Association of Negative Pressure Wound Therapy and Dermatotraction for Management of Necrotizing Soft Tissue Infections: A Case Series.
CONCLUSIONS: Based on the experiences herein, NPWT-D may be a safe and useful alternative surgical treatment for the management of necrotizing STIs. In the present cases, NPWT-D improved and shortened the wound healing process, and it achieved a tertiary wound closure, thereby avoiding the need for skin grafts. PMID: 33166261 [PubMed - in process] (Source: Wounds)
Source: Wounds - November 12, 2020 Category: General Medicine Tags: Wounds Source Type: research

Health Care Spending in Patients With Stage 3 and Stage 4 Pressure Injuries and Patients With Diabetic Foot Ulcers Treated Early With Clostridial Collagenase Ointment: A Retrospective Data Review.
CONCLUSIONS: Early initiation of CCO provides both all-cause and disease-related health care savings to payers and persons managing patients with PIs or DFUs. Payers, providers, and facilities should consider mechanisms to encourage the early use of CCO to lower costs. PMID: 33166262 [PubMed - in process] (Source: Wounds)
Source: Wounds - November 12, 2020 Category: General Medicine Tags: Wounds Source Type: research

Wound Phototherapy.
Authors: Bolton LL Abstract Researchers have tested the effects of low-level light therapy (LLLT) using low-power lasers or non-coherent, non-collimated light therapy from light-emitting diodes (LEDs) on wounds for decades, exploring the efficacy of phototherapy treatments for chronic1 and acute2 wounds. Low-level light therapy has received device clearance in the United States for cosmetic improvement of aging or sun-damaged skin, acne, actinic keratoses, non-melanoma skin cancer, improving circulation, and decreasing pain as well as stiffness and muscle spasm. 3 It has been used for dental, dermatologic, neurolog...
Source: Wounds - November 12, 2020 Category: General Medicine Tags: Wounds Source Type: research

The Effect of Topical Administration of an Ointment Prepared From Trifolium repens Hydroethanolic Extract on the Acceleration of Excisional Cutaneous Wound Healing.
CONCLUSIONS: The topical administration of T repens accelerated wound healing by increasing angiogenesis; fibroblast, fibrocyte, and mast-cell distribution; intracytoplasmic carbohydrate storage; and modulation in genes involved in apoptosis in a rat model. PMID: 33166264 [PubMed - in process] (Source: Wounds)
Source: Wounds - November 12, 2020 Category: General Medicine Tags: Wounds Source Type: research

A Literature Review of Pharmacological Agents to Improve Venous Leg Ulcer Healing.
Authors: Kitchens BP, Snyder RJ, Cuffy CA Abstract Compression therapy is the gold standard treatment for venous leg ulcers (VLUs); however, with adjunctive pharmacological therapies and poor patient adherence using compressive dressings, clinicians are looking to find the advantage in treating VLUs. This literature review focuses on the efficacy of pharmacological agents, quality of life using agents in addition to compression therapy, and cost effectiveness to indicate the best outcomes for pharmacological treatment of VLUs. The following available venotonic, hemorheologic, and fibrinolytic agents were reviewed f...
Source: Wounds - November 12, 2020 Category: General Medicine Tags: Wounds Source Type: research

The Risk of Infection and Indication of Systemic Antibiotics in Chronic Wounds.
CONCLUSIONS: The WAR score can help guide clinicians in determining the need for antibiotics, thus helping to reduce unnecessary antibiotic exposure, which can reduce the incidence of adverse drug events and multidrug-resistant organisms. PMID: 33166266 [PubMed - in process] (Source: Wounds)
Source: Wounds - November 12, 2020 Category: General Medicine Tags: Wounds Source Type: research

Development of a Manual on the Technique of Applying the Unna Boot in Patients With Venous Leg Ulcers.
CONCLUSIONS: A manual on the technique of applying the Unna boot in patients with VLUs was developed and validated for content by an expert panel. PMID: 33166267 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - November 12, 2020 Category: General Medicine Tags: Wounds Source Type: research

Predictors of Surgical Site Infections Among Patients With Diabetes Mellitus Post Coronary Artery Bypass Graft Surgery: A Quasi-experimental Study.
CONCLUSIONS: Three key factors were found to predict the occurrence of SSIs in patients with DM undergoing CABG. These findings underscore the necessity for health care providers to adhere to and employ meticulous infection control practices when managing at-risk CABG patients. PMID: 33166268 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - November 12, 2020 Category: General Medicine Tags: Wounds Source Type: research

