The long road to valid outcomes in vitiligo.
PMID: 30821367 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2019 Category: Dermatology Authors: Wolkerstorfer A Tags: Br J Dermatol Source Type: research

Atopic dermatitis and educational achievements - what have we learned?
PMID: 30821368 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2019 Category: Dermatology Authors: Vittrup I, Thyssen JP Tags: Br J Dermatol Source Type: research

Image Gallery: Multiple disseminated nodules with dysaesthesia in the Mexican-American border.
mpo-Candiani J, Welsh O PMID: 30821369 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2019 Category: Dermatology Authors: García-Lozano JA, Villarreal-Villarreal CD, Franco-Márquez R, González-González SE, Ocampo-Candiani J, Welsh O Tags: Br J Dermatol Source Type: research

'En route' to precision medicine.
PMID: 30821370 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2019 Category: Dermatology Authors: Hijnen DJ Tags: Br J Dermatol Source Type: research

Atopic dermatitis: it's not just barrier dysfunction.
PMID: 30821371 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2019 Category: Dermatology Authors: Silverberg JI Tags: Br J Dermatol Source Type: research

Image Gallery: Multiple localized lipoatrophy in recessive dystrophic epidermolysis bullosa.
PMID: 30821372 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2019 Category: Dermatology Authors: Nohara T, Fujita Y, Takashima S, Natsuga K, Shimizu H Tags: Br J Dermatol Source Type: research

Cutaneous adnexal carcinomas, the forgotten skin cancers?
PMID: 30821374 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2019 Category: Dermatology Authors: Andersen YMF Tags: Br J Dermatol Source Type: research

Infrared spectroscopy could be a diagnostic tool in dermatology.
PMID: 30821375 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2019 Category: Dermatology Authors: Kumar S Tags: Br J Dermatol Source Type: research

Within-person studies - what, when and how?
PMID: 30821376 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2019 Category: Dermatology Authors: Gran S Tags: Br J Dermatol Source Type: research

Shining light on darker skins.
PMID: 30821377 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2019 Category: Dermatology Authors: Young AR Tags: Br J Dermatol Source Type: research

Image Gallery: Polymorphic lesions in a haematological patient.
e;ñez A, Borbujo-Martínez J PMID: 30821378 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2019 Category: Dermatology Authors: Rojas Farias FE, Martínez-Morán C, Khedaoui R, Esteban-Garrido E, Company Rodríguez-Quiroga J, Alique-Garcia S, Hernández-Núñez A, Borbujo-Martínez J Tags: Br J Dermatol Source Type: research

The case for greater vigilance in applying sunscreen during real-life sun exposure.
PMID: 30821379 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2019 Category: Dermatology Authors: Hart PH Tags: Br J Dermatol Source Type: research

Image Gallery: Recurrent bovine papular stomatitis virus infection diagnosed by nested polymerase chain reaction.
PMID: 30821380 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2019 Category: Dermatology Authors: Bianchi L, Tramontana M, Biondi F, Hansel K, Gallina L, Scagliarini A, Manuali E, Stingeni L Tags: Br J Dermatol Source Type: research

How to organize skin cancer care for organ transplant recipients.
PMID: 30821381 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2019 Category: Dermatology Authors: Gjersvik P Tags: Br J Dermatol Source Type: research

Useful components in the stratum corneum for assessment of atopic dermatitis.
PMID: 30821382 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2019 Category: Dermatology Authors: Furue M Tags: Br J Dermatol Source Type: research

Professor John Lloyd Burton, BSc, MD, FRCP: 1938-2018.
PMID: 30821383 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2019 Category: Dermatology Authors: Kennedy CTC Tags: Br J Dermatol Source Type: research

Dermatology inpatient care in the U.K.: rarely possible, hard to defend but occasionally essential.
PMID: 30821384 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2019 Category: Dermatology Authors: Finlay AY, Anstey AV Tags: Br J Dermatol Source Type: research

