Predicting keratinocyte carcinoma in patients with actinic keratosis: development and internal validation of a multivariable risk prediction model.
CONCLUSIONS: We showed that the risk of KC in patients with AK can be calculated with the use of four easily assessable predictor variables. Given the c-index, extension of the model with additional, currently unknown predictor variables is desirable. PMID: 31856292 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 19, 2019 Category: Dermatology Authors: Tokez S, Alblas M, Nijsten T, Pardo Cortes LM, Wakkee M Tags: Br J Dermatol Source Type: research

Stevens-Johnson syndrome/toxic epidermal necrolysis: a chronic condition?
PMID: 31853947 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 18, 2019 Category: Dermatology Authors: Lee HY, Creamer D Tags: Br J Dermatol Source Type: research

Response to R. Waldman, M.E. DeWane, S. Brett Sloane: "Letter in Reply - Does IL-4 inhibition play a role in dupilumab-associated conjunctivitis?"
Response to R. Waldman, M.E. DeWane, S. Brett Sloane: "Letter in Reply - Does IL-4 inhibition play a role in dupilumab-associated conjunctivitis?" Br J Dermatol. 2019 Dec 18;: Authors: Ardeleanu M, Shumel B, Rossi AB, Graham NMH Abstract Bakker et al. proposed that interleukin (IL)-13 inhibition-induced goblet cell decline drives dupilumab-associated conjunctivitis in atopic dermatitis (AD).1 In response, Waldman et al.2 suggested that IL-4 inhibition is essential, citing TREBLE, a randomized, 12-week, placebo-controlled, dose-ranging phase 2 trial of lebrikizumab (anti-IL-13 monoclonal anti...
Source: The British Journal of Dermatology - December 18, 2019 Category: Dermatology Authors: Ardeleanu M, Shumel B, Rossi AB, Graham NMH Tags: Br J Dermatol Source Type: research

Image Gallery: Cerebral and subcutaneous sparganosis.
PMID: 31853961 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 18, 2019 Category: Dermatology Authors: Adler BL, Kim GH, Kim DD Tags: Br J Dermatol Source Type: research

Remember to assess the 'whole' patient: a further immune-related adverse event of programmed cell death 1 checkpoint inhibition.
PMID: 31850528 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 18, 2019 Category: Dermatology Authors: Hunter HJA Tags: Br J Dermatol Source Type: research

Image Gallery: Haematogenous metastasis of melanoma mimicking lymphangioma.
eiro M, Bañuls J PMID: 31845311 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 17, 2019 Category: Dermatology Authors: Docampo-Simón A, Sánchez-Pujol MJ, Belinchón-Romero I, Niveiro M, Bañuls J Tags: Br J Dermatol Source Type: research

Hedgehog pathway inhibitors come of age.
PMID: 31849041 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 17, 2019 Category: Dermatology Authors: Fife K Tags: Br J Dermatol Source Type: research

WHO can decrease indoor tanning?
PMID: 31849050 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 17, 2019 Category: Dermatology Authors: Wehner MR Tags: Br J Dermatol Source Type: research

Image Gallery: Palmar and finger vein thrombosis associated with metastatic colorectal cancer.
PMID: 31849052 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 17, 2019 Category: Dermatology Authors: Morgado-Carrasco D, Escoda M Tags: Br J Dermatol Source Type: research

A multinational assessment of work-related productivity loss and indirect costs from a survey of patients with psoriasis.
Abstract BACKGROUND: Total work productivity loss (WPL) and associated indirect costs contribute to the economic burden of psoriasis. OBJECTIVE: To estimate total WPL and related indirect costs, and identify predictors of WPL associated with psoriasis severity in France, Germany, Spain, the UK and Italy (EU5) and the USA. METHODS: Data from the 2015 Adelphi Real World Psoriasis Disease Specific Programme, analysed for absenteeism, presenteeism and total WPL, were quantified (0-100%) from participants that completed the Work Productivity and Activity Impairment (WPAI) instrument. These measures were conve...
Source: The British Journal of Dermatology - December 16, 2019 Category: Dermatology Authors: Villacorta R, Teeple A, Lee S, Fakharzadeh S, Lucas J, McElligott S Tags: Br J Dermatol Source Type: research

Noninferiority of biosimilar MSB110222 to reference adalimumab for chronic plaque psoriasis.
PMID: 31840231 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 15, 2019 Category: Dermatology Authors: Borroni RG, Costanzo A Tags: Br J Dermatol Source Type: research

