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Comorbidities of pyoderma gangrenosum: a retrospective multicentric analysis of 126 patients.
This article is protected by copyright. All rights reserved. PMID: 29453858 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 17, 2018 Category: Dermatology Authors: Gillard M, Anuset D, Maillard H, Senet P, Cuny JF, Mahe E, Sin C, Dessiner F, Goujon E, Journet-Tollhupp J, Debure C, Dabouz F, Develter T, Bernard P, Lok C, Modiano P, et le Groupe d'Angiodermatologie de la SFD Tags: Br J Dermatol Source Type: research

"It's a traumatic illness, traumatic to witness." A qualitative study of the experiences of bereaved family caregivers of patients with cutaneous T-cell lymphoma.
CONCLUSIONS: Family caregivers should be considered part of the wider healthcare team, acknowledging their multiple roles and the challenges they encounter in looking after their relative with CTCL as the disease progresses. Their experiences highlight the importance of organisational flexibility and of good communication between health care providers in advanced CTCL. This article is protected by copyright. All rights reserved. PMID: 29451670 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 16, 2018 Category: Dermatology Authors: Orlowska D, Selman LE, Beynon T, Radcliffe E, Whittaker S, Child F, Harding R Tags: Br J Dermatol Source Type: research

The Validity of the Diagnostic Code for Pyoderma Gangrenosum in an Electronic Database.
This article is protected by copyright. All rights reserved. PMID: 29451671 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 16, 2018 Category: Dermatology Authors: Lockwood SJ, Li DG, Butler D, Tsiaras W, Joyce C, Mostaghimi A Tags: Br J Dermatol Source Type: research

Successful therapy of Pyoderma gangrenosum with a JAK2 inhibitor.
This article is protected by copyright. All rights reserved. PMID: 29451690 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 16, 2018 Category: Dermatology Authors: Nasifoglu S, Heinrich B, Welzel J Tags: Br J Dermatol Source Type: research

Aquagenic Wrinkling of the Palms in Patients with Cystic Fibrosis.
This article is protected by copyright. All rights reserved. PMID: 29451691 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 16, 2018 Category: Dermatology Authors: Kaiser H, Brustad N, Pressler T, Bygum A Tags: Br J Dermatol Source Type: research

Acute psychosocial stress downregulates N-Methyl-d-aspartate receptors (NMDAR) in healthy human skin.
This article is protected by copyright. All rights reserved. PMID: 29451693 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 16, 2018 Category: Dermatology Authors: Hunter HJA, Morsman E, Mellody KT, Ogden SK, Zeef LAH, Hayes A, Griffiths CEM, Kleyn CE Tags: Br J Dermatol Source Type: research

Children with Facial Morphea Managing Everyday Life: A Qualitative Study.
CONCLUSION: Understanding what it is like to live with facial morphea from the perspectives of children and parents is important for devising ways to support children with facial morphea to achieve a better quality of life. Health care providers can help families access resources to manage anxiety, deal with bullying and construct adequate explanations of facial morphea, as well as providing opportunities for peer support. This article is protected by copyright. All rights reserved. PMID: 29451694 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 16, 2018 Category: Dermatology Authors: Stasiulis E, Gladstone B, Boydell K, O'Brien C, Pope E, Laxer R Tags: Br J Dermatol Source Type: research

Optimizing case reports and case series: guidance on how to improve quality.
This article reviews their characteristics, aims and limitations. It provides information on how to increase the validity of the bedside decision-making process that these studies report, using tools such as validated outcomes and split body or n-of-1 trials. A section describing tools to improve writing of case reports and case series provides suggestions for detailed reporting and good evaluation of novelty, validity and relevance. It includes general and British Journal of Dermatology specific guidance. This article is protected by copyright. All rights reserved. PMID: 29451697 [PubMed - as supplied by publisher] (...
Source: The British Journal of Dermatology - February 16, 2018 Category: Dermatology Authors: Garcia-Doval I, Albrecht J, Flohr C, Batchelor J, Ingram JR, European Dermato-Epidemiology Network (EDEN) Tags: Br J Dermatol Source Type: research

Dermatology Training Across the Globe, Part II: A summary of the literature.
This article is protected by copyright. All rights reserved. PMID: 29451700 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 16, 2018 Category: Dermatology Authors: Ashack KA, Burton KA, Barber C, St Claire K, Mounessa J, Dunnick CA, Norris DA, Dellavalle RP Tags: Br J Dermatol Source Type: research