Early and Sequential Punch Grafting in the Spectrum of Arteriolopathy Ulcers in the Elderly.
CONCLUSIONS: Early punch grafting is an effective technique for pain control and healing promotion in Martorell ulcers. Punch grafting, which may be performed in an outpatient setting, is well tolerated by patients and may be repeated several times if necessary. PMID: 33166269 [PubMed - in process] (Source: Wounds)
Source: Wounds - November 12, 2020 Category: General Medicine Tags: Wounds Source Type: research

Calciphylaxis in Stage 3 Chronic Kidney Disease on Apixaban Successfully Treated With Sodium Thiosulfate: A Case Report.
CONCLUSIONS: This case illustrates that early diagnosis, intervention, and a multidisciplinary approach are of utmost importance in the management of calciphylaxis. Sodium thiosulfate, when used in the correct setting, can improve prognosis in patients. Serious consideration should be given to sodium thiosulfate as a practical measure of treatment. PMID: 33166270 [PubMed - in process] (Source: Wounds)
Source: Wounds - November 12, 2020 Category: General Medicine Tags: Wounds Source Type: research

Prospective, Single-center, Open-label, Pilot Study Using Cryopreserved Umbilical Tissue Containing Viable Cells in the Treatment of Complex Acute and Chronic Wounds.
CONCLUSIONS: The results of this study suggest vCUT in conjunction with standard of care can be a viable treatment option for acute and chronic lower extremity complex wounds. PMID: 32813668 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - August 21, 2020 Category: General Medicine Tags: Wounds Source Type: research

Treatment of Hard-to-heal Diabetic Foot Ulcers With a Hepatic-derived Wound Matrix.
CONCLUSIONS: The HD-WM under evaluation did well at closing difficult-to-heal wounds with minimal applications. These results are consistent with a previous study on this HD-WM. PMID: 32813669 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - August 21, 2020 Category: General Medicine Tags: Wounds Source Type: research

Topical Products for the Protection of Periwound Skin: A Scoping Review.
CONCLUSIONS: To date, the level of evidence is low. It is necessary to develop more robust research that improves the quality of the literature available for treating people with wounds. PMID: 32813670 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - August 21, 2020 Category: General Medicine Tags: Wounds Source Type: research

Multiple Beneficial Effects of High-dose BoNT-A Injection to Improve Wound Healing and Spasticity in a Patient With Hypoxic Encephalopathy Due to High-voltage Electrical Injury.
CONCLUSIONS: For patients with hypoxic encephalopathy due to high-voltage electrical injury, botulinum toxin type A injection may be an option of therapeutic approach for both reduction of spasticity and facilitation of wound healing. PMID: 32813671 [PubMed - in process] (Source: Wounds)
Source: Wounds - August 21, 2020 Category: General Medicine Tags: Wounds Source Type: research

Initial Experience Using Disposable Negative Pressure Wound Therapy for Closed Incisions Following Outpatient Wound Reconstruction.
Authors: Desvigne MN, Berman ML, Villanueva DS, Fawcett K, Aragon J, Wardman AL, Moya J Abstract Wound reconstruction surgeries are at high risk for failure. Outpatient wound reconstruction (OWR) describes these procedures performed in the outpatient setting under local anesthesia. The use of closed incision negative pressure therapy (ciNPT) has been shown to protect the incision and help minimize the risk of postoperative complications. To date, this has not been readily adopted in the outpatient setting. The authors report their initial experience with 3 cases of OWR with ciNPT used by the application of disposab...
Source: Wounds - August 21, 2020 Category: General Medicine Tags: Wounds Source Type: research

Treatment of Deep Full-thickness Wounds Containing Exposed Muscle, Tendon, and/or Bone Using a Bioactive Human Skin Allograft: A Large Cohort Case Series.
CONCLUSIONS: This study demonstrates the effectiveness of BSA in the treatment of deep wounds of various etiologies. The authors provide clinical information on using BSA either alone or in conjunction with other advanced modalities and offer insight into the hypothesized mechanism of action in which these grafts become incorporated. Ultimately, this information can guide best practices in the treatment of full-thickness wounds to improve outcomes. PMID: 32804658 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - August 18, 2020 Category: General Medicine Tags: Wounds Source Type: research

