Long non-coding RNA polymorphisms influence susceptibility to endemic pemphigus foliaceus.
er ML Abstract BACKGROUND: Pemphigus foliaceus (PF) is an epidermal autoimmune disease, characterized by the presence of autoantibodies against the desmosomal protein desmoglein 1. Genetic and environmental factors contribute to PF, a complex disease that is endemic in Brazil and Colombia and neighbouring countries, and in Tunisia. Long non-coding RNAs (lncRNAs) may participate in gene regulation by interacting with DNA, proteins, and other RNAs. Dysregulation of lncRNAs has recently been recognized as an important co-player in the onset or progression of complex diseases. In addition, single-nucleotide polymorphi...
Source: The British Journal of Dermatology - January 17, 2019 Category: Dermatology Authors: Lobo-Alves SC, Augusto DG, Magalhães WCS, Tarazona-Santos E, Lima-Costa MF, Barreto ML, Horta BL, de Almeida RC, Petzl-Erler ML Tags: Br J Dermatol Source Type: research

British Association of Dermatologists guidelines for the safe and effective prescribing of oral ciclosporin in dermatology 2018.
This article is protected by copyright. All rights reserved. PMID: 30653672 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 17, 2019 Category: Dermatology Authors: Berth-Jones J, Exton LS, Ladoyanni E, Mohd Mustapa MF, Tebbs V, Yesudian PD, Levell NJ Tags: Br J Dermatol Source Type: research

Identification of titanium dioxide on the hair shaft of patients with and without frontal fibrosing alopecia: A pilot study of 20 patients.
This article is protected by copyright. All rights reserved. PMID: 30648256 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 16, 2019 Category: Dermatology Authors: Thompson CT, Chen ZQ, Kolivras A, Tosti A Tags: Br J Dermatol Source Type: research

Decreased recognition of paraneoplastic pemphigus in patients previously treated with anti-CD 20 monoclonal antibodies.
PMID: 30648258 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 15, 2019 Category: Dermatology Authors: Kwatra SG, Boozalis E, Pasieka H, Anhalt GJ Tags: Br J Dermatol Source Type: research

Identification of small peptides and glycinamide that inhibit melanin synthesis using a positional scanning synthetic peptide combinatorial library.
CONCLUSIONS: Small peptides, including glycinamide and tryptophanyl glycinamide, are potent antimelanogenic agents with potential value for the treatment of skin hyperpigmentation. This article is protected by copyright. All rights reserved. PMID: 30637717 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 13, 2019 Category: Dermatology Authors: Kim JH, Seok JK, Kim YM, Boo YC Tags: Br J Dermatol Source Type: research

Validation and Reliability of a Disease-Specific Quality of Life Measure in Patients with Cutaneous Lupus Erythematosus: CLEQoL.
Abstract BACKGROUND: Cutaneous lupus erythematosus (CLE) is a potentially disfiguring, chronic autoimmune disease with extremely variable skin manifestations, negatively affecting quality of life (QoL) of patients. Patient-reported outcome (PRO) measures used in assessing QoL in CLE patients have been either generic or developed without input from patients with CLE. OBJECTIVES: To demonstrate the reliability and validity of a disease-specific QoL measure for CLE - the cutaneous lupus erythematosus quality of life (CLEQoL). METHODS: A total of 101 patients with a clinical diagnosis of CLE were recruited, ...
Source: The British Journal of Dermatology - January 13, 2019 Category: Dermatology Authors: Ogunsanya ME, Cho SK, Hudson A, Chong BF Tags: Br J Dermatol Source Type: research

Dry skin and skin barrier in early infancy.
This article is protected by copyright. All rights reserved. PMID: 30637724 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 13, 2019 Category: Dermatology Authors: Rehbinder EM, Winger AJ, Landrø L, Asarnoj A, Berents TL, Carlsen KH, Hedlin G, Jonassen CM, Nordlund B, Sandvik L, Skjerven HO, Söderhäll C, Vettukattil R, Carlsen KCL, study group Tags: Br J Dermatol Source Type: research

