Genome diversity and evolutionary characteristics of clinical isolates of Bordetella pertussis circulating in Iran.
Conclusion: No changes in allelic profile of predominant clone in recent years was observed but antigenic divergence between recently circulating isolates and the vaccine strain has been progressed and significantly was higher than previous studies. The comparative genomic analysis of the ptxP3 and ptxP1 isolates indicate that changes in ptxP3 genome structure including 32 unique SNPs and three unique indels may have contributed to the expansion of the ptxP3 clone. We compared ptxP3 and ptxP1 isolates in pathogenicity-associated genes and found five of them were specific for the ptxP3 isolates. The polymorphisms in pathoge...
Source: Iranian Journal of Microbiology - April 24, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Prevalence and capsular type distribution of group B Streptococcus isolated from vagina of pregnant women in Nghe An province, Vietnam.
Conclusion: The prevalence of GBS in the Nghe An province of central Vietnam was similar to reports from other parts of the world. The predominat GBS serotypes (III, V, Ia and VI) were slightly different from those previously described from other regions around the world. The high frequency of serotype VI was a notable feature of the strains from pregnant women in Vietnam. PMID: 32322374 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - April 24, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Toxin A and B genes expression of Clostridium difficile in the sub-minimum inhibitory concentration of clindamycin, vancomycin and in combination with ceftazidime.
Conclusion: The results confirmed toxin gene transcription and toxin production are associated with the type of isolates and antibiotics, as well as the combined form of antibiotics. This could be the reason which can explain the occurrence of C. difficile infection among patients who were treated with the third generation of cephalosporins alone and in combination with another antibiotic in the form of combinational therapy. PMID: 32322375 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - April 24, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Detection and characterization of purified antigenic proteins from culture filtrate of Mycobacterium bovis strain AN5.
Conclusion: Immunoblotting analysis made it possible to detect and recognize novel antigens that are useful for bovine tuberculosis diagnosis improvement. This is significant since non-specific reactions were not observed when we utilized serum of cattle experimentally infected with M. bovis as a polyclonal antibody. PMID: 32322376 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - April 24, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Mutations in nalc gene of Mex AB-OprM efflux pump in carbapenem resistant Pseudomonas aeruginosa isolated from burn wounds in Yazd, Iran.
Conclusion: As the results showed, mutation in efflux pump was observed in carbapenem resistant isolate and this confirmed that the indiscriminate use of antibiotics for treatment or prophylaxis can increase mutation in efflux pump. PMID: 32322377 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - April 24, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

A novel method for the extraction of outer membrane vesicles (OMVs) from Bordetella pertussis Tohama strain.
Conclusion: The presented technique is a simple and effective way to obtain OMVs from Bordetella pertussis. So it can be utilized as an appropriate procedure in the development of an OMV-based vaccine against pertussis. PMID: 32322378 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - April 24, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Antibacterial potential of essential oils of Zataria multiflora and Mentha piperita, micro- and nano-formulated forms.
Conclusion: Regardless of the intrinsic antibacterial property of two examined EOs, by formulating to nanoemulsion, their efficiencies were improved. Nanoemulsion of ZMEO introduced as an inexpensive, potent and green antibacterial agent. PMID: 32322379 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - April 24, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

