Lymphedema: A Practical Approach and Clinical Update.
Authors: Bittar S, Simman R, Lurie F Abstract The lymphatic system is arguably the most neglected bodily system. As a result, its contribution to human health and disease is not well understood. In this review, the clinical approaches based on new knowledge and developments of the lymphatic system are covered. The lymphatic system has 3 major functions: (1) the preservation of fluid balance; (2) a nutritional function, as intestinal lymphatics are responsible for fat absorption; and (3) host defense. Lymph vessels return the capillary ultrafiltrate and escaped plasma proteins from most tissues back, ultimately, to ...
Source: Wounds - March 14, 2020 Category: General Medicine Tags: Wounds Source Type: research

Topical Oxygen Therapy Shifts Microbiome Dynamics in Chronic Diabetic Foot Ulcers.
CONCLUSIONS: Although the sample size was small, this study suggests topical oxygen therapy may have the ability to encourage the growth of aerobic members of the wound microbiome and be an effective alternative to antibiotics in this area. PMID: 32163040 [PubMed - in process] (Source: Wounds)
Source: Wounds - March 14, 2020 Category: General Medicine Tags: Wounds Source Type: research

Bacterial Species and Load Increase During Negative Pressure Wound Therapy: A Prospective Cohort Study.
CONCLUSIONS: The number of S aureus strains and overall bacterial load increased during NPWT, and the incidence of infection remained the same. Further studies should be conducted to determine whether the increase in bacterial load influences other wound outcome parameters. PMID: 32163041 [PubMed - in process] (Source: Wounds)
Source: Wounds - March 14, 2020 Category: General Medicine Tags: Wounds Source Type: research

Laser Therapy Induces Increased Viability and Proliferation in Isolated Fibroblast Cells.
CONCLUSIONS: The findings of this study show LT increased fibroblast cell proliferation, depending on the power output level of the laser and number of applications. In addition to the proliferation and mitotic activity of the fibroblast cells, the results demonstrate that LT could increase wound healing after oral surgery and periodontal treatments. PMID: 32163042 [PubMed - in process] (Source: Wounds)
Source: Wounds - March 14, 2020 Category: General Medicine Tags: Wounds Source Type: research

Intraabdominal Lavage of Hypochlorous Acid: A New Paradigm for the Septic and Open Abdomen.
CONCLUSIONS: Based on the results of this study, the authors believe instillation through the TAC device may be the next evolution in the use of abdominal NPWT and programmed intermittent lavage of the peritoneal cavity represents an effective method in the care of patients with a septic OA. PMID: 32155118 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - March 12, 2020 Category: General Medicine Tags: Wounds Source Type: research

Surgical Management of Lower Extremity Pyoderma Gangrenosum With Viable Cryopreserved Umbilical Tissue: A Case Series.
CONCLUSIONS: To the best of the authors' knowledge, this is the first case series demonstrating the ability of vCUT to heal these difficult-to-treat ulcers. In addition, it may be an effective modality to adjunctive management of PG. PMID: 32155119 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - March 12, 2020 Category: General Medicine Tags: Wounds Source Type: research

Use of Oxidized Regenerated Cellulose (ORC)/Collagen/Silver-ORC Dressings Alone or Subsequent to Advanced Wound Therapies in Complex Wounds.
CONCLUSIONS: Use of advanced treatment modalities including NPWT, epidermal grafting, and ORC/collagen/silver-ORC dressings contributed to wound healing in these patients with complex and/or chronic wounds. PMID: 32155120 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - March 12, 2020 Category: General Medicine Tags: Wounds Source Type: research

Use of a Remote Temperature Monitoring Mat for the Early Identification of Foot Ulcers.
CONCLUSIONS: In each of these cases, the RTM mat detected inflammation accompanying a preulcerative lesion or a partial-thickness wound, allowing for timely intervention and treatment, including debridement and offloading, which may have the potential to improve care and reduce morbidity, mortality, and costs. PMID: 32155121 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - March 12, 2020 Category: General Medicine Tags: Wounds Source Type: research