Updates in cutaneous lymphoma: evidence-based guidelines for the management of cutaneous lymphoma 2018.
PMID: 30821385 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2019 Category: Dermatology Authors: Wang Y, Bagot M Tags: Br J Dermatol Source Type: research

Beta blockers for infantile haemangiomas: where should we go from here?
PMID: 30821386 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2019 Category: Dermatology Authors: Mellerio JE Tags: Br J Dermatol Source Type: research

Genital psoriasis: the failure of dermatologists to identify genital involvement.
PMID: 30821387 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2019 Category: Dermatology Authors: Ryan C Tags: Br J Dermatol Source Type: research

Scoring pyoderma gangrenosum.
PMID: 30821389 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2019 Category: Dermatology Authors: Schreml S Tags: Br J Dermatol Source Type: research

Image Gallery: A case of gadolinium-associated plaques requiring confirmation with mass spectrometry.
PMID: 30821390 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2019 Category: Dermatology Authors: Olayiwola O, Ronkainen S, Miller D, High W, Farah RS Tags: Br J Dermatol Source Type: research

A critical appraisal and implications of the new National Institute for Health and Care Excellence guideline on dupilumab for treating moderate-to-severe atopic eczema.
PMID: 30821391 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2019 Category: Dermatology Authors: Weidinger S, Apfelbacher C Tags: Br J Dermatol Source Type: research

Congenital ichthyoses: there is always more to learn about managing these rare and complex diseases.
PMID: 30821392 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2019 Category: Dermatology Authors: Akiyama M Tags: Br J Dermatol Source Type: research

A rose is a rose: naevoid manifestations blur the boundary between naevus and classical gene defect in focal dermal hypoplasia.
PMID: 30821393 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2019 Category: Dermatology Authors: Traupe H Tags: Br J Dermatol Source Type: research

Can optical coherence tomography improve the management of basal cell carcinoma?
PMID: 30821394 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2019 Category: Dermatology Authors: Navarrete-Dechent C, Rajadhyaksha M, Nehal KS Tags: Br J Dermatol Source Type: research

Image Gallery: Dermoscopy of perianal molluscum contagiosum in a child caused by molluscum contagiosum virus subtype I.
PMID: 30821395 [PubMed - in process] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2019 Category: Dermatology Authors: Pradhan S, Ran X, Xu X, Yang Y, Lei S, Ran Y Tags: Br J Dermatol Source Type: research

A Standardisation Approach to Compare Treatment Safety and Effectiveness Outcomes between Clinical Trials and Real World Populations in Psoriasis.
CONCLUSIONS: Our results suggest that RCTs of biologic therapies in psoriasis patients are not fully representative of the real-world population, but this lack of external validity does not account for the efficacy-effectiveness gap. This article is protected by copyright. All rights reserved. PMID: 30822358 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2019 Category: Dermatology Authors: Yiu ZZN, Mason KJ, Barker JNWN, Hampton PJ, McElhone K, Smith CH, Warren RB, Griffiths CEM, Lunt M, Burden AD, BADBIR Study Group Tags: Br J Dermatol Source Type: research

Oxymatrine therapy inhibited epidermal cell proliferation and apoptosis in severe plaque psoriasis.
We examined the effect of oxymatrine treatment on cell proliferation and apoptosis in skin lesions of psoriasis. METHODS: Patients with severe plaque psoriasis were treated with oxymatrine or with acitretin. The skin lesions were stained with proliferating cell nuclear antigen (PCNA), Ki-67, Bcl-2, as well as examined by terminal deoxynucleotidyl transferase (TdT)-mediated dUTP nick end labeling (TUNEL). We performed correlations of the psoriasis area and severity index (PASI) and the proliferation and apoptosis index. RESULTS: Oxymatrine significantly reduced psoriasis the lesions as demonstrated by the reduced ...
Source: The British Journal of Dermatology - March 1, 2019 Category: Dermatology Authors: Shi HJ, Zhou H, Ma AL, Wang L, Gao Q, Zhang N, Song HB, Bo KP, Ma W Tags: Br J Dermatol Source Type: research

