Treatment of basal cell carcinomas and basaloid follicular hamartomas in basal cell nevus syndrome children and adolescents.
Authors: Verkouteren BJA, Mosterd K PMID: 33081541 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - October 23, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Antihistamines-refractory chronic pruritus in psoriatic patients undergoing biologics: Aprepitant Vs Antihistamine double dosage, a real-world data.
Authors: Damiani G, Kridin K, Pacifico A, Malagoli P, Dm Pigatto P, Finelli R, Taccone FS, Peluso L, Conic RRZ, Bragazzi NL, Dermatologists Italian Network Y, Fiore M Abstract BACKGROUND: Psoriasis-related pruritus-(PRP) in patients under systemic treatment is challenging. The risk to switch anti-psoriatic drug and to lose response to previous therapy is high, thus dermatologists prefer to add an anti-pruritic agent. OBJECTIVES: To evaluate the effect of anti-histamines and aprepitant in treating PPR of psoriatic patients undergoing systemic anti-psoriatic therapies. METHODS: A pilot observational open-labe...
Source: Journal of Dermatological Treatment - October 23, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Clinical efficacy and safety of secukinumab for psoriasis in a real-world setting in turkey.
CONCLUSION: Our results are in line with the efficacy and safety profiles of secukinumab in PsO reported previously. Dose escalation and the addition of concomitant medications may increase response rates. PMID: 33074062 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - October 22, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Spotlight on the Treatment Armamentarium of Concomitant Psoriasis and Inflammatory Bowel Disease: A Systematic Review.
Conclusions: Psoriasis and IBD can be treated concurrently as they share common inflammatory pathways. TNF-α inhibitors and IL-12/23 have been successful in treating both psoriasis and IBD. IL-17 inhibitors are recognized treatments for psoriasis but have the potential to exacerbate IBD. Newer molecules require further clinical trials and real-life studies in order to confirm their efficacy and safety. PMID: 33074781 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - October 22, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Systemic ketoconazole continues to be prescribed despite an FDA warning.
Authors: Muddasani S, Peck G, Fleischer AB PMID: 33076731 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - October 22, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Strategies to maximize clinical efficiency while maintaining patient safety during the COVID-19 pandemic: an interview-based study from private practice dermatologists.
CONCLUSION: Improving patient communication, implementing protocols to facilitate social distancing, and utilizing teledermatology were reported to be essential to optimizing efficiency and safety. As the COVID-19 pandemic continues to evolve, it is important that dermatologists identify specific ways to practice efficiently and effectively, while mitigating the spread of the virus. PMID: 33054453 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - October 20, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Critical Incidence Reporting in Dermatology: A Cross-Sectional Study of 94 Cases in a Tertiary Referral Centre.
DISCUSSION: Critical incidents in dermatological clinical routine are potentially severe, they most commonly involve medication errors, personal factors and communication errors. More than a third of all cases resulted in a potentially severe consequence, with the likelihood of reoccurrence of>90%. PMID: 33073663 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - October 20, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Beneficial Effect of Lactobacillus plantarum IS-10506 Supplementation in Adults with Atopic Dermatitis: A Randomized Controlled Trial.
Conclusion: The administration of LP IS-10506 is effective for alleviating AD symptoms in adults owing to its immunomodulatory effects. PMID: 33040631 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - October 15, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Rituximab monotherapy in mild pemphigus.
Authors: Nili A, Mahmoudi H, Heidari N, Tavakolpour S, Salehi Farid A, Balighi K, Daneshpazhooh M PMID: 33040641 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - October 15, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Who Sees you Matters: A Population Study Examining Topical Corticosteroid Prescribing Patterns between Primary Care Providers and Dermatologists for Atopic Dermatitis.
Conclusions: Atopic dermatitis patients seen by internal medicine physicians are much less likely to receive topical corticosteroid prescriptions as compared to those seen by dermatologists. PMID: 33043730 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - October 15, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Emerging Systemic Therapies for Atopic Dermatitis: Biologics.
Conclusions: The growing class of biologics shows promise in meeting the needs of treatment-resistant atopic dermatitis. The use of validated core measurements is necessary for future trials in order to adequately compare agents and progress evidence-based medicine. PMID: 33045848 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - October 15, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Clinical efficacy and safety of secukinumab in patients with psoriasis and comorbidities: pooled analysis of 4 phase 3 clinical trials.
