Surgical Application of Viable Cryopreserved Placental Membrane for the Treatment of Chronic Wounds in 12 High-risk Patients.
The objective of this retrospective case series is to evaluate the safety and efficacy of a viable cryopreserved placental membrane (vCPM) in 12 patients with 16 wounds of mixed etiologies when surgically debrided and augmented with vCPM 1 time, followed by standard of care (nonadherent dressing, gauze, and compression) until healed. The results of this case series demonstrate that the surgical application of vCPM can be used as an alternative treatment for high-risk patients with chronic lower extremity wounds. PMID: 30418161 [PubMed - in process] (Source: Wounds)
Source: Wounds - November 13, 2018 Category: General Medicine Tags: Wounds Source Type: research

Platelet-rich Plasma and Other Hemocomponents in Veterinary Regenerative Medicine.
Authors: Tambella AM, Martin S, Cantalamessa A, Serri E, Attili AR Abstract Platelet-rich plasma, platelet-rich fibrin, fibrin glue, and platelet lysate are the most widely used nontransfusional hemocomponents that, as biological and therapeutic aids, enhance the physiological reactions after an injury to facilitate the repair and regeneration processes. Recently, this type of therapy also has significantly expanded in veterinary medicine. Due to many similarities, the animal patient could be a good reference as a study model for humans, especially for chronic and difficult-to-heal injuries. This review discusses t...
Source: Wounds - November 13, 2018 Category: General Medicine Tags: Wounds Source Type: research

Time to Abandon Antimicrobial Approaches in Wound Healing: A Paradigm Shift.
Authors: Sams-Dodd J, Sams-Dodd F Abstract Antimicrobial approaches (eg, antibiotics and antiseptics) have been used for decades in the treatment of infected wounds, ulcers, and burns. However, an increasing number of meta-analyses have raised questions regarding the therapeutic value of these approaches. Newer findings show that the body actively hosts an ecosystem of bacteria, fungi, viruses, and mites on its outer surfaces, known as the microbiome, as part of its defense against pathogens. Antimicrobials would disrupt this system and thereby work against the strategy the body has chosen. Recently, a new technolo...
Source: Wounds - November 13, 2018 Category: General Medicine Tags: Wounds Source Type: research

Volatile Organic Compounds of Malignant Breast Cancer Wounds: Identification and Odors.
CONCLUSIONS: This study suggests the bacteria present in wounds may be responsible for odors. In addition, these findings could pave the way to engineer new types of dressings and to develop an evaluation method to assess their efficiency both quantitatively and qualitatively as well as improve quality of palliative care and comfort for women with malignant wounds. PMID: 30380523 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - November 2, 2018 Category: General Medicine Tags: Wounds Source Type: research

Dehydrated Amnion/Chorion Improves Achilles Tendon Repair in a Diabetic Animal Model.
CONCLUSIONS: This study highlights a promising treatment option for this challenging clinical population. PMID: 30372415 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - October 31, 2018 Category: General Medicine Tags: Wounds Source Type: research

Patient-controlled Analgesia and Postoperative Pressure Ulcer: A Meta-analysis of Observational Studies.
CONCLUSIONS: This meta-analysis shows PCA may be associated with an increased risk of postoperative pressure ulcer, especially after caesarean section. More evidence-based studies on this research field are needed to draw a firmer conclusion. PMID: 30372416 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - October 31, 2018 Category: General Medicine Tags: Wounds Source Type: research

Lower Limb Nonhealing Ulcers Associated With Chronic Diabetes: A Case Series.
CONCLUSIONS: These therapeutic approaches alleviated local inflammatory damage and adverse systemic reactions, which is an important basis for further treatment (eg, anti-infection treatment, blood glucose reduction, blood pressure control, organ function improvement, circulation promotion, and nutritional support). PMID: 30372417 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - October 31, 2018 Category: General Medicine Tags: Wounds Source Type: research

Laser-assisted Fluorescent Angiography to Assess Tissue Perfusion in the Setting of Traumatic Elbow Dislocation.
CONCLUSIONS: In conjunction with plastic surgeons, the orthopaedic team utilized LAFA for debridement that led to both a successful wound repair and skin grafting procedure. PMID: 30312970 [PubMed - in process] (Source: Wounds)
Source: Wounds - October 14, 2018 Category: General Medicine Tags: Wounds Source Type: research

