Impact of COVID-19 pandemic on HIV viremia: a single-center cohort study in northern Italy
CONCLUSIONS: Our efforts to limit the impact of pandemic on our HIV outpatients were effective to ensure HIV continuum of care.PMID:34088307 | PMC:PMC8177258 | DOI:10.1186/s12981-021-00355-x (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - June 5, 2021 Category: Infectious Diseases Authors: Ilaria Izzo Canio Carriero Giulia Gardini Benedetta Fumarola Erika Chiari Francesco Castelli Eugenia Quiros-Roldan Source Type: research

Impact of COVID-19 pandemic on HIV viremia: a single-center cohort study in northern Italy
CONCLUSIONS: Our efforts to limit the impact of pandemic on our HIV outpatients were effective to ensure HIV continuum of care.PMID:34088307 | PMC:PMC8177258 | DOI:10.1186/s12981-021-00355-x (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - June 5, 2021 Category: Infectious Diseases Authors: Ilaria Izzo Canio Carriero Giulia Gardini Benedetta Fumarola Erika Chiari Francesco Castelli Eugenia Quiros-Roldan Source Type: research

Impact of COVID-19 pandemic on HIV viremia: a single-center cohort study in northern Italy
CONCLUSIONS: Our efforts to limit the impact of pandemic on our HIV outpatients were effective to ensure HIV continuum of care.PMID:34088307 | PMC:PMC8177258 | DOI:10.1186/s12981-021-00355-x (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - June 5, 2021 Category: Infectious Diseases Authors: Ilaria Izzo Canio Carriero Giulia Gardini Benedetta Fumarola Erika Chiari Francesco Castelli Eugenia Quiros-Roldan Source Type: research

Impact of COVID-19 pandemic on HIV viremia: a single-center cohort study in northern Italy
CONCLUSIONS: Our efforts to limit the impact of pandemic on our HIV outpatients were effective to ensure HIV continuum of care.PMID:34088307 | DOI:10.1186/s12981-021-00355-x (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - June 5, 2021 Category: Infectious Diseases Authors: Ilaria Izzo Canio Carriero Giulia Gardini Benedetta Fumarola Erika Chiari Francesco Castelli Eugenia Quiros-Roldan Source Type: research

Impact of COVID-19 pandemic on HIV viremia: a single-center cohort study in northern Italy
Brescia Province, northern Italy, was one of the worst epicenters of the COVID-19 pandemic. The division of infectious diseases of ASST (Azienda Socio Sanitaria Territoriale) Spedali Civili Hospital of Brescia... (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - June 4, 2021 Category: Infectious Diseases Authors: Ilaria Izzo, Canio Carriero, Giulia Gardini, Benedetta Fumarola, Erika Chiari, Francesco Castelli and Eugenia Quiros-Roldan Tags: Short Report Source Type: research

Changing trends in lipid profile and biomarkers of renal function and bone metabolism before and after switching from tenofovir disoproxil fumarate to tenofovir alafenamide: a prospective observational study
AIDS Res Ther. 2021 May 27;18(1):30. doi: 10.1186/s12981-021-00354-y.ABSTRACTBACKGROUND: Antiretrovirals, including tenofovir, can suppress human immunodeficiency virus (HIV) infection but cannot completely eradicate it. Patients with HIV infection are administered antiretroviral drugs over a long term; thus, managing consequent adverse drug reactions, such as renal dysfunction and bone mineral loss, is important. Currently, highly sensitive biomarkers that can detect adverse drug reactions early have not been well studied.METHODS: This single-center, prospective, observational study explored changes in the biomarkers of r...
Source: AIDS Research and Therapy - May 28, 2021 Category: Infectious Diseases Authors: Mahoko Ikeda Yoshitaka Wakabayashi Koh Okamoto Shintaro Yanagimoto Shu Okugawa Kyoji Moriya Source Type: research

Changing trends in lipid profile and biomarkers of renal function and bone metabolism before and after switching from tenofovir disoproxil fumarate to tenofovir alafenamide: a prospective observational study
AIDS Res Ther. 2021 May 27;18(1):30. doi: 10.1186/s12981-021-00354-y.ABSTRACTBACKGROUND: Antiretrovirals, including tenofovir, can suppress human immunodeficiency virus (HIV) infection but cannot completely eradicate it. Patients with HIV infection are administered antiretroviral drugs over a long term; thus, managing consequent adverse drug reactions, such as renal dysfunction and bone mineral loss, is important. Currently, highly sensitive biomarkers that can detect adverse drug reactions early have not been well studied.METHODS: This single-center, prospective, observational study explored changes in the biomarkers of r...
Source: AIDS Research and Therapy - May 28, 2021 Category: Infectious Diseases Authors: Mahoko Ikeda Yoshitaka Wakabayashi Koh Okamoto Shintaro Yanagimoto Shu Okugawa Kyoji Moriya Source Type: research

