The crystallization properties of antifreeze GelMA hydrogel and its application in cryopreservation of tissue-engineered skin constructs
J Biomed Mater Res B Appl Biomater. 2024 May;112(5):e35408. doi: 10.1002/jbm.b.35408.ABSTRACTGelatin methacrylate (GelMA) hydrogels are expected to be ideal skin tissue engineering dressings for a wide range of clinical treatments. Herein, we report the preparation of GelMA or antifreeze GelMA hydrogel sheets with different GelMA concentrations, crosslinking times, and cryoprotectant (CPA) concentrations. The crystallization properties of GelMA or antifreeze GelMA hydrogel sheets were studied by cryomicroscopy and differential scanning calorimetry (DSC). It was found that the growth of ice crystals was slower when GelMA hy...
Source: Biomed Res - April 27, 2024 Category: Research Authors: Jia Tan Jiahui Li Xinli Zhou Source Type: research
Epidermoid Cyst of the Maxillary Sinus: A Case Report and Literature Review
We describe a rare case of an epidermoid cyst arising in the right maxillary sinus. A 29-year-old man with a known diagnosis of Marfan syndrome presented with progressive swelling and tenderness in the right buccal region, mimicking facial cellulitis, and refractory to medical treatment. Computed tomography scan showed a cystic lesion extending widely into the right maxillary sinus. The cyst was successfully removed with a medial maxillectomy through inferior antrostomy approach under general anesthesia. Histological examination confirmed the diagnosis of an epidermoid cyst, showing a cystic wall lined with a thin layer of...
Source: Ear, Nose and Throat Journal - April 27, 2024 Category: ENT & OMF Authors: Ivy Yenwen Chau Jiann-Shang Chou Chih-Jen Hsueh Source Type: research
De novo autoimmune connective tissue disease and mortality in patients treated with anti-PD-1 and anti-PD-L1 therapy: a population-level cohort study
Br J Dermatol. 2024 Apr 28:ljae184. doi: 10.1093/bjd/ljae184. Online ahead of print.NO ABSTRACTPMID:38676955 | DOI:10.1093/bjd/ljae184 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 27, 2024 Category: Dermatology Authors: Kimberly Tang Ahmad Rajeh Katharina S Shaw Nga Nguyen Guihong Wan Kimberly B Hashemi Rochelle L Castillo Shawn G Kwatra Nicole R LeBoeuf Ruth Ann Vleugels Yevgeniy R Semenov Source Type: research
Electrosurgery in the treatment of pedunculated rhinophyma
Ann Dermatol Venereol. 2024 Apr 26;151(2):103270. doi: 10.1016/j.annder.2024.103270. Online ahead of print.NO ABSTRACTPMID:38676974 | DOI:10.1016/j.annder.2024.103270 (Source: Annales de Dermatologie et de Cenereologie)
Source: Annales de Dermatologie et de Cenereologie - April 27, 2024 Category: Dermatology Authors: M Dultra P Barros A Ivanchuk J R Pegas Source Type: research
Acceleration of Wound Healing in Diabetic Rats through a Novel 3D Organo-Hydrogel Nanocomposite of Polydopamine/TiO2 Nanoparticles and Cu (PDA-TiO2@Cu)
CONCLUSION: The organo-hydrogel can be used for treating and decreasing the healing period of diabetic wounds.PMID:38676522 | DOI:10.2174/0118715303280532240415094718 (Source: Endocrine, Metabolic and Immune Disorders Drug Targets)
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - April 27, 2024 Category: Endocrinology Authors: Sally A Elekhtiar Maha Mohamed Abo Gazia Azza I Helal Hala Mahfouz Nesma M El-Kemary Sherief Abd-Elsalam Samar Elksass Hend A Alkabes Maged El-Kemary Marwa M Abd-Elsalam Source Type: research
Severe BCG immune reconstitution inflammatory syndrome lymphadenitis successfully managed with pre-antiretroviral counseling and a non-surgical approach: a case report
CONCLUSIONS: This case details the successful management of severe suppurative BCG-IRIS with a non-surgical approach and underlines the importance of pre-ART counseling on BCG-IRIS for caregivers, particularly for infants who initiate ART with advanced HIV.PMID:38678293 | PMC:PMC11056047 | DOI:10.1186/s12981-024-00614-7 (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - April 27, 2024 Category: Infectious Diseases Authors: Percina Machava Winete Joaquim Joseph Borrell Shannon Richardson Uneisse Cassia Muhammad Sidat Alice Maieca Cl áudia Massitela Yara Quelhas Cafrina Mucuila Beatriz Elias Massada da Rocha H Simon Schaaf W Chris Buck Source Type: research
The Influence of Inset and Shaping of Abdominal-Based Free Flap Breast Reconstruction on Patient-Reported Aesthetic Outcome Scores-A Systematic Review
Conclusions: Emphasis on the aesthetic outcome in terms of breast shape and symmetry, providing an individualized approach of flap inset, considering the contralateral breast's shape and volume, results in higher satisfaction scores.PMID:38673668 | PMC:PMC11051228 | DOI:10.3390/jcm13082395 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - April 27, 2024 Category: Cancer & Oncology Authors: Isabel Zucal Laura De Pellegrin Corrado Parodi Yves Harder Riccardo Schweizer Source Type: research
The Influence of Inset and Shaping of Abdominal-Based Free Flap Breast Reconstruction on Patient-Reported Aesthetic Outcome Scores-A Systematic Review
Conclusions: Emphasis on the aesthetic outcome in terms of breast shape and symmetry, providing an individualized approach of flap inset, considering the contralateral breast's shape and volume, results in higher satisfaction scores.PMID:38673668 | PMC:PMC11051228 | DOI:10.3390/jcm13082395 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - April 27, 2024 Category: Cancer & Oncology Authors: Isabel Zucal Laura De Pellegrin Corrado Parodi Yves Harder Riccardo Schweizer Source Type: research
Patients' and Caregivers' Experiences Navigating the Burden of Atopic Dermatitis in Argentina
Discussion: Mental health, pain/discomfort, and financial worries are the most important burdens for adult AD patients and caregivers of children with AD in Argentina. We recommend prioritizing disease-specific education and shared decision making to improve AD care in Argentina.PMID:38674230 | PMC:PMC11052293 | DOI:10.3390/medicina60040584 (Source: Pain Physician)
Source: Pain Physician - April 27, 2024 Category: Anesthesiology Authors: Korey Capozza Michelle Tu Alan Schwartz Jodi L Johnson M ónica Ladner Source Type: research
Immunolabeling for filaggrin and acidic keratins in the granular layer of mammalian epidermis indicates that an acidic-basic interaction is involved in cornification
Tissue Cell. 2024 Apr 25;88:102397. doi: 10.1016/j.tice.2024.102397. Online ahead of print.ABSTRACTThe soft epidermis of mammals derives from the accumulation of keratohyaline granules in the granular layer, before maturing into corneocytes. Main proteins accumulated in the granular layer are pro-filaggrin and filaggrin that determine keratin clumping and later moisturization of the stratum corneum that remains flexible. This soft epidermis allows the high sensitivity of mammalian skin. Presence and thickness of the stratum granulosum varies among different species of mammals and even between different body regions of the ...
