Use of a Novel Foam Dressing With Negative Pressure Wound Therapy and Instillation: Recommendations and Clinical Experience.
Authors: Kim PJ, Applewhite A, Dardano AN, Fernandez L, Hall K, McElroy E, Mendez-Eastman S, Obst MA, Thomas C, Waddell L, Wirth G, Téot L Abstract A new reticulated open-cell foam dressing with through holes (ROCF-CC) has been introduced to assist with wound cleansing by removing thick wound exudate and infectious materials during neg- ative pressure wound therapy with instillation. Due to the limited published evidence supporting use of ROCF-CC dressings with negative pressure wound therapy with instillation and dwell time (NPWTi-d), clinicians have been relying on practical application experience to gain ...
Source: Wounds - May 5, 2018 Category: General Medicine Tags: Wounds Source Type: research

Comparison of DNA Damage and Apoptosis Induced By Silver Nanoparticle-containing Dressing Materials During Wound Healing.
CONCLUSIONS: Dressing materials containing AgNP have an antimicrobial effect. However, the authors observed that some AgNP dressings induced DNA damage and apoptosis. Although AgNP dressings did not cause significant acute apoptotic effects, they should be examined for cytotoxic effects in chronic wounds and should be used with caution when treating chronic wounds and those with low bacteria counts. PMID: 29718810 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - May 3, 2018 Category: General Medicine Tags: Wounds Source Type: research

A Total Offloading Foot Brace for Treatment of Diabetic Foot Ulcers: Results From a Halted Randomized Controlled Trial.
CONCLUSIONS: The total offloading foot brace minimizes plantar pressure, allowing for early healing of DFUs, and optimizations in brace design may enhance healing of plantar DFUs. PMID: 29718811 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - May 3, 2018 Category: General Medicine Tags: Wounds Source Type: research

Safety and Efficacy of an Autologous Blood Clot Product in the Management of Texas 1A or 2A Neuropathic Diabetic Foot Ulcers: A Prospective, Multicenter, Open Label Pilot Study.
CONCLUSIONS: This study demonstrates that the blood clot product is safe and efficacious for treating DFUs. PMID: 29718812 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - May 3, 2018 Category: General Medicine Tags: Wounds Source Type: research

Efficacy of Honeydew Honey and Blossom Honey on Full-thickness Wound Healing in Mice.
This study compares the effects of honeydew honey with those of blossom honey. MATERIALS AND METHODS: A total of 140 mice were divided into 2 control groups, which received either a hydrocolloid dressing (HCD; n = 22) or gauze (n = 22), and 4 experimental groups: honeydew honey (n = 23), Acacia honey (n = 23), Manuka honey (n = 22), and Japanese Pharmacopoeia honey (n = 28). Two circular full-thickness wounds were made and measured for 14 days. Each wound in the experimental groups was treated with 0.1 mL of honey and covered with gauze. Dressings in the control and experimental groups were changed daily. RESULTS: ...
Source: Wounds - May 3, 2018 Category: General Medicine Tags: Wounds Source Type: research

Use of Viable Cryopreserved Umbilical Tissue for Soft Tissue Defects in Patients With Gas Gangrene: A Case Series.
CONCLUSIONS: The positive clinical outcomes indicate that vCUT may be an effective aid as an intraoperative application to cover wounds following aggressive debridement in the presence of gas gangrene. PMID: 29718818 [PubMed - in process] (Source: Wounds)
Source: Wounds - May 3, 2018 Category: General Medicine Tags: Wounds Source Type: research

Understanding Diabetic Induction of Cellular Senescence: A Concise Review.
CONCLUSIONS: Overall, both devices elicited similar progression of healing by 8 weeks. The SCBS produced a deeper thermal effect in a shorter treatment time and improved myofiber regeneration compared with ES and had an equivalent overall course of healing. PMID: 29718819 [PubMed - in process] (Source: Wounds)
Source: Wounds - May 3, 2018 Category: General Medicine Tags: Wounds Source Type: research