Changing trends in lipid profile and biomarkers of renal function and bone metabolism before and after switching from tenofovir disoproxil fumarate to tenofovir alafenamide: a prospective observational study
AIDS Res Ther. 2021 May 27;18(1):30. doi: 10.1186/s12981-021-00354-y.ABSTRACTBACKGROUND: Antiretrovirals, including tenofovir, can suppress human immunodeficiency virus (HIV) infection but cannot completely eradicate it. Patients with HIV infection are administered antiretroviral drugs over a long term; thus, managing consequent adverse drug reactions, such as renal dysfunction and bone mineral loss, is important. Currently, highly sensitive biomarkers that can detect adverse drug reactions early have not been well studied.METHODS: This single-center, prospective, observational study explored changes in the biomarkers of r...
Source: AIDS Research and Therapy - May 28, 2021 Category: Infectious Diseases Authors: Mahoko Ikeda Yoshitaka Wakabayashi Koh Okamoto Shintaro Yanagimoto Shu Okugawa Kyoji Moriya Source Type: research

Changing trends in lipid profile and biomarkers of renal function and bone metabolism before and after switching from tenofovir disoproxil fumarate to tenofovir alafenamide: a prospective observational study
AIDS Res Ther. 2021 May 27;18(1):30. doi: 10.1186/s12981-021-00354-y.ABSTRACTBACKGROUND: Antiretrovirals, including tenofovir, can suppress human immunodeficiency virus (HIV) infection but cannot completely eradicate it. Patients with HIV infection are administered antiretroviral drugs over a long term; thus, managing consequent adverse drug reactions, such as renal dysfunction and bone mineral loss, is important. Currently, highly sensitive biomarkers that can detect adverse drug reactions early have not been well studied.METHODS: This single-center, prospective, observational study explored changes in the biomarkers of r...
Source: AIDS Research and Therapy - May 28, 2021 Category: Infectious Diseases Authors: Mahoko Ikeda Yoshitaka Wakabayashi Koh Okamoto Shintaro Yanagimoto Shu Okugawa Kyoji Moriya Source Type: research

Changing trends in lipid profile and biomarkers of renal function and bone metabolism before and after switching from tenofovir disoproxil fumarate to tenofovir alafenamide: a prospective observational study
AIDS Res Ther. 2021 May 27;18(1):30. doi: 10.1186/s12981-021-00354-y.ABSTRACTBACKGROUND: Antiretrovirals, including tenofovir, can suppress human immunodeficiency virus (HIV) infection but cannot completely eradicate it. Patients with HIV infection are administered antiretroviral drugs over a long term; thus, managing consequent adverse drug reactions, such as renal dysfunction and bone mineral loss, is important. Currently, highly sensitive biomarkers that can detect adverse drug reactions early have not been well studied.METHODS: This single-center, prospective, observational study explored changes in the biomarkers of r...
Source: AIDS Research and Therapy - May 28, 2021 Category: Infectious Diseases Authors: Mahoko Ikeda Yoshitaka Wakabayashi Koh Okamoto Shintaro Yanagimoto Shu Okugawa Kyoji Moriya Source Type: research

Changing trends in lipid profile and biomarkers of renal function and bone metabolism before and after switching from tenofovir disoproxil fumarate to tenofovir alafenamide: a prospective observational study
AIDS Res Ther. 2021 May 27;18(1):30. doi: 10.1186/s12981-021-00354-y.ABSTRACTBACKGROUND: Antiretrovirals, including tenofovir, can suppress human immunodeficiency virus (HIV) infection but cannot completely eradicate it. Patients with HIV infection are administered antiretroviral drugs over a long term; thus, managing consequent adverse drug reactions, such as renal dysfunction and bone mineral loss, is important. Currently, highly sensitive biomarkers that can detect adverse drug reactions early have not been well studied.METHODS: This single-center, prospective, observational study explored changes in the biomarkers of r...
Source: AIDS Research and Therapy - May 28, 2021 Category: Infectious Diseases Authors: Mahoko Ikeda Yoshitaka Wakabayashi Koh Okamoto Shintaro Yanagimoto Shu Okugawa Kyoji Moriya Source Type: research

Changing trends in lipid profile and biomarkers of renal function and bone metabolism before and after switching from tenofovir disoproxil fumarate to tenofovir alafenamide: a prospective observational study
AIDS Res Ther. 2021 May 27;18(1):30. doi: 10.1186/s12981-021-00354-y.ABSTRACTBACKGROUND: Antiretrovirals, including tenofovir, can suppress human immunodeficiency virus (HIV) infection but cannot completely eradicate it. Patients with HIV infection are administered antiretroviral drugs over a long term; thus, managing consequent adverse drug reactions, such as renal dysfunction and bone mineral loss, is important. Currently, highly sensitive biomarkers that can detect adverse drug reactions early have not been well studied.METHODS: This single-center, prospective, observational study explored changes in the biomarkers of r...
Source: AIDS Research and Therapy - May 28, 2021 Category: Infectious Diseases Authors: Mahoko Ikeda Yoshitaka Wakabayashi Koh Okamoto Shintaro Yanagimoto Shu Okugawa Kyoji Moriya Source Type: research

Changing trends in lipid profile and biomarkers of renal function and bone metabolism before and after switching from tenofovir disoproxil fumarate to tenofovir alafenamide: a prospective observational study
Antiretrovirals, including tenofovir, can suppress human immunodeficiency virus (HIV) infection but cannot completely eradicate it. Patients with HIV infection are administered antiretroviral drugs over a long... (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - May 27, 2021 Category: Infectious Diseases Authors: Mahoko Ikeda, Yoshitaka Wakabayashi, Koh Okamoto, Shintaro Yanagimoto, Shu Okugawa and Kyoji Moriya Tags: Research Source Type: research