Authors: Gottlieb AB, Wu JJ, Griffiths CEM, Marfo K, Muscianisi E, Meng X, Frueh J, Lebwohl M Abstract Background: The influence of comorbidities on the efficacy and safety of biologic therapies in psoriasis has not been rigorously explored.Objective: To assess the incremental burden of comorbidities on clinical efficacy and safety of secukinumab vs etanercept and placebo among patients with plaque psoriasis pooled from 4 phase 3 trials.Methods: Efficacy was assessed at week 12 according to achievement of Psoriasis Area and Severity Index (PASI) and Investigator's Global Assessment (IGA; modified 2011) responses. E...
Source: Journal of Dermatological Treatment - October 9, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Quantifying Patient Preferences for Systemic Atopic Dermatitis Treatments Using a Discrete-Choice Experiment.
Conclusion: The findings of this study can help inform joint patient-physician decision making in managing moderate-to-severe AD. PMID: 33023361 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - October 9, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

A Retrospective Study Comparing Different Injection Approaches of 5-Aminolevulinic Acid in Patients with Non-Melanoma Skin Cancer.
Conclusions: Needle-free injection of intralesional 5-aminolevulinic acid followed by irradiation with red light therapy were reported high treatment response with manageable adverse effects for non-melanoma skin cancer patients than that of conventional and plum-blossom needle injections.Level of Evidence: III. PMID: 33016837 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - October 7, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

The eye area as the most difficult area of activity for aesthetic treatment.
This article also presents treatment methods in the field of aesthetic dermatology, which are used in the in the following problems: eyelid edema, fatty bags under the eyes, vascular circles under the eyes, pigment shadows, periorbital melanosis, structural shadows, tear trough, wrinkles and loss of skin elasticity and dry skin around the eyes. Their correct diagnosis requires the knowledge of the characteristics of the skin structure within the eye area and also the mechanisms responsible for disorders in its functioning. Many patients and people performing procedures, limit the problems within eye area to a generalized d...
Source: Journal of Dermatological Treatment - October 7, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Management Strategies for Borderline and Narcissistic Personality Disorders in Dermatology Practice: A Review.
Authors: Reddy V, Myers B, Chan S, Brownstone N, Thibodeaux Q, Koo J Abstract Dermatologists are often ill-equipped to promptly identify and manage patients with personality disorders. Patients with borderline personality disorder (BPD) and narcissistic personality disorder (NPD) frequently present to dermatology clinics, particularly those that provide aesthetic services. Although dermatologists should ideally utilize specific management strategies when working with these patients, there is a lack of awareness and availability of resources on how to do so. Here, we review the psychiatry, plastic and reconstructive...
Source: Journal of Dermatological Treatment - October 7, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Dermatologists are increasing their use of non-opioid pain medications faster than opioids.
Authors: Muddasani S, Peck G, Fleischer AB Abstract Introduction: There is a lack of consensus in the literature on how and when dermatologists prescribe pain medications. As there is an ongoing opioid abuse epidemic driven by prescription opioids, it is important for all fields to investigate their own prescribing patterns.Methods: We analyzed the National Ambulatory Medical Care Survey from 2007 to 2016 to assess the usage of systemic pain medications amongst dermatologists.Results: There were 16,777 total visits with dermatologists which represents 368 (95% confidence interval 363, 373) million estimated visits....
Source: Journal of Dermatological Treatment - October 7, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Dermatologists on the Medical Need for Therapeutic Drug Monitoring of Biologics in Psoriasis: Results of a Structured Survey.
Conclusion: This study showed most dermatologists perform dose adaptations empirically. The need for TDM was indicated by the majority, implying the need for effective communication regarding availability, utility and implementation of TDM assays in daily dermatology practice. PMID: 33019835 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - October 7, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Striae gravidarum and different modalities of therapy: a review and update.
Authors: Yu Y, Wu H, Yin H, Lu Q Abstract The term striae gravidarum (SG) refers to a kind of striae distensae (SD) that develops particularly during pregnancy. According to the level of maturity of the lesions, SG is divided into striae rubra (SR) and striae alba (SA). The pathogenesis remains unclear; recent studies have implicated abnormalities in elastic fibers, collagen fibrils, and other extracellular matrix (ECM) components. Changes in the expression of hormone receptors and hormone levels have also been hypothesized. Considering this new information, we reviewed successful treatments of SG and listed them i...
Source: Journal of Dermatological Treatment - October 3, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Do increased risks of cancer mean we need to change our approach to treatment?
Authors: Senthilnathan A, Feldman SR PMID: 32997562 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - October 1, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Evaluating the effect of oral clarithromycin on acute cutaneous leishmaniasis lesions compared with systemic glucantime.
