The Association between Histidine-Rich Glycoprotein rs10770 Genotype and Recurrent Miscarriage in Iranian Women
CONCLUSION: The study highlights the importance of HRG rs10770 in understanding RM, shedding light on its implications for reproductive health. Furthermore, it became evident that women carrying the homozygous C/C genotype exhibited increased susceptibility to the risk of RM.PMID:38659607 | PMC:PMC11042909 | DOI:10.1155/2024/2501086 (Source: Biomed Res)
Source: Biomed Res - April 25, 2024 Category: Research Authors: Mahbobeh Latifimehr Leila Nazari Ali Asghar Rastegari Zahra Zamani Pezhman Fard-Esfahani Source Type: research

A Bibliometric Analysis of Study of Associations of Certain Genotypes with the Cardiovascular Form of Diabetic Neuropathy
Biomed Res Int. 2024 Apr 15;2024:6761451. doi: 10.1155/2024/6761451. eCollection 2024.ABSTRACTThis bibliometric analysis explores the landscape of research on the associations between specific genotypes and the cardiovascular form of diabetic neuropathy. Diabetes mellitus (DM) is a major contributor to premature mortality, primarily due to increased susceptibility to cardiovascular diseases. The global prevalence of DM is rising, with projections indicating further increases. Diabetic neuropathy, a complication of DM, includes the cardiovascular subtype, posing challenges in diagnosis and management. Understanding the gene...
Source: Biomed Res - April 25, 2024 Category: Research Authors: Nazira B Bekenova Tamara A Vochshenkova Nurgul Ablakimova Aliya Zhylkybekova Nadiar M Mussin Rustam K Albayev Asset A Kaliyev Amin Tamadon Source Type: research

Development of a performance-based toolkit of the treatable traits of functioning in hospitalised patients with exacerbation of COPD: a survey-based study protocol
CONCLUSION: The development of a feasible performance-based toolkit with the best markers for each key treatable trait of functioning in hospitalised patients with ECOPD will make it possible to create individualised patient care for the specific demands of these patients.PMID:38651092 | PMC:PMC11033727 | DOI:10.1183/23120541.00809-2023 (Source: Biomed Res)
Source: Biomed Res - April 23, 2024 Category: Research Authors: Naiara Tais Leonardi D ébora Mayumi Oliveira Kawakami Joana Cruz Chris Burtin Audrey Borghi-Silva Renata Gon çalves Mendes Source Type: research

Development of a performance-based toolkit of the treatable traits of functioning in hospitalised patients with exacerbation of COPD: a survey-based study protocol
CONCLUSION: The development of a feasible performance-based toolkit with the best markers for each key treatable trait of functioning in hospitalised patients with ECOPD will make it possible to create individualised patient care for the specific demands of these patients.PMID:38651092 | PMC:PMC11033727 | DOI:10.1183/23120541.00809-2023 (Source: Biomed Res)
Source: Biomed Res - April 23, 2024 Category: Research Authors: Naiara Tais Leonardi D ébora Mayumi Oliveira Kawakami Joana Cruz Chris Burtin Audrey Borghi-Silva Renata Gon çalves Mendes Source Type: research

Injectable bioactive poly(propylene fumarate) and polycaprolactone based click chemistry bone cement for spinal fusion in rabbits
In this study, we fabricated an injectable bioactive click chemistry polymer cement for use in spinal fusion and bone regrowth. Taking advantages of the bioorthogonal click reaction, this cement can be crosslinked by itself eliminating the addition of a toxic initiator or catalyst, nor any external energy sources like UV light or heat. Furthermore, nano-hydroxyapatite (nHA) and microspheres carrying recombinant human bone morphogenetic protein-2 (rhBMP-2) and recombinant human vascular endothelial growth factor (rhVEGF) were used to make the cement bioactive for vascular induction and osteointegration. After implantation i...
Source: Biomed Res - April 22, 2024 Category: Research Authors: Xifeng Liu Maria D Astudillo Potes Vitalii Serdiuk Babak Dashtdar Areonna C Schreiber Asghar Rezaei A Lee Miller Abdelrahman M Hamouda Mahnoor Shafi Benjamin D Elder Lichun Lu Source Type: research