Association between depression and HIV treatment outcomes in a US military population with HIV infection
AIDS Res Ther. 2021 May 12;18(1):29. doi: 10.1186/s12981-021-00350-2.ABSTRACTBACKGROUND: Depression is common among HIV-infected individuals and may contribute to suboptimal adherence to antiretroviral therapy (ART) and subsequent inability to attain viral load (VL) suppression. We evaluated associations between depression, self-reported adherence, and longitudinal HIV treatment outcomes in US Military HIV Natural History Study (NHS) participants with and without depression.METHODS: Male NHS participants with available ICD-9 data for mental health diagnoses, Center for Epidemiological Studies Depression (CES-D) measures, a...
Source: AIDS Research and Therapy - May 13, 2021 Category: Infectious Diseases Authors: Brandon Carney Colton Daniels Xiaohe Xu Thankam Sunil Anuradha Ganesan Jason M Blaylock Karl C Kronmann Christina Schofield Tahaniyat Lalani Brian Agan Jason F Okulicz Source Type: research

Association between depression and HIV treatment outcomes in a US military population with HIV infection
AIDS Res Ther. 2021 May 12;18(1):29. doi: 10.1186/s12981-021-00350-2.ABSTRACTBACKGROUND: Depression is common among HIV-infected individuals and may contribute to suboptimal adherence to antiretroviral therapy (ART) and subsequent inability to attain viral load (VL) suppression. We evaluated associations between depression, self-reported adherence, and longitudinal HIV treatment outcomes in US Military HIV Natural History Study (NHS) participants with and without depression.METHODS: Male NHS participants with available ICD-9 data for mental health diagnoses, Center for Epidemiological Studies Depression (CES-D) measures, a...
Source: AIDS Research and Therapy - May 13, 2021 Category: Infectious Diseases Authors: Brandon Carney Colton Daniels Xiaohe Xu Thankam Sunil Anuradha Ganesan Jason M Blaylock Karl C Kronmann Christina Schofield Tahaniyat Lalani Brian Agan Jason F Okulicz Source Type: research

Association between depression and HIV treatment outcomes in a US military population with HIV infection
AIDS Res Ther. 2021 May 12;18(1):29. doi: 10.1186/s12981-021-00350-2.ABSTRACTBACKGROUND: Depression is common among HIV-infected individuals and may contribute to suboptimal adherence to antiretroviral therapy (ART) and subsequent inability to attain viral load (VL) suppression. We evaluated associations between depression, self-reported adherence, and longitudinal HIV treatment outcomes in US Military HIV Natural History Study (NHS) participants with and without depression.METHODS: Male NHS participants with available ICD-9 data for mental health diagnoses, Center for Epidemiological Studies Depression (CES-D) measures, a...
Source: AIDS Research and Therapy - May 13, 2021 Category: Infectious Diseases Authors: Brandon Carney Colton Daniels Xiaohe Xu Thankam Sunil Anuradha Ganesan Jason M Blaylock Karl C Kronmann Christina Schofield Tahaniyat Lalani Brian Agan Jason F Okulicz Source Type: research

Association between depression and HIV treatment outcomes in a US military population with HIV infection
AIDS Res Ther. 2021 May 12;18(1):29. doi: 10.1186/s12981-021-00350-2.ABSTRACTBACKGROUND: Depression is common among HIV-infected individuals and may contribute to suboptimal adherence to antiretroviral therapy (ART) and subsequent inability to attain viral load (VL) suppression. We evaluated associations between depression, self-reported adherence, and longitudinal HIV treatment outcomes in US Military HIV Natural History Study (NHS) participants with and without depression.METHODS: Male NHS participants with available ICD-9 data for mental health diagnoses, Center for Epidemiological Studies Depression (CES-D) measures, a...
Source: AIDS Research and Therapy - May 13, 2021 Category: Infectious Diseases Authors: Brandon Carney Colton Daniels Xiaohe Xu Thankam Sunil Anuradha Ganesan Jason M Blaylock Karl C Kronmann Christina Schofield Tahaniyat Lalani Brian Agan Jason F Okulicz Source Type: research

Association between depression and HIV treatment outcomes in a US military population with HIV infection
AIDS Res Ther. 2021 May 12;18(1):29. doi: 10.1186/s12981-021-00350-2.ABSTRACTBACKGROUND: Depression is common among HIV-infected individuals and may contribute to suboptimal adherence to antiretroviral therapy (ART) and subsequent inability to attain viral load (VL) suppression. We evaluated associations between depression, self-reported adherence, and longitudinal HIV treatment outcomes in US Military HIV Natural History Study (NHS) participants with and without depression.METHODS: Male NHS participants with available ICD-9 data for mental health diagnoses, Center for Epidemiological Studies Depression (CES-D) measures, a...
Source: AIDS Research and Therapy - May 13, 2021 Category: Infectious Diseases Authors: Brandon Carney Colton Daniels Xiaohe Xu Thankam Sunil Anuradha Ganesan Jason M Blaylock Karl C Kronmann Christina Schofield Tahaniyat Lalani Brian Agan Jason F Okulicz Source Type: research