Differential expression of PD-1 according to the histologic differentiation of cutaneous squamous cell carcinoma.
This article is protected by copyright. All rights reserved. PMID: 30822360 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2019 Category: Dermatology Authors: Oh ST, Yang KJ, Lee JU, Bae JM, Park HJ, Kim JW, Park YM Tags: Br J Dermatol Source Type: research

Atrophic acne scar: A process from altered metabolism of elastic fibers and collagen fibers based on TGF- β1 signaling.
CONCLUSIONS: These results may provide a basis for understanding the pathogenesis of atrophic acne scarring. Reduction of excessive inflammation and TGF-β1 signaling in early acne lesions is expected to facilitate the protection of normal extracellular matrix metabolism and the prevention of atrophic scar formation ultimately. This article is protected by copyright. All rights reserved. PMID: 30822364 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2019 Category: Dermatology Authors: Moon J, Yoon JY, Yang JH, Kwon HH, Min S, Suh DH Tags: Br J Dermatol Source Type: research

Novel mutations in desmoglein 1: Focal palmoplantar keratoderma in milder phenotypes.
This article is protected by copyright. All rights reserved. PMID: 30822367 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2019 Category: Dermatology Authors: Zamiri M, Wilson NJ, O'Toole EA, Smith FJD Tags: Br J Dermatol Source Type: research

Different definitions of atopic dermatitis: Impact on prevalence estimates and associated risk factors.
CONCLUSION: Use of different definitions of AD results in substantial difference in prevalence estimates, the performance of prediction models, and association with risk factors. This article is protected by copyright. All rights reserved. PMID: 30822368 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2019 Category: Dermatology Authors: Nakamura T, Haider S, Colicino S, Murray CS, Holloway J, Simpson A, Cullinan P, Custovic A, STELAR investigators Tags: Br J Dermatol Source Type: research

Economic evaluation of a tailored therapist-guided internet-based cognitive behavioral treatment (ICBT) for patients with psoriasis: a randomized controlled trial.
CONCLUSIONS: While the ICBT intervention was not considered cost-effective in the overall sample, subgroup analyses indicated that it was cost-effective for patients with relatively high self-assessed disease severity or self-perceived impact of psoriasis on daily life. It may be clinically relevant to screen for these characteristics prior to ICBT, in order to offer cost-effective care. This article is protected by copyright. All rights reserved. PMID: 30822378 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2019 Category: Dermatology Authors: van Beugen S, Ferwerda M, van Middendorp H, Smit JV, Zeeuwen-Franssen MEJ, Kroft EBM, de Jong EMGJ, van de Kerkhof PCM, Kievit W, Evers AWM Tags: Br J Dermatol Source Type: research

Comprehensive analysis of β and γ Human Papillomaviruses in actinic keratosis and apparently healthy skin of elderly patients.
This article is protected by copyright. All rights reserved. PMID: 30825192 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2019 Category: Dermatology Authors: Donà MG, Chiantore MV, Gheit T, Fiorucci G, Vescio MF, La Rosa G, Accardi L, Costanzo G, Giuliani M, Romeo G, Rezza G, Tommasino M, Luzi F, Di Bonito P Tags: Br J Dermatol Source Type: research

