Sequelae After Involution of Superficial Infantile Hemangioma: Early Intervention with 595-nm Pulsed Laser Combined with 755-nm Long-Pulsed Alexandrite Laser versus Wait-and-See.
Authors: Jiang JC, Xu Q, Fang S, Gao Y, Jin WW Abstract Background and Objective: Infantile haemangioma (IH) is the most common benign tumor in children. At present, pulsed dye laser (PDL) has made great progress in the treatment of superficial IH, showing good safety and effectiveness. But some doctors think that superficial IH should choose to wait-and-see. However, studies have reported that most of the IH after resolution still has residual disease, and thickness seems to be an important factor. Therefore, the purpose of this study is to investigate the relationship between Sequelae and thickness after superfic...
Source: Clinical, Cosmetic and Investigational Dermatology - January 21, 2021 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

The Science of Absorbable Poly(L-Lactide-Co- ε-Caprolactone) Threads for Soft Tissue Repositioning of the Face: An Evidence-Based Evaluation of Their Physical Properties and Clinical Application.
The Science of Absorbable Poly(L-Lactide-Co-ε-Caprolactone) Threads for Soft Tissue Repositioning of the Face: An Evidence-Based Evaluation of Their Physical Properties and Clinical Application. Clin Cosmet Investig Dermatol. 2021;14:45-54 Authors: Wong V Abstract The use of bioabsorbable threads has become a common minimally invasive technique for the nonsurgical lifting of sagged facial tissues. It entails the passage of barbed threads that form a support structure under the skin of the face and neck to mechanically reposition sagging tissue. Poly(L-lactide-co-ε-caprolactone) has long...
Source: Clinical, Cosmetic and Investigational Dermatology - January 21, 2021 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Allergy - Patients with Atopic Dermatitis Express Themselves Through a Questionnaire.
Authors: Shourick J, Taïeb C, Seite S Abstract Introduction: Allergies are becoming more prevalent across the globe and can be linked to several skin diseases, particularly atopic dermatitis (AD). Disruption of the immune system in the skin can lead to inflammatory diseases such as atopic and contact dermatitis, skin infections, and allergies. This is especially evident in processes such as "atopic march", where in childhood, the development of atopic dermatitis can later lead to food allergies, allergic rhinitis and asthma. Objective: The aim of this international online survey is to study the l...
Source: Clinical, Cosmetic and Investigational Dermatology - January 17, 2021 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Clinical Approach to Linear Hyperpigmentation: A Review Article.
Authors: Alkhowailed MS, Otayf M, Albasseet A, Almousa A, Alajlan Z, Altalhab S Abstract Linear hyperpigmentation is an unusual anatomical configuration in clinical dermatology. Owing to its rarity, consensus on the most effective method of classification is lacking. While linear hyperpigmentation generally follows Blaschko's lines, this is not universal. Clinical findings such as adherence to Blaschko's lines, associated morphological findings (including other cutaneous lesions), and systemic manifestations can be used to further characterize and diagnose variants of the disorder. Early detection of any underlying...
Source: Clinical, Cosmetic and Investigational Dermatology - January 17, 2021 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Inflammation and Vascular Injury as the Basis of COVID-19 Skin Changes: Preliminary Analysis of 23 Patients from the Literature.
Authors: Zheng Y, Gong Z, Chen J, Lin Y, Liu Y Abstract Background: COVID-19 can affect various organ systems including the skin. Cutaneous manifestations of COVID-19 in infected patients are poorly characterized. Objective: To summarize retrospectively the skin features of COVID-19 infection and to analyze the skin rash incidence rate, clinical onset time, cutaneous manifestations, pathological characteristics and relationship with the novel coronavirus pneumonia severity. Methods: The literature up to Sep 20, 2020, were searched and analyzed. Information on clinical features including skin manifestations,...
Source: Clinical, Cosmetic and Investigational Dermatology - January 15, 2021 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Personal-Care Cosmetic Practices in Pakistan: Current Perspectives and Management.
Authors: Khan NH, Ullah F, Khan TA, Zafar U, Farhan Ali Khan M, Mustaqeem M, Shah SS, Wu DD, Ji XY Abstract To look superior and acceptable in society, people from all over the world use various types of cosmetic products to enhance or alter their facial appearance and body texture. In recent times, an exponential surge in cosmetic use has been observed in Pakistan, and hence spending money on personal-care products is high. However, there are many reported facts about high loads of lead, mercury, copper, and others hazardous and cancerous elements in local Pakistani cosmetic brands. Consumers of these brands ...