Association between depression and HIV treatment outcomes in a US military population with HIV infection
AIDS Res Ther. 2021 May 12;18(1):29. doi: 10.1186/s12981-021-00350-2.ABSTRACTBACKGROUND: Depression is common among HIV-infected individuals and may contribute to suboptimal adherence to antiretroviral therapy (ART) and subsequent inability to attain viral load (VL) suppression. We evaluated associations between depression, self-reported adherence, and longitudinal HIV treatment outcomes in US Military HIV Natural History Study (NHS) participants with and without depression.METHODS: Male NHS participants with available ICD-9 data for mental health diagnoses, Center for Epidemiological Studies Depression (CES-D) measures, a...
Source: AIDS Research and Therapy - May 13, 2021 Category: Infectious Diseases Authors: Brandon Carney Colton Daniels Xiaohe Xu Thankam Sunil Anuradha Ganesan Jason M Blaylock Karl C Kronmann Christina Schofield Tahaniyat Lalani Brian Agan Jason F Okulicz Source Type: research

Association between depression and HIV treatment outcomes in a US military population with HIV infection
AIDS Res Ther. 2021 May 12;18(1):29. doi: 10.1186/s12981-021-00350-2.ABSTRACTBACKGROUND: Depression is common among HIV-infected individuals and may contribute to suboptimal adherence to antiretroviral therapy (ART) and subsequent inability to attain viral load (VL) suppression. We evaluated associations between depression, self-reported adherence, and longitudinal HIV treatment outcomes in US Military HIV Natural History Study (NHS) participants with and without depression.METHODS: Male NHS participants with available ICD-9 data for mental health diagnoses, Center for Epidemiological Studies Depression (CES-D) measures, a...
Source: AIDS Research and Therapy - May 13, 2021 Category: Infectious Diseases Authors: Brandon Carney Colton Daniels Xiaohe Xu Thankam Sunil Anuradha Ganesan Jason M Blaylock Karl C Kronmann Christina Schofield Tahaniyat Lalani Brian Agan Jason F Okulicz Source Type: research

Association between depression and HIV treatment outcomes in a US military population with HIV infection
AIDS Res Ther. 2021 May 12;18(1):29. doi: 10.1186/s12981-021-00350-2.ABSTRACTBACKGROUND: Depression is common among HIV-infected individuals and may contribute to suboptimal adherence to antiretroviral therapy (ART) and subsequent inability to attain viral load (VL) suppression. We evaluated associations between depression, self-reported adherence, and longitudinal HIV treatment outcomes in US Military HIV Natural History Study (NHS) participants with and without depression.METHODS: Male NHS participants with available ICD-9 data for mental health diagnoses, Center for Epidemiological Studies Depression (CES-D) measures, a...
Source: AIDS Research and Therapy - May 13, 2021 Category: Infectious Diseases Authors: Brandon Carney Colton Daniels Xiaohe Xu Thankam Sunil Anuradha Ganesan Jason M Blaylock Karl C Kronmann Christina Schofield Tahaniyat Lalani Brian Agan Jason F Okulicz Source Type: research

Association between depression and HIV treatment outcomes in a US military population with HIV infection
AIDS Res Ther. 2021 May 12;18(1):29. doi: 10.1186/s12981-021-00350-2.ABSTRACTBACKGROUND: Depression is common among HIV-infected individuals and may contribute to suboptimal adherence to antiretroviral therapy (ART) and subsequent inability to attain viral load (VL) suppression. We evaluated associations between depression, self-reported adherence, and longitudinal HIV treatment outcomes in US Military HIV Natural History Study (NHS) participants with and without depression.METHODS: Male NHS participants with available ICD-9 data for mental health diagnoses, Center for Epidemiological Studies Depression (CES-D) measures, a...
Source: AIDS Research and Therapy - May 13, 2021 Category: Infectious Diseases Authors: Brandon Carney Colton Daniels Xiaohe Xu Thankam Sunil Anuradha Ganesan Jason M Blaylock Karl C Kronmann Christina Schofield Tahaniyat Lalani Brian Agan Jason F Okulicz Source Type: research

Association between depression and HIV treatment outcomes in a US military population with HIV infection
AIDS Res Ther. 2021 May 12;18(1):29. doi: 10.1186/s12981-021-00350-2.ABSTRACTBACKGROUND: Depression is common among HIV-infected individuals and may contribute to suboptimal adherence to antiretroviral therapy (ART) and subsequent inability to attain viral load (VL) suppression. We evaluated associations between depression, self-reported adherence, and longitudinal HIV treatment outcomes in US Military HIV Natural History Study (NHS) participants with and without depression.METHODS: Male NHS participants with available ICD-9 data for mental health diagnoses, Center for Epidemiological Studies Depression (CES-D) measures, a...
Source: AIDS Research and Therapy - May 13, 2021 Category: Infectious Diseases Authors: Brandon Carney Colton Daniels Xiaohe Xu Thankam Sunil Anuradha Ganesan Jason M Blaylock Karl C Kronmann Christina Schofield Tahaniyat Lalani Brian Agan Jason F Okulicz Source Type: research