Anatomical Site Differences of Sodium Laurylsulphate Induced Irritation: randomised controlled trial.
CONCLUSION: Skins' reaction to irritant and recovery were dependant on anatomical location. Location where testing was conducted should always be reported as treatments tested across different locations could not be directly compared to each other. This article is protected by copyright. All rights reserved. PMID: 30637727 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 13, 2019 Category: Dermatology Authors: Leskur D, Bukić J, Petrić A, Zekan L, Rušić D, Šešelja Perišin A, Petrić I, Stipić M, Puizina-Ivić N, Modun D Tags: Br J Dermatol Source Type: research

Healthcare utilization and management of actinic keratosis in primary and secondary care: a complementary database analysis.
CONCLUSIONS: AK management seems to diverge from guidelines in both primary and secondary care. Underutilization of field treatments, inappropriate treatments and high referral rates without proper risk stratification in primary care, combined with extensive follow-up in secondary care result in inefficient use of healthcare resources and overburdening in secondary care. Efforts directed to better risk differentiation and guideline adherence may prove useful in increasing the efficiency in AK management. This article is protected by copyright. All rights reserved. PMID: 30636037 [PubMed - as supplied by publisher] (So...
Source: The British Journal of Dermatology - January 12, 2019 Category: Dermatology Authors: Noels EC, Hollestein LM, van Egmond S, Lugtenberg M, van Nistelrooij LPJ, Bindels P, van der Lei J, Stern RS, Nijsten T, Wakkee M Tags: Br J Dermatol Source Type: research

Risankizumab versus ustekinumab for plaque psoriasis: a critical appraisal.
This study consisted of two replicate phase 3, double-blinded randomised-controlled trials (UltIMMa-1 and UltIMMa-2) conducted across 139 centres in Australia, Austria, Belgium, Canada, Czech Republic, France, Germany, Japan, Mexico, Poland, Portugal, South Korea, Spain and the USA. STUDY EXPOSURE: Patients with a minimum 6 month history of chronic plaque psoriasis were randomly assigned to receive either 150 mg risankizumab, 45 mg or 90 mg ustekinumab or placebo. Prior to this, each group was also stratified by weight (either more than or less than 100kg) and previous exposure to tumour necrosis factor inhibitor. Tho...
Source: The British Journal of Dermatology - January 11, 2019 Category: Dermatology Authors: Al-Janabi A, Jabbar-Lopez ZK, Griffiths CEM, Yiu ZZN Tags: Br J Dermatol Source Type: research

Case Series of Cutaneous Mucormycosis in Setting of Herpesviridae Infection.
This article is protected by copyright. All rights reserved. PMID: 30633321 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 11, 2019 Category: Dermatology Authors: McKenzie S, Zang P, Blackcloud P, Cohen B, Truong A, Worswick S, Arzeno J Tags: Br J Dermatol Source Type: research

Dark skin phototype is associated with more severe ocular complications of Stevens-Johnson syndrome and toxic epidermal necrolysis.
This article is protected by copyright. All rights reserved. PMID: 30633324 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 11, 2019 Category: Dermatology Authors: Thorel D, Delcampe A, Ingen-Housz-Oro S, Hajj C, Gabison E, Chosidow O, Wolkenstein P, Royer G, Ezzedine K, Muraine M, Gueudry J Tags: Br J Dermatol Source Type: research

Effect of dupilumab on atopic manifestations in patients treated for atopic dermatitis in real life practice.
This article is protected by copyright. All rights reserved. PMID: 30633329 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 11, 2019 Category: Dermatology Authors: Tauber M, Apoil PA, Richet C, Laurent J, De Bonnecaze G, Mouchon E, Cassagne M, Marguery MC, Hegazy S, Konstantinou MP, Severino M, Uthurriague C, Giordano-Labadie F, Didier A, Paul C Tags: Br J Dermatol Source Type: research

Persistence and Effectiveness of Non-Biologic Systemic Therapies for Moderate-Severe Psoriasis in Adults: a Systematic Review.
CONCLUSIONS: The comparative persistence and effectiveness of acitretin, ciclosporin, FAE and methotrexate in real-world clinical practice in the past decade cannot be well-described due to the inconsistency of the methods used. This article is protected by copyright. All rights reserved. PMID: 30628069 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 10, 2019 Category: Dermatology Authors: Mason KJ, Williams S, Yiu ZZN, McElhone K, Ashcroft DM, Kleyn CE, Jabbar-Lopez ZK, Owen CM, Reynolds NJ, Smith CH, Wilson N, Warren RB, Griffiths CEM Tags: Br J Dermatol Source Type: research