Synergistic Effect and Antibiofilm Activity of a Skin and Wound Cleanser.
CONCLUSIONS: The experimental and calculated results indicate the 3 components (VD, EDTA, and PHMB) when used together act synergistically to eradicate MRSA and P aeruginosa biofilms in vitro. PMID: 32804659 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - August 18, 2020 Category: General Medicine Tags: Wounds Source Type: research

Effects of Stents or Prostanoids on Critical Limb Ischemia.
Authors: Bolton L Abstract Peripheral arterial disease (PAD) affects up to 10% of the global population and is often underdiagnosed and inadequately treated until it progresses to critical limb ischemia (CLI) with rest pain, gangrene, and/or ulceration. At this late stage in PAD management, outcomes are typically measured in terms of amputation or mortality. The 5-year mortality rate has been reported to exceed the likelihood of that due to prostate and breast cancer combined. Structured exercise and/or calf muscle stimulation increased collateral circulation, improving pain, quality of life, and mobility outcomes ...
Source: Wounds - August 18, 2020 Category: General Medicine Tags: Wounds Source Type: research

Can Skin Cells Improve Outcomes for Patients With Deep Burns?
Authors: Bolton L Abstract Early excision and split-thickness skin autografts (STSGs) have become standard care for full-thickness burns, but healing the donor site challenges these patients who are already at metabolic and microbial risks, increasing with the total body surface area (TBSA) burned. Engineered skin substitutes containing 1 or more cellular or acellular components of the epidermis, dermis, or hypodermal components have been designed to function as potential STSG replacements, supplementing the barrier or scaffold functions of lost skin. They have reduced the area of STSG tissue needed, helping to imp...
Source: Wounds - August 18, 2020 Category: General Medicine Tags: Wounds Source Type: research

Mitigating the Opioid Crisis for Wound Care Providers Using Opioid Stewardship.
Authors: Smith RG Abstract Opioids are an effective form of analgesia for pain treatment during wound treatment. Overprescribing of opioid agents has become detrimental to the public health of the United States. One of the most difficult challenges for any wound care prescriber is to balance the potential benefits versus the potential risks of opioid prescribing. Addressing the opioid crisis requires an interprofessional team approach. The utilization of an opioid stewardship program provides the necessary framework to identify gaps in the quality and development in the implementation of a change of long-standing o...
Source: Wounds - August 18, 2020 Category: General Medicine Tags: Wounds Source Type: research

Outcomes and Characteristics of Wound Healing in an Outpatient Physical Therapy Clinic.
CONCLUSIONS: Venous leg ulcers and other wound etiologies (ie, STWs, PUs, DFUs, and arterial wounds) appear to differ in wound healing outcomes and certain characteristics. These results may be of interest to clinicians, patients, health care policy makers, and insurers. Future research is warranted to compare wound healing outcomes and patient characteristics among different settings. PMID: 32804663 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - August 18, 2020 Category: General Medicine Tags: Wounds Source Type: research

The Effects of Nitrofurazone on Wound Healing in Thoracoabdominal Full-thickness Skin Defects.
CONCLUSIONS: Topically applied nitrofurazone produced positive effects accelerating the wound healing process. PMID: 32804664 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - August 18, 2020 Category: General Medicine Tags: Wounds Source Type: research

Complex Wound Management Using Negative Pressure Wound Therapy With Instillation and Dwell Time in a Cancer Care Setting.
CONCLUSIONS: As shown in this case series, NPWTi-d was a beneficial tool for cleansing the wound bed, thus creating a moist, closed wound environment conducive to healing. Using NPWTi-d supported the formation of a healthy wound bed and contributed to rapid, positive outcomes in this patient population. PMID: 32804665 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - August 18, 2020 Category: General Medicine Tags: Wounds Source Type: research

High Potential for Complications After Traumatic Exposure in Patients With a Total Knee Replacement.
CONCLUSIONS: Traumatic dehiscence with implant exposure during the initial postoperative period of TKR is an infrequent event (0.1%) with a high potential for complications (75%), which may lead to loss of the prosthesis and even the limb. Measures should be taken to prevent falls and gather reports from several centers to broaden the knowledge of this rare event, identify prognostic factors, and define the best treatment algorithm. PMID: 32804666 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - August 18, 2020 Category: General Medicine Tags: Wounds Source Type: research

Burns Sustained From Body Heating Devices: An Integrative Review.
CONCLUSIONS: Burns from body heating devices are often preventable. Community education and improved manufacture labelling on the appropriate use and potential risks should be required. The patient's cognitive ability and physiology must be considered to minimize incidence and severity of injury. PMID: 32804667 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - August 18, 2020 Category: General Medicine Tags: Wounds Source Type: research