Association between depression and HIV treatment outcomes in a US military population with HIV infection
AIDS Res Ther. 2021 May 12;18(1):29. doi: 10.1186/s12981-021-00350-2.ABSTRACTBACKGROUND: Depression is common among HIV-infected individuals and may contribute to suboptimal adherence to antiretroviral therapy (ART) and subsequent inability to attain viral load (VL) suppression. We evaluated associations between depression, self-reported adherence, and longitudinal HIV treatment outcomes in US Military HIV Natural History Study (NHS) participants with and without depression.METHODS: Male NHS participants with available ICD-9 data for mental health diagnoses, Center for Epidemiological Studies Depression (CES-D) measures, a...
Source: AIDS Research and Therapy - May 13, 2021 Category: Infectious Diseases Authors: Brandon Carney Colton Daniels Xiaohe Xu Thankam Sunil Anuradha Ganesan Jason M Blaylock Karl C Kronmann Christina Schofield Tahaniyat Lalani Brian Agan Jason F Okulicz Source Type: research

Association between depression and HIV treatment outcomes in a US military population with HIV infection
AIDS Res Ther. 2021 May 12;18(1):29. doi: 10.1186/s12981-021-00350-2.ABSTRACTBACKGROUND: Depression is common among HIV-infected individuals and may contribute to suboptimal adherence to antiretroviral therapy (ART) and subsequent inability to attain viral load (VL) suppression. We evaluated associations between depression, self-reported adherence, and longitudinal HIV treatment outcomes in US Military HIV Natural History Study (NHS) participants with and without depression.METHODS: Male NHS participants with available ICD-9 data for mental health diagnoses, Center for Epidemiological Studies Depression (CES-D) measures, a...
Source: AIDS Research and Therapy - May 13, 2021 Category: Infectious Diseases Authors: Brandon Carney Colton Daniels Xiaohe Xu Thankam Sunil Anuradha Ganesan Jason M Blaylock Karl C Kronmann Christina Schofield Tahaniyat Lalani Brian Agan Jason F Okulicz Source Type: research

Association between depression and HIV treatment outcomes in a US military population with HIV infection
Depression is common among HIV-infected individuals and may contribute to suboptimal adherence to antiretroviral therapy (ART) and subsequent inability to attain viral load (VL) suppression. We evaluated assoc... (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - May 12, 2021 Category: Infectious Diseases Authors: Brandon Carney, Colton Daniels, Xiaohe Xu, Thankam Sunil, Anuradha Ganesan, Jason M. Blaylock, Karl C. Kronmann, Christina Schofield, Tahaniyat Lalani, Brian Agan and Jason F. Okulicz Tags: Short Report Source Type: research

Predictors of mortality rate among adult HIV-positive patients on antiretroviral therapy in Metema Hospital, Northwest Ethiopia: a retrospective follow-up study
This study aimed to assess predictors of mortality rate among adult HIV-positive patients on antiretroviral therapy at Metema Hospital.METHODS: Retrospective follow-up study was employed among ART patients from January 1, 2013, to December 30, 2018. Data were entered in Epi-data 3.1 and exported to STATA 14 for analysis. Kaplan-Meier and Log-Rank test was used to compare survival differences among categories of different variables. In bi-variable analysis p-values
Source: AIDS Research and Therapy - May 6, 2021 Category: Infectious Diseases Authors: Kefale Lejadiss Workie Tilahun Yemanu Birhan Dessie Abebaw Angaw Source Type: research

COVID-19 and HIV infection co-pandemics and their impact: a review of the literature
AIDS Res Ther. 2021 May 5;18(1):28. doi: 10.1186/s12981-021-00335-1.ABSTRACTCoronavirus disease 2019 (COVID-19) was first detected in December 2019. In March 2020, the World Health Organization declared COVID-19 a pandemic. People with underlying medical conditions may be at greater risk of infection and experience complications from COVID-19. COVID-19 has the potential to affect People living with HIV (PLWH) in various ways, including be increased risk of COVID-19 acquisition and interruptions of HIV treatment and care. The purpose of this review article is to evaluate the impact of COVID-19 among PLWH. The contents focus...
Source: AIDS Research and Therapy - May 6, 2021 Category: Infectious Diseases Authors: Sivaporn Gatechompol Anchalee Avihingsanon Opass Putcharoen Kiat Ruxrungtham Daniel R Kuritzkes Source Type: research

Predictors of mortality rate among adult HIV-positive patients on antiretroviral therapy in Metema Hospital, Northwest Ethiopia: a retrospective follow-up study
This study aimed to assess predictors of mortality rate among adult HIV-positive patients on antiretroviral therapy at Metema Hospital.METHODS: Retrospective follow-up study was employed among ART patients from January 1, 2013, to December 30, 2018. Data were entered in Epi-data 3.1 and exported to STATA 14 for analysis. Kaplan-Meier and Log-Rank test was used to compare survival differences among categories of different variables. In bi-variable analysis p-values
Source: AIDS Research and Therapy - May 6, 2021 Category: Infectious Diseases Authors: Kefale Lejadiss Workie Tilahun Yemanu Birhan Dessie Abebaw Angaw Source Type: research

COVID-19 and HIV infection co-pandemics and their impact: a review of the literature
AIDS Res Ther. 2021 May 5;18(1):28. doi: 10.1186/s12981-021-00335-1.ABSTRACTCoronavirus disease 2019 (COVID-19) was first detected in December 2019. In March 2020, the World Health Organization declared COVID-19 a pandemic. People with underlying medical conditions may be at greater risk of infection and experience complications from COVID-19. COVID-19 has the potential to affect People living with HIV (PLWH) in various ways, including be increased risk of COVID-19 acquisition and interruptions of HIV treatment and care. The purpose of this review article is to evaluate the impact of COVID-19 among PLWH. The contents focus...
Source: AIDS Research and Therapy - May 6, 2021 Category: Infectious Diseases Authors: Sivaporn Gatechompol Anchalee Avihingsanon Opass Putcharoen Kiat Ruxrungtham Daniel R Kuritzkes Source Type: research

