Antiracism plan in dermatology
Br J Dermatol. 2021 Apr 16. doi: 10.1111/bjd.20390. Online ahead of print.ABSTRACTThe world has witnessed a crucial resurgence of racial equity movements following the highly publicized deaths of George Floyd, Breonna Taylor and Ahmaud Arbery, among others. This police violence re-exposed the omnipresent, racially oppressive power structure that is the governing foundation of Western and postcolonial society.PMID:33864243 | DOI:10.1111/bjd.20390 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 17, 2021 Category: Dermatology Authors: C Ortiz E Herman A J James Source Type: research

A Clinical and Biologic Review of Keratoacanthoma
Br J Dermatol. 2021 Apr 16. doi: 10.1111/bjd.20389. Online ahead of print.ABSTRACTKeratoacanthoma (KA) is a common skin tumor that remains controversial regarding classification, epidemiology, diagnosis, prognosis, and management. Classically, a KA manifests as a rapidly growing, well-differentiated, squamoid lesion with a predilection for sun-exposed sites in the elderly and a tendency to spontaneously regress. Historically, KAs have been considered a variant of cutaneous squamous cell carcinoma (cSCC) and are often reported as KA-type cSCC. However, the penchant for regression has led many to categorize KAs as biological...
Source: The British Journal of Dermatology - April 17, 2021 Category: Dermatology Authors: A Tisack A Fotouhi C Fidai B J Friedman D Ozog J Veenstra Source Type: research

Clinical experience and psychometric properties of the Cardiff Acne Disability Index (CADI)
Br J Dermatol. 2021 Apr 16. doi: 10.1111/bjd.20391. Online ahead of print.ABSTRACTThe Cardiff Acne Disability Index (CADI) is a questionnaire designed to measure the quality of life (QoL) of teenagers and young adults with acne. It has been used clinically and within therapeutic research globally. This review aims to appraise all published data regarding the clinical and research experience of CADI, its psychometric properties and validation, from its publication in 1992 until September 2020, into a single reference source. A literature search was conducted using Medline via Ovid, PubMed, EBSCOhost, Web of Science and Scop...
Source: The British Journal of Dermatology - April 17, 2021 Category: Dermatology Authors: Y T Abdelrazik F M Ali M S Salek A Y Finlay Source Type: research

Not all melanomas are created equal: A review and call for more research into nodular melanoma
Br J Dermatol. 2021 Apr 16. doi: 10.1111/bjd.20388. Online ahead of print.ABSTRACTAmong the histogenic subtypes of melanoma, nodular melanoma (NM) is the major contributor for thicker and fatal melanomas and it has been associated with melanoma-specific death in thin tumours highlighting an important subgroup of 'aggressive thin' melanomas. This review provides a synthesis of the distinct characteristics of NM, with respect to epidemiology and risk factors, clinical presentation, histopathology, molecular and dermoscopic aspects, and screening practices. The real challenges are to find better biomarkers of aggressiveness a...
Source: The British Journal of Dermatology - April 17, 2021 Category: Dermatology Authors: C Dessinioti A C Geller D C Whiteman C Garbe J J Grob J W Kelly R A Scolyer R V Rawson A Lallas G Pellacani A J Stratigos Source Type: research

Antiracism plan in dermatology
Br J Dermatol. 2021 Apr 16. doi: 10.1111/bjd.20390. Online ahead of print.ABSTRACTThe world has witnessed a crucial resurgence of racial equity movements following the highly publicized deaths of George Floyd, Breonna Taylor and Ahmaud Arbery, among others. This police violence re-exposed the omnipresent, racially oppressive power structure that is the governing foundation of Western and postcolonial society.PMID:33864243 | DOI:10.1111/bjd.20390 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 17, 2021 Category: Dermatology Authors: C Ortiz E Herman A J James Source Type: research

A Clinical and Biologic Review of Keratoacanthoma
Br J Dermatol. 2021 Apr 16. doi: 10.1111/bjd.20389. Online ahead of print.ABSTRACTKeratoacanthoma (KA) is a common skin tumor that remains controversial regarding classification, epidemiology, diagnosis, prognosis, and management. Classically, a KA manifests as a rapidly growing, well-differentiated, squamoid lesion with a predilection for sun-exposed sites in the elderly and a tendency to spontaneously regress. Historically, KAs have been considered a variant of cutaneous squamous cell carcinoma (cSCC) and are often reported as KA-type cSCC. However, the penchant for regression has led many to categorize KAs as biological...
Source: The British Journal of Dermatology - April 17, 2021 Category: Dermatology Authors: A Tisack A Fotouhi C Fidai B J Friedman D Ozog J Veenstra Source Type: research

