Comorbidities in people with psoriasis
Br J Dermatol. 2024 Feb 16;190(3):e31. doi: 10.1093/bjd/ljae026.NO ABSTRACTPMID:38366833 | DOI:10.1093/bjd/ljae026 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 17, 2024 Category: Dermatology Source Type: research
Safety of combination therapy for psoriasis: findings from the BIOBADADERM registry
Br J Dermatol. 2024 Feb 16;190(3):e30. doi: 10.1093/bjd/ljae025.NO ABSTRACTPMID:38366834 | DOI:10.1093/bjd/ljae025 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 17, 2024 Category: Dermatology Source Type: research
Macrophages dampen skin inflammation after stem cell transplantation
Br J Dermatol. 2024 Feb 16;190(3):e35. doi: 10.1093/bjd/ljae030.NO ABSTRACTPMID:38366835 | DOI:10.1093/bjd/ljae030 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 17, 2024 Category: Dermatology Source Type: research
Alopecia areata and comorbidities associated with it in Germany
Br J Dermatol. 2024 Feb 16;190(3):e32. doi: 10.1093/bjd/ljae027.NO ABSTRACTPMID:38366836 | DOI:10.1093/bjd/ljae027 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 17, 2024 Category: Dermatology Source Type: research
Cumulative methotrexate dose is not associated with liver fibrosis in patients with a history of moderate to severe psoriasis
CONCLUSION: This study confirms a high prevalence of significant LF in patients with psoriasis. Cumulative methotrexate dose was not associated with LF. Patients with BMI ≥28 kg/m2, metabolic syndrome and diabetes are at higher risk for LF. These risk factor may help to identify when a more detailed liver health assessment is needed.PMID:38366967 | DOI:10.1093/bjd/ljae069 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 17, 2024 Category: Dermatology Authors: Parastoo Babakinejad Rebecca Lapsley Lara Forster Stuart McPherson Mark S Pearce Nick J Reynolds Emma Slack Sophie C Weatherhead Philip J Hampton Source Type: research
Acceptability of 'as needed' biologic therapy in psoriasis: insights from a multi-stakeholder mixed methods study
CONCLUSION: These data indicate that 'as needed' biologic therapy in psoriasis is acceptable for both patients and clinicians. Formal assessment of clinical effectiveness and cost effectiveness is warranted, to enable the real-world potential of this approach to be realised.PMID:38366988 | DOI:10.1093/bjd/ljae068 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 17, 2024 Category: Dermatology Authors: David Gleeson Maneeha Naveed Lucy Moorhead Helen McAteer Georgia Sewell Arlene McGuire John Weinman Jonathan N W N Barker Sam Norton Sarah C E Chapman Catherine H Smith Satveer K Mahil Source Type: research
Benralizumab does not elicit therapeutic effect in patients with chronic spontaneous urticaria: results from the phase 2b multinational, randomised, double-blind, placebo-controlled ARROYO trial
CONCLUSIONS: Although benralizumab resulted in near-complete depletion of blood eosinophils, there was no clinical benefit over placebo.PMID:38367194 | DOI:10.1093/bjd/ljae067 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 17, 2024 Category: Dermatology Authors: Sabine Altrichter Ana Maria Gim énez-Arnau Jonathan A Bernstein Martin Metz Lila Bahadori Maria Bergquist Laura Brooks Calvin N Ho Priya Jain Pradeep B Lukka Eva Rodriguez-Su árez Claire Walton Catherine J Datto ARROYO Study Investigators Source Type: research
Feasibility of Daily Pain Measurement Using Text Messages in Hidradenitis Suppurativa Clinical Trials; Data from THESEUS Study
Br J Dermatol. 2024 Feb 14:ljae057. doi: 10.1093/bjd/ljae057. Online ahead of print.NO ABSTRACTPMID:38365908 | DOI:10.1093/bjd/ljae057 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 16, 2024 Category: Dermatology Authors: Samar B Hasan Janine Bates Rebecca Cannings-John Fiona Collier Judith Evans Angela Gibbons Ceri Harris Laura Howells Kerenza Hood Rachel Howes Paul Leighton Muhammad Riaz Jeremy Rodrigues Helen Stanton Kim S Thomas Emma Thomas-Jones John R Ingram Source Type: research
Histamine- and Pruritogen-induced Itch is Inhibited by a TRPM8 Agonist in Humans: A Randomized, Vehicle-controlled Trial
CONCLUSIONS: The study demonstrates that the specific TRPM8 agonist gel effectively suppresses human skin itch induced by various pruritogens. These versatile actions suggest cooling agents may be promising treatments for multiple forms of itch stimuli.PMID:38345103 | DOI:10.1093/bjd/ljae054 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 12, 2024 Category: Dermatology Authors: Soyeon Lee Edward T Wei Tudor Selescu Alexandru Babes Jinseo Park Jincheol Kim Boyoung Chung Chunwook Park Hyeone Kim Source Type: research
Prurigo Nodularis: New insights into pathogenesis and novel therapeutics
Br J Dermatol. 2024 Feb 12:ljae052. doi: 10.1093/bjd/ljae052. Online ahead of print.ABSTRACTPrurigo nodularis (PN) is an inflammatory skin condition characterized by intensely pruritic nodules on the skin. PN patients suffer from an intractable itch-scratch cycle leading to impaired sleep, psychosocial distress, and a significant disruption in quality of life. The pathogenesis of PN is associated with immune and neural dysregulation, mediated by inflammatory cytokines (such as IL-4, -13, -17, -22, and -31) and neuropeptides (such as substance P and calcitonin gene-related peptide). There is a role for type 2 inflammation i...
