Herpetiform Pemphigus with Characteristic Transmission Electron Microscopic Findings of Various-sized Ballooning Vacuoles in Keratinocytes without Acantholysis.
This article is protected by copyright. All rights reserved. PMID: 29573413 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 24, 2018 Category: Dermatology Authors: Ishiura N, Tamura-Nakano M, Okochi H, Tateishi C, Maki M, Shimoda Y, Ishii N, Hashimoto T, Tamaki T Tags: Br J Dermatol Source Type: research

Actinic keratosis area severity index (AKASI): Reproducibility study and comparison with total lesion count.
This article is protected by copyright. All rights reserved. PMID: 29572818 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 23, 2018 Category: Dermatology Authors: Pellacani G, Gupta G, Micali G, Malvehy J, Stratigos AJ, Casari A, Cheseter J, Kaleci S, Dirschka T Tags: Br J Dermatol Source Type: research

Methotrexate restores the function of peripheral blood Treg cells in psoriasis vulgaris via CD73/AMPK/mTOR pathway.
CONCLUSION: We speculate that MTX can restore the immunosuppressive function of Treg cells through upregulating CD73, activating AMPK, and inactivating the mTOR pathway. These findings may partly explain the mechanism by which MTX treats psoriasis. This article is protected by copyright. All rights reserved. PMID: 29572822 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 23, 2018 Category: Dermatology Authors: Yan K, Xu W, Huang Y, Zhang Z, Huang Q, Xin KZ, Ma Y, Han L Tags: Br J Dermatol Source Type: research

Drug survival of secukinumab for moderate-to-severe plaque psoriasis.
This article is protected by copyright. All rights reserved. PMID: 29569720 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 23, 2018 Category: Dermatology Authors: Lee EB, Reynolds KA, Pithadia DJ, Wu JJ Tags: Br J Dermatol Source Type: research

Risk of basal cell carcinoma in a randomized clinical trial of aspirin and folic acid for the prevention of colorectal adenomas.
CONCLUSIONS: Neither aspirin nor folic acid treatment had a statistically significant effect on BCC risk. Subgroup analysis by skin cancer history suggested that chemopreventive effects of nonsteroidal anti-inflammatory drugs observed in previous studies may be specific to those at high risk for BCC. This article is protected by copyright. All rights reserved. PMID: 29570772 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 23, 2018 Category: Dermatology Authors: Passarelli MN, Barry EL, Zhang D, Gangar P, Rees JR, Bresalier RS, McKeown-Eyssen G, Karagas MR, Baron JA Tags: Br J Dermatol Source Type: research

Surgical re-excision versus observation for histologically dysplastic nevi: A Systematic Review of Associated Clinical Outcomes.
This article is protected by copyright. All rights reserved. PMID: 29570779 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 23, 2018 Category: Dermatology Authors: Vuong KT, Walker J, Powell H, Thomas NE, Jonas DE, Adamson AS Tags: Br J Dermatol Source Type: research

Inherited pulmonary cylindromas: Extending the phenotype of CYLD mutation carriers.
CONCLUSION: Pulmonary cylindromas are an unrecognised, but infrequently symptomatic, aspect of the phenotype in these patients that can have implications for patient care. They should be considered in patients with a high tumour burden that present with respiratory symptoms, and where appropriate monitored with serial imaging. This article is protected by copyright. All rights reserved. PMID: 29569226 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 22, 2018 Category: Dermatology Authors: Brown SM, Arefi M, Stones R, Loo PS, Barnard S, Bloxham C, Stefanos N, Langtry JAA, Worthy S, Calonje E, Husain A, Rajan N Tags: Br J Dermatol Source Type: research

Clinical and dermoscopic features of Spitz nevus by sex, age and anatomical site: a study of 913 Spitz naevi.
This article is protected by copyright. All rights reserved. PMID: 29569227 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 22, 2018 Category: Dermatology Authors: Scalvenzi M, Costa C, De Fata Salvatores G, Cappello M, Villani A Tags: Br J Dermatol Source Type: research

Diagnostic accuracy of dermatofluoroscopy in cutaneous melanoma detection: Results of a prospective multicentre clinical study in 476 pigmented lesions.
CONCLUSION: Dermatofluoroscopy is a safe and accurate diagnostic method to aid physicians in diagnosing cutaneous melanoma. Limitations arise from largely amelanotic or regressing lesions lacking sufficient melanin fluorescence. This article is protected by copyright. All rights reserved. PMID: 29569229 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 22, 2018 Category: Dermatology Authors: Forschner A, Keim U, Hofmann M, Spänkuch I, Lomberg D, Weide B, Tampouri I, Eigentler T, Fink C, Garbe C, Haenssle HA Tags: Br J Dermatol Source Type: research

