A case series evaluating microwave-based therapy for axillary hyperhidrosis and bromhidrosis
CONCLUSION: This novel microwave-based treatment was effective for the treatment of axillary hyperhidrosis and bromhidrosis. Patient satisfaction with the procedure is high, and adverse events are typically transient and well tolerated.PMID:33622150 | DOI:10.1080/09546634.2020.1856317 (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - February 24, 2021 Category: Dermatology Authors: Abdiweli Awil Mohamoud Lina Zeraiq Tine Vestergaard Source Type: research

Mycophenolate mofetil and mycophenolic acid for the treatment of eosinophilic fasciitis: report of two cases and literature review.
We report two EF cases treated effectively with mycophenolate mofetil (MMF) or mycophenolic acid (MPA) and present a literature review. We performed a MEDLINE search using the keywords 'eosinophilic fasciitis', 'Shulman syndrome', 'mycophenolic acid', or 'mofetil mycophenolate', and found 8 articles with 27 cases in which MMF or MPA was used. Twenty-nine cases were reviewed (2 reported herein and 27 from the literature search); all patients received a combination of systemic corticosteroids and MMF. MMF/MPA were given as a steroid-sparing agent in 27 (93.1%), in 1 (3.4%) as adjunctive therapy with other immunosuppressants,...
Source: Journal of Dermatological Treatment - February 23, 2021 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

PASI 100 response rates in moderate to severe psoriasis: a systematic literature review and analysis of clinical practice guidelines.
CONCLUSIONS: PASI 100 response rate is an endpoint fundamentally restricted to research. PMID: 33615959 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - February 23, 2021 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Dupilumab as promising treatment for prurigo nodularis: current evidences.
Authors: Toffoli L, Farinazzo E, Zelin E, Agozzino M, Dianzani C, Di Meo N, Nan K, Zalaudek I, Conforti C Abstract Prurigo nodularis (PN) is a debilitating chronic disease characterized by intense itching and excoriated hyperkeratotic nodules distributed on the trunk and extremities, especially the extensor surfaces. The pathophysiology includes complex and not yet well-understood mechanisms involving inflammation and dysregulation of the nervous system. Currently, there are no approved therapies by the Food and Drug Administration (FDA) and the few treatment approaches for this condition are often ineffective and ...
Source: Journal of Dermatological Treatment - February 17, 2021 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Medicaid and Medicare Part B Spending on Immunomodulators and Biosimilars.
DISCUSSION: Medicare Part-B spending is often overlooked but plays a big role in federal healthcare spending. Exploring the strategic use of less expensive biosimilars could help mitigate spending. PMID: 33577369 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - February 13, 2021 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Artificial hair implantation for hair restoration.
CONCLUSIONS: Artificial hair implantation has been received with skepticism among physicians due to the complications reported. Further high-quality research needs to be performed to ascertain the safety and efficacy of artificial hair implantation. PMID: 33565339 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - February 12, 2021 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

My patient refers smell/taste disturbance. It may not be COVID-19. Dermatological drugs associated with olfactory and/or gustative disorders.
Authors: Castro LGM, Almeida IP PMID: 33565910 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - February 12, 2021 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Analysis of Utilization, Cost and Prescription Trends of Mycophenolate Mofetil and Methotrexate Among Medicare Patients.
Authors: Wang Y, Jorizzo J PMID: 33554688 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - February 10, 2021 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Biologic therapies for plaque type psoriasis in patients with previous malignant cancer: long-term safety in a single- center real-life population.
CONCLUSIONS: Biologic agents in our experience have demonstrated to be safe and effective in psoriatic patients with a past medical history of malignant cancer. PMID: 33555951 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - February 10, 2021 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Efficacy and predictive factors of cyclosporine a in alopecia areata: a systematic review with meta-analysis.
This study aims to determine the most meaningful efficacy of CsA and to reveal features in the therapeutic scheme that help to enhance its efficacy and reduce relapses. METHOD: Efficacy of CsA and predictive factors in the treatment regimen were investigated by systematic review and meta-analysis. Cochrane, MEDLINE, Pubmed and Embase databases were searched. RESULTS: A total of 2.189 papers were retrieved, of which 15 were eligible for the meta-analysis. Based on a total of 344 patients, the mean proportion of responders was 73% (57%-85%). The CsA monotherapy showed a proportion of hair regrowth of 66% (50%-79%), w...
