Topical condyloma treatment: comparative evidence for a common problem.
PMID: 32390160 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - May 9, 2020 Category: Dermatology Authors: Doiron P Tags: Br J Dermatol Source Type: research

Epidermolysis bullosa: a 2020 perspective.
PMID: 32390183 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - May 9, 2020 Category: Dermatology Authors: Pope E Tags: Br J Dermatol Source Type: research

Developing a risk prediction model for keratinocyte carcinoma in patients with actinic keratosis.
PMID: 32390191 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - May 9, 2020 Category: Dermatology Authors: Kim Y, Jorgenson E, Asgari MM Tags: Br J Dermatol Source Type: research

Sensitivity to change and Correlation between Autoimmune Bullous Disease Quality of Life questionnaires ABQOL and TABQOL, and objective severity scores.
Abstract The Autoimmune-Bullous-Disease-Quality-of-Life (ABQOL) score is moderately correlated to pemphigus objective-severity-scores (OSS) (with Pemphigus-Disease-Area-Index (PDAI): R =0.42) but is sensitive to change. The Treatment-of-Autoimmune-Bullous Disease-Quality-of-Life (TABQOL) score is weakly correlated to pemphigus OSS (PDAI: R=0.086) and does not change during the course of treatment. PMID: 32374931 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - May 5, 2020 Category: Dermatology Authors: Ferries L, Gillibert A, Duvert-Lehembre S, Corbaux C, Alexandre M, Prost-Squarcioni C, Caux F, Delaporte E, Litrowski N, Boulard C, Murrell DF, Joly P, Hebert V Tags: Br J Dermatol Source Type: research

Natural history of naevi: a two-wave study.
CONCLUSION: Naevus counts increased slightly over time at older ages, but this was dependent on body sites. The overall decrease in naevus counts previously reported in cross-sectional studies has not been confirmed by this longitudinal study. PMID: 32364244 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - May 3, 2020 Category: Dermatology Authors: Ribero S, Zugna D, Spector T, Bataille V Tags: Br J Dermatol Source Type: research

An exploratory, open-label, investigator-initiated study of interleukin-17A (IL-17A) blockade in patients with moderate to severe papulopustular rosacea.
Abstract Currently, few systemic medications are effective for rosacea.1 Recent research has shown elevation of interleukin (IL)-17A in rosacea.2,3 To assess if the IL-17A inhibitor,4, 5 secukinumab, could improve moderate to severe papulopustular rosacea (PPR), an exploratory, open-label, single-arm investigator initiated clinical trial in adults with moderate to severe PPR was performed after Stanford Human Subjects Panel approval. PMID: 32364247 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - May 3, 2020 Category: Dermatology Authors: Kumar AM, Chiou AS, Shih YH, Li S, Chang ALS Tags: Br J Dermatol Source Type: research

Systematic review examining changes over time and variation in the incidence and prevalence of psoriasis by age and gender.
CONCLUSIONS: Studies on changes over time in the occurrence of psoriasis have contributed to a greater appreciation of the increasing burden of the disease. However, further research is required to determine the reason driving the increase in psoriasis prevalence over time. PMID: 32358790 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 30, 2020 Category: Dermatology Authors: Iskandar IYK, Parisi R, Griffiths CEM, Ashcroft DM, Global Psoriasis Atlas Tags: Br J Dermatol Source Type: research

Estimating the global burden of scabies: what else do we need?
Abstract Scabies is one of the most common disorders identified in any estimate of global skin disease prevalence. Furthermore, quantifying its impact on individuals and societies has been problematic. There has been a lack of clear case definitions and laboratory tests. There have been few epidemiological studies, particularly those focusing on low-income countries, variation in prevalence within high-income countries, or estimates of the effect of scabies on health beyond the skin, such as renal disease or mental well-being. Economic studies are also lacking. However, the new strategy of integrating surveillance...
Source: The British Journal of Dermatology - April 30, 2020 Category: Dermatology Authors: Cox V, Fuller LC, Engelman D, Steer A, Hay RJ Tags: Br J Dermatol Source Type: research