Diagnosis and Treatment of Invasive Aspergillus fumigatus Wound Infection Following Subtotal Colectomy for Perforated Toxic Megacolon in an Immunosuppressed Patient.
CONCLUSIONS: This case highlights the importance of early and accurate identification, debridement, and systemic antifungals to prevent widespread infection. With changes in antifungal care over recent years, engaging infectious disease physicians during treatment is recommended. PMID: 30312971 [PubMed - in process] (Source: Wounds)
Source: Wounds - October 14, 2018 Category: General Medicine Tags: Wounds Source Type: research

Fully Synthetic Bioengineered Nanomedical Scaffold in Chronic Neuropathic Foot Ulcers.
CONCLUSIONS: The nanomedical scaffold successfully reduced the ulcer depths, stimulated granulation tissue while preventing necrosis, and helped the wounds remain infection free. The outcome of this case series suggests a fully synthetic bioengineered nanomedical scaffold can be used as an alternative to human or animal extracellular matrix in chronic, hard-to-heal neuropathic ulcers. PMID: 30312972 [PubMed - in process] (Source: Wounds)
Source: Wounds - October 14, 2018 Category: General Medicine Tags: Wounds Source Type: research

Key Cell Functions are Modulated by Compression in an Animal Model of Hypertrophic Scar.
CONCLUSIONS: Compression modulates transcription and affects multiple biological functions associated with an improved scar appearance. PMID: 30304713 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - October 13, 2018 Category: General Medicine Tags: Wounds Source Type: research

Outcomes in Fournier's Gangrene Using Skin and Soft Tissue Sparing Flap Preservation Surgery for Wound Closure: An Alternative Approach to Wide Radical Debridement.
CONCLUSIONS: To the best of the authors' knowledge, this is the largest case series reported in the literature using skin and soft tissue sparing surgery for wound closure of a FG NSTI. PMID: 30299266 [PubMed - in process] (Source: Wounds)
Source: Wounds - October 11, 2018 Category: General Medicine Tags: Wounds Source Type: research

Unusual Presentation of Deep Tissue Injuries: A Case Series.
Authors: Wilson M, Simman R Abstract Deep tissue injuries (DTIs) are the manifestation of multiple layers of tissue necrosis and are often secondary to chronic mechanical stress to an area of bony prominence. The prevalence of these injuries among the chronically ill and patients in long-term care require a strong understanding of their etiology and a highly sensitive identification algorithm. Although the National Pressure Ulcer Advisory Panel (NPUAP) has released new guidelines with accurate descriptions as to how these injuries present, there is a significant segment of patients that present atypically and, as s...
Source: Wounds - October 11, 2018 Category: General Medicine Tags: Wounds Source Type: research

Operative Management of Abdominal Wound Dehiscence: Outcomes and Factors Influencing Time to Healing in Patients Undergoing Surgical Debridement With Primary Closure.
CONCLUSIONS: Operative debridement and closure of abdominopelvic wound dehiscence through a multidisciplinary team approach with plastic surgery results in expeditious wound healing with minimal complications, and it may be safer and more cost effective than healing by secondary intention. PMID: 30289765 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - October 7, 2018 Category: General Medicine Tags: Wounds Source Type: research

Development of a Manual for the Prevention and Treatment of Skin Tears.
CONCLUSIONS: A content-validated manual for the prevention and treatment of skin tears was created to guide nursing professionals in the management of patients with skin tears, which contributes to the identification of risk factors and development of preventive measures. PMID: 30260318 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - September 28, 2018 Category: General Medicine Tags: Wounds Source Type: research

Efficacy of Silver-based Gel Compared With Fusidic Acid Cream in Topical Treatment Following Trichloroacetic Acid Facial Skin Peeling: A Pilot Study.
CONCLUSIONS: Comparing between the groups treated with silver-based gel and fusidic acid cream, the authors found no inferiority in the outcomes or the prevalence of any complaints, and a superior effect on the prevention of wound itch using a silver-based gel. PMID: 30260319 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - September 28, 2018 Category: General Medicine Tags: Wounds Source Type: research