Source: Clinical, Cosmetic and Investigational Dermatology - January 15, 2021 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Glucocorticoid-Induced Skin Atrophy: The Old and the New.
Authors: Niculet E, Bobeica C, Tatu AL Abstract Glucocorticoids are major therapeutic agents highly used in the medical field. Topical glucocorticoids have biologic activities which make them useful in dermatology - anti-inflammatory, vasoconstrictive, immune suppressive and antiproliferative, in treating inflammatory skin disorders (allergic contact eczema, atopic hand eczema, nummular eczema, psoriasis vulgaris or toxic-irritative eczema). Unfortunately, the beneficial effects of topical glucocorticoids are shadowed by their potential for adverse effects - muscle or skin atrophy, striae distensae, rubeosis or acn...
Source: Clinical, Cosmetic and Investigational Dermatology - January 8, 2021 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Efficacy of a Topical Product Containing Purified Omental Lipids and Three Anti-Itching Compounds in the Treatment of Chronic Pruritus/Prurigo Nodularis in Elderly Subjects: A Prospective, Assessor-Blinded, 4-Week Trial with Transepidermal Water Loss and Optical Coherence Tomography Assessments.
Conclusion: This purified omental lipid with three anti-itching components cream reduces significantly itch intensity in subjects with chronic pruritus/prurigo nodularis, improving the skin barrier function and skin structure. Trial Number: ISRCTN869561669. PMID: 33408496 [PubMed] (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - January 8, 2021 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Can Sodium Thiosulfate Act as a Reversal Agent for Calcium Hydroxylapatite Filler? Results of a Preclinical Study.
Discussion: Results suggest no indication of CaHA microspheres degradation with STS and that the STS mechanism of action on CaHA is consistent with a dispersion effect. Observed necrosis is a further obstacle in the use of STS. PMID: 33408497 [PubMed] (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - January 8, 2021 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Cost Effectiveness of Emollients in the Prevention of Relapses in Atopic Dermatitis.
Discussion: According to the analysis, treatment with preventive emollient was a cost-effective option compared with no treatment in adult AD patients. In this comparative study, emollient A is the most efficient strategy from a willingness to pay £200 with a probability of 49%. PMID: 33376376 [PubMed] (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - January 1, 2021 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Microneedling for the Treatment of Scars: An Update for Clinicians.
Conclusion: MN is a well-tolerated, minimally invasive procedure that can be used for the treatment of scars with a high level of patient satisfaction. Further clinical studies are needed to develop standardized treatment protocols. PMID: 33376377 [PubMed] (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - January 1, 2021 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Assessment of the Effect of Metabolic Syndrome on the Autophagy Marker LC3 in Psoriasis Vulgaris Patients: A Cross-Sectional Study.
Conclusion: A potential link between psoriasis vulgaris and autophagy as assessed by LC3 could be present. LC3 was down-regulated in psoriasis lesions than in normal skin. However, its expression did not change with PASI or MetS. An autophagy enhancer might be used as a possible therapeutic target in psoriasis vulgaris patients. PMID: 33376378 [PubMed] (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - January 1, 2021 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Giant Lipoma in the Fronto-Temporo-Parietal Region in an Adult Man: Case Report and Literature Review.
Authors: Szewc M, Gawlik P, Żebrowski R, Sitarz R Abstract Lipoma belongs to a group of benign mesenchymal tumors. It is in the form of soft masses of adipose tissue encapsulated by a thin layer of fibrous tissue and usually localized subcutaneously. The tumor most often appears in the upper part of the body. Lipomas tend to grow slowly and are small (less than 5cm) lesions. Larger tumors are rare. In this article, we present the case of a patient with a giant head lipoma in the fronto-temporo-parietal region. Both tumor size and location are unique and no such case has been described in the literature so far. ...
Source: Clinical, Cosmetic and Investigational Dermatology - January 1, 2021 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

The Skin Interactome: A Holistic "Genome-Microbiome-Exposome" Approach to Understand and Modulate Skin Health and Aging.