In vitro anti-biofilm activity of bacteriocin from a marine Bacillus sp. strain Sh10 against Proteus mirabilis.
Conclusion: The present findings indicated that bacteriocin from Bacillus sp. Sh10 has bactericidal properties against biofilm-forming isolates of P. mirabilis UCa4 and P. mirabilis UCe1 and has the ability to inhibit the formation of biofilm and disrupt established biofilm. PMID: 32322380 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - April 24, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Antimicrobial potential of lactic acid bacteria from domestic chickens (Gallus domesticus) from south Celebes, Indonesia, in different growth phases: in vitro experiments supported by computational docking.
Conclusion: B. subtilis strain PATA-5 is capable to produce natural antibiotic cyclic lipopeptides, namely surfactin. PMID: 32322381 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - April 24, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Co-detection of bocavirus and bacteria in a respiratory specimen from a pregnant woman using multiplex real time PCR; a pathogenic role, or a bystander?
Authors: Agin K, Rezaee I, Heydarifard Z, Jazayeri SM Abstract A pregnant woman presented by cough and dyspenia. Employing a respiratory multiplex real-time PCR, Human bocavirus (HBoV), Haemophilus influenza and Staphylococcus aureus were positive at cycle thresholds (CTs) of 21, 35 and 33.5, respectively. The patient was diagnosed for bacterial respiratory infection superimposed by bocavirus due to a relative high CT value. Patient's condition improved using bronchodilators and corticosteroid without any further antibiotic treatment. HBoV is not exclusively a bystander pathogen in some patients. PMID: 32322382...
Source: Iranian Journal of Microbiology - April 24, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Comparison of microbiome isolated from the conjunctiva, contact lens and lens storage case of symptomatic and asymptomatic contact lens users.
Authors: Raksha L, Shantala GB, Gangashettappa N, Ambica R, Sinha D Abstract Background and Objectives: Contact lenses (CLs) are increasingly being used for cosmetic or therapeutic purposes. Lack of compliance and poor hygiene towards lens care is strongly associated with microbial contamination and has been proved to result in eye infections. The present study was done to compare the microbial flora between symptomatic and asymptomatic contact lens users. The study also attempts to analyze the contact lens hygiene practices of CL users. Materials and Methods: Six samples each were collected from both the eyes,...
Source: Iranian Journal of Microbiology - March 11, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Prevalence of non-odontogenic infectious lesions of oral mucosa in a group of Iranian patients during 11 years: a cross sectional study.
Authors: Haghighat S, Rezazadeh F Abstract Background and Objectives: Oral mucosal infections are an important type of oral lesions. The aim of this study was to determine the epidemiology of oral mucosal infectious lesions in patients who referred to Oral Medicine Department of Shiraz Dental School, Iran during 11 years. Materials and Methods: In this cross sectional study, records of all patients who referred to Oral Medicine Department of Shiraz Dental School from September 2007 to January 2018 were assessed and those data sheets which their definitive diagnosis were a kind of oral mucosal infectious lesion ...
Source: Iranian Journal of Microbiology - March 11, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Antimicrobial susceptibility of Brucella spp. isolated from Iranian patients during 2016 to 2018.
Conclusion: Our data suggest that the efficacy of commonly used antibiotics for brucellosis treatment should be regularly monitored. In conclusion, appropriate precaution should be exercised in the context of antibiotic administration to prevent future antibiotic resistance. PMID: 32148665 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - March 11, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Determination of imipenem efflux-mediated resistance in Acinetobacter spp., using an efflux pump inhibitor.
Conclusion: The results obtained showed high levels of resistance to imipenem and contribution of efflux pumps in conferring resistance in both Acinetobacter species in this study. Moreover, imipenem efflux mediated resistance highlights the importance of this mechanism not only in A. baumannii but also in non-baumannii Acinetobacter Spp. which have been neglected in antibiotic resistance studies. PMID: 32148666 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - March 11, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Cloning and sequencing of the ompL37 gene present in Leptospira interrogans, a surface protein in pathogenic leptospires.
Conclusion: As the results showed, ompL37, present on the surface of such bacteria, showed a conserved sequence. ompL37, as a key role in cell adhesion and pathogenicity, can be used for designing diagnostic tests and vaccines. Furthermore, sequencing of various sites in ompL37 gene, including binding sites and immunogenic epitopes, can be valuable alternatives for future studies. PMID: 32148667 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - March 11, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Characterization of lactobacilli strains isolated from baby's feces for their potential immunobiotic application.
Conclusion: Two strains (Lactobacillus spp S14 and Lactobacillus spp S49) which showed the best immunobiotic characteristics, could be selected and evaluated more deeply in vivo model as well as in human clinical study to ensure their effectiveness in inflammatory diseases such as IBD. PMID: 32148668 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - March 11, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Probiotic Lactobacillus plantarum IS 10506 supplementation increase SCFA of women with functional constipation.
Conclusion: Probiotic Lactobacillus plantarum IS 10506 supplementation influenced all the SCFA parameter (acetate, propionate and butyrate). PMID: 32148669 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - March 11, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Physico-chemical and cytotoxic analysis of a novel large molecular weight bacteriocin produced by Lactobacillus casei TA0021.
Conclusion: The purified antimicrobial protein from L. casei TA0021 might be used for application in medicinal and food products. PMID: 32148670 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - March 11, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Improves in external and internal egg quality of Japanese quail (Coturnix coturnix japonica) by giving lactic acid bacteria as alternative antibiotic growth promoter.
Authors: Lokapirnasari WP, Al Arif A, Soeharsono S, Fathinah A, Najwan R, Wardhani HCP, Noorrahman NF, Huda K, Ulfah N, Yulianto AB Abstract Background and Objectives: An experiment was designed to determine the effect of using lactic acid bacteria as alternative antibiotic growth promoters on external and internal quality of egg's Coturnix coturnix japonica. Materials and Methods: Coturnix coturnix japonica (n=240, 14 weeks of age) were randomly distributed into six treatment groups. The treatments were P0 (free antibiotic feed), P1 (free antibiotic feed with 1 gram antibiotic growth promoters (AGP)/100kg feed...
Source: Iranian Journal of Microbiology - March 11, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