Clinical experience and psychometric properties of the Cardiff Acne Disability Index (CADI)
Br J Dermatol. 2021 Apr 16. doi: 10.1111/bjd.20391. Online ahead of print.ABSTRACTThe Cardiff Acne Disability Index (CADI) is a questionnaire designed to measure the quality of life (QoL) of teenagers and young adults with acne. It has been used clinically and within therapeutic research globally. This review aims to appraise all published data regarding the clinical and research experience of CADI, its psychometric properties and validation, from its publication in 1992 until September 2020, into a single reference source. A literature search was conducted using Medline via Ovid, PubMed, EBSCOhost, Web of Science and Scop...
Source: The British Journal of Dermatology - April 17, 2021 Category: Dermatology Authors: Y T Abdelrazik F M Ali M S Salek A Y Finlay Source Type: research

Not all melanomas are created equal: A review and call for more research into nodular melanoma
Br J Dermatol. 2021 Apr 16. doi: 10.1111/bjd.20388. Online ahead of print.ABSTRACTAmong the histogenic subtypes of melanoma, nodular melanoma (NM) is the major contributor for thicker and fatal melanomas and it has been associated with melanoma-specific death in thin tumours highlighting an important subgroup of 'aggressive thin' melanomas. This review provides a synthesis of the distinct characteristics of NM, with respect to epidemiology and risk factors, clinical presentation, histopathology, molecular and dermoscopic aspects, and screening practices. The real challenges are to find better biomarkers of aggressiveness a...
Source: The British Journal of Dermatology - April 17, 2021 Category: Dermatology Authors: C Dessinioti A C Geller D C Whiteman C Garbe J J Grob J W Kelly R A Scolyer R V Rawson A Lallas G Pellacani A J Stratigos Source Type: research

Association of gender and systemic therapy treatment outcomes in psoriasis: a two-country, multi-centre, prospective, non-interventional registry study
CONCLUSION: Our data provide evidence that women experience better treatment outcome as measured by PASI to systemic anti-psoriatic therapy than men. Several factors may contribute to this observation, including adherence to treatment, weight, or different lifestyle behavior.PMID:33837519 | DOI:10.1111/bjd.20387 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 10, 2021 Category: Dermatology Authors: J-T Maul M Augustin C Sorbe C Conrad F Anzengruber U Mrowietz K Reich L E French M Radtke P H äusermann L V Maul W-H Boehncke D Tha çi A A Navarini Source Type: research

Outcomes of COVID-19 in Patients with Skin Cancer
Br J Dermatol. 2021 Apr 10. doi: 10.1111/bjd.20386. Online ahead of print.ABSTRACTThe effect of skin cancer diagnosis on the risk of adverse outcomes from COVID-19 remains unknown. Few studies have shown cancer patients with COVID-19 have higher rates of mortality and hospitalizations compared to those without cancer, perhaps due to a combination of delayed diagnosis and pre-existing comorbidities from chemotherapy and radiation treatments.1.PMID:33837520 | DOI:10.1111/bjd.20386 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 10, 2021 Category: Dermatology Authors: R Raiker H Pakhchanian A Hussain M Deng Source Type: research

Decline in use of phototherapy in France from 2010 to 2019
Br J Dermatol. 2021 Apr 9. doi: 10.1111/bjd.20384. Online ahead of print.ABSTRACTSince 2000, targeted therapies (TT) have revolutionized the management of psoriasis and more recently atopic dermatitis, the second main indication for phototherapy. They are now considered as an alternative to conventional treatments. Fears surrounding the introduction of TT have been thought to have decreased demand for phototherapy. However, little is known about recent trends in real-world use of phototherapy.PMID:33837522 | DOI:10.1111/bjd.20384 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 10, 2021 Category: Dermatology Authors: F Aubin C Chaignot I Gallais-Serezal Soci été Française de Photodermatologie Source Type: research