Characteristics of Surgical Site Infection Following Colorectal Surgery in a Tertiary Center: Extended-spectrum β-Lactamase-producing Bacteria Culprits in Disease.
CONCLUSIONS: More than one-third of the wound infections were due to ESBL-producing pathogens, which were resistant to the antibiotic prophylaxis given. Inappropriate antibiotic usage can delay postoperative recovery. High-risk patients for ESBL colonization may benefit from preoperative screening based on an established protocol. The cost effectiveness of an ESBL screening program needs to be further studied. PMID: 29718820 [PubMed - in process] (Source: Wounds)
Source: Wounds - May 3, 2018 Category: General Medicine Tags: Wounds Source Type: research

Synergism of Therapies After Postoperative Autograft Failure in a Patient With Melanoma of the Foot Misdiagnosed as a Pressure Ulcer.
CONCLUSIONS: Physicians must remain highly cautious of ulcerated lesions of the foot and may consider epidermal fractional skin grafting as a valid therapeutic option in case of postsurgical wounds resulting from wide local excision of malignant melanomas. PMID: 29718821 [PubMed - in process] (Source: Wounds)
Source: Wounds - May 3, 2018 Category: General Medicine Tags: Wounds Source Type: research

Remote Temperature Monitoring in Diabetic Foot Ulcer Detection.
CONCLUSIONS: The findings of this case series are consistent with literature supporting the use of RTM for high-risk patients. PMID: 29718822 [PubMed - in process] (Source: Wounds)
Source: Wounds - May 3, 2018 Category: General Medicine Tags: Wounds Source Type: research

Wound Bed Preparation for Capsulectomy Using a Hydrosurgery System.
CONCLUSIONS: In the case reported herein, the hydrosurgery system proved beneficial for capsulectomy. PMID: 29718823 [PubMed - in process] (Source: Wounds)
Source: Wounds - May 3, 2018 Category: General Medicine Tags: Wounds Source Type: research

Application of Viable Cryopreserved Human Placental Membrane Grafts in the Treatment of Wounds of Diverse Etiologies: A Case Series.
CONCLUSIONS: Viable CHPM is an effective treatment modality for wounds of diverse etiologies and shows better results than have been previously published with standard of care. In patients with PGUs, medical optimization and close management of comorbidities is essential in achieving optimal results. PMID: 29584601 [PubMed - in process] (Source: Wounds)
Source: Wounds - March 28, 2018 Category: General Medicine Tags: Wounds Source Type: research

Effect of a New Purified Collagen Matrix With Polyhexamethylene Biguanide on Recalcitrant Wounds of Various Etiologies: A Case Series.
CONCLUSIONS: This case series demonstrated that PCMP along with good wound care supported both wound closure and improvements in wound bed condition and area reduction on recalcitrant, nonhealing wounds of various etiologies. PMID: 29584602 [PubMed - in process] (Source: Wounds)
Source: Wounds - March 28, 2018 Category: General Medicine Tags: Wounds Source Type: research

Evidence Corner: The Challenges of Healing Arterial Ulcers.
Authors: Bolton L PMID: 29584603 [PubMed - in process] (Source: Wounds)
Source: Wounds - March 28, 2018 Category: General Medicine Tags: Wounds Source Type: research

Do Not Limit Where Ulcer Debridements Can Be Performed!
Authors: Lehrman JD Abstract Medicare is a national program administered on a local level by Medicare Administrative Contractors (MACs). This brief report focuses on the potentially negative outcomes that may ensue as a result of MACs limiting the place of service for ulcer debridement. With the information included herein, the hope is that this problem can be addressed by all parties involved in wound care, including medical directors at these MACs, to remove this limitation impacting patient care. PMID: 29584604 [PubMed - in process] (Source: Wounds)
Source: Wounds - March 28, 2018 Category: General Medicine Tags: Wounds Source Type: research