Efficacy evaluation of standardized < em > Rheum rhaponticum < /em > root extract (ERr 731 < sup > ® < /sup > ) on symptoms of menopause: A systematic review and meta-analysis study
J Biomed Res. 2024 Apr 18:1-9. doi: 10.7555/JBR.37.20230219. Online ahead of print.ABSTRACTMenopause is characterized by various physical, mental and emotional symptoms. ERr 731 ® is a standardized extract from Rheum rhaponticum root and has been clinically studied for its role in reducing menopausal symptoms. The current systematic review and meta-analysis aimed to evaluate the efficacy of ERr 731 ® supplementation in alleviating the severity of menopausal symptoms. In this review, we searched across three online databases up to March 2023, evaluated the quality of the included studies by the Physiotherapy Evidence Data...
Source: Biomed Res - April 22, 2024 Category: Research Authors: Vishal P Dubey Varun P Sureja Dharmeshkumar B Kheni Source Type: research

Mitochondrial Physiology of Cellular Redox Regulations
Physiol Res. 2024 Apr 22. Online ahead of print.ABSTRACTMitochondria (mt) represent the vital hub of the molecular physiology of the cell, being decision-makers in cell life/death and information signaling, including major redox regulations and redox signaling. Now we review recent advances in understanding mitochondrial redox homeostasis, including superoxide sources and H2O2 consumers, i.e., antioxidant mechanisms, as well as exemplar situations of physiological redox signaling, including the intramitochondrial one and mt-to-cytosol redox signals, which may be classified as acute and long-term signals. This review exempl...
Source: Biomed Res - April 22, 2024 Category: Research Authors: P Je žek A Dlaskov á H Engstov á J Špačková J Tauber P Pr ůchová E Kloppel O Mozheitova M Jab ůrek Source Type: research

Locally released dexamethasone and its effects on osteogenic activity at implant-tissue interface
This study emphasizes the promising implications for functionalizing surfaces of implant materials with DEX-loaded chitosan microspheres to improve their biocompatibility and bioactivity.PMID:38642019 | DOI:10.1002/jbm.a.37722 (Source: Biomed Res)
Source: Biomed Res - April 20, 2024 Category: Research Authors: Gizem Kerem Sakip Önder Abdulhalim K ılıç Source Type: research

Knowledge, Perception, and Practice of Safe Medical Circumcision on HIV Infection Risk Reduction among Undergraduate Students of a Public University in Northern Uganda: A Cross-Sectional Study
CONCLUSIONS: More than three in four of the undergraduate students have knowledge on safe medical circumcision as risk reduction measure for HIV infection. And close to 3 in 4 (74.46%) of the student's perception were unsure if they would opt for safe medical circumcision as risk reduction measure against HIV. The practice of safe medical circumcision was 64.8% among the study participants. Therefore, in an effort to increase SMC's adoption for HIV/AIDS prevention, the Ministry of Health of Uganda and related stakeholders in health should work hand in hand with university study bodies in order to optimize SMC uptake among ...
Source: Biomed Res - April 18, 2024 Category: Research Authors: Lucky Akugizibwe Deo Benyumiza Catherine Nekesa Edward Kumakech Eustes Kigongo Nasser Ashaba Amir Kabunga Raymond Tumwesigye Source Type: research

Perception of Healthcare Professionals towards Electronic-Prescribing at University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia: A Cross-Sectional Study
Conclusion and Recommendation. The majority of healthcare professionals had a neutral perception of e-prescribing. The perception of healthcare professionals differs based on their qualifications, work and computer use experience, and their exposure to e-prescribing. The hospital should take all expectations and concerns of all HCPs into consideration and provide experience-sharing opportunities for all healthcare professionals who may potentially be involved in e-prescribing.PMID:38633242 | PMC:PMC11022515 | DOI:10.1155/2024/6553470 (Source: Biomed Res)
Source: Biomed Res - April 18, 2024 Category: Research Authors: Faisel Dula Sema Abel Getu Kebede Girum Zeleke Soworsu Tigist Tsegaye Mengistu Hussien Endris Assen Esileman Abdela Muche Rahel Belete Abebe Leila Kenzu Kemal Abdisa Gemedi Jara Abdulwase Mohammed Seid Source Type: research