Source: Journal of Dermatological Treatment - February 10, 2021 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Laboratory safety of dupilumab for up to 3 years in adults with moderate-to-severe atopic dermatitis: results from an open-label extension study.
CONCLUSION: Dupilumab treatment of adults with moderate-to-severe AD up to 3 years showed no clinically meaningful changes in mean laboratory parameters, supporting continuous long-term use without laboratory monitoring. CLINICALTRIALS.GOV IDENTIFIER: NCT01949311. PMID: 33557637 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - February 10, 2021 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Treatment of patients with chronic pruritus of unknown origin with dupilumab.
CONCLUSION: This study suggests that dupilumab may be an effective treatment for patients with CPUO and supports the design of future randomized placebo-controlled trials to prove its efficacy. PMID: 33557654 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - February 10, 2021 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Exploring determinants of psoriasis patients' treatment choices: a discrete-choice experiment study in the United States and Germany.
Authors: Feldman SR, Poulos C, Gilloteau I, Mange B, Boehm K, Boeri M, Naatz M, Augustin M Abstract BACKGROUND: Biologic psoriasis treatments are differentiated by efficacy, side effects, and other attributes. OBJECTIVE: Determine attributes of biologic psoriasis treatments that drive patients' treatment choices. METHODS: Respondents (USA: n = 300; Germany: n = 300) with moderate-to-severe psoriasis completed a discrete-choice-experiment survey, choosing between hypothetical treatments characterized by attributes with varying levels: chance of clear skin after 1 year, numb...
Source: Journal of Dermatological Treatment - February 6, 2021 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Immunosuppressants, Immunomodulators and COVID-19 Vaccines: Anticipating Patient Concerns.
Authors: Rick J, Thompson AM, Hsiao JL, Liao W, Shi VY PMID: 33494626 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - January 28, 2021 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Topical corticosteroid withdrawal ("steroid addiction"): An update of a systematic review.
CONCLUSION: Topical corticosteroid withdrawal should be suspected in patients presenting with prolonged usage, erythema, and burning or itch. Patient education and follow up is important to address improper usage. Future studies should focus on comparison group studies to investigate treatment and risk factors. PMID: 33499686 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - January 28, 2021 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Disease burden and treatment history among adults with atopic dermatitis receiving systemic therapy: baseline characteristics of participants on the EUROSTAD prospective observational study.
CONCLUSIONS: Adults with moderate-to-severe AD starting/switching systemic treatment enrolled in EUROSTAD have a high burden of longstanding disease despite continuous use of topical drugs, emollients, and systemic therapies. PMID: 33461356 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - January 21, 2021 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Limb melanomas: acral melanomas have worse survival.
CONCLUSION: Even though they were not found to be correlated with major predictors of poor prognosis, acral melanomas significantly predict poor survival. PMID: 33470132 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - January 21, 2021 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Drug survival of secukinumab, ustekinumab, and certolizumab pegol in psoriasis: a 2-year, monocentric, retrospective study.
Authors: Chatzimichail G, Günther J, Ständer S, Thaçi D Abstract OBJECTIVE: To investigate the drug survival of secukinumab (SEC), ustekinumab (UST), and certolizumab pegol (CZP) in real-world conditions and to identify the predictors and reasons for treatment discontinuation. METHODS: We performed a 2-year retrospective single-center analysis of 110 treatment courses in 98 patients with moderate to severe plaque-type psoriasis and/or psoriatic arthritis (SEC n = 68; UST n = 29; and CZP n = 13). Drug survival was examined using the Kaplan-Meier analysis...
Source: Journal of Dermatological Treatment - January 14, 2021 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Impact of clinical and demographic characteristics on patient preferences for psoriasis treatment features: Results from a discrete-choice experiment in a multicountry study.