Evaluating the Impact of a Patient-centered Remote Monitoring Program on Adherence to Negative Pressure Wound Therapy.
CONCLUSIONS: This evaluation suggests there is an ability to influence patient adherence through active engagement, potentially improving outcomes and reducing wound costs. PMID: 29584605 [PubMed - in process] (Source: Wounds)
Source: Wounds - March 28, 2018 Category: General Medicine Tags: Wounds Source Type: research

Hereditary Sensory and Autonomic Neuropathy Presenting With Mutilating Trophic Ulcers.
Authors: Mathur DK, Prakash C, Bhargava P, Paliwal V, Mathur K Abstract Two siblings, a 19-year-old woman and an 18-year-old man, born to apparently normal parents of second-degree consanguineous marriage, presented to the Department of Dermatology, Sawai Man Singh Medical College Hospital, Jaipur, India, with recurrent skin ulcers of the hands and feet since early childhood. The ulcers were spontaneous, slow to heal, and caused deformities. On initial examination, they were found to have distal sensory loss, predominantly to pain and temperature. The patients were diagnosed with hereditary sensory and autonomic ne...
Source: Wounds - March 28, 2018 Category: General Medicine Tags: Wounds Source Type: research

Calcinosis Cutis and Negative Pressure Wound Therapy as Adjuncts to Surgical Management: Case Report and Review of the Literature.
Authors: Radu F, Nishiaoki M, Louis MA Abstract Calcinosis cutis (CC), or calcium deposition in soft tissue, can cause significant morbidity associated with arthralgias and ulceration. This condition has an elusive pathophysiology and is often associated with autoimmune disorders, significantly impacting the disease burden. The clinical presentation of CC varies, and there is no gold standard treatment modality. The case of a 50-year-old woman with scleroderma and a rare presentation of milky drainage of a left hip ulcer secondary to underlying CC that was treated successfully with surgery and negative pressure wou...
Source: Wounds - March 28, 2018 Category: General Medicine Tags: Wounds Source Type: research

Utilization of a Viable Human Amnion Membrane Allograft in Elderly Patients With Chronic Lower Extremity Wounds of Various Etiologies.
CONCLUSIONS: Successful closure of wounds indicates the use of vHAMA may be beneficial for treatment of chronic wounds in elderly patients with comorbidities. PMID: 29584608 [PubMed - in process] (Source: Wounds)
Source: Wounds - March 28, 2018 Category: General Medicine Tags: Wounds Source Type: research

Profile and Antibiotic Susceptibility of Bacteria Isolates in Burn Patients Hospitalized in a Moroccan Hospital: A Cross-sectional Study.
CONCLUSIONS: The profile of this bacterial ecology shows there are resistant species requiring frequent use of second-line antibiotics and strengthening of aseptic procedures in burn treatments. PMID: 29521639 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - March 11, 2018 Category: General Medicine Tags: Wounds Source Type: research

A Randomized Controlled Study Evaluating the Clinical Benefits of a Cellulose Acetate Mesh Coated with a Soft Silicone in the Management of Acute Wounds.
CONCLUSIONS: This study demonstrated that CAM coated with a soft silicone performed as well as the FPN contact layer in minimizing dressing adherence, time to complete reepithelialization, and patient tolerance. PMID: 29521640 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - March 11, 2018 Category: General Medicine Tags: Wounds Source Type: research

Clinical Assessment of a Biofilm-disrupting Agent for the Management of Chronic Wounds Compared With Standard of Care: A Therapeutic Approach.
Authors: Kim D, Namen Ii W, Moore J, Buchanan M, Hayes V, Myntti MF, Hakaim A Abstract OBJECTIVE: The authors study the use of a biofilm-disrupting wound gel designed for wound management to determine if disrupting chronic wound biofilm would be therapeutically efficacious. MATERIALS AND METHODS: This prospective, randomized, open-label clinical trial was performed from September 2014 through March 2016. Forty-three patients (22 experimental, 21 control) with chronic, recalcitrant wounds were randomized to a 12-week treatment with a biofilm-disrupting wound gel (experimental) or a broad-spectrum antimicrobial o...
Source: Wounds - March 11, 2018 Category: General Medicine Tags: Wounds Source Type: research