Immediate Global Support is Needed for Myanmar
Br J Dermatol. 2021 Apr 9. doi: 10.1111/bjd.20385. Online ahead of print.ABSTRACTMyanmar (Burma) is a Southeast Asian country that suffered over 50 years of military dictatorship with global isolation and systematic disinvestment in the public sector. This resulted in one of the poorest healthcare systems in the world, with limited or no access to skincare, particularly for disadvantaged communities. The transition of the country to a civilian government in 2011 initiated notable progress in healthcare with strategic plans to develop universal health coverage.PMID:33837524 | DOI:10.1111/bjd.20385 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 10, 2021 Category: Dermatology Authors: S M Lwin C E M Griffiths Source Type: research

Association of gender and systemic therapy treatment outcomes in psoriasis: a two-country, multi-centre, prospective, non-interventional registry study
CONCLUSION: Our data provide evidence that women experience better treatment outcome as measured by PASI to systemic anti-psoriatic therapy than men. Several factors may contribute to this observation, including adherence to treatment, weight, or different lifestyle behavior.PMID:33837519 | DOI:10.1111/bjd.20387 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 10, 2021 Category: Dermatology Authors: J-T Maul M Augustin C Sorbe C Conrad F Anzengruber U Mrowietz K Reich L E French M Radtke P H äusermann L V Maul W-H Boehncke D Tha çi A A Navarini Source Type: research

Outcomes of COVID-19 in Patients with Skin Cancer
Br J Dermatol. 2021 Apr 10. doi: 10.1111/bjd.20386. Online ahead of print.ABSTRACTThe effect of skin cancer diagnosis on the risk of adverse outcomes from COVID-19 remains unknown. Few studies have shown cancer patients with COVID-19 have higher rates of mortality and hospitalizations compared to those without cancer, perhaps due to a combination of delayed diagnosis and pre-existing comorbidities from chemotherapy and radiation treatments.1.PMID:33837520 | DOI:10.1111/bjd.20386 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 10, 2021 Category: Dermatology Authors: R Raiker H Pakhchanian A Hussain M Deng Source Type: research

Decline in use of phototherapy in France from 2010 to 2019
Br J Dermatol. 2021 Apr 9. doi: 10.1111/bjd.20384. Online ahead of print.ABSTRACTSince 2000, targeted therapies (TT) have revolutionized the management of psoriasis and more recently atopic dermatitis, the second main indication for phototherapy. They are now considered as an alternative to conventional treatments. Fears surrounding the introduction of TT have been thought to have decreased demand for phototherapy. However, little is known about recent trends in real-world use of phototherapy.PMID:33837522 | DOI:10.1111/bjd.20384 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 10, 2021 Category: Dermatology Authors: F Aubin C Chaignot I Gallais-Serezal Soci été Française de Photodermatologie Source Type: research

Immediate Global Support is Needed for Myanmar
Br J Dermatol. 2021 Apr 9. doi: 10.1111/bjd.20385. Online ahead of print.ABSTRACTMyanmar (Burma) is a Southeast Asian country that suffered over 50 years of military dictatorship with global isolation and systematic disinvestment in the public sector. This resulted in one of the poorest healthcare systems in the world, with limited or no access to skincare, particularly for disadvantaged communities. The transition of the country to a civilian government in 2011 initiated notable progress in healthcare with strategic plans to develop universal health coverage.PMID:33837524 | DOI:10.1111/bjd.20385 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 10, 2021 Category: Dermatology Authors: S M Lwin C E M Griffiths Source Type: research

Association of gender and systemic therapy treatment outcomes in psoriasis: a two-country, multi-centre, prospective, non-interventional registry study
CONCLUSION: Our data provide evidence that women experience better treatment outcome as measured by PASI to systemic anti-psoriatic therapy than men. Several factors may contribute to this observation, including adherence to treatment, weight, or different lifestyle behavior.PMID:33837519 | DOI:10.1111/bjd.20387 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 10, 2021 Category: Dermatology Authors: J-T Maul M Augustin C Sorbe C Conrad F Anzengruber U Mrowietz K Reich L E French M Radtke P H äusermann L V Maul W-H Boehncke D Tha çi A A Navarini Source Type: research

Outcomes of COVID-19 in Patients with Skin Cancer
Br J Dermatol. 2021 Apr 10. doi: 10.1111/bjd.20386. Online ahead of print.ABSTRACTThe effect of skin cancer diagnosis on the risk of adverse outcomes from COVID-19 remains unknown. Few studies have shown cancer patients with COVID-19 have higher rates of mortality and hospitalizations compared to those without cancer, perhaps due to a combination of delayed diagnosis and pre-existing comorbidities from chemotherapy and radiation treatments.1.PMID:33837520 | DOI:10.1111/bjd.20386 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 10, 2021 Category: Dermatology Authors: R Raiker H Pakhchanian A Hussain M Deng Source Type: research