A review of studies looking at quality of life and psychological impact in people with photodermatoses - skin diseases triggered by sunlight.
In conclusion, this study confirmed that patients with photodermatoses experience substantial impact on their quality of life and that more research is needed. This is a summary of the study: Quality of life and psychological impact in the photodermatoses: a systematic review. PMID: 32359112 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 30, 2020 Category: Dermatology Authors: Rutter KJ, Ashraf I, Cordingley L, Rhodes LE Tags: Br J Dermatol Source Type: research

Erratum.
Authors: PMID: 32359114 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 30, 2020 Category: Dermatology Tags: Br J Dermatol Source Type: research

Taking aim at identifying treatment targets for psoriasis.
PMID: 32359115 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 30, 2020 Category: Dermatology Authors: Takeshita J Tags: Br J Dermatol Source Type: research

Corrigendum.
Authors: PMID: 32359116 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 30, 2020 Category: Dermatology Tags: Br J Dermatol Source Type: research

Depression as a risk factor for the development of psoriasis: a retrospective cohort study in the United Kingdom.
Abstract Psoriasis is a chronic systemic disease with characteristic papules, plaques and nail changes distributed in highly visible locations. This may contribute to the increased prevalence of depression observed in psoriasis patients compared to the general population.1,2 Interestingly, people with depression without systemic inflammatory disorders have increased levels of inflammatory cytokines including tumor necrosis factor-alpha and Interleukin-6,3 as is seen in psoriasis,4 thereby suggesting a potential for a shared inflammatory pathway. Recent evidence supports a link between depression and the subsequent...
Source: The British Journal of Dermatology - April 29, 2020 Category: Dermatology Authors: Vallerand IA, Lewinson RT, Parsons LM, Lowerison MW, Patten SB, Barnabe C Tags: Br J Dermatol Source Type: research

Cutaneous lesions in a patient with COVID-19: are they related?
yer C Abstract A previously healthy 57-year-old woman presented with fever (39 °C) lasting for 4 days, and dry cough and rash appeared 2 days before. Diffuse fixed erythematous blanching maculopapular lesions were present, asymptomatic over the limbs and trunk, with burning sensation over the palms (a, b). She denied any drug intake, excepting paracetamol for fever. Thorax computed tomography scan was typical of COVID-19; nasopharyngeal swab polymerase chain reaction (PCR) confirmed SARS-CoV-2. Infectious enquiry was otherwise negative. Skin biopsy specimen showed slight spongiosis, basal cell vacuolation...
Source: The British Journal of Dermatology - April 29, 2020 Category: Dermatology Authors: Ahouach B, Harant S, Ullmer A, Martres P, Bégon E, Blum L, Tess O, Bachmeyer C Tags: Br J Dermatol Source Type: research

Classification of the cutaneous manifestations of COVID-19: a rapid prospective nationwide consensus study in Spain with 375 cases.
CONCLUSIONS: We provide a description of the cutaneous manifestations associated with COVID-19 infection. These may help clinicians approach patients with the disease and recognize paucisymptomatic cases. PMID: 32348545 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 28, 2020 Category: Dermatology Authors: Galván Casas C, Català A, Carretero Hernández G, Rodríguez-Jiménez P, Fernández Nieto D, Rodríguez-Villa Lario A, Navarro Fernández I, Ruiz-Villaverde R, Falkenhain D, Llamas Velasco M, García-Gavín J, Baniandrés O, González-Cruz C, Morillas-L Tags: Br J Dermatol Source Type: research

Organic osmolytes increase expression of specific tight junction proteins in skin and alter barrier function in keratinocytes.
CONCLUSIONS: Treatment of skin with organic osmolytes modulates TJ structure and function, which could contribute to the epidermal barrier. This emphasises a role for organic osmolytes beyond the maintenance of intracellular osmolarity. This could be harnessed to enhance topical therapies for diseases characterised by skin barrier dysfunction. PMID: 32348549 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 28, 2020 Category: Dermatology Authors: El-Chami C, Foster AR, Johnson C, Clausen RP, Cornwell P, Haslam IS, Steward MC, Watson REB, Young HS, O'Neill CA Tags: Br J Dermatol Source Type: research