CONCLUSIONS: We concluded oral clarithromycin had therapeutic effects on acute CL similar to systematic glucantime and could be considered as a safe and effective treatment option. PMID: 32972289 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - September 27, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Self-perceived disease control in childhood eczema.
Authors: Lam PH, Hon KL, Leung K, Leong KF, Li CK, Leung TF Abstract BACKGROUND: Atopic eczema (AE) is a common relapsing inflammatory skin disease in children which is often associated with chronicity and poor quality of life. Unlike atopic asthma, control of AE is seldom assessed in therapeutics. AIM: To investigate the utility of a Traffic Light Control (TLC) system as a measurement/assessment of self-perceived eczema control. METHODS: This is a prospectively study of all Chinese children (aged 6 to 18 years old) with eczema attending the paediatric dermatology clinic of a tertiary hospital from Jan to J...
Source: Journal of Dermatological Treatment - September 24, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Epidemilogy of moderate-to-severe psoriasis: a comparison between psoriasis patients treated with biological agents, conventional systemic drugs and topical agents.
Authors: Marques E, Paluch Z, Boháč P, Slanař O, Běláček J, Hercogová J Abstract INTRODUCTION: Understanding how different comorbidities and epidemiological factors are related to psoriasis severity can help us estimating patients' clinical outcome. AIM: Establish possible prognostic factors of severe psoriasis. METHODS: Three groups of patients were included: 118 were on topical therapy, 83 used conventional systemic drugs and 112 were treated with biological agents. Based of the fact that patients on topical therapy have a lower grade of disease severity than patients treated syst...
Source: Journal of Dermatological Treatment - September 24, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Glucagon-like peptide-1 receptor agonist liraglutide therapy for psoriasis patients with type 2 diabetes: a randomized-controlled trial.
Authors: Lin L, Xu X, Yu Y, Ye H, He X, Chen S, Chen X, Shao Z, Chen P Abstract Objective: There were some clinical studies on GLP-1R agonist liraglutide therapy for psoriasis patients with type 2 diabetes, but there is a lack of randomized controlled trials and the mechanism of which remains unclear.Method: A total of 25 psoriasis patients with type 2 diabetes were randomized 1: 1 divided into the control group (n = 13) or liraglutide group (n = 12) for 12 weeks. We determined the PASI, the DLQI, histopathology of psoriasis skin, and the expression of IL-17, IL-23, and TNF-α in th...
Source: Journal of Dermatological Treatment - September 24, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Comparison of psoriasis guidelines for use of IL-23 inhibitors in the United States and United Kingdom: A critical appraisal and comprehensive review.
Conclusion: IL-23 inhibitors are safe and efficacious therapeutic options for patients with psoriasis and should be considered as a potential first-line therapy alone or in combination with topical medications, phototherapy, and other systemic non-biologic agents. Consideration should be given to the evidence-based guidelines of global dermatologic organizations to help guide therapeutic decisions. PMID: 32962478 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - September 24, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Why is Pimozide Uniquely Useful for the Treatment of Delusional Patients in Dermatology?
Authors: Brownstone N, Koo J PMID: 32940111 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - September 19, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

An assessment of current practices in hidradenitis suppurativa: the rise of biologic therapy.
Discussion: The use of biologic agents did not increase in this interval, but it is higher than in an earlier assessment of the NAMCS. Nearly all systemic immunomodulators are prescribed by dermatologists. The ambulatory uptake of these agents did not alter the use of other treatment modalities within this timeframe. PMID: 32940551 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - September 19, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Language proficiency and biologics access: a population study of psoriasis patients in the United States.
CONCLUSIONS: Psoriasis patients with low English proficiency are significantly less likely to receive biologics than those with high English proficiency. Those with higher English proficiency are 61 times more likely to access biologics. PMID: 32928008 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - September 17, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) with probable mesentery involvement with associated hemophagocytic syndrome (HPS) - how to treat it?
Authors: Giza A, Gałązka K, Jońca M, Raźny M, Zimowska-Curyło D, Wilk M, Goldman-Mazur S, Piątkowska-Jakubas B, Sacha T Abstract Subcutaneous panniculitis-like T-cell lymphoma (SPTL) is a rare, cutaneous lymphoma involving subcutaneous adipose tissue. SPTL is associated in less than 20% with hemophagocytic syndrome (HPS). A 5-year overall survival rate is inferior in pts with SPTLand HPS (46%) as compared with 91% in pts without HPS. No standardized therapy for SPTCL has yet been established. A case of 35-year-old Caucasian man with a one-month history of B symptoms with the suspicion of Still's disease. At a...