Acute Radiation Therapy-related Dermatitis.
Authors: Bolton L Abstract Radiation therapy (RT) following breast-conserving surgical excision of cancer reduces cancer-related mortality and recurrence.1 However, most patients experience acute radiation dermatitis (ARD) within weeks after beginning RT2; symptoms of ARD, including severe skin erythema, dryness, moist or dry desquamation, and/or ulceration, may interrupt radiotherapy. This can negatively affect patient quality of life (QoL) and cancer outcomes. Acute radiation dermatitis is not to be confused with chronic radiation dermatitis, which can lead to fibrosis, skin atrophy, pigmentation, and telangiecta...
Source: Wounds - March 12, 2020 Category: General Medicine Tags: Wounds Source Type: research

Human-derived Acellular Dermal Matrix Grafts for Treatment of Diabetic Foot Ulcers: A Systematic Review and Meta-analysis.
CONCLUSIONS: This study shows H-ADMs are associated with a higher likelihood of complete healing and fewer days to complete healing within a 12-week and 16-week periods when compared with SOC. Also, the commercial products performed similarly. PMID: 32155123 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - March 12, 2020 Category: General Medicine Tags: Wounds Source Type: research

Advanced Treatment Options of Pyoderma Gangrenosum Ulcers.
CONCLUSIONS: The new possibilities offered by NPWT with nonadhesive foam and regenerative medicine are typically affordable, effective, safe, and painless for the patient. Both methods were noninvasive, did not accelerated the pathergy phenomenon, and showed a potential for faster healing of PG ulcers. PMID: 32155124 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - March 12, 2020 Category: General Medicine Tags: Wounds Source Type: research

Treating Wounds With an Avascular Component With a Dermal Regenerative Template.
CONCLUSIONS: This literature review and retrospective study confirm the DRT is a viable option to provide vascularized coverage over wounds with avascular components. This study suggests the DRT is more reliable in wounds with less than 1.9% avascular tissues and less successful in chronic wounds. PMID: 32155125 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - March 12, 2020 Category: General Medicine Tags: Wounds Source Type: research

Amniotic Suspension Allograft and Fetal Bovine Acellular Dermal Matrix to Treat Complex, Acute, Full-thickness Wounds: A Retrospective Analysis of Safety and Treatment Efficacy.
CONCLUSIONS: In a small but challenging population including a high number of patients with comorbidities and exposed bone or tendon, it was found that ASA delivery, along with a dermal matrix, was successful in treating large, complex, acute wounds. PMID: 32155126 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - March 12, 2020 Category: General Medicine Tags: Wounds Source Type: research

Clinical and Economic Impact of a Two-layer Compression System for the Treatment of Venous Leg Ulcers: A Systematic Review.
CONCLUSIONS: Based on these findings, 2LBA may result in lower treatment costs and better ulcer healing and HRQoL compared with other multicomponent therapies, especially in patients with newly diagnosed VLUs. However, further high-quality research is needed, especially for outcomes such as slippage and bandage wear time. PMID: 32155127 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - March 12, 2020 Category: General Medicine Tags: Wounds Source Type: research

Infection and Inflammation in the Wound Environment: Addressing Issues of Delayed Wound Healing With Advanced Wound Dressings.
Authors: Gabriel A, Barrett C, Cullen B, Hodges D, Lee W, Snyder R, Speyrer M, Suski M, Dick S, Thomason HA, Treadwell T Abstract Impaired wound healing is estimated to affect about 2% of the US population, and a major goal of health care providers (HCPs) is to better understand delayed healing so they can effectively choose advanced wound dressings to manage these wounds. However, there are estimated to be more than 3000 dressing options available, making dressing selection an overwhelming burden. An expert panel of 7 HCPs experienced in diverse medical disciplines and 3 scientists convened to discuss the use of 2...
Source: Wounds - December 28, 2019 Category: General Medicine Tags: Wounds Source Type: research

Comparative Effectiveness of Two Collagen-containing Dressings: Oxidized Regenerated Cellulose (ORC)/Collagen/Silver-ORC Dressing Versus Ovine Collagen Extracellular Matrix.
CONCLUSIONS: According to this comparative effectiveness study using real world data, ORC/collagen/silver-ORC dressing appears to afford improved healing and reduced time to granulation relative to ovine collagen ECM dressing. PMID: 31876511 [PubMed - in process] (Source: Wounds)
Source: Wounds - December 28, 2019 Category: General Medicine Tags: Wounds Source Type: research

