Bioorthogonal chemistry, the journey from basic science to clinical translation

Part of the Wednesday Afternoon Lecture Series, the lecture is given by a researcher dedicated to advancing and improving the careers of women scientists. Since 1994 when this annual lecture began, every speaker has exemplified the intelligence, scientific excellence and drive that made Margaret Pittman a leader as the first female laboratory chief at NIH. Professor Carolyn Bertozzi's research interests span the disciplines of chemistry and biology with an emphasis on studies of cell surface sugars important to human health and disease. Her research group profiles changes in cell surface glycosylation associated with cancer, inflammation and bacter ial infection, and uses this information to develop new diagnostic and therapeutic approaches, most recently in the area of immuno-oncology. Dr. Bertozzi completed her undergraduate degree in Chemistry at Harvard University and her Ph.D. at UC Berkeley, focusing on the chemical synthesis of oligosa ccharide analogs. During postdoctoral work at UC San Francisco, she studied the activity of endothelial oligosaccharides in promoting cell adhesion at sites of inflammation. She joined the UC Berkeley faculty in 1996. A Howard Hughes Medical Institute Investigator since 2000, she came to Stanford Un iversity in June 2015, among the first faculty to join the interdisciplinary institute ChEM-H (Chemistry, Engineering& Medicine for Human Health). She is now the Baker Family Director of Stanford ChEM-H. Named a MacArthur Fellow in 1999...
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