Durability of an Advanced Skin Protectant Compared With Other Commercially Available Products in Healthy Human Volunteers.
Authors: Mathisen M, Grove G, Houser T, Bernatchez SF Abstract BACKGROUND: A new skin protectant with improved adhesion to denuded skin and resistance to wash off has been developed to protect skin from incontinence-associated dermatitis (IAD) or general loss of skin integrity. OBJECTIVE: This controlled, randomized, prospective, open-label study determines the durability of the new protectant when applied to intact skin in 21 healthy human volunteers and compares it to 3 other products used for similar clinical indications. MATERIALS AND METHODS: Eight 0.75-in circles of black carbon pigment were applied t...
Source: Wounds - September 27, 2018 Category: General Medicine Tags: Wounds Source Type: research

Open-label Extension Phase of a Chronic Diabetic Foot Ulcer Multicenter, Controlled, Randomized Clinical Trial Using Cryopreserved Placental Membrane.
CONCLUSIONS: These results corroborate the benefits of this CPM combined with SWC over SWC alone for chronic DFUs previously reported for the blinded randomized phase of the trial, which directly relate to lower health care costs. PMID: 30256747 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - September 27, 2018 Category: General Medicine Tags: Wounds Source Type: research

Perioperative Nutritional Support With Beta-hydroxy-beta-methylbutyrate, Arginine, and Glutamine in Surgery for Abdominal Malignancies.
CONCLUSIONS: The incidence of wound complications would not be reduced by perioperative HMB/Arg/Gln administration in patients who underwent open surgery. The efficacy of HMB/Arg/Gln for increasing serum GH levels needs to be validated in another large-scale randomized controlled trial. PMID: 30256751 [PubMed - in process] (Source: Wounds)
Source: Wounds - September 27, 2018 Category: General Medicine Tags: Wounds Source Type: research

Changes in the Biomechanical Properties of Human Skin in Hyperthermic and Hypothermic Ranges.
CONCLUSIONS: As per the results, the investigators believe these hyperthermic- and hypothermic-induced alterations in biomechanical skin properties are due to increased blood flow, in addition to a reversible increase in interstitial and intracellular fluid contents, thermal contraction, and expansion of collagen and elastic fibers, all of which are precursors to irreversible damage. PMID: 30256752 [PubMed - in process] (Source: Wounds)
Source: Wounds - September 27, 2018 Category: General Medicine Tags: Wounds Source Type: research

The Effects of Aloe vera on Wound Healing in Cell Proliferation, Migration, and Viability.
CONCLUSIONS: The results suggest A vera accelerates wound healing by promoting the proliferation and migration of fibroblasts and keratinocytes and by protecting keratinocytes from preservative-induced death. PMID: 30256753 [PubMed - in process] (Source: Wounds)
Source: Wounds - September 27, 2018 Category: General Medicine Tags: Wounds Source Type: research

Effect of Stem Cells on the Lower Limb.
Authors: Bolton L PMID: 30256754 [PubMed - in process] (Source: Wounds)
Source: Wounds - September 27, 2018 Category: General Medicine Tags: Wounds Source Type: research

A Rare Catch in a Nonhealing Wound.
CONCLUSIONS: This case illustrates the importance of considering atypical microbial infections in the workup for chronic nonhealing wounds. PMID: 30256755 [PubMed - in process] (Source: Wounds)
Source: Wounds - September 27, 2018 Category: General Medicine Tags: Wounds Source Type: research

Is There Adequate Perfusion for Healing? What Routine Noninvasive Vascular Studies are Missing?
CONCLUSIONS: Serial NIRI assessment in this case highlights its ability to detect factors that led to delayed would healing in the face of unreliable routine noninvasive vascular study results. PMID: 30256756 [PubMed - in process] (Source: Wounds)
Source: Wounds - September 27, 2018 Category: General Medicine Tags: Wounds Source Type: research

Retracted: Comparison of DNA Damage and Apoptosis Induced By Silver Nanoparticle-containing Dressing Materials During Wound Healing.
Authors: Choi YS, Gwak HC, Park JK, Lim JY, Yeo ED, Park E, Kim J, Lee YK Abstract The Editor and Publisher regretfully have to retract the following two publications due to faulty study design. PMID: 30212359 [PubMed - in process] (Source: Wounds)
Source: Wounds - September 14, 2018 Category: General Medicine Tags: Wounds Source Type: research