Biological Mesh Combined With Topical Negative Pressure Therapy in Complex Abdominal Wounds: A Short Series and a Review of the Literature.
CONCLUSIONS: From these cases and the review of the literature, the authors believe TNP can be applied on a biological mesh with effectiveness in improving the treatment of the CAWs without relevant risk to the patient or biological mesh. PMID: 31876512 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - December 28, 2019 Category: General Medicine Tags: Wounds Source Type: research

Clinical Efficacy of Acellular Dermal Matrix Paste in Treating Diabetic Foot Ulcers.
CONCLUSIONS: The ADM paste effectively enhanced tissue regeneration, shortening ulcer duration and preventing associated complications, while eliminating the need for supplemental ulcer management procedures. The paste formulation of ADM provides a matrix for tissue ingrowth, promoting the healing of DFUs. PMID: 31876513 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - December 28, 2019 Category: General Medicine Tags: Wounds Source Type: research

Treatment of Traumatic Degloving Injury of the Foot Using a Biologic Dressing in a Pediatric Patient.
CONCLUSIONS: To the best of the authors' knowledge, this is the first reported case in which an instance of pediatric foot degloving is presented with serial debridement, NPWT, and biological dressings, resulting in no additional plastic surgical techniques needed to provide return to functional outcome. PMID: 31876514 [PubMed - in process] (Source: Wounds)
Source: Wounds - December 28, 2019 Category: General Medicine Tags: Wounds Source Type: research

The Use of an Autologous Cell Harvesting and Processing Device to Decrease Surgical Procedures and Expedite Healing in Two Pediatric Burn Patients.
CONCLUSIONS: These cases are the first of their kind reported in the pediatric population and suggest ACS in conjunction with STSGs can help decrease surgical procedures and expedite healing in pediatric patients with large surface burns. PMID: 31833837 [PubMed - in process] (Source: Wounds)
Source: Wounds - December 14, 2019 Category: General Medicine Tags: Wounds Source Type: research

Burn Debridement: Are We Optimizing Outcomes?
Authors: Bolton L Abstract Early surgical debridement of nonviable tissue within 48 hours of burn injury is the standard of care (SOC) for burns extending into and beyond the deep dermis. Early debridement has been reported to reduce infection and complication rates, shorten hospital stays, and improve burn wound healing compared with delayed debridement of these burns.1 However, surgical debridement challenges patients with considerable pain, blood and heat loss, and poor differentiation between viable and dead tissue resulting in unnecessary excision of healthy tissue.2 Alternative debridement interventions, such...
Source: Wounds - December 14, 2019 Category: General Medicine Tags: Wounds Source Type: research

RE: Large-defect Resurfacing: A Comparison of Skin Graft Results Following Sarcoma Resection and Traumatic Injury Repair.
Authors: Hundeshagen G, Kneser U Abstract We have read the article by Hanada et al1 from the July 2019 issue of Wounds with great interest and acknowledge that split-thickness skin grafting (STSG) following sarcoma resection is a feasible and noninvasive means of defect reconstruction. The comparison to traumatic defects certainly underpins the safety and efficacy of the method. However, regarding the given defect sizes and localizations, as well as associated defects in tissue volume, we propose free or pedicled flap reconstruction not only would have been feasible, but superior to STSG in most of their1 cases. ...
Source: Wounds - November 21, 2019 Category: General Medicine Tags: Wounds Source Type: research

Effects of Bathing Habits on Postoperative Wound Complications Following Sacrococcygeal Pilonidal Sinus Surgery: A Retrospective Analysis of 67 Adolescent Patients.
CONCLUSIONS: Postoperative wound complications in adolescent patients treated with Karydakis flap surgery for sacrococcygeal pilonidal sinus are more frequent in those who bathe more than twice weekly during the first 28 days postoperatively. PMID: 31747369 [PubMed - in process] (Source: Wounds)
Source: Wounds - November 21, 2019 Category: General Medicine Tags: Wounds Source Type: research

Acellular Fish Skin Graft Use for Diabetic Lower Extremity Wound Healing: A Retrospective Study of 58 Ulcerations and a Literature Review.
CONCLUSIONS: This retrospective study further supports previous evidence that acellular fish skin graft promotes wound healing in DFUs. In particular, a rapid increase in wound healing was observed during the initial 4 weeks following graft application. This study and review of the literature indicated that fish graft encourages wound healing by enabling the wound to transition from a chronic to an acute stage of healing. PMID: 31730505 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - November 18, 2019 Category: General Medicine Tags: Wounds Source Type: research