A Systematic Guideline by the ASPN Workgroup on the Evidence, Education, and Treatment Algorithm for Painful Diabetic Neuropathy: SWEET
CONCLUSION: The ASPN SWEET Guideline represents the most comprehensive review of the available treatments for PDN and their appropriate and safe utilization.PMID:38633823 | PMC:PMC11022879 | DOI:10.2147/JPR.S451006 (Source: Biomed Res)
Source: Biomed Res - April 18, 2024 Category: Research Authors: Dawood Sayed Timothy Ray Deer Jonathan M Hagedorn Asim Sayed Ryan S D'Souza Christopher M Lam Nasir Khatri Zohra Hussaini Scott G Pritzlaff Newaj Mohammad Abdullah Vinicius Tieppo Francio Steven Michael Falowski Yussr M Ibrahim Mark N Malinowski Ryan R Bu Source Type: research

Sixty Years of Heart Research in the Institute of Physiology of the Czech Academy of Sciences
The objective of this review is to succinctly illuminate the scientific trajectory of an experimental cardiological department over a 60-year span, from its inaugural publication to the present. The old truth - historia magistra vitae - is still valid. Keywords: Heart, Adaptation, Development, Hypoxia, Protection.PMID:38634652 (Source: Biomed Res)
Source: Biomed Res - April 18, 2024 Category: Research Authors: B Ostadal F Kolar Source Type: research

Knowledge, Perception, and Practice of Safe Medical Circumcision on HIV Infection Risk Reduction among Undergraduate Students of a Public University in Northern Uganda: A Cross-Sectional Study
CONCLUSIONS: More than three in four of the undergraduate students have knowledge on safe medical circumcision as risk reduction measure for HIV infection. And close to 3 in 4 (74.46%) of the student's perception were unsure if they would opt for safe medical circumcision as risk reduction measure against HIV. The practice of safe medical circumcision was 64.8% among the study participants. Therefore, in an effort to increase SMC's adoption for HIV/AIDS prevention, the Ministry of Health of Uganda and related stakeholders in health should work hand in hand with university study bodies in order to optimize SMC uptake among ...
Source: Biomed Res - April 18, 2024 Category: Research Authors: Lucky Akugizibwe Deo Benyumiza Catherine Nekesa Edward Kumakech Eustes Kigongo Nasser Ashaba Amir Kabunga Raymond Tumwesigye Source Type: research

Perception of Healthcare Professionals towards Electronic-Prescribing at University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia: A Cross-Sectional Study
Conclusion and Recommendation. The majority of healthcare professionals had a neutral perception of e-prescribing. The perception of healthcare professionals differs based on their qualifications, work and computer use experience, and their exposure to e-prescribing. The hospital should take all expectations and concerns of all HCPs into consideration and provide experience-sharing opportunities for all healthcare professionals who may potentially be involved in e-prescribing.PMID:38633242 | PMC:PMC11022515 | DOI:10.1155/2024/6553470 (Source: Biomed Res)
Source: Biomed Res - April 18, 2024 Category: Research Authors: Faisel Dula Sema Abel Getu Kebede Girum Zeleke Soworsu Tigist Tsegaye Mengistu Hussien Endris Assen Esileman Abdela Muche Rahel Belete Abebe Leila Kenzu Kemal Abdisa Gemedi Jara Abdulwase Mohammed Seid Source Type: research

A Systematic Guideline by the ASPN Workgroup on the Evidence, Education, and Treatment Algorithm for Painful Diabetic Neuropathy: SWEET
CONCLUSION: The ASPN SWEET Guideline represents the most comprehensive review of the available treatments for PDN and their appropriate and safe utilization.PMID:38633823 | PMC:PMC11022879 | DOI:10.2147/JPR.S451006 (Source: Biomed Res)
Source: Biomed Res - April 18, 2024 Category: Research Authors: Dawood Sayed Timothy Ray Deer Jonathan M Hagedorn Asim Sayed Ryan S D'Souza Christopher M Lam Nasir Khatri Zohra Hussaini Scott G Pritzlaff Newaj Mohammad Abdullah Vinicius Tieppo Francio Steven Michael Falowski Yussr M Ibrahim Mark N Malinowski Ryan R Bu Source Type: research