Retracted: Degree of the Hazards of Silver-Containing Dressings on MRSA-Infected Wounds in Sprague-Dawley and Streptozotocin-Induced Diabetic Rats.
Authors: Yeo ED, Yoon SA, Oh SR, Choi YS, Lee YK Abstract The Editor and Publisher regretfully have to retract the following two publications due to faulty study design. PMID: 30212360 [PubMed - in process] (Source: Wounds)
Source: Wounds - September 14, 2018 Category: General Medicine Tags: Wounds Source Type: research

Is PASH Syndrome a Biofilm Disease?: A Case Series and Review of the Literature.
CONCLUSIONS: As reported herein, based on biofilm's clinical presentation and resistance to proper wound healing, it could serve as the common denominator and may redirect clinicians' treatment pathways in the near future. PMID: 30212364 [PubMed - in process] (Source: Wounds)
Source: Wounds - September 14, 2018 Category: General Medicine Tags: Wounds Source Type: research

Efficacy of Dehydrated Human Amniotic Membrane Allograft for the Treatment of Severe Extravasation Injuries in Preterm Neonates.
Authors: Boyar V, Galiczewski C Abstract INTRODUCTION: A peripheral intravenous (PIV) catheter is placed in 60% to 70% of neonatal intensive care unit (NICU) infants. Extravasation injuries occur in 18% to 33%, with 70% in neonates
Source: Wounds - September 14, 2018 Category: General Medicine Tags: Wounds Source Type: research

The Role of Negative Pressure Wound Therapy in Managing Chinese Patients With Wound-derived Acute Severe Illness.
CONCLUSIONS: At PUMCH, the new collaborative salvage protocol with proactive use of NPWT with simultaneous life- support methods resulted in greater therapeutic effects than traditional salvage treatment could offer. PMID: 30212366 [PubMed - in process] (Source: Wounds)
Source: Wounds - September 14, 2018 Category: General Medicine Tags: Wounds Source Type: research

Surgical Site Infections Related to ESBL Pathogens Post Colon Surgery.
Authors: Oms L, Kalakouti E, Simillis C, Pellino G, Mughal N, Warren O, Mills S, Tan E, Kontovounisios C, Tekkis PP PMID: 30212367 [PubMed - in process] (Source: Wounds)
Source: Wounds - September 14, 2018 Category: General Medicine Tags: Wounds Source Type: research

Two Cases of Severe Erosive Pustular Dermatosis Mimicking Infection.
CONCLUSIONS: These cases represent the importance of considering topical steroid treatment and a diagnosis of EPDS after debridement for purulent scalp ulcers. PMID: 30212368 [PubMed - in process] (Source: Wounds)
Source: Wounds - September 14, 2018 Category: General Medicine Tags: Wounds Source Type: research

A Patient-centered Remote Therapy Monitoring Program Focusing on Increased Adherence to Wound Therapy: A Large Cohort Study.
Authors: Griffin L, Leyva Casillas LM Abstract OBJECTIVE: This retrospective study of 510 patients receiving negative pressure wound therapy (NPWT) in a home care setting examines the relationship between remote therapy monitoring (RTM) and patient adherence, as well as determines the impact of patient adherence on wound progression. MATERIALS AND METHODS: Adherence to treatment was continuously monitored via RTM, and patients with therapy usage
Source: Wounds - September 14, 2018 Category: General Medicine Tags: Wounds Source Type: research

Implantable Nanomedical Scaffold Facilitates Healing of Chronic Lower Extremity Wounds.
CONCLUSIONS: The implantable nanomedical scaffold proved to be an effective alternative to existing wound matrices capable of supporting the natural wound healing process and may provide significant benefits as part of the treatment algorithm for challenging chronic wounds. PMID: 30212370 [PubMed - in process] (Source: Wounds)
Source: Wounds - September 14, 2018 Category: General Medicine Tags: Wounds Source Type: research

Extract of Berula angustifolia (L.) Mertens Enhances Wound Healing in Streptozotocin-induced Diabetic Rats.
Authors: Sanaei N, Mohammadi R, Raisi A, Zarei L Abstract INTRODUCTION: Diabetes-impaired wound healing and other tissue abnormalities are considered to be a major concern. OBJECTIVE: The aim of this study is to assess the wound healing activity of the methanolic extracts of Berula angustifolia leaves. MATERIALS AND METHODS: Seven- week-old male Wistar rats with diabetes induced by streptozotocin injection were randomized into 5 groups of 6 rats based on allocated treatment. Wounds were created by an excision-based or incision-based wound model. For wound healing activity, the extracts were applied topicall...
Source: Wounds - September 14, 2018 Category: General Medicine Tags: Wounds Source Type: research