Predictors of mortality rate among adult HIV-positive patients on antiretroviral therapy in Metema Hospital, Northwest Ethiopia: a retrospective follow-up study
This study aimed to assess predictors of mortality rate among adult HIV-positive patients on antiretroviral therapy at Metema Hospital.METHODS: Retrospective follow-up study was employed among ART patients from January 1, 2013, to December 30, 2018. Data were entered in Epi-data 3.1 and exported to STATA 14 for analysis. Kaplan-Meier and Log-Rank test was used to compare survival differences among categories of different variables. In bi-variable analysis p-values
Source: AIDS Research and Therapy - May 6, 2021 Category: Infectious Diseases Authors: Kefale Lejadiss Workie Tilahun Yemanu Birhan Dessie Abebaw Angaw Source Type: research

COVID-19 and HIV infection co-pandemics and their impact: a review of the literature
AIDS Res Ther. 2021 May 5;18(1):28. doi: 10.1186/s12981-021-00335-1.ABSTRACTCoronavirus disease 2019 (COVID-19) was first detected in December 2019. In March 2020, the World Health Organization declared COVID-19 a pandemic. People with underlying medical conditions may be at greater risk of infection and experience complications from COVID-19. COVID-19 has the potential to affect People living with HIV (PLWH) in various ways, including be increased risk of COVID-19 acquisition and interruptions of HIV treatment and care. The purpose of this review article is to evaluate the impact of COVID-19 among PLWH. The contents focus...
Source: AIDS Research and Therapy - May 6, 2021 Category: Infectious Diseases Authors: Sivaporn Gatechompol Anchalee Avihingsanon Opass Putcharoen Kiat Ruxrungtham Daniel R Kuritzkes Source Type: research

Predictors of mortality rate among adult HIV-positive patients on antiretroviral therapy in Metema Hospital, Northwest Ethiopia: a retrospective follow-up study
This study aimed to assess predictors of mortality rate among adult HIV-positive patients on antiretroviral therapy at Metema Hospital.METHODS: Retrospective follow-up study was employed among ART patients from January 1, 2013, to December 30, 2018. Data were entered in Epi-data 3.1 and exported to STATA 14 for analysis. Kaplan-Meier and Log-Rank test was used to compare survival differences among categories of different variables. In bi-variable analysis p-values
Source: AIDS Research and Therapy - May 6, 2021 Category: Infectious Diseases Authors: Kefale Lejadiss Workie Tilahun Yemanu Birhan Dessie Abebaw Angaw Source Type: research

COVID-19 and HIV infection co-pandemics and their impact: a review of the literature
AIDS Res Ther. 2021 May 5;18(1):28. doi: 10.1186/s12981-021-00335-1.ABSTRACTCoronavirus disease 2019 (COVID-19) was first detected in December 2019. In March 2020, the World Health Organization declared COVID-19 a pandemic. People with underlying medical conditions may be at greater risk of infection and experience complications from COVID-19. COVID-19 has the potential to affect People living with HIV (PLWH) in various ways, including be increased risk of COVID-19 acquisition and interruptions of HIV treatment and care. The purpose of this review article is to evaluate the impact of COVID-19 among PLWH. The contents focus...
Source: AIDS Research and Therapy - May 6, 2021 Category: Infectious Diseases Authors: Sivaporn Gatechompol Anchalee Avihingsanon Opass Putcharoen Kiat Ruxrungtham Daniel R Kuritzkes Source Type: research

Predictors of mortality rate among adult HIV-positive patients on antiretroviral therapy in Metema Hospital, Northwest Ethiopia: a retrospective follow-up study
This study aimed to assess predictors of mortality rate among adult HIV-positive patients on antiretroviral therapy at Metema Hospital.METHODS: Retrospective follow-up study was employed among ART patients from January 1, 2013, to December 30, 2018. Data were entered in Epi-data 3.1 and exported to STATA 14 for analysis. Kaplan-Meier and Log-Rank test was used to compare survival differences among categories of different variables. In bi-variable analysis p-values
Source: AIDS Research and Therapy - May 6, 2021 Category: Infectious Diseases Authors: Kefale Lejadiss Workie Tilahun Yemanu Birhan Dessie Abebaw Angaw Source Type: research

COVID-19 and HIV infection co-pandemics and their impact: a review of the literature
AIDS Res Ther. 2021 May 5;18(1):28. doi: 10.1186/s12981-021-00335-1.ABSTRACTCoronavirus disease 2019 (COVID-19) was first detected in December 2019. In March 2020, the World Health Organization declared COVID-19 a pandemic. People with underlying medical conditions may be at greater risk of infection and experience complications from COVID-19. COVID-19 has the potential to affect People living with HIV (PLWH) in various ways, including be increased risk of COVID-19 acquisition and interruptions of HIV treatment and care. The purpose of this review article is to evaluate the impact of COVID-19 among PLWH. The contents focus...
Source: AIDS Research and Therapy - May 6, 2021 Category: Infectious Diseases Authors: Sivaporn Gatechompol Anchalee Avihingsanon Opass Putcharoen Kiat Ruxrungtham Daniel R Kuritzkes Source Type: research