Decline in use of phototherapy in France from 2010 to 2019
Br J Dermatol. 2021 Apr 9. doi: 10.1111/bjd.20384. Online ahead of print.ABSTRACTSince 2000, targeted therapies (TT) have revolutionized the management of psoriasis and more recently atopic dermatitis, the second main indication for phototherapy. They are now considered as an alternative to conventional treatments. Fears surrounding the introduction of TT have been thought to have decreased demand for phototherapy. However, little is known about recent trends in real-world use of phototherapy.PMID:33837522 | DOI:10.1111/bjd.20384 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 10, 2021 Category: Dermatology Authors: F Aubin C Chaignot I Gallais-Serezal Soci été Française de Photodermatologie Source Type: research

Immediate Global Support is Needed for the Myanmar Dermatology Community
Br J Dermatol. 2021 Apr 9. doi: 10.1111/bjd.20385. Online ahead of print.ABSTRACTMyanmar (Burma) is a Southeast Asian country that suffered over 50 years of military dictatorship with global isolation and systematic disinvestment in the public sector. This resulted in one of the poorest healthcare systems in the world, with limited or no access to skincare, particularly for disadvantaged communities. The transition of the country to a civilian government in 2011 initiated notable progress in healthcare with strategic plans to develop universal health coverage.1.PMID:33837524 | DOI:10.1111/bjd.20385 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 10, 2021 Category: Dermatology Authors: S M Lwin C E M Griffiths Source Type: research

Association of gender and systemic therapy treatment outcomes in psoriasis: a two-country, multi-centre, prospective, non-interventional registry study
CONCLUSION: Our data provide evidence that women experience better treatment outcome as measured by PASI to systemic anti-psoriatic therapy than men. Several factors may contribute to this observation, including adherence to treatment, weight, or different lifestyle behavior.PMID:33837519 | DOI:10.1111/bjd.20387 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 10, 2021 Category: Dermatology Authors: J-T Maul M Augustin C Sorbe C Conrad F Anzengruber U Mrowietz K Reich L E French M Radtke P H äusermann L V Maul W-H Boehncke D Tha çi A A Navarini Source Type: research

Outcomes of COVID-19 in Patients with Skin Cancer
Br J Dermatol. 2021 Apr 10. doi: 10.1111/bjd.20386. Online ahead of print.ABSTRACTThe effect of skin cancer diagnosis on the risk of adverse outcomes from COVID-19 remains unknown. Few studies have shown cancer patients with COVID-19 have higher rates of mortality and hospitalizations compared to those without cancer, perhaps due to a combination of delayed diagnosis and pre-existing comorbidities from chemotherapy and radiation treatments.1.PMID:33837520 | DOI:10.1111/bjd.20386 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 10, 2021 Category: Dermatology Authors: R Raiker H Pakhchanian A Hussain M Deng Source Type: research

Decline in use of phototherapy in France from 2010 to 2019
Br J Dermatol. 2021 Apr 9. doi: 10.1111/bjd.20384. Online ahead of print.ABSTRACTSince 2000, targeted therapies (TT) have revolutionized the management of psoriasis and more recently atopic dermatitis, the second main indication for phototherapy. They are now considered as an alternative to conventional treatments. Fears surrounding the introduction of TT have been thought to have decreased demand for phototherapy. However, little is known about recent trends in real-world use of phototherapy.PMID:33837522 | DOI:10.1111/bjd.20384 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 10, 2021 Category: Dermatology Authors: F Aubin C Chaignot I Gallais-Serezal Soci été Française de Photodermatologie Source Type: research

Immediate Global Support is Needed for the Myanmar Dermatology Community
Br J Dermatol. 2021 Apr 9. doi: 10.1111/bjd.20385. Online ahead of print.ABSTRACTMyanmar (Burma) is a Southeast Asian country that suffered over 50 years of military dictatorship with global isolation and systematic disinvestment in the public sector. This resulted in one of the poorest healthcare systems in the world, with limited or no access to skincare, particularly for disadvantaged communities. The transition of the country to a civilian government in 2011 initiated notable progress in healthcare with strategic plans to develop universal health coverage.1.PMID:33837524 | DOI:10.1111/bjd.20385 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 10, 2021 Category: Dermatology Authors: S M Lwin C E M Griffiths Source Type: research