In conclusion, we have, through our digital holistic approach, defined the skin interactome concept, as an advanced tool to better understand the molecular genesis of skin aging and further develop a strategy to balance the influence of the exposome and microbiome to protect, prevent, and delay the appearance of skin aging signs and preserve good skin health condition. In addition, this model will aid in identifying and optimizing skin treatment options based on external triggers, as well as helping to design optimal treatments modulating the intrinsic pathways. PMID: 33380819 [PubMed] (Source: Clinical, Cosmetic and I...
Source: Clinical, Cosmetic and Investigational Dermatology - January 1, 2021 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Human Adipose-Derived Mesenchymal Stem Cells-Derived Exosomal microRNA-19b Promotes the Healing of Skin Wounds Through Modulation of the CCL1/TGF- β Signaling Axis.
Conclusion: Our study indicates that exosomal miR-19b derived from ADMSCs regulates the TGF-β pathway by targeting CCL1, thereby promoting the healing of skin wounds. PMID: 33364805 [PubMed] (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - December 29, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Development and Validation of an Immune-Related Gene Pair Signature in Skin Cutaneous Melanoma.
Conclusion: In summary, we developed a robust 13-IRGP prognostic signature in SKCM, which can identify and provide new insights into immunological biomarkers. PMID: 33364806 [PubMed] (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - December 29, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Self-Reported Skin Sensation by People Who Have Experienced Containment During COVID-19 Pandemic.
Authors: Kluger N, Le Floc'h C, Niore M, Delvigne V, Le Dantec G, Taieb C PMID: 33328752 [PubMed] (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - December 19, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Therapeutic Potential of Cannabidiol (CBD) for Skin Health and Disorders.
This article provides an update on the advances in CBD research to date and the potential areas of future exploration. PMID: 33335413 [PubMed] (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - December 19, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Novel Management of Rhinophyma by Patterned Ablative 2940nm Erbium:YAG Laser.
Conclusion: In conclusion, the use of patterned ablative Er:YAG laser with a PS01 handpiece and parameters used in this study comprise an effective tool for treatment of mild to moderate rhinophyma with rapid postoperative recovery compared with conventional surgical procedures and other ablative lasers. PMID: 33335414 [PubMed] (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - December 19, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

The Interaction of Age and Anatomical Region Influenced Skin Biophysical Characteristics of Chinese Women.
Conclusion: This study indicates that the skin biophysical characteristics of Chinese women were significantly affected by age and body regions. PMID: 33324083 [PubMed] (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - December 18, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Optimal Management of Frontal Fibrosing Alopecia: A Practical Guide.
This article is a review of the literature on treatment modalities for FFA and the objective is to offer a practical guide for clinicians on the evidence-based management options currently available in the literature. PMID: 33293846 [PubMed] (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - December 11, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Honey Combination Therapies for Skin and Wound Infections: A Systematic Review of the Literature.
Authors: McLoone P, Tabys D, Fyfe L Abstract Topical application of medical grade honey is recommended for the clinical management of wound infections. The suitability of honey as a wound healing agent is largely due to its antibacterial activity, immune modulatory properties, and biocompatibility. Despite the usefulness of honey in wound healing, chronic wound infections continue to be a global problem requiring new and improved therapeutic interventions. Several recent studies have investigated the effects of combining honey with other therapies or agents with the aim of finding more efficacious treatments. In th...
Source: Clinical, Cosmetic and Investigational Dermatology - December 4, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

TGF- β1 Gene Polymorphism and Its Correlation with Serum Level of TGF-β1 in Psoriasis Vulgaris Among Iraqi People.
Conclusion: Iraqi population showed a significant association between TGF-β1 gene polymorphism at codon 10 and 25 were with psoriasis susceptibility, and a significantly lower mean serum TGF-β1 level was detected in psoriatic patients. PMID: 33262631 [PubMed] (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - December 4, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Clinical and Onychoscopic Features of Benign and Malignant Conditions in Longitudinal Melanonychia in the Thai Population: A Comparative Analysis.
Conclusion: Onychoscopy provides useful information to aid in the differential diagnosis of longitudinal melanonychia. From our study, onychoscopy can be utilized to assist in making a decision whether to perform a biopsy in patients with longitudinal melanonychia suspicious of malignant melanocytic conditions. PMID: 33244251 [PubMed] (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 29, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Nationwide Survey and Identification of Potential Stress Factor in Sensitive Skin of Chinese Women.