Patient recall may be of limited use in establishing the clinical relevance of positive patch test reactions (to fragrances).
PMID: 31840234 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 15, 2019 Category: Dermatology Authors: Uter W Tags: Br J Dermatol Source Type: research

Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients: A Critical Appraisal.
Abstract Matta KM et al1 conducted a Phase 1 randomised controlled trial (RCT) to investigate whether four organic UVR filters in four commercially available sunscreens (2 sprays, 1 lotion, 1 cream) were systemically absorbed after four daily applications for four days. The filters were avobenzone (2-3%), oxybenzone (0-6%), octocrylene (2.35-10%) and ecamsule (2%). Plasma concentrations>0.5 ng/mL were reached on day one for all four filters, exceeding the threshold established by the US Food and Drug Administration (FDA). PMID: 31834937 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 13, 2019 Category: Dermatology Authors: Charalambides M, Kibbi N, Young AR Tags: Br J Dermatol Source Type: research

Self-reported naevus density may lead to misclassification of melanoma risk.
Abstract Cutaneous melanoma incidence continues to rise, imposing a sizable burden on health services and society1 . The strongest known risk factor for melanoma is the presence of many melanocytic naevi2 . Naevus prevalence studies use a variety of counting methods from objective counts by dermatologists or research staff, to self-counts. This diversity likely contributes to the variation seen in prevalence estimates3 . Expert counts are more accurate but are labour-intensive and costly. PMID: 31833052 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 12, 2019 Category: Dermatology Authors: Betz-Stablein B, Koh U, Plasmeijer E, Janda M, Aitken JF, Soyer HP, Green AC Tags: Br J Dermatol Source Type: research

Psoriasis Area and Severity Index vs. pharmacokinetics: can monitoring 4-week postinjection ustekinumab concentrations in patients with suboptimal response be clinically relevant?
PMID: 31828758 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 11, 2019 Category: Dermatology Authors: Puig L Tags: Br J Dermatol Source Type: research

Psoriatic epidermis expresses high level of inflammatory mediators and the CDK2/4 cyclin-dependent kinases are involved in the regulation of cell-cycle progression in epidermal cells.
PMID: 31828762 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 11, 2019 Category: Dermatology Authors: Gesser B, Rasmussen MK Tags: Br J Dermatol Source Type: research

Quality of life, Skindex-29, mycosis fungoides/S ézary syndrome.
Quality of life, Skindex-29, mycosis fungoides/Sézary syndrome. Br J Dermatol. 2019 Dec 11;: Authors: Talpur R PMID: 31828764 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 11, 2019 Category: Dermatology Authors: Talpur R Tags: Br J Dermatol Source Type: research

Tissue-specific personalized medicine: the next level of individualized treatment.
PMID: 31828766 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 11, 2019 Category: Dermatology Authors: Ludwig RJ Tags: Br J Dermatol Source Type: research

Role of senescent fibroblasts in the development of idiopathic guttate hypomelanosis.
CONCLUSIONS: Senescent fibroblasts might contribute to the development of IGH through induction of melanocyte senescence and apoptosis in melanocytes via SASP. PMID: 31823346 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 10, 2019 Category: Dermatology Authors: Kim JY, Lee SH, Ahn Y, Lee EJ, Park MY, Hwang S, Almurayshid A, Lim BJ, Oh SH Tags: Br J Dermatol Source Type: research

Revisiting pachyonychia congenita: a case-cohort study of 815 patients.
CONCLUSIONS: Here, we establish phenotype-genotype correlations in the largest cohort of PC patients described to date and reveal novel and clinically useful predictors of disease course and manifestations. PMID: 31823354 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 10, 2019 Category: Dermatology Authors: Samuelov L, Smith FJD, Hansen CD, Sprecher E Tags: Br J Dermatol Source Type: research

Epidemiology of juvenile dermatomyositis in Alsace.
Abstract Juvenile dermatomyositis (JDM) is a rare inflammatory myopathy. 1 Little reliable data is available on epidemiology of JDM.This is an observational, retrospective, multicenter study, using the capture-recapture method to assess incidence and prevalence of JDM in Alsace, a French region with a low migratory rate. Only patients, aged 0 to 16 years, having JDM according to the Bohan and Peter criteria 2 and the EULAR/ACR criteria 3 , were included. Overlap syndromes were excluded. Seven sources were used: hospital dermatologists and pediatricians, their counterparts in private practice, hospital rheumatologi...
Source: The British Journal of Dermatology - December 10, 2019 Category: Dermatology Authors: Moegle C, Severac F, Lipsker D Tags: Br J Dermatol Source Type: research