Association of gender and systemic therapy treatment outcomes in psoriasis: a two-country, multi-centre, prospective, non-interventional registry study
CONCLUSION: Our data provide evidence that women experience better treatment outcome as measured by PASI to systemic anti-psoriatic therapy than men. Several factors may contribute to this observation, including adherence to treatment, weight, or different lifestyle behavior.PMID:33837519 | DOI:10.1111/bjd.20387 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 10, 2021 Category: Dermatology Authors: J-T Maul M Augustin C Sorbe C Conrad F Anzengruber U Mrowietz K Reich L E French M Radtke P H äusermann L V Maul W-H Boehncke D Tha çi A A Navarini Source Type: research

Outcomes of COVID-19 in Patients with Skin Cancer
Br J Dermatol. 2021 Apr 10. doi: 10.1111/bjd.20386. Online ahead of print.ABSTRACTThe effect of skin cancer diagnosis on the risk of adverse outcomes from COVID-19 remains unknown. Few studies have shown cancer patients with COVID-19 have higher rates of mortality and hospitalizations compared to those without cancer, perhaps due to a combination of delayed diagnosis and pre-existing comorbidities from chemotherapy and radiation treatments.1.PMID:33837520 | DOI:10.1111/bjd.20386 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 10, 2021 Category: Dermatology Authors: R Raiker H Pakhchanian A Hussain M Deng Source Type: research

Decline in use of phototherapy in France from 2010 to 2019
Br J Dermatol. 2021 Apr 9. doi: 10.1111/bjd.20384. Online ahead of print.ABSTRACTSince 2000, targeted therapies (TT) have revolutionized the management of psoriasis and more recently atopic dermatitis, the second main indication for phototherapy. They are now considered as an alternative to conventional treatments. Fears surrounding the introduction of TT have been thought to have decreased demand for phototherapy. However, little is known about recent trends in real-world use of phototherapy.PMID:33837522 | DOI:10.1111/bjd.20384 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 10, 2021 Category: Dermatology Authors: F Aubin C Chaignot I Gallais-Serezal Soci été Française de Photodermatologie Source Type: research

Immediate Global Support is Needed for the Myanmar Dermatology Community
Br J Dermatol. 2021 Apr 9. doi: 10.1111/bjd.20385. Online ahead of print.ABSTRACTMyanmar (Burma) is a Southeast Asian country that suffered over 50 years of military dictatorship with global isolation and systematic disinvestment in the public sector. This resulted in one of the poorest healthcare systems in the world, with limited or no access to skincare, particularly for disadvantaged communities. The transition of the country to a civilian government in 2011 initiated notable progress in healthcare with strategic plans to develop universal health coverage.1.PMID:33837524 | DOI:10.1111/bjd.20385 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 10, 2021 Category: Dermatology Authors: S M Lwin C E M Griffiths Source Type: research

Association of gender and systemic therapy treatment outcomes in psoriasis: a two-country, multi-centre, prospective, non-interventional registry study
CONCLUSION: Our data provide evidence that women experience better treatment outcome as measured by PASI to systemic anti-psoriatic therapy than men. Several factors may contribute to this observation, including adherence to treatment, weight, or different lifestyle behavior.PMID:33837519 | DOI:10.1111/bjd.20387 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 10, 2021 Category: Dermatology Authors: J-T Maul M Augustin C Sorbe C Conrad F Anzengruber U Mrowietz K Reich L E French M Radtke P H äusermann L V Maul W-H Boehncke D Tha çi A A Navarini Source Type: research

Outcomes of COVID-19 in Patients with Skin Cancer
Br J Dermatol. 2021 Apr 10. doi: 10.1111/bjd.20386. Online ahead of print.ABSTRACTThe effect of skin cancer diagnosis on the risk of adverse outcomes from COVID-19 remains unknown. Few studies have shown cancer patients with COVID-19 have higher rates of mortality and hospitalizations compared to those without cancer, perhaps due to a combination of delayed diagnosis and pre-existing comorbidities from chemotherapy and radiation treatments.1.PMID:33837520 | DOI:10.1111/bjd.20386 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 10, 2021 Category: Dermatology Authors: R Raiker H Pakhchanian A Hussain M Deng Source Type: research