Conclusion: Having a combination or oily skin type, living in the municipalities, being under heavy stress, and applying several cosmetic products will increase skin stress and contribute to the occurrence of sensitive skin. PMID: 33244252 [PubMed] (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 29, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Effect of TNF- α -308G/A (rs1800629) Promoter Polymorphism on the Serum Level of TNF-α Among Iraqi Patients with Generalized Vitiligo.
Conclusion: TNF-α in the serum is a risk factor for generalized vitiligo among Iraqi patients. Patients with active vitiligo have a higher serum TNF-α level. No difference was found between serum level of TNF-α with TNF-α polymorphism at position -308 (TNF -308). This involves substituting G allele for the A allele. PMID: 33223842 [PubMed] (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 25, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Lentigo Maligna: Clinical Presentation and Appropriate Management.
Authors: Iznardo H, Garcia-Melendo C, Yélamos O Abstract Lentigo maligna (LM) is a type of melanoma in situ that has distinctive characteristics regarding epidemiology, risk factors and clinical features. In addition, LM has a potential to progress to an invasive tumor with potentially aggressive behavior: lentigo maligna melanoma (LMM). Overall, LM has a very good prognosis, whereas LMM has the same prognosis as other invasive melanomas with similar Breslow thickness. LM/LMM represents a challenging entity not only regarding the diagnosis but also regarding the management. Diagnostic criteria are not well e...
Source: Clinical, Cosmetic and Investigational Dermatology - November 25, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Contraception, Sexuality and Pregnancy in Women with Psoriasis: Real-Life Experience of 235 Women.
Conclusion: Our study shows that the management of women of childbearing age with psoriasis must be improved with respect to sexuality, contraception and pregnancy planning. PMID: 33204135 [PubMed] (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 21, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

A Retrospective Comparative Study of Two Concentrations of Intralesional Triamcinolone Acetonide in the Treatment of Patchy Alopecia Areata on the Scalp.
Conclusion: Intralesional injection of triamcinolone acetonide 5 mg/mL is equally effective and safe compared to 10 mg/mL in the treatment of patchy alopecia areata. PMID: 33173320 [PubMed] (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 14, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Clinical Trial of Low Irritative Skin Care Cosmetics in Japanese Subjects with Dry Skin.
Conclusion: Four weeks of MediQOL use resulted in the alleviation of skin dryness, redness, and itchiness and balanced the water/oil content of the skin. MediQOL is expected to be effective in improving the condition of various skin types, including oily, mixed, and sensitive skin as well as dry skin. PMID: 33173321 [PubMed] (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 14, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Erratum: Vitamin D Levels in Patients with and without Acne and Its Relation to Acne Severity: A Case-Control Study [Corrigendum].
Authors: Abstract [This corrects the article DOI: 10.2147/CCID.S271500.]. PMID: 33173322 [PubMed] (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 14, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

A Novel OnabotulinumtoxinA Treatment Technique to Obtain Predictable Outcomes in Eyebrow Position and Shape.
Conclusion: The proposed injection technique, when diligently followed, ensures that the final eyebrow position is pleasing and symmetrical with a negligible risk of any untoward effects. PMID: 33149650 [PubMed] (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 6, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Feasibility Study for the Long-Term Management of Refractory Hyperkeratotic Eczema with Calcipotriol and Betamethasone Dipropionate (Daivobet ®), Viaminate and Concomitant Conventional Therapies: A Retrospective Study.
Feasibility Study for the Long-Term Management of Refractory Hyperkeratotic Eczema with Calcipotriol and Betamethasone Dipropionate (Daivobet®), Viaminate and Concomitant Conventional Therapies: A Retrospective Study. Clin Cosmet Investig Dermatol. 2020;13:789-794 Authors: Nabatanzi A, Mafuru M, Male M, Tian C, Zhang L, Wu T, Wu S, Huang C Abstract Background: The available treatments for refractory hyperkeratotic eczema are inadequate with frustrating results. We, therefore, incorporated Calcipotriol and Betamethasone Dipropionate (Daivobet®), and Viaminate into the mainstay treatment to impro...
Source: Clinical, Cosmetic and Investigational Dermatology - November 6, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Differences of Microbiomes Found in Non-Inflammatory and Inflammatory Lesions of Acne Vulgaris.