Core outcome sets in dermatology: report from the second meeting of the International Cochrane Skin Group Core Outcome Set Initiative.
Core Outcome Set Initiative (CSG-COUSIN) group Abstract Results of clinical trials are the most important information source for generating external clinical evidence. The use of different outcomes across trials, which investigate similar interventions for similar patient groups, significantly limits the interpretation, comparability and clinical application of trial results. Core outcome sets (COSs) aim to overcome this limitation. A COS is an agreed standardized collection of outcomes that should be measured and reported in all clinical trials for a specific clinical condition. The Core Outcome Set Initiative w...
Source: The British Journal of Dermatology - February 14, 2018 Category: Dermatology Authors: Kottner J, Jacobi L, Hahnel E, Alam M, Balzer K, Beeckman D, Busard C, Chalmers J, Deckert S, Eleftheriadou V, Furlan K, Horbach SER, Kirkham J, Nast A, Spuls P, Thiboutot D, Thorlacius L, Weller K, Williams HC, Schmitt J, International Cochrane Skin Grou Tags: Br J Dermatol Source Type: research

Clinician surveys - time to make better use of this valuable resource for dermatologists.
This article is protected by copyright. All rights reserved. PMID: 29444336 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 14, 2018 Category: Dermatology Authors: Wernham AGH, Ingram JR, Matin RN Tags: Br J Dermatol Source Type: research

Phacomatosis pigmentokeratotica: a case of HRAS mosaicism causing rhabdomyosarcoma.
This article is protected by copyright. All rights reserved. PMID: 29430633 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 12, 2018 Category: Dermatology Authors: Prieto-Barrios M, Llamas-Martin R, Velasco-Tamariz V, Calleja-Algarra A, Ruano Y, Ortiz-Romero PL, Rodriguez-Peralto JL Tags: Br J Dermatol Source Type: research

A randomized, multi-national, non-inferiority, phase III trial to evaluate the safety and efficacy of BF-200 ALA gel versus MAL cream in the treatment of non-aggressive basal cell carcinoma with photodynamic therapy (PDT).
, Gupta G, Hübinger F, Ziabreva I, Schmitz B, Gertzmann A, Lübbert H, Szeimies RM Abstract BACKGROUND: Basal cell carcinoma (BCC) represents the most common non-melanoma skin cancer worldwide affecting mainly adult, fair-skinned individuals. The WHO distinguishes aggressive and non-aggressive forms of which prototypical variants of the latter are primary nodular and superficial BCC. OBJECTIVES: To demonstrate non-inferiority of BF-200 ALA (a nanoemulsion gel containing 5-aminolaevulinic acid) compared to MAL (a cream containing methyl-aminolevulinate) in the treatment of non-aggressive BCC with phot...
Source: The British Journal of Dermatology - February 12, 2018 Category: Dermatology Authors: Morton CA, Dominicus R, Radny P, Dirschka T, Hauschild A, Reinhold U, Aschoff R, Ulrich M, Keohane S, Ekanayake-Bohlig S, Ibbotson S, Ostendorf R, Berking C, Gröne D, Schulze HJ, Ockenfels HM, Jasnoch V, Kurzen H, Sebastian M, Stege H, Staubach-Renz P, G Tags: Br J Dermatol Source Type: research

Pilocarpine and Artificial Saliva for the Treatment of Xerostomia and Xerophthalmia of Sj ögren's Syndrome: A double blind control trial.
Pilocarpine and Artificial Saliva for the Treatment of Xerostomia and Xerophthalmia of Sjögren's Syndrome: A double blind control trial. Br J Dermatol. 2018 Feb 12;: Authors: Cifuentes M, Del Barrio-Díaz P, Vera-Kellet C Abstract BACKGROUND: Sjögren's Syndrome (SS) is associated with xerostomia and xerophthalmia. Pilocarpine stimulates the secretion of saliva. OBJECTIVES: Investigate and compare the efficacy of pilocarpine and artificial saliva as symptomatic treatments for xerostomia and xerophthalmia in patients with SS. PATIENTS AND METHODS: A double-blind, randomized, co...
Source: The British Journal of Dermatology - February 12, 2018 Category: Dermatology Authors: Cifuentes M, Del Barrio-Díaz P, Vera-Kellet C Tags: Br J Dermatol Source Type: research