Decline in use of phototherapy in France from 2010 to 2019
Br J Dermatol. 2021 Apr 9. doi: 10.1111/bjd.20384. Online ahead of print.ABSTRACTSince 2000, targeted therapies (TT) have revolutionized the management of psoriasis and more recently atopic dermatitis, the second main indication for phototherapy. They are now considered as an alternative to conventional treatments. Fears surrounding the introduction of TT have been thought to have decreased demand for phototherapy. However, little is known about recent trends in real-world use of phototherapy.PMID:33837522 | DOI:10.1111/bjd.20384 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 10, 2021 Category: Dermatology Authors: F Aubin C Chaignot I Gallais-Serezal Soci été Française de Photodermatologie Source Type: research

Immediate Global Support is Needed for the Myanmar Dermatology Community
Br J Dermatol. 2021 Apr 9. doi: 10.1111/bjd.20385. Online ahead of print.ABSTRACTMyanmar (Burma) is a Southeast Asian country that suffered over 50 years of military dictatorship with global isolation and systematic disinvestment in the public sector. This resulted in one of the poorest healthcare systems in the world, with limited or no access to skincare, particularly for disadvantaged communities. The transition of the country to a civilian government in 2011 initiated notable progress in healthcare with strategic plans to develop universal health coverage.1.PMID:33837524 | DOI:10.1111/bjd.20385 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 10, 2021 Category: Dermatology Authors: S M Lwin C E M Griffiths Source Type: research

Ultraviolet A Radiation and COVID-19 Deaths in the USA with replication studies in England and Italy
CONCLUSIONS: Our analysis suggests that higher ambient UVA exposure is associated with lower COVID-19 specific mortality. Further research on the mechanism may indicate novel treatments. Optimised UVA exposure may have population health benefits.PMID:33834487 | DOI:10.1111/bjd.20093 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 9, 2021 Category: Dermatology Authors: M Cherrie T Clemens C Colandrea Z Feng D J Webb R B Weller C Dibben Source Type: research

What is the best surgical treatment for dermatofibrosarcoma protuberans?
This study was carried out at several centres in the UK. Clinical records were examined of cases of DFSP between 1 January 2004 and 31 December 2013. This study includes the largest number of cases of DFSP reported in the UK: 483 new and 64 recurring cases of DFSP, in 11 plastic surgery and 15 dermatology departments. The methods used to perform these 547 surgeries were analysed. Almost 75% of cases of new DFSP were treated with WLE and 20% were treated with MMS. For recurring DFSP, 69% of patients had WLE and 23% had MMS. After a median follow-up period of just over 2 years for new DFSP and 1.6 years for recurring DFSP, t...
Source: The British Journal of Dermatology - April 9, 2021 Category: Dermatology Source Type: research

Navigating social media: the BJD experience
Br J Dermatol. 2021 Apr;184(4):585-586. doi: 10.1111/bjd.19754.NO ABSTRACTPMID:33835486 | DOI:10.1111/bjd.19754 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 9, 2021 Category: Dermatology Authors: J Guckian C Cotter M Charalambides N Kibbi Source Type: research

BJD Reviewers January 2020 - December 2020
Br J Dermatol. 2021 Apr;184(4):777-785. doi: 10.1111/bjd.19859.NO ABSTRACTPMID:33835487 | DOI:10.1111/bjd.19859 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 9, 2021 Category: Dermatology Source Type: research

The risk of malignancy in secukinumab-treated psoriasis, psoriatic arthritis and ankylosing spondylitis patients: analysis of up to five-year clinical trial and post-marketing surveillance data
CONCLUSIONS: In this large safety analysis, the risk of malignancy was low for up to five years of secukinumab treatment. These data support the long-term us of secukinumab in these indications.PMID:33829482 | DOI:10.1111/bjd.20136 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 8, 2021 Category: Dermatology Authors: M Lebwohl A Deodhar C E M Griffiths M A Menter D Poddubnyy W Bao V Jehl K Marfo P Primatesta A Shete V Trivedi P J Mease Source Type: research