Cumulative risk of skin tumours in patients with Lynch syndrome.
This article is protected by copyright. All rights reserved. PMID: 29542113 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 15, 2018 Category: Dermatology Authors: Adan F, Crijns MB, Zandstra WSE, Bekkenk MW, Bleeker FE, Dekker E, van Leerdam ME Tags: Br J Dermatol Source Type: research

Demodex mites modulate sebocyte immune reaction: Possible role in the pathogenesis of rosacea.
This article is protected by copyright. All rights reserved. PMID: 29532463 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 12, 2018 Category: Dermatology Authors: Lacey N, Russell-Hallinan A, Zouboulis CC, Powell FC Tags: Br J Dermatol Source Type: research

Successful therapy of ocular rosacea with topical ivermectin.
This article is protected by copyright. All rights reserved. PMID: 29527668 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 12, 2018 Category: Dermatology Authors: Schaller M, Pietschke K Tags: Br J Dermatol Source Type: research

Cutaneous squamous cell carcinomas are associated with basal proliferating actinic keratoses.
a T Abstract BACKGROUND: In addition to the extent of atypical keratinocytes throughout the epidermis, actinic keratoses (AKs) are histologically characterized by downward directed basal layer expansion. It is not known if this growth pattern correlates with the risk of developing invasive squamous cell carcinoma (iSCC). OBJECTIVE: To characterize the prevalence of downward directed basal layer expansion of AKs adjacent to iSCC. METHODS: The epidermis overlying and adjacent to iSCCs was assessed histologically. We determined the histological grade (AKI-III), basal growth pattern (PROI-III) and accompanyi...
Source: The British Journal of Dermatology - March 11, 2018 Category: Dermatology Authors: Schmitz L, Gambichler T, Kost C, Gupta G, Stücker M, Stockfleth E, Dirschka T Tags: Br J Dermatol Source Type: research

Novel compound heterozygous mutations in KREMEN1 confirm it as a disease gene for ectodermal dysplasia.
This article is protected by copyright. All rights reserved. PMID: 29526031 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 11, 2018 Category: Dermatology Authors: Intarak N, Theerapanon T, Srijunbarl A, Suphapeetiporn K, Porntaveetus T, Shotelersuk V Tags: Br J Dermatol Source Type: research

Differential blood cellular profile in patients with moderate to severe psoriasis treated with classical systemic therapies: A step forward in personalised medicine.
This article is protected by copyright. All rights reserved. PMID: 29526036 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 11, 2018 Category: Dermatology Authors: Hernández-Breijo B, Jurado T, Rodríguez-Martín E, Martínez-Feito A, Plasencia-Rodríguez C, Balsa A, Alonso-Pacheco ML, Villar LM, Herranz-Pinto P, Pascual-Salcedo D Tags: Br J Dermatol Source Type: research

Recurrent erysipelas of the face with hyperimmune reaction to group C streptococcus.
This article is protected by copyright. All rights reserved. PMID: 29526042 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 11, 2018 Category: Dermatology Authors: Dequidt L, Jullie ML, Seneschal J, Werfel T, Taieb A Tags: Br J Dermatol Source Type: research

Population-based prevalence of Eosinophilic (Shulman's) Fasciitis: a capture-recapture study.
This article is protected by copyright. All rights reserved. PMID: 29526049 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 11, 2018 Category: Dermatology Authors: Spielmann L, Arnaud L, Severac F, Messer L, Mahé A, Meyer A, Lannes B, Lipsker D, Sibilia J Tags: Br J Dermatol Source Type: research

Pulmonary function in subjects with psoriasis: A cross-sectional population study.
This article is protected by copyright. All rights reserved. PMID: 29526054 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 11, 2018 Category: Dermatology Authors: Hansen PR, Isaksen JL, Jemec GB, Kanters JK, Ellervik C Tags: Br J Dermatol Source Type: research

(Meth)acrylate allergy: frequently missed?
PMID: 29524210 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 10, 2018 Category: Dermatology Authors: Rolls S, Rajan S, Shah A, Bourke JF, Chowdhury MM, Ghaffar SA, Green C, Johnston GA, Orton DI, Reckling C, Stone NM, Wilkinson SM, Buckley DA Tags: Br J Dermatol Source Type: research