Early-stage Management of Complex Lower Extremity Wounds Using Negative Pressure Wound Therapy With Instillation and a Reticulated Open Cell Foam With Through Holes.
CONCLUSIONS: These data further support the use of NPWTi-d with ROCF-CC to help manage complex wounds of the lower limb. PMID: 32335516 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - April 28, 2020 Category: General Medicine Tags: Wounds Source Type: research

Successful Mastectomy and Chemotherapy in a Patient with Breast Cancer and Active Generalized Pyoderma Gangrenosum.
CONCLUSIONS: This unique case highlights the challenging aspects in the medical and perioperative management of active PG in a patient with breast cancer. PMID: 32335517 [PubMed - in process] (Source: Wounds)
Source: Wounds - April 28, 2020 Category: General Medicine Tags: Wounds Source Type: research

Liposuction Treatment of a Subacute Morel-Lavall ée Lesion: A Case Report.
CONCLUSIONS: This case of MLL was diagnosed early and successfully treated with liposuction, resulting in an acceptable cosmetic outcome. It is the authors' hope that this case report will lead to earlier diagnosis and proper treatment of MLLs. PMID: 32335518 [PubMed - in process] (Source: Wounds)
Source: Wounds - April 28, 2020 Category: General Medicine Tags: Wounds Source Type: research

Efficacy of a Urinary Bladder Matrix for Treating Wound Dehiscence With Hardware Exposure in a Patient With Rheumatoid Arthritis.
CONCLUSIONS: Wound healing was accomplished without removal of the exposed deep hardware in a patient with comorbidities and post-surgical wound dehiscence. PMID: 32335519 [PubMed - in process] (Source: Wounds)
Source: Wounds - April 28, 2020 Category: General Medicine Tags: Wounds Source Type: research

Wound Center Without Walls: The New Model of Providing Care During the COVID-19 Pandemic.
Authors: Rogers LC, Armstrong DG, Capotorto J, Fife CE, Garcia JR, Gelly H, Gurtner GC, Lavery LA, Marston W, Neville R, Nusgart M, Ravitz K, Woelfel S Abstract The COVID-19 pandemic poses a major challenge in delivering care to wound patients. Due to multiple comorbidities, wound patients are at an increased risk for the most extreme complications of COVID-19 and providers must focus on reducing their exposure risk. The Federal, State, and local governments, as well as payers, have urged hospitals and providers to reduce utilization of nonessential health services, but they also have given more flexibility to shif...
Source: Wounds - April 28, 2020 Category: General Medicine Tags: Wounds Source Type: research

Application of Chitosan and Chondroitin Sulphate Aerogels in a Patient With Diabetes With an Open Forefoot Transmetatarsal Amputation.
CONCLUSIONS: Due to the results of this patient, use of ChS and CS aerogels could represent an alternative treatment for forefoot TMA wound closure and prevent further surgical procedures, such as skin grafting. Future works should consider a larger number of cases. PMID: 32335521 [PubMed - in process] (Source: Wounds)
Source: Wounds - April 28, 2020 Category: General Medicine Tags: Wounds Source Type: research

Combining the Benefits of Collagen and Negative Pressure Wound Therapy to Heal a Chronic Diabetic Foot Ulcer: A Case Report.
CONCLUSIONS: The combination of a collagen wound contact layer and weekly NPWT had a significantly positive effect on healing in this chronic DFU. The regimen was well-tolerated and simple to administer in this case. PMID: 32335522 [PubMed - in process] (Source: Wounds)
Source: Wounds - April 28, 2020 Category: General Medicine Tags: Wounds Source Type: research

Micropore Particle Technology Promotes Wound Healing, Whereas Polyhexamethylene Biguanide Causes Tissue Degeneration: A Case Report.
CONCLUSIONS: It is generally assumed that the cytotoxic properties of antiseptics seen in cell culture experiments do not occur on wounds. The present case shows these cytotoxic properties are expressed on wounds, and they do disrupt tissues and tissue regeneration. PMID: 32335523 [PubMed - in process] (Source: Wounds)
Source: Wounds - April 28, 2020 Category: General Medicine Tags: Wounds Source Type: research

