the menu for yeast from glucose to xylose can lead to many advances including biofuel production. For more information: (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - June 14, 2018 Category: Science Source Type: video
Sugar and the beating heart: the conundrum of heart failure in diabetes
NIH Director ’ s Wednesday Afternoon Lecture Series
Dr. Abel's current research interests focus on elucidating the molecular mechanisms leading to cardiac dysfunction in diabetes and the regulation of myocardial growth and metabolism by insulin signaling.For more information go tohttps://oir.nih.gov/wals/2017-2018/sugar-beating-heart-conundrum-heart-failure-diabetesAir date: 2/7/2018 3:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - February 5, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