CONCLUSION: These many sources of preference heterogeneity identified by our analysis suggest that to improve patient satisfaction and, probably, adherence and persistence, clinicians should discuss options with patients when prescribing their treatment. PMID: 33406942 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - January 8, 2021 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

The impact of Methotrexate therapy with vitamin D supplementation on the cardiovascular risk factors among patients with psoriasis; A prospective randomized comparative study.
CONCLUSION: Treating psoriasis with methotrexate may decrease cardiovascular disease risk factors. Adding vitamin D supplementation to methotrexate may protect lipid homeostasis, specifically cholesterol and triglycerides. PMID: 33390056 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - January 5, 2021 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Dermoscopic evaluation of tranexamic acid versus vitamin C, with microneedling in the treatment of melasma: A comparative, split-face, single-blinded study.
CONCLUSION: Microneedling followed by Vit C or TXA is successful in melasma management, the latter being advantageous vis-a-vis dermal vascularity and epidermal pigmentation. Dermoscopic evaluation appears crucial in choosing optimum treatment in each patient. PMID: 33393842 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - January 5, 2021 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Estimating the susceptibility to SARS-CoV-2 infection with rituximab use for pemphigus vulgaris.
Authors: Jafri ZA, Walia S, Ivanic MG, Wu JJ Abstract The occurrence of the COVID-19 pandemic has raised new uncertainties for dermatologists and their patients, importantly concerning initiation and continuation of immunosuppressants for dermatological conditions at this time. We review two phase III trials of rituximab, a chimeric CD20 monoclonal antibody, used for the treatment of pemphigus vulgaris (PV). Without specific data studying rituximab use and susceptibility of SARS-CoV-2, we hope to utilize available data in order to assist clinician decision making for rituximab in the context of the pandemic. PM...
Source: Journal of Dermatological Treatment - January 1, 2021 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Treating a Chronic Disease without Chronic Adherence.
Authors: Ranpariya V, Balogh EA, Feldman SR PMID: 33355499 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - December 29, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Care and treatment needs of immunosuppressive therapy patients with warts and impact on everyday life - a qualitative study.
CONCLUSIONS: Patients request a person-centred care and treatment approach, to establish a relationship with health care professionals. Establishing care continuity might reduce patients' treatment-related insecurity. PMID: 33356670 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - December 29, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Two-year Follow-up of a Dose Reduction Strategy Trial of Biologics Adalimumab, Etanercept, and Ustekinumab in Psoriasis Patients in Daily Practice.
CONCLUSIONS: The proposed dose reduction strategy is effective for a significant part of patients and remains safe up to two years of follow-up. PMID: 33356686 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - December 29, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

The prevalence of SARS-CoV-2 infection and the severity of the course of COVID-19 in patients with psoriasis treated with biologic therapy.
CONCLUSION: While our study had a small sample size, ongoing biologic treatment in psoriasis was not associated with severe form of COVID-19. PMID: 33317364 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - December 16, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Psoriasis Drugs in the Medicare Population: Dermatologists' Spending and Prescription Patterns.
CONCLUSION: Psoriasis prescriptions comprise a large, increasing proportion of Medicare Part D spending related to dermatology. These increasing costs have significant implications for the healthcare system and affect out-of-pocket costs for patients who rely on such medications. PMID: 33307894 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - December 15, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Time to meaningful clinical response in reduction of itch in atopic dermatitis.
Conclusion: These findings support the role that IL-31 has in producing itch and the role Janus kinase inhibitors (JAKinibs) play in itch reduction. This comparison of TIMEACLIR-Itch for different treatments may help guide therapy and management for AD patients. PMID: 33292019 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - December 11, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Dermatological trends in emergency medicine.
CONCLUSION: The number of ED visits attributed to disease of the skin and subcutaneous tissue has not followed a general trend of increase or decrease. The most common diagnoses are infections. We can best serve these patients by emphasizing the importance of ED provider education on the management of cutaneous infections and by working to increase the accessibility of dermatologic care. PMID: 33267625 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - December 5, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Disease response and patient-reported outcomes among initiators of ixekizumab.