Changes in filaggrin degradation products and corneocyte surface texture by season.
CONCLUSIONS: Seasonal effects on NMF and DTI on the cheeks and hands were found, suggesting an influence of climatic factors at the biochemical and ultrastructural levels. Significant variations were also observed regarding age and sex, making it difficult to draw firm conclusions. Our study adds new pieces to the puzzle of seasonal differences in xerosis and dermatitis. PMID: 29512138 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 7, 2018 Category: Dermatology Authors: Engebretsen KA, Kezic S, Riethmüller C, Franz J, Jakasa I, Hedengran A, Linneberg A, Johansen JD, Thyssen JP Tags: Br J Dermatol Source Type: research

Malassezia species retrieved from skin with pityriasis versicolor, seborrheic dermatitis and skin free of lesions: a comparison of two sampling methods.
This article is protected by copyright. All rights reserved. PMID: 29505089 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 5, 2018 Category: Dermatology Authors: Pedrosa AF, Lisboa C, Faria-Ramos I, Silva RM, Miranda IM, Rodrigues AG Tags: Br J Dermatol Source Type: research

Punctate palmoplantar keratoderma: an unusual mutation causing an unusual phenotype.
This article is protected by copyright. All rights reserved. PMID: 29494755 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2018 Category: Dermatology Authors: Vodo D, Sarig O, Jeddah D, Malchin N, Eskin-Schwarz M, Mohamad J, Rabinowitz T, Goldberg I, Shomron N, Khamaysi Z, Bergman R, Sprecher E Tags: Br J Dermatol Source Type: research

A rare BRAF T599dup mutation conferring sensitivity to BRAF inhibitor in a patient with metastatic melanoma.
This article is protected by copyright. All rights reserved. PMID: 29494756 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2018 Category: Dermatology Authors: Marchand A, Tallet A, Collin C, Cormier B, Venel Y, Miquelestorena-Standley E, Machet L Tags: Br J Dermatol Source Type: research

Evaluation of treatment results in multifocal primary cutaneous anaplastic large cell lymphoma: Report of the Dutch Cutaneous Lymphoma Group.
CONCLUSION: Patients with ≤5 lesions should be treated with low-dose RT (2x4 Gy). Maintenance low-dose MTX (20 mg/week) is a suitable option in patients with>5 lesions. Targeted therapies may be considered in rare patients refractory to MTX or patients developing extracutaneous disease. This article is protected by copyright. All rights reserved. PMID: 29494757 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2018 Category: Dermatology Authors: Melchers RC, Willemze R, Bekkenk MW, de Haas ERM, Horvath B, van Rossum MM, Sanders CJG, Veraart JCJM, Vermeer MH, Quint KD Tags: Br J Dermatol Source Type: research

Genome-wide association study identifies three novel susceptibility loci for systemic lupus erythematosus in Han Chinese.
This article is protected by copyright. All rights reserved. PMID: 29494758 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2018 Category: Dermatology Authors: Liu L, Zuo X, Zhu Z, Wen L, Yang C, Zhu C, Tang L, Cheng Y, Chen M, Zhou F, Zheng X, Wang W, Yin X, Tang H, Sun L, Yang S, Sheng Y, Cui Y, Zhang X Tags: Br J Dermatol Source Type: research

Itch in dermatomyositis: the role of increased skin interleukin-31.
CONCLUSION: Increased skin IL-31 may play a role in DM-associated itch, and ongoing trials will evaluate the effects of systemic treatment on IL-31 and itch in DM. This article is protected by copyright. All rights reserved. PMID: 29494763 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2018 Category: Dermatology Authors: Kim HJ, Bonciani D, Zeidi M, Pena SM, Tiao J, Sahu S, Werth VP Tags: Br J Dermatol Source Type: research

Impact of Previous Biologic Use on Efficacy and Safety of Brodalumab and Ustekinumab in Patients with Moderate-to-Severe Plaque Psoriasis: Integrated Analysis of AMAGINE-2 and AMAGINE-3.
Abstract BACKGROUND: Biologics used increasingly used for treating moderate-to-severe psoriasis. Efficacy may differ in patients with previous biologics exposure. OBJECTIVE: To investigate the impact of previous biologic exposure on efficacy and safety of brodalumab and ustekinumab in moderate-to-severe plaque psoriasis. METHODS: Two placebo- and ustekinumab-controlled phase 3 clinical trials. Initial 12-week induction phase where patients were treated with brodalumab (210mg Q2W or 140mg Q2W), ustekinumab or placebo. Efficacy endpoints included: Psoriasis Area and Severity Index (PASI 75) and Physician's...
Source: The British Journal of Dermatology - February 28, 2018 Category: Dermatology Authors: Papp KA, Gordon KB, Langley RG, Lebwohl MG, Gottlieb AB, Rastogi S, Pillai R, Israel RJ Tags: Br J Dermatol Source Type: research