Characteristics and prevalence of plaque psoriasis in patients with palmoplantar pustulosis.
CONCLUSIONS: This large observational study on patients with PPP provides detailed information regarding patient demographics, comorbidities, and medication use. The one-year prevalence of PPP varied in the three studied populations, possibly due to differences in diagnostics and recording practices. Psoriasis was frequently co-occurring in patients with PPP. This article is protected by copyright. All rights reserved. PMID: 30815849 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 28, 2019 Category: Dermatology Authors: Andersen YMF, Augustin M, Petersen J, Hagenström K, Mallbris L, Burge R, Egeberg A Tags: Br J Dermatol Source Type: research

miR-145-5p regulates fibrotic features of recessive dystrophic epidermolysis bullosa skin fibroblasts.
CONCLUSIONS: Our results highlight the pro-fibrotic role of miR-145-5p and its regulatory networks in RDEB, shedding light on novel disease pathomechanisms and targets for future therapeutic approaches. This article is protected by copyright. All rights reserved. PMID: 30816994 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 28, 2019 Category: Dermatology Authors: Condorelli AG, Logli E, Cianfarani F, Teson M, Diociaiuti A, El Hachem M, Zambruno G, Castiglia D, Odorisio T Tags: Br J Dermatol Source Type: research

Extending the phenotypic spectrum associated with mosaicism for GJB2 mutations.
This article is protected by copyright. All rights reserved. PMID: 30816995 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 28, 2019 Category: Dermatology Authors: Has C, Küsel J, Happle R, Steinke H, Technau-Hafsi K, Fischer J Tags: Br J Dermatol Source Type: research

Relapse of psoriatic arthritis in patients with active psoriasis swapped from TNF- α to IL-17A inhibitor.
This article is protected by copyright. All rights reserved. PMID: 30820927 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 28, 2019 Category: Dermatology Authors: Gisondi P, Geat D, Idolazzi L, Girolomoni G Tags: Br J Dermatol Source Type: research

Are drug intradermal tests dangerous to explore cross-reactivity and co-sensitization in DRESS?
This article is protected by copyright. All rights reserved. PMID: 30811579 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 27, 2019 Category: Dermatology Authors: Soria A, Hamelin A, de Risi Pugliese T, Amsler E, Barbaud A Tags: Br J Dermatol Source Type: research

Antipruritic effects of transient heat-stimulation on histaminergic and non-histaminergic itch.
Abstract BACKGROUND: Chronic itch is notoriously difficult to treat. Counter-stimuli are able to inhibit itch, but this principle is difficult to apply in clinical practice, and the mechanisms behind counter-stimulation-induced itch suppression in humans are unclear. OBJECTIVES: 1) To analyse the stimulus-response effects of transient heat stimuli on histaminergic and non-histaminergic itch; 2) to investigate whether the antipruritic effect depends on homotopic (peripheral mediation) versus heterotopic (central mediation) counter-stimulation relative to the itch provocation site. METHODS: 18 healthy subj...
Source: The British Journal of Dermatology - February 25, 2019 Category: Dermatology Authors: Riccio D, Andersen HH, Arendt-Nielsen L Tags: Br J Dermatol Source Type: research

Epidemiology and Dermatological Comorbidity of Seborrhoeic Dermatitis - Population-based Study in 161,000 Employees.
n M Abstract BACKGROUND: Seborrhoeic dermatitis (SD) is a common but epidemiologically poorly researched chronic skin disease. OBJECTIVES: To characterise the prevalence and dermatological comorbidity of SD in Germany. METHODS: In the course of voluntary company skin checks, full body examinations were carried out in more than 500 companies by experienced dermatologists and documented electronically. RESULTS: 161,269 participants were included (55.5% male, mean age 43.2+10.9 years). SD was identified in 3.2% (men: 4.6%, women 1.4%). A significant difference was found between age groups (2.0% in
Source: The British Journal of Dermatology - February 25, 2019 Category: Dermatology Authors: Zander N, Sommer R, Schäfer I, Reinert R, Kirsten N, Zyriax BC, Maul JT, Augustin M Tags: Br J Dermatol Source Type: research

Clinical presentation, therapeutic approach and outcome of primary cutaneous marginal zone B-cell lymphoma presenting as AL amyloidoma of the skin.
This article is protected by copyright. All rights reserved. PMID: 30801660 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 22, 2019 Category: Dermatology Authors: Dangien A, Beylot-Barry M, Battistella M, Ram-Wolff C, Talbot A, Rybojad M, Vergier B, Jachiet M, Bouaziz JD, Arnulf B, Bagot M, de Masson A Tags: Br J Dermatol Source Type: research