Assessment of 16-month Sequelae Due to Dog Bites Originally Studied in a French Multicenter Survey from 2009 to 2011.
This study aims to describe the sequelae 16 months after dog bites. MATERIALS AND METHODS: Following an initial epidemiological study on the severity of 485 dog bites carried out in 8 hospital emergency departments between May 1, 2009, and June 30, 2010, a second study investigating sequelae 16 months after the bite was conducted among 298 patients between September 2010 and December 2011. Data concerning patients' sequelae were collected by telephone or email. RESULTS: Almost half of respondents (47%) reported sequelae; of those patients, most of these reports were aesthetic (9/10). There were more sequelae when t...
Source: Wounds - March 11, 2018 Category: General Medicine Tags: Wounds Source Type: research

Clinic-based Debridement of Chronic Ulcers Has Minimal Impact on Bacteria.
CONCLUSIONS: There is no statistically significant difference between the predebridement versus postdebridement semiquantitative culture results or a detectable pattern of change for the most common bacterial species encountered. These results suggest little impact of clinic-based sharp debridement on bacteria. PMID: 29521643 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - March 11, 2018 Category: General Medicine Tags: Wounds Source Type: research

Cost-effectiveness Analysis of Silver Delivery Approaches in the Management of Partial-thickness Burns.
This study sought to determine the cost effectiveness of the newer silver dressings using clinical data from an indirect treatment comparison using silver sulfadiazine as the baseline. MATERIALS AND METHODS: A decision analytic model was developed from a US payer's perspective for burn patients with a total body surface area of
Source: Wounds - March 11, 2018 Category: General Medicine Tags: Wounds Source Type: research

Laparoscopy-assisted Chimeric Peritoneal-deep Inferior Epigastric Perforator Flap for Reconstruction of Hand and Foot.
CONCLUSIONS: The laparoscopy-assisted chimeric peritoneal-DIEP flap is useful for reconstructing defects of the hand and foot with exposed tendons. PMID: 29481328 [PubMed - in process] (Source: Wounds)
Source: Wounds - February 28, 2018 Category: General Medicine Tags: Wounds Source Type: research

Topical Nystatin Treatment for Candida Infection Following Wound Reconstruction.
CONCLUSIONS: The authors propose this simple, nontoxic, and economic topical treatment for wounds and skin grafts with positive Candida cultures. PMID: 29481329 [PubMed - in process] (Source: Wounds)
Source: Wounds - February 28, 2018 Category: General Medicine Tags: Wounds Source Type: research

Total Contact Cast Use in Patients With Peripheral Arterial Disease: A Case Series and Systematic Review.
CONCLUSIONS: Vascular evaluation, individual risk/benefit analysis, close follow-up, and patient education are essential components of TCC use in these patients. Repeat vascular evaluation is recommended if the wound fails to progress towards resolution with TCC use. PMID: 29481330 [PubMed - in process] (Source: Wounds)
Source: Wounds - February 28, 2018 Category: General Medicine Tags: Wounds Source Type: research

Editorial Message: Are We Already Too Late?
Authors: Treadwell T PMID: 29481331 [PubMed - in process] (Source: Wounds)
Source: Wounds - February 28, 2018 Category: General Medicine Tags: Wounds Source Type: research

Cost-minimization Analysis of Negative Pressure Wound Therapy in Long-term Care Facilities.
CONCLUSIONS: Long-term care facilities can potentially accrue significant cost savings by using sNPWT instead of tNPWT on a majority of eligible wounds. PMID: 29481332 [PubMed - in process] (Source: Wounds)
Source: Wounds - February 28, 2018 Category: General Medicine Tags: Wounds Source Type: research