Lymphedema: A Practical Approach and Clinical Update.
Authors: Bittar S, Simman R, Lurie F Abstract The lymphatic system is arguably the most neglected bodily system. As a result, its contribution to human health and disease is not well understood. In this review, the clinical approaches based on new knowledge and developments of the lymphatic system are covered. The lymphatic system has 3 major functions: (1) the preservation of fluid balance; (2) a nutritional function, as intestinal lymphatics are responsible for fat absorption; and (3) host defense. Lymph vessels return the capillary ultrafiltrate and escaped plasma proteins from most tissues back, ultimately, to ...
Source: Wounds - March 14, 2020 Category: General Medicine Tags: Wounds Source Type: research

Topical Oxygen Therapy Shifts Microbiome Dynamics in Chronic Diabetic Foot Ulcers.
CONCLUSIONS: Although the sample size was small, this study suggests topical oxygen therapy may have the ability to encourage the growth of aerobic members of the wound microbiome and be an effective alternative to antibiotics in this area. PMID: 32163040 [PubMed - in process] (Source: Wounds)
Source: Wounds - March 14, 2020 Category: General Medicine Tags: Wounds Source Type: research

Bacterial Species and Load Increase During Negative Pressure Wound Therapy: A Prospective Cohort Study.
CONCLUSIONS: The number of S aureus strains and overall bacterial load increased during NPWT, and the incidence of infection remained the same. Further studies should be conducted to determine whether the increase in bacterial load influences other wound outcome parameters. PMID: 32163041 [PubMed - in process] (Source: Wounds)
Source: Wounds - March 14, 2020 Category: General Medicine Tags: Wounds Source Type: research

Laser Therapy Induces Increased Viability and Proliferation in Isolated Fibroblast Cells.
CONCLUSIONS: The findings of this study show LT increased fibroblast cell proliferation, depending on the power output level of the laser and number of applications. In addition to the proliferation and mitotic activity of the fibroblast cells, the results demonstrate that LT could increase wound healing after oral surgery and periodontal treatments. PMID: 32163042 [PubMed - in process] (Source: Wounds)
Source: Wounds - March 14, 2020 Category: General Medicine Tags: Wounds Source Type: research

Intraabdominal Lavage of Hypochlorous Acid: A New Paradigm for the Septic and Open Abdomen.
CONCLUSIONS: Based on the results of this study, the authors believe instillation through the TAC device may be the next evolution in the use of abdominal NPWT and programmed intermittent lavage of the peritoneal cavity represents an effective method in the care of patients with a septic OA. PMID: 32155118 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - March 11, 2020 Category: General Medicine Tags: Wounds Source Type: research

Surgical Management of Lower Extremity Pyoderma Gangrenosum With Viable Cryopreserved Umbilical Tissue: A Case Series.
CONCLUSIONS: To the best of the authors' knowledge, this is the first case series demonstrating the ability of vCUT to heal these difficult-to-treat ulcers. In addition, it may be an effective modality to adjunctive management of PG. PMID: 32155119 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - March 11, 2020 Category: General Medicine Tags: Wounds Source Type: research

Use of Oxidized Regenerated Cellulose (ORC)/Collagen/Silver-ORC Dressings Alone or Subsequent to Advanced Wound Therapies in Complex Wounds.
CONCLUSIONS: Use of advanced treatment modalities including NPWT, epidermal grafting, and ORC/collagen/silver-ORC dressings contributed to wound healing in these patients with complex and/or chronic wounds. PMID: 32155120 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - March 11, 2020 Category: General Medicine Tags: Wounds Source Type: research

Use of a Remote Temperature Monitoring Mat for the Early Identification of Foot Ulcers.
CONCLUSIONS: In each of these cases, the RTM mat detected inflammation accompanying a preulcerative lesion or a partial-thickness wound, allowing for timely intervention and treatment, including debridement and offloading, which may have the potential to improve care and reduce morbidity, mortality, and costs. PMID: 32155121 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - March 11, 2020 Category: General Medicine Tags: Wounds Source Type: research

Acute Radiation Therapy-related Dermatitis.
Authors: Bolton L Abstract Radiation therapy (RT) following breast-conserving surgical excision of cancer reduces cancer-related mortality and recurrence.1 However, most patients experience acute radiation dermatitis (ARD) within weeks after beginning RT2; symptoms of ARD, including severe skin erythema, dryness, moist or dry desquamation, and/or ulceration, may interrupt radiotherapy. This can negatively affect patient quality of life (QoL) and cancer outcomes. Acute radiation dermatitis is not to be confused with chronic radiation dermatitis, which can lead to fibrosis, skin atrophy, pigmentation, and telangiecta...
Source: Wounds - March 11, 2020 Category: General Medicine Tags: Wounds Source Type: research