Measurement properties of the Rajka-Langeland severity score in children and adults with atopic dermatitis.
CONCLUSIONS: Rajka-Langeland score showed good construct validity, reliability, internal consistency and responsiveness in adults and children with AD. PMID: 32348552 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 28, 2020 Category: Dermatology Authors: Silverberg JI, Lei D, Yousaf M, Janmohamed SR, Vakharia PP, Chopra R, Chavda R, Gabriel S, Patel KR, Singam V, Kantor R, Hsu DY Tags: Br J Dermatol Source Type: research

Global reporting of cases of COVID-19 in psoriasis and atopic dermatitis: an opportunity to inform care during a pandemic.
udy groups Abstract We wish to bring your attention to the PsoPROTECT (Psoriasis Patient Registry for Outcomes, Therapy and Epidemiology of Covid-19 infecTion) and SECURE-AD (Surveillance Epidemiology of Coronavirus Under Research Exclusion-Atopic Dermatitis) registries; two urgent global initiatives that address an unmet need for delineating the determinants of COVID-19 outcomes in the common cutaneous immune-mediated inflammatory diseases (IMIDs) psoriasis and atopic dermatitis. PMID: 32348554 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 28, 2020 Category: Dermatology Authors: Mahil SK, Yiu ZZN, Mason KJ, Dand N, Coker B, Wall D, Fletcher G, Bosma A, Capon F, Iversen L, Langan SM, Di Meglio P, Musters A, Prieto-Merino D, Tsakok T, Warren RB, Flohr C, Spuls P, Griffiths CEM, Barker J, Irvine AD, Smith CH, Secure-AD, PsoPROTECT s Tags: Br J Dermatol Source Type: research

The impact of COVID-19 pandemic on patients with chronic plaque psoriasis being treated with biologic therapy: the Northern Italy experience.
Abstract The "severe acute respiratory syndrome coronavirus 2" (SARS-CoV-2) has spread over the four continents, causing the respiratory manifestations of Coronavirus disease-19 (COVID-19) and satisfying the epidemiological criteria for a pandemic [1]. As of April 1, 2020, more than one million COVID-19 positive cases have been identified and more than 54,000 deaths have occurred worldwide [2]. In Italy, 110,574 positive cases, 49,285 hospitalized patients and 13,155 deaths out of a population of 60,359,546 inhabitants, have been reported, respectively [3]. The highest number of deaths occurred in the no...
Source: The British Journal of Dermatology - April 27, 2020 Category: Dermatology Authors: Gisondi P, Facheris P, Dapavo P, Piaserico S, Conti A, Naldi L, Cazzaniga S, Malagoli P, Costanzo A Tags: Br J Dermatol Source Type: research

Rising incidence of basal cell carcinoma in women in Iceland: is it sunbed use?
PMID: 32338370 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 26, 2020 Category: Dermatology Authors: Pandeya N Tags: Br J Dermatol Source Type: research

Infinity hair: a new trichoscopic finding for chemotherapy-induced alopecia.
ini G PMID: 32338372 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 26, 2020 Category: Dermatology Authors: Patrì A, Annunziata MC, Cantelli M, Nappa P, Fabbrocini G Tags: Br J Dermatol Source Type: research

CXCL10/IP-10, an early biomarker for late sequelae in DRESS?
un SH PMID: 32338373 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 26, 2020 Category: Dermatology Authors: Bellón T, Kardaun SH Tags: Br J Dermatol Source Type: research

Percentage of scalp-hair loss as a primary endpoint in alopecia areata trials.
PMID: 32338381 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 26, 2020 Category: Dermatology Authors: Blome C Tags: Br J Dermatol Source Type: research

Topical rapamycin combined with calcitriol in treating angiofibromas in tuberous sclerosis complex.
PMID: 32338383 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 26, 2020 Category: Dermatology Authors: Lee CH Tags: Br J Dermatol Source Type: research