Source: Journal of Dermatological Treatment - September 16, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Pain Management Modalities for Hidradenitis Suppurativa: A Patient Survey.
Conclusions and Relevance: Even the highest-rated pain management modalities are considered only moderately effective by HS patients. PMID: 32914659 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - September 13, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Correction.
Authors: PMID: 32896178 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - September 10, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Unmet needs in patients with moderate-to-severe plaque psoriasis treated with methotrexate in real world practice: FirST study.
CONCLUSIONS: The study identified unmet needs in moderate-to-severe plaque psoriasis patients treated with MTX, revealing a significant proportion of sub-optimally controlled patients in terms of HRQoL and different domains of the disease. This study also found patients at-risk of advanced fibrosis, with evidence suggesting a correlation between longer exposures to MTX and higher risk of advanced fibrosis. PMID: 32900254 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - September 10, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Human mesenchymal stem cell-derived exosomes accelerate wound healing of mice eczema.
Authors: Wang M, Zhao Y, Zhang Q Abstract Introduction: The aim of our study was to investigate the therapeutic effect of Mesenchymal stem cell-derived exosomes(MSC-exs)on eczema mice model.Methods: Eczema mice were established by 2, 4- two nitrochlorobenzene (DNCB). Human umbilical cords (UC) cells and exosomes were harvested. In eczema mice model, the effect of MSC-ex on eczema was evaluated by severity score, atopic dermatitis (SCORAD) score and histopathological analysis of dermis. MTT tests were performed to assess PBMC proliferation. Treg was identified by flow cytometry. The angiogenesis was analyzed by endo...
Source: Journal of Dermatological Treatment - September 9, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Efficacy and safety of fractional CO2 laser and tranexamic acid versus microneedling and tranexamic acid in the treatment of infraorbital hyperpigmentation.
Authors: Ghandehari R, Robati RM, Niknezhad N, Hajizadeh N, Tehranchinia Z Abstract Objective: To compare the efficacy and safety of microneedling and fractional CO2 laser in combination with tranexamic acid in the treatment of infra-orbital hyperpigmentation.Patients/Methods: This split-face clinical trial performed on 30 volunteers. The patients were randomly assigned to treat with fractional CO2 laser and microneedling, both combined with tranexamic acid topically. Three monthly treatment sessions were performed. Two blinded dermatologists evaluated the response after each treatment session and one and three mon...
Source: Journal of Dermatological Treatment - September 9, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Efficacy of curcumin for recurrent aphthous stomatitis: a systematic review.
Conclusion: The limited available evidence suggests that curcumin have potential benefits in alleviating pain and accelerating healing in patients with RAS. Further well-designed clinical trials with standardized curcumin formulations are highly recommended. PMID: 32893718 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - September 9, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Evaluation of anxiety and depression in patients with morphea taking immunosuppressive drugs during the COVID-19 pandemic.
Conclusion: Although there was no significant difference in anxiety and depression between the groups, it is recommended to provide the opportunity for psychiatric counselling to improve treatment outcomes during this pandemic. PMID: 32893725 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - September 9, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Correlation of serum Vitamin D levels with severity of pediatric atopic dermatitis and the impact of Vitamin D supplementation on treatment outcomes.
Conclusion: We found no difference in the mean serum vitamin D levels between atopic dermatitis patients and controls. An inverse correlation was seen between serum vitamin D levels at baseline and severity of atopic dermatitis. Beneficial effect of vitamin D supplementation was observed maximally in severe AD as observed by a reduction in SCORAD. PMID: 32885699 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - September 6, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Long-Term Outcomes of Crystallized Phenol Application for the Treatment of Pilonidal Sinus Disease.
Conclusion: Long-term outcomes are also very successful in the treatment of pilonidal disease with crystallized phenol treatment. We believe that crystallized phenol treatment should be the first choice in the treatment of pilonidal disease because it is inexpensive, can be applied as an outpatient treatment, is a non-invasive procedure, has results comparable to surgical procedures, and does not cause loss of work and strength. PMID: 32885705 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - September 6, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Treatment of Keratosis Pilaris and Its Variants: A Systematic Review.
Conclusion: While the measured treatment outcomes varied among studies, laser therapy appeared most efficacious in the treatment of KP and its subtypes. Usage of topical treatments also improved KP lesions. PMID: 32886029 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - September 6, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Long-term vemurafenib therapy in advanced melanoma patients: cutaneous toxicity and prognostic implications.