Cutaneous squamous cell carcinoma is associated with Lynch syndrome; widening the spectrum of Lynch syndrome associated tumours
Br J Dermatol. 2021 Apr 7. doi: 10.1111/bjd.20139. Online ahead of print.ABSTRACTDear Editor, Lynch syndrome (LS) is caused by a germline mutation in one of the mismatch repair (MMR) genes. Individuals with LS have an increased risk of developing colorectal and many other tumours including skin tumours.1 Sebaceous neoplasms and keratoacanthomas are skin tumours associated with LS, also known as Muir-Torre syndrome. For cutaneous squamous cell carcinoma (SCC), an association with LS has been suggested.PMID:33829484 | DOI:10.1111/bjd.20139 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 8, 2021 Category: Dermatology Authors: B L M Ykema F Adan M B Crijns F E Bleeker E Dekker M W Bekkenk P Snaebjornsson M E van Leerdam Source Type: research

Novel light-dependent and light-independent functions of opsin 5
Br J Dermatol. 2021 Apr 7. doi: 10.1111/bjd.20052. Online ahead of print.NO ABSTRACTPMID:33829486 | DOI:10.1111/bjd.20052 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 8, 2021 Category: Dermatology Authors: L V M de Assis A M L Castrucci Source Type: research

Defining Trajectories of Response in Psoriasis Patients Treated with Biologic Therapies
CONCLUSION: These subgroups, defined by change in disease over time, may be indicative of distinct endotypes driven by different biological mechanisms and may help inform the management of patients with psoriasis. Future work will aim to further delineate these mechanisms by extensively characterising the subgroups with additional molecular and pharmacological data.PMID:33829489 | DOI:10.1111/bjd.20140 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 8, 2021 Category: Dermatology Authors: N Geifman N Azadbakht J Zeng T Wilkinson N Dand I Buchan D Stocken P Di Meglio R B Warren J N Barker N J Reynolds M R Barnes C H Smith C E M Griffiths N Peek BADBIR Study Group, on behalf of the PSORT Consortium Source Type: research

Efficacy of S-1 plus docetaxel in the treatment of metastatic extramammary Paget's disease: a multicentre retrospective study
Br J Dermatol. 2021 Apr 8. doi: 10.1111/bjd.20135. Online ahead of print.ABSTRACTMetastatic extramammary Paget's disease (EMPD) is an intractable condition that is refractory to conventional treatments and the outcomes remain unsatisfactory1 . Establishing an effective regimen with higher response rates and long-term efficacy is required.PMID:33829494 | DOI:10.1111/bjd.20135 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 8, 2021 Category: Dermatology Authors: S Matsushita K Fujii I Kajihara M Aoki K Yamamura K Tada T Kanekura J Aoi S Fukushima Source Type: research

Dupilumab-associated arthralgia: an observational retrospective study in VigiBase ®
Br J Dermatol. 2021 Apr 7. doi: 10.1111/bjd.20138. Online ahead of print.ABSTRACTDear Editor, Dupilumab is a human monoclonal antibody that blocks the shared receptor unit for interleukin (IL)-4 and IL-13, and is approved in several indications, including moderate-to-severe atopic dermatitis (AD). According to a recent meta-analysis dupilumab treatment versus placebo resulted in a significant increase in the number of patients who achieved Eczema Area and Severity Index-75 (Rate-Ratio 3.09; 95% CI 2.45-3.89) in different ethnical populations.PMID:33829495 | DOI:10.1111/bjd.20138 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 8, 2021 Category: Dermatology Authors: B Chr étien C Dolladille J Alexandre S Fedrizzi V Lelong-Boulouard J C Lambert E Ezine Source Type: research

Automated detection of skin reactions in epicutaneous patch testing using machine learning
Br J Dermatol. 2021 Apr 7. doi: 10.1111/bjd.20141. Online ahead of print.ABSTRACTPatch testing is the diagnostic gold standard to identify causes of allergic contact dermatitis (ACD); however, the paucity of specialized patch testing clinics along with the need for multiple clinic visits can be burdensome for patients and healthcare systems. Automated classification of allergic reactions from photographs offers the opportunity to reduce patient, physician, and clinic time and improve access to care.PMID:33829497 | DOI:10.1111/bjd.20141 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 8, 2021 Category: Dermatology Authors: W H Chan R Srivastava N Damaraju H Do G Burnett J MacFarlane S M Xie J K Chen G Honari K Y Sarin Source Type: research

Development of a shared decision-making tool in vitiligo: an international study
CONCLUSION: We have developed a tool for shared decision making in non-segmental vitiligo which we translated and cross-culturally validated in a US vitiligo patient population to ensure its generalizability.PMID:33830502 | DOI:10.1111/bjd.20137 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 8, 2021 Category: Dermatology Authors: J Shourick M Ahmed J Seneschal T Passeron N Andreux A Qureshi E Y Chow P A Natella J Harris V-T Tran K Ezzedine Source Type: research