Pyoderma Gangrenosum of the Scalp: A Rare Clinical Variant.
Authors: Gupta AS, Nunley JR, Feldman MJ, Ortega-Loayza AG Abstract Pyoderma gangrenosum (PG) is a rare, neutrophil-predominant dermatosis that usually presents as a papule or pustule and progresses into a painful ulcer. Clinical and histopathological features are nonspecific, making PG a challenging condition to diagnose. Lesions may occur anywhere on the body; however, the lower extremity is the most common location. Solitary lesions in atypical locations such as the scalp are uncommon, making this clinical variant especially difficult to recognize and diagnose. Although the clinical features and subsequent manag...
Source: Wounds - February 28, 2018 Category: General Medicine Tags: Wounds Source Type: research

Martorell Hypertensive Ischemic Ulcer Successfully Treated With Punch Skin Grafting.
Authors: Conde Montero E, Guisado Muñoz S, Pérez Jerónimo L, Peral Vazquez A, Montoro Lopez JJ, Hocajada Reales C, Baniandrés Rodriguez O, de la Cueva Dobao P Abstract Martorell hypertensive ischemic ulcer can be a real clinical and therapeutic challenge. Controversy exists regarding both the underlying triggers of the disease and the type of treatment that should be established. Early skin grafting has been suggested as an effective treatment to enhance pain reduction and wound healing in these patients. The authors present the case of a 68-year-old woman with well-controlled hypertensi...
Source: Wounds - February 28, 2018 Category: General Medicine Tags: Wounds Source Type: research

Efficacy of a Nanofabricated Electrospun Wound Matrix in Treating Full-thickness Cutaneous Wounds in a Porcine Model.
CONCLUSIONS: The nanofiber wound matrix is an effective wound healing material that may offer a unique alternative in the treatment of challenging refractory wounds. PMID: 29481335 [PubMed - in process] (Source: Wounds)
Source: Wounds - February 28, 2018 Category: General Medicine Tags: Wounds Source Type: research

Why Do Wounds Itch?
Authors: Lerner E Abstract Everyone has experienced itch. It might simply be the nuisance of a mosquito bite or a transient itch on the scalp that is relieved by a simple scratch. For wounds such as venous ulcers, itch may be present but is usually mild. For some of the 40% of people with neuropathic itch or pain that can develop and persist following mastectomy, itch can be overwhelming, intractable, not widely appreciated by the medical community, and poorly responsive to current treatment regimens. Why are some wounds in some patients itchy whereas seemingly equivalent ones in the same or other patients not? Why...
Source: Wounds - February 8, 2018 Category: General Medicine Tags: Wounds Source Type: research

Descriptors for Itch Related to Chronic Wounds.
CONCLUSIONS: This list of descriptors for wound-related itch can be tested further for clinical use and for research purposes when wound-related itch is being explored. PMID: 29406292 [PubMed - in process] (Source: Wounds)
Source: Wounds - February 8, 2018 Category: General Medicine Tags: Wounds Source Type: research

Itching for Knowledge About Wound and Scar Pruritus.
Authors: Parnell LKS Abstract Chronic itch continues to be a problem that plagues millions of humans and animals. Pruritus has a negative impact on patient quality of life and many patients experience sleep deprivation, anxiety, and depression, similar to patients with chronic pain. This review provides an overview of clinical pruritus research with special emphasis on itch that wound care providers may see. In addition, the need for using multifactorial questionnaires for better research in pruritus is summarized. Similarities and differences in itch characteristics, triggers, and relievers in various patient popu...
Source: Wounds - February 8, 2018 Category: General Medicine Tags: Wounds Source Type: research

Evidence Corner: Taking Itch Seriously.
Authors: Bolton LT Abstract Dear Readers, Itching (pruritus) of a wound, scar, or dermatologic disorder can negatively impact a patient's quality of life, resulting in injurious scratching1 or impeded rehabilitation.2 Like pain, itch can cause the su erer to lose sleep and appetite or even consider suicide.3,4 Clinical measures of pruritus have proved reliable and valid in individuals with burn wounds, dermatologic conditions, or urticaria5-7 or resulting scars,2 allowing studies to clarify its impact on human experience and compare the e ects of interventions to reduce itching. This Evidence Corner explores the e ...
Source: Wounds - February 8, 2018 Category: General Medicine Tags: Wounds Source Type: research