Conclusions: Among long-term survivors, skin AEs seem to be less frequent and less severe. Results on multivariable analysis revealed that the presence of at least one G2 toxicity is a protective factor considering PFS, but not in terms of OS. PMID: 32875931 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - September 4, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Comparing efficacy and safety of potassium hydroxide 5% solution with 5-fluorouracil cream in patients with actinic keratoses: a randomized controlled trial.
Authors: Salehi Farid A, Niknam S, Gholami K, Tavakolpour S, Teimourpour A, Daneshpazhooh M, Nili A, Azizpour A, Nasimi M, Mahmoudi H Abstract Background: Actinic keratosis (AK) is a pre-cancerous skin lesion, associated with development of squamous cell carcinoma. Current treatment options are limitedObjectives: To compare the efficacy and safety of topical 5-fluorouracil cream (5-FU) and potassium hydroxide 5% (KOH) in the treatment of AK.Methods: Eighteen patients with AK applied KOH solution or 5-FU on each side of their scalp/face, randomly. The efficacy and safety of these treatments were compared.Results: Th...
Source: Journal of Dermatological Treatment - September 4, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Urticaria and COVID-19 infection: a critical appraisal- Reply.
Authors: Shanshal M PMID: 32878508 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - September 4, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

The reduction in the detection of melanoma during the coronavirus disease 2019 (COVID-19) pandemic in a Melanoma center of South Italy.
Authors: Villani A, Fabbrocini G, Scalvenzi M PMID: 32878522 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - September 4, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Efficacy and safety of tretinoin 0.05% cream to prevent hyperpigmentation during narrowband UV-B phototherapy in patients with facial vitiligo: A randomized clinical trial.
Conclusions: Tretinoin 0.05% cream prevented hyperpigmentation during NBUVB phototherapy in patients with facial vitiligo, and did not compromise the overall treatment response.Trial registration: ClinicalTrials.gov NCT03933774. PMID: 32869680 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - September 3, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Factors affecting vitiligo response to treatment: do MiRNA 196a2C/T gene polymorphism and serum tyrosinase levels have any role?
CONCLUSION: MiRNA 196a-2 C/T (11614913) gene polymorphism and the elevated serum tyrosinase levels might be related to the pathogenesis of vitiligo and may affect its therapeutic response. PMID: 32838589 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - August 27, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Onychomycosis in Children - Review on treatment and management strategies.
Authors: Gupta AK, Venkataraman M, Shear NH, Piguet V Abstract Background: Onychomycosis is an uncommon condition in children with increasing global prevalence. Health practitioners should confirm the diagnosis through mycology examination and examine family members of affected individuals for onychomycosis and tinea pedis.Objective: To comprehensively summarize the treatment and management strategies for pediatric onychomycosis.Methods: We performed a comprehensive literature search in the PubMed database to identify clinical studies on treatment for mycologically-confirmed dermatophyte onychomycosis in children
Source: Journal of Dermatological Treatment - August 18, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Vitamin D status in patients with autoimmune bullous dermatoses: A meta-analysis.
Conclusions: Abnormal vitamin D status are more common in AIBD patients than that in general population. Therefore, regular monitoring of vitamin D levels and vitamin D supplementation should be considered as part of the management strategy for AIBD. PMID: 32799714 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - August 18, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Dermatological Innovations in three directions.
Authors: van de Kerkhof PC PMID: 32783518 [PubMed - in process] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - August 14, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Psychological teleconsultations in patients suffering from chronic skin diseases during the COVID-19 era: a service to improve patients' quality of life.
Authors: Marasca C, De Rosa A, Fabbrocini G, Cantelli M, Patrì A, Vastarella M, Gallo L, di Vico F, Poggi S, Ruggiero A Abstract The COVID-19 era represented an important stressful event affecting population in many different ways, with important negative impact on social, working and relational life. Indeed, the home-isolation in addition to the high-level of distress given by fear of infection, has significantly resulted in a large number of psychological-consequences. Moreover, in order to guarantee a continuity of care, different measures have been applied among hospitals such as the implementation of te...
Source: Journal of Dermatological Treatment - August 14, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Elderly patients with psoriasis: Long-term efficacy and safety of modern treatments.
Conclusions: Biologicals and apremilast demonstrate adequate efficacy in elderly psoriatic patients. Incidence and severity of reported adverse events were similar to those reported among patients of younger age in relevant clinical studies. PMID: 32783678 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - August 14, 2020 Category: Dermatology Tags: J Dermatolog Treat Source Type: research