Effect of atopic skin stressors on natural moisturizing factors and cytokines in healthy adult epidermis.
CONCLUSION: Based on experimental exposure to selected atopic skin stressors such as different water types, allergens and SEB, we conclude that NMF levels are decreased along with increased secretion of various skin cytokines in healthy individuals. Our data highlight environmental factors that might play a role in AD pathophysiology, but needs confirmation in AD patients. This article is protected by copyright. All rights reserved. PMID: 29485689 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 27, 2018 Category: Dermatology Authors: Engebretsen KA, Kezic S, Jakasa I, Hedengran A, Linneberg A, Skov L, Johansen JD, Thyssen JP Tags: Br J Dermatol Source Type: research

Globular adiponectin acts as a melanogenic signal in human epidermal melanocytes.
CONCLUSIONS: These findings suggest that gAd contributes to epidermal homeostasis via its effect on melanocyte biology, and products of adipose tissue could affect epidermal biology. This article is protected by copyright. All rights reserved. PMID: 29485733 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 27, 2018 Category: Dermatology Authors: Kim Y, Cho JY, Oh SW, Kang M, Lee SE, Jung E, Park YS, Lee J Tags: Br J Dermatol Source Type: research

Safety and efficacy of biologic therapies in psoriatic patientswith alcoholic cirrhosis: a French retrospective study of 23 cases.
This article is protected by copyright. All rights reserved. PMID: 29480522 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 26, 2018 Category: Dermatology Authors: Begon E, Beneton N, Poiraud C, Droitcourt C, Jacobzone C, Vermersch-Langlin A, Descamps V, Perrot J, Khemis A, Pallure V, Fougerousse AC, Sigal-Grinberg M, Schmutz JC, Goujon C, Reguiai Z Tags: Br J Dermatol Source Type: research

Diphencyclopropenone (DPCP) for alopecia areata: a UK survey.
Abstract Alopecia areata (AA) is a T-cell mediated autoimmune hair loss condition with an estimated lifetime risk of 1.7%. It is characterized clinically by sudden-onset non-inflammatory hair loss that may occur at any site. The disease course is unpredictable with many patients experiencing spontaneous re-growth along with episodes of further loss. Unfortunately, around a fifth of patients presenting with patchy alopecia will progress to complete scalp (alopecia totalis (AT)) or scalp & body (alopecia universalis (AU)) hair loss from which spontaneous regrowth is rare (
Source: The British Journal of Dermatology - February 26, 2018 Category: Dermatology Authors: Karanovic S, Harries M, Kaur MR Tags: Br J Dermatol Source Type: research

Unique clinical and serological features of bullous pemphigoid associated with dipeptidyl peptidase-4 inhibitors.
This article is protected by copyright. All rights reserved. PMID: 29478242 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 25, 2018 Category: Dermatology Authors: Horikawa H, Kurihara Y, Funakoshi T, Umegaki-Arao N, Takahashi H, Kubo A, Tanikawa A, Kodani N, Minami Y, Meguro S, Itoh H, Izumi K, Nishie W, Shimizu H, Amagai M, Yamagami J Tags: Br J Dermatol Source Type: research

Effectiveness of Systemic Treatments for Pyoderma Gangrenosum:A Systematic Review of Observational Studies & Clinical Trials.
CONCLUSIONS: Systemic corticosteroids, cyclosporine, infliximab, and canakinumab had the most evidence in treating PG. However, current literature is limited to small and lower-quality studies with substantial heterogeneity. This article is protected by copyright. All rights reserved. PMID: 29478243 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 25, 2018 Category: Dermatology Authors: Partridge ACR, Bai JW, Rosen CF, Walsh SR, Gulliver WP, Fleming P Tags: Br J Dermatol Source Type: research