Pressure Injury Prevention Practices in the Intensive Care Unit: Real-world Data Captured by a Wearable Patient Sensor.
CONCLUSIONS: The investigators found dynamically measured turning frequency, turn magnitude, and tissue depressurization time to be suboptimal. This study highlights the need to reinforce best practices related to preventive turning and to consider staff and patient factors when developing individualized turn protocols. PMID: 30212372 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - September 14, 2018 Category: General Medicine Tags: Wounds Source Type: research

Soft Tissue Coverage of Complex Periprosthetic Defects in Patients With Total Knee Arthroplasty: Analysis of Factors That Influence Reconstructive and Functional Outcomes.
This study aims to identify those perioperative factors that influence reconstructive and functional outcomes in patients with periprosthetic TKA defects. MATERIALS AND METHODS: A 5-year retrospective review of outcomes following surgical management of TKA wounds was undertaken. Data pertaining to the timing of presentation, type and frequency of operative interventions, rates of implant/limb salvage, ambulatory status, visual analogue scores (VAS) for pain, and complications were collected. RESULTS: Thirty patients were identified during the study period with a mean follow-up of 20 months. Rates of limb salvage (6...
Source: Wounds - September 14, 2018 Category: General Medicine Tags: Wounds Source Type: research

Negative Pressure Wound Therapy of Open Abdomen and Definitive Closure Techniques After Decompressive Laparotomy: A Single-center Observational Prospective Study.
This study presents the evolution and complications related to the management of the open abdomen after decompressive laparotomy, using a standardized method based on negative pressure wound therapy (NPWT). MATERIALS AND METHODS: This observational prospective study conducted over a 9-month period included 19 patients who underwent decompressive laparotomies for ACS. The triggering conditions were peritonitis, infected and noninfected acute pancreatitis, ileus, and trauma. Temporary abdominal closure was performed using NPWT and the final closure by primary suture or dual mesh. Intra-abdominal pressure was permanently ...
Source: Wounds - September 14, 2018 Category: General Medicine Tags: Wounds Source Type: research

Insulated Offloading Provides Offloading Protection and Enhanced Skin Perfusion.
CONCLUSIONS: These findings suggest enhanced skin perfusion may be an additional advantage of insulated offloading boot or mitt use. PMID: 30212375 [PubMed - as supplied by publisher] (Source: Wounds)
Source: Wounds - September 14, 2018 Category: General Medicine Tags: Wounds Source Type: research

Study on Comparison of DNA Damage and Apoptosis is too Flawed to be Clinically Relevant.
Authors: Benskin L PMID: 30183663 [PubMed - in process] (Source: Wounds)
Source: Wounds - September 7, 2018 Category: General Medicine Tags: Wounds Source Type: research

Re: Degree of the Hazards of Silver-Containing Dressings on MRSA-Infected Wounds in Sprague-Dawley and Streptozotocin-Induced Diabetic Rat.
Authors: Benskin L PMID: 30183662 [PubMed] (Source: Wounds)
Source: Wounds - September 7, 2018 Category: General Medicine Tags: Wounds Source Type: research

DOMINATE Wounds.
Authors: Gale SS, Lurie F, Treadwell T, Vazquez J, Carman T, Partsch H, Alvarez O, Langemo D, Posthauer ME, Cheney M, Wilkin MM, Bursztynski M Abstract Chronic wounds are a significant health problem worldwide. Often they are initially managed with various focal treatments until a specialist becomes involved, sometimes weeks or months after treatment has begun. Even at the specialist level, practices and guidelines are inconsistent due to a lack of high-level evidence. A disease management system for chronic wounds that is simple, practical, and adoptable by a variety of wound care practitioners is needed. Such a s...
Source: Wounds - August 17, 2018 Category: General Medicine Tags: Wounds Source Type: research