The effect of zinc supplementation on pro-inflammatory cytokines (TNF- α, IL-1 AND IL-6) in mice with Escherichia coli LPS-induced diarrhea.
Conclusion: Oral zinc supplementation had a significant positive effect on the levels of pro-inflammatory cytokines. Where there were higher levels of zinc, lower levels of pro-inflammatory cytokines TNF-α were present. PMID: 32148672 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - March 11, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Zinc solubilization characteristics of efficient siderophore-producing soil bacteria.
Conclusion: These findings demonstrated that the potential of P. japonica strains as plants growth promoting rhizobacteria (PGPR) in iron and zinc deficient soils. PMID: 32148673 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - March 11, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Comparison of cytokine profile of IFN- γ, IL-5 and IL-10 in cutaneous leishmaniasis using PBMC vs. whole blood.
Conclusion: There was no significant difference between IFN-γ, IL-10, IL-5 levels in whole blood and PBMC of volunteers with active lesion or history of CL. Whole-blood culture which is easier, cheaper and more convenient could be used instead of PBMC to evaluate the cytokine profile in field conditions. PMID: 32148674 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - March 11, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Serum protein electrophoresis pattern in patients living with HIV: frequency of possible abnormalities in Iranian patients.
Conclusion: Polyclonal gammopathy on SPEP is common among HIV-infected patients. Moreover, the SPEP patterns cannot be used as an indication of a patient's negative or positive response to treatment. PMID: 32148675 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - March 11, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Unraveling the importance of molecules of natural origin in antifungal drug development through targeting ergosterol biosynthesis pathway.
Authors: Jamzivar F, Shams-Ghahfarokhi M, Khoramizadeh M, Yousefi N, Gholami-Shabani M, Razzaghi-Abyaneh M Abstract Over the past decades, the incidence of life-threatening fungal infections has increased dramatically in particular among patients with hampered immune function. Fungal infections cause around 1.5 million deaths annually, superior to malaria and tuberculosis. With respect to high toxicity, narrow spectrum of activity and drug resistance to current antifungals, there is an urgent need to discover novel leads from molecules of natural origin especially those derived from plants and microorganisms for an...
Source: Iranian Journal of Microbiology - March 11, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Reducing urinary oxalate by simultaneous using Sankol herbal drop with oxalate-degrading bacteria.
Conclusion: This is the first study on the simultaneous use of Sankol herbal drop and oxalate-degrading probiotic bacteria that showed a significant reduction in urinary oxalate. PMID: 32148677 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - March 11, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Surveillance of antibiotic resistance among uropathogens in Aljouf region northern Saudi Arabia.
Conclusion: The observed widespread multidrug resistance clearly warrant implementing stricter control measures, local guidelines of antimicrobials usage, and continuous epidemiological surveys at hospitals and communities. PMID: 32148678 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - March 11, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

The relationship between phylogenetic groups and antibiotic susceptibility patterns of Escherichia coli strains isolated from feces and urine of patients with acute or recurrent urinary tract infection.
Conclusion: Although phylo-groups B2 and D of E. coli bacteria are more responsible for UTI, group D isolates seem to be more resistant and probably more virulent, even than the ones from group B2. PMID: 32148679 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - March 11, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Bacterial vaginosis and antibacterial susceptibility pattern of asymptomatic urinary tract infection in pregnant women at a tertiary care hospital, Visakhaptn, India.
Conclusion: Bacterial vaginosis was more common than asymptomatic bacteriuria in pregnant women. It is recommended that antenatal health care facilities should incorporate screening of vaginitis among pregnant women to prevent the complications of pregnancy. And those women with Bacterial vaginosis should be screened for UTI. Proper use of antibiotics should be encouraged, abuse of antibiotics should be in check. PMID: 32148680 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - March 11, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Molecular characterization of quinolone resistant Shigella spp. isolates from patients in Ardabil, Iran.
Conclusion: This study provided information on the prevalence and antimicrobial susceptibility patterns of Shigella isolates in Ardabil province, Iran. Also this study showed a high-level of resistance to commonly used antibiotics among Shigella isolates. PMID: 32148681 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - March 11, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Antibiotic resistance pattern of Acinetobacter baumannii from burns patients: increase in prevalence of bla OXA-24-like and bla OXA-58-like genes.
Conclusion: Resistance to carbapenems as the last resort for treatment of A. baumannii infections is growing. This study, for the first time in Iran, has observed the increased frequency of bla OXA-24-like and bla OXA-58-like genes and found an association between ISAba-1 and bla OXA-58-like gene, which signifies the possible risk of increased diversity in OXA beta-lactamases and growth in carbapenem resistance. PMID: 32148682 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - March 11, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