A Review of Clinical Trial Registry Use in Dermatology Systematic Reviews.
This article is protected by copyright. All rights reserved. PMID: 29432649 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 12, 2018 Category: Dermatology Authors: Combs T, Atakpo P, Vassar M Tags: Br J Dermatol Source Type: research

The synergistic activities of the combination of TNF- α, IL-17A, and IFN-γ in epidermal keratinocytes.
This article is protected by copyright. All rights reserved. PMID: 29432653 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 12, 2018 Category: Dermatology Authors: Morizane S, Nomura H, Tachibana K, Nakagawa Y, Iwatsuki K Tags: Br J Dermatol Source Type: research

Eccrine sweat glands associate with the human hair follicle within a defined compartment of dermal white adipose tissue.
CONCLUSIONS: We propose a model of functional human skin anatomy in which ESGs are closely associated with the PSU and the dWAT to form a common homeostatic tissue environment, which may best be encapsulated in the term adnexal skin unit (aSU). The challenge now is to dissect how each component of this superstructure of human skin functionally cooperates with and influences the other under physiological conditions, during regeneration/repair and in selected skin diseases. This article is protected by copyright. All rights reserved. PMID: 29432654 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 12, 2018 Category: Dermatology Authors: Poblet E, Jimenez-Acosta F, Escario-Travesedo E, Hardman JA, Hernández-Hernández I, Agudo-Mena JL, Cabrera-Galvan JJ, Nicu C, Paus R Tags: Br J Dermatol Source Type: research

Effects of treatment for psoriasis on circulating levels of leptin, adiponectin and resistin: a systematic review and meta-analysis.
Abstract BACKGROUND: Metabolic syndrome, a risk factor of cardiovascular disease, is more common in psoriatic patients compared to general population. Circulating adipokine concentrations are altered in psoriatic patients and are suggested to represent the pathophysiologic link between psoriatic lesions and metabolic alterations. OBJECTIVES: To systematically review the literature for studies that investigated possible differences in the circulating levels of leptin, adiponectin or resistin in psoriatic patients before and after any treatment intervention and meta-analyze the best evidence available. MET...
Source: The British Journal of Dermatology - February 12, 2018 Category: Dermatology Authors: Kyriakou A, Patsatsi A, Sotiriadis D, Goulis DG Tags: Br J Dermatol Source Type: research

Onychoscopy of trachyonychia: An analysis of 30 patients and comparison with onychomycosis.
This article is protected by copyright. All rights reserved. PMID: 29417570 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 8, 2018 Category: Dermatology Authors: Jo G, Park JS, Yu DA, Ohn J, Sheu SL, Mun JH Tags: Br J Dermatol Source Type: research

Risk of depression among patients with acne in the U.K.: a population-based cohort study.
PMID: 29411352 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 7, 2018 Category: Dermatology Authors: Vallerand IA, Lewinson RT, Parsons LM, Lowerison MW, Frolkis AD, Kaplan GG, Barnabe C, Bulloch AGM, Patten SB Tags: Br J Dermatol Source Type: research

Wide skin markings pattern - melanoma descriptor or patient-related factor?: reply from authors.
This article is protected by copyright. All rights reserved. PMID: 29411876 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 7, 2018 Category: Dermatology Authors: Longo C, Lallas A, Kyrgidis A, Bassoli S, Moscarella E, Pellacani G, Argenziano G Tags: Br J Dermatol Source Type: research

Baseline neutrophil to lymphocyte ratio combined with serum LDH level associated with outcome of nivolumab immunotherapy in a Japanese advanced melanoma population.
This article is protected by copyright. All rights reserved. PMID: 29405254 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 6, 2018 Category: Dermatology Authors: Fujisawa Y, Yoshino K, Otsuka A, Funakoshi T, Fujimura T, Yamamoto Y, Hata H, Tanaka R, Yamaguchi K, Nonomura Y, Hirai I, Furudate S, Okuhira H, Imafuku K, Aoki M, Matsushita S Tags: Br J Dermatol Source Type: research