Retrospective Cohort Study of Pregnancy Outcomes in Hidradenitis Suppurativa.
The objective of this study was to examine pregnancy complications, pregnancy outcomes, and neonatal outcomes in patients with HS. PMID: 32333790 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 24, 2020 Category: Dermatology Authors: Lyons AB, Peacock A, McKenzie SA, Jacobsen G, Naik HB, Shi VY, Hamzavi IH, Hsiao JL Tags: Br J Dermatol Source Type: research

Protective effects of dietary fish-oil supplementation on skin inflammatory and oxidative stress biomarkers induced by fine particulate air pollution: A pilot randomised, double-blind, placebo-controlled trial.
CONCLUSIONS: This study suggested that dietary fish-oil supplementation may improve biomarkers of skin inflammation and oxidative-stress response to short-term PM2.5 exposure. PMID: 32333793 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 24, 2020 Category: Dermatology Authors: Lin Z, Niu Y, Jiang Y, Chen B, Peng L, Mi T, Huang N, Li W, Xu D, Chen R, Kan H Tags: Br J Dermatol Source Type: research

Clinical forensic dermatology in cases of torture.
Abstract In many European countries the number of asylum seekers has increased in parallel with increasing numbers of migrants and refugees. Recent experiences in providing medical assessment, care and corroborating evidence for people seeking asylum in France motivated us to review the basic principles of forensic dermatology, an essential skill for the attribution of skin lesions to different mechanisms of torture and for proposing appropriate diagnosis. PMID: 32333802 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 24, 2020 Category: Dermatology Authors: Deps P, Collin SM, Aborghetti HP, Charlier P Tags: Br J Dermatol Source Type: research

Epitope competition and neutralizing antidrug antibodies: immune monitoring of antiprogrammed death-1 therapies and lessons learned from natalizumab.
r P Abstract We read with interest the BJD online publication by Gambichler and colleagues1 about a decline of programmed death (PD)-1+ circulating T regulatory cells (Tregs) predicting clinical outcome in anti-PD-1 therapy. The study highlights the potential and importance of immune monitoring in anti-PD-1 checkpoint therapy in malignant melanoma. However, their conclusion about anti-PD-1 antibody treatment effecting a decline of PD-1+ Tregs is misleading. PMID: 32319671 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 21, 2020 Category: Dermatology Authors: Harrer A, Lang R, Kölblinger P Tags: Br J Dermatol Source Type: research

High somatostatin receptor expression and efficacy of somatostatin analogues in patients with metastatic Merkel cell carcinoma.
CONCLUSIONS: In contrast to other high-grade NETs, mMCC tumours appear to frequently express SSTR. SSA can lead to clinically meaningful disease control with minimal side effects. SSTR targeting using SSA or other novel approaches should be explored further for mMCC. PMID: 32320473 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 21, 2020 Category: Dermatology Authors: Akaike T, Qazi J, Anderson A, Behnia FS, Shinohara M, Akaike G, Hippe DS, Thomas H, Takagishi SR, Lachance K, Park SY, Tarabadkar ES, Iyer JG, Blom A, Parvathaneni U, Vesselle H, Nghiem P, Bhatia S Tags: Br J Dermatol Source Type: research

Feasibility and healthcare costs of superpotent topical corticosteroid therapy in bullous pemphigoid: a prospective, observational study in an academic center in France.
The objectives of this study were to determine whether TCS alone were actually used as first-line therapy and could be successfully continued during the first year of treatment in routine practice, and to estimate the related healthcare costs. PMID: 32320476 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 21, 2020 Category: Dermatology Authors: Clapé A, Muller C, Plée J, Viguier M, Vanhaecke C, Bernard P Tags: Br J Dermatol Source Type: research

Sleep disturbance in atopic dermatitis: a case-control study using actigraphy and smartphone-collected questionnaires.
This study aimed to evaluate the sleep of patients with AD and to compare it with that of healthy volunteers using wrist actigraphy and a smartphone application. PMID: 32320479 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 21, 2020 Category: Dermatology Authors: Jachiet M, Bieuvelet S, Argoud AL, Vallée M, Zinaï S, Lejeune FX, Leger D, Bouaziz JD, Elbaz M, Bagot M Tags: Br J Dermatol Source Type: research