Predictors of mortality rate among adult HIV-positive patients on antiretroviral therapy in Metema Hospital, Northwest Ethiopia: a retrospective follow-up study
Globally Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome (HIV/AIDS) is an ongoing public health issue associated with high morbidity and mortality. Efforts have been made to reduce HIV/AIDS-re... (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - May 5, 2021 Category: Infectious Diseases Authors: Kefale Lejadiss Workie, Tilahun Yemanu Birhan and Dessie Abebaw Angaw Tags: Research Source Type: research

COVID-19 and HIV infection co-pandemics and their impact: a review of the literature
Coronavirus disease 2019 (COVID-19) was first detected in December 2019. In March 2020, the World Health Organization declared COVID-19 a pandemic. People with underlying medical conditions may be at greater r... (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - May 5, 2021 Category: Infectious Diseases Authors: Sivaporn Gatechompol, Anchalee Avihingsanon, Opass Putcharoen, Kiat Ruxrungtham and Daniel R. Kuritzkes Tags: Review Source Type: research

Virologic outcomes of switching to dolutegravir functional mono- or dual therapy with a non-cytosine nucleoside analog: a retrospective study of treatment-experienced, patients living with HIV
AIDS Res Ther. 2021 May 3;18(1):26. doi: 10.1186/s12981-021-00352-0.ABSTRACTBACKGROUND: Dolutegravir (DTG) monotherapy results in virologic failure and the development of DTG resistance. Here, we evaluated virologic outcomes of patients switched to DTG functional mono- or dual therapy with a non-cytosine nucleoside analog (NA).METHODS: This retrospective, single center study included treatment-experienced patients switched to regimens containing ≥ 2 antiretrovirals between 8/13/13-11/22/14 who were later found to be on DTG functional mono- or dual therapy with a non-cytosine NA based on historical genotypes. Eligible pa...
Source: AIDS Research and Therapy - May 4, 2021 Category: Infectious Diseases Authors: Charlotte-Paige Rolle Vu Nguyen Federico Hinestrosa Edwin DeJesus Source Type: research

Virologic outcomes of switching to dolutegravir functional mono- or dual therapy with a non-cytosine nucleoside analog: a retrospective study of treatment-experienced, patients living with HIV
AIDS Res Ther. 2021 May 3;18(1):26. doi: 10.1186/s12981-021-00352-0.ABSTRACTBACKGROUND: Dolutegravir (DTG) monotherapy results in virologic failure and the development of DTG resistance. Here, we evaluated virologic outcomes of patients switched to DTG functional mono- or dual therapy with a non-cytosine nucleoside analog (NA).METHODS: This retrospective, single center study included treatment-experienced patients switched to regimens containing ≥ 2 antiretrovirals between 8/13/13-11/22/14 who were later found to be on DTG functional mono- or dual therapy with a non-cytosine NA based on historical genotypes. Eligible pa...
Source: AIDS Research and Therapy - May 4, 2021 Category: Infectious Diseases Authors: Charlotte-Paige Rolle Vu Nguyen Federico Hinestrosa Edwin DeJesus Source Type: research

Virologic outcomes of switching to dolutegravir functional mono- or dual therapy with a non-cytosine nucleoside analog: a retrospective study of treatment-experienced, patients living with HIV
AIDS Res Ther. 2021 May 3;18(1):26. doi: 10.1186/s12981-021-00352-0.ABSTRACTBACKGROUND: Dolutegravir (DTG) monotherapy results in virologic failure and the development of DTG resistance. Here, we evaluated virologic outcomes of patients switched to DTG functional mono- or dual therapy with a non-cytosine nucleoside analog (NA).METHODS: This retrospective, single center study included treatment-experienced patients switched to regimens containing ≥ 2 antiretrovirals between 8/13/13-11/22/14 who were later found to be on DTG functional mono- or dual therapy with a non-cytosine NA based on historical genotypes. Eligible pa...
Source: AIDS Research and Therapy - May 4, 2021 Category: Infectious Diseases Authors: Charlotte-Paige Rolle Vu Nguyen Federico Hinestrosa Edwin DeJesus Source Type: research

Virologic outcomes of switching to dolutegravir functional mono- or dual therapy with a non-cytosine nucleoside analog: a retrospective study of treatment-experienced, patients living with HIV
Dolutegravir (DTG) monotherapy results in virologic failure and the development of DTG resistance. Here, we evaluated virologic outcomes of patients switched to DTG functional mono- or dual therapy with a non-... (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - May 3, 2021 Category: Infectious Diseases Authors: Charlotte-Paige Rolle, Vu Nguyen, Federico Hinestrosa and Edwin DeJesus Tags: Research Source Type: research

Integrase inhibitors versus efavirenz combination antiretroviral therapies for TB/HIV coinfection: a meta-analysis of randomized controlled trials
CONCLUSION: This meta-analysis demonstrates similar efficacy and safety of INIs-based ART compared with EFV-based ART. This finding supports INIs-based ART as a first-line treatment in TB/HIV patients. The conclusions presented here still await further validation owing to insufficient data.PMID:33933131 | DOI:10.1186/s12981-021-00348-w (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - May 2, 2021 Category: Infectious Diseases Authors: Yuanlu Shu Ziwei Deng Hongqiang Wang Yi Chen Lijialong Yuan Ye Deng Xiaojun Tu Xiang Zhao Zhihua Shi Minjiang Huang Chengfeng Qiu Source Type: research