Thyroid function in psoriasis.
This article is protected by copyright. All rights reserved. PMID: 30629295 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 10, 2019 Category: Dermatology Authors: Hansen PR, Isaksen JL, Borut Jemec G, Ellervik C, Kim Kanters J Tags: Br J Dermatol Source Type: research

A randomised phase II study evaluating vismodegib as neoadjuvant treatment of basal cell carcinoma preceding Mohs micrographic surgery: results and lessons learned.
This article is protected by copyright. All rights reserved. PMID: 30628055 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 9, 2019 Category: Dermatology Authors: Soon SL, Ibrahim SF, Arron ST Tags: Br J Dermatol Source Type: research

Efficacy and safety of PAC-14028 cream - a novel, topical, nonsteroidal, selective TRPV1 antagonist in patients with mild-to-moderate atopic dermatitis: a phase IIb randomized trial.
Abstract BACKGROUND: Transient receptor potential vanilloid subfamily, member 1 (TRPV1) may play an important role in pruritus and inflammation induction in atopic dermatitis (AD). The treatment effect of TRPV1 antagonist via topical application in patients with AD remains unknown. OBJECTIVES: To assess the clinical efficacy and safety of PAC-14028, a TRPV1 antagonist, via topical application in patients with AD. METHODS: In this 8-week, phase IIb, randomized, double-blind, multicentre, vehicle-controlled study, patients with mild-to-moderate AD were randomized to receive PAC-14028 cream 0·1%, 0&m...
Source: The British Journal of Dermatology - January 8, 2019 Category: Dermatology Authors: Lee YW, Won CH, Jung K, Nam HJ, Choi G, Park YH, Park M, Kim B Tags: Br J Dermatol Source Type: research

The Impact of Stress on Epidermal Barrier Function - An Evidence-Based Review.
This article is protected by copyright. All rights reserved. PMID: 30614527 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 7, 2019 Category: Dermatology Authors: Maarouf M, Maarouf CL, Yosipovitch G, Shi VY Tags: Br J Dermatol Source Type: research

Serum and blister-fluid elevation and decreased epidermal content of HMGB1 protein in drug-induced Stevens Johnson syndrome/toxic epidermal necrolysis.
med M Abstract High-mobility group box 1 (HMGB1) is a damage-associated molecular-pattern protein indicative of cell/tissue injury and innate immune response. Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) are serious, immune-mediated skin-blistering conditions characterised by widespread keratinocyte death and epidermal detachment. The purpose of the study was to determine: a) serum and/or blister-fluid total HMGB1 levels in independent SJS/TEN cohorts: and b) HMGB1 expression in formalin-fixed, paraffin-embedded SJS/TEN skin vs. healthy and maculopapular exanthema (MPE). Total serum HMGB1 was qu...
Source: The British Journal of Dermatology - January 5, 2019 Category: Dermatology Authors: Carr DF, Wang CW, Bellón T, Ressel L, Nwikue G, Shrivastava V, Bergfeld W, Jorgensen AL, Chung WH, Pirmohamed M Tags: Br J Dermatol Source Type: research

Quantitative survey into value clarification of discussed treatment options among patients treated for basal-cell carcinoma.
This article is protected by copyright. All rights reserved. PMID: 30613956 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 5, 2019 Category: Dermatology Authors: van Delft LCJ, Essers BAB, Harnas S, Kelleners-Smeets NWJ Tags: Br J Dermatol Source Type: research

Prevalence and outcome of latent tuberculosis in patients receiving ixekizumab: Integrated safety analysis from 11 clinical trials of patients with plaque psoriasis.
This article is protected by copyright. All rights reserved. PMID: 30609008 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 4, 2019 Category: Dermatology Authors: Romiti R, Valenzuela F, Chouela EN, Xu W, Pangallo B, Moriarty SR, Gürbüz S, Riedl E Tags: Br J Dermatol Source Type: research