Tanning Addiction: Conceptualisation, Assessment, and Correlates.
Abstract BACKGROUND: Research into problematic tanning (or 'tanning addiction') has markedly increased over the past few years. Although several excessive tanning instruments exist, most of these are psychometrically poor, not theoretically anchored, and have mainly been used on small samples. OBJECTIVE: Against this background, a new tanning addiction scale was developed based on a specific theoretical approach utilising core addiction criteria. METHODS: A scale comprising seven items (i.e. salience/craving, mood modification, tolerance, withdrawal, conflict, relapse/loss of control, and problems) was a...
Source: The British Journal of Dermatology - February 25, 2018 Category: Dermatology Authors: Andreassen CS, Pallesen S, Torsheim T, Demetrovics Z, Griffiths MD Tags: Br J Dermatol Source Type: research

Incidence and Prevalence of Rosacea: A Systematic Review and Meta-Analysis.
CONCLUSION: We estimated the global prevalence of rosacea based on published data and found that 5.46% of the adult population is affected. However, the prevalence of rosacea depended on the diagnostic method with higher estimates in questionnaire studies and lower estimates in health registries. This article is protected by copyright. All rights reserved. PMID: 29478264 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 25, 2018 Category: Dermatology Authors: Gether L, Overgaard LK, Egeberg A, Thyssen JP Tags: Br J Dermatol Source Type: research

Novel in vivo observations of scrotal Nannizzia gypsea infection.
This article is protected by copyright. All rights reserved. PMID: 29478279 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 25, 2018 Category: Dermatology Authors: Xia XJ, Zhang Y, Zhong Y, Sang B, Li QP, Wang M, Lv WW, Zhi HL, Wang XD, Shen H, Liu ZH Tags: Br J Dermatol Source Type: research

Incidence of Sexual Dysfunction Among Patients with Hidradenitis Suppurativa: a population based retrospective analysis.
This article is protected by copyright. All rights reserved. PMID: 29478285 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 25, 2018 Category: Dermatology Authors: Slyper M, Strunk A, Garg A Tags: Br J Dermatol Source Type: research

Association between childhood atopic dermatitis, cutaneous, extracutaneous and systemic infections.
This article is protected by copyright. All rights reserved. PMID: 29478295 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 25, 2018 Category: Dermatology Authors: Narla S, Silverberg JI Tags: Br J Dermatol Source Type: research

Use of emollients and topical glucocorticoids among adolescents with eczema - datafrom the population-based birth cohort BAMSE.
CONCLUSIONS: This population-based study indicates that adolescents with eczema are undertreated or completely untreated, even those with severe eczema. This article is protected by copyright. All rights reserved. PMID: 29478304 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 25, 2018 Category: Dermatology Authors: Lundin S, Wahlgren CF, Bergström A, Johansson EK, Dahlén E, Andersson N, Kull I Tags: Br J Dermatol Source Type: research

Altered density, composition and microanatomical distribution of infiltrating immune cells in cutaneous squamous cell carcinoma of organ transplant recipients.
CONCLUSIONS: Immune cells infiltrates within SCC and at defined ROI of tumor-surrounding skin in OTR differ markedly in their composition and microanatomical distribution compared to tumors arising in IC. Our findings substantially broaden the understanding of how long-term systemic immunosuppression modulates the local inflammatory microenvironment in the skin and at the site of invasive SCC. This article is protected by copyright. All rights reserved. PMID: 29479687 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 25, 2018 Category: Dermatology Authors: Strobel SB, Safferling K, Lahrmann B, Hoffmann JH, Enk AH, Hadaschik EN, Grabe N, Lonsdorf AS Tags: Br J Dermatol Source Type: research

Cost-effectiveness of omalizumab for the treatment of Chronic Spontaneous Urticaria.
CONCLUSIONS: Omalizumab is cost-effective compared to SoC. The outcomes of this study were used to establish omalizumab as third-line treatment in the Dutch treatment guidelines for CSU. This article is protected by copyright. All rights reserved. PMID: 29476533 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 24, 2018 Category: Dermatology Authors: Kanters TA, Thio HB, Hakkaart L Tags: Br J Dermatol Source Type: research

Comparison of patient (POEM), observer (EASI, SASSAD, TIS) and corneometry measures of emollient effectiveness in children with eczema: findings from the COMET feasibility Trial.
CONCLUSIONS: Except for corneometry, all measures appear to change in relation to emollient use over time and correlate well with themselves. POEM demonstrated the greatest range of scores at baseline and change in eczema severity over the first 28 days. This article is protected by copyright. All rights reserved. PMID: 29476542 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 24, 2018 Category: Dermatology Authors: Ridd MJ, Gaunt DM, Guy RH, Redmond NM, Garfield K, Hollinghurst S, Ball N, Shaw L, Purdy S, Metcalfe C Tags: Br J Dermatol Source Type: research