Postburn Itch: A Review of the Literature.
Authors: Nedelec B, LaSalle L Abstract The problem of postburn itch has been underevaluated and undertreated in the past. However, recently published data have expanded the evidence base, which provides clinicians and their patients with new evaluation and treatment options that can help reduce and potentially eliminate the prolonged distress experienced by burn survivors faced with postburn itch. Although a gold standard evaluation method has not yet been agreed upon, there are a number of tools that have been published that clinicians can use for assessment. Epidemiological evidence has confirmed that the vast ma...
Source: Wounds - February 8, 2018 Category: General Medicine Tags: Wounds Source Type: research

Abdominal Catastrophe in Crohn's Disease Surgery.
CONCLUSIONS: Anastomotic dehiscence after intestinal resection can lead to an abdominal catastrophe. Severe peritonitis with enteric fistulas and an open abdomen demands a multidisciplinary approach. Negative pressure wound therapy and nutritional support are key treatments. In these patients, stoma closure and abdominal wall reconstruction after recovery from the acute event represents another surgical challenge. PMID: 29406296 [PubMed - in process] (Source: Wounds)
Source: Wounds - February 8, 2018 Category: General Medicine Tags: Wounds Source Type: research

Sacral Pressure Ulcer-induced Fournier's Gangrene Extending to the Retroperitoneum: A Case Report.
CONCLUSIONS: The authors consider continuous irrigation combined with negative pressure wound therapy as extremely useful for patients with FG in whom sufficient debridement cannot be performed. PMID: 29406297 [PubMed - in process] (Source: Wounds)
Source: Wounds - February 8, 2018 Category: General Medicine Tags: Wounds Source Type: research

Effects of Omega-3 Fatty Acids Against Chemotherapy-induced Mucositis: A Double-blind Randomized Clinical Trial.
CONCLUSIONS: Omega-3 fatty acids are a safe, effective method for preventing and treating oral mucositis in patients receiving mucotoxic cancer chemotherapy. PMID: 29324423 [PubMed - in process] (Source: Wounds)
Source: Wounds - January 13, 2018 Category: General Medicine Tags: Wounds Source Type: research

Larval Therapy for Chronic Cutaneous Ulcers: Historical Review and Future Perspectives.
Authors: Raposio E, Bortolini S, Maistrello L, Grasso DA Abstract Cutaneous ulcers tend to become chronic and have a profound impact on quality of life. These wounds may become infected and lead to greater morbidity and even mortality. In the past, larvae (ie, maggots) of certain common flies (Lucilia sericata and Lucilia cuprina) were considered useful in ulcer management because they only remove necrotic tissue while promoting healthy tissue in the wound bed, thus helping wounds heal faster. Recently, maggots from several other fly species (Calliphora vicina, Calliphora vomitoria, Phormia regina, Chrysomya albice...
Source: Wounds - January 13, 2018 Category: General Medicine Tags: Wounds Source Type: research

Comparison of a Saline-coupled Bipolar Sealer Versus Traditional Electrosurgery in a Porcine Model of Chronic Wound Healing.
CONCLUSIONS: Overall, both devices elicited similar progression of healing by 8 weeks. The SCBS produced a deeper thermal effect in a shorter treatment time and improved myofiber regeneration compared with ES and had an equivalent overall course of healing. PMID: 29324425 [PubMed - in process] (Source: Wounds)
Source: Wounds - January 13, 2018 Category: General Medicine Tags: Wounds Source Type: research

A Sweet Solution: The Use of Medical-grade Honey on Oral Mucositis in the Pediatric Oncology Patient.
CONCLUSIONS: Leptospermum honey paste proved to be effective in all participating patients. PMID: 29324426 [PubMed - in process] (Source: Wounds)
Source: Wounds - January 13, 2018 Category: General Medicine Tags: Wounds Source Type: research