Global evidence on occupational sun exposure and keratinocyte cancers: a systematic review.
Abstract Individual studies have suggested that the association between occupational exposure to solar ultraviolet radiation (UVR) and the development of keratinocyte cancers (KC) may only be valid in populations of European ancestry living in certain geographic regions. Comparative global data are scarce and so this review aimed to summarize current evidence on the association between occupational exposure to solar UVR and the development of KC, with a specific focus on geographic location and skin colour. Ovid Medline, PubMed, EMBASE, and Web of Science were searched for potentially relevant records. Extracted d...
Source: The British Journal of Dermatology - April 21, 2020 Category: Dermatology Authors: Loney T, Paulo MS, Modenese A, Gobba F, Tenkate T, Whiteman DC, Green AC, John SM Tags: Br J Dermatol Source Type: research

Partner bereavement can increase the incidence of atopic dermatitis but has no effect on psoriasis.
PMID: 32323301 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 21, 2020 Category: Dermatology Authors: von Kobyletzki LB Tags: Br J Dermatol Source Type: research

Silicone dressings for pressure ulcer prevention.
PMID: 32323310 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 21, 2020 Category: Dermatology Authors: Nixon J Tags: Br J Dermatol Source Type: research

Efficacy and Safety of Ixekizumab in a Phase 3, Randomized, Double-Blind, Placebo-Controlled Study in Paediatric Patients with Moderate-to-Severe Plaque Psoriasis (IXORA-PEDS).
group Abstract BACKGROUND: Plaque psoriasis affects children and adults, but treatment options for paediatric psoriasis are limited. OBJECTIVES: Evaluate the efficacy and safety of ixekizumab (IXE), a high-affinity monoclonal antibody that selectively targets interleukin-17A, for moderate-to-severe paediatric psoriasis. METHODS: In a randomised, double-blind, placebo-controlled, Phase 3 study (IXORA-PEDS), patients (age 6 to
Source: The British Journal of Dermatology - April 20, 2020 Category: Dermatology Authors: Paller AS, Seyger MMB, Magariños GA, Bagel J, Pinter A, Cather J, Keller S, Capriles CR, Lima RG, Gallo G, Little CA, Edson-Heredia E, Li L, Xu W, Papp K, IXORA-PEDS study group Tags: Br J Dermatol Source Type: research

Treatment of hereditary palmoplantar keratoderma: a review by analysis of the literature.
Abstract No specific or curative therapy exists for hereditary Palmoplantar Keratoderma (hPPK) which can profoundly alter patient quality of life, leading sometimes to severe functional impairment and pain. The rarity and the aetiological diversity of this group of disorders can explain the difficulty in comparing the efficacy of available treatments. Our objective was to review the different treatments tried in hPPK patients since 2008, their efficacy and safety, with an evaluation of the various therapeutic modalities that can be used to treat hPPK . We realized a comprehensive review of the literature data publ...
Source: The British Journal of Dermatology - April 19, 2020 Category: Dermatology Authors: Bodemer C, Steijlen P, Hautier JM, O'Toole EA Tags: Br J Dermatol Source Type: research

Mapping the burden of onchocercal skin disease.
Abstract Onchocerciasis is a neglected tropical disease caused by a nematode parasite, Onchocerca volvulus, and transmitted by bites of Simulium blackflies which breed near fast-flowing rivers. In humans thousands of microfilariae (immature worms) migrate to the skin and eyes where they cause pathology. Historically, much research was devoted to the serious effect of blindness, from which the disease earns its alternative name of "river blindness". Mapping the burden of onchocercal skin disease (OSD) was expedited by the development of a clinical classification and grading system which facilitated compar...
Source: The British Journal of Dermatology - April 16, 2020 Category: Dermatology Authors: Murdoch ME Tags: Br J Dermatol Source Type: research