Source: The British Journal of Dermatology - February 12, 2024 Category: Dermatology Authors: Viviane Liao Hannah L Cornman Emily Ma Shawn G Kwatra Source Type: research
Histamine- and Pruritogen-induced Itch is Inhibited by a TRPM8 Agonist in Humans: A Randomized, Vehicle-controlled Trial
CONCLUSIONS: The study demonstrates that the specific TRPM8 agonist gel effectively suppresses human skin itch induced by various pruritogens. These versatile actions suggest cooling agents may be promising treatments for multiple forms of itch stimuli.PMID:38345103 | DOI:10.1093/bjd/ljae054 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 12, 2024 Category: Dermatology Authors: Soyeon Lee Edward T Wei Tudor Selescu Alexandru Babes Jinseo Park Jincheol Kim Boyoung Chung Chunwook Park Hyeone Kim Source Type: research
Prurigo Nodularis: New insights into pathogenesis and novel therapeutics
Br J Dermatol. 2024 Feb 12:ljae052. doi: 10.1093/bjd/ljae052. Online ahead of print.ABSTRACTPrurigo nodularis (PN) is an inflammatory skin condition characterized by intensely pruritic nodules on the skin. PN patients suffer from an intractable itch-scratch cycle leading to impaired sleep, psychosocial distress, and a significant disruption in quality of life. The pathogenesis of PN is associated with immune and neural dysregulation, mediated by inflammatory cytokines (such as IL-4, -13, -17, -22, and -31) and neuropeptides (such as substance P and calcitonin gene-related peptide). There is a role for type 2 inflammation i...
Source: The British Journal of Dermatology - February 12, 2024 Category: Dermatology Authors: Viviane Liao Hannah L Cornman Emily Ma Shawn G Kwatra Source Type: research
Global burden of vaccine-associated alopecia, 1979-2023: a comprehensive analysis of the international pharmacovigilance database
Br J Dermatol. 2024 Feb 9:ljae055. doi: 10.1093/bjd/ljae055. Online ahead of print.NO ABSTRACTPMID:38332614 | DOI:10.1093/bjd/ljae055 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 9, 2024 Category: Dermatology Authors: Seoyeon Kyung Selin Woo Minji Kim Hayeon Lee Jiseung Kang Masoud Rahmati Dong Keon Yon Source Type: research
Global, Regional, and National Epidemiology of Alopecia Areata: A Systematic Review and Modelling Study
CONCLUSIONS: In this study, 48% of the total Global Burden of Disease regions had insufficient data reporting the prevalence or incidence of AA. Further studies are needed to provide epidemiological information on middle- and low-income countries. Our study can serve as a crucial reference in terms of healthcare policy decisions.PMID:38332643 | DOI:10.1093/bjd/ljae058 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 9, 2024 Category: Dermatology Authors: Jae Joon Jeon Seung-Won Jung You Hyun Kim Rosa Parisi Ju Yeong Lee Myung Ha Kim Won-Soo Lee Solam Lee Source Type: research
Ethical Considerations for Artificial Intelligence in Dermatology: A Scoping Review
Br J Dermatol. 2024 Feb 8:ljae040. doi: 10.1093/bjd/ljae040. Online ahead of print.ABSTRACTThe field of dermatology is experiencing the rapid deployment of artificial intelligence (AI), from mobile applications for skin cancer detection to large language models like ChatGPT that can answer generalist or specialist questions about skin diagnoses. With these new applications, ethical concerns have emerged. In this scoping review, we aim to identify the applications of AI to the field of dermatology and to understand their ethical implications. We utilized a multifaceted search approach, searching PubMed, Medline, Cochrane, a...
Source: The British Journal of Dermatology - February 8, 2024 Category: Dermatology Authors: Emily R Gordon Megan H Trager Despina Kontos Chunhua Weng Larisa J Geskin Lydia S Dugdale Faramarz H Samie Source Type: research