Conclusion: Differences in bacterial isolates were observed both in non-inflammatory and inflammatory lesions of AV. PMID: 33122933 [PubMed] (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 1, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

A Split-Face Study Assessing the Clinical Benefit, Tolerability and Subject Satisfaction of a Dermocosmetic in Subjects with Rosacea Associated with Erythema and Sensitive Skin.
This study assessed the efficacy and tolerability of M89 in patients with rosacea associated with erythema and sensitive skin. Methods: Intra-individual study in a split-face design comparing after 30 days M89 twice daily and usual skin care in 20 adult subjects with rosacea and sensitive skin. M89 contains 89% Vichy volcanic mineralizing water (VVMW) and 0.4% hyaluronic acid. It is hypoallergenic and contains no perfume and this convenes in rosacea. Contained minerals reinforce the natural defences of the skin in restoring the natural skin barrier, stimulating antioxidant activity and reducing inflammation, commonly o...
Source: Clinical, Cosmetic and Investigational Dermatology - October 30, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Vitamin D Levels in Patients with and without Acne and Its Relation to Acne Severity: A Case-Control Study.
Conclusion: This study has shown clearly that vitamin D deficiency is more frequent in patients with acne with P-value = 0.003. However, no significant association between the serum level of 25-hydroxyvitamin D [25 (OH) D] and the severity of acne vulgaris. Further clinical trials on a larger scale are needed to address the importance of vitamin D in acne vulgaris. Specifically, determining whether treatment of acne with both topical vitamin D analogs and vitamin D supplementation is of significant effect. PMID: 33116739 [PubMed] (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - October 30, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Complications Following Self-Administration of Hyaluronic Acid Fillers: Literature Review.
Authors: Rauso R, Nicoletti GF, Zerbinati N, Lo Giudice G, Fragola R, Tartaro G Abstract The purpose of the present study is to review published literature regarding complications following self-administration of hyaluronic acid (HA) filler. The following keywords were searched in Pubmed and Cochrane database: filler AND self injection, hyaluronic acid AND self injection; filler AND self administration; hyaluronic acid AND self administration. Two authors performed title and abstract eligibility assessment independently. Gray literature and all articles cited in the included papers were also screened and their refe...
Source: Clinical, Cosmetic and Investigational Dermatology - October 30, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Clinical Study to Evaluate the Efficacy and Safety of a Hair Serum Product in Healthy Adult Male and Female Volunteers with Hair Fall.
Discussion: After 90 days of test product application, there was a significant improvement in hair growth rate (
Source: Clinical, Cosmetic and Investigational Dermatology - October 20, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Effect of Hyaluronic Acid and Poly-L-Lactic Acid Dermal Fillers on Collagen Synthesis: An in vitro and in vivo Study.
Authors: Cabral LRB, Teixeira LN, Gimenez RP, Demasi APD, de Brito Junior RB, de Araújo VC, Martinez EF Abstract Purpose: Skin ageing is marked by structural and functional changes in epidermis and dermis, which result clinically in wrinkles, loss of elasticity, and rough-textured appearance. In this context, different dermal fillers have been used to overcome these negative effects associated with skin ageing, such as hyaluronic acid (HA) and poly-L-lactic acid (PLLA). Despite their low immunogenicity, these materials can cause an inflammatory reaction after application. Materials and Methods: Consideri...
Source: Clinical, Cosmetic and Investigational Dermatology - October 20, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Severity of Acne Vulgaris: Comparison of Two Assessment Methods.
Conclusion: The two methods for acne severity assessment are reliable, and they are correlated. Quality of life concerning acne is not correlated with the severity of the disease. PMID: 33061511 [PubMed] (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - October 20, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Sun Awareness and Sun Protection Practices.
Conclusion: Most of the respondents are aware about sun protection. However, the sun protection level of the residents is still inadequate. An efficient strategy of increasing the awareness of the effective use of sun protection systems must be established based on the significant factors to prevent skin cancer. PMID: 33061512 [PubMed] (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - October 20, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Multiple Skin Neoplasms at One Site (MUSK IN A NEST): A Comprehensive Review of Basal Cell Carcinoma and Benign or Malignant "Collision" Tumors at the Same Cutaneous Location.