Authors: Shahriari M, Harrison RW, Burge R, Lin CY, Malatestinic WN, Goldblum OM, McLean RR, Crabtree MM, O'Brien J, Grace EL, Mwangi J, Murage Abstract OBJECTIVES: There is limited real-world evidence on using ixekizumab in psoriasis patients. Therefore, we characterized patients with psoriasis initiating ixekizumab and report 6-month changes in disease and patient-reported outcomes. METHODS: Adult patients with psoriasis who initiated ixekizumab and completed a 6-month follow-up visit were enrolled from the Corrona Psoriasis Registry. Disease characteristics and outcomes were assessed at ixekizumab initiation...
Source: Journal of Dermatological Treatment - December 5, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Decoding infraorbital dark circles with lasers and fillers.
CONCLUSIONS: All 3 treatment modalities were effective in the reduction of periorbital dark circles depending on underlying cause. Non-surgical treatments are capable of correcting and improving dark circles with minimum complications and downtime. PMID: 33272039 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - December 5, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Trends and Risk Factors in the Antibiotic Management of Skin and Soft Tissue Infections in the United States.
CONCLUSIONS: This study found that providers more frequently utilize antibiotics with MRSA coverage for SSTIs. Antibiotic class chosen was associated with region, with MRSA coverage antibiotics more likely to prescribed in the South. Additionally, individuals receiving antibiotics with MSSA coverage were older than those receiving antibiotics with MRSA coverage. PMID: 33263454 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - December 4, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Baricitinib improves symptoms in patients with moderate-to-severe atopic dermatitis and inadequate response to topical corticosteroids: patient-reported outcomes from two randomized monotherapy phase III trials.
CONCLUSIONS: Baricitinib significantly improved symptoms in patients with moderate-to-severe AD. CLINICALTRIALS.GOV IDENTIFIERS: NCT03334396 (BREEZE-AD1) and NCT03334422 (BREEZE-AD2). PMID: 33222559 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - November 25, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Platelet-rich plasma for genital lichen sclerosus: analysis and results of 94 patients. Are there gender-related differences in symptoms and therapeutic response to PRP?
CONCLUSIONS: This study demonstrates that PRP based therapy may exert a relevant role in LS patient management due to its effect on Quality of Life (QoL) and sexual function in both gender. In addition, the study underlined gender-related differences in severity of symptoms and disease age onset. PMID: 33226278 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - November 25, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Dupilumab in prurigo nodularis: a systematic review of current evidence and analysis of predictive factors to response.
CONCLUSION: Dupilumab is an effective target-to-treat agent. In comparison with AD, the clinical response to dupilumab initiates later and, two months of therapy are required until significant itch relieves. Complete remission is rarely observed before 4 months of therapy. Notably, AD-related PN patients need longer treatment than non-AD related PN patients to find any relief. Two early signs of improvement are promising predictors of response to dupilumab: The Time_First and NRS_50. PMID: 33200955 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - November 19, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Do increased risks of cancer mean we need to change our approach to treatment?
Authors: Senthilnathan A, Feldman SR PMID: 33143499 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - November 5, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Emerging systemic therapies for atopic dermatitis: oral small molecules and targeted topical agents.
CONCLUSIONS: Targeted therapeutics including oral small molecules and topical agents show promise for the treatment of atopic dermatitis. The use of validated core measures is necessary for future trials in order to adequately compare agents and progress evidence-based medicine. PMID: 33143506 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - November 5, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Cosmetic Skin Lightening Use and Side Effects.
Authors: Masub N, Khachemoune A Abstract Cosmetic skin lightening is a growing dermatologic public health problem that affects communities of color worldwide. Despite well-documented adverse health effects, cosmetic skin lightening continues to be a popular practice among patients of color. Given the US's changing demographics, it is critical for dermatologists to be knowledgeable about the medical impact as well as social and cultural implications of this practice. This review article aims to serve as a primer for the dermatologist on the medical and sociocultural aspects of cosmetic skin lightening, as well as an...
Source: Journal of Dermatological Treatment - November 4, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

The cost of liver function tests for terbinafine: an unnecessary expense.