Preventing Fall Injury.
Authors: Bolton L Abstract Falls are the leading cause of injury, premature institutionalization, and long-term disability in elderly adults worldwide, with a fall-related fatality in the United States every 19 minutes.1 According to the Centers for Disease Control and Prevention,2 3 million people over 65 years of age receive emergency room treatment for fall injuries at an average cost of $30 000. The annual cost of fall injuries was more than $50 billion in 2015.1,2 Community-based interventions effective in preventing falls include exercise, medication, and nutritional management as well as improving safety of ...
Source: Wounds - November 18, 2019 Category: General Medicine Tags: Wounds Source Type: research

Efficient Silver Release From Ion Exchange Silver Dressings in Biologically Relevant Media.
CONCLUSIONS: The ion exchange (Ag+ complex) silver dressing was shown to be the most efficient among all the dressings tested for silver release. PMID: 31730507 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - November 18, 2019 Category: General Medicine Tags: Wounds Source Type: research

Resveratrol Exerts Therapeutic Effects on Mice With Atopic Dermatitis.
CONCLUSIONS: These results suggest resveratrol has therapeutic effects in the treatment of AD. PMID: 31730508 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - November 18, 2019 Category: General Medicine Tags: Wounds Source Type: research

Outcomes of Split-thickness Skin Grafting for Foot and Ankle Wounds in Patients With Peripheral Arterial Disease.
CONCLUSIONS: These results suggest the importance of arterial-arterial connections such as the pedal arch to the healing potential of foot and ankle wounds after STSG in this high-risk patient population. PMID: 31730509 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - November 18, 2019 Category: General Medicine Tags: Wounds Source Type: research

A Four-step Technique for Effluent Diversion of Enteroatmospheric Fistulas.
CONCLUSIONS: This is an easily reproducible and safe technique for effluent control in patients with Björk grade 4 abdomen with established EAF. PMID: 31730510 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - November 18, 2019 Category: General Medicine Tags: Wounds Source Type: research

Treatment of Frostbite With Hyperbaric Oxygen Therapy: A Single Center's Experience of 22 Cases.
CONCLUSIONS: This is the largest cohort reported in the literature of patients with frostbite injuries treated with HBOT. Hyperbaric oxygen therapy may show positive impact on the demarcation level of frostbite and, despite the common side effects, it generally causes no long-term sequelae. PMID: 31730511 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - November 18, 2019 Category: General Medicine Tags: Wounds Source Type: research

Development of an Illustrated Guide to Techniques of Dressing Application in the Patient With Burns.
CONCLUSIONS: An illustrated guide for dressing application in burn wounds was developed and validated for content by an expert panel. PMID: 31730512 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - November 18, 2019 Category: General Medicine Tags: Wounds Source Type: research

Skin Burns: Review of Molecular Mechanisms and Therapeutic Approaches.
Authors: Roshangar L, Soleimani Rad J, Kheirjou R, Reza Ranjkesh M, Ferdowsi Khosroshahi A Abstract Burn wounds are one of the main causes of skin damage. Based on World Health Organization statistics, almost 300 000 people worldwide die of burns each year. In severe burns, the cells and blood vessels are often injured and the blood supply to the wound is disturbed. Many factors such as oxygenation, infection, aging, hormones, and nutrition potentially can influence burn progression and disrupt repair with unbalanced release of various growth factors and cytokines. Different treatment approaches such as dressings a...
Source: Wounds - November 18, 2019 Category: General Medicine Tags: Wounds Source Type: research

Comparing the Therapeutic Value of Negative Pressure Wound Therapy and Negative Pressure Wound Therapy With Instillation and Dwell Time in Bilateral Leg Ulcers: A Case Report.
CONCLUSIONS: From this case report, the authors believe NPWTi-d may be more effective in cases with intractable ulcers associated with infection that need better granulation. PMID: 31730514 [PubMed - in process] (Source: Wounds)
Source: Wounds - November 18, 2019 Category: General Medicine Tags: Wounds Source Type: research

Stasis Mucinosis: Insights Into Euthyroid Localized Mucinosis.
CONCLUSIONS: The authors suggest stasis mucinosis and OALM represent the spectrum of euthyroid mucin depositional disease in varying clinical settings. PMID: 31730515 [PubMed - in process] (Source: Wounds)
Source: Wounds - November 18, 2019 Category: General Medicine Tags: Wounds Source Type: research