Enhanced Topical Psoralen-UV-A Therapy via Targeting to Hair Follicles.
Abstract The renewed interest in Psoralen-UV-A (PUVA) therapy driven by impressive recent results in this field encourages the researchers and clinicians to shift the momentum back in its favor.1-3 As far as administration of low-cumulative UV-A doses minimizes the negative risks, the search for efficient modalities decreasing the frequency of sessions may help not to lose such therapeutic option. PMID: 31821544 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 10, 2019 Category: Dermatology Authors: Svenskaya YI, Talnikova EE, Parakhonskiy BV, Tuchin VV, Sukhorukov GB, Gorin DA, Utz SR Tags: Br J Dermatol Source Type: research

Current mysteries of pachyonychia congenita.
PMID: 31814103 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 8, 2019 Category: Dermatology Authors: Leube RE, Schwarz N Tags: Br J Dermatol Source Type: research

KIR3DL2 in cutaneous T-cell lymphoma: from a promising biomarker to a potential therapeutic target.
PMID: 31808144 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 5, 2019 Category: Dermatology Authors: Sun J, Wang Y Tags: Br J Dermatol Source Type: research

The validity of diagnostic and treatment codes for actinic keratosis in electronic health records.
Abstract Actinic keratoses (AK) are among the most common dermatologic diagnoses,1, 2 reported to cost nearly $1 billion yearly in the United States (US).3 Recent AK research has relied on diagnosis and procedure codes to identify AKs in claims and electronic health record (EHR) data.3, 4 However, there has been no investigation of whether these codes accurately identify AKs. Validation of these codes is essential to ensure that using them for research is appropriate and to allow researchers to use single codes (if reliable), rather than more conservative algorithms, simply because a validation has not yet been do...
Source: The British Journal of Dermatology - December 3, 2019 Category: Dermatology Authors: Cohen OG, Margolis DJ, Wehner MR Tags: Br J Dermatol Source Type: research

Making sense of different measures of skin ageing.
PMID: 31792929 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 3, 2019 Category: Dermatology Authors: Law MH Tags: Br J Dermatol Source Type: research

Shedding more light on photoageing.
PMID: 31792943 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 3, 2019 Category: Dermatology Authors: Thornton MJ Tags: Br J Dermatol Source Type: research

Itching for the right treatment.
PMID: 31793672 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 3, 2019 Category: Dermatology Authors: Mate K Tags: Br J Dermatol Source Type: research

The interplay of sun-damage and genetic risk in Australian multiple and single primary melanoma cases and controls.
CONCLUSION: Our cohort demonstrated higher frequencies of previously reported alleles associated with melanoma. MPM melanomas more commonly occur in UV-damaged areas, and these individual are more likely to carry MC1R RHC alleles. Awareness of the interplay of genetic vulnerability with UV damage can stratify risk and guide recommendations for melanoma screening. PMID: 31794051 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 3, 2019 Category: Dermatology Authors: McMeniman EK, Duffy DL, Jagirdar K, Lee KJ, Peach E, McInerney-Leo AM, De'Ambrosis B, Rayner JE, Smithers BM, Soyer HP, Sturm RA Tags: Br J Dermatol Source Type: research

What is the evidence for interactions between filaggrin null mutations and environmental exposures in the aetiology of atopic dermatitis? - A systematic review.
CONCLUSIONS AND RELEVANCE: Evidence on FLG-environment interactions in atopic dermatitis aetiology is limited. However, many of the studies lacked large enough sample sizes to fully assess these interactions. Further research is needed with larger sample sizes and clearly defined exposure assessment. PMID: 31794059 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 3, 2019 Category: Dermatology Authors: Blakeway H, Van-de-Velde V, Allen VB, Kravvas G, Palla L, Page MJ, Flohr C, Weller RB, Irvine AD, McPherson T, Roberts A, Williams HC, Reynolds N, Brown SJ, Paternoster L, Langan SM, UK-TREND Eczema Network Tags: Br J Dermatol Source Type: research