Multiple Skin Neoplasms at One Site (MUSK IN A NEST): A Comprehensive Review of Basal Cell Carcinoma and Benign or Malignant "Collision" Tumors at the Same Cutaneous Location. Clin Cosmet Investig Dermatol. 2020;13:731-741 Authors: Cohen PR, Calame A Abstract Multiple skin neoplasms at one site (MUSK IN A NEST), initially referred to as a collision tumor, describes the occurrence of two or more benign or malignant neoplasms that are adjacent or intermingled at the same cutaneous site. A mononeoplastic cutaneous tumor refers to a single tumor at any cutaneous site. Two, three, four, five, and ...
Source: Clinical, Cosmetic and Investigational Dermatology - October 20, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Updates on Genital Dermatophytosis.
Authors: Thakur R, Kalsi AS Abstract Dermatophytes are a group of keratinophilic fungi, which normally cause superficial infection of skin, hair and nails. Based on ecology, they are classified into three groups: anthropophilic, zoophilic and geophilic. Superficial dermatophytic infection of the genital region is called genital dermatophytosis, tinea genitalis or pubo-genital dermatophytosis. In this review, we would like to discuss briefly, the various clinical presentations of genital dermatophytosis, current changes in the taxonomy and nomenclature, introduction of new diagnostic techniques and briefly describe ...
Source: Clinical, Cosmetic and Investigational Dermatology - October 20, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Honey and Chamomile Activate Keratinocyte Antioxidative Responses via the KEAP1/NRF2 System.
Conclusion: Our results may offer an opportunity to develop cosmetic products that boost NRF2-mediated antioxidative/antiaging, epidermis-intrinsic bio-responses. PMID: 32982358 [PubMed] (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - September 30, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Consensus Guidelines on Opening Up of Aesthetic Practices in India During the COVID-19 Era.
Conclusion: These recommendations have considered the difficulties and cultural issues faced by aesthetic practices in India. They are user friendly, easy to understand and implement. These guidelines would help in reassuring practices to open up safely and continue serving patients with utmost care. Level of Evidence: Level V, Consensus guidelines. PMID: 32982359 [PubMed] (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - September 30, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

A Case Series: Experience of Using 20% Potassium Hydroxide Solution to Treat Adult Sexually Transmitted Molluscum Contagiosum.
Conclusion: The 20% KOH solution twice daily on MC lesions in adults is effective, practical, and inexpensive. PMID: 32982360 [PubMed] (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - September 30, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Use of a Topical Film-Forming Medical Device Containing Repairsomes ® in a Patient with Xeroderma Pigmentosum to Avoid Progression to Skin Cancerization.
Use of a Topical Film-Forming Medical Device Containing Repairsomes® in a Patient with Xeroderma Pigmentosum to Avoid Progression to Skin Cancerization. Clin Cosmet Investig Dermatol. 2020;13:677-681 Authors: González-Morán A, Piquero-Casals J Abstract This paper reports a case of xeroderma pigmentosum in a 78-year-old woman with a 17-year history of multiple basal cell carcinomas, keratoacanthoma, and lentigo maligna melanoma, in different photoexposed facial regions. To prevent aggravation of these medical conditions, for five years, the patient had been applying a film-forming topi...
Source: Clinical, Cosmetic and Investigational Dermatology - September 30, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Evaluation of the Volumizing Performance of a New Volumizer Filler in Volunteers with Age-Related Midfacial Volume Defects.
Conclusion: The results of the study confirm the esthetic performance of the study product on age-related midfacial volume defects. The very strong high-volumizing activity of the study product was not only properly determined by the investigators but also confirmed by self-evaluation by the volunteers. These effects were obtained with no appreciable undesired effects. PMID: 32982362 [PubMed] (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - September 30, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Patient-Reported Disease Severity and Quality of Life Among Arabic Psoriatic Patients: A Cross-Sectional Survey.
Conclusion: Arabic psoriatic patients participating in this study showed mild to moderate disease severity which had a very large impact on patients' quality of life. Higher disease severity was associated with more impaired quality of life. PMID: 32943898 [PubMed] (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - September 20, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Neuronal Precursor Cell Expressed Developmentally Down Regulated 4 (NEDD4) Gene Polymorphism Contributes to Keloid Development in Egyptian Population.
Conclusion: The polymorphism of the NEDD4 gene rs8032158 could participate in the formation of keloids in the Egyptian population. The NEDD4 rs8032158 CC genotype may have a role in keloid severity. PMID: 32943899 [PubMed] (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - September 20, 2020 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research