Integrase inhibitors versus efavirenz combination antiretroviral therapies for TB/HIV coinfection: a meta-analysis of randomized controlled trials
CONCLUSION: This meta-analysis demonstrates similar efficacy and safety of INIs-based ART compared with EFV-based ART. This finding supports INIs-based ART as a first-line treatment in TB/HIV patients. The conclusions presented here still await further validation owing to insufficient data.PMID:33933131 | DOI:10.1186/s12981-021-00348-w (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - May 2, 2021 Category: Infectious Diseases Authors: Yuanlu Shu Ziwei Deng Hongqiang Wang Yi Chen Lijialong Yuan Ye Deng Xiaojun Tu Xiang Zhao Zhihua Shi Minjiang Huang Chengfeng Qiu Source Type: research

Integrase inhibitors versus efavirenz combination antiretroviral therapies for TB/HIV coinfection: a meta-analysis of randomized controlled trials
Integrase inhibitors (INIs)-based antiretroviral therapies (ART) are more recommended than efavirenz (EFV)-based ART for people living with HIV/AIDS (PLWHA). Yet, the advantage of integrase inhibitors in treat... (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - May 1, 2021 Category: Infectious Diseases Authors: Yuanlu Shu, Ziwei Deng, Hongqiang Wang, Yi Chen, Lijialong Yuan, Ye Deng, Xiaojun Tu, Xiang Zhao, Zhihua Shi, Minjiang Huang and Chengfeng Qiu Tags: Review Source Type: research

Determinants of gender disparities in scaling up the first 90 towards the UNAIDS 90-90-90 targets in South Africa: findings from the 2017 household-based national cross-sectional survey
This study examined determinants of the first 90 target among females and males in order to inform strategies aimed at improving the HIV cascade in South Africa.METHODS: The data used in the analysis were obtained from a 2017 household-based cross-sectional nationally representative survey conducted using a multi-stage stratified cluster random sampling design. A series of hierarchical multiple logistic regression models were fitted to identify the determinants of the first 90 target by gender.RESULTS: Overall, 84.8% of HIV-positive individuals aged 15 years and older were aware of their HIV status. Females were significan...
Source: AIDS Research and Therapy - April 29, 2021 Category: Infectious Diseases Authors: S Jooste M Mabaso M Taylor A North Y L Shean L C Simbayi Source Type: research

Determinants of gender disparities in scaling up the first 90 towards the UNAIDS 90-90-90 targets in South Africa: findings from the 2017 household-based national cross-sectional survey
This study examined determinants of the first 90 target among females and males in order to inform strategies aimed at improving the HIV cascade in South Africa.METHODS: The data used in the analysis were obtained from a 2017 household-based cross-sectional nationally representative survey conducted using a multi-stage stratified cluster random sampling design. A series of hierarchical multiple logistic regression models were fitted to identify the determinants of the first 90 target by gender.RESULTS: Overall, 84.8% of HIV-positive individuals aged 15 years and older were aware of their HIV status. Females were significan...
Source: AIDS Research and Therapy - April 29, 2021 Category: Infectious Diseases Authors: S Jooste M Mabaso M Taylor A North Y L Shean L C Simbayi Source Type: research

Determinants of gender disparities in scaling up the first 90 towards the UNAIDS 90-90-90 targets in South Africa: findings from the 2017 household-based national cross-sectional survey
This study examined determinants of the first 90 target among females and males in order to inform strategies aimed at improving the HIV cascade in South Africa.METHODS: The data used in the analysis were obtained from a 2017 household-based cross-sectional nationally representative survey conducted using a multi-stage stratified cluster random sampling design. A series of hierarchical multiple logistic regression models were fitted to identify the determinants of the first 90 target by gender.RESULTS: Overall, 84.8% of HIV-positive individuals aged 15 years and older were aware of their HIV status. Females were significan...
Source: AIDS Research and Therapy - April 29, 2021 Category: Infectious Diseases Authors: S Jooste M Mabaso M Taylor A North Y L Shean L C Simbayi Source Type: research

The prevalence of depression among adolescent with HIV/AIDS: a systematic review and meta-analysis
CONCLUSION: Our study shows that a significant proportion of adolescents with HIV had depression, indicating the imperativeness of intervention strategies to alleviate the suffering and possibly reduce the probable negative ramifications.PMID:33906698 | PMC:PMC8077927 | DOI:10.1186/s12981-021-00351-1 (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - April 28, 2021 Category: Infectious Diseases Authors: Getinet Ayano Sileshi Demelash Mebratu Abraha Light Tsegay Source Type: research

The prevalence of depression among adolescent with HIV/AIDS: a systematic review and meta-analysis
CONCLUSION: Our study shows that a significant proportion of adolescents with HIV had depression, indicating the imperativeness of intervention strategies to alleviate the suffering and possibly reduce the probable negative ramifications.PMID:33906698 | DOI:10.1186/s12981-021-00351-1 (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - April 28, 2021 Category: Infectious Diseases Authors: Getinet Ayano Sileshi Demelash Mebratu Abraha Light Tsegay Source Type: research