Lower Extremity Skin Ulcer Associated With Neurofibromatosis Type 1: A Case Report.
CONCLUSIONS: Cutaneous vasculopathy related to the skin, such as livedo reticularis and ulcers of torpid evolution due to cutaneous vasculopathy are extremely rare. Thus, it is necessary to include skin ulcers as one of the phenotypic manifestations of NF-1. PMID: 31730516 [PubMed - in process] (Source: Wounds)
Source: Wounds - November 18, 2019 Category: General Medicine Tags: Wounds Source Type: research

Uncooperative Patient With an Infected Elbow Osteosynthesis: Alternative Management With Topical Sevoflurane.
CONCLUSIONS: Local application of sevoflurane in the wound bed appears to exhibit analgesic, antimicrobial, and positive healing effects. It could be a promising alternative treatment to be included as a therapeutic option for wound care. PMID: 31730517 [PubMed - in process] (Source: Wounds)
Source: Wounds - November 18, 2019 Category: General Medicine Tags: Wounds Source Type: research

Benefits of a Patient-centered Remote Therapy Monitoring Program Focusing on Increased Adherence to Wound Therapy.
CONCLUSIONS: In these 3 cases, RTM-equipped NPWT and the patient-centric exchanges with the VTS through adherence calls helped promote consistent usage of RTM-equipped NPWT to address the patients' therapeutic needs and increase therapy adherence. PMID: 31483754 [PubMed - in process] (Source: Wounds)
Source: Wounds - September 5, 2019 Category: General Medicine Tags: Wounds Source Type: research

Successful Treatment of Single Infected Calciphylaxis Lesion With Intralesional Injection of Sodium Thiosulfate at High Concentration.
CONCLUSIONS: The authors believe a higher local concentration of STS leading to a faster resolution and requiring less frequent injections needs to be further evaluated. Following additional studies, they also propose a greater use of intralesional STS injections in a select set of patients in the future. PMID: 31483755 [PubMed - in process] (Source: Wounds)
Source: Wounds - September 5, 2019 Category: General Medicine Tags: Wounds Source Type: research

The Risk Factors of Postoperative Pressure Ulcer After Liver Resection With Long Surgical Duration: A Retrospective Study.
CONCLUSIONS: These results showed length of surgery and intraoperative blood loss were independent risk factors for PU after liver resection with a long surgical duration. Use of PU prevention strategies are recommended for patients who undergo liver resection with massive intraoperative blood loss and long surgical duration. PMID: 31461399 [PubMed - in process] (Source: Wounds)
Source: Wounds - August 29, 2019 Category: General Medicine Tags: Wounds Source Type: research

Does Debridement Improve Clinical Outcomes in People With Diabetic Foot Ulcers Treated With Continuous Diffusion of Oxygen?
CONCLUSIONS: A significantly greater percentage of healing was recorded in patients receiving active CDO therapy than those receiving a placebo device in addition to standard wound care with identical dressings, debridement recommendations, and offloading. The relative performance of CDO appears to increase with the use of frequent debridement. PMID: 31461400 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - August 29, 2019 Category: General Medicine Tags: Wounds Source Type: research

Effect of Weekly Specialized Surgeon-led Bedside Wound Care Teams on Pressure Ulcer Time-to-heal Outcomes: Results From a National Dataset of Long-term Care Facilities.
CONCLUSIONS: Pressure ulcers managed by coordinated nursing and weekly SLBTs appear to heal significantly faster than wounds managed by UC. Further studies are required to confirm these hypothesis-generating results. PMID: 31461401 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - August 29, 2019 Category: General Medicine Tags: Wounds Source Type: research

Platelet-rich Plasma Improves Healing of Pressure Ulcers as Objectively Assessed by Digital Planimetry.
CONCLUSIONS: It appears treatment with PRP accelerates healing of PUs as objectively measured by digital planimetry. Compared with conventional treatment, a significantly higher reduction in surface area, diameter, and circumference of PUs was observed following application of PRP. PMID: 31461402 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - August 29, 2019 Category: General Medicine Tags: Wounds Source Type: research