Efficacy and safety of continuous every 2-week dosing of ixekizumab over 52 weeks in patients with moderate-to-severe plaque psoriasis in a randomized phase 3 trial (IXORA-P).
CONCLUSIONS: Ixekizumab Q2W had higher efficacy at Week 52 compared to Q4W, with no increase in safety events. This article is protected by copyright. All rights reserved. PMID: 29405255 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 6, 2018 Category: Dermatology Authors: Langley RG, Papp K, Gooderham M, Zhang L, Mallinckrodt C, Agada N, Blauvelt A, Foley P, Polzer P, IXORA-P investigators Tags: Br J Dermatol Source Type: research

Complement activation in hidradenitis suppurativa: a new pathway of pathogenesis?
CONCLUSIONS: Systemic complement activation occurs in HS and may be used as a surrogate biomarker of HS. C5a stimulates over-production of TNFα and may be a future therapeutic target. This article is protected by copyright. All rights reserved. PMID: 29405257 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 6, 2018 Category: Dermatology Authors: Kanni T, Zenker O, Habel M, Riedemann N, Giamarellos-Bourboulis EJ Tags: Br J Dermatol Source Type: research

Application of in vivo reflectance confocal microscopy (RCM) and ex vivo fluorescence confocal microscopy (FCM) in most common subtypes of Basal Cell Carcinoma and correlation with histopathology.
This article is protected by copyright. All rights reserved. PMID: 29405259 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 6, 2018 Category: Dermatology Authors: Villarreal-Martinez A, Bennàssar A, Gonzalez S, Malvehy J, Puig S Tags: Br J Dermatol Source Type: research

Hyaluronan metabolism enhanced during epidermal differentiation is suppressed by vitamin C.
CONCLUSIONS: Epidermal stratification and maturation is associated with enhanced hyaluronan turnover, and release of large amounts of hyaluronan fragments. The high turnover is suppressed by vitamin C, which is suggested to enhance normal epidermal differentiation in part through its effect on hyaluronan. This article is protected by copyright. All rights reserved. PMID: 29405260 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 6, 2018 Category: Dermatology Authors: Hämäläinen L, Kärkkäinen E, Takabe P, Rauhala L, Bart G, Kärnä R, Pasonen-Seppänen S, Oikari S, Tammi MI, Tammi RH Tags: Br J Dermatol Source Type: research

Wide skin markings pattern - melanoma descriptor or patient-related factor?
This article is protected by copyright. All rights reserved. PMID: 29405262 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 6, 2018 Category: Dermatology Authors: Rishpon A, Marchetti M, Marghoob A Tags: Br J Dermatol Source Type: research

Oral retinoids and depression.
This article is protected by copyright. All rights reserved. PMID: 29399783 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 5, 2018 Category: Dermatology Authors: Lehloenya R, Jessop S Tags: Br J Dermatol Source Type: research

Subcutaneous methotrexate in patients with moderate to severe psoriasis: a critical appraisal.
CONCLUSIONS: Warren et al conclude that the 52-week risk-benefit profile of subcutaneous methotrexate is favourable in patients with psoriasis. This article is protected by copyright. All rights reserved. PMID: 29399784 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 5, 2018 Category: Dermatology Authors: Tsakok T, Jabbar-Lopez ZK, Smith CH Tags: Br J Dermatol Source Type: research

Oral retinoids and depression: reply from the authors.
This article is protected by copyright. All rights reserved. PMID: 29405256 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 5, 2018 Category: Dermatology Authors: Le Moigne M, Fournier JP, Victorri-Vigneau C, Dréno B Tags: Br J Dermatol Source Type: research

The PARACELSUS score: A novel diagnostic tool for pyoderma gangrenosum.
CONCLUSION: The PARACELSUS score represents a novel, easily implementable, effective and sensitive diagnostic tool for PG. This article is protected by copyright. All rights reserved. PMID: 29388188 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 1, 2018 Category: Dermatology Authors: Jockenhöfer F, Wollina U, Salva KA, Benson S, Dissemond J Tags: Br J Dermatol Source Type: research

Inequalities in zoster disease burden: a population-based cohort study to identify social determinants using linked data from the UK Clinical Practice Research Datalink.
CONCLUSIONS: The burden of zoster was higher in specific socio-demographic groups. Further study is needed to ascertain whether these individuals are attending for zoster vaccination. This article is protected by copyright. All rights reserved. PMID: 29388189 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 1, 2018 Category: Dermatology Authors: Jain A, van Hoek AJ, Walker JL, Forbes HJ, Langan SM, Root A, Smeeth L, Thomas SL Tags: Br J Dermatol Source Type: research