Oxytocin Alleviates Cellular Senescence through Oxytocin Receptor-Mediated ERK/Nrf2 Signalling.
CONCLUSIONS: Our findings bring to light OT role as a new clinical strategy for the prevention of skin ageing. This article is protected by copyright. All rights reserved. PMID: 30801661 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 22, 2019 Category: Dermatology Authors: Cho SY, Kim AY, Kim J, Choi DH, Son ED, Shin DW Tags: Br J Dermatol Source Type: research

Open-label, Investigator-Initiated, Single Site Exploratory Trial Evaluating Secukinumab, an anti IL17A monoclonal antibody, for Patients with Moderate-to-Severe Hidradenitis Suppurativa.
This article is protected by copyright. All rights reserved. PMID: 30801662 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 22, 2019 Category: Dermatology Authors: Prussick L, Rothstein B, Joshipura D, Saraiya A, Turkowski Y, Abdat R, Alomran A, Zancanaro P, Kachuk C, Dumont N, Gottlieb AB, Rosmarin D Tags: Br J Dermatol Source Type: research

Digitally reconstructed top-down view images provides intuitive understanding of correlation between dermoscopy and histopathology: A good educational tool.
This article is protected by copyright. All rights reserved. PMID: 30801663 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 22, 2019 Category: Dermatology Authors: Kasuya A, Aoshima M, Fukuchi K, Shimauchi T, Fujiyama T, Tokura Y Tags: Br J Dermatol Source Type: research

Insight into the management of actinic keratosis: a qualitative interview study among general practitioners and dermatologists.
CONCLUSIONS: For AK care to become more standardized and uniform in Dutch primary care, the implementation of guidelines and (continuing) education are needed to address the commonly reported barriers of lack of value, experience and knowledge among GPs. For efficient use of care among dermatologists, shared decision-making tools along with adequate (framing of) patient information may be useful. This article is protected by copyright. All rights reserved. PMID: 30801664 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 22, 2019 Category: Dermatology Authors: Noels EC, Lugtenberg M, van Egmond S, Droger SM, Buis PAJ, Nijsten T, Wakkee M Tags: Br J Dermatol Source Type: research

Post-zygotic mosaicism in a woman with Goltz syndrome mimics segmental angioma serpiginosum.
This article is protected by copyright. All rights reserved. PMID: 30801665 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 22, 2019 Category: Dermatology Authors: Tewari A, Alarcon L, Gordon K, Mansour S, Akhras V Tags: Br J Dermatol Source Type: research

LEKTI domains 6, 7 and 8+9 serve as substrates for transglutaminase 1: implications for targeted therapy of Netherton syndrome.
CONCLUSION: There are specific domains of LEKTI, which are recognized and processed by transglutaminase 1. LEKTI domains D6, D7 and D8+9 contribute to the formation and protection of the cornified envelope. These results impact the development of protein replacement therapy approaches for Netherton syndrome. This article is protected by copyright. All rights reserved. PMID: 30801672 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 22, 2019 Category: Dermatology Authors: Wiegmann H, Valentin F, Tarinski T, Liebau E, Loser K, Traupe H, Oji V Tags: Br J Dermatol Source Type: research

Erythematotelangiectatic rosacea may be associated with a subclinical stage of demodicosis. A case control study.
CONCLUSIONS: ETR may be associated with non-visible Demodex proliferation, possibly corresponding to a subclinical stage of demodicosis. Dermatologists should be aware of this potential association and look for subclinical demodicosis in patients with ETR, so that topical acaricidal treatment can be offered if Demodex density is high. This article is protected by copyright. All rights reserved. PMID: 30801673 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 22, 2019 Category: Dermatology Authors: Forton F, De Maertelaer V Tags: Br J Dermatol Source Type: research