The Impact of Airborne Pollution on Atopic Dermatitis-A Literature Review.
CONCLUSIONS: Airborne pollutants have a detrimental effect on skin barrier integrity and AD symptoms, and appear to pose a multifaceted threat in AD through several parallel mechanisms including oxidative damage, barrier dysfunction, immune stimulation and propagation of the itch-scratch cycle. Future research is needed to elucidate specific mechanisms of pollution-induced epidermal barrier dysfunction and to identify efficacious methods of skin barrier repair and protection against pollutant-driven damage. PMID: 31794065 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 3, 2019 Category: Dermatology Authors: Hendricks AJ, Eichenfield LF, Shi VY Tags: Br J Dermatol Source Type: research

Development and initial testing of a new instrument to measure the experience of eczema control in adults and children: Recap of atopic eczema (RECAP).
Abstract BACKGROUND: Eczema control has been identified as an important outcome by key stakeholders in eczema research (including patients, carers, healthcare professionals, and researchers) but no validated instruments for the domain have been identified. OBJECTIVE: to develop a measurement instrument to capture a patient's perspective of eczema control that is suitable for use in eczema clinical trials. METHODS: Best practice for development of a patient-reported outcome was followed. A mixed-methods approach was used to develop and refine a conceptual framework, generate, refine and select items and t...
Source: The British Journal of Dermatology - December 3, 2019 Category: Dermatology Authors: Howells L, Chalmers JR, Gran S, Ahmed A, Apfelbacher C, Burton T, Howie L, Lawton S, Ridd M, Rogers NK, Sears AV, Spuls P, von Kobyletzki L, Thomas KS Tags: Br J Dermatol Source Type: research

Personalized dosing of ixekizumab for psoriasis.
PMID: 31788787 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 2, 2019 Category: Dermatology Authors: Kim JH Tags: Br J Dermatol Source Type: research

Modifiable risk factors in paediatric atopic dermatitis: is the sun finally shining?
PMID: 31788788 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 2, 2019 Category: Dermatology Authors: Halling-Overgaard AS, Thyssen JP Tags: Br J Dermatol Source Type: research

The clinical relevance of nonblanchable erythema in pressure ulcer prevention.
PMID: 31788790 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 2, 2019 Category: Dermatology Authors: Kottner J Tags: Br J Dermatol Source Type: research

Standing up together to the shame and stigma associated with hidradenitis suppurativa.
PMID: 31789426 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 2, 2019 Category: Dermatology Authors: Kirby JS, Leiphart P Tags: Br J Dermatol Source Type: research

The psychological impact of Stevens-Johnson syndrome and toxic epidermal necrolysis on patients' lives: A critically appraised topic.
DISCUSSION AND RECOMMENDATION FOR CLINICAL CASE: The evidence suggests that SJS and TEN impact psychologically on patients' lives. Education of HCPs, to address their lack of awareness and information on SJS/TEN, should facilitate their capacity to provide information and support to patients, thereby reducing patient anxiety. On discharge, a follow up appointment with relevant HCPs to reduce the possibility of PTSD occurring should be considered. PMID: 31792924 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 2, 2019 Category: Dermatology Authors: O'Reilly P, Kennedy C, Meskell P, Coffey A, Delaunois I, Dore L, Howard S, Ramsay B, Scanlon C, Wilson DM, Whelan B, Ryan S Tags: Br J Dermatol Source Type: research

Image Gallery: Otic lichen planus complicated by tympanic membrane rupture successfully treated with topical 1% tacrolimus.
PMID: 31792931 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 2, 2019 Category: Dermatology Authors: Tran B, Guffey D, Noland M Tags: Br J Dermatol Source Type: research

The changing transcriptome in human skin following in  vivo exposure to erythemal solar-simulated ultraviolet radiation.
The changing transcriptome in human skin following in vivo exposure to erythemal solar-simulated ultraviolet radiation. Br J Dermatol. 2019 Dec 02;: Authors: Hart PH PMID: 31792948 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 2, 2019 Category: Dermatology Authors: Hart PH Tags: Br J Dermatol Source Type: research

Symptomatic mucosal involvement in pachyonychia congenita: the challenges in infants and young children.
CONCLUSION: It is important for dermatologists and otolaryngologists to be aware that symptomatic mucosal involvement, and very rarely laryngeal obstruction, can occur in patients with PC. Usually simple feeding solutions may prevent complications and failure to thrive. PMID: 31777952 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - November 28, 2019 Category: Dermatology Authors: Goldberg I, Mashiah J, Kutz A, Derowe A, Warshauer E, Schwartz ME, Smith F, Sprecher E, Hansen CD Tags: Br J Dermatol Source Type: research

