Clinical course and disease burden of patients with generalized pustular psoriasis in Portugal: a multicenter retrospective cohort study
CONCLUSIONS: Our study demonstrates that GPP is a chronic, debilitating condition associated with systemic involvement, frequent flares, and hospitalizations, despite receiving multiple systemic treatments. Improved disease awareness and new treatments are needed to improve patient care and decrease the burden of the disease.PMID:38684228 | DOI:10.1080/09546634.2024.2345728 (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - April 29, 2024 Category: Dermatology Authors: Tiago Torres Joana Antunes Ana Brasileiro Jo ão Alves Diana Bernardo Jos é Ramos Diogo Sousa Cristina Castro Ana Gusm ão Palmeiro Andr é Aparício Martins Joana Fazendeiro Matos B árbara Vieira Granja Pedro Ponte Gabriela Marques Pinto Paula Quirino Source Type: research
Statement of retraction: evidence-based clinical practice guidelines for the management of psoriasis: systematic review, critical appraisal, and quality assessment with the AGREE II instrument
J Dermatolog Treat. 2024 Dec;35(1):2334685. doi: 10.1080/09546634.2024.2334685. Epub 2024 Apr 29.NO ABSTRACTPMID:38684214 | DOI:10.1080/09546634.2024.2334685 (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - April 29, 2024 Category: Dermatology Source Type: research
Novel foam dressing with through holes and negative pressure wound therapy with instillation and dwell time: a retrospective cohort study
CONCLUSION: ROCF-CC dressings were a useful tool in assisting wound bed preparation and reducing time to skin graft closure in this series of complex VLUs.PMID:38684120 (Source: Wounds)
Source: Wounds - April 29, 2024 Category: General Medicine Authors: Carlotta Scarpa Martina Grigatti Sandro Rizzato Alberto Crema Vincenzo Vindigni Franco Bassetto Source Type: research
Use of dynamic tissue system adhesive skin closure device and multi-tissue platform porcine xenograft to achieve primary closure after wide local excision of a melanoma
CONCLUSION: The results of this patient's case indicate that DTS adhesive skin closure device should be considered as an additional option for the closure of large defects following wide local excision in the management of melanoma.PMID:38684122 (Source: Wounds)
Source: Wounds - April 29, 2024 Category: General Medicine Authors: Jad F Zeitouni Reagan Collins Patricia Arledge Yana Puckett Catherine F Ronaghan Source Type: research
Cutaneous Crohn disease presenting as "knife-edged" ulcers: a case report
CONCLUSIONS: This case supports the inclusion of CCD in the differential diagnosis in patients with knife-edged granulomatous skin lesions in intertriginous locations. This clinical condition may present in the setting of no or limited GI symptoms. The management of CCD and a proposed treatment algorithm are also presented.PMID:38684123 (Source: Wounds)
Source: Wounds - April 29, 2024 Category: General Medicine Authors: Melissa A Nickles Saman S Karimi Heidi Kurn Marylee Braniecki Anne Polick Itishree Trivedi Nadera Sweiss Igor A Altman Source Type: research
The Observatoire en Ville des Plaies ExSudatives (VIPES) study: insight into the patient characteristics, epidemiology, previous management, and features of wounds treated in the French community setting
CONCLUSIONS: The VIPES study highlights that wounds can be complex and that community care practices in France warrant improvement. Practical and up-to-date wound management recommendations are needed.PMID:38684125 (Source: Wounds)
Source: Wounds - April 29, 2024 Category: General Medicine Authors: Pascal Vasseur Nayla Ayoub Christine Juhel Romain Schueller Adoraci ón Pegalajar-Jurado Florence Armstrong Source Type: research
Lactic Acid Chemical Peeling in Skin Disorders
Clin Cosmet Investig Dermatol. 2024 Apr 23;17:901-909. doi: 10.2147/CCID.S455700. eCollection 2024.ABSTRACTLactic acid is the most widely occurring natural organic acid in nature. It not only exhibits mild and safe properties but also possesses multiple physiological activities, such as antibacterial effects, immune regulation, and promotion of wound healing, making it one of the most popular chemical peeling agents. Chemical peels are commonly used in the field of aesthetic dermatology as a non-invasive therapeutic approach. This research aims to provide valuable references for clinical dermatologists by summarizing the c...
Source: Clinical, Cosmetic and Investigational Dermatology - April 29, 2024 Category: Dermatology Authors: Xiaoyue Feng Jianli Shang Zhengping Gu Xingyi Luo Yong Chen Youting Liu Source Type: research
The first molecular investigation of Besnoitia besnoiti infections among cattle in Mosul, Iraq
CONCLUSIONS: Findings from this study will serve as baseline data in the epidemiology, prevention, and control of the protozoan among cattle in Iraq.PMID:38683464 | DOI:10.1007/s11033-024-09377-w (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - April 29, 2024 Category: Molecular Biology Authors: Wasan Amjad Alobaidii Donea Abdulrazak Abdullah Yahya Natiq Mohammed Alkatab Shahad Abbas Ali Shola David Ola-Fadunsin Fufa Ido Gimba Source Type: research
Novel investigational drugs for alopecia areata and future perspectives
Expert Opin Investig Drugs. 2024 Apr 29. doi: 10.1080/13543784.2024.2348062. Online ahead of print.ABSTRACTINTRODUCTION: Alopecia areata (AA) is an immune-mediated disease that causes non-scarring hair loss. While acute, solitary patches often spontaneously remit, developing secondary patches or failure of the disease to resolve within 6-12 months predicts a poor prognosis, with an increased risk of alopecia totalis or universalis. Chronic AA increases the risk of depression and suicidality and reduces quality of life. Treatment options for chronic or acute diffuse AA were previously limited to corticosteroids and traditio...