The potency of luliconazole against clinical and environmental Aspergillus nigri complex.
Conclusion: Luliconazole versus amphotericin B, voriconazole, posaconazole and caspofungin is a potent antifungal for Aspergillus Nigri complex. The in vitro extremely antifungal efficacy against black Aspergillus strains of luliconazole, is different from those of other used antifungals. PMID: 32148683 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - March 11, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Antifungal susceptibility of non-albicans Candida spp. isolated from raw milk and human blood in Alborz and Tehran provinces.
Conclusion: Evaluation of non-albicans Candida species in raw milk and antifungal susceptibility patterns of these isolates-compare with non-albicansisolates from human blood, may help physicians to choose an appropriate medication for diseases needing long-term treatment, especially for diseases caused by local strains. PMID: 32148684 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - March 11, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Evaluation of hygienic conditions of food contact surfaces in a hospital kitchen in Morocco.
Conclusion: The actual results indicate that the high levels of bacterial counts on kitchen surfaces, presents an evident need to improve the hygienic process and adopt an HACCP system in this facility. PMID: 32148685 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - March 11, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Prevalence of hepatitis E virus in thalassemia patients with hepatitis C in Tehran, Iran.
Conclusion: Seroprevalence of HEV in our study group was 1.67% which is less than HEV seroprevalence rate in Iranian general population. Therefore, it can be conclude that transmission of HEV infection via blood transfusion seems to be uncommon in Iran and the fecal-oral route can be the predominant mode of transmission in Iran; however, more studies are required to confirm this issue. PMID: 32148686 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - March 11, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

The effect of a single-strain probiotic administration in the treatment of thermal burns patients.
Conclusion: The Bifidobacterium infantis 35624 single-strain probiotic is generally superior to Lactobacillus reuteri protectis in altering intestinal immunity; however, this finding was not statistically significant. A multi-strain probiotic supplement is recommended for burns patients. PMID: 32148687 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - March 11, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Primary tonsillar tuberculosis: a forgotten clinical identity.
Authors: Motahari SJ, Afshar P, Ghasemi M, Larijani LV, Sheidaei S Abstract Primary tonsillar tuberculosis is an uncommon entity and a diagnostic challenge. Misdiagnosis can be prevented with early professional para-clinical finding. The true diagnosis is often delayed and infection management depends on recognizing disease patterns and early laboratory documentation. This rare clinical caseation granuloma with positive clinical symptoms, negative results of radiology/laboratory and alone based on histopathological finding without any Mycobacterium particle indicates the role of an accurate laboratory/pathology fin...
Source: Iranian Journal of Microbiology - March 11, 2020 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Cutaneous candidiasis in Tehran-Iran: from epidemiology to multilocus sequence types, virulence factors and antifungal susceptibility of etiologic Candida species.
Conclusion: Our results demonstrated clinical epidemiology of various Candida species from cutaneous candidiasis distributed in new molecular types with increasing importance of drug resistant of non-albicans Candida species. Our results showed that drug susceptibility and genetic variability of Candida species may be attributed to their clinical features and source of isolation. PMID: 31719957 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - November 15, 2019 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Detection of bla CTX-M15 and bla OXA-48 genes in Gram-negative isolates from neonatal sepsis in central of Iran.
Conclusion: The high antibiotic resistance among the isolates reveals the importance of monitoring antibiotic consumption and improving control standards in the health care system, especially in neonatal wards. PMID: 31719958 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - November 15, 2019 Category: Microbiology Tags: Iran J Microbiol Source Type: research