Phototherapeutic approach to dermatological patients during the 2019 Coronavirus pandemic: Real-life Data from the Italian Red Zone.
one A Abstract Since the novel Coronavirus 2019, also known as COVID-19 or SARS CoV-2, crossed the Chinese borders and became pandemic, Italy has rapidly become the country with the highest number of patient deaths as well as confirmed and/or hospitalized patients, after China [1-2]. On March 12th Italy was declared a red-zone and special protocols were enacted to limit the spread of the virus. Although COVID-19 does not have epidermotropism, cutaneous manifestations in Cov-19 positive patients have been reported [3] and departments of dermatology are considered at high risk [4] and were ordered to admit only pati...
Source: The British Journal of Dermatology - April 16, 2020 Category: Dermatology Authors: Pacifico A, Ardigò M, Frascione P, Damiani G, Morrone A Tags: Br J Dermatol Source Type: research

Hidradenitis suppurativa publications are sparse in front-line specialties.
Abstract Hidradenitis suppurativa (HS) is a debilitating inflammatory disease that is understudied, underfunded, and notable for mean diagnostic delay of approximately 7 years. We aimed to characterize annual HS-related publications across medical fields of study caring for HS in order to measure the extent of awareness, education and ongoing research in this area. PMID: 32294228 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 14, 2020 Category: Dermatology Authors: Martins DB, Ayanruoh L, Paul M, Shukla N, Naik HB Tags: Br J Dermatol Source Type: research

Leptin induces interleukin-6 production in keratinocytes via decreased expression of caveolin-1: a possible link between obesity and psoriatic inflammation.
Abstract It has been reported that obesity may be an aggravating factor for psoriasis. However, its pathological mechanism remains elusive. The adipocyte-derived hormone leptin primarily controls energy homeostasis by regulating appetite and modulates immunity. Strikingly, serum leptin levels are elevated in obese patients and positively correlate with body mass index. Additionally, leptin levels also correlate with severity of psoriasis, and knocking out leptin suppresses imiquimod-induced psoriatic inflammation in mice. PMID: 32294231 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 14, 2020 Category: Dermatology Authors: Watanabe Y, Yamaguchi Y, Takamura N, Komitsu N, Aihara M Tags: Br J Dermatol Source Type: research

Cost and Diagnostic Characteristics of Toxicodendron Dermatitis in the United States: A retrospective cross-sectional analysis.
Abstract Toxicodendron dermatitis (TD), or allergic contact dermatitis (ACD) due to poison ivy, oak, and sumac, is the most common cause of ACD in the United States (US). Affecting 10-15 million people every year, TD causes a pruritic, erythematous rash 24-48 hours following skin contact with urushiol, the compound found on poison ivy, oak, and sumac plants responsible for producing an allergic response. PMID: 32294234 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 14, 2020 Category: Dermatology Authors: Zomorodi N, Butt M, Maczuga S, Marks J, Flamm A Tags: Br J Dermatol Source Type: research

High and discordant prevalences of clinical and sonographic enthesitis in patients with hidradenitis suppurativa.
Abstract The prevalence of spondyloarthritis (SpA) reported among patients with hidradenitis suppurativa (HS) ranges from 2.3 to 28.2 %, depending on the diagnostic method used.1 A key feature of SpA and one of the European Spondyloarthropathy Study Group (ESSG) diagnostic criteria for this group of diseases is enthesitis; inflammation at insertion of tendons, ligaments, and capsules. However, pain at an entheseal site is non-specific and does not always indicate inflammation. PMID: 32294241 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 14, 2020 Category: Dermatology Authors: van Straalen KR, Boeren AMP, Wervers K, Prens E, Vis M Tags: Br J Dermatol Source Type: research