CONSORT 2010 statement: extension checklist for reporting within person randomised trials.
Abstract Evidence shows that the quality of reporting of randomised controlled trials (RCTs) is not optimal. The lack of transparent reporting impedes readers from judging the reliability and validity of trial findings and researchers from extracting information for systematic reviews and results in research waste. The Consolidated Standards of Reporting Trials (CONSORT) statement was developed to improve the reporting of RCTs. Within person trials are used for conditions that can affect two or more body sites, and are a useful and efficient tool because the comparisons between interventions are within people. Suc...
Source: The British Journal of Dermatology - January 4, 2019 Category: Dermatology Authors: Pandis N, Chung B, Scherer RW, Elbourne D, Altman DG Tags: Br J Dermatol Source Type: research

Incisional random skin biopsy, not punch biopsy, is an appropriate method for diagnosis of intravascular large B-cell lymphoma: A clinicopathological study of 25 patients.
This article is protected by copyright. All rights reserved. PMID: 30609011 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 4, 2019 Category: Dermatology Authors: Enzan N, Kitadate A, Tanaka A, Matsue K Tags: Br J Dermatol Source Type: research

Patch granuloma annulare:Clinicopathological characteristics and response to phototherapy.
This article is protected by copyright. All rights reserved. PMID: 30609014 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 4, 2019 Category: Dermatology Authors: Aichelburg MC, Pinkowicz A, Schuster C, Volc-Platzer B, Tanew A Tags: Br J Dermatol Source Type: research

Incidence of melanoma and outcomes of longitudinal melanonychia in a cohort of cases referred to a London dermatology department.
This article is protected by copyright. All rights reserved. PMID: 30609019 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 4, 2019 Category: Dermatology Authors: Jiyad Z, Akhras V Tags: Br J Dermatol Source Type: research

Clindamycin alone may be enough. Is it time to abandon rifampicin for hidradenitis suppurativa?
This article is protected by copyright. All rights reserved. PMID: 30604861 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 3, 2019 Category: Dermatology Authors: Caposiena Caro RD, Bianchi L Tags: Br J Dermatol Source Type: research

Ethnicity in Mycosis Fungoides: White patients present at an older age and with more advanced disease.
This article is protected by copyright. All rights reserved. PMID: 30604865 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 3, 2019 Category: Dermatology Authors: Scarisbrick JJ, Quaglino P, Prince HM, Kim YH, Willemze R, PROCLIPI Investigators Tags: Br J Dermatol Source Type: research

Clindamycin alone may be enough. Is it time to abandon rifampicin for hidradenitis suppurativa? Reply from authors.
This article is protected by copyright. All rights reserved. PMID: 30604869 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 3, 2019 Category: Dermatology Authors: Albrecht J, Barbaric J, Nast A Tags: Br J Dermatol Source Type: research

Response to Santer et  al article 'Views of oral antibiotics and advice seeking about acne: a qualitative study of online discussion forums' 2017 based on evidence obtained from The Acne Priority Setting Partnership (PSP).
This article is protected by copyright. All rights reserved. PMID: 30604870 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 3, 2019 Category: Dermatology Authors: Horton E, Lee N, Layton AM, Eady EA Tags: Br J Dermatol Source Type: research

Understanding racial disparities in mycosis fungoides through international collaborative studies.
This article is protected by copyright. All rights reserved. PMID: 30604871 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 3, 2019 Category: Dermatology Authors: Geller S, Lebowitz E, Pulitzer M, Myskowski PL Tags: Br J Dermatol Source Type: research

Tofacitinib: a new oral Janus kinase inhibitor for psoriasis.
PMID: 30604529 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 1, 2019 Category: Dermatology Authors: Fleming P Tags: Br J Dermatol Source Type: research

Targeting tryptophan transport and breakdown in basal cell carcinoma.
PMID: 30604530 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 1, 2019 Category: Dermatology Authors: O'Shaughnessy RFL Tags: Br J Dermatol Source Type: research

The devil is in the data: differences in drug persistence between SNIIRAM, the French national health insurance database, and psoriasis biologics intervention registers.
PMID: 30604531 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 1, 2019 Category: Dermatology Authors: Grantham HJ, Reynolds NJ Tags: Br J Dermatol Source Type: research