The role of the bla KPC gene in antimicrobial resistance of Klebsiella pneumoniae.
Conclusion: In this study nearly half the isolates showed carbapenemase activity as shown by MHT results, but only few of them were carrying bla KPC. Thus bla KPC gene is not the main cause of resistance spread to carbapenems in Isfahan, Iran. PMID: 31719959 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - November 15, 2019 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Differences in systemic humoral immune response among Balb/c mice administered with probiotic, LPS Escherichia coli, and probiotic-LPS E. coli.
Conclusion: Probiotic-LPS derived from E. coli treatment induced a higher humoral immune response (highest IgE, IgA, IgG and IgM levels) compared to treatment with probiotic only. PMID: 31719960 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - November 15, 2019 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Effects of a multispecies synbiotic on intestinal mucosa immune responses.
Conclusion: The multispecies synbiotic had immunoregulatory effects on IgA and CD4 expression in LPS-exposed mice. PMID: 31719961 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - November 15, 2019 Category: Microbiology Tags: Iran J Microbiol Source Type: research

The effect of Bacillus coagulans on cytotoxicity and apoptosis induced by Salmonella Typhimurium in HT-29 cell culture.
Conclusion: B. coagulans can reduce the adhesion, cytotoxicity and induction of apoptosis caused by S. Typhimurium in HT-29 cells in vitro. PMID: 31719962 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - November 15, 2019 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Antibacterial activity of self-adhesive resin cements against Streptococcus mutans at different time intervals.
Authors: Ajami AA, Rikhtegaran S, Bahari M, Hamadanchi S Abstract Background and Objectives: Self-adhesive resin cements release fluoride and have cytotoxic and preventive monomers against the bacteria in their composition. They have acidic property before their complete setting too. The antibacterial activity of three different self-adhesive resin cements against Streptococcus mutans at different time intervals was investigated in this study. Materials and Methods: The modified direct contact test was used to evaluate the antibacterial effect of Max-Cem, G-Cem and Bis-Cem on S. mutans after aging the samples i...
Source: Iranian Journal of Microbiology - November 15, 2019 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Purification and study of anti-cancer effects of Serratia marcescens serralysin.
Conclusion: Our results showed that native serralysin has anticancer potential and may be a candidate for further pharmaceutical research and development. Further in vivo and in vitro mechanistic studies are suggested to confirm the biological activities. PMID: 31719964 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - November 15, 2019 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Fibrinolysin production by Alcaligenes faecalis strain 26 isolated from environment.
Conclusion: Based on the obtained results it can be suggested that Alcaligenes faecalis strain 26 has appropriate efficiency for fibrinolysin production that can be used in food industry and medicine. PMID: 31719965 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - November 15, 2019 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Rheumatoid arthritis mediator CD18 expression by Staphylococcus aureus superantigen C in rats.
Conclusion: The results indicated that the presence of Staphylococcal of superantigen C in the body of rats has enhanced the expression of the CD18 inflammatory marker more than 3 times. This valuable finding is an introduction to further research and could provide new methods to prevent and control inflammatory diseases, including rheumatoid arthritis. PMID: 31719966 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - November 15, 2019 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Maxillary sinus aspergillosis: a case report of the timely failure to treatment.
This study reported a case of maxillary aspergillosis with a complete headache and eye pain after tooth extraction with a large abscess in the relative jaw. Tenderness in the right temporal, lower jaw numbness and right eye proptosis was found. Histopathological examination was the suggestion of maxillary sinusitis with a fungal ball of aspergillus. PMID: 31719967 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - November 15, 2019 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Investigation of iron uptake and virulence gene factors (fur, tonB, exbD, exbB, hgbA, hgbB1, hgbB2 and tbpA) among isolates of Pasteurella multocida from Iran.
Conclusion: More studies need to be conducted on the frequency of all other virulence factors among these isolates, which can provide basic information for improvement or substitution of current vaccinal strains. Overall, as the new designed sets of primers showed more potential in detecting the corresponded genes, researchers can consider them in further studies. PMID: 31523401 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - September 18, 2019 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Concurrent detection of cagA, vacA, sodB and hsp60 virulence genes and their relationship with clinical outcomes of disease in Helicobacter pylori isolated strains of southwest of Iran.
Conclusion: The obtained results are similar to some studies conducted in different parts of the world and is different in other cases. This discrepancy is due to the difference in the type of gastric disorders, sample size and methodology. PMID: 31523402 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - September 18, 2019 Category: Microbiology Tags: Iran J Microbiol Source Type: research

Comparison of Helicobacter pylori stool antigen, salivary IgG, serum IgG, and serum IgM as diagnostic markers of H. pylori infection in children.
Conclusion: The results of this study showed that HpSA, salivary IgG, and serum IgG and IgM were not sufficient to replace endoscopic-biopsy as the gold standard for the diagnosis of H. pylori infection. PMID: 31523403 [PubMed] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - September 18, 2019 Category: Microbiology Tags: Iran J Microbiol Source Type: research