Sirolimus for treatment of Kaposiform hemangioendothelioma with Kasabach-Merritt phenomenon: A retrospective cohort study.
This article is protected by copyright. All rights reserved. PMID: 29388191 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 1, 2018 Category: Dermatology Authors: Zhang G, Chen H, Gao Y, Liu Y, Wang J, Liu XY Tags: Br J Dermatol Source Type: research

Acne and hidradenitis suppurativa.
Abstract Acne and hidradenitis suppurativa (HS) both centre on hair follicles. They often occur together as part of the acne tetrad, but are found in distinct localizations. Acne is primarily defined by the presence of comedones and inflammatory lesions. However, in HS the intertriginous localization and chronicity play equally important roles for the diagnosis to the inflammatory lesions. Genetics, bacteria, environmental factors and innate inflammation have all been found to play a role in acne and/or HS. Surprisingly, there is little overlap between the findings so far. The genetics of acne and HS are distinct,...
Source: The British Journal of Dermatology - January 30, 2018 Category: Dermatology Authors: Pink A, Anzengruber F, Navarini AA Tags: Br J Dermatol Source Type: research

Retrospective study: Rapamycin or rapalog 0.1% cream for facial angiofibromas in Tuberous Sclerosis Complex: Evaluation of treatment effectiveness and cost.
This article is protected by copyright. All rights reserved. PMID: 29380350 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 30, 2018 Category: Dermatology Authors: Norrenberg S, Masconi M, Karamanou M, Meylan P, Golaz R, Christen-Zaech S Tags: Br J Dermatol Source Type: research

Initial validation of the Burden of Disease in Atopic Eczema instrument, a quality of life measure for adult atopic dermatitis.
This article is protected by copyright. All rights reserved. PMID: 29380862 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 30, 2018 Category: Dermatology Authors: Wang R, Dunlap RR, Darwish MA, Simpson EL, Hanifin JM, Qureshi AA, Du L, Drucker AM Tags: Br J Dermatol Source Type: research

No difference in UVB-induced changes in antigen-presenting cells and in cytokines between subjects with and without loss-of-function mutations in FLG.
This article is protected by copyright. All rights reserved. PMID: 29377073 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 29, 2018 Category: Dermatology Authors: Simonsen S, Bonefeld CM, Thyssen JP, Christiansen AT, Geisler C, Skov L Tags: Br J Dermatol Source Type: research

Filaggrin gene mutations may influence the persistence of food allergies in Japanese primary school children.
This article is protected by copyright. All rights reserved. PMID: 29369340 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 25, 2018 Category: Dermatology Authors: Kono M, Akiyama M, Inoue Y, Nomura T, Hata A, Okamoto Y, Takeichi T, Muro Y, McLean WHI, Shimizu H, Sugiura K, Suzuki Y, Shimojo N Tags: Br J Dermatol Source Type: research

Terbinafine-induced liver injury may be asymptomatic: need for regular monitoring: reply from the authors.
PMID: 29370453 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 25, 2018 Category: Dermatology Authors: Albrecht J, Kramer ON Tags: Br J Dermatol Source Type: research

Pulsed-dye laser therapy for carcinoma in situ of the penis.
This article is protected by copyright. All rights reserved. PMID: 29368336 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 24, 2018 Category: Dermatology Authors: Niederkorn A, Sadoghi B, Komericki P Tags: Br J Dermatol Source Type: research

A profile of Propionibacterium acnes resistance and sensitivity at a tertiary dermatological centre in Singapore.
This article is protected by copyright. All rights reserved. PMID: 29368337 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 24, 2018 Category: Dermatology Authors: Liau MM, Yang SS, Long V, Lee SH, Toh M, Teo J, Tan C, Aw D Tags: Br J Dermatol Source Type: research

Omalizumab updosing allows disease activity control in refractory patients with chronic spontaneous urticaria.
This article is protected by copyright. All rights reserved. PMID: 29368377 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 24, 2018 Category: Dermatology Authors: Curto-Barredo L, Spertino J, Figueras-Nart I, Expósito-Serrano V, Guilabert A, Melé-Ninot G, Cubiró X, Bonfill-Ortí M, Garcias-Ladaria J, Villar M, García-Navarro X, Bielsa-Marsol I, Vilavella M, Aparicio G, Baliu-Piqué C, Álvarez A, Lamas-Domenech Tags: Br J Dermatol Source Type: research