Source: Expert Opinion on Investigational Drugs - April 29, 2024 Category: Drugs & Pharmacology Authors: Ivana Chim Ragini Ghiya Rodney D Sinclair Samantha Eisman Source Type: research
Silymarin inhibits dermal gelatinolytic activity and reduces cutaneous inflammation
Nat Prod Res. 2024 Apr 29:1-12. doi: 10.1080/14786419.2024.2347452. Online ahead of print.ABSTRACTMilk thistle (Silybum marianum) is well-known for its antioxidant activity due to the presence of silymarin. Albeit some studies show a potential for skin inflammation, its activity against dermal MMP-9 and MMP-2 remains to be studied. Silymarin isolated from an S. marianum herbal extract was tested for gelatinase inhibition in the presence of isolated MMP-9 and in dermal adenocarcinome HaCaT cells. Silymarin was then further tested in vivo, using a cutaneous inflammation mice model mediated by reactive oxygen species. Silymar...
Source: Natural Product Research - April 29, 2024 Category: Biochemistry Authors: Joana Mota Catarina Faria-Silva Ana Resendes Maria Isabel Santos Manuela Colla Carvalheiro Ana Lima Sandra Sim ões Source Type: research
Safety Profile of Upadacitinib up to 5 Years in Psoriatic Arthritis, Ankylosing Spondylitis, and Non-radiographic Axial Spondyloarthritis: An Integrated Analysis of Clinical Trials
CONCLUSION: Higher rates of serious infection, HZ, lymphopenia, and NMSC were observed with upadacitinib versus adalimumab in PsA; slightly elevated rates for most of these TEAEs were seen with upadacitinib in PsA versus axSpA. Upadacitinib 15 mg demonstrated a generally consistent safety profile across disease states with no new safety signals identified.TRIAL REGISTRATION: SELECT-AXIS 1: NCT03178487; SELECT-AXIS 2: NCT04169373; SELECT-PsA 1: NCT03104400; SELECT-PsA 2: NCT03104374.PMID:38683479 | DOI:10.1007/s40744-024-00671-4 (Source: Herpes)
Source: Herpes - April 29, 2024 Category: Infectious Diseases Authors: Gerd R Burmester Jayne Stigler Andrea Rubbert-Roth Yoshiya Tanaka Valderilio F Azevedo Derek Coombs Ivan Lagunes Ralph Lippe Peter Wung Lianne S Gensler Source Type: research
A systematic review and meta-analysis of herpes zoster occurrence/recurrence after COVID-19 infection and vaccination
J Med Virol. 2024 May;96(5):e29629. doi: 10.1002/jmv.29629.ABSTRACTTo inform surveillance, prevention, and management strategies for the varicella zoster virus (VZV) during the COVID-19 pandemic, this study aimed to evaluate the risk of herpes zoster (HZ) occurrence/recurrence following COVID-19 infection and vaccination. A comprehensive search across seven databases was conducted up to January 31, 2024, to identify studies relevant to the occurrence of HZ following COVID-19 infection and vaccination. The meta-analysis included five studies on postinfection HZ and 13 studies on postvaccination HZ. Patients infected with CO...
Source: Herpes - April 29, 2024 Category: Infectious Diseases Authors: Fengge Wang Yidan Gao Abram L Wagner Yihan Lu Source Type: research
Ethnopharmacological uses of fauna among the people of central Punjab, Pakistan
This study focuses on investigating the utilization of animal-based traditional medicine by the people of Pakistan, specifically in the Gujranwala area.METHODS: Data collection took place from January to September 2019 through interviews with local communities. Ethnomedicinal applications of animal products were analyzed using several indices, including Relative Frequency of Citation (RFC), Relative Popularity Level (RPL), Folk Use Value (FL), and Relative Occurrence Percentage (ROP).RESULTS: The study identified the use of different body parts of 54 species of animals in treating various diseases and health issues. These ...
Source: Herpes - April 29, 2024 Category: Infectious Diseases Authors: Abdul Majid Khan Muhammad Altaf Tanveer Hussain M Haroon Hamed Umaira Safdar Amina Ayub Zaibun-Nisa Memon Adnan Hafiz Sana Ashraf Muhammad Shoaib Amjad Muhammad Majeed Musheerul Hassan Rainer W Bussmann Arshad Mahmood Abbasi Mohamed Al-Yafrsi Hosam O Elan Source Type: research
Skin reactions associated with glucose monitoring devices
Ir Med J. 2024 Apr 25;117(4):942.NO ABSTRACTPMID:38682671 (Source: Ir Med J)
Source: Ir Med J - April 29, 2024 Category: General Medicine Authors: P Finnegan E Porter J Bourke Source Type: research
Human herpesvirus type 6 in patients with systemic lupus erythematosus
CONCLUSION: Although patients with SLE had a higher prevalence of HHV-6 compared with healthy people, there is no strong link between HHV-6 infection and SLE. Future research is necessary because this data does not support the hypothesis that human herpesvirus 6 plays a role in the pathogenesis of SLE.PMID:38682068 | PMC:PMC11055447 | DOI:10.18502/ijm.v16i1.14883 (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - April 29, 2024 Category: Microbiology Authors: Mohammad Shayestehpour Elnaz Vatani Batool Zamani Ahmad Piroozmand Shaghayegh Yazdani Kamal Esalatmanesh Zahrasadat Fateminasab Source Type: research