The risk of malignancy in secukinumab-treated psoriasis, psoriatic arthritis and ankylosing spondylitis patients: analysis of up to five-year clinical trial and post-marketing surveillance data
CONCLUSIONS: In this large safety analysis, the risk of malignancy was low for up to five years of secukinumab treatment. These data support the long-term us of secukinumab in these indications.PMID:33829482 | DOI:10.1111/bjd.20136 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 8, 2021 Category: Dermatology Authors: M Lebwohl A Deodhar C E M Griffiths M A Menter D Poddubnyy W Bao V Jehl K Marfo P Primatesta A Shete V Trivedi P J Mease Source Type: research

Cutaneous squamous cell carcinoma is associated with Lynch syndrome; widening the spectrum of Lynch syndrome associated tumours
Br J Dermatol. 2021 Apr 7. doi: 10.1111/bjd.20139. Online ahead of print.ABSTRACTDear Editor, Lynch syndrome (LS) is caused by a germline mutation in one of the mismatch repair (MMR) genes. Individuals with LS have an increased risk of developing colorectal and many other tumours including skin tumours.1 Sebaceous neoplasms and keratoacanthomas are skin tumours associated with LS, also known as Muir-Torre syndrome. For cutaneous squamous cell carcinoma (SCC), an association with LS has been suggested.PMID:33829484 | DOI:10.1111/bjd.20139 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 8, 2021 Category: Dermatology Authors: B L M Ykema F Adan M B Crijns F E Bleeker E Dekker M W Bekkenk P Snaebjornsson M E van Leerdam Source Type: research

Novel light-dependent and light-independent functions of opsin 5
Br J Dermatol. 2021 Apr 7. doi: 10.1111/bjd.20052. Online ahead of print.NO ABSTRACTPMID:33829486 | DOI:10.1111/bjd.20052 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 8, 2021 Category: Dermatology Authors: L V M de Assis A M L Castrucci Source Type: research

Defining Trajectories of Response in Psoriasis Patients Treated with Biologic Therapies
CONCLUSION: These subgroups, defined by change in disease over time, may be indicative of distinct endotypes driven by different biological mechanisms and may help inform the management of patients with psoriasis. Future work will aim to further delineate these mechanisms by extensively characterising the subgroups with additional molecular and pharmacological data.PMID:33829489 | DOI:10.1111/bjd.20140 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 8, 2021 Category: Dermatology Authors: N Geifman N Azadbakht J Zeng T Wilkinson N Dand I Buchan D Stocken P Di Meglio R B Warren J N Barker N J Reynolds M R Barnes C H Smith C E M Griffiths N Peek BADBIR Study Group, on behalf of the PSORT Consortium Source Type: research

Efficacy of S-1 plus docetaxel in the treatment of metastatic extramammary Paget's disease: a multicentre retrospective study
Br J Dermatol. 2021 Apr 8. doi: 10.1111/bjd.20135. Online ahead of print.ABSTRACTMetastatic extramammary Paget's disease (EMPD) is an intractable condition that is refractory to conventional treatments and the outcomes remain unsatisfactory1 . Establishing an effective regimen with higher response rates and long-term efficacy is required.PMID:33829494 | DOI:10.1111/bjd.20135 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 8, 2021 Category: Dermatology Authors: S Matsushita K Fujii I Kajihara M Aoki K Yamamura K Tada T Kanekura J Aoi S Fukushima Source Type: research

Dupilumab-associated arthralgia: an observational retrospective study in VigiBase ®
Br J Dermatol. 2021 Apr 7. doi: 10.1111/bjd.20138. Online ahead of print.ABSTRACTDear Editor, Dupilumab is a human monoclonal antibody that blocks the shared receptor unit for interleukin (IL)-4 and IL-13, and is approved in several indications, including moderate-to-severe atopic dermatitis (AD). According to a recent meta-analysis dupilumab treatment versus placebo resulted in a significant increase in the number of patients who achieved Eczema Area and Severity Index-75 (Rate-Ratio 3.09; 95% CI 2.45-3.89) in different ethnical populations.PMID:33829495 | DOI:10.1111/bjd.20138 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 8, 2021 Category: Dermatology Authors: B Chr étien C Dolladille J Alexandre S Fedrizzi V Lelong-Boulouard J C Lambert E Ezine Source Type: research