Inpatient and Outpatient Wound Treatment Recommendations: Assessing Use of Negative Pressure Wound Therapy Systems or Oxidized Regenerated Cellulose (ORC)/ Collagen/Silver-ORC Dressings.
Authors: Applewhite A, Chowdhry SA, Desvigne M, Gabriel A, Hill R, Obst MA, Shepherd D, Speyrer M, Treadwell T, Waddell L Abstract The increase in wound prevalence means more patients with wounds are being transferred through care settings than ever before. Although the goals of therapy may be the same in both settings, wound care therapies and dressings differ in availability and appropriateness for each setting. Negative pressure wound therapy (NPWT) modalities and oxidized regenerated cellulose (ORC)/collagen (C)/silver-ORC dressings are available in both inpatient and outpatient care settings, but (to-date) lac...
Source: Wounds - August 15, 2018 Category: General Medicine Tags: Wounds Source Type: research

Considerations for Systemic and Topical Treatment of Morganella morganii Septicemia Arising from Maggot Infestation.
CONCLUSIONS: Myiasis can be invasive, leading to severe systemic infection. In these cases, a broad-spectrum antibiotic combined with systemic and topical antiparasitic therapy should be considered. PMID: 30059332 [PubMed - in process] (Source: Wounds)
Source: Wounds - August 1, 2018 Category: General Medicine Tags: Wounds Source Type: research

Microcystic Adnexal Carcinoma of the Nipple.
CONCLUSIONS: Between the confusing nomenclature, indolent course, and inadequacy of superficial biopsy to achieve an accurate diagnosis, MAC is a clinical entity that the plastic surgeon must be aware of in order to facilitate proper diagnosis and treatment. PMID: 30059333 [PubMed - in process] (Source: Wounds)
Source: Wounds - August 1, 2018 Category: General Medicine Tags: Wounds Source Type: research

Amniotic Membrane Adjuncts and Clinical Applications in Wound Healing: A Review of the Literature.
CONCLUSIONS: Overall, clinical trials have demonstrated that patients treated with amniotic membrane products have increased rates of wound healing compared with the standard of care. Additional trials are needed to examine more amnion/chorion membrane products. PMID: 30059334 [PubMed - in process] (Source: Wounds)
Source: Wounds - August 1, 2018 Category: General Medicine Tags: Wounds Source Type: research

Treatment of Nonreconstructable Critical Limb Ischemia With Ischemic Wounds Utilizing a Noninvasive Intermittent Pneumatic Compression Device Monitored With Fluorescence Angiography.
CONCLUSIONS: Larger randomized control trials of this modality of perfusion assessment and NPCD use are recommended. PMID: 30059338 [PubMed - in process] (Source: Wounds)
Source: Wounds - August 1, 2018 Category: General Medicine Tags: Wounds Source Type: research

Chlorhexidine Patient Bathing Prior to Arthroplasty.
Authors: Bolton L PMID: 30059339 [PubMed - in process] (Source: Wounds)
Source: Wounds - August 1, 2018 Category: General Medicine Tags: Wounds Source Type: research

Rare Presentation of Squamous Cell Carcinoma of the Foot in a Noncompliant HIV+ Patient.
CONCLUSIONS: This case shows the importance of patient compliance and timely treatment of SCC and surgical wounds in an immunosuppressed individual. PMID: 30059340 [PubMed - in process] (Source: Wounds)
Source: Wounds - August 1, 2018 Category: General Medicine Tags: Wounds Source Type: research

Fournier's Gangrene Does Not Spare Young Adults.
CONCLUSIONS: Fournier's gangrene is a surgical emergency, and the main cornerstones of treatment are patient resuscitation, broad-spectrum parenteral antibiotic therapy, and, most importantly, surgical debridement. Any delay in treatment can dramatically increase mortality. PMID: 30059341 [PubMed - in process] (Source: Wounds)
Source: Wounds - August 1, 2018 Category: General Medicine Tags: Wounds Source Type: research

Plasma Angiotensin-converting Enzyme Levels in Patients With Keloids and/or Hypertension.
CONCLUSIONS: Although the data showed no significant correlation between plasma ACE levels, keloids, and hypertension, additional studies may be pursued to determine the possible underlying role of ACE in keloid pathogenesis. PMID: 30059342 [PubMed - in process] (Source: Wounds)
Source: Wounds - August 1, 2018 Category: General Medicine Tags: Wounds Source Type: research