DISCUSSION: There is a high annual cost of LFTs for patients on terbinafine. As routine LFTs have minimal benefit for detecting DILI3 this cost is a considerable unnecessary expenditure. A limitation of this study is the small sample size in the NAMCS. An analysis of previous years of the NAMCS was not possible due to lack of documentation of LFTs prior to 2014. PMID: 33103507 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - October 27, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

COVID-19 in 3 patients treated with immune checkpoint inhibitors for advanced melanoma.
Authors: Arenbergerova M, Gkalpakiotis S, Arenberger P, Fialova A, Pasek M PMID: 33092421 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - October 25, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Treatment of basal cell carcinomas and basaloid follicular hamartomas in basal cell nevus syndrome children and adolescents.
Authors: Verkouteren BJA, Mosterd K PMID: 33081541 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - October 23, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Antihistamines-refractory chronic pruritus in psoriatic patients undergoing biologics: Aprepitant Vs Antihistamine double dosage, a real-world data.
Authors: Damiani G, Kridin K, Pacifico A, Malagoli P, Dm Pigatto P, Finelli R, Taccone FS, Peluso L, Conic RRZ, Bragazzi NL, Dermatologists Italian Network Y, Fiore M Abstract BACKGROUND: Psoriasis-related pruritus-(PRP) in patients under systemic treatment is challenging. The risk to switch anti-psoriatic drug and to lose response to previous therapy is high, thus dermatologists prefer to add an anti-pruritic agent. OBJECTIVES: To evaluate the effect of anti-histamines and aprepitant in treating PPR of psoriatic patients undergoing systemic anti-psoriatic therapies. METHODS: A pilot observational open-labe...
Source: Journal of Dermatological Treatment - October 23, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Clinical efficacy and safety of secukinumab for psoriasis in a real-world setting in turkey.
CONCLUSION: Our results are in line with the efficacy and safety profiles of secukinumab in PsO reported previously. Dose escalation and the addition of concomitant medications may increase response rates. PMID: 33074062 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - October 22, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Spotlight on the Treatment Armamentarium of Concomitant Psoriasis and Inflammatory Bowel Disease: A Systematic Review.
Conclusions: Psoriasis and IBD can be treated concurrently as they share common inflammatory pathways. TNF-α inhibitors and IL-12/23 have been successful in treating both psoriasis and IBD. IL-17 inhibitors are recognized treatments for psoriasis but have the potential to exacerbate IBD. Newer molecules require further clinical trials and real-life studies in order to confirm their efficacy and safety. PMID: 33074781 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - October 22, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Systemic ketoconazole continues to be prescribed despite an FDA warning.
Authors: Muddasani S, Peck G, Fleischer AB PMID: 33076731 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - October 22, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Strategies to maximize clinical efficiency while maintaining patient safety during the COVID-19 pandemic: an interview-based study from private practice dermatologists.
CONCLUSION: Improving patient communication, implementing protocols to facilitate social distancing, and utilizing teledermatology were reported to be essential to optimizing efficiency and safety. As the COVID-19 pandemic continues to evolve, it is important that dermatologists identify specific ways to practice efficiently and effectively, while mitigating the spread of the virus. PMID: 33054453 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - October 20, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Critical Incidence Reporting in Dermatology: A Cross-Sectional Study of 94 Cases in a Tertiary Referral Centre.
DISCUSSION: Critical incidents in dermatological clinical routine are potentially severe, they most commonly involve medication errors, personal factors and communication errors. More than a third of all cases resulted in a potentially severe consequence, with the likelihood of reoccurrence of>90%. PMID: 33073663 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - October 20, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Beneficial Effect of Lactobacillus plantarum IS-10506 Supplementation in Adults with Atopic Dermatitis: A Randomized Controlled Trial.
Conclusion: The administration of LP IS-10506 is effective for alleviating AD symptoms in adults owing to its immunomodulatory effects. PMID: 33040631 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - October 15, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Rituximab monotherapy in mild pemphigus.
Authors: Nili A, Mahmoudi H, Heidari N, Tavakolpour S, Salehi Farid A, Balighi K, Daneshpazhooh M PMID: 33040641 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - October 15, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research