A randomized split-scalp study comparing Calcipotriol assisted MAL-PDT with Conventional MAL-PDT for the treatment of Actinic Keratosis.
Abstract BACKGROUND: Topical photodynamic therapy (PDT) is an approved treatment for actinic keratosis (AK). To enhance the efficacy of PDT for AKs, physical (ablative lasers and microneedling) and chemical (pro-differentiating drugs) pretreatments have been suggested. OBJECTIVES: To compare the efficacy and safety of the combination of topical calcipotriol (CAL) before methylaminolevulinate (MAL)-PDT for AKs of the scalp versus conventional MAL-PDT in a randomized controlled-clinical trial. MATERIALS AND METHODS: Twenty patients with multiple AKs on the scalp were randomized to receive conventional MAL ...
Source: The British Journal of Dermatology - February 24, 2018 Category: Dermatology Authors: Torezan L, Grinblat B, Haedersdal M, Valente N, Festa-Neto C, Szeimies RM Tags: Br J Dermatol Source Type: research

Comorbidities of pyoderma gangrenosum: a retrospective multicentric analysis of 126 patients.
This article is protected by copyright. All rights reserved. PMID: 29453858 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 17, 2018 Category: Dermatology Authors: Gillard M, Anuset D, Maillard H, Senet P, Cuny JF, Mahe E, Sin C, Dessiner F, Goujon E, Journet-Tollhupp J, Debure C, Dabouz F, Develter T, Bernard P, Lok C, Modiano P, et le Groupe d'Angiodermatologie de la SFD Tags: Br J Dermatol Source Type: research

"It's a traumatic illness, traumatic to witness." A qualitative study of the experiences of bereaved family caregivers of patients with cutaneous T-cell lymphoma.
CONCLUSIONS: Family caregivers should be considered part of the wider healthcare team, acknowledging their multiple roles and the challenges they encounter in looking after their relative with CTCL as the disease progresses. Their experiences highlight the importance of organisational flexibility and of good communication between health care providers in advanced CTCL. This article is protected by copyright. All rights reserved. PMID: 29451670 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 16, 2018 Category: Dermatology Authors: Orlowska D, Selman LE, Beynon T, Radcliffe E, Whittaker S, Child F, Harding R Tags: Br J Dermatol Source Type: research

The Validity of the Diagnostic Code for Pyoderma Gangrenosum in an Electronic Database.
This article is protected by copyright. All rights reserved. PMID: 29451671 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 16, 2018 Category: Dermatology Authors: Lockwood SJ, Li DG, Butler D, Tsiaras W, Joyce C, Mostaghimi A Tags: Br J Dermatol Source Type: research

Successful therapy of Pyoderma gangrenosum with a JAK2 inhibitor.
This article is protected by copyright. All rights reserved. PMID: 29451690 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 16, 2018 Category: Dermatology Authors: Nasifoglu S, Heinrich B, Welzel J Tags: Br J Dermatol Source Type: research

Aquagenic Wrinkling of the Palms in Patients with Cystic Fibrosis.
This article is protected by copyright. All rights reserved. PMID: 29451691 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 16, 2018 Category: Dermatology Authors: Kaiser H, Brustad N, Pressler T, Bygum A Tags: Br J Dermatol Source Type: research

Acute psychosocial stress downregulates N-Methyl-d-aspartate receptors (NMDAR) in healthy human skin.
This article is protected by copyright. All rights reserved. PMID: 29451693 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 16, 2018 Category: Dermatology Authors: Hunter HJA, Morsman E, Mellody KT, Ogden SK, Zeef LAH, Hayes A, Griffiths CEM, Kleyn CE Tags: Br J Dermatol Source Type: research

Children with Facial Morphea Managing Everyday Life: A Qualitative Study.
CONCLUSION: Understanding what it is like to live with facial morphea from the perspectives of children and parents is important for devising ways to support children with facial morphea to achieve a better quality of life. Health care providers can help families access resources to manage anxiety, deal with bullying and construct adequate explanations of facial morphea, as well as providing opportunities for peer support. This article is protected by copyright. All rights reserved. PMID: 29451694 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 16, 2018 Category: Dermatology Authors: Stasiulis E, Gladstone B, Boydell K, O'Brien C, Pope E, Laxer R Tags: Br J Dermatol Source Type: research