Dermoscopic features of pilar leiomyomas.
This article is protected by copyright. All rights reserved. PMID: 29368390 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 24, 2018 Category: Dermatology Authors: Behera B, Vinupriya S, Kumari R, Thappa DM, Gochhait D, Srinivas B, Toi P Tags: Br J Dermatol Source Type: research

A prospective 52-week randomised controlled trial of patient-initiated care consultations for patients with psoriasis.
CONCLUSION: PICC offers additional clinical benefits compared to routine care, making patients less dependent on clinical visits. The intervention adds no harm to monitoring systemic treatment and patients report high quality of life and satisfaction with healthcare. This article is protected by copyright. All rights reserved. PMID: 29363093 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 24, 2018 Category: Dermatology Authors: Khoury LR, Møller T, Zachariae C, Skov L Tags: Br J Dermatol Source Type: research

How should minimally important change (MIC) scores for the Patient Oriented Eczema Measure (POEM) be interpreted? A validation using varied methods.
CONCLUSIONS: We recommend the following thresholds are used to interpret changes in POEM scores: ≤ 2, unlikely to be a change beyond measurement error; 2.1 to 2.9, a small change detected that is likely to be beyond measurement error but may not be clinically important; 3 to 3.9, probably a clinically important change; 4+, very likely to be a clinically important change. This article is protected by copyright. All rights reserved. PMID: 29355894 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 21, 2018 Category: Dermatology Authors: Howells L, Ratib S, Chalmers JR, Bradshaw L, Thomas KS, CLOTHES trial team Tags: Br J Dermatol Source Type: research

Differential effects of secukinumab vs. ustekinumab for treatment of psoriasis on quality of life, work productivity and activity impairment: a structural equation modelling analysis.
CONCLUSION: The results underscore the important role of both PASI response and reduction in symptoms on improvements in health-related quality of life and work and daily activity in favour of secukinumab vs. ustekinumab. This article is protected by copyright. All rights reserved. PMID: 29355896 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 21, 2018 Category: Dermatology Authors: Stull DE, Griffiths CEM, Gilloteau I, Zhao Y, Guana A, Finlay AY, Sherif B, Houghton K, Puig L Tags: Br J Dermatol Source Type: research

In vivo dermoscopic and confocal microscopy multi-step algorithm to detect in situ melanomas.
CONCLUSIONS: An easy and reproducible multi-step algorithm for MIS detection is suggested, that can be routinely used in tertiary centres. This article is protected by copyright. All rights reserved. PMID: 29355898 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 21, 2018 Category: Dermatology Authors: Borsari S, Pampena R, Benati E, Bombonato C, Athanassios K, Moscarella E, Lallas A, Argenziano G, Pellacani G, Longo C Tags: Br J Dermatol Source Type: research

A multi-centre, open, investigator initiated phase IV clinical trial to evaluate the efficacy and safety of ingenol mebutate gel, 0.015% on the face and scalp, and 0.05% on the trunk and extremities, in Korean patients with actinic keratosis (PERFECT).
CONCLUSIONS: Ingenol mebutate is effective for the treatment of AK in Asians, with tolerable safety profiles. This article is protected by copyright. All rights reserved. PMID: 29355904 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 20, 2018 Category: Dermatology Authors: Kim YC, Yang JY, Yoon JS, Jo SJ, Ahn HH, Song KH, Lee DY, Chung KY, Won YH, Kim IH Tags: Br J Dermatol Source Type: research

Effects of neuroimmune axis modulation by aprepitant on anti-pruritic and global disease severity in patients with cutaneous T-cell lymphoma.
This article is protected by copyright. All rights reserved. PMID: 29352478 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 20, 2018 Category: Dermatology Authors: Kwatra SG, Boozalis E, Kwatra MM Tags: Br J Dermatol Source Type: research

Aprepitant did not modify global disease activity in cutaneous T cell lymphomas.
This article is protected by copyright. All rights reserved. PMID: 29352481 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 20, 2018 Category: Dermatology Authors: Maroñas-Jiménez L, Ortiz-Romero PL Tags: Br J Dermatol Source Type: research