Use of topical Valsartan as a novel treatment of complicated leg ulcers.
Abstract Venous leg ulcers (VLUs) are painful, recalcitrant to therapy and represent a significant burden on quality of patients' life and society (1). Therefore, innovative therapies are needed. Recently, the role of the renin-angiotensin system (RAS) in wound healing has been characterized in animal models (2). Given the availability and excellent safety profile of various RAS modulators, successful repurposing of these drugs to improve healing of chronic ulcers may prove useful in clinical settings. PMID: 31778203 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - November 28, 2019 Category: Dermatology Authors: Hirt PA, Lev-Tov H Tags: Br J Dermatol Source Type: research

Predicting the Long-term Outcomes of Biologics in Psoriasis Patients using Machine Learning.
Abstract Despite the vast amount of data on the efficacy of biologics in psoriasis treatment, therapeutic decision-making is still based on a trial-and-error approach. In a real world setting over 50% of patients needing dose adjustment during therapy and 20-50% of patients experiencing a relapse of the disease requiring a switch to another medication. PMID: 31778205 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - November 28, 2019 Category: Dermatology Authors: Emam S, Du AX, Surmanowicz P, Thomsen SF, Greiner R, Gniadecki R Tags: Br J Dermatol Source Type: research

Partner bereavement and risk of psoriasis and atopic eczema: cohort studies in the United Kingdom and Denmark.
CONCLUSIONS: We found a modest increase in risk of atopic eczema within three years following bereavement, which peaked in the first three months. Acute stress may play a role in triggering onset of new atopic eczema or relapse of atopic eczema previously in remission. We observed no evidence for increased long-term risk of psoriasis and atopic eczema following bereavement. PMID: 31782133 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - November 28, 2019 Category: Dermatology Authors: Wong AYS, Frøslev T, Forbes HJ, Kjaersgaard A, Mulick A, Mansfield K, Silverwood RJ, Sørensen HT, Smeeth L, Schmidt SAJ, Langan SM Tags: Br J Dermatol Source Type: research

Causal inference in melanoma epidemiology using Mendelian randomization.
PMID: 31782141 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - November 28, 2019 Category: Dermatology Authors: Bell KJL Tags: Br J Dermatol Source Type: research

Optimizing audiovisual itch induction: the role of attention and expectancy.
PMID: 31777059 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - November 27, 2019 Category: Dermatology Authors: van Laarhoven AIM, Holle H Tags: Br J Dermatol Source Type: research

Growth profile and anaemia in children with epidermolysis bullosa.
PMID: 31773727 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - November 27, 2019 Category: Dermatology Authors: Laimer M Tags: Br J Dermatol Source Type: research

Atopic dermatitis: economic burden and strategies for high-quality care.
PMID: 31774144 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - November 27, 2019 Category: Dermatology Authors: Ismail N, Bray N Tags: Br J Dermatol Source Type: research

Surgically Resected Hidradenitis Suppurativa: a population-based cost analysis.
Abstract BACKGROUND: Hidradenitis Suppurativa is a painful debilitating skin disorder affecting patients who are typically in their most productive time of life, imposing a significant burden on both the health care system and patients themselves. OBJECTIVE: The main objective of this study was to use a comprehensive, population-based data set to estimate the economic burden of HS surgical management in Canada, and to determine factors associated with higher costs. METHODS: A cohort of HS cases and the cost of sectorial services were obtained from the Institute for Clinical Evaluative Sciences (ICES). Al...
Source: The British Journal of Dermatology - November 27, 2019 Category: Dermatology Authors: Mehdizadeh A, Alavi A, Piguet V, Sibbald G, Vernich L, Marchand M, Rosella L, Hu H, Laporte A, Bashash M Tags: Br J Dermatol Source Type: research

Osteopontin regulatory functions in the hair follicle open a therapeutic approach for hypertrichosis.
PMID: 31774146 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - November 27, 2019 Category: Dermatology Authors: Weiss JM Tags: Br J Dermatol Source Type: research

Light-emitting textiles: an innovative and friendly way to perform photodynamic therapy.
PMID: 31774147 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - November 27, 2019 Category: Dermatology Authors: Gilaberte Y Tags: Br J Dermatol Source Type: research