Source: Tissue and Cell - April 27, 2024 Category: Cytology Authors: Lorenzo Alibardi Source Type: research
A Pharmacovigilance Study of adverse events associated with polymyxins based on the U.S. Food and Drug Administration adverse event reporting system (FAERS) database
CONCLUSIONS: Patients treated with colistin displayed a higher potential risk of nephrotoxicity but a lower risk of neurotoxicity when compared to those treated with PMB. Clinicians should be vigilant in monitoring the AEs of hyperpigmentation disorders induced by PMB, as there have been reported cases associated with its use, whereas no instances of this AE were reported among colistin-treated patients. Nevertheless, further research, especially with larger sample sizes, is imperative to validate these findings.PMID:38676603 | DOI:10.1080/14740338.2024.2348610 (Source: Expert Opinion on Drug Safety)
Source: Expert Opinion on Drug Safety - April 27, 2024 Category: Drugs & Pharmacology Authors: Tingxi Wu Yanfeng Shi Chang Xu Bin Zhu Dandan Li Zhe Li Zhigang Zhao Yang Zhang Source Type: research
Kreotoxin A administration inhibits hyperproliferation and inflammation of human ear keloid tissue and keloid-derived fibroblasts by downregulating HIF-1 α expression
In conclusion, our findings provide novel insights into the mechanisms of action of KTA as a potential therapeutic agent for keloids via modulating HIF-1α expression.PMID:38676999 | DOI:10.1016/j.bbrc.2024.149963 (Source: Biochemical and Biophysical Research communications)
Source: Biochemical and Biophysical Research communications - April 27, 2024 Category: Biochemistry Authors: Hua Guo Qingmei Guo Zhilin Ma Source Type: research
Proximity to Dermatological Care for Patients Living in Ontario's Rural Communities: A Cross-Sectional Analysis
J Cutan Med Surg. 2024 Apr 27:12034754241247529. doi: 10.1177/12034754241247529. Online ahead of print.NO ABSTRACTPMID:38676559 | DOI:10.1177/12034754241247529 (Source: Rural Remote Health)
Source: Rural Remote Health - April 27, 2024 Category: Rural Health Authors: Eric McMullen Xi Yao Gui Kyle Storm Rajan Grewal Ilya Mukovozov Source Type: research
Acceleration of Wound Healing in Diabetic Rats through a Novel 3D Organo-Hydrogel Nanocomposite of Polydopamine/TiO2 Nanoparticles and Cu (PDA-TiO2@Cu)
CONCLUSION: The organo-hydrogel can be used for treating and decreasing the healing period of diabetic wounds.PMID:38676522 | DOI:10.2174/0118715303280532240415094718 (Source: Endocrine, Metabolic and Immune Disorders Drug Targets)
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - April 27, 2024 Category: Drugs & Pharmacology Authors: Sally A Elekhtiar Maha Mohamed Abo Gazia Azza I Helal Hala Mahfouz Nesma M El-Kemary Sherief Abd-Elsalam Samar Elksass Hend A Alkabes Maged El-Kemary Marwa M Abd-Elsalam Source Type: research
Hues of risk: investigating genotoxicity and environmental impacts of azo textile dyes
Environ Sci Pollut Res Int. 2024 Apr 27. doi: 10.1007/s11356-024-33444-1. Online ahead of print.ABSTRACTThe textile industry, with its extensive use of dyes and chemicals, stands out as a significant source of water pollution. Exposure to certain textile dyes, such as azo dyes and their breakdown products like aromatic amines, has been associated with health concerns like skin sensitization, allergic reactions, and even cancer in humans. Annually, the worldwide production of synthetic dyes approximates 7 × 107 tons, of which the textile industry accounts for over 10,000 tons. Inefficient dyeing procedures result in the di...
Source: Environmental Science and Pollution Research International - April 27, 2024 Category: Environmental Health Authors: Karthikeyan Ramamurthy Peter Snega Priya Raghul Murugan Jesu Arockiaraj Source Type: research