Image Gallery: Poikiloderma with neutropenia.
PMID: 30604532 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 1, 2019 Category: Dermatology Authors: Chen X, Yang Y, Lin Z Tags: Br J Dermatol Source Type: research

Recent developments in lymph node surgery for melanoma.
PMID: 30604533 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 1, 2019 Category: Dermatology Authors: van Akkooi ACJ, Hayes A Tags: Br J Dermatol Source Type: research

Image Gallery: Scabies incognito.
PMID: 30604534 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 1, 2019 Category: Dermatology Authors: Kjerkegaard U, Bygum A Tags: Br J Dermatol Source Type: research

Image Gallery: A case of porokeratosis ptychotropica.
PMID: 30604535 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 1, 2019 Category: Dermatology Authors: Sun JR, Li YR, Tu P, Chen XX, Wang Y Tags: Br J Dermatol Source Type: research

Highlights of the updated Dutch evidence- and consensus-based guideline on psoriasis 2017.
Veldkamp WR, Wakkee M, Nast A, Jacobs A, Rosumeck S, Spuls Chair PI PMID: 30604536 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 1, 2019 Category: Dermatology Authors: van der Kraaij GE, Balak DMW, Busard CI, van Cranenburgh OD, Chung Y, Driessen RJB, de Groot M, de Jong EMGJ, Kemperman PMJH, de Kort WJA, Karsch SA, Lamberts A, Lecluse LLA, van Lümig PPM, Menting SP, Prens EP, van den Reek JMPA, Seyger MMB, Thio HB, Ve Tags: Br J Dermatol Source Type: research

Antibody reactive to a novel autoantigen on the nondesmosomal keratinocyte surfaces leads to herpetiform pemphigus.
PMID: 30604537 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 1, 2019 Category: Dermatology Authors: Yuan H, Pan M Tags: Br J Dermatol Source Type: research

BJD Reviewers October 2017 - September 2018.
Authors: PMID: 30604538 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 1, 2019 Category: Dermatology Tags: Br J Dermatol Source Type: research

Adalimumab treatment for psoriasis - safety in numbers.
PMID: 30604539 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 1, 2019 Category: Dermatology Authors: Ryan C Tags: Br J Dermatol Source Type: research

What lessons can we learn from an apparent decrease in the use of topical drugs for psoriasis?
PMID: 30604540 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 1, 2019 Category: Dermatology Authors: Criado PR Tags: Br J Dermatol Source Type: research

'Surprisingly little evidence' on how best to treat actinic keratosis in organ transplant recipients.
PMID: 30604541 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 1, 2019 Category: Dermatology Authors: Werner RN, Nast A Tags: Br J Dermatol Source Type: research

Image Gallery: Red coral vascular pattern as a new dermoscopic clue for clear cell acanthoma.
PMID: 30604543 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 1, 2019 Category: Dermatology Authors: Lobato-Berezo A, Vidal Navarro A, Pujol RM Tags: Br J Dermatol Source Type: research

Dutch guidelines for psoriasis treatment.
PMID: 30604544 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 1, 2019 Category: Dermatology Authors: Ormerod AD Tags: Br J Dermatol Source Type: research

Omalizumab: living up to PROMises.
au AM PMID: 30604545 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 1, 2019 Category: Dermatology Authors: Giménez-Arnau AM Tags: Br J Dermatol Source Type: research

Professor Sidney Barski (1918-2018).
PMID: 30604546 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 1, 2019 Category: Dermatology Authors: Albrecht J Tags: Br J Dermatol Source Type: research

RASopathies and the skin.
PMID: 30604547 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 1, 2019 Category: Dermatology Authors: Moss C Tags: Br J Dermatol Source Type: research

Early laser intervention for improved appearance of surgical scars.
PMID: 30604548 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 1, 2019 Category: Dermatology Authors: Togsverd-Bo K Tags: Br J Dermatol Source Type: research

Increased risk of death in patients with psoriasis: disease or lifestyle?
PMID: 30604549 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - January 1, 2019 Category: Dermatology Authors: Danielsen K Tags: Br J Dermatol Source Type: research