Lemons in the Arizona Sunshine: The Effects of Furocoumarins Leading to Phytophotodermatitis and Burn-like Injuries.
CONCLUSIONS: Burn-like lesions caused by furocoumarins after cutaneous absorption and UV-A exposure are known clinical entities in Arizona. The sequential progression from erythema to blisters equivalent to second-degree burn-like lesions to cutaneous hyperpigmentation is a well-described clinical triad. Meticulous wound care and pain control for the treatment of these burn-like lesions are essential as is the need for the wound care specialist to be well versed on this topic to quickly identify the etiology of the injury, thereby avoiding misdiagnosing the patient with nonaccidental traumatic injuries. PMID: 29324427 ...
Source: Wounds - January 13, 2018 Category: General Medicine Tags: Wounds Source Type: research

Malignant Transformation of a Site of Prior Diabetic Foot Ulceration to Verrucous Carcinoma: A Case Report.
Authors: Priesand SJ, Holmes CM Abstract The case of a 62-year-old Caucasian man with type 1 diabetes who developed malignant transformation of an area of prior diabetic foot ulceration (DFU) is reported. He had significant hallux valgus deformity, multiple episodes of healing and breakdown, and eventual transformation to verrucous carcinoma (VC). This case report highlights the malignant transformation of a site of previous DFU to VC, which, to the best of the authors' knowledge, has not yet been described in the literature. There has been little research performed that examines VC in the diabetic population. This...
Source: Wounds - January 13, 2018 Category: General Medicine Tags: Wounds Source Type: research

A Pilot Clinical Study of a Safe and Efficient Stool Management System in Patients With Fecal Incontinence.
CONCLUSIONS: This study, along with pilot clinical findings, suggests that this technology minimizes the pressure exerted on the rectal wall. There were significantly fewer forces against the anorectal mucosa compared with the cuff-based catheter during insertion, withdrawal, and accidental expulsion. PMID: 29324429 [PubMed - in process] (Source: Wounds)
Source: Wounds - January 13, 2018 Category: General Medicine Tags: Wounds Source Type: research

Low-intensity Exercise Accelerates Wound Healing in Diabetic Mice.
CONCLUSIONS: In this preliminary investigation, low-intensity exercise accelerated wound healing rates in diabetic mice but high-intensity exercise did not. Future studies should investigate the mechanisms behind this effect and evaluate different intensities of exercise on wound healing in humans with type 2 diabetes. PMID: 29166252 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - November 24, 2017 Category: General Medicine Tags: Wounds Source Type: research

Hepatitis C Virus: Patients' Risk Factors and Knowledge in an Urban Clinic Providing Wound Care.
CONCLUSIONS: This urban clinic had patients with multiple HCV risk factors; they often lacked HCV screening and/or referral for treatment. Their HCV knowledge was generally low. As a major public health problem that could impact wound healing, wound care practitioners should ask patients about their HCV status, encourage HCV screening and care, and provide HCV information. PMID: 29166253 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - November 24, 2017 Category: General Medicine Tags: Wounds Source Type: research

Proactive and Early Aggressive Wound Management: A Shift in Strategy Developed by a Consensus Panel Examining the Current Science, Prevention, and Management of Acute and Chronic Wounds.
Authors: Bohn GA, Schultz GS, Liden BA, Desvigne MN, Lullove EJ, Zilberman I, Regan MB, Ostler M, Edwards K, Arvanitis GM, Hartman JF Abstract Normal wound healing is accomplished through a series of well-coordinated, progressive events with overlapping phases. Chronic wounds are described as not progressing to healing or not being responsive to management in a timely manner. A consensus panel of multidisciplinary wound care professionals was assembled to (1) educate wound care practitioners by identifying key principles of the basic science of chronic wound pathophysiology, highlighting the impact of metalloprotei...
Source: Wounds - November 24, 2017 Category: General Medicine Tags: Wounds Source Type: research