Allograft of Primary Cutaneous Mucormycosis in a Preterm Neonate: A Case Report.
CONCLUSIONS: While PCM can be fatal for many preterm infants, debridement with allografting may serve as a valuable treatment option with fewer associated complications for neonates as they are stabilizing clinically. PMID: 31373557 [PubMed - in process] (Source: Wounds)
Source: Wounds - August 4, 2019 Category: General Medicine Tags: Wounds Source Type: research

Ilioinguinal Flap Combined With Tensor Fascia Lata Muscle Flap to Repair Deep Electrical Burns in the Lower Abdomen: A Report of Two Cases.
CONCLUSIONS: Transfer of flaps from a site near the wound for repairing electrical burns is convenient for transfer with minimal surgical trauma and a simpler operating procedure than the free flap. PMID: 31373558 [PubMed - in process] (Source: Wounds)
Source: Wounds - August 4, 2019 Category: General Medicine Tags: Wounds Source Type: research

Topical Burn Wound Management.
Authors: Bolton L Abstract Cutaneous burns challenge global health care systems with high patient morbidity and mortality rates.1 One recent study of adults admitted for 2 to 60 days to a US burn center reported that more than 7.9% of burn patients experienced at least 1 hospital-acquired infection (HAI), extending the hospital length of stay and increasing the likelihood of complications and death.2 Of these HAIs, most (35.8%) were skin and soft tissue infections, followed by respiratory (24.4%), bloodstream (18.1%), and urinary tract (17.8%) infections. A burn covering more than 5% of total body surface area (TBS...
Source: Wounds - July 30, 2019 Category: General Medicine Tags: Wounds Source Type: research

The Effect of Withholding Antibiotics Prior to Bone Biopsy in Patients With Suspected Osteomyelitis: A Meta-analysis of the Literature.
CONCLUSIONS: When all studies as well as when NVO studies only were evaluated, there was no significant difference in bacterial pathogen yield based on antibiotic exposure. When VO studies were evaluated separately, there were fewer pathogens recovered than when antibiotics were administered prior to obtaining bone cultures. PMID: 31356178 [PubMed - in process] (Source: Wounds)
Source: Wounds - July 30, 2019 Category: General Medicine Tags: Wounds Source Type: research

Large-defect Resurfacing: A Comparison of Skin Graft Results Following Sarcoma Resection and Traumatic Injury Repair.
CONCLUSIONS: The results of skin grafting for resurfacing large defects after sarcoma resection are inferior to those for traumatic injury repair. Skin grafts may fail because the blood supply for the wound bed is impaired during resection. Furthermore, due to the wound bed movement, epithelialization over muscles of the shoulder joint is difficult to achieve, and skin grafts in this region will likely fail. PMID: 31306097 [PubMed - in process] (Source: Wounds)
Source: Wounds - July 16, 2019 Category: General Medicine Tags: Wounds Source Type: research

HS-TIME: A Modified TIME Concept in Hidradenitis Suppurativa Topical Management.
CONCLUSIONS: Considering the lack of strong evidence regarding wound care in HS, the authors propose the new concept of HS-TIME, based on the TIME wound bed preparation rules, as a new, helpful, easy-to-use tool that may assist physicians in identifying the best wound approach in these patients. PMID: 31298658 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - July 13, 2019 Category: General Medicine Tags: Wounds Source Type: research

Efficacy and Safety of 4% Hibiscus rosa-sinensis Leaf Extract Ointment as an Adjunct Treatment to Compression Stockings on the Closure of Venous Leg Ulcers: A Pilot Study.
CONCLUSIONS: Data showed compression stockings with 4% gumamela leaf extract ointment application could close VLUs in ⟨ 12 weeks. Applied with compression stockings, the ointment shows potential use in VLU management. PMID: 31298659 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - July 13, 2019 Category: General Medicine Tags: Wounds Source Type: research

Comparison of Efficacy and Complications Between Negative Pressure Wound Therapy and Conventional Mechanical Fixation in Skin Grafts: A Retrospective Analysis.
CONCLUSIONS: This study reports a quantitative analysis of the efficacy of NPWT on skin graft fixation with NPWT providing consistent pressure and better drainage than conventional mechanical fixation. In addition, the use of NPWT also could increase graft take on the hand region. PMID: 31298660 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - July 13, 2019 Category: General Medicine Tags: Wounds Source Type: research