Human-derived Acellular Dermal Matrix Grafts for Treatment of Diabetic Foot Ulcers: A Systematic Review and Meta-analysis.
CONCLUSIONS: This study shows H-ADMs are associated with a higher likelihood of complete healing and fewer days to complete healing within a 12-week and 16-week periods when compared with SOC. Also, the commercial products performed similarly. PMID: 32155123 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - March 11, 2020 Category: General Medicine Tags: Wounds Source Type: research

Advanced Treatment Options of Pyoderma Gangrenosum Ulcers.
CONCLUSIONS: The new possibilities offered by NPWT with nonadhesive foam and regenerative medicine are typically affordable, effective, safe, and painless for the patient. Both methods were noninvasive, did not accelerated the pathergy phenomenon, and showed a potential for faster healing of PG ulcers. PMID: 32155124 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - March 11, 2020 Category: General Medicine Tags: Wounds Source Type: research

Treating Wounds With an Avascular Component With a Dermal Regenerative Template.
CONCLUSIONS: This literature review and retrospective study confirm the DRT is a viable option to provide vascularized coverage over wounds with avascular components. This study suggests the DRT is more reliable in wounds with less than 1.9% avascular tissues and less successful in chronic wounds. PMID: 32155125 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - March 11, 2020 Category: General Medicine Tags: Wounds Source Type: research

Amniotic Suspension Allograft and Fetal Bovine Acellular Dermal Matrix to Treat Complex, Acute, Full-thickness Wounds: A Retrospective Analysis of Safety and Treatment Efficacy.
CONCLUSIONS: In a small but challenging population including a high number of patients with comorbidities and exposed bone or tendon, it was found that ASA delivery, along with a dermal matrix, was successful in treating large, complex, acute wounds. PMID: 32155126 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - March 11, 2020 Category: General Medicine Tags: Wounds Source Type: research

Clinical and Economic Impact of a Two-layer Compression System for the Treatment of Venous Leg Ulcers: A Systematic Review.
CONCLUSIONS: Based on these findings, 2LBA may result in lower treatment costs and better ulcer healing and HRQoL compared with other multicomponent therapies, especially in patients with newly diagnosed VLUs. However, further high-quality research is needed, especially for outcomes such as slippage and bandage wear time. PMID: 32155127 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - March 11, 2020 Category: General Medicine Tags: Wounds Source Type: research

Infection and Inflammation in the Wound Environment: Addressing Issues of Delayed Wound Healing With Advanced Wound Dressings.
Authors: Gabriel A, Barrett C, Cullen B, Hodges D, Lee W, Snyder R, Speyrer M, Suski M, Dick S, Thomason HA, Treadwell T Abstract Impaired wound healing is estimated to affect about 2% of the US population, and a major goal of health care providers (HCPs) is to better understand delayed healing so they can effectively choose advanced wound dressings to manage these wounds. However, there are estimated to be more than 3000 dressing options available, making dressing selection an overwhelming burden. An expert panel of 7 HCPs experienced in diverse medical disciplines and 3 scientists convened to discuss the use of 2...
Source: Wounds - December 28, 2019 Category: General Medicine Tags: Wounds Source Type: research

Comparative Effectiveness of Two Collagen-containing Dressings: Oxidized Regenerated Cellulose (ORC)/Collagen/Silver-ORC Dressing Versus Ovine Collagen Extracellular Matrix.
CONCLUSIONS: According to this comparative effectiveness study using real world data, ORC/collagen/silver-ORC dressing appears to afford improved healing and reduced time to granulation relative to ovine collagen ECM dressing. PMID: 31876511 [PubMed - in process] (Source: Wounds)
Source: Wounds - December 28, 2019 Category: General Medicine Tags: Wounds Source Type: research

Biological Mesh Combined With Topical Negative Pressure Therapy in Complex Abdominal Wounds: A Short Series and a Review of the Literature.
CONCLUSIONS: From these cases and the review of the literature, the authors believe TNP can be applied on a biological mesh with effectiveness in improving the treatment of the CAWs without relevant risk to the patient or biological mesh. PMID: 31876512 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - December 28, 2019 Category: General Medicine Tags: Wounds Source Type: research