Disease characteristics in female and male Patients with Hidradenitis Suppurativa.
en SF Abstract The continuously growing interest in the study of gender medicine in the last years has led to increased awareness of the differences between men and women in the clinical presentation, pathophysiology, management, and prognosis of a wide variety of diseases, including skin diseases. Gender differences in disease characteristics can be influenced by numerous factors, e.g. the effect of sex hormones, anatomy, physiology, and genetics. Variances in skin structure and physiology between the sexes can also contribute to different expressions of certain skin disorders. PMID: 32294242 [PubMed - as su...
Source: The British Journal of Dermatology - April 14, 2020 Category: Dermatology Authors: Jørgensen AR, Ring HC, Yao Y, Thomsen SF Tags: Br J Dermatol Source Type: research

Dapsone therapy for hidradenitis suppurativa.
Abstract Hidradenitis suppurativa (HS) is a chronic inflammatory condition of apocrine gland-bearing skin that is characterised by recurrent painful nodules, abscess and sinus tract formation. Estimates of the prevalence of HS are highly variable, but it is believed to affect around 1% of the population in Europe. Existing treatments for HS include antimicrobial, immunomodulatory and immunosuppressive agents. PMID: 32294243 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 14, 2020 Category: Dermatology Authors: Murray G, Hollywood A, Kirby B, Hughes R Tags: Br J Dermatol Source Type: research

Treatment of severe cutaneous adverse reaction with tocilizumab.
Abstract A 29-year-old Chinese male with recurrent alveolar soft part sarcoma of the tongue metastatic to lung presented with fever and rash (Figure 1a). He underwent glossectomy and adjuvant radiotherapy, complicated by recurrence and abscess with sinus tract formation on the right neck. Current therapy included ipilimumab 3mg/kg and nivolumab 1mg/kg (completed 9 cycles; last dose two days before admission), and cabozantinib 40mg daily (held for six weeks due to sinus tract in the neck). PMID: 32291751 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 13, 2020 Category: Dermatology Authors: Hibler BP, Markova A Tags: Br J Dermatol Source Type: research

Long-term efficacy and safety of brodalumab in psoriasis through 120 weeks and after withdrawal and retreatment: subgroup analysis of a randomised phase 3 trial (AMAGINE-1).
CONCLUSIONS: These findings indicate that brodalumab is efficacious and safe for continuous long-term treatment of psoriasis and support potential for response after discontinuation and retreatment. PMID: 32286683 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 13, 2020 Category: Dermatology Authors: Papp K, Menter A, Leonardi C, Soung J, Weiss S, Pillai R, Jacobson A Tags: Br J Dermatol Source Type: research

Choosing a biologic for psoriasis: is it a sprint or a marathon?
PMID: 32285438 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 12, 2020 Category: Dermatology Authors: Veysey E Tags: Br J Dermatol Source Type: research

Nivolumab-induced toxic epidermal necrolysis with retiform purpura.
PMID: 32281097 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 12, 2020 Category: Dermatology Authors: Basu P, Tong Y, Hinds BR, Schneider JA Tags: Br J Dermatol Source Type: research

What's in? What's out? Updating the British Society for Cutaneous Allergy Facial Series.
CONCLUSION: This audit has highlighted the significant variation in practice that exists amongst patch test centres, despite a recommended facial series. The BSCA facial series has been updated and now contains 24 allergens. Fifteen allergens remain, 11 allergens have been dropped and 9 new allergens have been added. PMID: 32282055 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 12, 2020 Category: Dermatology Authors: Rolls S, Owen E, Bertram CG, Bourke JF, Buckley DA, Chowdhury MMU, Cooper SM, Ghaffar SA, Green CM, Hughes TM, Johnston GA, Reckling CM, Thompson DA, Wakelin SH, Wilkinson M, Stone NM Tags: Br J Dermatol Source Type: research

Partner bereavement and risk of chronic urticaria, alopecia areata and vitiligo: cohort studies in the United Kingdom and Denmark.
In this study, we further investigated whether partner bereavement was associated with urticaria, alopecia areata, or vitiligo. PMID: 32282926 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 12, 2020 Category: Dermatology Authors: Wong AYS, Kjaersgaard A, Frøslev T, Forbes HJ, Mansfield KE, Silverwood RJ, Sørensen HT, Smeeth L, Schmidt SAJ, Langan SM Tags: Br J Dermatol Source Type: research